Nakamura Sou 中村壮

Researcher Number	50769833
Other IDs
Affiliation (Current)	2025: 京都大学, iPS細胞研究所, 特定講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 京都大学, iPS細胞研究所, 特定拠点講師 2018 – 2022: 京都大学, iPS細胞研究所, 特定拠点助教 2018: 京都大学, iPS細胞研究所, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 90:Biomedical engineering and related fields / Broad Section I
Keywords	Principal Investigator 血小板 / 巨核球細胞株 / cilia小胞 / カリウムイオン / 巨核球成熟 / 再生医療 / 巨核球分化 / c-MYC / 自己複製 / iPS / imMKCL / iPS細胞 / 巨核球 … More Except Principal Investigator … More 血小板 / 乱流 / iPS細胞 / 巨核球 / バイオリアクター / リンパ管腫症 / リンパ管 / ポドプラニン / CLEC-2 / リンパ管種症 / ゴーハム病 / 間葉系幹細胞 / 造血支持細胞 / インターフェロンシグナル / ヒト造血幹細胞 / 培養槽 / 脂質膜 / 造血システム / リアクター / shear stress / turbulence / エンドペプチダーゼ / 細胞膜 / 乱流エネルギー / ずり応力 / せん断ずり応力 Less

Ca2+オシレーションにおける巨核球成熟メカニズムの解明Principal Investigator
- Principal Investigator
  
  中村壮
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto University
Study of the regulation of self-renewal and differentiation of human hematopoietic stem cells via interferon signaling.
- Principal Investigator
  
  高山直也
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Chiba University
リンパ管腫症／ゴーハム病で認められた血小板活性化受容体CLEC-2異常の解析
- Principal Investigator
  
  井上克枝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  University of Yamanashi
巨核球成熟における一次絨毛由来小胞の生理機能解明および生体外血小板製造への応用Principal Investigator
- Principal Investigator
  
  中村壮
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto University
流体刺激シグナルの解明に基づく連続血小板製造非定常培養機器の開発
- Principal Investigator
  
  江藤浩之
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto University
Elucidating the fundamental mechanism of platelet biogenesis and its medical application
- Principal Investigator
  
  江藤浩之
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Kyoto University
Mechanism of turbulence mediated platelet biogenesis and application to ex vivo manufacturing of platelets
- Principal Investigator
  
  ETO KOJI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto University
New method for establishing self-renewing megakaryocyte cell lines using iPS cellsPrincipal Investigator
- Principal Investigator
  
  Nakamura Sou
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility2024
- Author(s)
  Chen Si Jing、Hashimoto Kazuya、Fujio Kosuke、Hayashi Karin、Paul Sudip Kumar、Yuzuriha Akinori、Qiu Wei-Yin、Nakamura Emiri、Kanashiro Maria Alejandra、Kabata Mio、Nakamura Sou、Sugimoto Naoshi、Kaneda Atsushi、Yamamoto Takuya、Saito Hirohide、Takayama Naoya、Eto Koji
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 2588-2588
- DOI
  10.1038/s41467-024-46605-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18299, KAKENHI-PROJECT-22K15124, KAKENHI-PROJECT-21H05047
[Journal Article] “iPS細胞由来血小板製剤の開発”2023
- Author(s)
  中村壮、江藤浩之
- Journal Title
  
  検査と技術
  
  Volume: 51 Pages: 44-47
- Data Source
  KAKENHI-PROJECT-22K18169
[Journal Article] Humanized mouse models with endogenously developed human natural killer cells for in?vivo immunogenicity testing of HLA class I-edited iPSC-derived cells2023
- Author(s)
  Flahou Charlotte、Morishima Tatsuya、Higashi Natsumi、Hayashi Yoshikazu、Xu Huaigeng、Wang Bo、Zhang Chaoqi、Ninomiya Atsushi、Qiu Wei-Yin、Yuzuriha Akinori、Suzuki Daisuke、Nakamura Sou、Manz Markus、Kaneko Shin、Hotta Akitsu、Takizawa Hitoshi、Eto Koji、Sugimoto Naoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 662 Pages: 76-83
- DOI
  10.1016/j.bbrc.2023.04.067
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18299, KAKENHI-PROJECT-21K08397, KAKENHI-PROJECT-21K08413, KAKENHI-PROJECT-21H05047
[Journal Article] PACSIN1 is indispensable for amphisome-lysosome fusion during basal autophagy and subsets of selective autophagy2022
- Author(s)
  Oe Yukako、Kakuda Keita、Yoshimura Shin-ichiro、Hara Naohiro、Hasegawa Junya、Terawaki Seigo、Kimura Yasuyoshi、Ikenaka Kensuke、Suetsugu Shiro、Mochizuki Hideki、Yoshimori Tamotsu、Nakamura Shuhei
- Journal Title
  
  PLOS Genetics
  
  Volume: 18 Issue: 6 Pages: e1010264-e1010264
- DOI
  10.1371/journal.pgen.1010264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-20KK0341, KAKENHI-PLANNED-21H05145, KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-20H03252, KAKENHI-PROJECT-21H02428, KAKENHI-PROJECT-19H03181, KAKENHI-PROJECT-21H05047
[Journal Article] Production and nonclinical evaluation of an autologous iPSC?derived platelet product for the iPLAT1 clinical trial2022
- Author(s)
  Sugimoto Naoshi、Nakamura Sou、Shimizu Shin、Shigemasa Akiko、Kanda Junya、Matsuyama Nobuki、Tanaka Mitsunobu、Hayashi Tomoya、Fuchizaki Akihiro、Nogawa Masayuki、Watanabe Naohide、Okamoto Shinichiro、Handa Makoto、Sawaguchi Akira、Momose Dai、Koh Ki-Ryang、Tani Yoshihiko、Takaori-Kondo Akifumi、Eto Koji
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 23 Pages: 6056-6069
- DOI
  10.1182/bloodadvances.2022008512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18169, KAKENHI-PROJECT-21H05047
[Journal Article] iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study2022
- Author(s)
  Sugimoto N, Nakamura S, Shimizu S, Shigemasa A, Kanda J, Matsuyama N, Tanaka M, Hayashi T, Fuchizaki A, Nogawa M, Watanabe N, Okamoto S, Handa M, Sawaguchi A, Momose D, Koh KR, Tani Y, Takaori-Kondo A, Eto K
- Journal Title
  
  Blood
  
  Volume: 140 Issue: 22 Pages: 2398-2402
- DOI
  10.1182/blood.2022017296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18169, KAKENHI-PROJECT-21H05047, KAKENHI-PROJECT-21H02956
[Journal Article] Development of platelet replacement therapy using human induced pluripotent stem cells2021
- Author(s)
  Nakamura Sou、Sugimoto Naoshi、Eto Koji
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 63 Issue: 2 Pages: 178-186
- DOI
  10.1111/dgd.12711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22675, KAKENHI-PROJECT-18K18365, KAKENHI-PROJECT-18H04164, KAKENHI-PROJECT-21K08413
[Journal Article] Silencing of p53 and CDKN1A establishes sustainable immortalized megakaryocyte progenitor cells from human iPSCs2021
- Author(s)
  Sone Masamitsu、Nakamura Sou、Umeda Sachiko、Ginya Harumi、Oshima Motohiko、Kanashiro Maria Alejandra、Paul Sudip Kumar、Hashimoto Kanae、Nakamura Emiri、Harada Yasuo、Tsujimura Kyoko、Saraya Atsunori、Yamaguchi Tomoyuki、Sugimoto Naoshi、Sawaguchi Akira、Iwama Atsushi、Eto Koji、Takayama Naoya
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Issue: 12 Pages: 2861-2870
- DOI
  10.1016/j.stemcr.2021.11.001
- NAID
  120007177810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18365, KAKENHI-PROJECT-20H03740, KAKENHI-PROJECT-20K08705, KAKENHI-PROJECT-21K08413, KAKENHI-PROJECT-21H05047
[Journal Article] Microfluidic Bioreactor Made of Cyclo-Olefin Polymer for Observing On-Chip Platelet Production2021
- Author(s)
  Kumon Hiroki、Sakuma Shinya、Nakamura Sou、Maruyama Hisataka、Eto Koji、Arai Fumihito
- Journal Title
  
  Micromachines
  
  Volume: 12 Issue: 10 Pages: 1253-1253
- DOI
  10.3390/mi12101253
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18365, KAKENHI-PROJECT-19J23654, KAKENHI-PROJECT-21H05047
[Journal Article] hree-dimensional microchannel reflecting cell size distribution for on-chip production of platelet-like particles2021
- Author(s)
  Sakuma, Shinya, Hiroki Kumon, Sou Nakamura, Yusuke Kasai, Koji Eto, Fumihito Arai
- Journal Title
  
  Microfluidics and Nanofluidics
  
  Volume: 25(36) Issue: 4 Pages: 36-36
- DOI
  10.1007/s10404-021-02433-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19J23654, KAKENHI-PROJECT-18H04164, KAKENHI-PROJECT-21H04957
[Journal Article] Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin β1-ILK-β-catenin-JUN axis2021
- Author(s)
  Yuzuriha Akinori、Nakamura Sou、Sugimoto Naoshi、Kihara Shunsuke、Nakagawa Masato、Yamamoto Takuya、Sekiguchi Kiyotoshi、Eto Koji
- Journal Title
  
  Stem Cell Research
  
  Volume: 53 Pages: 102287-102287
- DOI
  10.1016/j.scr.2021.102287
- NAID
  120007006753
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18365, KAKENHI-PROJECT-18H04164, KAKENHI-PROJECT-21H04957, KAKENHI-PROJECT-21K08413
[Journal Article] iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity.2020
- Author(s)
  Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, Akasaka M, Nakamura S, Higashi N, Xu H, Matsumoto T, Fujio K, Manz MG, Hotta A, Takizawa H, Eto K, Sugimoto N.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 14 Issue: 1 Pages: 49-59
- DOI
  10.1016/j.stemcr.2019.11.011
- NAID
  120006777032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22675, KAKENHI-PROJECT-18H04164, KAKENHI-PROJECT-18K16091
[Journal Article] Novel physico-chemical regulation mechanism enables the production of 100 billion platelets2020
- Author(s)
  Nakamura S, Eto K.
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 61 Issue: 6 Pages: 628-633
- DOI
  10.11406/rinketsu.61.628
- NAID
  130007869141
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18365
[Journal Article] Novel physico-chemical regulation mechanism enables the production of 100 billion platelets2020
- Author(s)
  中村　壮、江藤浩之
- Journal Title
  
  臨床血液
  
  Volume: 61(6) Pages: 628-633
- NAID
  130007869141
- Data Source
  KAKENHI-PROJECT-18H04164
[Journal Article] Ex vivo generation of platelet products from human iPS cells.2020
- Author(s)
  Nakamura S, Sugimoto N, Eto K.
- Journal Title
  
  Inflamm Regen.
  
  Volume: 40 Issue: 1 Pages: 10-10
- DOI
  10.1186/s41232-020-00139-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18365, KAKENHI-PROJECT-18H04164
[Journal Article] Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells2020
- Author(s)
  Takaishi K, Takeuchi M, Tsukamoto S, Takayama N, Oshima M, Kimura K, Isshiki Y, Kayamori K, Hino Y, Oshima-Hasegawa N, Mitsukawa S, Takeda Y, Mimura N, Ohwada C, Iseki T, Nakamura S, Eto K, Iwama A, Yokote K, Nakaseko C, Sakaida E
- Journal Title
  
  Haematologica
  
  Volume: 105 Issue: 5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04164
[Journal Article] Novel physico-chemical regulation mechanism enables the production of 100 billion platelets2020
- Author(s)
  中村壮、江藤浩之
- Journal Title
  
  臨床血液
  
  Volume: 61 Issue: 6 Pages: 628-633
- NAID
  130007869141
- Data Source
  KAKENHI-PROJECT-18H04164
[Journal Article] Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells.2019
- Author(s)
  Takaishi K, Takeuchi M, Tsukamoto S, Takayama N, Oshima M, Kimura K, Isshiki Y, Kayamori K, Hino Y, Oshima-Hasegawa N, Mitsukawa S, Takeda Y, Mimura N, Ohwada C, Iseki T, Nakamura S, Eto K, Iwama A, Yokote K, Nakaseko C, Sakaida E.
- Journal Title
  
  Haematologica.
  
  Volume: Sep 5 Issue: 5 Pages: 00-00
- DOI
  10.3324/haematol.2018.214841
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04164, KAKENHI-PROJECT-17K09901
[Journal Article] Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.2018
- Author(s)
  Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, Sakuma S, Ito K, Kumon H, Hirose H, Okamoto H, Nogawa M, Iwasaki M, Kihara S, Fujio K, Matsumoto T, Higashi N, Hashimoto K, Sawaguchi A, Harimoto KI, Nakagawa M, Yamamoto T, Handa M, Watanabe N, Nishi E, Arai F, Nishimura S, Eto K.
- Journal Title
  
  Cell
  
  Volume: 174(3) Issue: 3 Pages: 636-648
- DOI
  10.1016/j.cell.2018.06.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PUBLICLY-18H04694, KAKENHI-PROJECT-16H05156, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18H04164
[Journal Article] De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome2018
- Author(s)
  Toki Tsutomu、Yoshida Kenichi、Wang RuNan、Okuno Yusuke、Kataoka Keisuke、Shiraishi Yuichi、Ohga Shouichi、Kuramitsu Madoka、Hamaguchi Isao、Ohara Akira、Kanno Hitoshi、Miyano Satoru、Kojima Seiji、Ishiguro Akira、Sugita Kanji、Kenmochi Naoya、Takahashi Satoru、Eto Koji、Ogawa Seishi、Ito Etsuro
- Journal Title
  
  The American Journal of Human Genetics
  
  Volume: 103 Issue: 3 Pages: 440-447
- DOI
  10.1016/j.ajhg.2018.07.020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10041, KAKENHI-PROJECT-17K10093, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-18K07868, KAKENHI-PROJECT-18H04164
[Journal Article] Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations2018
- Author(s)
  Hiraku Takei, Yoko Edahiro, Shuichi Mano, Nami Masubuchi, Yoshihsa Mizukami, Misa Imai, Soji Morishita, Kyohei Misawa, Tomonori Ochiai, Satoshi Tsuneda, Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu
- Journal Title
  
  British Journal of Haematology
  
  Volume: 印刷中 Issue: 6 Pages: 791-802
- DOI
  10.1111/bjh.15266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J11017, KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-17K16195, KAKENHI-PROJECT-18K16126, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-18H04164
[Patent] 巨核球の製造方法2024
- Inventor(s)
  江藤浩之、中村壮、岡本陽己
- Industrial Property Rights Holder
  江藤浩之、中村壮、岡本陽己
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-020854
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21H05047
[Patent] 巨核球の製造方法2023
- Inventor(s)
  江藤浩之、中村壮、林秀樹、藤尾康裕、原田康男
- Industrial Property Rights Holder
  江藤浩之、中村壮、林秀樹、藤尾康裕、原田康男
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-21H05047
[Patent] 国立大学法人千葉大学,国立大学法人京都大学2020
- Inventor(s)
  髙山直也,江藤浩之,曽根正光,中村壮
- Industrial Property Rights Holder
  髙山直也,江藤浩之,曽根正光,中村壮
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-18K18365
[Patent] 血小板の製造方法2018
- Inventor(s)
  江藤浩之、中村壮、伊東幸敬
- Industrial Property Rights Holder
  京都大学、株式会社メガカリオン
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-504562
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18H04164
[Patent] 血小板の製造方法2018
- Inventor(s)
  江藤浩之、中村壮、伊東幸敬
- Industrial Property Rights Holder
  江藤浩之、中村壮、伊東幸敬
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H04164
[Patent] 血小板の製造方法および製造装置、ならびに血小板の製造装置における運転条件の決定方法2018
- Inventor(s)
  江藤浩之、中村壮、伊東幸敬、重盛智大、加藤好一
- Industrial Property Rights Holder
  京都大学、株式会社メガカリオン、佐竹化学機械工業株式会社(現 : 佐竹マルチミックス)
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-527964
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18H04164
[Presentation] "Turbulence Enhances Fine-Tuning of Mitochondria Delivery in Megakaryocyte Maturation Contributing to Biogenesis of High Quality Platelets"2023
- Author(s)
  EMIRI NAKAMURA, KOJI ETO
- Organizer
  American Society of Hematology Annual meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05047
[Presentation] Autologous transfusion to an aplastic anemia patient with alloimmune platelet transfusion refractoriness2021
- Author(s)
  Sugimoto N, Kanda J, Nakamura S, Kitano T, Hishizawa M, Kondo T, Shimizu S, Shigemasa A, Hirai H, Arai Y, Minami M, Tada H, Momose D, Koh KR, Nogawa M, Watanabe N, Okamoto S, Handa M, Sawaguchi A, Matsuyama N, Tanaka M, Hayashi T, Fuchizaki A, Tani Y, Takaori-Kondo A, Eto K
- Organizer
  63rd Annual Meeting of the American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05047
[Presentation] iPS細胞を用いた血小板の作製2020
- Author(s)
  中村　壮
- Organizer
  第14回日本血栓止血学会学術標準化委員会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K18365
[Presentation] iPS細胞を用いた血小板の作製2020
- Author(s)
  中村　壮
- Organizer
  第14回日本血栓止血学会学術標準化委員会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H04164
[Presentation] iPS細胞を用いた血小板の作製2020
- Author(s)
  中村壮、江藤浩之
- Organizer
  第14回日本血栓止血学会学術標準化委員会シンポジウム(Web)
- Data Source
  KAKENHI-PROJECT-18H04164
[Presentation] 自家iPS細胞由来血小板の臨床研究(iPLAT1)の経過報告2020
- Author(s)
  諫田淳也, 杉本直志, 中村壮, 北野俊行, 菱澤方勝, 近藤忠一, 清水伸, 重政亜紀子, 平位秀世, 南学, 渡邊直英, 野川誠之, 半田誠, 岡本真一郎, 谷慶彦, 江藤浩之, 高折晃史
- Organizer
  第82回日本血液学会学術集会プレナリーセッション, 京都
- Data Source
  KAKENHI-PROJECT-18H04164
[Presentation] 自家iPS細胞由来血小板の臨床研究（iPLAT1）の経過報告2020
- Author(s)
  諫田淳也，杉本直志，中村壮，北野俊行，菱澤方勝，近藤忠一，清水伸，重政亜紀子，平位秀世，南学，渡邊直英，野川誠之，半田誠，岡本真一郎，谷慶彦，江藤浩之，高折晃史
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18H04164

1. ETO KOJI (50286986)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. 高山直也 (10584229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 末次志郎 (70345031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 杉本直志 (10447956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 井上克枝 (10324211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大石沙織 (50894094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 築地長治 (20710362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 小関道夫 (60444303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 斎藤潤 (90535486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 寺脇正剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 大野美紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 菅野仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Sou 中村 壮

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Ca2+オシレーションにおける巨核球成熟メカニズムの解明Principal Investigator

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Study of the regulation of self-renewal and differentiation of human hematopoietic stem cells via interferon signaling.

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リンパ管腫症／ゴーハム病で認められた血小板活性化受容体CLEC-2異常の解析

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巨核球成熟における一次絨毛由来小胞の生理機能解明および生体外血小板製造への応用Principal Investigator

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流体刺激シグナルの解明に基づく連続血小板製造非定常培養機器の開発

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Elucidating the fundamental mechanism of platelet biogenesis and its medical application

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Mechanism of turbulence mediated platelet biogenesis and application to ex vivo manufacturing of platelets

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New method for establishing self-renewing megakaryocyte cell lines using iPS cellsPrincipal Investigator

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[Journal Article] A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility2024

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[Journal Article] “iPS細胞由来血小板製剤の開発”2023

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[Journal Article] Humanized mouse models with endogenously developed human natural killer cells for in?vivo immunogenicity testing of HLA class I-edited iPSC-derived cells2023

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[Journal Article] PACSIN1 is indispensable for amphisome-lysosome fusion during basal autophagy and subsets of selective autophagy2022

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[Journal Article] Production and nonclinical evaluation of an autologous iPSC?derived platelet product for the iPLAT1 clinical trial2022

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[Journal Article] iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study2022

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Nakamura Sou 中村壮