kashiwagi korehito 柏木維人

… Alternative Names

Researcher Number	50722451
Affiliation (Current)	2021: 獨協医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2017 – 2021: 獨協医科大学, 医学部, 助教 2014 – 2016: 福島県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Human pathology Except Principal Investigator Basic Section 49020:Human pathology-related / Experimental pathology / Human pathology / Basic Section 48010:Anatomy-related / Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 癌 / 肺がん / クローディン / 細胞間接着 / 癌代謝 / 核内受容体 / 難治性癌 / がん代謝 / 難治性がん / 病理学 … More Except Principal Investigator 細胞間接着 / 神経内分泌肺癌 / 分化 / 再生医学 / 分化転換 / RB1遺伝子ファミリー / 増殖 / 肺癌発生 / 細胞接着 / 核内受容体 / エストロゲン受容体 / シグナル伝達 / がん / 子宮体癌 / 子宮体がん / 病理学 / タイト結合 / 子宮内膜癌 / クローディン / クロストーク / 細胞内シグナル / 内分泌顆粒, secretory granule / 分化制御 / 細胞内オルガネラ / 内分泌マーカー / 超微形態学的解析 / REST / MYT1L / 肺癌 / 腺癌 / 希少型 / 腫瘍発生 Less

Elucidation of molecular mechanism that endocrine secretory granule biogenesis
- Principal Investigator
  
  石井順
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Dokkyo Medical University
Molecular basis of tumorigenesis of pulmonary neuroendocrine cancer via REST and MYT1L
- Principal Investigator
  
  矢澤卓也
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Dokkyo Medical University
複数のクローディン分子連携による小細胞肺癌の悪性形質制御機構Principal Investigator
- Principal Investigator
  
  柏木維人
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Dokkyo Medical University
Molecular basis of tumorigenesis in pulmonary adenocarcinomas of rare histologic types
- Principal Investigator
  
  矢澤華子 (佐藤)
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Dokkyo Medical University
Molecular basis of neuroendocrine lung carcinogenesis in association with dysfunction of RB1-family proteins
- Principal Investigator
  
  矢澤卓也
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Dokkyo Medical University
The mechanism of malignant phenotype in small cell lung cancer enhanced by claudinsPrincipal Investigator
- Principal Investigator
  
  柏木維人
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Dokkyo Medical University
Promotion of cancer progression by aberrant cell adhesion signaling
- Principal Investigator
  
  Chiba Hideki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Fukushima Medical University
Developing novel treatment of refractory cancer by targeting Liver X Receptor and its metabolism related genePrincipal Investigator
- Principal Investigator
  
  Kashiwagi Korehito
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Dokkyo Medical University
  Fukushima Medical University
Development of a novel direct reprogramming method using cell adhesion signal
- Principal Investigator
  
  Chiba Hideki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Fukushima Medical University

All 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Cell adhesion signals regulate the nuclear receptor activity2019
- Author(s)
  Sugimoto Kotaro、Ichikawa-Tomikawa Naoki、Kashiwagi Korehito、Endo Chihiro、Tanaka Satoshi、Sawada Norimasa、Watabe Tetsuya、Higashi Tomohito、Chiba Hideki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Pages: 24600-24609
- DOI
  10.1073/pnas.1913346116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08699, KAKENHI-PROJECT-17K08766
[Journal Article] Expression of liver X receptors in normal and refractory carcinoma tissues of the human lung and pancreas2018
- Author(s)
  Korehito Kashiwagi, Mai Yanagida, Daiki Matsui, Mizuko Tanaka, Kotaro Sugimoto, Honglei Chen, Naoki Ichikawa-Tomikawa, Shigeru Marubashi, Hiroyuki Suzuki, Hideki Chiba
- Journal Title
  
  Histology and Histopathology
  
  Volume: 33 Pages: 497-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19083
[Journal Article] The liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression2015
- Author(s)
  Kaneko T, Kanno C, Ichikawa-Tomikawa N, Kashiwagi K, Yaginuma N, Ohkoshi C, Tanaka M, Sugino T, Imura T, Hasegawa H, Chiba H
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 33345-33357
- DOI
  10.18632/oncotarget.5428
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670191
[Presentation] REST/PROX1遺伝子発現変化はクロモグラニン高発現細胞を増加させる2020
- Author(s)
  宮澤公輔、辰田功顕、石井　順、矢澤華子、柏木維人、矢澤卓也
- Organizer
  第48回獨協医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] REST/PROX1遺伝子発現変化はクロモグラニン高発現細胞を増加させる2020
- Author(s)
  宮澤公輔、辰田功顕、村井　陸、石井　順、矢澤華子、柏木維人、岩本雅美、平松千恵、正和明哲、矢澤卓也
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] 硬化性肺上皮腫の遺伝子変異解析2019
- Author(s)
  太田昌幸、河村大輔、矢澤華子、柏木維人、石井順、矢澤卓也、石川俊平、吉野一郎、池田純一郎、中谷行雄
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] Liver X receptor (LXR) βは小細胞肺癌治療の新規標的分子になり得る2019
- Author(s)
  辰田功顕、宮澤公輔、柏木維人、矢澤華子、石井順、岩本雅美、正和明哲、太田昌幸、千葉英樹、矢澤卓也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] 小細胞肺癌細胞集団におけるDLK1陽性細胞は増殖に寄与する2019
- Author(s)
  石井順、矢澤華子、柏木維人、鈴木盛一朗、平松千恵、岩本雅美、太田昌幸、正和明哲、矢澤卓也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] 小細胞肺癌細胞集団におけるDLK1陽性細胞は増殖に寄与する2019
- Author(s)
  石井順、矢澤華子、柏木維人、鈴木清一朗、平松千恵、岩本雅美、太田昌幸、正和明哲、矢澤卓也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] 内分泌顆粒形成を制御する２遺伝子：PROX1およびREST2019
- Author(s)
  内藤美桜、原田慎也、石井順、矢澤華子、柏木維人、鈴木盛一朗、岩本雅美、正和明哲、太田昌幸、矢澤卓也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] RB1ファミリーの活性化が細胞増殖やEMTに及ぼす影響2019
- Author(s)
  正和明哲、矢澤卓也、矢澤華子、石井順、柏木維人、石井芳樹
- Organizer
  第59回日本呼吸器病学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] CDX2遺伝子導入による腸型肺腺癌細胞作製の試み2019
- Author(s)
  谷口有寿佳、坂口舞、江島一志、矢澤華子、石井順、柏木維人、平松千恵、正和明哲、太田昌幸、矢澤卓也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] POU3F4およびPOU4F2強制発現に伴い共通して活性化する転写因子HES5の制御による神経内分泌形質の減弱化2018
- Author(s)
  矢澤華子、柏木維人、石井順、平松千恵、菅間博、矢澤卓也
- Organizer
  第22回日本臨床内分泌病理学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06996
[Presentation] 細胞接着シグナルによる正常細胞機能とがん悪性形質の新規制御機構2018
- Author(s)
  杉本幸太郎，冨川直樹，柏木惟人，小島学，村上祐子，田中瑞子，東智仁，千葉英樹
- Organizer
  第107回日本病理学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08699
[Presentation] Mutual activation of Claudin-6 and Src family kinases triggers epithelial differentiation via RARγ phosphorylation2018
- Author(s)
  Kotaro Sugimoto, Naoki Ichikawa-Tomikawa, Korehito Kashiwagi, Tomohito Higashi, Hideki Chiba
- Organizer
  Joint Annual Meeting of JSDB 5st and JSCB 70th
- Invited
- Data Source
  KAKENHI-PROJECT-17K08699
[Presentation] タイト結合分子クローディン-6の発現は子宮内膜癌の予後不良因子である2017
- Author(s)
  小島学、杉本幸太郎、田中瑞子、柏木維人、齋藤明、冨川直樹、千葉英樹
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08699
[Presentation] タイト結合分子クローディン-6接着シグナルは子宮内膜癌の悪性形質を増強する2017
- Author(s)
  杉本幸太郎、小島学、田中瑞子、柏木維人、冨川直樹、千葉英樹
- Organizer
  第69回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-17K08699
[Presentation] 難治性がんにおけるLiver X 受容体の発現2016
- Author(s)
  柳田真衣, 柏木維人, Honglei Chen, 冨川直樹, 田中瑞子, 千葉英樹
- Organizer
  日本病理学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-16K19083
[Presentation] クローディン-6の上皮分化誘導シグナルには、SrcとBlkが機能している2015
- Author(s)
  冨川直樹、柏木維人、杉本幸太郎、千葉英樹
- Organizer
  第104回日本病理学会大会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26670191
[Presentation] 幹細胞の上皮分化誘導機構において、核内受容体とCldn6シグナルがタイト結合分子の転写活性化に与える影響2015
- Author(s)
  柏木維人、冨川直樹、杉本幸太郎、渡部哲也、柳田真衣、千葉英樹
- Organizer
  第104回日本病理学会大会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26670191
[Presentation] タイト結合分子クローディン-4の上皮分化誘導能の解析2015
- Author(s)
  柳沼奈々絵、冨川直樹、柏木維人、杉本幸太郎、千葉英樹
- Organizer
  第104回日本病理学会大会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26670191

1. 矢澤華子 (60438132)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. 矢澤卓也 (50251054)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
3. 石井順 (80749599)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. Chiba Hideki (00295346)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. IMURA TETSUYA (00405276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. TOMIKAWA NAOKI (80468587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. TANAKA MIZUKO (40583638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 杉本幸太郎 (40791009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. 齋藤明 (70791010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SATO Hanako

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results

kashiwagi korehito 柏木 維人

Kashiwagi Korehito 柏木 維人

Research Projects

Research Products

Co-Researchers

Elucidation of molecular mechanism that endocrine secretory granule biogenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular basis of tumorigenesis of pulmonary neuroendocrine cancer via REST and MYT1L

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

複数のクローディン分子連携による小細胞肺癌の悪性形質制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular basis of tumorigenesis in pulmonary adenocarcinomas of rare histologic types

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular basis of neuroendocrine lung carcinogenesis in association with dysfunction of RB1-family proteins

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of malignant phenotype in small cell lung cancer enhanced by claudinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Promotion of cancer progression by aberrant cell adhesion signaling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Developing novel treatment of refractory cancer by targeting Liver X Receptor and its metabolism related genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel direct reprogramming method using cell adhesion signal

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cell adhesion signals regulate the nuclear receptor activity2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of liver X receptors in normal and refractory carcinoma tissues of the human lung and pancreas2018

Author(s)

Journal Title

Data Source

[Journal Article] The liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] REST/PROX1遺伝子発現変化はクロモグラニン高発現細胞を増加させる2020

Author(s)

Organizer

Data Source

[Presentation] REST/PROX1遺伝子発現変化はクロモグラニン高発現細胞を増加させる2020

Author(s)

Organizer

kashiwagi korehito 柏木維人

Kashiwagi Korehito 柏木維人