Fujita koji 藤田浩二

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Fujita Koji 藤田浩二

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Researcher Number	50749421
Other IDs	https://orcid.org/0000-0001-9390-7565
Affiliation (Current)	2024: 香川大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2022: 香川大学, 医学部附属病院, 助教 2016 – 2018: 香川大学, 医学部附属病院, 病院助教 2015: 香川大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / General internal medicine(including psychosomatic medicine) Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 52010:General internal medicine-related / Laboratory medicine / Gastroenterology / Tumor diagnostics
Keywords	Principal Investigator miRNA / microRNA / 薬剤耐性 / 肝細胞癌 / 耐性 / Microarray / プロテオーム解析 / Hepatitis B virus / NTCP-1 / HBV … More / 感染症 / B型肝炎 / 遺伝子 / 老化 / メタボリック症候群 / 癌 / 加齢 / トランスジェニックマウス / Transgenic mouse … More Except Principal Investigator microRNA / 肝細胞癌 / ガレクチン-9 / 耐性株 / 分子標的治療薬 / 抗がん作用 / エピガロカテキンガレート / Galectin-9 / Galectin-9 microRNA / 胆管細胞癌 / エクソソーム / 転移性肝癌 / micro RNA / 生活習慣病 / ARB / 降圧薬 / 新規化学予防薬 / テルミサルタン / 化学予防薬 / 抗腫瘍薬 / 間葉系腫瘍 / 大腸癌 / 自己免疫性肝疾患 / 原発性胆汁性胆管炎 / トランスレーショナルリサーチ / 分子生物学 / ガレクチン9 / ガレクチン９ / マイクロRNA / 非アルコール性脂肪性肝炎 / Ｇａｌ-9 / Ｇａｌ－９ / Gal-9 / バイオマーカー / exosome / 消化管間葉系腫瘍 / 消化管粘膜下腫瘍 Less

Functional analysis of miRNA in anti-cancer drug-resistance of hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  藤田浩二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagawa University
Examination of the effect of combination therapy of galectin-9 and epigallocatechin gallate on hepatocellular carcinoma
- Principal Investigator
  
  正木勉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagawa University
Pegylated interferon therapy-related microRNA-6126 downregulates sodium taurocholate cotransporting polypeptide expression in hepatocytesPrincipal Investigator
- Principal Investigator
  
  Fujita Koji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagawa University
Anti-tumor effect of Galectin-9 on metastatic hepatocellular carcinoma and its microRNA basis
- Principal Investigator
  
  Masaki Tsutomu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagawa University
Prediction of prognosis targeting microRNAs in exosomes in primary biliary cholangitis
- Principal Investigator
  
  Nomura Takako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagawa University
Antitumor effects of lifestyle drugs on colorectal cancer: Involvement of antihypertensive drug ARB as a novel chemopreventive agent
- Principal Investigator
  
  Kobara Hideki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagawa University
Identification of microRNAs that regulate Galectin 9 to suppress nonalcoholic steatohepatitis progression
- Principal Investigator
  
  Morishita Asahiro
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagawa University
Functional analysis of miR-301a in aging, metabolic syndrome and carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Fujita Koji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Kagawa University
Basic study on treatment of hepatocellular carcinoma targetted of Gal-9 exosomes
- Principal Investigator
  
  Masaki Tsutomu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University
Elucidation of pathway and prognostic factor prediction derived from microRNA analysis in gastrointestinal submucosal tumor
- Principal Investigator
  
  Kobara Hideki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kagawa University

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Telmisartan Inhibits Cell Proliferation and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inducing S-Phase Arrest In Vitro and In Vivo.2019
- Author(s)
  Matsui T, Chiyo T, Kobara H, Fujihara S, Fujita K, Namima D, Nakahara M, Kobayashi N, Nishiyama N, Yachida T, Morishita A, Iwama H, Masaki T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Issue: 13 Pages: 13-13
- DOI
  10.3390/ijms20133197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11023
[Journal Article] Galectin-9 Induces Mitochondria-Mediated Apoptosis of Esophageal Cancer In Vitro and In Vivo in a Xenograft Mouse Model.2019
- Author(s)
  Chiyo T, Fujita K, Iwama H, Fujihara S, Tadokoro T, Ohura K, Matsui T, Goda Y, Kobayashi N, Nishiyama N, Yachida T, Morishita A, Kobara H, Mori H, Niki T, Hirashima M, Himoto T, Masaki T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Issue: 11 Pages: 11-11
- DOI
  10.3390/ijms20112634
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11023, KAKENHI-PROJECT-19K16747
[Journal Article] Fibrosis Staging Using Direct Serum Biomarkers is Influenced by Hepatitis Activity Grading in Hepatitis C Virus Infection.2018
- Author(s)
  Fujita K, Kuroda N, Morishita A, Oura K, Tadokoro T, Nomura T, Yoneyama H, Arai T, Himoto T, Watanabe S, Masaki T.
- Journal Title
  
  J Clin Med
  
  Volume: 7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients.2018
- Author(s)
  Fujita K, Mimura S, Iwama H, Nakahara M, Oura K, Tadokoro T, Nomura T, Tani J, Yoneyama H, Morishita A, Oryu M, Himoto T, Nishitsuji H, Shimotohno K, Omata M, Masaki T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19(7)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9 ameliorates fulminant liver injury.2017
- Author(s)
  Tadokoro T, Morishita A, Sakamoto T, Fujihara S, Fujita K, Mimura S, Oura K, Nomura T, Tani J, Yoneyama H, Iwama H, Himoto T, Niki T, Hirashima M, Masaki T
- Journal Title
  
  Mol Med Rep
  
  Volume: 16(1) Issue: 1 Pages: 36-42
- DOI
  10.3892/mmr.2017.6606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Therapeutic potential of the antidiabetic drug metformin in small bowel adenocarcinoma.2017
- Author(s)
  Chiyo T, Kato K, Iwama H, Fujihara S, Fujita K, Tadokoro T, Ohura K, Samukawa E, Yamana Y, Kobayashi N, Matsunaga T, Nishiyama N, Ayaki M, Yachida T, Morishita A, Kobara H, Mori H, Masaki T.
- Journal Title
  
  Int J Oncol
  
  Volume: 50(6) Issue: 6 Pages: 2145-2153
- DOI
  10.3892/ijo.2017.3971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] icroRNA profile of hepatic epithelioid hemangioendothelioma: A case report.2017
- Author(s)
  Morishita A, Iwama H, Yoneyama H, Sakamoto T, Fujita K, Nomura T, Tani J, Miyoshi H, Fujihara S, Nishiyama N, Kobara H, Mori H, Yamamoto N, Okano K, Suzuki Y, Ibuki E, Haba R, Himoto T, Masaki T.
- Journal Title
  
  Oncol Lett
  
  Volume: 13(3) Issue: 3 Pages: 1655-1659
- DOI
  10.3892/ol.2017.5643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Comparison of submucosal tunneling biopsy versus EUS-guided FNA for gastric subepithelial lesions: a prospective study with crossover design2017
- Author(s)
  Kobara Hideki、Mori Hirohito、Nishimoto Naoki、Fujihara Shintaro、Nishiyama Noriko、Ayaki Maki、Yachida Tatsuo、Matsunaga Tae、Chiyo Taiga、Kobayashi Nobuya、Fujita Koji、Kato Kiyohito、Kamada Hideki、Oryu Makoto、Tsutsui Kunihiko、Iwama Hisakazu、Haba Reiji、Masaki Tsutomu
- Journal Title
  
  Endoscopy International Open
  
  Volume: 05 Issue: 08 Pages: E695-E705
- DOI
  10.1055/s-0043-112497
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06855
[Journal Article] Galectin-9: An anticancer molecule for gallbladder carcinoma.2016
- Author(s)
  Tadokoro T, Morishita A, Fujihara S, Iwama H, Niki T, Fujita K, Akashi E, Mimura S, Oura K, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Himoto T, Hirashima M, Masaki T.
- Journal Title
  
  Int J Oncol
  
  Volume: 48 Issue: 3 Pages: 1165-1174
- DOI
  10.3892/ijo.2016.3347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9 suppresses the proliferation of gastric cancer cells in vitro.2016
- Author(s)
  Takano J, Morishita A, Fujihara S, Iwama H, Kokado F, Fujikawa K, Fujita K, Chiyo T, Tadokoro T, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Mori H, Niki T, Hirashima M, Masaki T.
- Journal Title
  
  Oncol Rep
  
  Volume: 35 Issue: 2 Pages: 851-860
- DOI
  10.3892/or.2015.4452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
[Journal Article] Differences in miRNA expression profiles between GIST and leiomyoma in human samples acquired by submucosal tunneling biopsy.2015
- Author(s)
  Fujita K, Kobara H, Masaki T, et al.
- Journal Title
  
  Endosc Int Open.
  
  Volume: 6 Issue: 06 Pages: 665-671
- DOI
  10.1055/s-0034-1393077
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06855
[Presentation] miRNAによるNTCP 発現抑制効果の検討2022
- Author(s)
  藤田浩二
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-19K07941
[Presentation] microRNA-6126 Reduces the Stability of NTCP messenger RNA and Suppresses its Expression in Hepatocytes2021
- Author(s)
  Koji Fujita
- Organizer
  APASL Single Topic Conference in Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07941
[Presentation] miR-6126によるHBV-DNA増殖抑制効果の検討2020
- Author(s)
  藤田浩二
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K07941
[Presentation] 免疫チェックポイント分子ガレクチン-9 は，肝線維化と肝細胞癌を抑制する2019
- Author(s)
  藤田　浩二
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K09014
[Presentation] miR-762はDAA治療経過中のゲノタイプ1型HCV排除に際して血清中に増加する2018
- Author(s)
  米山弘人、森下朝洋、藤田浩二、野村貴子、坂本鉄平、田所智子、大浦杏子、谷　丈二、出口章広、樋本尚志、三村志麻、正木　勉
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] 慢性肝疾患における血清ガレクチン9濃度の診断的意義の検討2018
- Author(s)
  藤田浩二、樋本尚志、正木　勉
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] C型肝炎起因性肝細胞癌におけるバイオマーカーとしての血清miR-125a-5pの有用性2018
- Author(s)
  大浦杏子、田所智子、藤田浩二、三村志麻、坂本鉄平、野村貴子、森下朝洋、米山弘人、正木　勉
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] Serum galectin-9 levels are correlated to liver fibrosis regardless of chronic inflammation or hepatocellular carcinoma2017
- Author(s)
  Fujita K, Niki T, Himoto T, Masaki T.
- Organizer
  AASLD2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] Serum Concentration of Galectin-9 Correlates to Liver Fibrosis.2017
- Author(s)
  Fujita K, Morishita A, Yoneyama H, Niki T, Nishimoto N, Himoto T, Masaki T.
- Organizer
  APASL STC 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] Galectin-9による食道扁平上皮癌のアポトーシスの誘導と作用機序2017
- Author(s)
  千代大翔、藤原新太郎、森下朝洋、藤田浩二、山名佳美、大浦杏子、寒川英里、田所智子、小林伸也、松永多恵、西山典子、綾木麻紀、谷内田達夫、小原英幹、森　宏仁、正木　勉
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] 消化管低悪性度GISTと平滑筋腫のmicroRNAの発現プロフィールの比較～粘膜下トンネル生検法による採取サンプルを用いて～2015
- Author(s)
  藤田浩二，小原英幹
- Organizer
  日本消化器内視鏡学会
- Place of Presentation
  日本、名古屋
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-15K06855
[Presentation] Differences in miRNA expression profiles between GIST and leiomyoma in human samples acquired by submucosal tunneling biopsy.2015
- Author(s)
  Fujita K, Kobara H
- Organizer
  United European Gastroenterology Week 2015
- Place of Presentation
  Spain, barcelona
- Year and Date
  2015-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06855

1. Masaki Tsutomu (30335848)

# of Collaborated Projects: 8 results

# of Collaborated Products: 15 results
2. Morishita Asahiro (60423430)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
3. Kobara Hideki (10612476)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
4. IWAMA Hisakazu (20398035)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
5. Nomura Takako (70645415)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
6. 米山弘人 (80294750)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
7. 森宏仁 (20568844)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
8. 谷丈二 (00596075)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
9. 大森典子 (50613410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. 坂本鉄平 (30769328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 仁木敏朗 (40558508)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. 田所智子 (50813177)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 大浦杏子 (80834639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 藤原新太郎 (30612486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 千代大翔 (50769346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 中原麻衣 (00865610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Fujita koji 藤田 浩二

Fujita Koji 藤田 浩二

Research Projects

Research Products

Co-Researchers

Functional analysis of miRNA in anti-cancer drug-resistance of hepatocellular carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of the effect of combination therapy of galectin-9 and epigallocatechin gallate on hepatocellular carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pegylated interferon therapy-related microRNA-6126 downregulates sodium taurocholate cotransporting polypeptide expression in hepatocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anti-tumor effect of Galectin-9 on metastatic hepatocellular carcinoma and its microRNA basis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prediction of prognosis targeting microRNAs in exosomes in primary biliary cholangitis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Antitumor effects of lifestyle drugs on colorectal cancer: Involvement of antihypertensive drug ARB as a novel chemopreventive agent

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of microRNAs that regulate Galectin 9 to suppress nonalcoholic steatohepatitis progression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of miR-301a in aging, metabolic syndrome and carcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study on treatment of hepatocellular carcinoma targetted of Gal-9 exosomes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of pathway and prognostic factor prediction derived from microRNA analysis in gastrointestinal submucosal tumor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Telmisartan Inhibits Cell Proliferation and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inducing S-Phase Arrest In Vitro and In Vivo.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Galectin-9 Induces Mitochondria-Mediated Apoptosis of Esophageal Cancer In Vitro and In Vivo in a Xenograft Mouse Model.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibrosis Staging Using Direct Serum Biomarkers is Influenced by Hepatitis Activity Grading in Hepatitis C Virus Infection.2018

Author(s)

Journal Title

Data Source

[Journal Article] Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients.2018

Fujita koji 藤田浩二

Fujita Koji 藤田浩二