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Ishigame Teruhide  石亀 輝英

ORCIDConnect your ORCID iD *help
Researcher Number 50583358
Other IDs
Affiliation (Current) 2025: 福島県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2023: 福島県立医科大学, 医学部, 講師
2016 – 2020: 福島県立医科大学, 医学部, 助教
2017: 福島県立医科大学, 医学部, その他
2016: 福島県立医科大学, 医学部, 博士研究員
Review Section/Research Field
Principal Investigator
Tumor diagnostics
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords
Principal Investigator
リンパ節転移 / 胃癌 / 消化器癌 / マイクロRNA
Except Principal Investigator
肝細胞スフェロイド / 3D培養 / 肝再生 / 3次元骨格 / 細胞間接着 / 肝組織由来スフェロイド … More / 皮下移植 / 核内受容体 / 異常リン酸化 / LRH1 / 膵癌 / 肝癌 / リコンビナントペプチド / 細胞シート / スフェロイド / シート技術 / 肝細胞分離 / 肝組織 / 3D培養 / 複合型肝細胞シート / 肝スフェロイド / 肝細胞 / 創薬 / 多能性幹細胞 / 大腸上皮細胞 / 疾患モデル / 家族性腫瘍 / APC / 家族性大腸ポリポーシス / 一塩基置換 / MEN2B / ゲノム編集 / 大腸ガン / ポリープ / 遺伝性疾患 / 創薬モデル / 分化 / iPS細胞 / FAP / 家族性大腸腺腫症 Less
  • Research Projects

    (5 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (15 People)
  •  肝組織由来スフェロイドを用いた肝オルガノイドの開発とその微小環境分子機構の解明

    • Principal Investigator
      丸橋 繁
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Fukushima Medical University
  •  肝癌と膵癌における核内受容体LRH1異常リン酸化の解明

    • Principal Investigator
      西間木 淳
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Fukushima Medical University
  •  Research on the Development of Composite Hepatocyte Sheets Using Liver Tissue-Derived Spheroids (LTOSs)

    • Principal Investigator
      MARUBASHI Shigeru
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Fukushima Medical University
  •  Personalized cancer management based on microRNA biomarkersPrincipal Investigator

    • Principal Investigator
      Ishigame Teruhide
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Fukushima Medical University
  •  FAP

    • Principal Investigator
      Nakamura Izumi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Fukushima Medical University

All 2023 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Aberrant phosphorylation of human LRH1 at serine 510 is predictable of hepatocellular carcinoma recurrence2023

    • Author(s)
      Nishimagi Atsushi、Kobayashi Makoto、Sugimoto Kotaro、Kofunato Yasuhide、Sato Naoya、Haga Junichiro、Ishigame Teruhide、Kimura Takashi、Kenjo Akira、Kobayashi Yasuyuki、Hashimoto Yuko、Marubashi Shigeru、Chiba Hideki
    • Journal Title

      Clinical and Experimental Medicine

      Volume: 23 Issue: 8 Pages: 4985-4995

    • DOI

      10.1007/s10238-023-01098-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08896, KAKENHI-PROJECT-23K08716, KAKENHI-PROJECT-21K06950, KAKENHI-PROJECT-23K27394
  • [Journal Article] microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L12019

    • Author(s)
      Ashizawa Mai、Okayama Hirokazu、Ishigame Teruhide、Thar Min Aung Kyi、Saito Katsuharu、Ujiie Daisuke、Murakami Yuko、Kikuchi Tomohiro、Nakayama Yuko、Noda Masaru、Tada Takeshi、Endo Hisahito、Fujita Shotaro、Sakamoto Wataru、Saito Motonobu、Saze Zenichiro、Momma Tomoyuki、Ohki Shinji、Mimura Kosaku、Kono Koji
    • Journal Title

      Molecular Cancer Research

      Volume: Epub ahead of print Issue: 6 Pages: 1403-1413

    • DOI

      10.1158/1541-7786.mcr-18-0831

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07146, KAKENHI-PROJECT-16K19946, KAKENHI-PROJECT-17K10643, KAKENHI-PROJECT-18K08652, KAKENHI-PROJECT-18K08712, KAKENHI-PROJECT-19K09151, KAKENHI-PROJECT-19K09180, KAKENHI-PROJECT-16K10511
  • [Journal Article] Clinical significance of soluble intercellular adhesion molecule-1 and interleukin-6 in patients with extrahepatic cholangiocarcinoma2017

    • Author(s)
      Shimura T, Shibata M, Gonda K, Kofunato Y, Okada R, Ishigame T, Kimura T, Kenjo A, Marubashi S, Kono K, Takenoshita S
    • Journal Title

      Journal of Investigative Surgery

      Volume: 印刷中 Issue: 6 Pages: 475-482

    • DOI

      10.1080/08941939.2017.1358310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10605, KAKENHI-PROJECT-16K07146
  • [Journal Article] ミスマッチ修復機構欠損を有する大腸癌におけるMicroRNAによるPD-L1制御機構2017

    • Author(s)
      芦澤舞、岡山洋和、Aung Kyi Thar Min、野田勝、青砥慶太、中島隆宏、石亀輝英、三村耕作、河野浩二
    • Journal Title

      癌と化学療法

      Volume: 44 Pages: 889-891

    • Data Source
      KAKENHI-PROJECT-16K07146
  • [Presentation] 肝癌における核内受容体LRH1異常リン酸化の解明2023

    • Author(s)
      西間木淳,杉本幸太郎,小林信,小船戸康英,月田茂之,武藤亮,佐藤直哉,芳賀淳一郎,石亀輝英,木村隆,見城明,千葉英樹,丸橋繁
    • Organizer
      第123回日本外科学会
    • Data Source
      KAKENHI-PROJECT-22K08896
  • [Presentation] 胃癌患者における腫瘍内CD15/CD8陽性細胞比の臨床的意義2018

    • Author(s)
      渡邊 淳一郎, 木村 隆, 武藤 亮, 佐藤 直哉, 小船戸 康英, 石亀 輝英, 岡田 良, 見城 明, 志村 龍男, 河野 浩二, 丸橋 繁
    • Organizer
      日本外科学会定期学術集会 118回
    • Data Source
      KAKENHI-PROJECT-16K07146
  • [Presentation] Identification of microRNAs that target PD-L1 in mismatch repair-deficient colorectal cancer2018

    • Author(s)
      Ashizawa M, Okayama H, Ishigame T, Mimura K, Kono K
    • Organizer
      ASCO-SITC CLINICAL IMMUNO-ONCOLOGY SYMPOSIUM
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07146
  • [Presentation] Identification of microRNAs that target PD-L1 in mismatch repair-deficient colorectal cancer2018

    • Author(s)
      芦澤舞,岡山洋和,石亀輝英,Thar Min Aung Kyi,氏家大輔,村上祐子,菊池智宏,野田勝,青砥慶太,中島隆宏,早瀬傑,坂本渉,藤田正太郎,遠藤久仁,齋藤元伸,門馬智之,佐瀬善一郎,三村耕作,大木進司,丸橋繁,河野浩二
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-16K07146
  • [Presentation] ミスマッチ修復機構欠損を有する大腸癌におけるmicroRNAによるPD-L1調整機構2017

    • Author(s)
      芦澤 舞,岡山 洋和,Min Aung Kyi Thar,野田 勝,青砥 慶太,中島 隆宏,石亀 輝英,円谷 彰,丸橋 繁,河野 浩二
    • Organizer
      第72回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-16K07146
  • [Presentation] 脱フコシル化抗体を用いたADCCの検討2017

    • Author(s)
      中島 隆宏,河野 浩二,芦澤 舞,千田 峻,野田 勝,青砥 慶太,立花 和之進,岡山 洋和,早瀬 傑,坂本 渉,石亀 輝英,齋藤 元伸,志村 龍男,大竹 徹,竹之下 誠一
    • Organizer
      第117回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-16K07146
  • 1.  MARUBASHI Shigeru (20362725)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  竹之下 誠一 (10167489)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  清水 裕史 (70553709)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  佐藤 直哉 (90622332)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  小船戸 康英 (70583425)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  Nakamura Izumi (80423804)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  岡山 洋和 (20583397)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  千田 峻 (40769642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  野田 勝 (50769643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  横内 裕二 (60252227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  武藤 亮 (10791478)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  鈴志野 聖子 (20816376)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  西間木 淳 (50867497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  杉本 幸太郎 (40791009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  志村 龍男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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