Niimi Atsuko 新美敦子

Researcher Number	50508984
Affiliation (Current)	2025: 藤田医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 藤田医科大学, 医学部, 准教授 2015 – 2017: 群馬大学, 未来先端研究機構, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / Risk sciences of radiation and chemicals / Radiation science Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator ゲノム不安定化 / POLD4 / DNA修復 / 重粒子線 / 複製ストレス / DSB修復 / DNA損傷 / EGFR / DNA二本鎖切断 / 53BP1 … More / 染色体転座 / 3Dライブイメージング / ゲノム不安定性 / 医学放射線生物学 / 染色体異常 / ライブイメージング … More Except Principal Investigator 肺がん / 転写因子 / アクチン / 細胞骨格 / 創薬 / スフィンゴ脂質 / 細胞遊走 / セラミド / 転移 / CERS6 / 肺癌 Less

Fork Reversal因子POLD4を指標とした新規肺癌分子標的治療法の開発Principal Investigator
- Principal Investigator
  
  新美敦子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fujita Health University
Analysis of gene module for genomic instability in lung cancerPrincipal Investigator
- Principal Investigator
  
  Niimi Atsuko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Fujita Health University
Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells
- Principal Investigator
  
  Suzuki Motoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fujita Health University
Analysis of individual fate determination of irradiated cells by using live cell imaging techniquePrincipal Investigator
- Principal Investigator
  
  Niimi Atsuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Gunma University
Proof of mutual interference between two DNA double strand break sites leading to chromosomal translocationPrincipal Investigator
- Principal Investigator
  
  Niimi Atsuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Gunma University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] LASP1, CERS6, and Actin Form a Ternary Complex That Promotes Cancer Cell Migration2023
- Author(s)
  Niimi Atsuko、Limsirichaikul Siripan、Kano Keiko、Mizutani Yasuyoshi、Takeuchi Toshiyuki、Sawangsri Patinya、Tran Dat Quoc、Kawamoto Yoshiyuki、Suzuki Motoshi
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 10 Pages: 2781-2781
- DOI
  10.3390/cancers15102781
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08217, KAKENHI-PROJECT-22K07263
[Journal Article] CEBPγ facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation2021
- Author(s)
  Hanxiao Sh, Atsuko Niimi, Toshiyuki Takeuchi, Kazuya Shiogama, Yasuyoshi Mizutani, Taisuke Kajino, Kenichi Inada, Tetsunari Hase, Takahiro Hatta, Hirofumi Shibata, Takayuki Fukui, Toyofumi Fengshi Chen-Yoshikawa, Kazuki Nagano, Takashi Murate, Yoshiyuki Kawamoto, Shuta Tomida, Takashi Takahashi, Motoshi Suzuki
- Journal Title
  
  Cancer Science
  
  Volume: 未定 Issue: 7 Pages: 2770-2780
- DOI
  10.1111/cas.14928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07030, KAKENHI-PROJECT-18K07193, KAKENHI-PROJECT-16H02468, KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-20H03771
[Journal Article] CEBPgamma facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation2021
- Author(s)
  Shi H, Niimi A, Takeuchi T, Shiogama K, Mizutani Y, Kajino T, Inada K, Hase T, Hatta T, Shibata H, Fukui T, Chen-Yoshikawa T-F, Nagano K, Murate T, Kawamoto Y, Tomida S, Takahashi T, Suzuki, M
- Journal Title
  
  Cancer Science
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02698
[Journal Article] Combined α-methylacyl-CoA racemase inhibition and docetaxel treatment reduce cell proliferation and decrease expression of heat shock protein 27 in androgen receptor-variant-7?positive prostate cancer cells2021
- Author(s)
  Yoshizawa Atsuhiko、Takahara Kiyoshi、Saruta Masanobu、Zennami Kenji、Nukaya Takuhisa、Fukaya Kosuke、Ichino Manabu、Fukami Naohiko、Niimi Atsuko、Sasaki Hitomi、Kusaka Mamoru、Suzuki Motoshi、Sumitomo Makoto、Shiroki Ryoichi
- Journal Title
  
  Prostate International
  
  Volume: 9 Issue: 1 Pages: 18-24
- DOI
  10.1016/j.prnil.2020.07.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09722, KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-17K11163, KAKENHI-PROJECT-20K18127
[Journal Article] CERS6 required for cell migration and metastasis in lung cancer.2020
- Author(s)
  Suzuki M, Cao K, Kato S, Mizutani N, Tanaka K, Arima C, Tai MC, Nakatani N, Yanagisawa K, Takeuchi T, Shi H, Mizutani Y, Niimi A, Taniguchi T, Fukui T, Yokoi K, Wakahara K, Hasegawa Y, Mizutani Y, Iwaki S, Fujii S, Satou A, Tamiya-Koizumi K, Murate T, Kyogashima M, Tomida S, Takahashi T.
- Journal Title
  
  J Cell Mol Med.
  
  Volume: 24 Issue: 20 Pages: 11949-11959
- DOI
  10.1111/jcmm.15817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02468, KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-18K08174
[Journal Article] Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP12017
- Author(s)
  Motohiro Yamauchi, Atsushi Shibata, Keiji Suzuki, Masatoshi Suzuki, Atsuko Niimi, Hisayoshi Kondo, Miwa Miura, Miyako Hirakawa, Keiko Tsujita, Shunichi Yamashita, Naoki Matsuda
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 41812-41812
- DOI
  10.1038/srep41812
- NAID
  120006987560
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02816, KAKENHI-PROJECT-26281023, KAKENHI-PROJECT-26701005, KAKENHI-PROJECT-26670549, KAKENHI-PROJECT-15K00542, KAKENHI-PROJECT-15K15447, KAKENHI-PROJECT-16H03062
[Journal Article] 3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation2017
- Author(s)
  Hagiwara Yoshihiko、Niimi Atsuko、Isono Mayu、Yamauchi Motohiro、Yasuhara Takaaki、Limsirichaikul Siripan、Oike Takahiro、Sato Hiro、Held Kathryn D.、Nakano Takashi、Shibata Atsushi
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 65 Pages: 109370-109381
- DOI
  10.18632/oncotarget.22679
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26701005, KAKENHI-PROJECT-15H02816, KAKENHI-PROJECT-15K15447, KAKENHI-PROJECT-17H04713
[Journal Article] BRCA1 directs the repair pathway to homologous recombination by promoting 53BP1 dephosphorylation2017
- Author(s)
  Mayu Isono, Atsuko Niimi, Takahiro Oike, Yoshihiko Hagiwara, Hiro Sato, Ryota Sekine, Yukari Yoshida, Shin-Ya Isobe, Chikashi Obuse, Ryotaro Nishi, Elena Petricci, Shinichiro Nakada, Takashi Nakano, Atsushi Shibata
- Journal Title
  
  Cell Reports
  
  Volume: 18 Issue: 2 Pages: 520-532
- DOI
  10.1016/j.celrep.2016.12.042
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02816, KAKENHI-PROJECT-16H04739, KAKENHI-PROJECT-16H05888, KAKENHI-PROJECT-26701005, KAKENHI-PROJECT-15K15449, KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-26670549, KAKENHI-PROJECT-15K09988, KAKENHI-PROJECT-15K15447, KAKENHI-PLANNED-25116004, KAKENHI-PROJECT-26241014
[Journal Article] Identification of DNA double strand breaks at chromosome boundaries along the track of particle irradiation2016
- Author(s)
  Atsuko Niimi, Motohiro Yamauchi, Siripan Limsirichaikul, Ryota Sekine, Takahiro Oike, Hiro Sato, Keiji Suzuki, Kathryn D. Held, Takashi Nakano, Atsushi Shibata
- Journal Title
  
  Genes Chromosomes & Cancer
  
  Volume: 55 Issue: 8 Pages: 650-660
- DOI
  10.1002/gcc.22367
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02816, KAKENHI-PROJECT-16H05388, KAKENHI-PROJECT-26701005, KAKENHI-PROJECT-26670549, KAKENHI-PROJECT-15K15447, KAKENHI-PROJECT-16H03062
[Journal Article] Visualization of complex DNA double-strand breaks in a tumor treated with carbon ion radiotherapy2016
- Author(s)
  Takahiro Oike, Atsuko Niimi, Noriyuki Okonogi, Kazutoshi Murata, Akihiko Matsumura, Shin-Ei Noda, Daijiro Kobayashi, Mototaro Iwanaga, Keisuke Tsuchida, Tatsuaki Kanai, Tatsuya Ohno, Atsushi Shibata, Takashi Nakano
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 22275-22275
- DOI
  10.1038/srep22275
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15447, KAKENHI-PROJECT-26670549, KAKENHI-PROJECT-15H02816, KAKENHI-PROJECT-24390288, KAKENHI-PROJECT-26701005, KAKENHI-PROJECT-16H05388
[Patent] 肺がんを治療するための併用薬、肺がん治療用医薬組成物および併用薬の適応患者を選択するための情報提供方法2022
- Inventor(s)
  鈴木　元、新美　敦子
- Industrial Property Rights Holder
  学校法人藤田学園
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] YBX1 is a tuner to suppress PD-L1 expression in lung cancer2023
- Author(s)
  Yasuyoshi Mizutani, Toshiyuki Takeuchi, Atsuko Niimi, Siripan Limsirichaikul, Patinya Sawangsri, Tran Quoc Dat, Ken-ichi Inada, Tetsuya Tsukamoto, Masashi Kondo, Motoshi Suzuki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] SMARCA4 and SMARCAD1 confer pathways that suppress DNA replication stress in non-small cell lung cancer2023
- Author(s)
  Patinya Sawangsri, Atsuko Niimi, Siripan Limsirichaikul, Dat Quoc Tran, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] POLD4-PRIMPOL経路を標的とした新規非小細胞肺がん治療法の検討2023
- Author(s)
  新美敦子、Siripan Limsirichaikul、Patinya Sawangsri、Dat Quoc Tran、水谷泰嘉、竹内俊幸、鈴木元
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] Targeting the POLD4-PRIMPOL pathway in non-small cell lung cancer2023
- Author(s)
  Atsuko Niimi, Siripan Limsirichaikul, Patinya Sawangsri, Tran Quoc Dat, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] CERS6-LASP1-actin coordinated to facilitate lung cancer cell migration Alternative title; LASP1, CERS6, and actin form ternary complex that promotes cancer cell migration2023
- Author(s)
  Siripan Limsirichaikul, Atsuko Niimi, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Patinya Sawangsri, Tran Quoc Dat, Motoshi Suzuki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] LASP1 tethers CERS6 at lamellipodia and promotes cancer cell migration2022
- Author(s)
  Siripan Limsirichaikul, Atsuko Niimi, Toshiyuki Takeuchi, Yasuyoshi Mizutani, Patinya Sawangsri, Tran Quoc Dat, Motoshi Suzuki
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] Functional analysis of YBX1 in PD-L1 expression in lung cancer2022
- Author(s)
  Yasuyoshi Mziutani, Toshiyuki Takeuchi, Atsuko Niimi, Siripan Limsirichaikul, Patinya Sawangsri, Tran Quoc Dat, Ken-ichi Inada, Motoshi Suzuki
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] POLD4-dependent DDR pathway may be targeted in non-small cell lung cancer2022
- Author(s)
  Atsuko Niimi, Siripan Limsirichaikul, Patinya Sawangsri, Tran Quoc Dat, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] CERS6 and CEBPg required for cell migration and metastasis through an alteration in the ceramide metabolic profile.2021
- Author(s)
  Hanxiao Shi, Toshiyuki Takeuchi, Atsuko Niimi, Yasuyoshi Mizutani, Taisuke Kajino, Shuta Tomida, Takashi Takahashi, Motoshi Suzuki
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] POLD4 pathway is required for repair of CDDP-induced DNA damage2021
- Author(s)
  新美敦子、水谷泰嘉、竹内俊幸、鈴木元
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07193
[Presentation] POLD4 pathway is required for repair of CDDP-induced DNA damage.2021
- Author(s)
  Atsuko Niimi, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] CEBPγ and YBX1 regulate lung cancer metastasis via CERS6 expression and lamellipodia formation2020
- Author(s)
  石含笑、新美敦子、竹内俊幸、水谷泰嘉、塩竈和也、稲田健一、長谷哲成、長谷川好規、高橋隆、鈴木元
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07193
[Presentation] A suppressor role of POLD4, the smallest subunit of DNA polymerase d complex, in lung cancer2020
- Author(s)
  Atsuko Niimi, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] A suppressor role of POLD4, the smallest subunit of DNA polymerase δ complex, in lung cancer2020
- Author(s)
  新美敦子、水谷泰嘉、竹内俊幸、鈴木元
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07193
[Presentation] 病変組織内の特異的抗体産生細胞を可視化する「酵素抗原法」の技術開発2019
- Author(s)
  水谷泰嘉、塩竈和也、竹内俊幸、新美敦子、石含笑、稲田健一、鈴木元
- Organizer
  第60回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] nanoLC-MS を用いたインタクトタンパク質の翻訳後修飾解析2019
- Author(s)
  加納圭子,新美敦子, 鈴木元, 小林宏資, 和田啓男, 桑田啓子
- Organizer
  第70回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] DNAポリメラーゼδ複合体サブユニットPOLD4の肺がん発生における役割解析2019
- Author(s)
  新美敦子、岩瀬咲良、竹内俊幸、水谷泰嘉、鈴木元
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07193
[Presentation] DNAポリメラーゼδ複合体サブユニットPOLD4の肺がん発生における役割解析2019
- Author(s)
  新美敦子、岩瀬咲良、竹内俊幸、水谷泰嘉、鈴木元
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] A metastasis protein CERS6 is transcriptionally regulated by miR-101 and YB-12018
- Author(s)
  石含笑、竹内俊幸、新美敦子、水谷泰嘉、村手隆、高橋隆、鈴木元
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07193
[Presentation] A metastasis protein CERS6 is transcriptionally regulated by miR-101 and YB-1.2018
- Author(s)
  Hanxiao Shi, Toshiyuki Takeuchi, Atsuko Niimi, Yasuyoshi Mizutani, Takashi Murate, Takashi Suzuki, Motoshi Suzuki
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] 重粒子線に特徴的なDNA損傷の可視化と細胞運命決定に与える影響の解析2017
- Author(s)
  新美敦子, 萩原慶彦, シリパンリムシリチャイクル, 尾池貴洋, 佐藤浩央, 中野隆史, 柴田淳史
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K15447
[Presentation] 超解像度顕微鏡による重粒子線誘発クラスターDNA二本鎖切断の空間分布解析2017
- Author(s)
  新美敦子, 萩原慶彦, シリパンリムシリチャイクル, 尾池貴洋, 佐藤浩央, 中野隆史, 柴田淳史
- Organizer
  日本放射線影響学会　第60回大会
- Data Source
  KAKENHI-PROJECT-15K15447
[Presentation] 重粒子線に特徴的なDNA損傷の可視化と細胞運命決定に与える影響の解析2017
- Author(s)
  新美敦子, 萩原慶彦, シリパンリムシリチャイクル, 尾池貴洋, 佐藤浩央, 中野隆史, 柴田淳史
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15H02816
[Presentation] 超解像度顕微鏡による重粒子線誘発クラスターDNA二本鎖切断の空間的分布の解析2017
- Author(s)
  新美敦子, 萩原慶彦, シリパンリムシリチャイクル, 尾池貴洋, 佐藤浩央, 中野隆史, 柴田淳史
- Organizer
  第89回　日本遺伝学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K15447
[Presentation] 超解像度顕微鏡による重粒子線誘発クラスターDNA二本鎖切断の空間分布解析2017
- Author(s)
  新美敦子, 萩原慶彦, シリパンリムシリチャイクル, 尾池貴洋, 佐藤浩央, 中野隆史, 柴田淳史
- Organizer
  日本放射線影響学会　第60回大会
- Data Source
  KAKENHI-PROJECT-15H02816
[Presentation] 超解像度顕微鏡による重粒子線誘発クラスターDNA二本鎖切断の空間的分布の解析2017
- Author(s)
  新美敦子, 萩原慶彦, シリパンリムシリチャイクル, 尾池貴洋, 佐藤浩央, 中野隆史, 柴田淳史
- Organizer
  第89回　日本遺伝学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02816
[Presentation] 重粒子線照射により誘発される特異なDNA損傷形状の可視化2016
- Author(s)
  新美敦子, 山内基弘, シリパンリムシリチャイクル, 関根崚太, 磯野真由, 尾池貴洋, 佐藤浩央, 鈴木啓司, 中野隆史, 柴田淳史
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K15447
[Presentation] Analysis of DNA synthesis during homologous recombination in G2 cells after ionizing irradiaiton2016
- Author(s)
  Atsuko Niimi, Siripan Limsirichaikul, Takashi Nakano, Atsushi Shibata
- Organizer
  The 10th 3R symposium
- Place of Presentation
  Hotel Ichibata (Matsue)
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02816
[Presentation] 重粒子線照射により誘発される特異なDNA損傷形状の可視化2016
- Author(s)
  新美敦子, 山内基弘, シリパンリムシリチャイクル, 関根崚太, 磯野真由, 尾池貴洋, 佐藤浩央, 鈴木啓司, 中野隆史1, 柴田淳史
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H02816
[Presentation] Analysis of DNA synthesis during homologous recombination in G2 cells after ionizing irradiaiton2016
- Author(s)
  Atsuko Niimi, Siripan Limsirichaikul, Takashi Nakano, Atsushi Shibata
- Organizer
  The 10th 3R symposium
- Place of Presentation
  Hotel Ichibata (Matsue)
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15447
[Presentation] Analysis of cluster DNA double strand break formation using high-resolution microscopy2016
- Author(s)
  Atsuko Niimi, Nakajima Izumi Nakako, Motohiro Yamauchi, Siripan Limsirichaikul, Takahiro Oike, Hiro Sato, Penny A. Jeggo, Kathryn D. Held, Takashi Nakano, Atsushi Shibata
- Organizer
  10th Quinquennial Conference on Responses to DNA Damage
- Place of Presentation
  Egmond aan Zee (The Netherlands)
- Year and Date
  2016-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15447
[Presentation] Analysis of cluster DNA double strand break formation using high-resolution microscopy2016
- Author(s)
  Atsuko Niimi, Nakajima Izumi Nakako, Motohiro Yamauchi, Siripan Limsirichaikul, Takahiro Oike, Hiro Sato, Penny A. Jeggo, Kathryn D. Held, Takashi Nakano, Atsushi Shibata
- Organizer
  10th Quinquennial Conference on Responses to DNA Damage
- Place of Presentation
  Egmond aan Zee (The Netherlands)
- Year and Date
  2016-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02816
[Presentation] 高LET重粒子線照射により誘発される２つの異なる染色体間にまたがるクラスターDNA損傷の同定2015
- Author(s)
  新美敦子, 山内基弘, シリパンリムシリチャイクル, 関根崚太, 磯野真由, 尾池貴洋, 佐藤浩央, 鈴木啓司, 中野隆史, 柴田淳史
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド(神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H02816
[Presentation] Visualization of heavy ion induced cluster DNA double strand breaks formation using the super-resolution microscopy2015
- Author(s)
  Atsuko Niimi, Takahiro Oike, Mayu Isono, Yoshihiko Hagiwara, Yukari Yoshida, Akihisa Takahashi, Takashi Nakano, Atsushi Shibata
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto International Conference Center (Kyoto)
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15447
[Presentation] 高LET重粒子線照射により誘発される２つの異なる染色体間にまたがるクラスターDNA損傷の同定2015
- Author(s)
  新美敦子, 山内基弘, シリパンリムシリチャイクル, 関根崚太, 磯野真由, 尾池貴洋, 佐藤浩央, 鈴木啓司, 中野隆史, 柴田淳史
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド(神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15447
[Presentation] Visualization of heavy ion induced cluster DNA double strand breaks formation using the super-resolution microscopy2015
- Author(s)
  Atsuko Niimi, Takahiro Oike, Mayu Isono, Yoshihiko Hagiwara, Yukari Yoshida, Akihisa Takahashi, Takashi Nakano, Atsushi Shibata
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto International Conference Center(Kyoto)
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02816

1. SHIBATA Atsushi (30707633)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
2. YAMAUCHI Motohiro (60437910)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. 竹内俊幸 (20538483)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
4. Suzuki Motoshi (80236017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. 梶野泰祐 (50723673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 水谷泰嘉 (10546229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. 安藤隆幸 (40402226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 村手隆 (30239537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. SHIOGAMA Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 稲田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 高橋隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 日下守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Niimi Atsuko 新美 敦子

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Fork Reversal因子POLD4を指標とした新規肺癌分子標的治療法の開発Principal Investigator

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Analysis of gene module for genomic instability in lung cancerPrincipal Investigator

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Targeting ceramide synthase 6&#8211;dependent metastasis-prone phenotype in lung cancer cells

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Analysis of individual fate determination of irradiated cells by using live cell imaging techniquePrincipal Investigator

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Proof of mutual interference between two DNA double strand break sites leading to chromosomal translocationPrincipal Investigator

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[Journal Article] LASP1, CERS6, and Actin Form a Ternary Complex That Promotes Cancer Cell Migration2023

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[Journal Article] CEBPγ facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation2021

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[Journal Article] CEBPgamma facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation2021

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[Journal Article] Combined α-methylacyl-CoA racemase inhibition and docetaxel treatment reduce cell proliferation and decrease expression of heat shock protein 27 in androgen receptor-variant-7?positive prostate cancer cells2021

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[Journal Article] CERS6 required for cell migration and metastasis in lung cancer.2020

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[Journal Article] Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP12017

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NAID

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[Journal Article] 3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread &#x3B3;H2AX foci after high LET heavy-ion particle radiation2017

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[Journal Article] BRCA1 directs the repair pathway to homologous recombination by promoting 53BP1 dephosphorylation2017

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[Journal Article] Identification of DNA double strand breaks at chromosome boundaries along the track of particle irradiation2016

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[Journal Article] Visualization of complex DNA double-strand breaks in a tumor treated with carbon ion radiotherapy2016

Niimi Atsuko 新美敦子

Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells

[Journal Article] 3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation2017