• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Kawashima Atsunari  河嶋 厚成

ORCIDConnect your ORCID iD *help
Researcher Number 50746568
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 大阪大学, 大学院医学系研究科, 講師
2017 – 2021: 大阪大学, 医学系研究科, 助教
2016: 大阪大学, 医学系研究科, 寄附講座助教
2015: 大阪大学, 医学(系)研究科(研究院), 特任助教〈常勤)
Review Section/Research Field
Principal Investigator
Basic Section 56030:Urology-related / Urology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Except Principal Investigator
Basic Section 56030:Urology-related
Keywords
Principal Investigator
尿路上皮癌 / 制御性T細胞 / 腎細胞癌 / 膀胱癌 / 血液 / 細菌叢 / Dアミノ酸 / CD31 / 血管新生 / エクソソーム … More / Cutibacterium acnes / 細胞外小胞 / Firmicutes / 癌免疫療法 / 細菌関連代謝物 / 血液内細菌叢 / 転移 / RNA修飾 / ノックアウトマウス / CCR8 / シングルセルシークエンス / 新規治療標的 / 癌免疫 / 泌尿器科癌 / 疲弊化T細胞 / Tim-3 / 腫瘍悪性度 / 予後予測 / 効果予測 / ニボルマブ / TIM-3 / PD-1 … More
Except Principal Investigator
尿路上皮癌 / RNA修飾 / 上部尿路腫瘍 / 空間的不均一性 / 腸内細菌叢 / 前立腺癌 / 血液細菌叢 / 腫瘍微小環境 / 腫瘍免疫 / 腫瘍代謝 / Dアラニン / 早期血液診断薬 / Dアミノ酸 / 腎癌組織内免疫 / 血液内細菌情報 / 細菌遺伝情報 / 細胞外小胞 / 腎細胞癌 Less
  • Research Projects

    (10 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (12 People)
  •  前立腺癌における腸内細菌叢が制御する免疫療法関連RNA修飾の解明と治療標的の探索

    • Principal Investigator
      松下 慎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  時空間的トランスクリプトーム解析による上部尿路上皮癌の進展・薬剤耐性機序の解明

    • Principal Investigator
      石津谷 祐
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  尿路上皮癌のRNA修飾によるエピトランスクリプトムの解明と新規治療戦略創成

    • Principal Investigator
      山本 致之
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  癌転移に関与するRNA修飾メカニズムの解明と新規治療法の開発Principal Investigator

    • Principal Investigator
      河嶋 厚成
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Osaka University
  •  腎細胞癌局所内免疫状態を構築する血液内細菌叢の同定

    • Principal Investigator
      植村 俊彦
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  尿路上皮癌患者におけるD-アミノ酸発現意義の解明

    • Principal Investigator
      山本 顕生
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  Elucidation of the cancer local immune status constructed by the systemic circulating microbiome and bacterial-related metabolism in urogenital cancerPrincipal Investigator

    • Principal Investigator
      河嶋 厚成
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  Development of cancer immunotherapy for urothelial carcinoma targeting tissue infiltrating regulatory T cellsPrincipal Investigator

    • Principal Investigator
      KAWASHIMA ATSUNARI
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  Clarification of immune status in urological cancer tissues and identification for novel therapeutic targetsPrincipal Investigator

    • Principal Investigator
      Kawashima Atsunari
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Osaka University
  •  Identification of new therapeutic items for drug resistant metastatic urothelial carcinomaPrincipal Investigator

    • Principal Investigator
      Kawashima Atsunari
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Osaka University

All 2024 2023 2022 2019 2018 2017

All Journal Article Presentation Patent

  • [Journal Article] Cutibacterium acnes‐derived extracellular vesicles promote tumor growth in renal cell carcinoma2024

    • Author(s)
      Jingushi Kentaro、Kawashima Atsunari、Tanikawa Sayaka、Saito Takuro、Yamamoto Akinaru、Uemura Toshihiro、Sassi Nesrine、Ishizuya Yu、Yamamoto Yoshiyuki、Kato Taigo、Hatano Koji、Hase Hiroaki、Nonomura Norio、Tsujikawa Kazutake
    • Journal Title

      Cancer Science

      Volume: 1 Issue: 8 Pages: 1-1

    • DOI

      10.1111/cas.16202

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Journal Article] Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma2023

    • Author(s)
      Uemura Toshihiro、Kawashima Atsunari、Jingushi Kentaro、Motooka Daisuke、Saito Takuro、Nesrine Sassi、Oka Toshiki、Okuda Yohei、Yamamoto Akinaru、Yamamichi Gaku、Tomiyama Eisuke、Ishizuya Yu、Yamamoto Yoshiyuki、Kato Taigo、Hatano Koji、Tsujikawa Kazutake、Wada Hisashi、Nonomura Norio
    • Journal Title

      Heliyon

      Volume: 9 Issue: 9 Pages: e19800-e19800

    • DOI

      10.1016/j.heliyon.2023.e19800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09469, KAKENHI-PROJECT-23K24472
  • [Journal Article] Circulating extracellular vesicles carrying Firmicutes reflective of the local immune status may predict clinical response to pembrolizumab in urothelial carcinoma patients2022

    • Author(s)
      Jingushi Kentaro,Kawashima Atsunari、Saito Takuro、Kanazawa Takayuki、Motooka Daisuke、Kimura Tomonori、Mita Masashi、Yamamoto Akinaru、Uemura Toshihiro、Yamamichi Gaku、Okada Koichi、Tomiyama Eisuke、Koh Yoko、Matsushita Makoto、Kato Taigo、Hatano Koji、Uemura Motohide、Tsujikawa Kazutake、Wada Hisashi、Nonomura Norio
    • Journal Title

      Cancer Immunology, Immunotherapy

      Volume: 71 Issue: 12 Pages: 2999-3011

    • DOI

      10.1007/s00262-022-03213-5

    • Data Source
      KAKENHI-PROJECT-21K20968, KAKENHI-PROJECT-23K24472
  • [Journal Article] Phenotypic Analysis of Tumor Tissue?Infiltrating Lymphocytes in Tumor Microenvironment of Bladder Cancer and Upper Urinary Tract Carcinoma2019

    • Author(s)
      Kawashima Atsunari、Kanazawa Takayuki、Jingushi Kentaro、Kato Taigo、Ujike Takeshi、Nagahara Akira、Fujita Kazutoshi、Morimoto-Okazawa Akiko、Iwahori Kota、Uemura Motohide、Imamura Ryoichi、Wada Hisashi、Nonomura Norio
    • Journal Title

      Clinical Genitourinary Cancer

      Volume: 17 Issue: 2 Pages: 114-124

    • DOI

      10.1016/j.clgc.2018.11.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16790, KAKENHI-PROJECT-19H03729
  • [Patent] 癌の種類についての情報を提供する方法2023

    • Inventor(s)
      河嶋厚成、野々村祝夫、今村亮一、山本顕生、木村友則、三田真史
    • Industrial Property Rights Holder
      河嶋厚成、野々村祝夫、今村亮一、山本顕生、木村友則、三田真史
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-036041
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Presentation] 尿路上皮癌におけるRNA修飾クラスターの生物学的意義解明2023

    • Author(s)
      山本致之、河嶋厚成、長谷拓明、宮崎陽平、堀部祐輝、山道 岳、石津谷祐、加藤大悟、波多野浩士、野々村祝夫
    • Organizer
      第33回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-23K08778
  • [Presentation] 20.尿路性器癌患者の血液内細菌遺伝情報を用いた予後予測リキッドバイオプシーの可能性2023

    • Author(s)
      河嶋厚成ら
    • Organizer
      第61回 日本癌治療学会
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Presentation] 4.Development of novel cancer immunotherapy based on the circulating microbiome2023

    • Author(s)
      河嶋厚成ら
    • Organizer
      第110回 日本泌尿器科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Presentation] Implications of RNA modification clusters in urothelial carcinoma2023

    • Author(s)
      Yoshiyuki Yamamoto, Atsunari Kawashima, Hiroaki Hase, Yohei Miyazaki, Yuki Horibe, Masaru Tani, Nesrine Sassi, Toshihiro Uemura, Akinaru Yamamoto, Gaku Yamamichi, Kosuke Nakano, Yu Ishizuya, Taigo Kato, Koji Hatano, Norio Nonomura
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K08778
  • [Presentation] Establishment of Blood-based Diagnostic Markers of Urothelial Carcinoma Using Chiral Amino Acids2023

    • Author(s)
      Atunari Kawashima et al.
    • Organizer
      米国泌尿器科学会総会 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Presentation] 16.血液内細菌遺伝情報・代謝情報に基づいた新規バイオマーカーの開発2023

    • Author(s)
      河嶋厚成
    • Organizer
      Urologist Forum in Osaka 2023
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Presentation] D-asparagine could become a novel blood-based diagnostic marker for urothelial carcinoma patients.2023

    • Author(s)
      Atunari Kawashima et al.
    • Organizer
      EMUC 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Presentation] 血液内細菌叢の多様性は、癌免疫療法の治療効果を予測する2022

    • Author(s)
      河嶋厚成
    • Organizer
      日本泌尿器腫瘍学会
    • Data Source
      KAKENHI-PROJECT-23K24472
  • [Presentation] 膀胱癌と上部尿路上皮癌における癌局所内免疫状態の比較2018

    • Author(s)
      河嶋厚成
    • Organizer
      第77回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-17K16790
  • [Presentation] Overall dysfunction of T cells was significantly correlated with tumor grade in Renal Cell Carcinoma patients2018

    • Author(s)
      Atsunari Kawashima
    • Organizer
      35th Korea-Japan Urological Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16790
  • [Presentation] The significance as a prognostic predictor of immunological phenotype in urothelial carcinoma varies depending on the tumor sites2018

    • Author(s)
      Atsunari Kawashima
    • Organizer
      Asia Urological Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16790
  • [Presentation] 腎細胞癌の腫瘍悪性度は癌組織内T細胞の機能低下と有意な相関示す2018

    • Author(s)
      河嶋厚成
    • Organizer
      第68回日本泌尿器科学会中部総会
    • Data Source
      KAKENHI-PROJECT-17K16790
  • [Presentation] 尿路上皮癌における腫瘍浸潤T細胞サブセット解析2017

    • Author(s)
      河嶋 厚成
    • Organizer
      泌尿器分子細胞研究会
    • Place of Presentation
      大分
    • Year and Date
      2017-03-10
    • Data Source
      KAKENHI-PROJECT-15K20085
  • 1.  野々村 祝夫 (30263263)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 4 results
  • 2.  神宮司 健太郎 (80707571)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  和田 尚 (70243459)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  長谷 拓明 (80779926)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  木村 友則 (00631300)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  植村 俊彦 (60905941)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  山本 顕生 (50909653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  松下 慎 (40824785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  石津谷 祐 (00783854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  元岡 大祐 (10636830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  西塔 拓郎 (20646468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  山本 致之 (90759557)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi