Muromachi Koichiro 室町幸一郎

… Alternative Names

MUROMACHI Koichiro 室町幸一郎

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Researcher Number	50637072
Other IDs
Affiliation (Current)	2025: 神奈川歯科大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help	2024: 神奈川歯科大学, 歯学部, 診療科准教授 2021 – 2023: 神奈川歯科大学, 歯学部, 講師 2019 – 2020: 神奈川歯科大学, 大学院歯学研究科, 講師 2016 – 2018: 神奈川歯科大学, 大学院歯学研究科, 助教 2014 – 2015: 神奈川歯科大学, 歯学研究科(研究院), 助教 2013: 日本大学, 松戸歯学部, 助手(専任扱) 2012: 日本大学, 歯学部, その他
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Conservative dentistry Except Principal Investigator Conservative dentistry
Keywords	Principal Investigator BMP-1 / 象牙質・歯髄複合体 / 修復象牙質 / 歯学 / 糖鎖 / 歯髄・象牙質複合体 / GBA1 / α2,6-sia / GCase / 質量分析 … More / レクチン / シアル酸 / 細胞・組織 / グライコーム / 歯髄 / CCN2/CTGF / 歯髄/象牙質複合体 / CTGF/CCN2 … More Except Principal Investigator 唾液分泌速度 / 唾液IgA 濃 / マウスピース / 唾液IgA / マウスガード / 分泌型IgA / T3NSS / 花粉症 / 口腔内マウスピース / 分泌型IgＡ / 粘膜免疫 Less

歯髄においてBMP-1-GBA1経路が細胞増殖とDNA複製に寄与する機構の解明Principal Investigator
- Principal Investigator
  
  室町幸一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Kanagawa Dental College
Identification of novel wound healing factors focusing on nuclear accumulation of GCase in human dental pulpPrincipal Investigator
- Principal Investigator
  
  MUROMACHI Koichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Kanagawa Dental College
Role of alfa2,6-sialylation of human dental pulp cellsPrincipal Investigator
- Principal Investigator
  
  MUROMACHI Koichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Kanagawa Dental College
The effect of salivary secretion with mouthguard use on seasonal allergic rhinitis symptom
- Principal Investigator
  
  Tani-Ishii Nobuyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Conservative dentistry
- Research Institution
  Kanagawa Dental College
Mechanisms of reparative dentin formation focusing on glycome-shift in human dental pulp cellsPrincipal Investigator
- Principal Investigator
  
  MUROMACHI Koichiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kanagawa Dental College
Protease activity-independent role of BMP-1 in reparative dentin formationPrincipal Investigator
- Principal Investigator
  
  MUROMACHI Koichiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kanagawa Dental College
Role of CTGF/CCN2 in reparative dentin formationPrincipal Investigator
- Principal Investigator
  
  MUROMACHI Koichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Conservative dentistry
- Research Institution
  Nihon University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] Cell Biological Assays for Measuring Odontogenic Activities of CCN Proteins (Chapter 23). Methods in Molecular Biology “CCN Proteins”2017
- Author(s)
  Koichiro MUROMACHI, Hiroshi SUGIYA, Nobuyuki TANI-ISHII
- Total Pages
  557
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-16K20469
[Journal Article] BMP-1-induced GBA1 nuclear accumulation provokes CCN2 mRNA expression via importin-β-mediated nucleocytoplasmic pathway2023
- Author(s)
  Koichiro Muromachi, Rei Nakano, Junko Fujita-Yoshigaki, Hiroshi Sugiya, Nobuyuki Tani-Ishii
- Journal Title
  
  Journal of Cell Communication and Signaling
  
  Volume: - Issue: 2 Pages: 263-274
- DOI
  10.1007/s12079-023-00740-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09882, KAKENHI-PROJECT-22K15002
[Journal Article] Regulation of PGE<sub>2</sub> production via CXCR4 by MIF in human pulpitis2020
- Author(s)
  神尾直人、渡邊昂洋、葉山朋美、深井譲滋、小峯千明、室町幸一郎、松島潔
- Journal Title
  
  The Journal of Japan Endodontic Association
  
  Volume: 41 Issue: 1 Pages: 22-30
- DOI
  10.20817/jeajournal.41.1_22
- NAID
  130007798505
- ISSN
  1347-8672, 2423-9429
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09587
[Journal Article] Delayed diagnosis of odontogenic infection: a lesson from altered mental status and abnormal breathing2018
- Author(s)
  Sawaoka Ai、Ito Toshiki、Yoshida Takayuki、Muromachi Koichiro、Sakai Tomoko、Hamada Kunio、Tani-Ishii Nobuyuki、Ito Akihide
- Journal Title
  
  Oxford Medical Case Reports
  
  Volume: 2018 Issue: 11 Pages: 359-361
- DOI
  10.1093/omcr/omy079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09587
[Journal Article] Kallikrein Promotes Inflammation in Human Dental Pulp Cells via Protease-Activated Receptor-1.2016
- Author(s)
  Hayama T, Kamio N, Okabe T, Muromachi K, Matsushima K.
- Journal Title
  
  J Cell Biochem
  
  Volume: 117 Issue: 7 Pages: 1522-8
- DOI
  10.1002/jcb.25437
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11131, KAKENHI-PROJECT-16K20469
[Journal Article] 専門医への道　症例報告2016
- Author(s)
  室町幸一郎
- Journal Title
  
  日本歯内療法学会雑誌
  
  Volume: 37 Pages: 45-48
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861609
[Journal Article] CCN2/CTGF expression via cellular uptake of BMP-1 is associated with reparative dentinogenesis2015
- Author(s)
  Koichiro MUROMACHI, Naoto KAMIO, Miwako MATSUKI-FUKUSHIMA, Hitoshi NISHIMURA, Nobuyuki TANI-ISHII, Hiroshi SUGIYA, Kiyoshi MATSUSHIMA
- Journal Title
  
  Oral Diseases
  
  Volume: 21 Issue: 6 Pages: 778-784
- DOI
  10.1111/odi.12347
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861609
[Journal Article] Metalloproteases and CCN2/CTGF in dentin-pulp complex repair2015
- Author(s)
  Koichiro MUROMACHI, Naoto KAMIO, Miwako MATSUKI-FUKUSHIMA, Takanori NARITA, Hitoshi NISHIMURA, Nobuyuki TANI-ISHII, Hiroshi SUGIYA, Kiyoshi MATSUSHIMA
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 57 Issue: 2 Pages: 86-90
- DOI
  10.1016/j.job.2014.12.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861609
[Journal Article] Plasmin-induced Cyclooxygenase-2 Expression via Calcineurin Activation in Human Dental Pulp Cells2014
- Author(s)
  神尾直人、室町幸一郎、葉山朋美、岡部達、神尾素代、諸橋利朗、松島潔
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 57 Issue: 5 Pages: 442-451
- DOI
  10.11471/shikahozon.57.442
- NAID
  130004716690
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861609
[Journal Article] Tumor necrosis factorαstimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells2012
- Author(s)
  Narita T, Muromachi K, Kamio N, Nakao S, Matsushima K, Hashizume H
- Journal Title
  
  Journal of Oral Science
  
  Volume: 54 Pages: 329-326
- NAID
  130003318541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890258
[Presentation] ヒト歯髄におけるBMP-1-GBA1経路の役割2023
- Author(s)
  室町幸一郎, 中野令, 吉垣純子, 杉谷博士, 石井信之
- Organizer
  第14回日本CCNファミリー研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09882
[Presentation] BMP-1はGCaseを介してMCM2の発現を調節しヒト歯髄培養細胞の増殖に関与する2023
- Author(s)
  室町幸一郎, 中野令, 吉垣純子, 杉谷博士, 石井信之
- Organizer
  日本歯科保存学会 2023年度春季学術大会（第158回）
- Data Source
  KAKENHI-PROJECT-21K09882
[Presentation] BMP-1-GCaseはヒト歯髄培養細胞においてMCM2の発現を調節し細胞増殖に関与する2022
- Author(s)
  室町幸一郎, 中野令, 吉垣純子, 杉谷博士, 石井信之
- Organizer
  第13回日本CCNファミリー研究会
- Data Source
  KAKENHI-PROJECT-21K09882
[Presentation] ヒト歯髄培養細胞におけるBMP-1を起点としたGCaseによるCCN2発現調節2021
- Author(s)
  室町幸一郎, 中野令, 吉垣純子, 杉谷博士, 石井信之
- Organizer
  第12回日本CCNファミリー研究会
- Data Source
  KAKENHI-PROJECT-21K09882
[Presentation] ヒト歯髄におけるBMP-1を起点としたGlcCeraseの細胞内局在と酵素活性の制御2020
- Author(s)
  室町幸一郎、中野令、吉垣純子、杉谷博士、石井信之
- Organizer
  日本歯科保存学会 2020年度春季学術大会（第152回）
- Data Source
  KAKENHI-PROJECT-18K09587
[Presentation] ヒト歯髄におけるglucosylceramidaseに対するBMP-1の役割2019
- Author(s)
  室町幸一郎、石井信之
- Organizer
  第11回日本CCNファミリー研究会
- Data Source
  KAKENHI-PROJECT-18K09587
[Presentation] 帯状疱疹との関連が疑われた歯髄炎の症例2019
- Author(s)
  室町幸一郎、石井信之
- Organizer
  第40回日本歯内療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09587
[Presentation] BMP-1によりグライコームシフトを生じる歯髄細胞膜タンパク質の同定2018
- Author(s)
  室町幸一郎、石井信之
- Organizer
  日本歯科保存学会　2018年度春季学術大会（第148回）
- Data Source
  KAKENHI-PROJECT-18K09587
[Presentation] 花粉症のアレルギー症状改善における唾液分泌に関する研究2018
- Author(s)
  石井信之、室町幸一郎、武藤徳子
- Organizer
  日本アレルギー学会、千葉、6月24日
- Data Source
  KAKENHI-PROJECT-16K15796
[Presentation] The Study on Salivary Secretion in Allergic Rhinitis Symptom Improvement2018
- Author(s)
  N. Tani-Ishii, K. Muromachi, N.Mutoh
- Organizer
  IADR, London, July 26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15796
[Presentation] A comprehensive analysis of the effects of BMP-1 on glyco-alteration in human dental pulp cells.2018
- Author(s)
  Koichiro MUROMACHI, Nobuyuki TANI-ISHII
- Organizer
  The 11th World Endodontic Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09587
[Presentation] ヒト歯髄においてBMP-1によりα2,6-シアル酸修飾が抑制されるタンパク質の同定2018
- Author(s)
  室町幸一郎、石井信之
- Organizer
  第10回日本CCNファミリー研究会
- Data Source
  KAKENHI-PROJECT-18K09587
[Presentation] マイクロスコープとCBCTを併用し歯髄を保存したOehlers 3型歯内歯の症例2018
- Author(s)
  室町幸一郎、武村幸彦、石井信之
- Organizer
  第39回日本歯内療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09587
[Presentation] 花粉症のアレルギー症状改善における歯科保存治療の応用2017
- Author(s)
  石井信之、毛塚　甫、三輪知志、下島かおり、室町幸一郎、鈴木二郎、武藤徳子
- Organizer
  第52回神奈川歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-16K15796
[Presentation] BMP-1によるヒト歯髄培養細胞のα2,6-シアル酸修飾の抑制2017
- Author(s)
  室町幸一郎、石井信之
- Organizer
  第９回　日本CCNファミリー研究会
- Data Source
  KAKENHI-PROJECT-16K20469
[Presentation] 根尖性歯周炎を伴う幼若永久歯に再生歯内療法を用いデンティンブリッジ様硬組織形成を認めた症例2017
- Author(s)
  室町幸一郎、石井信之
- Organizer
  第38回　日本歯内療法学会学術大会
- Data Source
  KAKENHI-PROJECT-16K20469
[Presentation] 花粉症のアレルギー性鼻炎症状改善における歯科保存治療の応用に関する研究2017
- Author(s)
  石井信之、毛塚　甫、三輪知志、下島かおり、室町幸一郎、武藤徳子、鈴木二郎
- Organizer
  第146回日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-16K15796
[Presentation] BMP-1によるヒト歯髄培養細胞の糖鎖修飾2016
- Author(s)
  室町幸一郎, 石井信之
- Organizer
  第８回日本CCNファミリー研究会
- Place of Presentation
  岡山大学
- Invited
- Data Source
  KAKENHI-PROJECT-16K20469
[Presentation] BMP-1によるヒト歯髄培養細胞のmucin様糖鎖修飾2016
- Author(s)
  室町幸一郎, 石井信之
- Organizer
  日本歯科保存学会　2016年度秋季学術大会（第145回）
- Place of Presentation
  キッセイ文化ホール（長野県松本文化会館）
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K20469
[Presentation] 歯内-歯周疾患（Simon I型）を生じた根未完成歯のApexificationにMineral Trioxide Aggregateを応用した症例2016
- Author(s)
  室町幸一郎, 鈴木二郎, 石井信之
- Organizer
  第37回日本歯内療法学会学術大会
- Place of Presentation
  ・ウインクあいち（愛知県産業労働センター）
- Year and Date
  2016-07-23
- Data Source
  KAKENHI-PROJECT-16K20469
[Presentation] BMP-1によるヒト歯髄細胞膜糖鎖の変化2015
- Author(s)
  室町幸一郎, 石井信之
- Organizer
  日本歯科保存学会　2015年度秋季学術大会（第143回）
- Place of Presentation
  文京シビックホール（東京都）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-26861609
[Presentation] ヒト歯髄培養細胞におけるLPSのNeuropsin発現に与える影響2015
- Author(s)
  神尾直人, 葉山朋美, 室町幸一郎, 五味博之, 喜多詰規雄, 上田幾大, 三浦孝司, 山浦賀弘, 松島潔
- Organizer
  日本歯科保存学会　2015年度秋季学術大会（第143回）
- Place of Presentation
  文京シビックホール（東京都）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-26861609
[Presentation] BMP-1 regulates CCN2 expression and cell surface glycosylation in human dental pulp2015
- Author(s)
  Koichiro MUROMACHI, Nobuyuki TANI-ISHII
- Organizer
  The 8th International Workshop On The CCN Family Of Genes
- Place of Presentation
  Westminster Hotel (Nice, FRANCE)
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861609
[Presentation] BMP-1 promotes CTGF/CCN2 expression independently of protease activity in human carious teeth2013
- Author(s)
  Koichiro MUROMACHI, Naoto KAMIO, Kiyoshi MATSUSHIMA
- Organizer
  The 9th World Endodontic Congress
- Place of Presentation
  Tokyo International Forum (Tokyo)
- Data Source
  KAKENHI-PROJECT-24890258
[Presentation] BMP-1 promotes CTGF/CCN2 expression independently of protease activity in human carious teeth2013
- Author(s)
  Muromachi K, Kamio N, Matsushima K
- Organizer
  IFEA The 9th World Endodontic Congress
- Place of Presentation
  Tokyo, JAPAN
- Data Source
  KAKENHI-PROJECT-24890258
[Presentation] PlasminによるCOX-2産生シグナルと細胞内カルシウムイオン濃度の変化2013
- Author(s)
  神尾直人,室町幸一郎,葉山朋美,松島潔
- Organizer
  日本歯科保存学会2013年度秋季学術大会(第139回)
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-24890258
[Presentation] BMP-1 promotes CTGF/CCN2 expression independently of protease activity in human carious teeth2013
- Author(s)
  室町　幸一郎
- Organizer
  The 9th World Endodontic Congress
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PROJECT-24890258
[Presentation] PlasminによるCOX-2産生シグナルと細胞内カルシウムイオン濃度の変化2013
- Author(s)
  神尾直人, 室町幸一郎, 葉山朋美, 松島潔
- Organizer
  日本歯科保存学会　2013年度秋季学術大会（第139回）
- Place of Presentation
  秋田県総合生活文化会館（アトリオン）（秋田県）
- Data Source
  KAKENHI-PROJECT-24890258
[Presentation] ヒト象牙質・歯髄複合体におけるメタロプロテアーゼとCTGF/CCN2発現2013
- Author(s)
  室町幸一郎,神尾直人,松島潔
- Organizer
  第55回歯科基礎医学会学術大会サテライトシンポジウム
- Place of Presentation
  岡山
- Year and Date
  2013-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-24890258
[Presentation] ヒト象牙質･歯髄複合体におけるメタロプロテアーゼとCTGF/CCN2発現
- Author(s)
  室町幸一郎, 神尾直人, 松島潔
- Organizer
  第５５回　歯科基礎医学会学術大会（サテライトシンポジウム）
- Place of Presentation
  岡山コンベンションセンター（岡山県）
- Invited
- Data Source
  KAKENHI-PROJECT-24890258
[Presentation] BMP-1-induced CCN2/CTGF expression is associated with reparative dentin formation
- Author(s)
  Koichiro MUROMACHI, Naoto KAMIO, Miwako MATSUKI-FUKUSHIMA, Hitoshi NISHIMURA, Nobuyuki TANI-ISHII, Hiroshi SUGIYA, Kiyoshi MATSUSHIMA
- Organizer
  IADR 93rd General Session and Exhibition
- Place of Presentation
  Hynes Convention Center, (Boston, Mass., USA)
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26861609
[Presentation] BMP-1はエンドサイトーシスを経てCCN2/CTGFの発現を促進し第三象牙質形成に関与する
- Author(s)
  室町幸一郎, 神尾直人, 松島潔, 石井信之
- Organizer
  日本歯科保存学会　2014年度秋季学術大会（第141回）
- Place of Presentation
  山形テルサ（山形県）
- Year and Date
  2014-10-30 – 2014-10-31
- Data Source
  KAKENHI-PROJECT-26861609

1. Tani-Ishii Nobuyuki (20163610)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. 伊藤寿樹 (00284753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 武藤徳子 (40510433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 吉垣純子 (40256904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 中野令 (60755619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KAMIO Naoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Muromachi Koichiro 室町 幸一郎

MUROMACHI Koichiro 室町 幸一郎

Research Projects

Research Products

Co-Researchers

歯髄においてBMP-1-GBA1経路が細胞増殖とDNA複製に寄与する機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel wound healing factors focusing on nuclear accumulation of GCase in human dental pulpPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

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Role of alfa2,6-sialylation of human dental pulp cellsPrincipal Investigator

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The effect of salivary secretion with mouthguard use on seasonal allergic rhinitis symptom

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Mechanisms of reparative dentin formation focusing on glycome-shift in human dental pulp cellsPrincipal Investigator

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Protease activity-independent role of BMP-1 in reparative dentin formationPrincipal Investigator

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Role of CTGF/CCN2 in reparative dentin formationPrincipal Investigator

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[Book] Cell Biological Assays for Measuring Odontogenic Activities of CCN Proteins (Chapter 23). Methods in Molecular Biology “CCN Proteins”2017

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[Journal Article] BMP-1-induced GBA1 nuclear accumulation provokes CCN2 mRNA expression via importin-β-mediated nucleocytoplasmic pathway2023

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[Journal Article] Regulation of PGE<sub>2</sub> production via CXCR4 by MIF in human pulpitis2020

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[Journal Article] Delayed diagnosis of odontogenic infection: a lesson from altered mental status and abnormal breathing2018

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[Journal Article] Kallikrein Promotes Inflammation in Human Dental Pulp Cells via Protease-Activated Receptor-1.2016

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[Journal Article] 専門医への道 症例報告2016

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[Journal Article] CCN2/CTGF expression via cellular uptake of BMP-1 is associated with reparative dentinogenesis2015

Muromachi Koichiro 室町幸一郎

MUROMACHI Koichiro 室町幸一郎

[Journal Article] 専門医への道　症例報告2016