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Ouchi Kota  大内 康太

ORCIDConnect your ORCID iD *help
Researcher Number 50781291
Other IDs
Affiliation (Current) 2025: 東北大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help 2024 – 2025: 東北大学, 大学病院, 助教
2018 – 2022: 東北大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Basic Section 54010:Hematology and medical oncology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
遺伝子発現 / バイオマーカー / 遺伝子発現解析 / 遺伝子発現異常 / 播種性血管内凝固症候群 / 胃癌 / DIC / 抗EGFR抗体薬 / 大腸癌 / DNAメチル化 … More
Except Principal Investigator
… More DNAメチル化 / 大腸癌 / 腸内細菌 / メチル化 / EGFR / 薬物療法 / 頭頸部癌 / 診断と治療 / 分子機構 / 免疫学的微小環境 / シグナル伝達異常 / 薬剤抵抗性克服 / DNA高メチル化型大腸癌 / miR-193a-3p / 薬剤耐性 / 薬剤感受性 / 抗EGFR抗体薬 / BRAF変異型大腸癌 / 高DNAメチル化型大腸癌 Less
  • Research Projects

    (6 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (7 People)
  •  BRAF変異型高メチル化大腸癌に対する新規治療方法の開発Principal Investigator

    • Principal Investigator
      大内 康太
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tohoku University
  •  DNAメチル化状態に基づいた頭頸部癌薬物療法のバイオマーカー開発

    • Principal Investigator
      西條 憲
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Tohoku University
  •  腸内環境制御による高メチル化型大腸癌の新規予防・治療戦略の開発

    • Principal Investigator
      唐澤 秀明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Tohoku University
  •  Exploring aberrant gene expression associated with DIC coexistence in advanced gastric cancerPrincipal Investigator

    • Principal Investigator
      Ouchi Kota
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tohoku University
  •  Research on pathogenesis of DNA-highly methylated type colorectal cancer and the development of diagnosis and treatment methods

    • Principal Investigator
      ISHIOKA Chikashi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tohoku University
  •  Search for novel biomarkers to predict treatment sensitivity in colorectal cancerPrincipal Investigator

    • Principal Investigator
      Ouchi Kota
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tohoku University

All 2022 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] A modified MethyLight assay predicts the clinical outcomes of anti-epidermal growth factor receptor treatment in metastatic colorectal cancer2022

    • Author(s)
      Ouchi K, Takahashi S, Okita A, Sakamoto Y, Muto O, Amagai K, Okada T, Ohori H, Shinozaki E, Ishioka C.
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 3 Pages: 1057-1068

    • DOI

      10.1111/cas.15252

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03508
  • [Journal Article] Advanced colorectal cancer subtypes (aCRCS) help select oxaliplatin-based or irinotecan-based therapy for colorectal cancer.2021

    • Author(s)
      Takahashi S,Sakamoto Y,Denda T,Takashima A,Komatsu Y,Nakamura M,Ohori H,Yamaguchi T,Kobayashi Y,Baba H,Kotake M,Amagai K,Kondo H,Shimada K,Sato A,Yuki S,Okita A,Ouchi K,Komine K,Watanabe M,Morita S,Ishioka C.
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 4 Pages: 1567-1578

    • DOI

      10.1111/cas.14841

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03508
  • [Presentation] 高メチル化大腸がんが抗EGFR抗体薬抵抗性となる分子生物学的メカニズムの探索2020

    • Author(s)
      大内康太,高橋信,沖田啓,大槻泰史,石岡千加史
    • Organizer
      第24回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03508
  • [Presentation] Development of an in vitro diagnostic test to predict the clinical outcome of anti-EGFR treatment based on DNA methylation status.2020

    • Author(s)
      Ouchi K,Takahashi S,Ishioka C
    • Organizer
      7th US-Japan Workshop on Biomarkers for Cancer Early Detection.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03508
  • [Presentation] Analysis of consensus molecular subtypes (CMS) classification in the TRICOLORE trial: A randomized phase 3 trial of S-1 and irinotecan plus bevacizumab versus mFOLFOX6 or CapeOX plus bevacizumab as first-line treatment for metastatic colorectal cancer.2020

    • Author(s)
      1.Yuki S,Gamoh M,Denda T,Takashima A,Takahashi S,Nakamura M,Ohori H,Yamaguchi T,Kobayashi Y,Baba H,Kotake M,Amagi K,Kondo H,Shimada K,Sato A,Ishioka C,Komine K,Ouchi K,Morita S,Komatu Y
    • Organizer
      ASCO 2020 Gastrointestinal Cancers Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03508
  • [Presentation] Development of novel in vitro diagnostics to predict the efficacy of anti-EGFR treatment based on DNA methylation status.2019

    • Author(s)
      4.大内康太,高橋信,沖田啓,坂本康寛,武藤理,天貝賢二,岡田恭穂,大堀久詔,篠崎英司,蒲生真紀夫,石岡千加史
    • Organizer
      第 17 回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03508
  • 1.  ISHIOKA Chikashi (60241577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  高橋 雅信 (00447161)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  高橋 信 (20431570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  西條 憲 (70636729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  唐澤 秀明 (30547401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  大坪 和香子 (00598203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  前川 正充 (70572882)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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