Shimada Kazuyuki 島田和之

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SHIMADA Kazuyuki 島田和之

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Researcher Number	50631503
Other IDs	https://orcid.org/0000-0002-1075-9219
Affiliation (Current)	2025: 名古屋大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2016 – 2023: 名古屋大学, 医学部附属病院, 講師 2015: 名古屋大学, 高等研究院(医), 特任講師 2014 – 2015: 名古屋大学, 高等研究院, 特任講師 2013 – 2015: 名古屋大学, 学内共同利用施設等, 講師
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Hematology
Keywords	Principal Investigator 悪性リンパ腫 / 臓器指向性 / 微小環境 / がん関連線維芽細胞 / エクソソーム / 腫瘍微小環境 / 異種移植マウスモデル / ピリミジン拮抗薬 / 中枢神経病変 / ヒストン脱アセチル化阻害薬 / 癌 / 腫瘍関連線維芽細胞 / 節外臓器浸潤 … More Except Principal Investigator … More シグナル伝達 / トランスレーショナルリサーチ / 癌 / 標準治療 / 酸化ストレス / PDX / 悪性リンパ腫 / 微小環境 / 薬剤スクリーニング / 中鎖脂肪酸誘導体 / pyruvinium pamoate / STAT3/5阻害剤 / 分子標的剤 / FLT3阻害剤 Less

悪性リンパ腫のクローン解析による病変形成および治療抵抗性獲得機序の解明Principal Investigator
- Principal Investigator
  
  島田和之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University
Eludation of organ tropism from the diversity of malignant lymphoma and its application to novel treatmentPrincipal Investigator
- Principal Investigator
  
  Shimada Kazuyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University
Elucidation of interaction between lymphoma cells and tumor microenvironment involved in organ tropism and development of novel therapiesPrincipal Investigator
- Principal Investigator
  
  KAZUYUKI SHIMADA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Elucidation of a mechanism of organ tropism in malignant lymphoma to develop novel treatment for intractable extranodal involvementPrincipal Investigator
- Principal Investigator
  
  SHIMADA Kazuyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Translational research toward drug discovery of leukemia
- Principal Investigator
  
  NAOE Tomoki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Hospital Organization Nagoya Medical Center
Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells
- Principal Investigator
  
  NAOE TOMOKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  National Hospital Organization Nagoya Medical Center

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Patent

[Journal Article] Secondary central nervous system involvement in patients with diffuse large B-cell lymphoma treated with rituximab combined CHOP therapy ? a supplementary analysis of JCOG06012024
- Author(s)
  Shimada K、Ohmachi K、Machida R、Ota S、Itamura H、Tsujimura H、Takayama N、Shimada T、Kurosawa M、Tabayashi T、Shimoyama T、Ohshima K、Miyazaki K、Maruyama D、Kinoshita T、Ando K、Hotta T、Tsukasaki K、Nagai H
- Journal Title
  
  Annals of Hematology
  
  Volume: 103 Issue: 6 Pages: 2021-2031
- DOI
  10.1007/s00277-024-05620-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15327, KAKENHI-PROJECT-23K07810
[Journal Article] Analyzing the risk factors for disease progression within 2 years and histological transformation in patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone as first‐line treatment: A 15‐year follow‐up of patients with advanced follicular lymphoma in JCOG02032024
- Author(s)
  Watanabe Takashi、Matsuno Yoshihiro、Wakabayashi Masashi、Maruyama Dai、Yamamoto Kazuhito、Kubota Nobuko、Shimada Kazuyuki、Asagoe Kohsuke、Yamaguchi Motoko、Ando Kiyoshi、Ogura Michinori、Kuroda Junya、Suehiro Youko、Tsukasaki Kunihiro、Tobinai Kensei、Nagai Hirokazu
- Journal Title
  
  Hematological Oncology
  
  Volume: 42 Issue: 3
- DOI
  10.1002/hon.3272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07810
[Journal Article] R-CHOP treatment for patients with advanced follicular lymphoma: Over 15‐year follow‐up of JCOG02032023
- Author(s)
  Watanabe Takashi、Tobinai Kensei、Wakabayashi Masaki、Maruyama Dai、Yamamoto Kazuhito、Kubota Nobuko、Shimada Kazuyuki、Asagoe Kohsuke、Yamaguchi Motoko、Ando Kiyoshi、Ogura Michinori、Kuroda Junya、Suehiro Youko、Matsuno Yoshihiro、Tsukasaki Kunihiro、Nagai Hirokazu
- Journal Title
  
  British Journal of Haematology
  
  Volume: 204 Issue: 3 Pages: 849-860
- DOI
  10.1111/bjh.19213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07810
[Journal Article] Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice2023
- Author(s)
  Sahashi Satomi、Shimada Kazuyuki、Takagi Yusuke、Aoki Tomohiro、Kunou Shunsuke、Sakamoto Akihiko、Murase Atsushi、Furukawa Katsuya、Kagaya Yusuke、Yamaga Yusuke、Takai Mika、Tokuyama Kiyonobu、Shimada Satoko、Nakamura Shigeo、Kiyoi Hitoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 2 Pages: 221-230
- DOI
  10.1007/s12185-023-03604-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07810, KAKENHI-PROJECT-23K27624
[Journal Article] Long‐term outcomes and central nervous system relapse in extranodal natural killer/T‐cell lymphoma2022
- Author(s)
  Miyazaki K, Suzuki R, Oguchi M, Taguchi S, ..., Yamaguchi M
- Journal Title
  
  Hematol Oncol
  
  Volume: 40 Issue: 4 Pages: 667-677
- DOI
  10.1002/hon.2977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08731, KAKENHI-PROJECT-20K08751
[Journal Article] A phase 2 study of axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma in Japan: 1-year follow-up and biomarker analysis2022
- Author(s)
  Kato Koji、Fujii Nobuharu、Makita Shinichi、Goto Hideki、Kanda Junya、Shimada Kazuyuki、Akashi Koichi、Izutsu Koji、Teshima Takanori、Fukuda Natsuko、Sumitani Tokuhito、Nakamura Shota、Sumi Hiroyuki、Shimizu Shinji、Kakurai Yasuyuki、Yoshikawa Kenji、Tobinai Kensei、Usui Noriko、Hatake Kiyohiko
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 3 Pages: 409-420
- DOI
  10.1007/s12185-022-03494-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08479, KAKENHI-PROJECT-20K08751
[Journal Article] Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma in the Gastrointestinal Tract in the Modern Era2022
- Author(s)
  Ishikawa Eri、Nakamura Masanao、Satou Akira、Shimada Kazuyuki、Nakamura Shotaro
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 2 Pages: 446-446
- DOI
  10.3390/cancers14020446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08751
[Journal Article] Follicular T-cell lymphoma mimicking lymphocyte-rich classic Hodgkin lymphoma: a case report of a diagnostic pitfall2021
- Author(s)
  Sakakibara Ayako、Suzuki Yuka、Kato Harumi、Yamamoto Kazuhito、Sakata-Yanagimoto Mamiko、Ishikawa Yuichi、Furukawa Katsuya、Shimada Kazuyuki、Kohno Kei、Nakamura Shigeo、Satou Akira、Kato Seiichi
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 61 Issue: 2 Pages: 97-101
- DOI
  10.3960/jslrt.20052
- NAID
  130008049329
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08751
[Journal Article] Spacer Length Modification Facilitates Discrimination between Normal and Neoplastic Cells and Provides Clinically Relevant CD37 CAR T Cells2021
- Author(s)
  Okuno Shingo、Adachi Yoshitaka、Terakura Seitaro、Julamanee Jakrawadee、Sakai Toshiyasu、Umemura Koji、Miyao Kotaro、Goto Tatsunori、Murase Atsushi、Shimada Kazuyuki、Nishida Tetsuya、Murata Makoto、Kiyoi Hitoshi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 206 Issue: 12 Pages: 2862-2874
- DOI
  10.4049/jimmunol.2000768
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08751, KAKENHI-PROJECT-21K08387
[Journal Article] Diagnostic utility of programmed cell death ligand 1 (clone SP142) immunohistochemistry for malignant lymphoma and lymphoproliferative disorders: A brief review2021
- Author(s)
  Sakakibara Ayako、Kohno Kei、Ishikawa Eri、Suzuki Yuka、Tsuyuki Yuta、Shimada Satoko、Shimada Kazuyuki、Satou Akira、Takahara Taishi、Ohashi Akiko、Takahashi Emiko、Kato Seiichi、Nakamura Shigeo、Asano Naoko
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 61 Issue: 4 Pages: 182-191
- DOI
  10.3960/jslrt.21003
- NAID
  130008131970
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08751
[Journal Article] Frequent genetic alterations in immune checkpoint-related genes in intravascular large B-cell lymphoma2021
- Author(s)
  Shimada Kazuyuki、Yoshida Kenichi、Suzuki Yasuhiro、Iriyama Chisako、Inoue Yoshikage、Sanada Masashi、Kataoka Keisuke、Yuge Masaaki、Takagi Yusuke、Kusumoto Shigeru、Masaki Yasufumi、Ito Takahiko、Inagaki Yuichiro、Okamoto Akinao、Kuwatsuka Yachiyo、Nakatochi Masahiro、Shimada Satoko、Miyoshi Hiroaki et al.
- Journal Title
  
  Blood
  
  Volume: 137 Issue: 11 Pages: 1491-1502
- DOI
  10.1182/blood.2020007245
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08751, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-18K15402, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-21K16279
[Journal Article] Exosomes secreted from cancer-associated fibroblasts elicit anti-pyrimidine drug resistance through modulation of its transporter in malignant lymphoma.2021
- Author(s)
  Kunou S, Shimada K, Takai M, Sakamoto A, Aoki T, Hikita T, Kagaya Y, Iwamoto E, Sanada M, Shimada S, Hayakawa F, Oneyama C, Kiyoi H.
- Journal Title
  
  Oncogene
  
  Volume: 40 Issue: 23 Pages: 3989-4003
- DOI
  10.1038/s41388-021-01829-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03456, KAKENHI-PROJECT-20K08723, KAKENHI-PROJECT-20K08751
[Journal Article] Current status of diagnosis and treatment in diffuse large B-cell lymphoma2021
- Author(s)
  島田和之
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 62 Issue: 8 Pages: 1077-1084
- DOI
  10.11406/rinketsu.62.1077
- NAID
  130008086004
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08751
[Journal Article] The Positivity of Phosphorylated STAT3 Is a Novel Marker for Favorable Prognosis in Germinal Center B-Cell Type of Diffuse Large B-Cell Lymphoma2021
- Author(s)
  K. Morichika, K. Karube, S. Sakihama, R. Watanabe, M. Kawaki, Y. Nishi, S. Nakachi, S. Okamoto, T. Takahara, A. Satou, S. Shimada, K. Shimada, T. Tsuzuki, T. Fukushima, S. Morishima and H. Masuzaki
- Journal Title
  
  Am J Surg Pathol
  
  Volume: - Issue: 6 Pages: 832-840
- DOI
  10.1097/pas.0000000000001691
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11079, KAKENHI-PROJECT-18K15104, KAKENHI-PROJECT-20K08751, KAKENHI-PROJECT-20K08912, KAKENHI-PROJECT-19K17862, KAKENHI-PROJECT-20K16204
[Journal Article] 血管内大細胞型B細胞リンパ腫研究の現状と今後の展望2021
- Author(s)
  島田和之
- Journal Title
  
  臨床血液
  
  Volume: 62 Pages: 631-640
- NAID
  130008061915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08751
[Journal Article] Clinicopathologic Analysis of Primary Adrenal Diffuse Large B-Cell Lymphoma2021
- Author(s)
  Kawano Tasuku、Tsuyuki Yuta、Suzuki Yuka、Shimada Kazuyuki、Kato Seiichi、Takahara Taishi、Mori Mayuko、Nakaguro Masato、Sakakibara Ayako、Nakamura Shigeo、Satou Akira
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: 45 Issue: 12 Pages: 1606-1615
- DOI
  10.1097/pas.0000000000001809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08751
[Journal Article] Current progress and future perspectives of research on intravascular large B‐cell lymphoma2021
- Author(s)
  Shimada Kazuyuki、Kiyoi Hitoshi
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 10 Pages: 3953-3961
- DOI
  10.1111/cas.15091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08751
[Journal Article] Expression of programmed cell death ligand‐1 by immune cells in the microenvironment is a favorable prognostic factor for primary diffuse large B‐cell lymphoma of the central nervous system2020
- Author(s)
  Tsuyuki Yuta、Ishikawa Eri、Kohno Kei、Shimada Kazuyuki、Ohka Fumiharu、Suzuki Yuka、Mabuchi Seiyo、Satou Akira、Takahara Taishi、Kato Seiichi、Miyagi Shohei、Ozawa Hiroyuki、Kawano Tasuku、Takagi Yusuke、Hiraga Junji、Wakabayashi Toshihiko、Nakamura Shigeo
- Journal Title
  
  Neuropathology
  
  Volume: 41 Issue: 2 Pages: 99-108
- DOI
  10.1111/neup.12705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08751, KAKENHI-PROJECT-19K16597
[Journal Article] PD‐L1 expression on tumor or stromal cells of nodal cytotoxic T‐cell lymphoma: A clinicopathological study of 50 cases2020
- Author(s)
  Yamashita Daisuke、Shimada Kazuyuki、Kohno Kei、Kogure Yasunori、Kataoka Keisuke、Takahara Taishi、Suzuki Yuka、Satou Akira、Sakakibara Ayako、Nakamura Shigeo、Asano Naoko、Kato Seiichi
- Journal Title
  
  Pathology International
  
  Volume: 70 Issue: 8 Pages: 513-522
- DOI
  10.1111/pin.12950
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08751
[Journal Article] Prognostic impact of PD-L1 expression in primary gastric and intestinal diffuse large B-cell lymphoma2020
- Author(s)
  Eri Ishikawa, Masanao Nakamura, Kazuyuki Shimada, Tsutomu Tanaka, Akira Satou, Kei Kohno, Ayako Sakakibara, Kazuhiro Furukawa, Takeshi Yamamura, Ryoji Miyahara, Shigeo Nakamura, Seiichi Kato & Mitsuhiro Fujishiro
- Journal Title
  
  J Gastroenterol
  
  Volume: 55 Issue: 1 Pages: 39-50
- DOI
  10.1007/s00535-019-01616-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09922
[Journal Article] Reappraisal of Primary Epstein-Barr Virus (EBV)-positive Diffuse Large B-Cell Lymphoma of the Gastrointestinal Tract2020
- Author(s)
  Miyagi Shouhei、Ishikawa Eri、Nakamura Masanao、Shimada Kazuyuki、Yamamura Takeshi、Furukawa Kazuhiro、Tanaka Tsutomu、Mabuchi Seiyo、Tsuyuki Yuta、Kohno Kei、Sakakibara Ayako、Satou Akira、Kato Seiichi、Fujishiro Mitsuhiro、Nakamura Shigeo
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: 44 Issue: 9 Pages: 1173-1183
- DOI
  10.1097/pas.0000000000001499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08751, KAKENHI-PROJECT-19K16597
[Journal Article] Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): a multicentre, single-arm, phase 2 trial2020
- Author(s)
  Shimada K, Yamaguchi M, Atsuta Y, Kiyoi H, Suzuki R, Tokunaga T, Nakamura S, Kinoshita T
- Journal Title
  
  The Lancet Oncology
  
  Volume: 21 Issue: 4 Pages: 593-602
- DOI
  10.1016/s1470-2045(20)30059-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922
[Journal Article] PD‐L1 (SP142) expression in neoplastic cells predicts a poor prognosis for patients with intravascular large B‐cell lymphoma treated with rituximab‐based multi‐agent chemotherapy2020
- Author(s)
  Suzuki Yuka、Kohno Kei、Matsue Kosei、Sakakibara Ayako、Ishikawa Eri、Shimada Satoko、Shimada Kazuyuki、Mabuchi Seiyo、Takahara Taishi、Kato Seiichi、Nakamura Shigeo、Satou Akira
- Journal Title
  
  Cancer Medicine
  
  Volume: 9 Issue: 13 Pages: 4768-4776
- DOI
  10.1002/cam4.3104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08751, KAKENHI-PROJECT-18K15104
[Journal Article] Immune evasion-related extranodal large B-cell lymphoma: A report of six patients with neoplastic PD-L1-positive extranodal diffuse large B-cell lymphoma2019
- Author(s)
  Suzuki Yuka、Sakakibara Ayako、Shimada Kazuyuki、Shimada Satoko、Ishikawa Eri、Nakamura Shigeo、Kato Seiichi、Takahara Taishi、Asano Naoko、Satou Akira、Kohno Kei
- Journal Title
  
  Pathology International
  
  Volume: 69 Issue: 1 Pages: 13-20
- DOI
  10.1111/pin.12742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09922
[Journal Article] Methotrexate-associated lymphoproliferative disorders of T-cell phenotype: clinicopathological analysis of 28 cases2019
- Author(s)
  Satou A, Tabata T, Miyoshi H, Kohno K, Suzuki Y, Yamashita D, Shimada K, Kawasaki T, Sato Y, Yoshino T, Ohshima K, Takahara T, Tsuzuki T, Nakamura S
- Journal Title
  
  Mod Pathol
  
  Volume: in press Issue: 8 Pages: 1135-1146
- DOI
  10.1038/s41379-019-0264-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08654, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-18K15104
[Journal Article] Divergence and heterogeneity of neoplastic PD‐L1 expression: Two autopsy case reports of intravascular large B‐cell lymphoma2019
- Author(s)
  Sakakibara Ayako、Inagaki Yuichiro、Imaoka Eiki、Sakai Yu、Ito Masafumi、Ishikawa Eri、Shimada Satoko、Shimada Kazuyuki、Suzuki Yuka、Nakamura Shigeo、Satou Akira、Kohno Kei
- Journal Title
  
  Pathology International
  
  Volume: 69 Issue: 3 Pages: 148-154
- DOI
  10.1111/pin.12757
- NAID
  120006711437
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09922
[Journal Article] Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells.2019
- Author(s)
  Sakamoto A, Kunou S, Shimada K, Tsunoda M, Aoki T, Iriyama C, Tomita A, Nakamura S, Hayakawa F, Kiyoi H.
- Journal Title
  
  Cancer Sci
  
  Volume: 110 Issue: 1 Pages: 269-278
- DOI
  10.1111/cas.13873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-18H02835
[Journal Article] EBV status has prognostic implication among young patients with angioimmunoblastic T‐cell lymphoma2019
- Author(s)
  Eladl Ahmed E.、Shimada Kazuyuki、Suzuki Yuka、Takahara Taishi、Kato Seiichi、Kohno Kei、Elsayed Ahmed Ali、Wu Chun‐Chieh、Tokunaga Takashi、Kinoshita Tomohiro、Sakata‐Yanagimoto Mamiko、Nakamura Shigeo、Satou Akira
- Journal Title
  
  Cancer Medicine
  
  Volume: 9 Issue: 2 Pages: 678-688
- DOI
  10.1002/cam4.2742
- NAID
  120007127703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15104, KAKENHI-PROJECT-17K09922
[Journal Article] Reappraisal of nodal Epstein-Barr Virus-negative cytotoxic T-cell lymphoma: Identification of indolent CD5+ diseases2018
- Author(s)
  Yamashita Daisuke、Shimada Kazuyuki、Takata Katsuyoshi、Miyata-Takata Tomoko、Kohno Kei、Satou Akira、Sakakibara Ayako、Nakamura Shigeo、Asano Naoko、Kato Seiichi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 8 Pages: 2599-2610
- DOI
  10.1111/cas.13652
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09922
[Journal Article] Clinicopathological analysis of primary intestinal diffuse large B-cell lymphoma: Prognostic evaluation of CD5, PD-L1, and Epstein-Barr virus on tumor cells2018
- Author(s)
  Ishikawa Eri、Kato Seiichi、Shimada Kazuyuki、Tanaka Tsutomu、Suzuki Yuka、Satou Akira、Kohno Kei、Sakakibara Ayako、Yamamura Takeshi、Nakamura Masanao、Miyahara Ryoji、Goto Hidemi、Nakamura Shigeo、Hirooka Yoshiki
- Journal Title
  
  Cancer Medicine
  
  Volume: 7 Issue: 12 Pages: 6051-6063
- DOI
  10.1002/cam4.1875
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09922
[Journal Article] A prognostic model, including the EBV status of tumor cells, for?primary gastric diffuse large B-cell lymphoma in the rituximab era2018
- Author(s)
  Ishikawa Eri、Tanaka Tsutomu、Shimada Kazuyuki、Kohno Kei、Satou Akira、Eladl Ahmed E.、Sakakibara Ayako、Furukawa Kazuhiro、Funasaka Kohei、Miyahara Ryoji、Nakamura Masanao、Goto Hidemi、Nakamura Shigeo、Kato Seiichi、Hirooka Yoshiki
- Journal Title
  
  Cancer Medicine
  
  Volume: 7 Issue: 7 Pages: 3510-3520
- DOI
  10.1002/cam4.1595
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09922
[Journal Article] Autopsy case report of intravascular large B-cell lymphoma with neoplastic PD-L1 expression2018
- Author(s)
  Sakakibara A, Inagaki Y, Imaoka E, Ishikawa E, Shimada S, Shimada K, Suzuki Y, Nakamura S, Satou A, Kohno K.
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 58 Issue: 1 Pages: 32-35
- DOI
  10.3960/jslrt.17037
- NAID
  130006512990
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09922
[Journal Article] Biology and management of primary effusion lymphoma.2018
- Author(s)
  Shimada K, Hayakawa F, Kiyoi H
- Journal Title
  
  Blood
  
  Volume: 132 Issue: 18 Pages: 1879-1888
- DOI
  10.1182/blood-2018-03-791426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-18H02835
[Journal Article] Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism.2017
- Author(s)
  Aoki T, Shimada K, Sakamoto A, Sugimoto K, Morishita T, Kojima Y, Shimada S, Kato S, Iriyama C, Kuno S, Harada Y, Tomita A, Hayakawa F, Kiyoi H.
- Journal Title
  
  Oncotarget.
  
  Volume: 8 Issue: 8 Pages: 13085-13098
- DOI
  10.18632/oncotarget.14393
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860724, KAKENHI-PROJECT-15K09473, KAKENHI-PROJECT-15K09472
[Journal Article] Altered EZH2 splicing and expression is associated with impaired histone H3 lysine 27 tri-Methylation in myelodysplastic syndrome2017
- Author(s)
  Shirahata-Adachi Mizuho、Iriyama Chisako、Tomita Akihiro、Suzuki Yasuhiro、Shimada Kazuyuki、Kiyoi Hitoshi
- Journal Title
  
  Leuk Res
  
  Volume: 63 Pages: 90-97
- DOI
  10.1016/j.leukres.2017.10.015
- NAID
  120006473525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-15K09473
[Journal Article] YM155 induces apoptosis through proteasome-dependent degradation of MCL-1 in primary effusion lymphoma.2017
- Author(s)
  Kojima Y, Hayakawa F, Morishita T, Sugimoto K, Minamikawa Y, Iwase M, Yamamoto H, Hirano D, Imoto N, Shimada K, Okada S, Kiyoi H
- Journal Title
  
  Pharmacol Res.
  
  Volume: in press Pages: 242-251
- DOI
  10.1016/j.phrs.2017.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860724, KAKENHI-PROJECT-16K08742, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09922, KAKENHI-PROJECT-15K09472
[Journal Article] SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway.2016
- Author(s)
  2.Takagi Y, Shimada K*, Shimada S, Sakamoto A, Naoe T, Nakamura S, Hayakawa F, Tomita A, Kiyoi H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 9 Pages: 1270-1280
- DOI
  10.1111/cas.13001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860724, KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-15K09473, KAKENHI-PROJECT-26242049
[Journal Article] Development and analysis of patient derived xenograft mouse models in intravascular large B-cell lymphoma. Leukemia.2016
- Author(s)
  Shimada K, Shimada S, Sugimoto K, Nakatochi M, Suguro M, Hirakawa A, Hocking TD, Takeuchi I, Tokunaga T, Takagi Y, Sakamoto A, Aoki T, Naoe T, Nakamura S, Hayakawa F, Seto M, Tomita A, Kiyoi H
- Journal Title
  
  Leukemia
  
  Volume: in press Issue: 7 Pages: 1568-1579
- DOI
  10.1038/leu.2016.67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-26860724
[Journal Article] Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells2015
- Author(s)
  Sugimoto K, Hayakawa F, Shimada S, Morishita T, Shimada K, Katakai T, Tomita A, Kiyoi H, Naoe T
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 13054-13054
- DOI
  10.1038/srep13054
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09472, KAKENHI-PROJECT-15K09473, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-25670101, KAKENHI-PROJECT-25293218
[Journal Article] Target Antigen Density Governs the Efficacy of Anti-CD20-CD28-CD3 ζ Chimeric Antigen Receptor-Modified Effector CD8+ T Cells.2015
- Author(s)
  Watanabe K, Terakura S, Martens AC, van Meerten T, Uchiyama S, Imai M, Sakemura R, Goto T, Hanajiri R, Imahashi N, Shimada K, Tomita A, Kiyoi H, Nishida T, Naoe T, Murata M
- Journal Title
  
  J Immunol
  
  Volume: 194(3) Pages: 911-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670449
[Journal Article] Target Antigen Density Governs the Efficacy of Anti-CD20-CD28-CD3 ζ Chimeric Antigen Receptor-Modified Effector CD8+ T Cells.2015
- Author(s)
  Watanabe K, Terakura S, Martens AC, van Meerten T, Uchiyama S, Imai M, Sakemura R, Goto T, Hanajiri R, Imahashi N, Shimada K, Tomita A, Kiyoi H, Nishida T, Naoe T, Murata M
- Journal Title
  
  J Immunol
  
  Volume: 194(3) Pages: 911-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293218
[Journal Article] Efficacy of ofatumumab against rituximab-resistant B-CLL/SLL cells with low CD20 protein expression.2014
- Author(s)
  Shimada K, Tomita A, Saito S, Kiyoi H.
- Journal Title
  
  Br J Haematol
  
  Volume: 165 Issue: 3 Pages: 455-7
- DOI
  10.1111/bjh.12857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24591388, KAKENHI-PROJECT-25293218, KAKENHI-PROJECT-25670449
[Journal Article] Prognostic significance of pleural or pericardial effusion and the implication of optimal treatment in primary mediastinal large B-cell lymphoma: a multicenter retrospective study in Japan.2014
- Author(s)
  Aoki T, Izutsu K, Suzuki R, Nakaseko C, Arima H, Shimada K, Tomita A, Sasaki M, Takizawa J, Mitani K, Igarashi T, Maeda Y, Fukuhara N, Ishida F, Niitsu N, Ohmachi K, Takasaki H, Nakamura N, Kinoshita T, Nakamura S, Ogura M.
- Journal Title
  
  Haematologica
  
  Volume: 99(12) Issue: 12 Pages: 1817-25
- DOI
  10.3324/haematol.2014.111203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591388, KAKENHI-PROJECT-25293218, KAKENHI-PROJECT-25670449, KAKENHI-PROJECT-26870038
[Journal Article] De novo diffuse large B-cell lymphoma with a CD20 immunohistochemistry-positive and flow cytometry-negative phenotype: Molecular mechanisms and correlation with rituximab sensitivity.2014
- Author(s)
  Tokunaga T, Tomita A, Sugimoto K, Shimada K, Iriyama C, Hirose T, Shirahata-Adachi M, Suzuki Y, Mizuno H, Kiyoi H, Asano N, Nakamura S, Kinoshita T, Naoe T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 1 Pages: 35-43
- DOI
  10.1111/cas.12307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24591388, KAKENHI-PROJECT-25670449
[Patent] 血液関連疾患患者のリンパ節由来の間質細胞2015
- Inventor(s)
  清井仁、冨田章裕、早川文彦、島田和之、坂本明彦
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] 単一施設での初発B細胞リンパ腫に対するDA-EPOCH-R療法の後方視的検討2023
- Author(s)
  藤原慎二、島田和之、吉山聡一、山家佑介、古川勝也、佐藤貴彦、中島麻梨絵、葉名尻良、牛島洋子、石川裕一、寺倉精太郎、清井仁
- Organizer
  第63回日本リンパ網内系学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K07810
[Presentation] Next generation diagnosis and treatment of intravascular large B-cell lymphoma2023
- Author(s)
  Kazuyuki Shimada
- Organizer
  第63回日本リンパ網内系学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07810
[Presentation] Five-year results of a phase 2 study of CNS-oriented therapy with R-CHOP for untreated intravascular large B-cell lymphoma: Final analysis of the PRIMEUR-IVL study2023
- Author(s)
  Shimada K, Yamaguchi M, Kuwatsuka Y et al.
- Organizer
  17th International Conference on Malignant Lymphoma
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07810
[Presentation] The efficacy of BTK inhibitor in IVLBCL preclinical mouse models.2023
- Author(s)
  Takai, Mika; Shimada, Kazuyuki; Kiyoi, Hitoshi
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K07810
[Presentation] Cancer associated fibroblasts augment the effect of anti-CD20 antibodies therapy via the MCP-1 secretion2023
- Author(s)
  Yusuke Yagama, Kazuyuki Shimada, Mika Takai, Kastuya Frukawa, Yusuke Kagaya, Hitoshi Kiyoi
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07810
[Presentation] Five-year results of a phase 2 study for untreated intravascular large B-cell lymphoma2023
- Author(s)
  Shimada K, Yamaguchi M, Kuwatsuka Y et al.
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07810
[Presentation] Development and Efficacy of a Novel Bromodomain and Extraterminal Domain Degrader K-256 in MYC/BCL2-Related Lymphoma2023
- Author(s)
  Furukawa, Kastuya; Shimada, Kazuyuki; Esaki, Masahiro; Tanaka, Kentaro; Yamamoto, Keisuke; Mori, Kiyotoshi; Kiyoi, Hitoshi
- Organizer
  65th Annual Meeting of the American-Society-of-Hematology (ASH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07810
[Presentation] 当院における初発濾胞性リンパ腫患者の予後の変遷2023
- Author(s)
  山家佑介、島田和之、藤原慎二、吉山聡一、加賀谷祐介、佐藤貴彦、古川勝也、中島麻梨絵、葉名尻良、牛島洋子、石川裕一、寺倉精太郎、清井仁
- Organizer
  第63回日本リンパ網内系学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K07810
[Presentation] 再発・難治性DLBCL治療のパラダイムシフト2022
- Author(s)
  島田和之
- Organizer
  第62回日本リンパ網内系学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] IVLBCLに対するBTK阻害薬のpreclinical modelにおける有効性2022
- Author(s)
  高井美佳、島田和之、清井仁
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] リンパ形質細胞性リンパ腫／原発性マクログロブリン血症の治療2022
- Author(s)
  島田和之
- Organizer
  第47回日本骨髄腫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] Clinical Outcomes of Elderly Patients with Advanced-Stage Classic Hodgkin Lymphoma Who Received an ABVD Regimen: A Multi-Center Retrospective Study in Japan (HORIZON study)2021
- Author(s)
  Makita S, Kusumoto S, Maeshima-Miyagi A, Hashimoto H, Tsujimura H, Uchida T, Inoue H, Ohtsuka E, Kurosawa M, Takayama N, Negoro E, Suzuki Y, Kuroda J, Murayama K, Takahashi N, Shimada K, Okamoto M, Makita M, Iwasaki H, Yoshida M, Asano N, Tamaru J, Maruyama D, Yamaguchi M, Nagai H
- Organizer
  63rd ASH Annual Meeting and Exposition.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] びまん性大細胞型B細胞リンパ腫の治療戦略2021
- Author(s)
  島田和之
- Organizer
  第83回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] 血管内大細胞型B細胞リンパ腫～これまでの研究の到達点と今後の展望～2021
- Author(s)
  島田和之
- Organizer
  第95回日本病理学会近畿支部学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] Exosomes derived from cancer associated fibroblasts induce a resistance to histone deacetylase inhibitors in lymphoma.2020
- Author(s)
  加賀谷裕介、島田和之、久納俊祐、疋田智也、青木智広、坂本明彦、早川文彦、小根山千歳、清井仁.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] NDRG2はびまん性大細胞型B細胞リンパ腫の中枢神経病変において高発現を来す2020
- Author(s)
  村瀨篤史、島田和之、青木智広、真田昌、中杤昌弘、島田聡子、久納俊祐、中村栄男、清井仁
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] Current achievement of research and clinical practice in intravascular large B-cell lymphoma2020
- Author(s)
  島田和之
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08751
[Presentation] IVLBCL細胞の体外培養系の構築と新規治療薬探索の試み2019
- Author(s)
  高井美佳，島田和之，林一彦，和田優子，小境夕紀，渡邉隆司，鈴木敬，吉田憲司，大谷直明，清井仁
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] Favorable outcomes of newly diagnosed intravascular large B-cell lymphoma patients treated with R-CHOP combined with high-dose methotrexate plus intrathecal chemotherapy: Results from a multicenter phase 2 trial (PRIMEUR-IVL)2019
- Author(s)
  Shimada K, Yamaguchi M, Atsuta Y et al.
- Organizer
  61st ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] Resistance of pyrimidine analogs in primary lymphoma cells is induced by exosomes from cancer associated fibroblasts2019
- Author(s)
  久納俊祐、島田和之、疋田智也、坂本明彦、小根山千歳、清井仁
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] Exosomes Derived from Cancer Associated Fibroblasts Elicit Drug Resistance of B-cell Lymphoma Cells through Modulation of Drug Transporter2019
- Author(s)
  Shunsuke Kunou, Kazuyuki Shimada, Tomoya Hikita, Tomohiro Aoki,　Akihiko Sakamoto, Fumihiko Hayakawa, Chitose Oneyama, Hitoshi Kiyoi
- Organizer
  The 10th JSH International Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] Exosomes Derived from Cancer Associated Fibroblasts Elicit Survival and Drug Resistance of Primary Lymphoma Cells2018
- Author(s)
  Shunsuke Kunou, Kazuyuki Shimada, Tomoya Hikita, Tomohiro Aoki, Akihiko Sakamoto, Fumihiko Hayakawa, Chitose Oneyama and Hitoshi Kiyoi
- Organizer
  60th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] 腫瘍微小環境由来エクソソームによるリンパ腫細胞の生存および薬剤耐性化2018
- Author(s)
  久納俊祐、島田和之、疋田智也、坂本明彦、小根山千歳、早川文彦、清井仁
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] 腫瘍関連線維芽細胞より分泌されるエクソソームは抗アポトーシス作用を介してゲムシタビン耐性をもたらす2018
- Author(s)
  久納俊祐、島田和之、疋田智也、青木智広、坂本明彦、加藤規利、早川文彦、小根山千歳、清井仁
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] びまん性大細胞型B細胞リンパ腫の分子病態と治療2017
- Author(s)
  島田和之
- Organizer
  第79回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] Detection of Recurrent Genetic Mutations in Intravascular Large B-Cell Lymphoma By Comprehensive Genetic Analyses Using Peripheral Blood Circulating Cell-Free DNA2017
- Author(s)
  Tomita A, Shimada K, Yoshida K, Suzuki Y, Iriyama C, Sanada M, Yuge M, Takagi Y, Kusumoto S, Masaki Y, Ito T, Inagaki Y, Okamoto A, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Kiyoi H.
- Organizer
  The 59th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] A Novel Prognostic Model for Primary Gastric Diffuse Large B-Cell Lymphoma in the Rituximab Era, Integrating EBV Harboring on Tumor Cells2017
- Author(s)
  Ishikawa E, Tanaka T, Shimada K, Goto H, Nakamura S, Kato S.
- Organizer
  The 59th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] Exosome secreted by CAFs as an important player in lymphoma microenvironment2017
- Author(s)
  久納俊祐、島田和之、青木智広、坂本明彦、加藤規利、石川裕一、清井仁
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09922
[Presentation] Emetine Elicits Apoptosis of Intractable B-Cell Lymphoma Cells with MYC Rearrangement through Inhibition of Glycolytic Metabolism2016
- Author(s)
  Aoki T, Shimada K, Sakamoto A, Sugimoto K, Morishita T, Kojima Y, Shimada S, Kato S, Iriyama C, Kuno S, Harada Y, Nakamura S, Tomita A, Hayakawa F, Kiyoi H.
- Organizer
  The 58th Annual Meeting and Exposition of the American Society of Hematology
- Place of Presentation
  San Diego (USA)
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] びまん性大細胞型B細胞リンパ腫における中枢神経浸潤予測因子としての骨髄浸潤の意義2016
- Author(s)
  青木智広、島田和之、入山智沙子、原田靖彦、牛島洋子、冨田章裕、清井仁
- Organizer
  第56回日本リンパ網内系学会総会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] 糖代謝の抑制がmyc陽性DLBCL腫瘍のアポトーシスを誘導する2016
- Author(s)
  青木智広、島田和之、坂本明彦、森下喬允、早川文彦、冨田章裕、清井仁
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] Discovering the novel drug targeting tumor-microenvironment for intractable lymphoma2016
- Author(s)
  Aoki T, Shimada K, Sakamoto A, Morishita T, Harada Y, Iriyama C, Hayakawa F, Tomita A, Kiyoi H.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] 異種移植マウスモデルを用いた血管内大細胞型B細胞リンパ腫の病態解析2016
- Author(s)
  島田和之
- Organizer
  第54回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-20
- Invited
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] Lymph node-associated stromal fibroblasts support B-cell lymphoma cells via the PI3K pathway.2015
- Author(s)
  坂本明彦、島田和之、片山幸、早川文彦、冨田章裕、清井仁.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] リンパ節関連の間質性線維芽細胞は液性因子を分泌することでB細胞リンパ腫細胞を支持する.2015
- Author(s)
  坂本明彦、島田和之、片山幸、早川文彦、冨田章裕、清井仁.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Lymph node-associated stromal fibroblasts as a potential source of humoral factors to support B-cell lymphoma cells via the phosphatidylinositol 3-kinase pathway2015
- Author(s)
  坂本明彦、島田和之、片山幸、早川文彦、冨田章裕、清井仁
- Organizer
  第44回国際実験血液学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Lymph node-associated stromal fibroblasts as a potential source of humoral factors to support B-cell lymphoma cells via the phosphatidylinositol 3-kinase pathway.2015
- Author(s)
  Sakamoto A, Shimada K, Katayama M, Hayakawa F, Tomita A, Kiyoi H.
- Organizer
  第44回国際実験血液学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] Lymph node-associated stromal fibroblasts support B-cell lymphoma cells via the PI3K pathway.2015
- Author(s)
  Sakamoto A, Shimada K, Katayama M, Hayakawa F, Tomita A, Kiyoi H.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] SPIB expression is a novel poor prognostic factor in DLBCL.2015
- Author(s)
  髙木雄介、島田和之、島田聡子、早川文彦、坂本明彦、中村栄男、冨田章裕、清井仁.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Lymph node-associated stromal fibroblasts as a potential souse of humoral factors to support B-cell lymphoma cells.2015
- Author(s)
  Sakamoto A, Shimada K, Katayama M, Hayakawa F, Tomita A, Kiyoi H.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] SPIB expression is a novel poor prognostic factor in DLBCL.2015
- Author(s)
  Takagi Y, Shimada K, Shimada S, Hayakawa F, Sakamoto A, Nakamura S, Tomita A, Kiyoi H.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] Analysis of rituximab resistance mechanism in CD20 positive B-cell lymphoma cells.2013
- Author(s)
  Kazuyuki Shimada, Akihiro Tomita, Takashi Tokunaga, Chisako Iriyama, Tomohiro Kinoshita, Hitoshi kiyoi, Cragg Mark, Tomoki Naoe.
- Organizer
  日本血液学会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 骨髄スメア標本とパイロシークエンス法を用いたB細胞性腫瘍におけるMYD88 L265P変異解析
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、山本絵里奈、金田典雄、清井仁
- Organizer
  第12回日本臨床腫瘍学会総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市博多区）
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-25670449
[Presentation] 末梢血cell-free DNAを用いたB細胞リンパ腫における遺伝子変異解析
- Author(s)
  鈴木康裕、冨田章裕、吉田健一、島田和之、入山智沙子、真田昌、白石友一、千葉健一、田中洋子、宮野悟、小川誠司、清井仁
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市西区）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25670449
[Presentation] Intravascular large B-cell lymphoma-from bench to bedside
- Author(s)
  島田和之
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25670449
[Presentation] Biological and genetic analyses of intravascular large B-cell lymphoma using xenograft mouse model.
- Author(s)
  島田和之、島田聡子、杉本慶樹、早川文彦、片山幸、平川晃弘、中村栄男、瀬戸加大、直江知樹、冨田章裕、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Intravascular large B-cell lymphoma-from bench to bedside
- Author(s)
  島田和之
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 末梢血遊離DNAを用いたB細胞リンパ腫における遺伝子変異解析
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、清井仁、et al
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25670449
[Presentation] Biological and genetic analyses of intravascular large B-cell lymphoma using xenograft mouse model
- Author(s)
  Shimada K,Shimada S,Sugimoto K,Hayakawa F,Katayama M,Hirakawa A,Nakamura S,Seto M,Naoe T,Tomita A,Kiyoi H.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府、大阪市）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] 骨髄スメア標本とパイロシークエンス法を用いたB細胞性腫瘍におけるMYD88 L265P変異解析
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、山本絵里奈、金田典雄、清井仁
- Organizer
  第12回日本臨床腫瘍学会総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市博多区）
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] 末梢血cell-free DNAを用いたB細胞リンパ腫における遺伝子変異解析
- Author(s)
  鈴木康裕、冨田章裕、吉田健一、島田和之、入山智沙子、真田昌、白石友一、千葉健一、田中洋子、宮野悟、小川誠司、清井仁
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市西区）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Utilization of Peripheral Blood Cell-free DNA for Genetic Analyses in MDS
- Author(s)
  Yasuhiro Suzuki, Akihiro Tomita, Chisako Iriyama, Kazuyuki Shimada, Hitoshi Kiyoi
- Organizer
  第35回国際血液学会議
- Place of Presentation
  China National Convention Center（北京、中国）
- Year and Date
  2014-09-04 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Intravascular large B-cell lymphoma-from bench to bedside
- Author(s)
  Shimada K
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府、大阪市）
- Year and Date
  2014-10-31 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi-Scid IL2Rγnull Mouse Xenograft Model
- Author(s)
  Shimada K,Shimada S,Sugimoto K,Hayakawa F,Katayama M,Hirakawa A,Takagi Y, Nakamura S,Seto M,Naoe T,Tomita A,Kiyoi H.
- Organizer
  The 56th Annual Meeting of the American Society of Hematology.
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-12-05 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26860724
[Presentation] Biological and genetic analyses of intravascular large B-cell lymphoma using xenograft mouse model.
- Author(s)
  島田和之、島田聡子、杉本慶樹、早川文彦、片山幸、平川晃弘、中村栄男、瀬戸加大、直江知樹、冨田章裕、清井仁
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25670449
[Presentation] Utilization of Peripheral Blood Cell-free DNA for Genetic Analyses in MDS
- Author(s)
  Yasuhiro Suzuki, Akihiro Tomita, Chisako Iriyama, Kazuyuki Shimada, Hitoshi Kiyoi
- Organizer
  第35回国際血液学会議
- Place of Presentation
  China National Convention Center（北京、中国）
- Year and Date
  2014-09-04 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-25670449
[Presentation] Clinical and Molecular Significance of Peripheral Blood Cell-Free DNA in B-Cell Lymphomas for Detection of Genetic Mutations and Correlation with Disease Status
- Author(s)
  Yasuhiro Suzuki、Akihiro Tomita、 Kenichi Yoshida、Kazuyuki Shimada、 Chisako Iriyama、Masashi Sanada, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Seishi Ogawa, Hitoshi Kiyoi
- Organizer
  第56回米国血液学会
- Place of Presentation
  Moscone Center （サンフランシスコ、米国）
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi-Scid IL2R γnull Mouse Xenograft Model.
- Author(s)
  Kazuyuki Shimada, Satoko Shimada, Keiki Sugimoto, Fumihiko Hayakawa, Miyuki Katayama, Akihiro Hirakawa, Yusuke Takagi, Shigeo Nakamura, Masao Seto, Tomoki Naoe, Akihiro Tomita, Hitoshi Kiyoi
- Organizer
  第56回米国血液学会
- Place of Presentation
  Moscone Center （サンフランシスコ、米国）
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25670449
[Presentation] Clinical and Molecular Significance of Peripheral Blood Cell-Free DNA in B-Cell Lymphomas for Detection of Genetic Mutations and Correlation with Disease Status
- Author(s)
  Yasuhiro Suzuki、Akihiro Tomita、 Kenichi Yoshida、Kazuyuki Shimada、 Chisako Iriyama、Masashi Sanada, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Seishi Ogawa, Hitoshi Kiyoi
- Organizer
  第56回米国血液学会
- Place of Presentation
  Moscone Center （サンフランシスコ、米国）
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25670449
[Presentation] 末梢血遊離DNAを用いたB細胞リンパ腫における遺伝子変異解析
- Author(s)
  鈴木康裕、冨田章裕、入山智沙子、島田和之、清井仁・・・他
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25293218
[Presentation] Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi-Scid IL2R γnull Mouse Xenograft Model.
- Author(s)
  Kazuyuki Shimada, Satoko Shimada, Keiki Sugimoto, Fumihiko Hayakawa, Miyuki Katayama, Akihiro Hirakawa, Yusuke Takagi, Shigeo Nakamura, Masao Seto, Tomoki Naoe, Akihiro Tomita, Hitoshi Kiyoi
- Organizer
  第56回米国血液学会
- Place of Presentation
  Moscone Center （サンフランシスコ、米国）
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25293218

1. NAOE Tomoki (50217634)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. HAYAKAWA Fumihiko (30402580)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. TOMITA Akihiro (80378215)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
4. KIYOI Hitoshi (90314004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
5. AKAO Yukihiro (00222505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KATO Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. KAWASAKI Tomonori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. SUZUKI Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 鈴木律朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 山口素子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 板村英和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 小根山千歳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 益崎裕章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 岡本士毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 佐藤啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimada Kazuyuki 島田 和之

SHIMADA Kazuyuki 島田 和之

Research Projects

Research Products

Co-Researchers

悪性リンパ腫のクローン解析による病変形成および治療抵抗性獲得機序の解明Principal Investigator

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Eludation of organ tropism from the diversity of malignant lymphoma and its application to novel treatmentPrincipal Investigator

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Review Section

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Elucidation of interaction between lymphoma cells and tumor microenvironment involved in organ tropism and development of novel therapiesPrincipal Investigator

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Elucidation of a mechanism of organ tropism in malignant lymphoma to develop novel treatment for intractable extranodal involvementPrincipal Investigator

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Translational research toward drug discovery of leukemia

Principal Investigator

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Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells

Principal Investigator

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[Journal Article] Secondary central nervous system involvement in patients with diffuse large B-cell lymphoma treated with rituximab combined CHOP therapy ? a supplementary analysis of JCOG06012024

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[Journal Article] R-CHOP treatment for patients with advanced follicular lymphoma: Over 15‐year follow‐up of JCOG02032023

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[Journal Article] Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice2023

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[Journal Article] Long‐term outcomes and central nervous system relapse in extranodal natural killer/T‐cell lymphoma2022

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[Journal Article] A phase 2 study of axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma in Japan: 1-year follow-up and biomarker analysis2022

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[Journal Article] Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma in the Gastrointestinal Tract in the Modern Era2022

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[Journal Article] Follicular T-cell lymphoma mimicking lymphocyte-rich classic Hodgkin lymphoma: a case report of a diagnostic pitfall2021

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NAID

Shimada Kazuyuki 島田和之

SHIMADA Kazuyuki 島田和之