Kosumi Keisuke 小澄敬祐

… Alternative Names

KOSUMI Keisuke 小澄敬祐

Less

Researcher Number	50594884
Other IDs
Affiliation (Current)	2025: 熊本大学, 病院, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 熊本大学, 病院, 特任助教 2021: 熊本大学, 大学院生命科学研究部(医), 特定研究員 2019 – 2020: 熊本大学, 病院, 非常勤診療医師 2016 – 2018: 熊本大学, 医学部附属病院, 非常勤診療医師
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 50010:Tumor biology-related / Digestive surgery Except Principal Investigator Digestive surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 腫瘍免疫 / 消化器癌 / がん代謝 / マイクロバイオーム / 腫瘍微小環境 / バイオマーカー / Prognostic marker / Microbiome / Immunity / Radiogenomics … More / Esophageal cancer / 既存薬再開発 / ドラッグリポジショニング / ライフスタイル / 炎症 / 予後予測マーカー / 腸内細菌 / オートファジー / LSD1 / がん免疫 / エピジェネティクス … More Except Principal Investigator バイオマーカー / エピジェネティクス / がん代謝 / GAPPS / predictive marker / microbiome / immunity / cancer metabolism / epigenetic change / genetic change / 腫瘍免疫 / 消化器癌 / CCN family / epigenomic biomarker / NRF2 / 細胞外フラックスアナライザー / LINE-1 / LSD1 / esophageal cancer / epigenetics / Cancer metabolism / 食道癌 / C5aR / C5a / CAFs / 肝stellate cell / 大腸癌肝転移 / 肝星細胞 / C5a受容体 / 補体C5a Less

遺伝性胃癌臨床検体を用いた上部胃癌発癌メカニズムの解明と革新的治療法の確立
- Principal Investigator
  
  岩槻政晃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
消化器癌における腫瘍微小環境を標的としたRadiogenomics解析Principal Investigator
- Principal Investigator
  
  小澄敬祐
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Development of innovative therapies targeting the tumor microenvironment through drug repositioning.Principal Investigator
- Principal Investigator
  
  Kosumi Keisuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Development of the innovative new treatments targeting cancer metabolism utilizing large GI cancer cohortsPrincipal Investigator
- Principal Investigator
  
  KOSUMI Keisuke
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kumamoto University
Investigation of CCN family for development and drug resistance of gastrointestinal cancers
- Principal Investigator
  
  Nagai Youhei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
establishment of cancer treatment targeting C5a receptor and proteinase releaed by cancer cells
- Principal Investigator
  
  NITTA Hidetoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Functional analyses and developments of new therapies targeting LSD1 in gastrointestinal cancersPrincipal Investigator
- Principal Investigator
  
  KOSUMI Keisuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Epigenome analysis of cancer metabolism for the development of new biomarkers in esophageal cancer.
- Principal Investigator
  
  BABA Yoshifumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University

All 2024 2023 2021 2020 2019 2018 2017 2016 Other

All Journal Article Presentation

[Journal Article] Body Composition and Clinical Outcomes in Esophageal Cancer Patients Treated with Immune Checkpoint Inhibitors2024
- Author(s)
  Kosumi Keisuke、Baba Yoshifumi、Hara Yoshihiro、Wang Haolin、Nomoto Daichi、Toihata Tasuku、Ohuchi Mayuko、Harada Kazuto、Eto Kojiro、Ogawa Katsuhiro、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: Published online Issue: 6 Pages: 3839-3849
- DOI
  10.1245/s10434-024-15093-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08687, KAKENHI-PROJECT-21KK0153
[Journal Article] Intratumour Fusobacterium nucleatum and immune response to oesophageal cancer2023
- Author(s)
  Kosumi Keisuke、Baba Yoshifumi、Yamamura Kensuke、Nomoto Daichi、Okadome Kazuo、Yagi Taisuke、Toihata Tasuku、Kiyozumi Yuki、Harada Kazuto、Eto Kojiro、Sawayama Hiroshi、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  British Journal of Cancer
  
  Volume: 128 Issue: 6 Pages: 1155-1165
- DOI
  10.1038/s41416-022-02112-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08687, KAKENHI-PROJECT-20H03755, KAKENHI-PROJECT-21K16452, KAKENHI-PROJECT-23K24408, KAKENHI-PROJECT-23K15435, KAKENHI-PROJECT-22K08851, KAKENHI-PROJECT-21KK0153
[Journal Article] The Sulfur Microbial Diet and Risk of Colorectal Cancer by Molecular Subtypes and Intratumoral Microbial Species in Adult Men2021
- Author(s)
  Sikavi DR, Nguyen LH, Haruki K, Ugai T, Ma W, Wang DD, Thompson KN, Yan Y, Branck T, Wilkinson JE, Akimoto N, Zhong R, Lau MC, Mima K, Kosumi K, Morikawa T, Rimm EB, Garrett WS, Izard J, Cao Y, Song M, Huttenhower C, Ogino S, Chan AT.
- Journal Title
  
  Clinical and Translational Gastroenterology
  
  Volume: 12 Issue: 8 Pages: e00338-e00338
- DOI
  10.14309/ctg.0000000000000338
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17658, KAKENHI-PROJECT-21K08687, KAKENHI-PROJECT-21K08805
[Journal Article] Response to the Comment on “Genomic Alteration and Immunity-Implications in Esophageal Cancer”2021
- Author(s)
  Kosumi Keisuke、Baba Yoshifumi、Baba Hideo
- Journal Title
  
  Annals of Surgery
  
  Volume: 274 Issue: 6 Pages: e905-e906
- DOI
  10.1097/sla.0000000000004942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08687
[Journal Article] Patient Age and Long-term Survival in Colorectal Cancer Patients Who Undergo Emergency Surgery2021
- Author(s)
  KOSUMI KEISUKE、MIMA KOSUKE、MORITO ATSUSHI、YUMOTO SHINSEI、MATSUMOTO TAKASHI、INOUE MITSUHIRO、MIZUMOTO TAKAO、KUBOTA TATSUO、MIYANARI NOBUTOMO、BABA HIDEO
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 2 Pages: 1069-1076
- DOI
  10.21873/anticanres.14864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17658, KAKENHI-PROJECT-19K16750
[Journal Article] The microbiome, genetics, and gastrointestinal neoplasms: the evolving field of molecular pathological epidemiology to analyze the tumor?immune?microbiome interaction2020
- Author(s)
  Mima Kosuke、Kosumi Keisuke、Baba Yoshifumi、Hamada Tsuyoshi、Baba Hideo、Ogino Shuji
- Journal Title
  
  Human Genetics
  
  Volume: － Issue: 5 Pages: 725-746
- DOI
  10.1007/s00439-020-02235-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17658, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-19K16750
[Journal Article] Association of autophagy status with amount of Fusobacterium nucleatum in colorectal cancer2020
- Author(s)
  Haruki K, Kosumi K, Hamada T, Twombly TS, Väyrynen JP, et al.
- Journal Title
  
  The Journal of Pathology
  
  Volume: 250 Issue: 4 Pages: 397-408
- DOI
  10.1002/path.5381
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16750, KAKENHI-PROJECT-17KK0195, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-17H05094, KAKENHI-PROJECT-18K19586
[Journal Article] Significance of long-term surveillance for branch-duct intraductal papillary mucinous neoplasms from the perspective of molecular pathological epidemiology2020
- Author(s)
  Kosumi Keisuke、Hayashi Hiromitsu、Baba Hideo
- Journal Title
  
  Annals of Translational Medicine
  
  Volume: 8 Issue: 15 Pages: 977-977
- DOI
  10.21037/atm-20-2206
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16750
[Journal Article] An integrated analysis of lymphocytic reaction, tumour molecular characteristics and patient survival in colorectal cancer2020
- Author(s)
  Haruki K, Kosumi K (Co-first), Li P, Arima K, Väyrynen JP, Lau MC, Twombly TS, Hamada T, Glickman JN, Fujiyoshi K, Chen Y, Du C, Guo C, Väyrynen SA, Dias Costa A, Song M, Chan AT, Meyerhardt JA, Nishihara R, Fuchs CS, Liu L, Zhang X, Wu K, Giannakis M, Nowak JA, Ogino S
- Journal Title
  
  British Journal of Cancer
  
  Volume: 122(9) Issue: 9 Pages: 1367-1377
- DOI
  10.1038/s41416-020-0780-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16750
[Journal Article] Frailty is an independent risk factor for recurrence and mortality after curative resection in patients with stage I-III colorectal cancer2020
- Author(s)
  Mima K, Kurashige J, Miyanari N, Morito A, Yumoto S, Matsumoto T, Kosumi K, Inoue M, Mizumoto T, Kubota T, Baba H
- Journal Title
  
  Ann Gastroenterol Surg
  
  Volume: - Issue: 4 Pages: 405-412
- DOI
  10.1002/ags3.12337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05094, KAKENHI-PROJECT-20K17658, KAKENHI-PROJECT-19K16750
[Journal Article] Metabolic Profiling of Formalin-Fixed Paraffin-Embedded Tissues Discriminates Normal Colon from Colorectal Cancer2020
- Author(s)
  Arima K, Lau MC, Zhao M, Haruki K, Kosumi K, Mima K, Gu M, Väyrynen JP, Twombly TS, Baba Y, Fujiyoshi K, Kishikawa J, Guo C, Baba H, Richards WG, Chan AT, Nishihara R, Meyerhardt JA, Nowak JA, Giannakis M, Fuchs CS, Ogino S
- Journal Title
  
  Molecular Cancer Research
  
  Volume: - Issue: 6 Pages: 883-890
- DOI
  10.1158/1541-7786.mcr-19-1091
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16750, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-17H05094, KAKENHI-PROJECT-17KK0195
[Journal Article] Morphological lymphocytic reaction, patient prognosis and?PD‐1 expression after surgical resection for oesophageal cancer2019
- Author(s)
  Baba Y.、Yagi T.、Kosumi K.、Okadome K.、Nomoto D.、Eto K.、Hiyoshi Y.、Nagai Y.、Ishimoto T.、Iwatsuki M.、Iwagami S.、Miyamoto Y.、Yoshida N.、Komohara Y.、Watanabe M.、Baba H.
- Journal Title
  
  BJS
  
  Volume: 106 Issue: 10 Pages: 1352-1361
- DOI
  10.1002/bjs.11301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16750, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-17K10596
[Journal Article] Clinical Importance of Mean Corpuscular Volume as a Prognostic Marker After Esophagectomy for Esophageal Cancer2018
- Author(s)
  Yoshida Naoya、Kosumi Keisuke、Tokunaga Ryuma、Baba Yoshifumi、Nagai Yohei、Miyamoto Yuji、Iwagami Shiro、Iwatsuki Masaaki、Hiyoshi Yukiharu、Ishimoto Takatsugu、Eto Kojiro、Imamura Yu、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Annals of Surgery
  
  Volume: 271 Issue: 3 Pages: 1-1
- DOI
  10.1097/sla.0000000000002971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-19K09076
[Journal Article] TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PD-L1) expression status and tumor-infiltrating lymphocytes in colorectal carcinomas.2018
- Author(s)
  Hamada T, Soong TR, Masugi Y, Kosumi K*, Nowak JA, da Silva A, Mu XJ, Twombly TS, Koh H, Yang J, Song M, Liu L, Gu M, Shi Y, Nosho K, Morikawa T, Inamura K, Shukla SA, Wu CJ, Garraway LA, Zhang X, Wu K, Meyerhardt JA, Chan AT, Glickman JN, Rodig SJ, Freeman GJ, Fuchs CS, Nishihara R, Giannakis M, Ogino S.
- Journal Title
  
  OncoImmunology.
  
  Volume: 21 Feb Issue: 7 Pages: e1442999-e1442999
- DOI
  10.1080/2162402x.2018.1442999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Pyloroplasty may reduce weight loss 1 year after esophagectomy.2018
- Author(s)
  Harada K, Yoshida N, Baba Y, Nakamura K, Kosumi K, Ishimoto T, Iwatsuki M, Miyamoto Y, Sakamoto Y, Ajani JA, Watanabe M, Baba H.
- Journal Title
  
  Dis Esophagus.
  
  Volume: Mar 1 Issue: 3
- DOI
  10.1093/dote/dox127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Minimally invasive esophagectomy may contribute to long-term respiratory function after esophagectomy for esophageal cancer.2018
- Author(s)
  Kosumi K, Yoshida N, Okadome K, Eto T, Kuroda D, Ohuchi M, Kiyozumi Y, Nakamura K, Izumi D, Tokunaga R, Harada K, Mima K, Sawayama H, Ishimoto T, Iwatsuki M, Baba Y, Miyamoto Y, Watanabe M, Baba H.
- Journal Title
  
  Dis Esophagus.
  
  Volume: Feb 9. Issue: 6
- DOI
  10.1093/dote/dox153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] The Prognostic Impact of Controlling Nutritional Status (CONUT) in Intrahepatic Cholangiocarcinoma Following Curative Hepatectomy: A Retrospective Single Institution Study.2018
- Author(s)
  Miyata T, Yamashita YI, Higashi T, Taki K, Izumi D, Kosumi K, Tokunaga R, Nakagawa S, Okabe H, Imai K, Hashimoto D, Chikamoto A, Baba H.
- Journal Title
  
  World J Surg.
  
  Volume: 42(4) Issue: 4 Pages: 1085-1091
- DOI
  10.1007/s00268-017-4214-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells.2017
- Author(s)
  Gu M, Nishihara R, Chen Y, Li W, Shi Y, Masugi Y, Hamada T, Kosumi K, Liu L, da Silva A, Nowak JA, Twombly T, Du C, Koh H, Li W, Meyerhardt JA, Wolpin BM, Giannakis M, Aguirre AJ, Bass AJ, Drew DA, Chan AT, Fuchs CS, Qian ZR, Ogino S.
- Journal Title
  
  Oncotarget.
  
  Volume: 8(50) Issue: 50 Pages: 87379-87389
- DOI
  10.18632/oncotarget.20972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Dietary glycemic and insulin scores and colorectal cancer survival by tumor molecular biomarkers.2017
- Author(s)
  Keum N, Yuan C, Nishihara R, Zoltick E, Hamada T, Martinez Fernandez A, Zhang X, Hanyuda A, Liu L, Kosumi K, Nowak JA, Jhun I, Soong TR, Morikawa T, Tabung FK, Qian ZR, Fuchs CS, Meyerhardt JA, Chan AT, Ng K, Ogino S, Giovannucci EL, Wu K.
- Journal Title
  
  Int J Cancer
  
  Volume: 140(12) Issue: 12 Pages: 2648-2656
- DOI
  10.1002/ijc.30683
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Preoperative controlling nutritional status (CONUT) is useful to estimate the prognosis after esophagectomy for esophageal cancer.2017
- Author(s)
  Yoshida N, Harada K, Baba Y, Kosumi K, Iwatsuki M, Kinoshita K, Nakamura K, Sakamoto Y, Miyamoto Y, Karashima R, Mima K, Sawayama H, Ohuchi M, Chikamoto A, Imamura Y, Watanabe M, Baba H
- Journal Title
  
  Langenbeck Archiv Surg
  
  Volume: 402(2) Issue: 2 Pages: 333-41
- DOI
  10.1007/s00423-017-1553-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19942, KAKENHI-PROJECT-16K19941
[Journal Article] Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.2017
- Author(s)
  Kosumi K, Masugi Y, Yang J, Qian ZR, Kim SA, Li W, Shi Y, da Silva A, Hamada T, Liu L, Gu M, Twombly TS, Cao Y, Barbie DA, Nosho K, Baba H, Garrett WS, Meyerhardt JA, Giovannucci EL, Chan AT, Fuchs CS, Ogino S, Nishihara R.
- Journal Title
  
  Oncoimmunology
  
  Volume: 6(3) Issue: 3 Pages: e1284720-e1284720
- DOI
  10.1080/2162402x.2017.1284720
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status.2017
- Author(s)
  Hamada T, Cao Y, Qian ZR, Masugi Y, Nowak JA, Yang J, Song M, Mima K, Kosumi K, Liu L, Shi Y, da Silva A, Gu M, Li W, Keum N, Zhang X, Wu K, Meyerhardt JA, Giovannucci EL, Giannakis M, Rodig SJ, Freeman GJ, Nevo D, Wang M, Chan AT, Fuchs CS, Nishihara R, Ogino S.
- Journal Title
  
  J Clin Oncol
  
  Volume: - Issue: 16 Pages: 1836-1844
- DOI
  10.1200/jco.2016.70.7547
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Cell Cycle Protein Expression in Neuroendocrine Tumors: Association of CDK4/CDK6, CCND1, and Phosphorylated Retinoblastoma Protein With Proliferative Index.2017
- Author(s)
  Shi Y, Qian ZR, Zhang S, Li W, Masugi Y, Li T, Chan JA, Yang J, Da Silva A, Gu M, Liu L, Hamada T, Kosumi K, Dutton T, Brais LK, Nishihara R, Fuchs CS, Ogino S, Kulke MH.
- Journal Title
  
  Pancreas.
  
  Volume: 46(10) Issue: 10 Pages: 1347-1353
- DOI
  10.1097/mpa.0000000000000944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Body mass index and risk of colorectal carcinoma subtypes classified by tumor differentiation status.2017
- Author(s)
  Hanyuda A, Cao Y, Hamada T, Nowak JA, Qian ZR, Masugi Y, da Silva A, Liu L, Kosumi K, Soong TR, Jhun I, Wu K, Zhang X, Song M, Meyerhardt JA, Chan AT, Fuchs CS, Giovannucci EL, Ogino S, Nishihara R.
- Journal Title
  
  Eur J Epidemiol.
  
  Volume: 32(5) Issue: 5 Pages: 393-407
- DOI
  10.1007/s10654-017-0254-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Tumor PDCD1LG2 (PD-L2) Expression and the Lymphocytic Reaction to Colorectal Cancer.2017
- Author(s)
  Masugi Y, Nishihara R, Hamada T, Song M, da Silva A, Kosumi K, Gu M, Shi Y, Li W, Liu L, Nevo D, Inamura K, Cao Y, Liao X, Nosho K, Chan AT, Giannakis M, Bass AJ, Hodi FS, Freeman GJ, Rodig SJ, Fuchs CS, Qian ZR, Nowak JA, Ogino S.
- Journal Title
  
  Cancer Immunol Res.
  
  Volume: 5(11) Pages: 1046-1055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Comparison of systemic inflammatory and nutritional scores in colorectal cancer patients who underwent potentially curative resection.2017
- Author(s)
  Tokunaga R, Sakamoto Y, Nakagawa S, Izumi D, Kosumi K, Taki K, Higashi T, Miyata T, Miyamoto Y, Yoshida N, Baba H.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: in press Issue: 4 Pages: 740-748
- DOI
  10.1007/s10147-017-1102-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462020, KAKENHI-PROJECT-17K10640, KAKENHI-PROJECT-16K19943, KAKENHI-PROJECT-16K19941
[Journal Article] Association Between Inflammatory Diet Pattern and Risk of Colorectal Carcinoma Subtypes Classified by Immune Responses to Tumor.2017
- Author(s)
  Liu L, Nishihara R, Qian ZR, Tabung FK, Nevo D, Zhang X, Song M, Cao Y, Mima K, Masugi Y, Shi Y, da Silva A, Twombly T, Gu M, Li W, Hamada T, Kosumi K, Inamura K, Nowak JA, Drew DA, Lochhead P, Nosho K, Wu K, Wang M, Garrett WS, Chan AT, Fuchs CS, Giovannucci EL, Ogino S.
- Journal Title
  
  Gastroenterology.
  
  Volume: 153(6) Issue: 6 Pages: 1517-1530.e14
- DOI
  10.1053/j.gastro.2017.08.045
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08679, KAKENHI-PROJECT-16K19941
[Journal Article] Monitoring sputum culture in resected esophageal cancer patients with preoperative treatment.2017
- Author(s)
  Kosumi K, Baba Y, Yamashita K, Ishimoto T, Nakamura K, Ohuchi M, Kiyozumi Y, Izumi D1, Tokunaga R, Harada K, Shigaki H, Kurashige J, Iwatsuki M, Sakamoto Y, Yoshida N, Watanabe M, Baba H
- Journal Title
  
  Dis Esophagus
  
  Volume: 30(12) Issue: 12 Pages: 1-9
- DOI
  10.1093/dote/dox092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19943, KAKENHI-PROJECT-16K19941
[Journal Article] LINE-1 methylation level and patient prognosis in pancreas cancer: pyrosequencing technology and literature review.2017
- Author(s)
  Yamamura K, Kosumi K, Baba Y, Harada K, Zhang X, Zhou L, Kitano Y, Arima K, Kaida T, Takeyama H, Higashi T, Imai K, Hashimoto D, Chikamoto A, Tan X, Baba H.
- Journal Title
  
  Surg Today
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium Nucleatum in Tumor Tissue.2017
- Author(s)
  Mehta RS, Nishihara R, Cao Y, Song M, Mima K, Qian ZR, Nowak JA, Kosumi K, Hamada T, Masugi Y, Bullman S, Drew DA, Kostic AD, Fung TT, Garrett WS, Huttenhower C, Wu K, Meyerhardt JA, Zhang X, Willett WC, Giovannucci EL, Fuchs CS, Chan AT, Ogino S.
- Journal Title
  
  JAMA Oncol.
  
  Volume: - Issue: 7 Pages: 921-921
- DOI
  10.1001/jamaoncol.2016.6374
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma2016
- Author(s)
  K. Nakamura, Y. Baba, K. Kosumi, K. Harada, H. Shigaki, K. Miyake, Y. Kiyozumi, M. Ohuchi, J. Kurashige, T. Ishimoto, M. Iwatsuki, Y. Sakamoto, N. Yoshida, M. Watanabe, M. Nakao, and H. Baba.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 36 Pages: 57821-57831
- DOI
  10.18632/oncotarget.11067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-16K19941
[Journal Article] KRAS, BRAF, PIK3CA Mutations and Patient Prognosis in 126 Pancreatic Cancers: Pyrosequencing Technology and Literature Review.2016
- Author(s)
  Zhou L, Baba Y, Kitano Y, Miyake K, Zhang X, Yamamura K, Kosumi K, Kaida T, Arima K, Taki K, Higashi T, Imai K, Hashimoto D, Yamashita Y, Chikamoto A, Beppu T, Tan X, Baba H.
- Journal Title
  
  Med Oncol
  
  Volume: 33(4) Issue: 4 Pages: 32-32
- DOI
  10.1007/s12032-016-0745-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861089, KAKENHI-PROJECT-16K19941
[Journal Article] Lysine-specific demethylase-1 contributes to malignant behavior by regulation of invasive activity and metabolic shift in esophageal cancer2016
- Author(s)
  Kosumi K, Baba Y, Sakamoto Y, Ishimoto T, Harada K, Nakamura K, Kurashige J, Hiyoshi Y, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Oki E, Watanabe M, Hino S, Nakao M, Baba H
- Journal Title
  
  Int J Cancer
  
  Volume: 138 Issue: 2 Pages: 428-39
- DOI
  10.1002/ijc.29714
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10122, KAKENHI-PLANNED-23116009, KAKENHI-PROJECT-25430178, KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-26713042, KAKENHI-PROJECT-15K15068
[Journal Article] Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location.2016
- Author(s)
  Mima K, Cao Y, Chan AT, Qian ZR, Nowak JA, Masugi Y, Shi Y, Song M, da Silva A, Gu M, Li W, Hamada T, Kosumi K, Hanyuda A, Liu L, Kostic AD, Giannakis M, Bullman S, Brennan CA, Milner DA, Baba H, Garraway LA, Meyerhardt JA, Garrett WS, Huttenhower C, Meyerson M, Giovannucci EL, Fuchs CS, Nishihara R, Ogino S.
- Journal Title
  
  Clin Transl Gastroenterol
  
  Volume: 7(11) Issue: 11 Pages: e200-e200
- DOI
  10.1038/ctg.2016.53
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19941
[Journal Article] Prognostic and clinical impact of PIK3CA mutation in gastric cancer: pyrosequencing technology and literature review.2016
- Author(s)
  Harada K, Baba Y, Shigaki H, Ishimoto T, Miyake K, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Kurashige J, Iwatsuki M, Miyamoto Y, Sakamoto Y, Yoshida N, Watanabe M, Baba H.
- Journal Title
  
  BMC Cancer.
  
  Volume: 16 Issue: 1 Pages: 400-400
- DOI
  10.1186/s12885-016-2422-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19941, KAKENHI-PROJECT-16K19943
[Presentation] 高齢化社会を念頭においた大腸癌Oncologic emergency手術例の検討2020
- Author(s)
  小澄敬祐, 森戸淳, 湯本信成, 松本嵩史, 美馬浩介, 井上光弘, 水元孝郎, 久保田竜生, 宮成信友, 馬場秀夫
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-19K16750
[Presentation] Oncologic emergencyを伴う大腸癌緊急手術症例におけるDICの臨床学的意義2020
- Author(s)
  小澄敬祐, 森戸淳, 湯本信成, 松本嵩史, 美馬浩介, 井上光弘, 水元孝郎, 久保田竜生, 宮成信友, 馬場秀夫
- Organizer
  第28回日本消化器関連学会週間JDDW
- Data Source
  KAKENHI-PROJECT-19K16750
[Presentation] 食道癌における腫瘍内Fusobacterium nucleatumと腫瘍免疫の関連解析2019
- Author(s)
  小澄敬祐, 馬場祥史, 山村謙介, 野元大地, 岡留一雄, 八木泰佑, 清住雄希, 江藤弘二郎, 日吉幸晴, 石本崇胤, 岩槻政晃, 長井洋平, 岩上志朗, 宮本裕士, 吉田直矢, 渡邊雅之, 馬場秀夫
- Organizer
  第27回日本消化器関連学会週間 JDDW. 2019
- Data Source
  KAKENHI-PROJECT-19K16750
[Presentation] Bifidobacterium Genus in Colorectal Carcinoma Tissue in relation to Tumor Characteristics and Patient Survival.2018
- Author(s)
  Borowsky J, Kosumi K*, Hamada T, Koh H, Bullman S, Twombly TS, Masugi Y, Liu L, da Silva A, Chen Y, Du C, Gu M, Li C, Li W, Liu H, Shi Y, Song M, Nosho K, Nowak JA, Nishihara R, Baba H, Zhang X, Wu K, Huttenhower C, Garrett WS, Meyerson M, Lennerz JK, Giannakis M, Chan AT, Meyerhardt JA, Fuchs CS, Ogino S.
- Organizer
  1.ASIP Annual Meeting at Experimental Biology 2018
- Data Source
  KAKENHI-PROJECT-16K19941
[Presentation] Bifidobacterium genus in colorectal carcinoma tissue in relation to tumor characteristics and patient survival.2018
- Author(s)
  Kosumi K, Hamada T, Koh H, Borowsky J, Bullman S, Twombly TS, Masugi Y, Liu L, da Silva A, Chen Y, Du C, Gu M, Li C, Li W, Liu H, Shi Y, Song M, Nosho K, Nowak JA, Nishihara R, Baba H, Zhang X, Wu K, Huttenhower C, Garrett WS, Meyerson M, Lennerz JK, Giannakis M, Chan AT, Meyerhardt JA, Fuchs CS, Ogino S
- Organizer
  The 4th International Molecular Pathological Epidemiology (MPE) Meeting.
- Data Source
  KAKENHI-PROJECT-16K19941
[Presentation] LINE-1メチル化レベルのprognostic biomarkerとしての意義 -CGH ，Expression arrayによるメカニズム解析-2016
- Author(s)
  馬場祥史、小澄敬祐、徳永竜馬、志垣博信、藏重淳二、岩槻政晃、坂本快郎、吉田直矢、馬場秀夫
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  アスティとくしま（徳島県）
- Data Source
  KAKENHI-PROJECT-26713042
[Presentation] 食道癌におけるがん代謝関連酵素“LSD1”発現の網羅的解析
- Author(s)
  小澄敬祐
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-26713042

1. BABA Yoshifumi (20599708)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
2. HARADA Kazuto (70608869)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. 石本崇胤 (00594889)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 岩槻政晃 (50452777)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NITTA Hidetoshi (90555749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMAMURA Kensuke (10816507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Nagai Youhei (30551254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 藏重淳二 (90594474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吉田直矢 (60467983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 宮本裕士 (80551259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 三森功士 (50322748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KITANO Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIMA Kosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
14. HASHIMOTO Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. SAKAMOTO Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. INAMURA Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. BABA Hideo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 澤山浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 中尾光善

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 渡邊雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 井田智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 徳永竜馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kosumi Keisuke 小澄 敬祐

KOSUMI Keisuke 小澄 敬祐

Research Projects

Research Products

Co-Researchers

遺伝性胃癌臨床検体を用いた上部胃癌発癌メカニズムの解明と革新的治療法の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

消化器癌における腫瘍微小環境を標的としたRadiogenomics解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of innovative therapies targeting the tumor microenvironment through drug repositioning.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the innovative new treatments targeting cancer metabolism utilizing large GI cancer cohortsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of CCN family for development and drug resistance of gastrointestinal cancers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

establishment of cancer treatment targeting C5a receptor and proteinase releaed by cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analyses and developments of new therapies targeting LSD1 in gastrointestinal cancersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epigenome analysis of cancer metabolism for the development of new biomarkers in esophageal cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Body Composition and Clinical Outcomes in Esophageal Cancer Patients Treated with Immune Checkpoint Inhibitors2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intratumour Fusobacterium nucleatum and immune response to oesophageal cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Sulfur Microbial Diet and Risk of Colorectal Cancer by Molecular Subtypes and Intratumoral Microbial Species in Adult Men2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response to the Comment on “Genomic Alteration and Immunity-Implications in Esophageal Cancer”2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Patient Age and Long-term Survival in Colorectal Cancer Patients Who Undergo Emergency Surgery2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The microbiome, genetics, and gastrointestinal neoplasms: the evolving field of molecular pathological epidemiology to analyze the tumor?immune?microbiome interaction2020

Author(s)

Kosumi Keisuke 小澄敬祐

KOSUMI Keisuke 小澄敬祐