Ishigame Teruhide 石亀輝英

Researcher Number	50583358
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 福島県立医科大学, 医学部, 講師 2016 – 2020: 福島県立医科大学, 医学部, 助教 2017: 福島県立医科大学, 医学部, その他 2016: 福島県立医科大学, 医学部, 博士研究員
Review Section/Research Field	Principal Investigator Tumor diagnostics Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords	Principal Investigator リンパ節転移 / 胃癌 / 消化器癌 / マイクロRNA Except Principal Investigator 肝細胞スフェロイド / 3D培養 / 肝再生 / ３次元骨格 / 細胞間接着 / 肝組織由来スフェロイド … More / 皮下移植 / 核内受容体 / 異常リン酸化 / LRH1 / 膵癌 / 肝癌 / リコンビナントペプチド / 細胞シート / スフェロイド / シート技術 / 肝細胞分離 / 肝組織 / ３D培養 / 複合型肝細胞シート / 肝スフェロイド / 肝細胞 / 創薬 / 多能性幹細胞 / 大腸上皮細胞 / 疾患モデル / 家族性腫瘍 / APC / 家族性大腸ポリポーシス / 一塩基置換 / MEN2B / ゲノム編集 / 大腸ガン / ポリープ / 遺伝性疾患 / 創薬モデル / 分化 / iPS細胞 / FAP / 家族性大腸腺腫症 Less

肝組織由来スフェロイドを用いた肝オルガノイドの開発とその微小環境分子機構の解明
- Principal Investigator
  
  丸橋繁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
肝癌と膵癌における核内受容体LRH1異常リン酸化の解明
- Principal Investigator
  
  西間木淳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
Research on the Development of Composite Hepatocyte Sheets Using Liver Tissue-Derived Spheroids (LTOSs)
- Principal Investigator
  
  MARUBASHI Shigeru
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
Personalized cancer management based on microRNA biomarkersPrincipal Investigator
- Principal Investigator
  
  Ishigame Teruhide
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Fukushima Medical University
FAP
- Principal Investigator
  
  Nakamura Izumi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukushima Medical University

All 2023 2019 2018 2017

All Journal Article Presentation

[Journal Article] Aberrant phosphorylation of human LRH1 at serine 510 is predictable of hepatocellular carcinoma recurrence2023
- Author(s)
  Nishimagi Atsushi、Kobayashi Makoto、Sugimoto Kotaro、Kofunato Yasuhide、Sato Naoya、Haga Junichiro、Ishigame Teruhide、Kimura Takashi、Kenjo Akira、Kobayashi Yasuyuki、Hashimoto Yuko、Marubashi Shigeru、Chiba Hideki
- Journal Title
  
  Clinical and Experimental Medicine
  
  Volume: 23 Issue: 8 Pages: 4985-4995
- DOI
  10.1007/s10238-023-01098-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08896, KAKENHI-PROJECT-23K08716, KAKENHI-PROJECT-21K06950, KAKENHI-PROJECT-23K27394
[Journal Article] microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L12019
- Author(s)
  Ashizawa Mai、Okayama Hirokazu、Ishigame Teruhide、Thar Min Aung Kyi、Saito Katsuharu、Ujiie Daisuke、Murakami Yuko、Kikuchi Tomohiro、Nakayama Yuko、Noda Masaru、Tada Takeshi、Endo Hisahito、Fujita Shotaro、Sakamoto Wataru、Saito Motonobu、Saze Zenichiro、Momma Tomoyuki、Ohki Shinji、Mimura Kosaku、Kono Koji
- Journal Title
  
  Molecular Cancer Research
  
  Volume: Epub ahead of print Issue: 6 Pages: 1403-1413
- DOI
  10.1158/1541-7786.mcr-18-0831
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07146, KAKENHI-PROJECT-16K19946, KAKENHI-PROJECT-17K10643, KAKENHI-PROJECT-18K08652, KAKENHI-PROJECT-18K08712, KAKENHI-PROJECT-19K09151, KAKENHI-PROJECT-19K09180, KAKENHI-PROJECT-16K10511
[Journal Article] Clinical significance of soluble intercellular adhesion molecule-1 and interleukin-6 in patients with extrahepatic cholangiocarcinoma2017
- Author(s)
  Shimura T, Shibata M, Gonda K, Kofunato Y, Okada R, Ishigame T, Kimura T, Kenjo A, Marubashi S, Kono K, Takenoshita S
- Journal Title
  
  Journal of Investigative Surgery
  
  Volume: 印刷中 Issue: 6 Pages: 475-482
- DOI
  10.1080/08941939.2017.1358310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10605, KAKENHI-PROJECT-16K07146
[Journal Article] ミスマッチ修復機構欠損を有する大腸癌におけるMicroRNAによるPD-L1制御機構2017
- Author(s)
  芦澤舞、岡山洋和、Aung Kyi Thar Min、野田勝、青砥慶太、中島隆宏、石亀輝英、三村耕作、河野浩二
- Journal Title
  
  癌と化学療法
  
  Volume: 44 Pages: 889-891
- Data Source
  KAKENHI-PROJECT-16K07146
[Presentation] 肝癌における核内受容体LRH1異常リン酸化の解明2023
- Author(s)
  西間木淳，杉本幸太郎，小林信，小船戸康英，月田茂之，武藤亮，佐藤直哉，芳賀淳一郎，石亀輝英，木村隆，見城明，千葉英樹，丸橋繁
- Organizer
  第123回日本外科学会
- Data Source
  KAKENHI-PROJECT-22K08896
[Presentation] 胃癌患者における腫瘍内CD15/CD8陽性細胞比の臨床的意義2018
- Author(s)
  渡邊淳一郎, 木村隆, 武藤亮, 佐藤直哉, 小船戸康英, 石亀輝英, 岡田良, 見城明, 志村龍男, 河野浩二, 丸橋繁
- Organizer
  日本外科学会定期学術集会 118回
- Data Source
  KAKENHI-PROJECT-16K07146
[Presentation] Identification of microRNAs that target PD-L1 in mismatch repair-deficient colorectal cancer2018
- Author(s)
  Ashizawa M, Okayama H, Ishigame T, Mimura K, Kono K
- Organizer
  ASCO-SITC CLINICAL IMMUNO-ONCOLOGY SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07146
[Presentation] Identification of microRNAs that target PD-L1 in mismatch repair-deficient colorectal cancer2018
- Author(s)
  芦澤舞,岡山洋和,石亀輝英,Thar Min Aung Kyi,氏家大輔,村上祐子,菊池智宏,野田勝,青砥慶太,中島隆宏,早瀬傑,坂本渉,藤田正太郎,遠藤久仁,齋藤元伸,門馬智之,佐瀬善一郎,三村耕作,大木進司,丸橋繁,河野浩二
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K07146
[Presentation] ミスマッチ修復機構欠損を有する大腸癌におけるmicroRNAによるPD-L1調整機構2017
- Author(s)
  芦澤舞,岡山洋和,Min Aung Kyi Thar,野田勝,青砥慶太,中島隆宏,石亀輝英,円谷彰,丸橋繁,河野浩二
- Organizer
  第72回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K07146
[Presentation] 脱フコシル化抗体を用いたADCCの検討2017
- Author(s)
  中島隆宏,河野浩二,芦澤舞,千田峻,野田勝,青砥慶太,立花和之進,岡山洋和,早瀬傑,坂本渉,石亀輝英,齋藤元伸,志村龍男,大竹徹,竹之下誠一
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K07146

1. MARUBASHI Shigeru (20362725)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. 竹之下誠一 (10167489)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 清水裕史 (70553709)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 佐藤直哉 (90622332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 小船戸康英 (70583425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. Nakamura Izumi (80423804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岡山洋和 (20583397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 千田峻 (40769642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 野田勝 (50769643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 横内裕二 (60252227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 武藤亮 (10791478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 鈴志野聖子 (20816376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 西間木淳 (50867497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 杉本幸太郎 (40791009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 志村龍男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishigame Teruhide 石亀 輝英

Research Projects

Research Products

Co-Researchers

肝組織由来スフェロイドを用いた肝オルガノイドの開発とその微小環境分子機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝癌と膵癌における核内受容体LRH1異常リン酸化の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on the Development of Composite Hepatocyte Sheets Using Liver Tissue-Derived Spheroids (LTOSs)

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Personalized cancer management based on microRNA biomarkersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

FAP

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Aberrant phosphorylation of human LRH1 at serine 510 is predictable of hepatocellular carcinoma recurrence2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L12019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical significance of soluble intercellular adhesion molecule-1 and interleukin-6 in patients with extrahepatic cholangiocarcinoma2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ミスマッチ修復機構欠損を有する大腸癌におけるMicroRNAによるPD-L1制御機構2017

Author(s)

Journal Title

Data Source

[Presentation] 肝癌における核内受容体LRH1異常リン酸化の解明2023

Author(s)

Organizer

Data Source

[Presentation] 胃癌患者における腫瘍内CD15/CD8陽性細胞比の臨床的意義2018

Author(s)

Organizer

Data Source

[Presentation] Identification of microRNAs that target PD-L1 in mismatch repair-deficient colorectal cancer2018

Author(s)

Organizer

Data Source

[Presentation] Identification of microRNAs that target PD-L1 in mismatch repair-deficient colorectal cancer2018

Author(s)

Organizer

Data Source

[Presentation] ミスマッチ修復機構欠損を有する大腸癌におけるmicroRNAによるPD-L1調整機構2017

Author(s)

Organizer

Data Source

[Presentation] 脱フコシル化抗体を用いたADCCの検討2017

Author(s)

Organizer

Data Source

Ishigame Teruhide 石亀輝英