Ido Yasuo 井戸康夫

Researcher Number	50814133
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 内科学, 助教
Affiliation (based on the past Project Information) *help	2018 – 2024: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 内科学, 助教
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator LKB1 / 腎不全 / 肥満 / 腎糸球体病変 / 高脂肪食 / AMP キナーゼ / 糖尿病 / C-ペプチド / Erf2 / type 2 diabetes … More / High fat diet / Nrf2 / Autophagy / Doxorubicin / C-peptide … More Except Principal Investigator 血管内皮機能 / transcriptome / endothelial cell / 血管内皮機能障害 / 糖尿病 / パルミチン酸 / O-GlcNAc / 血管 / 動脈硬化 / Palmitic acid / O-GlcNAｃ / 血管内皮細胞 / ２型糖尿病 / 脂質代謝 / 臓器連関 / 酸化ストレス / 脂肪分化 / 肥満 / 血管内皮障害 / インスリン / 2型糖尿病 / 腎機能障害 / 活性酸素種 / 内皮依存性血管拡張 / インスリン抵抗性 / メタボリックシンドローム / 一酸化窒素 / ミトコンドリア / 脂肪肝 / 異所性脂肪沈着 / Insulin / ERK2 / 脂肪細胞 Less

Elucidation of the relationship between diabetes and chronic vascular inflammation by transcriptome analysis using the great saphenous vein
- Principal Investigator
  
  眞崎暢之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Defense Medical College
肥満関連腎症の新たなマウスモデルを使った成因と遺伝子治療の研究Principal Investigator
- Principal Investigator
  
  井戸康夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  National Defense Medical College
Mechanism of palmitic acid-induced diabetic endothelial dysfunction via O-GlcNAc
- Principal Investigator
  
  MASAKI NOBUYUKI
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Defense Medical College
Eucidation of signaling by Cpeptide and application for cardiovascular diseasePrincipal Investigator
- Principal Investigator
  
  Ido Yasuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Defense Medical College
Role of ERK2 in Ectopic Fat deposition and Cardiovascular Complications of Type II Diabetes
- Principal Investigator
  
  Adachi Takeshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Defense Medical College

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] A Low Arginine/Ornithine Ratio is Associated with Long-Term Cardiovascular Mortality2023
- Author(s)
  Ishinoda Yuki、Masaki Nobuyuki、Hitomi Yasuhiro、Taruoka Akira、Kawai Akane、Iwashita Midori、Yumita Yusuke、Kagami Kazuki、Yasuda Risako、Ido Yasuo、Toya Takumi、Ikegami Yukinori、Namba Takayuki、Nagatomo Yuji、Miyazaki Koji、Takase Bonpei、Adachi Takeshi
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 30 Issue: 10 Pages: 1364-1375
- DOI
  10.5551/jat.63779
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2023-10-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08503
[Journal Article] Association of serum nitric oxide metabolite level with mortality in patients undergoing coronary angiography2022
- Author(s)
  Namba Takayuki、Masaki Nobuyuki、Hitomi Yasuhiro、Ishinoda Yuki、Iwashita Midori、Yumita Yusuke、Kagami Kazuki、Yasuda Risako、Ikegami Yukinori、Toya Takumi、Nagatomo Yuji、Takase Bonpei、Soejima Kyoko、Adachi Takeshi
- Journal Title
  
  Journal of Cardiology
  
  Volume: 80 Issue: 6 Pages: 578-584
- DOI
  10.1016/j.jjcc.2022.07.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08503
[Journal Article] Effectiveness of the d-ROMs oxidative stress test to predict long-term cardiovascular mortality.2022
- Author(s)
  Hitomi Y, Masaki N, Ishinoda Y, Ido Y, Iwashita M, Yumita Y, Kagami K, Yasuda R, Ikegami Y, Toya T, Namba T, Nagatomo Y, Takase B, Adachi T
- Journal Title
  
  Int J Cardiol
  
  Volume: 354 Pages: 43-47
- DOI
  10.1016/j.ijcard.2022.03.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815, KAKENHI-PROJECT-20K08503
[Journal Article] Development of a high-yield, high-quality purification process for adeno-associated virus vectors that can be used in vivo without ultracentrifugation: Application to a lung endothelial cell-targeted adeno-associated virus2022
- Author(s)
  Shiraishi, Y, Adachi, T, Cacicedo, J, Ido Y.
- Journal Title
  
  FASEB Journal
  
  Volume: 36 Issue: 12
- DOI
  10.1096/fj.202200840rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08371, KAKENHI-PROJECT-20K17204
[Journal Article] Deletion of Superoxide Dismutase 1 Blunted Inflammatory Aortic Remodeling in Hypertensive Mice under Angiotensin II Infusion2021
- Author(s)
  Shiraishi Yasunaga、Ishigami Norio、Kujiraoka Takehiko、Sato Atsushi、Fujita Masanori、Ido Yasuo、Adachi Takeshi
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 3 Pages: 471-471
- DOI
  10.3390/antiox10030471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17204, KAKENHI-PROJECT-18H02815
[Journal Article] Activation of LKB1 rescues 3T3-L1 adipocytes from senescence induced by Sirt1 knock-down: a pivotal role of LKB1 in cellular aging2020
- Author(s)
  Fan Lan, Yan Lin, Zhenfeng Gao, Jose M Cacicedo, Karen Weikel, Yasuo Ido
- Journal Title
  
  Aging (Albany NY)
  
  Volume: 12 Issue: 19 Pages: 18942-18956
- DOI
  10.18632/aging.104052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08120
[Journal Article] Impaired nicotinamide adenine dinucleotide (NAD) metabolism in diabetes and diabetic tissues: Implications for nicotinamide‐related compound treatment.2020
- Author(s)
  Fan Lan, Jose M Cacicedo, Yasuo Ido
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 11 Issue: 6 Pages: 250-260
- DOI
  10.1111/jdi.13303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08120
[Journal Article] Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study2020
- Author(s)
  Toya Takumi、Ito Kei、Kagami Kazuki、Osaki Ayumu、Sato Atsushi、Kimura Toyokazu、Horii Shunpei、Yasuda Risako、Namba Takayuki、Ido Yasuo、Nagatomo Yuji、Hayashi Katsumi、Masaki Nobuyuki、Yada Hirotaka、Adachi Takeshi
- Journal Title
  
  IJC Heart & Vasculature
  
  Volume: 26 Pages: 100437-100437
- DOI
  10.1016/j.ijcha.2019.100437
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815
[Journal Article] The association of insulin-induced eNOS activation in freshly isolated arterial endothelial cells with cardio-ankle vascular index2019
- Author(s)
  5)Nobuyuki Masaki, Yasuo, Ido, Adachi T et al.
- Journal Title
  
  JAHA
  
  Volume: 19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02815
[Journal Article] Endothelial Insulin Resistance of Freshly Isolated Arterial Endothelial Cells From Radial Sheaths in Patients With Suspected Coronary Artery Disease2019
- Author(s)
  Nobuyuki Masaki, Yasuo Ido, Toshiyuki Yamada, Youhei Yamashita, Takumi Toya, Bonpei Takase, Naomi M. Hamburg, Takeshi Adachi
- Journal Title
  
  Journal of American Heart Association
  
  Volume: 8 Issue: 6
- DOI
  10.1161/jaha.118.010816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09565, KAKENHI-PROJECT-18H02815
[Journal Article] Production of adeno-associated virus vectors for in vitro and in vivo applications2019
- Author(s)
  Kimura Toyokazu、Ferran Beatriz、Tsukahara Yuko、Shang Qifan、Desai Suveer、Fedoce Alessandra、Pimentel David Richard、Luptak Ivan、Adachi Takeshi、Ido Yasuo、Matsui Reiko、Bachschmid Markus Michael
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 13601-13601
- DOI
  10.1038/s41598-019-49624-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Journal Article] Computed tomography-measured pulmonary artery to aorta ratio and EUTOS score for detecting dasatinib-induced pulmonary arterial hypertension2019
- Author(s)
  Toya Takumi、Nagatomo Yuji、Kagami Kazuki、Yukino Midori、Yasuda Risako、Namba Takayuki、Ido Yasuo、Kobayashi Shinichi、Masaki Nobuyuki、Yada Hirotaka、Kimura Fumihiko、Adachi Takeshi
- Journal Title
  
  The International Journal of Cardiovascular Imaging
  
  Volume: 35 Issue: 8 Pages: 1435-1442
- DOI
  10.1007/s10554-019-01548-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815
[Journal Article] Preserved Vasoconstriction and Relaxation of Saphenous Vein Grafts Obtained by a No-Touch Technique for Coronary Artery Bypass Grafting2018
- Author(s)
  Yamada T, Adachi T, Ido Y, Masaki N, Toya T, Uchimuro T, Nishigawa K, Suda H, Osako M, Yamazaki M, Takanashi S, Shimizu H
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 1 Pages: 232-238
- DOI
  10.1253/circj.CJ-18-0714
- NAID
  130007550528
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2018-12-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09565, KAKENHI-PROJECT-18H02815
[Presentation] SM22α-Cre Driven Extracellular Signal-Regulated Kinase 2 Knockout Mice Causes Cardiac Failure and Vascular Dysfunction.2021
- Author(s)
  Kazuki Kagami, Yusuke Yumita, Midori Iwashita, Yuki Ishinoda, Takayuki Namba, Takumi Toya, Risako Yasuda, Yukinori Ikegami, Nobuyuki Masaki, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  The 5th JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] SERCA2 C674S Modification Leads to Ca2+ Mishandling with Hypertrophy in Right Ventricular Exposed to Hypoxia2021
- Author(s)
  Kazuki Kagami, Kei Ito, Hirotaka Yada, Yusuke Yumita, Midori Iwashita, Yuki Ishinoda, Takayuki Namba, Takumi Toya, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  American Heart Association Scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Prognostic Value of Diffusion-Weighted Cardiac Magnetic Resonance Imaging in Hospitalized Heart Failure Patients2021
- Author(s)
  Kazuki Kagami, Takumi Toya, shunpei Kuwaki, Atsushi Sato, Yusuke Yumita, Ayumu Osaki, Midori Iwashita, Risako Yasuda, Yukinori Ikegami, Takayuki Namba, Nobuyuki Masaki, Yuji Nagatomo , Katsumi Hayashi, Takeshi Adachi
- Organizer
  American Heart Association Scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Contributed to the Development of Pulmonary Arterial Hypertension in Mice Through the Impairment of Endothelial Nitric Oxide Synthase Function2021
- Author(s)
  Yusuke Yumita, Kazuki Kagami, Yuki Ishinoda, Midori Iwashita,Takumi Toya, Yukinori Ikegami, Takayuki Namba, Nobuyuki Masaki, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  American Heart Association Scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Contributed to the Development of Pulmonary Arterial Hypertension in Mice Through the Impairment of Endothelial Nitric Oxide Synthase Function2021
- Author(s)
  Yusuke Yumita, Kazuki Kagami, Yuki Ishinoda, Midori Iwashita, Takumi Toya, Yukinori Ikegami, Takayuki Namba, Nobuyuki Masaki, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  日本循環器学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] SERCA2 C674S heterozygote knock-in mice revealed Ca2+ mishandling and hypertrophy 　　in right ventricular under hypoxia2021
- Author(s)
  Kazuki Kagami, Kei Ito, Hirotaka Yada, Yusuke Yumita,Yuki Ishinoda, Takayuki Namba, Takumi Toya, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  日本循環器学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Loss of Extracellular Signal-Regulated Kinases 2 Using SM22α-Cre Driver Causes Cardiac Failure and Vascular Dysfunction、American Heart Association Scientific sessions,2021
- Author(s)
  Kazuki Kagami, Yusuke Yumita, Midori Iwashita, Yuki Ishinoda, Takayuki Namba, Takumi Toya, Yasuo Ido, Yuji Nagatomo, Takeshi Adachi
- Organizer
  American Heart Association Scientific sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02815
[Presentation] Adipose extracellular signal-regulated kinase 2 protected from endothelial dysfunction and the oxidative stress of perivascular adipose tissue in obese mice2020
- Author(s)
  A Osaki , Y Sato , S Endo , K Ito, K Kagami , Y Yumita , Y Ishinoda , T Toya , Y Ido , T Namba , T Adachi
- Organizer
  The 4th JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-18H02815

1. Adachi Takeshi (50231931)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. MASAKI NOBUYUKI (00364795)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 菱木貴子 (10338022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 佐藤泰司 (10505267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 高瀬凡平 (50518214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 堤浩二 (00338071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大澤有紀子 (00816928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 石田治 (20365266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小林真一 (50724655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 真崎暢之

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. 難波貴之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 白石安永

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ido Yasuo 井戸 康夫

Research Projects

Research Products

Co-Researchers

Elucidation of the relationship between diabetes and chronic vascular inflammation by transcriptome analysis using the great saphenous vein

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肥満関連腎症の新たなマウスモデルを使った成因と遺伝子治療の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of palmitic acid-induced diabetic endothelial dysfunction via O-GlcNAc

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Eucidation of signaling by Cpeptide and application for cardiovascular diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of ERK2 in Ectopic Fat deposition and Cardiovascular Complications of Type II Diabetes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A Low Arginine/Ornithine Ratio is Associated with Long-Term Cardiovascular Mortality2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Association of serum nitric oxide metabolite level with mortality in patients undergoing coronary angiography2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effectiveness of the d-ROMs oxidative stress test to predict long-term cardiovascular mortality.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a high-yield, high-quality purification process for adeno-associated virus vectors that can be used in vivo without ultracentrifugation: Application to a lung endothelial cell-targeted adeno-associated virus2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deletion of Superoxide Dismutase 1 Blunted Inflammatory Aortic Remodeling in Hypertensive Mice under Angiotensin II Infusion2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of LKB1 rescues 3T3-L1 adipocytes from senescence induced by Sirt1 knock-down: a pivotal role of LKB1 in cellular aging2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired nicotinamide adenine dinucleotide (NAD) metabolism in diabetes and diabetic tissues: Implications for nicotinamide‐related compound treatment.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The association of insulin-induced eNOS activation in freshly isolated arterial endothelial cells with cardio-ankle vascular index2019

Author(s)

Journal Title

Ido Yasuo 井戸康夫

[Presentation] SERCA2 C674S heterozygote knock-in mice revealed Ca2+ mishandling and hypertrophy 　　in right ventricular under hypoxia2021