Kimura Ayuko 木村鮎子

… Alternative Names

Researcher Number	50553616
Other IDs
Affiliation (Current)	2019: 群馬パース大学, 保健科学部, 講師
Affiliation (based on the past Project Information) *help	2018: 群馬パース大学, 保健科学部, 講師 2017: 横浜市立大学, 先端医科学研究センター, 特任助教 2013 – 2016: 横浜市立大学, 生命医科学研究科, 特任助教
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Functional biochemistry / Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator プロテオミクス / 癌 / プロテアソーム / ミリストイル化 / 悪性度 / Brg1 / Rpt2 / 卵巣明細胞癌 / ユビキチン化 / N-ミリストイル化 … More

N-myristoylation-induced nuclear localization of proteasome and stress response in tumor microenvironmentPrincipal InvestigatorOngoing
- Principal Investigator
  
  木村鮎子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gumma Paz College
Phosphorylation of SWI/SNF chromatin remodeling component Brg1 and mechanisms involved in malignant transformation of cancerPrincipal Investigator
- Principal Investigator
  
  KIMURA Ayuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yokohama City University
Functions of the nuclear ubiquitin proteasome system regulated by N-myristoylationPrincipal Investigator
- Principal Investigator
  
  KIMURA Ayuko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University

All 2016 2015 2014 2013

All Journal Article Presentation Book

[Book] 医学のあゆみ 9章. 「疾患研究における翻訳後修飾の解析」2014
- Author(s)
  木村　鮎子、平野　久
- Total Pages
  1034
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-25840039
[Journal Article] Biological significance of co- and post-translational modifications of the yeast 26S proteasome2016
- Author(s)
  Hirano H, Kimura Y, Kimura A
- Journal Title
  
  Journal of Proteomics
  
  Volume: 134 Pages: 37-46
- DOI
  10.1016/j.jprot.2015.11.016
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19028, KAKENHI-PROJECT-16H05230
[Journal Article] N-myristoylation of the Rpt2 subunit of the yeast 26S proteasome is implicated in the subcellular compartment-specific protein quality control system2016
- Author(s)
  Kimura A, Kurata Y, Nakabayashi J, Kagawa H, Hirano H.
- Journal Title
  
  Journal of Proteomics
  
  Volume: 130 Pages: 33-41
- DOI
  10.1016/j.jprot.2015.08.021
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19028, KAKENHI-PROJECT-26830099
[Journal Article] Lyn Kinase suppresses the transcriptional activity of IRF5 in the TLR-MyD88 pathway to restrain the development of autoimmunity2016
- Author(s)
  Ban T., Sato G.R., Nishiyama A., Akiyama A., Takasuna M., Umehara M., Suzuki S., Ichino M., Matsunaga S., Kimura A., Kimura Y., Yanai H., Miyashita S., Kuromitsu J., Tsukahara K., Yoshimatsu K., Endo I., Yamamoto T., Hirano H., Ryo A., Taniguchi T., Tamura T.
- Journal Title
  
  Immunity
  
  Volume: 45 Pages: 319-32
- DOI
  10.1016/j.immuni.2016.07.015
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16H07105, KAKENHI-PROJECT-26460373, KAKENHI-PROJECT-15K19028, KAKENHI-PROJECT-16K19161, KAKENHI-PROJECT-16H05230, KAKENHI-PLANNED-24118002
[Journal Article] Comprehensive behavioral study and proteomic analyses of CRMP2-deficient mice2016
- Author(s)
  Nakamura H, Yamashita N, Kimura A, Kimura Y, Hirano H, Makihara H, Kawamoto Y, Jitsuki-Takahashi A, Yonezaki K, Takase K, Miyazaki T, Nakamura F, Tanaka F, Goshima Y.
- Journal Title
  
  Genes to Cells
  
  Volume: 21 Pages: 1059-1079
- DOI
  10.1111/gtc.12403
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19028, KAKENHI-PROJECT-16H05230
[Journal Article] Mass Spectrometric Analysis of the Phosphorylation Levels of the SWI/SNF Chromatin Remodeling/Tumor Suppressor Proteins ARID1A and Brg1 in Ovarian Clear Cell Adenocarcinoma Cell Lines.2014
- Author(s)
  Kimura, A., Arakawa, N., and Hirano, H.
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 13(11) Pages: 4959-4969
- DOI
  10.1021/pr500470h
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460695, KAKENHI-PROJECT-25840039
[Presentation] 卵巣明細胞腺癌の悪性化機構の解明を目指したリン酸化プロテオーム解析2016
- Author(s)
  木村　鮎子
- Organizer
  第13回　北里疾患プロテオーム研究会/第66回　日本電気泳動学会シンポジウム
- Place of Presentation
  北里大学
- Year and Date
  2016-03-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K19028
[Presentation] 癌悪性化機構の解明を目指したリン酸化プロテオーム解析2016
- Author(s)
  木村　鮎子
- Organizer
  日本プロテオーム学会2016年大会（JHUPO第14回大会）
- Place of Presentation
  北里大学
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K19028
[Presentation] (受賞講演)癌悪性化機構の解明を目指したリン酸化プロテオーム解析2016
- Author(s)
  木村　鮎子
- Organizer
  日本プロテオーム学会2016年大会（JHUPO第14回大会）
- Place of Presentation
  北里大学白金キャンパス (東京都港区)
- Year and Date
  2016-07-29
- Data Source
  KAKENHI-PROJECT-15K19028
[Presentation] 酵母26SプロテアソームサブユニットのN-ミリストイル化修飾とタンパク質品質管理2015
- Author(s)
  木村　鮎子、倉田　洋一、香川　裕之、平野　久
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K19028
[Presentation] 卵巣明細胞腺癌細胞株特異的なクロマチン再構成因子Brg1のリン酸化レベル低下2014
- Author(s)
  木村　鮎子, 荒川　憲昭, 平野　久
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25840039
[Presentation] MRM法による卵巣明細胞腺癌細胞株特異的なSWI/SNFクロマチン再構成複合体因子Brg1のリン酸化レベル低下の解析2014
- Author(s)
  木村　鮎子, 荒川　憲昭, 平野　久
- Organizer
  日本プロテオーム学会第12回大会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2014-07-18
- Data Source
  KAKENHI-PROJECT-25840039
[Presentation] Identification and Characterization of the Posttranslational Modifications of Yeast 26S Proteasome2013
- Author(s)
  Ayuko Kimura, Yu Kato, Yoichi Kurata, Yayoi Kimura, Hisashi Hirano
- Organizer
  HUPO 12th Annual World Congress
- Place of Presentation
  Pacifico Yokohama, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25840039

1. YANAI Hideyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. YAMAMOTO Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. SUZUKI Hidefumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. BAN Tatsuma

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. OSHIMA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 木村弥生

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 荒川憲昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 倉田洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 谷口維紹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 山本一彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 松永智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 田村智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 西山晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Ayuko 木村 鮎子

KIMURA Ayuko 木村 鮎子

Research Projects

Research Products

Co-Researchers

N-myristoylation-induced nuclear localization of proteasome and stress response in tumor microenvironmentPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Phosphorylation of SWI/SNF chromatin remodeling component Brg1 and mechanisms involved in malignant transformation of cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functions of the nuclear ubiquitin proteasome system regulated by N-myristoylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 医学のあゆみ 9章. 「疾患研究における翻訳後修飾の解析」2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Biological significance of co- and post-translational modifications of the yeast 26S proteasome2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-myristoylation of the Rpt2 subunit of the yeast 26S proteasome is implicated in the subcellular compartment-specific protein quality control system2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lyn Kinase suppresses the transcriptional activity of IRF5 in the TLR-MyD88 pathway to restrain the development of autoimmunity2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive behavioral study and proteomic analyses of CRMP2-deficient mice2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mass Spectrometric Analysis of the Phosphorylation Levels of the SWI/SNF Chromatin Remodeling/Tumor Suppressor Proteins ARID1A and Brg1 in Ovarian Clear Cell Adenocarcinoma Cell Lines.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 卵巣明細胞腺癌の悪性化機構の解明を目指したリン酸化プロテオーム解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 癌悪性化機構の解明を目指したリン酸化プロテオーム解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] (受賞講演)癌悪性化機構の解明を目指したリン酸化プロテオーム解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 酵母26SプロテアソームサブユニットのN-ミリストイル化修飾とタンパク質品質管理2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 卵巣明細胞腺癌細胞株特異的なクロマチン再構成因子Brg1のリン酸化レベル低下2014

Author(s)

Organizer

Kimura Ayuko 木村鮎子

KIMURA Ayuko 木村鮎子