SAKAI Satoshi 酒井聡

… Alternative Names

Sakai Satoshi 酒井聡

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Researcher Number	50566081
Other IDs
Affiliation (Current)	2025: 浜松医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 浜松医科大学, 医学部, 助教 2011: 新潟薬科大学, 薬学部, 助教 2010: 名古屋市立大学, 大学院・薬学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related Except Principal Investigator Medium-sized Section 50:Oncology and related fields / Basic Section 50010:Tumor biology-related / Biological pharmacy
Keywords	Principal Investigator lncRNA / シグナル伝達 / TGFβ / 肝がん / 肝線維化 / HBV / HBV複製 / 肝がん悪性化 / がん抑制遺伝子 / がん遺伝子 / がん悪性化 / 遺伝子発現 … More Except Principal Investigator … More がん / 相同組換え修復 / X染色体 / 細胞運命 / シグナル伝達 / ノンコーディングRNA / 細胞運命制御 / エピゲノム制御 / 長鎖ノンコーディングRNA / 予後診断 / 女性腫瘍 / 相同組換え / 乳がん / RORα / EBPβ / C / 膵β細胞 / Cdc25A / 肝細胞 / Smad3 / 脂肪滴 / 脂肪組胞 / perilipin / IL-2 / PPARγ / 小胞体ストレス / TRB1 / メタボリックシンドローム / β細胞 / 脂肪細胞 / TGFβ / TRB3 / ストレス Less

シグナル依存的な遺伝子発現制御機構の特異性と多様性を担う長鎖ncRNAの同定Principal Investigator
- Principal Investigator
  
  酒井聡
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hamamatsu University School of Medicine
Elucidation of the malignant transformation mechanism of female tumors mediated by both X-chromosome activation
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Hamamatsu University School of Medicine
Cell fate control by lncRNA regulating genetic specificities of epigenetic factors
- Principal Investigator
  
  北川雅敏
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hamamatsu University School of Medicine
Molecular mechanisms of development of malignant female cancers associated with X-chromosome reactivation
- Principal Investigator
  
  Kitagawa Masatoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Hamamatsu University School of Medicine
Molecular mechanisms of HBV replication and liver cancer malignant progression by a novel lncRNA ELIT-1Principal Investigator
- Principal Investigator
  
  Sakai Satoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hamamatsu University School of Medicine
Crosstalk between stress and cytokine signaling in metabolic syndrome
- Principal Investigator
  
  HAYASHI Hidetoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University

All 2023 2022 2021 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Expression of tumor suppressor FHIT is regulated by the LINC00173-SNAIL axis in human lung adenocarcinoma.2023
- Author(s)
  Suzuki T, Sakai S, Kitagawa M. et al.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 24 Issue: 23 Pages: 17011-17011
- DOI
  10.3390/ijms242317011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-20K07569
[Journal Article] APOBEC3B expression is promoted by lincNMR collaborating with TGF-β-Smad pathway2022
- Author(s)
  Ota K, Sakai S, Ohhata T, Suzuki T, Uchida C, Niida H, Kitagawa M.
- Journal Title
  
  Carcinogenesis .
  
  Volume: bgac086 Issue: 1 Pages: 1-14
- DOI
  10.1093/carcin/bgac086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07308, KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-20K07569
[Journal Article] Homologous recombination is reduced in female embryonic stem cells by two active X chromosomes2021
- Author(s)
  Tamura Y., Ohhata, T., Niida, H., Sakai, S., Uchida C., Masumoto, K., Kotou, F., Wuts, A. and Kitagawa, M
- Journal Title
  
  EMBO Rep
  
  Volume: 22 Issue: 9
- DOI
  10.15252/embr.202052190
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08727, KAKENHI-PROJECT-19K22559, KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-21K19404
[Journal Article] Anaphase promoting complex/cyclosome-Cdh1 mediates the ubiquitination and degradation of TRB3.2010
- Author(s)
  N.Ohoka, S.Sakai, K.Onozaki, M.Nakanishi, H.Hayashi
- Journal Title
  
  Biochemical & Biophysical Research Communication
  
  Volume: 392(3) Pages: 289-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] Dual mode of regulation of Cdc25A protein by TRB32010
- Author(s)
  S.Sakai, N.Ohoka, K.Onozaki, M.Kitagawa, M.Nakanishi, H.Hayashi
- Journal Title
  
  Biological and Pharmaceutical Bulletin 33(7)(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] Anaphase promoting complex/cyclosome-Cdh1 mediates the ubiquitination and degradation of TRB32010
- Author(s)
  N. Ohoka, S. Sakai, K. Onozaki, M. Nakanishi, H. Hayashi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 392 Pages: 289-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] Dual mode of regulation of Cdc25A protein by TRB32010
- Author(s)
  S. Sakai, N. Ohoka, K. Onozaki, M. Kitagawa, M. Nakanishi, H. Hayashi
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 33 Pages: 1112-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] Anaphase promoting complex/cyclosome-Cdh1 mediates the ubiquitination and degradation of TRB32010
- Author(s)
  N.Ohoka, S.Sakai, K.Onozaki, M.Nakanishi, H.Hayashi
- Journal Title
  
  Biochemical and Biophysical Research Communications 392(3)
  
  Pages: 289-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] Dual mode of regulation of Cdc25A protein by TRB3.2010
- Author(s)
  S.Sakai, N.Ohoka, K.Onozaki, M.Kitagawa, M.Nakanishi, H.Hayashi
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 33(7) Pages: 1112-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] Xist-dependent activation status of two X chromosomes is associated with homologous recombination efficiency in female ES cells.2023
- Author(s)
  Masatoshi Kitagawa, Yuka Tamura, Satoshi Sakai, Hiroyuki Niida, Tatsuya Ohhata
- Organizer
  28th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19404
[Presentation] lncRNA ELIT-2はTGFβ-Smad経路を介して上皮間葉転換(EMT)を促進する2023
- Author(s)
  酒井　聡、大畑　樹也、丹伊田　浩行、北川　雅敏
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07569
[Presentation] APOBEC3B expression is promoted by lincNMR collaborating with TGFβーSmad pathway2023
- Author(s)
  Satoshi Sakai, Kosuke Ota, Tatsuya Ohhata, Hiroyuki Niida, Masatoshi Kitagawa
- Organizer
  28th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07569
[Presentation] TGFβシグナルに寄与するlncRNA2023
- Author(s)
  酒井　聡、太田　幸佑、鈴木　貴人、大畑　樹也、北川　雅敏
- Organizer
  第96回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07569
[Presentation] Comprehensive analysis of long non-coding RNAs induced by TGFβ and their functional analysis2022
- Author(s)
  Satoshi Sakai, Kosuke Ota, Tatsuya Ohhata, Hiroyuki Niida, Masatoshi Kitagawa
- Organizer
  2022 Cold Spring Harbor Asia Conference (RNA BIOLOGY)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07569
[Presentation] lincNMRはTGF-β-Smad pathwayを介してAPOBEC3Bの発現を促進する2022
- Author(s)
  太田　幸佑、酒井　聡、大畑　樹也、北川　雅敏
- Organizer
  第45回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07569
[Presentation] TGFβにより誘導される長鎖ノンコーディングRNAの網羅的解析とその機能2022
- Author(s)
  酒井　聡、太田　幸佑、大畑　樹也、北川　雅敏
- Organizer
  第95回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07569
[Presentation] メスES細胞では両X染色体の活性化により相同組換え効率が減少している2021
- Author(s)
  田村友香、大畑樹也、丹伊田浩行、酒井聡、内田千晴、増本一真、加藤文度、Anton Wuts、北川雅敏
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19404
[Presentation] ストレス誘導性分子TRB3によるインターロイキン2の転写制御機構の解析2012
- Author(s)
  杉山和弥, 西仲駿, 伊藤友香, 井上靖道, 酒井聡, 小野嵜菊夫, 林秀敏
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] CYP3A4タンパク質の発現制御2011
- Author(s)
  森本真宗, 新開慈子, 伊藤友香, 酒井聡, 水谷隆治, 林秀敏
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ストレスセンサータンパク質TRB3によるIL-2転写制御機構の解析2011
- Author(s)
  杉山和弥, 西仲駿, 伊藤友香, 井上靖道, 酒井聡, 小野嵜菊夫, 林秀敏
- Organizer
  フォーラム2011:衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGFβによるUGT1A1の転写調節機構の解析2011
- Author(s)
  石井陽子, 中平桂子, 石戸谷その, 伊藤友香, 酒井聡, 水谷隆治, 林秀敏
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ストレスセンサータンパク質TRB3とTGF-βシグナルのクロストーク2011
- Author(s)
  牛山小百合, 井手佑子, 吉井由比子, 酒井聡, 伊藤友香, 大岡伸通, 小野嵜菊夫, 井上靖道, 林秀敏
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] 薬物代謝酵素UGT1A1タンパク質の安定性制御2011
- Author(s)
  石戸谷その, 伊藤友香, 酒井聡, 水谷隆治, 林秀敏
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] Regulation of FoxO1 activity by TRB12011
- Author(s)
  Y. Noguchi, W. Kojima, S. Sakai, Y. Itoh, Y. Inoue, H. Hayashi
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] Regulation of Cdc25A expression by pseudokinase, TRB12010
- Author(s)
  S.Sakai, H.Niida, M.Kitagawa, K.Onozaki, M.Nakanishi, H.Hayashi
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TRB1による糖新生制御分子FoxO1の転写活性増強作用2010
- Author(s)
  小島和香, 酒井聡, 伊藤友香, 林秀敏
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ストレス誘導性タンパクTRB3によるTGF-βシグナルの制御2010
- Author(s)
  牛山小百合, 井出佑子, 酒井聡, 伊藤友香, 大岡伸通, 小野嵜菊夫, 林秀敏
- Organizer
  第56回日本薬学会東海支部大会
- Place of Presentation
  岐阜
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TRB1によるCdc25Aの発現制御機構の解析2010
- Author(s)
  酒井聡, 大岡伸通, 北川雅., 中西真, 小野嵜菊夫, 林秀敏
- Organizer
  第33回日本分子生物学会年会・第83回生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGF-βによる白色脂肪細胞の脂肪滴消失に伴った遺伝子発現変化2010
- Author(s)
  楽恰, 井上万由美, 野口祐美子, 伊藤友香, 酒井聡, 小野嵜菊夫, 斉藤昌之, 林秀敏
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] Establishment of human TRB3 transgenic mice.2010
- Author(s)
  Y.Sakai, K.Fukamachi, M.Futakuchi, H.Tsuda, M.Suzui, H.Hayashi
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] Establishment of human TRB3 transgenic mice2010
- Author(s)
  Y. Sakai, K. Fukamachi, M. Futakuchi, H. Tsuda, M. Suzui, H. Hayashi
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ストレス誘導性pseudokinase TRB3のヘルパーT細胞分化に及ぼす影響2010
- Author(s)
  松平都和, 西仲駿, 森田陽子, 酒井聡, 伊藤友香, 林秀敏
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ハンチントン病関連遺伝子HAP1の機能解析2010
- Author(s)
  藤井拓夫, 酒井聡, 戸田洋平, 伊藤友香, 篠田晃, 林秀敏
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2010
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] pseudokinase TRB1によるCdc25Aの発現制御機構の解析2010
- Author(s)
  酒井聡, 大岡伸通, 北川雅敏, 中西真, 小野嵜菊夫, 林秀敏
- Organizer
  第74回日本生化学会中部支部例会
- Place of Presentation
  名古屋
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] BMPシグナル伝達分子Smad1の発現制御機構の解析2010
- Author(s)
  岩井俊樹, 伊藤友香, 酒井聡, 高橋佑輔, 井上靖道, 小野嵜菊夫, 林秀敏
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2010
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] 小胞体ストレス誘導性細胞死におけるpseudokinase TRB3の役割2009
- Author(s)
  中田佳宏, 酒井聡, 大岡伸通, 小野嵜菊夫, 林秀敏
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] 小胞体ストレス誘導性細胞死における pseudokinase TRB3の役割2009
- Author(s)
  中田佳宏, 酒井聡, 大岡伸通, 小野嵜菊夫, 林秀敏
- Organizer
  日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ユビキチンリガーゼAPC/C^<Cdh1>による pseudokinase TRB3の発現制御機構の解明2009
- Author(s)
  酒井聡, 大岡伸通, 北川雅敏, 中西真, 小野嵜菊夫, 林秀敏
- Organizer
  日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ストレス誘導性タンパク質TRB3によるTGF-βシグナルの制御2009
- Author(s)
  牛山小百合, 井手佑子, 酒井聡, 伊藤友香, 大岡伸道, 小野嵜菊夫, 林秀敏
- Organizer
  次世代を担う若手ファーマ・バイオフォーラム2009
- Place of Presentation
  名古屋
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21590067

1. Kitagawa Masatoshi (50294971)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. 大畑樹也 (80616459)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 丹伊田浩行 (20336671)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. HAYASHI Hidetoshi (80198853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
5. ITOH Yuka (40454326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
6. 松本雅記 (60380531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 内田千晴 (60223567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKAI Satoshi 酒井 聡

Sakai Satoshi 酒井 聡

Research Projects

Research Products

Co-Researchers

シグナル依存的な遺伝子発現制御機構の特異性と多様性を担う長鎖ncRNAの同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the malignant transformation mechanism of female tumors mediated by both X-chromosome activation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell fate control by lncRNA regulating genetic specificities of epigenetic factors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of development of malignant female cancers associated with X-chromosome reactivation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of HBV replication and liver cancer malignant progression by a novel lncRNA ELIT-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Crosstalk between stress and cytokine signaling in metabolic syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of tumor suppressor FHIT is regulated by the LINC00173-SNAIL axis in human lung adenocarcinoma.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] APOBEC3B expression is promoted by lincNMR collaborating with TGF-β-Smad pathway2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Homologous recombination is reduced in female embryonic stem cells by two active X chromosomes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anaphase promoting complex/cyclosome-Cdh1 mediates the ubiquitination and degradation of TRB3.2010

Author(s)

Journal Title

Data Source

[Journal Article] Dual mode of regulation of Cdc25A protein by TRB32010

Author(s)

Journal Title

Data Source

[Journal Article] Anaphase promoting complex/cyclosome-Cdh1 mediates the ubiquitination and degradation of TRB32010

Author(s)

Journal Title

Data Source

[Journal Article] Dual mode of regulation of Cdc25A protein by TRB32010

Author(s)

Journal Title

Data Source

[Journal Article] Anaphase promoting complex/cyclosome-Cdh1 mediates the ubiquitination and degradation of TRB32010

Author(s)

Journal Title

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[Journal Article] Dual mode of regulation of Cdc25A protein by TRB3.2010

Author(s)

Journal Title

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SAKAI Satoshi 酒井聡

Sakai Satoshi 酒井聡