takahashi toshiaki 高橋利明

… Alternative Names

高橋利明タカハシトシアキ

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Researcher Number	50507415
Affiliation (Current)	2025: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2017: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員 2016: 静岡県立静岡がんセンター(研究所), その他部局等, 呼吸器内科部長 2015: 静岡県立静岡がんセンター(研究所), その他部局等, その他
Review Section/Research Field	Except Principal Investigator Tumor therapeutics
Keywords	Except Principal Investigator メタボローム解析 / オシメルチニブ / 耐性 / EGFR-TKI / 肺腺癌 / がん代謝標的療法

Development of metabolic-targeting therapy for overcoming resistance to EGFR-TKIs in non-small cell lung cancer cells
- Principal Investigator
  
  Serizawa Masakuni
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Shizuoka Cancer Center Research Institute

All 2018 2017 2016

All Journal Article Presentation

[Journal Article] Plasma epidermal growth factor receptor mutation testing with achip-based digital PCR system in patients with advanced non-smallcell lung cancer2017
- Author(s)
  Kasahara N, Kenmotsu H, Serizawa M, Umehara R, Ono A, Hisamatsu Y, Wakuda K, Omori S, Nakashima K, Taira T, Naito T, Murakami H, Koh Y, Mori K, Endo M, Nakajima T, Yamada M, Kusuhara M, Takahashi T.
- Journal Title
  
  Lung Cancer
  
  Volume: 106 Pages: 138-144
- DOI
  10.1016/j.lungcan.2017.02.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21688, KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K06893
[Journal Article] Comparison of clinically relevant mutation profiles between preoperative biopsy and corresponding surgically resected specimens in Japanese patients with non-small cell lung cancer by amplicon-based massively parallel sequencing.2017
- Author(s)
  Isaka M
- Journal Title
  
  Clin Lung Cancer
  
  Volume: 18 Issue: 5 Pages: 519-526
- DOI
  10.1016/j.cllc.2016.11.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K09226, KAKENHI-PROJECT-15K06893
[Journal Article] Drastic initial response and subsequent response to two ALK inhibitors in a patient with a highly aggressive ALK-rearranged inflammatory myofibroblastic tumor arising in the pleural cavity.2016
- Author(s)
  Ono A, Murakami H, Serizawa M, Wakuda K, Kenmotsu H, Naito T, Taira T, Koh Y, Ohde Y, Nakajima T, Endo M, Takahashi T
- Journal Title
  
  Lung Cancer.
  
  Volume: 99 Pages: 151-154
- DOI
  10.1016/j.lungcan.2016.07.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06893
[Journal Article] Frequency of EGFR T790M mutation and multimutational profiles of rebiopsy samples from non-small cell lung cancer developing acquired resistance to EGFR tyrosine kinase inhibitors in Japanese patients.2016
- Author(s)
  Ko R, Kenmotsu H, Serizawa M, Koh Y, Wakuda K, Ono A, Taira T, Naito T, Murakami H, Isaka M, Endo M, Nakajima T, Ohde Y, Yamamoto N, Takahashi K, Takahashi T
- Journal Title
  
  BMC Cancer.
  
  Volume: 16 Pages: 864-864
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06893
[Presentation] Development of metabolic-targeting therapy for overcoming resistance to osimertinib in non-small cell lung cancer cells2018
- Author(s)
  Masakuni Serizawa, Rina Umehara, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Ken Yamaguchi, Kyoichi Kaira, Toshiaki Takahashi, Masatoshi Kusuhara
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06893
[Presentation] 非小細胞肺癌治療におけるEGFRチロシンキナーゼ阻害剤耐性の克服を目的とする代謝標的治療法の開発2017
- Author(s)
  梅原里奈、楠原正俊、大島啓一、浦上研一、解良恭一、高橋利明、山口建、芹澤昌邦
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-15K06893

1. Serizawa Masakuni (00569915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 楠原正俊 (40169991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 解良恭一 (40400783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

takahashi toshiaki 高橋利明

高橋利明タカハシトシアキ

Research Projects

Research Products

Co-Researchers

Development of metabolic-targeting therapy for overcoming resistance to EGFR-TKIs in non-small cell lung cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Plasma epidermal growth factor receptor mutation testing with achip-based digital PCR system in patients with advanced non-smallcell lung cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of clinically relevant mutation profiles between preoperative biopsy and corresponding surgically resected specimens in Japanese patients with non-small cell lung cancer by amplicon-based massively parallel sequencing.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drastic initial response and subsequent response to two ALK inhibitors in a patient with a highly aggressive ALK-rearranged inflammatory myofibroblastic tumor arising in the pleural cavity.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Frequency of EGFR T790M mutation and multimutational profiles of rebiopsy samples from non-small cell lung cancer developing acquired resistance to EGFR tyrosine kinase inhibitors in Japanese patients.2016

Author(s)

Journal Title

Data Source

[Presentation] Development of metabolic-targeting therapy for overcoming resistance to osimertinib in non-small cell lung cancer cells2018

Author(s)

Organizer

Data Source

[Presentation] 非小細胞肺癌治療におけるEGFRチロシンキナーゼ阻害剤耐性の克服を目的とする代謝標的治療法の開発2017

Author(s)

Organizer

Data Source

takahashi toshiaki 高橋 利明

高橋 利明 タカハシ トシアキ

Research Projects

Research Products

Co-Researchers

Development of metabolic-targeting therapy for overcoming resistance to EGFR-TKIs in non-small cell lung cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Plasma epidermal growth factor receptor mutation testing with achip-based digital PCR system in patients with advanced non-smallcell lung cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of clinically relevant mutation profiles between preoperative biopsy and corresponding surgically resected specimens in Japanese patients with non-small cell lung cancer by amplicon-based massively parallel sequencing.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drastic initial response and subsequent response to two ALK inhibitors in a patient with a highly aggressive ALK-rearranged inflammatory myofibroblastic tumor arising in the pleural cavity.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Frequency of EGFR T790M mutation and multimutational profiles of rebiopsy samples from non-small cell lung cancer developing acquired resistance to EGFR tyrosine kinase inhibitors in Japanese patients.2016

Author(s)

Journal Title

Data Source

[Presentation] Development of metabolic-targeting therapy for overcoming resistance to osimertinib in non-small cell lung cancer cells2018

Author(s)

Organizer

Data Source

[Presentation] 非小細胞肺癌治療におけるEGFRチロシンキナーゼ阻害剤耐性の克服を目的とする代謝標的治療法の開発2017

Author(s)

Organizer

Data Source

takahashi toshiaki 高橋利明

高橋利明タカハシトシアキ