Sato Kota 佐藤孝太

Researcher Number	50732327
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2016 – 2025: 東北大学, 医学系研究科, 助教 2015: 東北大学, 大学病院, 助教 2014: 東北大学, 大学病院, 助手
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology Except Principal Investigator Basic Section 56060:Ophthalmology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Ophthalmology
Keywords	Principal Investigator 緑内障 / トランスクリプトーム / トラスクリプト―ム解析 / トランスクリプトーム解析 / メタボローム解析 / 網膜神経節細胞 / オミックス / メタボロミクス / 視神経障害 / 神経保護 / Ecel1 / 細胞死 … More Except Principal Investigator … More 緑内障 / 網膜神経節細胞 / 眼圧 / 神経保護 / iPS / 線維化 / 酸化ストレス / STING / 加齢黄斑変性 / hexokinase 2 / 免疫 / 神経保護効果 / 眼圧上昇 / ミクログリア / 疾患関連マイクログリア / 炎症 / Rhoキナーゼ / 活性化アストロサイト / 炎症性マイクログリアクラスター / 活性化マイクログリア / 視神経挫滅 / GPR84 / 再生医療 / 視神経 / 移植医療 / iPS細胞 / iPS細胞由来網膜神経節細胞 / ヒトiPS細胞由来網膜神経節細胞 / 網膜神経節細胞移植 / 動物モデル / 脆弱性 / 統合解析 / トランス臣クス / 線維柱帯 / メタボローム解析 / プロテオーム解析 / リピドーム解析 / 細胞外小胞 / リピドミクス / Glaucoma / CRISPR / ゲノム解析 / CRISPRスクリーニング / ゲノムワイド関連解析 / 手術 / 瘢痕抑制薬 / ナノ粒子 / 薬剤開発 / 瘢痕抑制 / 濾過手術 / 眼科 / in vivoイメージング / RGC / E-SARE / アデノ随伴ウイルス Less

非ヒト霊長類を用いた眼血流不全による正常眼圧緑内障の病態解明Principal Investigator
- Principal Investigator
  
  佐藤孝太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
ヒト緑内障GWASからの個別化創薬プラットフォーム構築研究
- Principal Investigator
  
  中澤徹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Drug discovery for the treatment of glaucoma by targeting hexokinase 2
- Principal Investigator
  
  横山悠
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Challenges for Breakthroughs in Social Implementation of Glaucoma Optic Nerve Regeneration Therapy
- Principal Investigator
  
  中澤徹
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
STING経路に着目した滲出型加齢黄斑変性の網膜下線維化の病態解明
- Principal Investigator
  
  安田正幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
マーモセットを用いた緑内障関連遺伝子の病態解明Principal Investigator
- Principal Investigator
  
  佐藤孝太
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
疾患関連マイクログリアクラスター制御による視神経保護治療
- Principal Investigator
  
  大石路子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
眼圧上昇時のミクログリア起因性炎症反応の制御による神経保護の可能性
- Principal Investigator
  
  石川誠
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Development of scarring quantification technology and nanoparticles for inhibition of bleb scarring with high tissue penetration
- Principal Investigator
  
  Tsuda Satoru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Comprehensive mechanism of elevated intraocular pressure by trans-omics analysis among anterior segment tissues.
- Principal Investigator
  
  Yokoyama Yu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Exploring glaucoma damage signaling pathways involved in vulnerability by retinal ganglion cells using integrated analysis
- Principal Investigator
  
  Omodaka Kazuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Retinal optic nerve regeneration by human iPS cell-derived retinal ganglion cells and artificial sieve plate transplantation
- Principal Investigator
  
  Nakazawa Toru
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
Identification of glaucoma susceptibility genes by CRISPR screening
- Principal Investigator
  
  Nakazawa Toru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Pathomechanisms of mouse models of optic neuropathy by integrated omics analysisPrincipal Investigator
- Principal Investigator
  
  Sato Kota
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
elucidation of pathophysiology of glaucoma model mouse by metabolomicsPrincipal Investigator
- Principal Investigator
  
  Sato Kota
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University
In vivo imaging of retinal ganglion cell function using adeno-associated virus
- Principal Investigator
  
  Nakazawa Toru
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University
Functional analysis of Ecel 1 in animal model of glaucoma and its application to therapyPrincipal Investigator
- Principal Investigator
  
  Sato Kota
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University
緑内障モデルマウスを用いた神経節細胞障害におけるネクロプトーシス細胞死経路の解析Principal Investigator
- Principal Investigator
  
  佐藤孝太
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University

All 2023 2022 2018 2017 Other

All Journal Article Presentation Patent Other

[Journal Article] The GPR84 molecule is a mediator of a subpopulation of retinal microglia that promote TNF/IL-1α expression via the rho-ROCK pathway after optic nerve injury2023
- Author(s)
  Sato Kota、Ohno‐Oishi Michiko、Yoshida Masaaki、Sato Taimu、Aizawa Takaharu、Sasaki Yuto、Maekawa Shigeto、Ishikawa Makoto、Omodaka Kazuko、Kawano Chihiro、Ohue‐Kitano Ryuji、Kimura Ikuo、Nakazawa Toru
- Journal Title
  
  Glia
  
  Volume: 71 Issue: 11 Pages: 2609-2622
- DOI
  10.1002/glia.24442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09805, KAKENHI-PROJECT-22K09827
[Journal Article] Neurosteroids as stress modulators and neurotherapeutics: lessons from the retina.2023
- Author(s)
  Izumi Y, Ishikawa M, Nakazawa T, Kunikata H, Sato K, Covey DF, Zorumski CF.
- Journal Title
  
  Neural Regen Res.
  
  Volume: 18 Issue: 5 Pages: 1004-1008
- DOI
  10.4103/1673-5374.355752
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09827
[Journal Article] Reduced Plasma BDNF Levels in Normal Tension Glaucoma Compared to Open Angle Glaucoma2023
- Author(s)
  Sato Kota、Takada Naoko、Fujioka Amane、Himori Noriko、Yokoyama Yu、Tsuda Satoru、Omodaka Kazuko、Kirihara Tomoko、Ishikawa Makoto、Kunikata Hiroshi、Nakazawa Toru
- Journal Title
  
  Journal of Glaucoma
  
  Volume: 32 Issue: 9 Pages: 734-737
- DOI
  10.1097/ijg.0000000000002257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09827, KAKENHI-PROJECT-21K09736
[Journal Article] Glaucoma and microglia-induced neuroinflammation2023
- Author(s)
  Ishikawa M, Izumi Y, Sato-K, Sato T, Zorumski CF, Kunikata H, Nakazawa T.
- Journal Title
  
  Front. Ophthalmol.
  
  Volume: - Pages: 1-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09827
[Patent] 視神経障害の診断用バイオマーカー2018
- Inventor(s)
  中澤徹、佐藤孝太、三枝大輔
- Industrial Property Rights Holder
  中澤徹、佐藤孝太、三枝大輔
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K16958
[Patent] 視神経障害の診断用バイオマーカー2017
- Inventor(s)
  中澤徹、佐藤孝太、三枝大輔
- Industrial Property Rights Holder
  中澤徹、佐藤孝太、三枝大輔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-238492
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K16958
[Presentation] Induction of microglia-induced neuroinflammation in a rat ex vivo glaucoma model2023
- Author(s)
  Taimu Sato, Makoto Ishikawa, Kota Sato, Hiroshi Tawarayama and Toru Nakazawa
- Organizer
  10th World Glaucoma Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09827
[Presentation] GPR84はTNF/IL-1を高発現する網膜マイクログリアのマーカーである2023
- Author(s)
  佐藤孝太、大石路子、中澤徹
- Organizer
  第127回日本眼科学会
- Data Source
  KAKENHI-PROJECT-22K09805
[Presentation] The neurosteroid allopregnanolone and its enantiomer protect retinal neurons by effects on autophagy in rat glaucoma models2023
- Author(s)
  Makoto Ishikawa, Taimu Sato, Kota Sato, Hiroshi Kunikata and Toru Nakazawa
- Organizer
  日中韓Joint meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09827
[Presentation] 血漿プロテオーム解析による緑内障自己抗体の同定2023
- Author(s)
  高田菜生子、石川誠、佐藤孝太、國方彦志、福田枝里子、山口圭、小野千紘、桐原朋子、新谷千栄、五島直樹、中澤徹
- Organizer
  第34回日本緑内障学会
- Data Source
  KAKENHI-PROJECT-22K09827
[Presentation] ラットex vivo緑内障モデルにおける眼圧上昇時のNLRP3介在型炎症反応の誘導2023
- Author(s)
  佐藤大夢、石川誠、大石路子、神位りえ子、佐藤孝太、中澤徹
- Organizer
  第127回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-22K09827
[Presentation] ラット ex vivo 緑内障モデルにおけるCSF1受容体拮抗薬(PLX5622)によるNLRP3介在型炎症反応抑制の検討2023
- Author(s)
  佐藤大夢、石川誠、大石路子、神位りえ子、佐藤孝太、中澤徹
- Organizer
  第34回日本緑内障学会
- Data Source
  KAKENHI-PROJECT-22K09827
[Presentation] ラットex vivo緑内障モデルにおける眼圧上昇時のミクログリアによる網膜神経節細胞傷害のメカニズムについて2023
- Author(s)
  佐藤大夢、石川誠、大石路子、神位りえ子、俵山寛司、佐藤孝太、中澤徹
- Organizer
  第11 回わかもと先進眼科医療研究会（WACAMOTO）
- Data Source
  KAKENHI-PROJECT-22K09827
[Presentation] 学術展示ラット緑内障モデルにおけるNMDAチャンネル透過型プローブAGBによる神経保護メカニズムの検討2022
- Author(s)
  石川誠、佐藤大夢、大石路子、神位りえ子、佐藤孝太、中澤徹
- Organizer
  第33回日本緑内障学会
- Data Source
  KAKENHI-PROJECT-22K09827
[Presentation] ラット緑内障モデルにおける神経ステロイド光学異性体の神経保護作用2022
- Author(s)
  石川誠, 佐藤大夢, 佐藤孝太, 國方彦志, 吉冨健志, 中澤徹
- Organizer
  第126回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-22K09827
[Presentation] Metabolomic analysis of optic nerve-injured mouse retina2018
- Author(s)
  Kota Sato, Daisuke Saigusa, Ikuko N. Motoike, Ritsumi Saito, Amane Fujioka, Masayuki Yamamoto, Toru Nakazawa
- Organizer
  The 29th Meeting of Japan Glaucoma Society
- Data Source
  KAKENHI-PROJECT-17K16958
[Presentation] マウス緑内障モデル網膜のメタボローム解析2017
- Author(s)
  佐藤孝太
- Organizer
  日本眼科学会
- Data Source
  KAKENHI-PROJECT-17K16958
[]

1. Nakazawa Toru (30361075)

# of Collaborated Projects: 10 results

# of Collaborated Products: 2 results
2. Tsuda Satoru (60791093)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. Yokoyama Yu (00597312)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 小林航 (20646442)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 石川誠 (10212854)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
6. 國分太貴 (30646443)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 大石路子 (80454875)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Omodaka Kazuko (80569583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西口康二 (30447825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 藤田幸輔 (80708115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 村山奈美枝 (60597516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 笠井均 (30312680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小関良卓 (80780634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 矢花武史 (30725213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 前川重人 (80625294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 三枝大輔 (90545237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 岡田眞里子 (10342833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Sharma Parmanand (80451623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 杉江淳 (50777000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 國方彦志 (40361092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 安田正幸 (00569585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 俵山寛司 (20402414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. OHNO Michiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Sato Kota 佐藤 孝太

Research Projects

Research Products

Co-Researchers

非ヒト霊長類を用いた眼血流不全による正常眼圧緑内障の病態解明Principal Investigator

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マーモセットを用いた緑内障関連遺伝子の病態解明Principal Investigator

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Pathomechanisms of mouse models of optic neuropathy by integrated omics analysisPrincipal Investigator

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elucidation of pathophysiology of glaucoma model mouse by metabolomicsPrincipal Investigator

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Project Period (FY)

Sato Kota 佐藤孝太

[Patent] 視神経障害の診断用バイオマーカー2018