Kasahara Tadashi 笠原忠

… Alternative Names

KASAHARA Tadashi 笠原忠

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Researcher Number	60049096
Other IDs
External Links
Affiliation (Current)	2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2014: 慶應義塾大学, 薬学部, 名誉教授 2008 – 2013: Keio University, 薬学部, 教授 1995 – 2007: 共立薬科大学, 薬学部, 教授 2000: 共立薬科大学, 薬学部・病態薬学系・生化学教室, 教授 1999: 共立薬科大学, 生化学教室, 教授 … More 1997: Kyoritsu College of Pharmacy, Dept.of Biochemistry, Professor 1993 – 1994: 自治医大, 医学部, 助教授 1993: 自治医科大学, 医学部/助教授 1989 – 1993: Dept. of Medicine, Jichi Medical School, Assistant Professor., 医学部, 助教授 1990: 自治医科大学, 医動物免疫学, 助教授 1989: 自治医大, 医動物免疫学, 助教授 1988: 自治医大, 医学部, 助教授 1987: 自治医科大学, 医学部, 助教授 1986: JICHI MEDICAL SCHOOL, ASSOCIATE PROFESSOR, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Immunology / Biological Sciences / Hematology Except Principal Investigator 応用薬理学・医療系薬学 / Immunology / Biological pharmacy / Laboratory medicine / Applied pharmacology / Hematology / Biological pharmacy
Keywords	Principal Investigator IL-8 / TRAF6 / MS / MALDI-TOF / DNA microarray / DNAマイクロアレー / 接着斑キナーゼ / anti-apoptosis / PI3-kinase / focal adhesion kinase (FAK) … More / アポトーシス / 酸化ストレス / シグナル伝達機構 / cAMP / V617F変異体 / 薬剤耐性機構 / アデノウイルスベクター / 抗アポートシス作用 / 接着斑キナーゼFAK / アポートシス / MCAF(MCP-1) / 炎症性サイトカイン / IL1 receptor / Western blotting / Monoclonal antibody / Interleukin 1 (IL1) / IL1リセプター / 酵素免疫測定法 / モノクロナル抗体 / インターロイキン1 / Apoptosis / Focal adhesion kinase / NF-kB / TNF signaling / FAK過剰発現 / FAK / NF-κB / TNFシグナル / glutathione peroxidase / protein kinase C / oxidative-stress / タンパク質のプロファイリング / レドックス制御 / 2次元電気泳動 / HL-60 / シグナル分子 / グルタチオンベルオキシダーゼ / プロテインキナーゼ-C / PI3-キナーゼ / DNAマイクロレー / 接着班キナーゼ(FAK) / 抗アポトーシス / caspase family / survival pathway / oxidative stress / signal trasduction / apoptosis induction / 抗アポトーシス作用 / アポトーシス誘導阻止因子 / 抗アボートシス作用 / in vivo effect / neutrophil chemotaxis / gene regulation / MCAF / Inflammatory cytokine / ケモタキシス / 1L-8 / 1L-6 / 尿中サイトカイン / 好中球ケモタクシス / signal transduction / astrocytes / IL-6 / IL-1 / コレラトキシン / IL6 / IL1 / 情報伝達機構 / アストロサイト / ILー8 / ILー6 / ILー1 / 国際情報交換 / FANCC / ODC / JAK2V617F / MPN治療薬 / ODC阻害剤 / c-Mycシグナル / STAT5の活性化 / 骨髄増殖性腫瘍 / JAK2シグナル解析 / フラーレン誘導体 / ファンコニタンパク質 / 抗がん剤耐性 / オルニチンデカルボキシラーゼ / c-Myc活性化 / JAK2 変異体 / JAK/STATシグナル系 / 真性赤血球増加症 / チロシンリン酸化 / JAK2 / 接着分子FAK / NF-κB阻害作用 / GSK-3βのリン酸化 / 抗アポトーシス因子 / メラノーマ細胞 / GSK-3β / c-Myc / STAT5 / JAK2シグナル伝達 / JAK2点変異V617F / リコカルコンA / 腫瘍形成能 / STAT5の恒常的な活性化 / Epoシグナル / JAK2 V617F変異体 / JAKキナーゼ / 接着班キナーゼFAK / TNF誘導サイトカイン遺伝子 / サイトカイン産生 / 細胞障害性の感受性 / FAK欠損マウス由来MEF / TRAF6欠損マウス由来MEF / TRAF6遺伝子欠損 / NF-KB活性化 / ST2 / TNFシグナリング / TNF受容体 / TRAF6 遺伝子欠損 / NF-κB 活性化 / IL-33 / セレコキシブ / TNF シグナリング / TNF 受容体 / 抗がん剤 / グリオーマ細胞 / 好酸球 / 単球走化因子 / 核内転写因子 / ミエローマ / 血管内皮細胞 / ケモカイン / インターロイキン-8 / CD34 / RTーPCR / ステムセルファクタ-(SCF) / cーkit … More Except Principal Investigator 接着斑キナーゼ / apoptosis / PI3-kinase / FAK / glioma / survival / アポトーシス / Akt / MCAF / インターロイキン8 / IgA / caspase-8 / TRAIL / Bcl-2 / PKC / NFkB / NF-kB / IAP / MCP-1 / 好中球 / ケモカイン / cytokine / 転移 / Enzyme immunoassay / Multiple myeloma / alpha_1-microglobulin / Subclass / Protein A / IgG / α鎮(α-chain) / IgA2 / IgA1 / 選択的IgA欠損症 / α_1ーマイクログロブリン / 酵素免疫測定法 / 多発性骨髄腫 / α_1-マイクログロブリン / サブクラス / siRNA / peroxyredoxin / proteome analysis / 2D-PAGE / focal adhesion kinase / hsp70 / Src kinase / PHGPx / glutathione reductase / thioredoxin reductase / peroxyredoxin 2 / - / FAK- / sp1 / FAK knockout / SP1 / TNF / MS / MALDI-TOF / 抗アポトーシス / Caspase / ER stress / Oxidative stress / Focal adhesion kinase (FAK) / Neuronal cell death / 神経突起伸長 / caspase / カスパーゼ / 小胞体ストレス / 酸化ストレス / 神経細胞死 / cyclin D3 / 還元酵素 / PTEN / カスパーゼ-6 / アデノウイルス / Y397F変異体 / Bcl2 / DNAチップ / CDK / cyclinD3 / PI_3-kinase / NFκB / 脳腫瘍細胞 / サバイバルシグナル / renal diseases / interferon (INF)-γ / angiogenesis / macrophage inflammatory protein (MIP)-1α / macrophage / neutrophil / monocyte chemoattractant protein-1 (MCP-1) / Interleukin-8 (IL-8) / IL-10 / IL-8 / MIP-2 / エオタキシン / AP-1 / NF-κB / 腎疾患 / インターフェロンγ / 血管新生 / MIP-1α / マクロファージ / 単球走化因子(MCP-1) / Translocation / Intracellular pH / Cytoskeleton / Superoxide / Okadaic acid / Opsonized zymosan / Phagocytes / Cofilin / オカダ酸 / F-アクチン / 細胞内pH変化 / 共焦点レーザー走査蛍光顕微鏡 / 細胞内pH / トランスロケーション / 脱リン酸化反応 / アクチン結合蛋白 / オプソニン化ザイモザン / コフィリン / 食細胞 / receptor / HIV infection / inflammation / monocytes / neutrophils / interleukin-8 / Chemokine / 急性呼吸窮迫症候群 / 糸球体腎炎 / 単球走活性化因子 / レセプター / HIV感染 / 炎症反応 / 単球 / 単球走化活性化因子 / Transcription factor / Charcot-Leyden crystal / Eosinophil peroxidase / eosinophil / GATA-1 / 好酸球ペルオキシダーゼ / 転写因子 / 遺伝子制御 / 好酸球 / pathophysialogical roles / gene expression / receptors / structural analysis / interleukin 8 / Leukocyte Chemotactic factors / 前臨床実験 / 構造と機能 / McAF / インタ-ロイキン8 / 病態生理作用 / 遺伝子発現 / 受容体 / 構造解析 / サイトカイン / 白血球走化性因子 / amniotic fluid / signal transduction / cell cycle / myeloid leukemia cell / myeloma cell / growth regulation / interleukin 1 / インタ-ロイキン6 / プロスタグランジンE_2 / 増殖分化 / インタ-ロイキン1 / 細胞周期 / 羊水 / プロスタグランジン / cAMP / 骨髄性白血病細胞 / 増殖・分化 / インタ-ロイキシン1 / B16BL-6 / metastasis / B16BL6 / B16F10 / melanoma / PLP2 / プロテオリピドプロテイン / メラノーマ Less

Investigation of JAK/STAT signalling and development of new reagents regulating JAK/STAT pathwaysPrincipal Investigator
- Principal Investigator
  
  KASAHARA Tadashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
Investigation of abnormal cytokine signaling and the development of the drugs modulating these signalingPrincipal Investigator
- Principal Investigator
  
  KASAHARA Tadashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
Analysis of melanoma metastasis gene, proteolipid protein
- Principal Investigator
  
  SONODA Yoshiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
Role of TNF receptor-related factor 6(TRAF6) in the apoptosis induction and cytokine receptor signalingPrincipal Investigator
- Principal Investigator
  
  KASAHARA Tadashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
  Kyoritsu University of Pharmacy
Basic approaches for the development of immunomodulatory and anti-inflammatory drugs acting on the signaling moleculesPrincipal Investigator
- Principal Investigator
  
  KASAHARA Tadashi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoritsu University of Pharmacy
Proteome analysis of anti-apoptotic proteins in FAK-overexpressing cells
- Principal Investigator
  
  SONODA Yoshiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoritsu University of Pharmacy
STUDY ON THE NEW ANTI-APOPTOTIC MOLECULES ANALYZED BY THE DNA MICROARRAY METHODSPrincipal Investigator
- Principal Investigator
  
  KASAHARA Tadashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYORITSU WOMEN'S UNIVERSITY
Regulation of cell death and neurite outgrowth by overexpressed focal adhesion kinase in rat pheochrome cytoma PC 12
- Principal Investigator
  
  YOKOTA Eriko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoritsu University of Pharmacy
Focal Adhesion Kinase as a Potential Target for The Therapy of The Human Glioma
- Principal Investigator
  
  SONODA Yoshiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoritsu College of Pharmacy
接着斑キナーゼの抗アポトーシス作用とその機序の解析Principal Investigator
- Principal Investigator
  
  笠原忠
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoritsu University of Pharmacy
Role of Anti-Apoptic Aaction of Focal Adhesion Kinase (FAK)Principal Investigator
- Principal Investigator
  
  KASAHARA Tadashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoritsu College of Pharmacy
FOCAL ADHESION KINASE AS A POTENTIAL TARGET FOR THE THERAPY OF THE HUMAN GLIOMA THE HUMAN GLIOMA
- Principal Investigator
  
  SONODA Yoshiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYORITSU COLLEGE OF PHARMACY
Pathophyiological and immunopharmacological studies on chemokines and their receptors
- Principal Investigator
  
  MUKAIDA Naofumi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Immunology
- Research Institution
  Kanazawa University
Pathophysiological and pharmacological studies on chemokines
- Principal Investigator
  
  MATSUSHIMA Kouji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Immunology
- Research Institution
  University of Tokyo
Studies on roles of cofilin (actin/PIP2-binding protein) in activation of phagocytes
- Principal Investigator
  
  SUZUKI Kazuhiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences (NIHS)
炎症性サイトカインとそのレセプター遺伝子発現機序の解析とその制御Principal Investigator
- Principal Investigator
  
  笠原忠
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoritsu University of Pharmacy
The regulation of gene expression for the genes associated with eosinophils.
- Principal Investigator
  
  YAMAGUCHI Yuji
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Expression and Regulation of Inflammatory Cytokine Genes In Vitro and In VivoPrincipal Investigator
- Principal Investigator
  
  KASAHARA Tadashi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Jichi Medical School, Department of Medicine Grant-in-Aid for Scientific Research(C)
ヒト純化造血幹細胞の増殖・分化に対するcーkitおよびcーkitリガンドの作用Principal Investigator
- Principal Investigator
  
  笠原忠
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Basic and preclinical experiments of IL 8 and MCAF
- Principal Investigator
  
  MATSUSHIMA Kouji, 松島網治
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Cancer Research Institute, Kanazawa University
Study on the IL-1-Mediated Signal Transduction SystemPrincipal Investigator
- Principal Investigator
  
  KASAHARO Tadashi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Jichi Medical School
Study on the Interleukin 1 Growth-Regulatory Activity.
- Principal Investigator
  
  ONOZAKI Kikuo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Fac of Pharmaceutical Sciences, Nagoya City University
A Fundamental Study on Immunoglobulin subclass and its clinical application.
- Principal Investigator
  
  KAWAI Tadahi
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Jichi Medical School
IMMUNOLOGICAL AND IMMUNOCHEMICAL ANALYSIS OF HUMAN INTERLEUKIN 1 AND ITS RECEPTORPrincipal Investigator
- Principal Investigator
  
  KASAHARA TADASHI
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  JICHI MEDICAL SCHOOL

[Book] 臨床免疫・アレルギー科(総説、ケモカイン:エオタキシン-1/CCL11)2012
- Author(s)
  笠原忠
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21590072
[Book] 「疾病と病態」改訂第3版2012
- Author(s)
  笠原忠
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21590072
[Book] 臨床免疫・アレルギー科(総説、ケモカイン:エオタキシンー1/CCL11)2012
- Author(s)
  笠原忠
- Publisher
  科学評論社(印刷中)
- Data Source
  KAKENHI-PROJECT-21590072
[Book] ヒューマニズム薬学入門(笠原忠、越前宏俊共編)2012
- Author(s)
  笠原忠
- Publisher
  培風館
- Data Source
  KAKENHI-PROJECT-21590072
[Book] 「疾病と病態」改訂第3版、(分担,免疫疾患と炎症)(監修豊島聡)2012
- Author(s)
  笠原忠
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21590072
[Book] ヒューマニズム薬学入門2012
- Author(s)
  笠原忠
- Publisher
  培風館
- Data Source
  KAKENHI-PROJECT-21590072
[Book] L-33レセプターのシグナル伝達、臨床免疫・アレルギー科2011
- Author(s)
  笠原忠、多胡めぐみ
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21590072
[Book] 臨床免疫・アレルギー科(解説、IL-33レセプターのシグナル伝達)2011
- Author(s)
  笠原忠、多胡めぐみ
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21590072
[Book] IL-33レセプターのシグナル伝達2010
- Author(s)
  笠原忠、多胡めぐみ
- Publisher
  臨床免疫・アレルギー科、科学評論社
- Data Source
  KAKENHI-PROJECT-21590072
[Book] 炎症・再生医学事典2009
- Author(s)
  笠原忠、多胡めぐみ
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-21590072
[Book] からだの科学2009
- Author(s)
  笠原忠
- Publisher
  日本評論社
- Data Source
  KAKENHI-PROJECT-21590072
[Book] 創薬における薬剤師の役割、からだの科学(増刊)2009
- Author(s)
  笠原忠
- Publisher
  日本評論社
- Data Source
  KAKENHI-PROJECT-19590075
[Book] 創薬における薬剤師の役割(増刊)2009
- Author(s)
  笠原忠
- Publisher
  からだの科学
- Data Source
  KAKENHI-PROJECT-19590075
[Book] スタンダード免疫学(改訂3版)2009
- Author(s)
  小林芳郎, 笠原忠, 片桐拓也, 渡辺直子
- Total Pages
  190
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-19590075
[Book] 免疫のしくみ・アレルギー免疫疾患とその服薬指導2008
- Author(s)
  笠原忠、大川智子
- Publisher
  共立薬科大学, 東京
- Data Source
  KAKENHI-PROJECT-19590075
[Book] スタンダード免疫学(小林芳郎編)(改訂第3版)2008
- Author(s)
  笠原忠
- Publisher
  丸善, 東京
- Data Source
  KAKENHI-PROJECT-19590075
[Book] 生体防御医学事典「TNFαの生理活性と病態」2007
- Author(s)
  市川大樹, 笠原忠
- Publisher
  朝倉書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Book] 生体防御医学事典「TNFαの生理活性と病態」2007
- Author(s)
  市川大樹, 笠原忠
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-16390024
[Book] 疾病と病態生理改訂第2版、「炎症疾患と炎症」2006
- Author(s)
  笠原忠
- Publisher
  南江堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Book] TGN1412事件とは何か?「TGN1412事件と今後の課題」2006
- Author(s)
  山崎恒義, 笠原忠
- Publisher
  臨床評価刊行会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Book] 予防医学事典;(炎症・免疫、アレルギー、ワクチン 4.炎症)(松島綱治ら編)2005
- Author(s)
  笠原忠
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Study of Cytokine Signaling: The Quest for Immunomodulatory Drugs Interacting with Cytokine Production and Activity2015
- Author(s)
  Kasahara T.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 135 Issue: 3 Pages: 431-447
- DOI
  10.1248/yakushi.14-00237
- NAID
  130004756509
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2015-03-01
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590091
[Journal Article] NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β2015
- Author(s)
  Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 8 Pages: 5065-5077
- DOI
  10.1074/jbc.m114.603217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146
[Journal Article] Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway.2015
- Author(s)
  Funakoshi-Tago M, Okamoto K, Izumi R, Tago K, Yanagisawa K, Narukawa Y, Kiuchi F, Kasahara T, Tamura H.
- Journal Title
  
  Int. Immunopharmacol.
  
  Volume: 25 Issue: 1 Pages: 189-198
- DOI
  10.1016/j.intimp.2015.01.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500996, KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-25460073, KAKENHI-PROJECT-26440062
[Journal Article] Dietary deprivation of each essential amino acid induces differential systemic adaptive responses in mice.2014
- Author(s)
  Kamata S, Yamamoto J, Kamijo K, Ochiai T, Morita T, Yoshitomi Y, Hagiya Y, Kubota M, Ohkubo R, Kawaguchi M, Himi T, Kasahara T, Ishii I.
- Journal Title
  
  Mol Nutr Food Res.
  
  Volume: 58 Issue: 6 Pages: 1309-1321
- DOI
  10.1002/mnfr.201300758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25460072
[Journal Article] Effect of chemical modification on the ability of pyrrolidinium fullerene to induce apoptosis of cells transformed by JAK2 V617F mutant.2014
- Author(s)
  Funakoshi-Tago M, Tsukada M, Watanabe T, Mameda Y, Tago K, Ohe T, Nakamura S, Mashino T, Kasahara T.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 20 (1) Issue: 1 Pages: 258-263
- DOI
  10.1016/j.intimp.2014.02.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23570166, KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-25460073, KAKENHI-PROJECT-26440062
[Journal Article] Critical roles of Myc-ODC axis in the cellular transformation induced by myeloproliferative neoplasm-associated JAK2 V617F mutant.2013
- Author(s)
  Funakoshi-Tago M, Sumi K, Kasahara T, Tago K.
- Journal Title
  
  PLoS One.
  
  Volume: 8 (1) Issue: 1 Pages: e52844-e52844
- DOI
  10.1371/journal.pone.0052844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570166, KAKENHI-PROJECT-23790096, KAKENHI-PROJECT-24590091
[Journal Article] Critical role of FANCC in JAK2 V617F mutant-induced resistance to DNA cross-linking drugs.2013
- Author(s)
  Ueda F, Sumi K, Tago K, Kasahara T, Funakoshi-Tago M
- Journal Title
  
  Cell Signal
  
  Volume: 25 (11) Issue: 11 Pages: 2115-2124
- DOI
  10.1016/j.cellsig.2013.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570166, KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-25460073
[Journal Article] Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine γ-lyase, an animal model of cystathioninuria2012
- Author(s)
  Yamada H, Akahoshi N, Hagiya Y, Izumi T, Kumagai Y, Kasahara T, Suematsu M, Ishii I., 他7名
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 52(9) Pages: 1716-1726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Reprofiling a classical anthelmintic, pyrvinium pamoate, as an anti-cancer drug targeting mitochondrial respiration.2012
- Author(s)
  Ishii I, Harada Y, Kasahara T.
- Journal Title
  
  Front Oncol.
  
  Volume: 2 Pages: 137-137
- DOI
  10.3389/fonc.2012.00137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590091, KAKENHI-PUBLICLY-23117716
[Journal Article] Pyrvinium pamoate inhibits proliferation of myeloma/erythroleukemia cells by suppressing mitochondrial respiratory complex I and STAT32012
- Author(s)
  Harada Y, Ishii I, Hatake K, Kasahara T.
- Journal Title
  
  Cancer Lett
  
  Volume: 319(1) Pages: 83-88
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Fullerene derivative prevents cellular transformation induced by JAK2 V617F mutant through inhibiting c-Jun N-terminal kinase pathway.2012
- Author(s)
  Funakoshi-Tago M, Nagata T, Tago K, Tsukada M, Tanaka K, Nakamura S, Mashino T, Kasahara T.
- Journal Title
  
  Cell Signal.
  
  Volume: 24 (11) Issue: 11 Pages: 2024-2034
- DOI
  10.1016/j.cellsig.2012.06.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570166, KAKENHI-PROJECT-23790096, KAKENHI-PROJECT-24590091
[Journal Article] Akt activation through the phosphorylation of erythropoietin receptor attyrosine 479 is required for myeloproliferative disorder-associated JAK2V617F mutant-induced cellular transformation.2011
- Author(s)
  Kamishimoto J, Tago K, Kasahara T, Funakoshi-Tago M.
- Journal Title
  
  Cell Signal.
  
  Volume: 23(5) Pages: 849-856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin.2011
- Author(s)
  Funakoshi-Tago M, Nakamura K, Tago K, Mashino T, Kasahara T.
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Akt activation through the ph osphorylation of erythropoietin receptor at tyr osine 479 is required for myeloproliferative d isorder-associated JAK2 V617F mutant-induce d cellular transformation2011
- Author(s)
  Kamishimoto J, Tago K, Kasahara T, Fun akoshi-Tago M.
- Journal Title
  
  Cell Signal
  
  Volume: 23(5) Pages: 849-856
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] JAK2 is an important signal transducer in IL-33-induced NF-χB activation2011
- Author(s)
  Funakoshi-Tago M, Tago K, Sato Y, Tominaga S, Kasahara T
- Journal Title
  
  Cell Signaling
  
  Volume: 23(2) Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin2011
- Author(s)
  Funakoshi-Tago M, Nakamura K, Tago K, Mashino T, Kasahara T
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 11(9) Pages: 1150-1159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Anti-inflammatory ac tivity of structurally related flavonoids, Apige nin, Luteolin and Fisetin2011
- Author(s)
  Funakoshi-Tago M, Nakamura K, Tago K, MashinoT, Kasahara T.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 11(9) Pages: 1150-1159
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Temporal expression and mitochondrial localization of a Foxp2 isoform lacking the forkhead domain in developing Purkinje cells2011
- Author(s)
  Tanabe Y, Fujiwara Y, Matsuzaki A, Fujita E, Kasahara T, Yuasa S, Momoi T
- Journal Title
  
  J Neurochem
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Aurora kinase A critically contributes to the resistance to anti-cancer drug cisplatin in JAK2 V617F mutant-induced transformed cells2011
- Author(s)
  Sumi K, Tago K, Kasahara T, Funakoshi-Tago M.
- Journal Title
  
  FEBS Lett
  
  Volume: 585(12) Pages: 1884-1890
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] JAK2 is an important signal transducer in IL-33-induced NF-κB activation2011
- Author(s)
  Funakoshi-Tago M, Tago K, Sato Y, Tominaga S, Kasahara T.
- Journal Title
  
  Cell Signal
  
  Volume: 23(2) Pages: 263-270
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] JAK2 is an important signal transducer in IL-33-induced NF-κB activation.2011
- Author(s)
  Funakoshi-Tago M, Tago K, Sato Y, Tominaga S, Kasahara T.
- Journal Title
  
  Cell Signal.
  
  Volume: 23(2) Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Akt activation through the phosphorylation of erythropoietin receptor at tyrosine 479 is required for myeloproliferative disorder-associated JAK2 V617F mutant-induced cellular transformation2011
- Author(s)
  Kamishimoto J, Tago K, Kasahara T, Funakoshi-Tago M
- Journal Title
  
  Cell Signaling
  
  Volume: 23(5) Pages: 849-856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F mutant.2010
- Author(s)
  Funakoshi-Tago M, Tago K, Abe M, Sonoda Y, Kasahara T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285(8) Pages: 5296-5307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] The fixed structure of licochalcone A by alpha, beta-unsaturated ketone is necessary for anti-inflammatory activity through the inhibition of NF-kappaB activation2010
- Author(s)
  Funakoshi-Tago M, Nakamura K, Tsuruya R, Hatanaka M, Mashino T, Sonoda Y, Kasahara T
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 10 Pages: 562-571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] The fixed structure of Licochalcone A by alpha, beta-unsaturated ketone is necessary for anti-inflammatory activity through the inhibition of NF-kB activation2010
- Author(s)
  Funakoshi-Tago M, Nakamura K, Tsuruya R, Hatanaka M, Mashino T, Sonoda Y, Kasahara T.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 10(5) Pages: 562-571
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Licochalcones suppress degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.2010
- Author(s)
  Tanifuji S, Aizu-Yokota E, Funakoshi-Tago M, Sonoda Y, Inoue H, Kasahara T.
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 10(7) Pages: 769-770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F Mutant2010
- Author(s)
  Funakoshi-Tago M, Tago K, Abe M, Sonoda Y, Kasahara T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 258(8) Pages: 5296-5307
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Proteolipid protein 2 is associated with melanoma metastasis2010
- Author(s)
  Sonoda Y, Warita M, Suzuki T, Ozawa H, Fukuda Y, Funakoshi-Tago M, Kasahara T.
- Journal Title
  
  Oncol Report
  
  Volume: 23(2) Pages: 371-376
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] The fixed structure of Licochalcone A by alpha, beta-unsaturated ketone is necessary for anti-inflammatory activity through the inhibition of NF-kappaB activation.2010
- Author(s)
  Funakoshi-Tago M, Nakamura K, Tsuruya R, Hatanaka M, Mashino T, Sonoda Y, Kasahara T.
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 10(5) Pages: 562-571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F Mutant2010
- Author(s)
  Funakoshi-Tago M, Tago K, Sonoda Y, Kasahara T., 他1名
- Journal Title
  
  J Biol Chem. 258(8)
  
  Pages: 5296-5307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Proteolipid protein 2 is associated with melanoma metastasis2010
- Author(s)
  Sonoda Y, Warita M.Suzuki T, Ozawa H, Fukuda Y, Funakoshi-Tago M, Kasahara T
- Journal Title
  
  Oncol.rep. 23
  
  Pages: 371-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] The fixed structure of Licochalcone A by alpha, beta-unsaturated ketone is necessary for anti-inflammatory activity through the inhibition of NF-κB activation2010
- Author(s)
  Funakoshi-Tago M, Nakamura K, Tsuruya R, Sonoda Y, Kasahara T., 他2名
- Journal Title
  
  Int Immunopharmacol. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Proteolipid protein 2 is associated with melanoma metastasis2010
- Author(s)
  Sonoda Y, Warita M, Suzuki T, Ozawa H, Fukuda Y, Funakoshi-Tago M, Kasahara T.
- Journal Title
  
  Oncol Report 23(2)
  
  Pages: 371-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] The fixed structure of Licochalcone A by alpha, beta-unsaturated ketone is necessary for anti-inflammatory activity through the inhibition of NF-kappaB activation.2010
- Author(s)
  Funakoshi-Tago M, Nakamura K, Tsuruya R, Hatanaka M, Mashino T, Sonoda Y, Kasahara T
- Journal Title
  
  Int Immunopharmacol. Vol.10
  
  Pages: 562-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] Licochalcones suppress degranulation by decreasing the intracellular Ca^<2+> level and tyrosine phosphorylation of ERK in RBL-2H3 cells2010
- Author(s)
  Tanifuji S, Aizu-Yokota E, Funakoshi-Tago M, Sonoda Y, Inoue H, Kasahara T.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 10(7) Pages: 769-770
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Proteolipid protein 2 is associated with melanoma metastasis.2010
- Author(s)
  Sonoda Y, Warita M, Suzuki T, Ozawa H, Fukuda Y, Funakoshi-Tago M, Kasahara T
- Journal Title
  
  Oncol Rep. Vol.23
  
  Pages: 371-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] Licochalcones suppress degranulation by decreasing the intracellular Ca2+ llevel and tyrosine phosphorylation of ERK in RBL-2H3 cells2010
- Author(s)
  Tanifuji S, Aizu-Yokota E, Funakoshi-Tago M, Sonoda Y, Kasahara T
- Journal Title
  
  Int.Immunopharmacol
  
  Volume: 10 Pages: 769-776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear kappaB activation through the direct inhibition of IkappaB kinase complex activation2009
- Author(s)
  Funakoshi-tago M, Tanabe S, Tago K, Itoh H, Mashino T, Sonoda Y, Kasahara T
- Journal Title
  
  Mol.Pharmacol. 76
  
  Pages: 745-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article]2009
- Author(s)
  笠原忠, 多胡めぐみ
- Journal Title
  
  炎症・再生医学事典(松島綱治、西脇徹編)(朝倉書店)
  
  Pages: 52-54
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] The acute lymphoblastic leukemia-associated JAK2 L611S mutant induces tumorigenesis in nude mice2009
- Author(s)
  Funakoshi-Tago M, Tago K, Sumi K, Kasahara T., 他4名
- Journal Title
  
  J Biol Chem. 284(19)
  
  Pages: 12680-12690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation.2009
- Author(s)
  3 Funakoshi-Tago M, Tanabe S, Tago K, Itoh H, Mashino T, Sonoda Y, Kasahara T
- Journal Title
  
  Mol Pharmacol. Vol.76
  
  Pages: 745-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] The acute lymphoblastic leukemia-associated JAK2 L611S mutant induces tumorigenesis in nude mice2009
- Author(s)
  Funakoshi-Tago M, Tago K, Sumi K, Abe M, Aizu-Yokota E, Oshio T, Sonoda Y, Kasahara T.
- Journal Title
  
  J Biol Chem
  
  Volume: 284(19) Pages: 12680-12690
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article]2009
- Author(s)
  笠原忠
- Journal Title
  
  からだの科学(日本評論社)
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] The polycythemia vera-associated Jak2 V617F mutant induces tumorigenesis in nude mice2009
- Author(s)
  Abe M, Funakoshi-Tago M, Tago K, Kamishimoto J, Aizu-Yokota E, Sonoda Y, Kasahara T.
- Journal Title
  
  Int Immunopharmacol(Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kB p65 in LPS signaling pathway2009
- Author(s)
  Furusawa J, Funakoshi-Tago M, Mashino T, Tago K, Sonoda Y, Kasahara T.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 9(4) Pages: 499-507
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] A potently inhibits TNFα-induced NF-κB activation through the direct inhibition of IκB kinase complex activation2009
- Author(s)
  Funakoshi-Tago M, Tanabe S, Sonoda Y, Kasahara T., 他2名
- Journal Title
  
  Mol Pharmacol. 76(4)
  
  Pages: 745-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] TRAF6 negatively regulates TNFa-induced NF-kappaB activation2009
- Author(s)
  Funakoshi-Tago M, Kamada N, Shimizu T, Hashiguchi Y, Tago K, Sonoda Y, Kasahara T.
- Journal Title
  
  Cytokine 45(2)
  
  Pages: 72-9
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaline pathway.2009
- Author(s)
  Furusawa J, Funakoshi-Tago M, Mashino T, Kasahara T., et al.
- Journal Title
  
  Int Immunopharmacol. 9(4)
  
  Pages: 499-507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] A potently inhibits TNFa-induced NF-kB activation through the direct inhibition of IkB kinase complex activation2009
- Author(s)
  Funakoshi-Tago M, Tanabe S, Tago K, Itoh H, Mashino T, Sonoda Y, Kasahara T
- Journal Title
  
  Mol Pharmacol
  
  Volume: 76(4) Pages: 745-753
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation ofNF-kappaBp65 in IPS signaling pathway.2009
- Author(s)
  Furusawa J, Funakoshi-TaM, Mashino T, Tago K, Inoue H, Sonoda Y, Kasahara T.
- Journal Title
  
  Int Immunopharmacol. 9
  
  Pages: 499-507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D,inhibit phosphorylation of NF-kappaBp65 in LPS signaling pathway2009
- Author(s)
  Furusawa J, Funakoshi-Tago M, Mashino T, Tago K, Inoue H, Sonoda Y, Kasahara T.
- Journal Title
  
  Int Immunopharmacol 9(4)
  
  Pages: 499-507
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] TRAF6 negatively regulates TNFalpha-induced NF-kappaB activation.2009
- Author(s)
  Funakoshi-Tago M, Kamada N, Kasahara T., et al.
- Journal Title
  
  Cytokine 45(2)
  
  Pages: 72-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-kappaB p65 phosphorylation at serine 2762009
- Author(s)
  Furusawa J, Funakoshi-Tago M, Tago K, Mashino T, Inoue H, Sonoda Y, Kasahara T.
- Journal Title
  
  Cell Signal
  
  Volume: 21(5) Pages: 778-785
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F mutant2009
- Author(s)
  Funakoshi-tago M, Tago K, Abe M, Sonoda Y, Kasahara T
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 5296-5307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-κB p65 in LPS signaling pathway2009
- Author(s)
  Furusawa J, Funakoshi-Tago M, Mashino T, Tago K, Sonoda Y, Kasahara T.
- Journal Title
  
  Int Immunopharmacol. 9(4)
  
  Pages: 499-507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Licochalcone A significantly suppresses LPS signaling pathway throughthe inhibition of NF-kappaB p65 phosphorylation at serine 276.2009
- Author(s)
  Furusawa JI, Funakoshi-TagoM, Kasahara T., et al.
- Journal Title
  
  Cell Signaling 21(5)
  
  Pages: 778-785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] The polycythemia vera-associated Jak2 V617F mutant induces tumorigenesis in nude mice2009
- Author(s)
  Abe M, Funakoshi-Tago M, Tago K, Kasahara T., 他3名
- Journal Title
  
  Int Immunopharmacol. 9(7-8)
  
  Pages: 870-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] Dermatophagoides farinaeextract induces severe atopic dermatitis in NC/Nga mice, which is effectively suppressed by the administration of tacrolimus ointment2009
- Author(s)
  Oshio T, Sasaki Y, Funakoshi-Tago M, Yokota E, Sonoda Y, Matsuoka H, Kasahara T.
- Journal Title
  
  Int Immunopharmacol 9(4)
  
  Pages: 403-11
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] The polycythemia vera-associated Jak2 V617F mutant induces tumorigenesis in nude mice2009
- Author(s)
  Abe M, Funakoshi-Tago M, Tago K, Kamishimoto J, Aizu-Yokota E, Sonoda Y, Kasahara T
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 9(7-8) Pages: 870-877
- Data Source
  KAKENHI-PROJECT-21590072
[Journal Article] The acute lymphoblastic leukemia-associated Jak2 L611S mutant induces tumorigenesis in nude mice2009
- Author(s)
  Funakoshi-Tago M, Tago K, Sumi K, Abe M, Aizu-Yokota E, Oshio T, Sonoda Y, Kasahara T.
- Journal Title
  
  J Biol Chem. 284(19)
  
  Pages: 12680-90
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-kappaB p65 phosphorylation at serine 2762009
- Author(s)
  Furusawa JI, Funakoshi-Tago M, Tago K, Mashino T, Inoue H, Sonoda Y, Kasahara T.
- Journal Title
  
  Cell Signaling 21(5)
  
  Pages: 778-85
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] TRAF6 is a critical signal transducer in IL-33 signaling pathway.2008
- Author(s)
  Funakoshi-Tago M, Tago K, Kasahara T, et al.
- Journal Title
  
  Cell Signaling 20(9)
  
  Pages: 1679-1686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Celecoxib potently inhibits TNFa-induced nuclear translocationand activation of NF-kB.2008
- Author(s)
  Funakoshi-Tago M, Shimizu T, Kasahara, T, et. al.
- Journal Title
  
  Biochemical Pharmacol. 76(5)
  
  Pages: 662-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis.2008
- Author(s)
  Kaneda T, Sonoda Y, Ando K, Suzuki T, Sasaki Y, Oshio T, Tago M, Kasahara T
- Journal Title
  
  Cancer Lett. Vol.270
  
  Pages: 354-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] TRAF6 is a critical signal transducer in IL-33 signaling pathway2008
- Author(s)
  Funakoshi-Tago M, Tago K, Hayakawa M, Tominaga S-I, Ohshio T, Sonoda Y, Kasahara T.
- Journal Title
  
  Cell Signaling 20(9)
  
  Pages: 1679-86
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] A synthetic glycosphingolipid-induced antiproliferative effect in melanoma cells is associated with suppression of FAK, Akt, and Erk activation.2008
- Author(s)
  Sonoda Y, Hada N, Kaneda T, Suzuki T, Ohshio T, Takeda T, Kasahara T.
- Journal Title
  
  Biol Pharm Bull. Vol.31
  
  Pages: 1279-83
- NAID
  110006684355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] A synthetic glycosphingolipid-induced antiproliferative effect in melanoma cells is associated with suppression ofFAK, Akt, and Erk activation.2008
- Author(s)
  Sonoda Y, Hada N, Kaneda T, Suzuki T, Ohshio T, Takeda T, Kasahara T.
- Journal Title
  
  Biol Pharm Bull. 31
  
  Pages: 1279-1283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] Parganas E, Ihle JN. Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway2008
- Author(s)
  Funakoshi-Tago M, Tago K, Kasahara T,
- Journal Title
  
  Cell Signaling 20(11)
  
  Pages: 1995-2001
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis.2008
- Author(s)
  Kaneda T, Sonoda Y, Ando K, Suzuki T, Sasaki Y, Oshio T, Funakoshi-Tago M, Kasahara T.
- Journal Title
  
  Cancer Lett. 270(2)
  
  Pages: 354-61
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Mutation ofY925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis.2008
- Author(s)
  Kaneda T, Sonoda Y, AndoK, Suzuki T, Sasaki Y, Oshio T, Tago M, Kasahara T.
- Journal Title
  
  Cancer Lett. 270
  
  Pages: 354-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590069
[Journal Article] Celecoxib potently inhibits TNFa-induced nuclear translocation and activation of NF-Kb2008
- Author(s)
  Funakoshi-Tago M, Shimizu T, Tago K, Nakamura M, Itoh H, Sonoda Y, Kasahara T.
- Journal Title
  
  Biochemical Pharmacol 76(5)
  
  Pages: 662-71
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis.2008
- Author(s)
  Kaneda T, Sonoda Y, Ando K, Kasahara T., et al.
- Journal Title
  
  Cancer Lett. 270(2)
  
  Pages: 354-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] A synthetic glycosphingolipid-induced antiproliferative effect in melanoma cells is associated with suppression of FAK, Akt, and Erk activation2008
- Author(s)
  Sonoda Y, Hada N, Kaneda T, Suzuki T, Ohshio T, Takeda T, Kasahara T.
- Journal Title
  
  Biol Pharm Bull 31(6)
  
  Pages: 1279-83
- NAID
  110006684355
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Cofilin plays a critical role in IL-8-dependent chemotaxis of neutrophilic HL-60 cells through changes in phosphorylation.2007
- Author(s)
  Hirayama A, Adachi R, Otani S, Kasahara T, Suzuki K
- Journal Title
  
  J Leukoc Biol 81(3)
  
  Pages: 720-728
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Suppression of Endoplasmic Reticulum Stress-induced Caspase Activation and Cell Death by the Overexpression of Bcl-xL or Bcl-2.2007
- Author(s)
  Murakami Y, Aizu-Yokota E, Sonoda Y, Ohta S, Kasahara T.
- Journal Title
  
  Journal of Biochemistry (Tokyo) 141(3)
  
  Pages: 401-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Cofilin plays a critical role in IL-8-dependent chemotaxis of neutroohilic HL-60 cells through changes in phosphorylation.2007
- Author(s)
  Hirayama A, Adachi R, Otani S, Kasahara T, Suzuki K.
- Journal Title
  
  Journal of Leukocyte Biology 81(3)
  
  Pages: 720-728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Production and regulation of eotaxin-2/CCL24 in a differentiated human leukemic cell line, HT93.2007
- Author(s)
  Yoshida N, Aizu-Yokota E, Sonoda Y, Moriwaki Y, Kishi K, Kasahara T.
- Journal Title
  
  Biol Pharm Bull. 30(10)
  
  Pages: 1826-32
- NAID
  110006436358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Focal adhesion kinase determines the fate of death or survival of cells in response to TNFα in the presence of actinomycin D.2007
- Author(s)
  Takahashi R, Sonoda Y, Ichikawa D, Yoshida N, Aizu-Yokota E, Kasahara T
- Journal Title
  
  Biochem Biophys Acta 1770
  
  Pages: 518-526
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Suppression of Endoplasmic Reticulum Stress-induced Caspase Activation and Cell Death by the Overexpression of Bcl-xL or Bcl-2.2007
- Author(s)
  Murakami Y, Aizu-Yokota E, Sonoda Y, Ohta S, Kasahara T
- Journal Title
  
  J Biochem (Tokyo) 141(Epub ahead of print)
  
  Pages: 401-410
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Focal adhesion kinase determines the fate of death or survival of cells in response to TNFa in the presence of actinomycin D.2007
- Author(s)
  Takahashi R, Sonoda Y, Ichikawa D, Yoshida N, Aizu-Yokota E, Kasahara T
- Journal Title
  
  Biochem Biophys Acta 1770(4)
  
  Pages: 518-526
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Focal adhesion kinase determines the fate of death or survival of cells in response to TNFa in the presence of actinomycin D.2007
- Author(s)
  Takahashi R, Sonoda Y, Ichikawa D, Yoshida N, Aizu-Yokota E, Kasahara T.
- Journal Title
  
  Biochem Biophys Acta 1770
  
  Pages: 518-526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590075
[Journal Article] Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.2007
- Author(s)
  Murakami Y, Aizu-Yokota E, Sopnoda Y, Ohta S, Kasahara T
- Journal Title
  
  J Biochem (Tokyo) 141
  
  Pages: 401-410
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] MEK-ERK is involved in SUMO-1 foci formation on apoptosis.2007
- Author(s)
  R.Utsubo-Kuniyoshi, Y.Terui, Y.Sonoda, T.Kasahara, K.Hatake他5名
- Journal Title
  
  Cancer Sci, 2007 Jan 31; (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] MEK-ERK is involved in SUMO-1 foci formation on apoptosis.2007
- Author(s)
  R.Utsubo-Kuniyoshi, Y.Terui, Y.Mishima, A.Rokudai, Y.Mishima, N.Sugimura, K.Kojima, Y.Sonoda, T.Kasahara, K.Hatake
- Journal Title
  
  Cancer Sci (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] MEK-ERK is involved in SUMO-1 foci formation on apoptosis.2007
- Author(s)
  R.Utsubo-Kuniyoshi, Y.Terui, Y.Sonoda, T.Kasahara, 他5名
- Journal Title
  
  Cancer Sci 2007 Jan 31; [Epub ahead of print]
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.2007
- Author(s)
  Murakami Y, Aizu-Yokota E, Sonoda Y, Ohta S, Kasahara T
- Journal Title
  
  J Biochem (Tokyo) 141
  
  Pages: 401-410
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Cofilin plays a critical role in IL-8-dependent chemotaxis of neutrophilic HL-60 cells through changes in phosphorylation.2007
- Author(s)
  Hirayama A, Adachi R, Otani S, Kasahara T, Suzuki K
- Journal Title
  
  J Leukoc Biol. 81(3)
  
  Pages: 720-728
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Differential regulation of eotaxin-1/CCL11 and eotaxin-3/CCL26 production by the TNF-a and IL-4 stimulated human lung fibroblast2006
- Author(s)
  Rokudai R, Aizu-Yokota E, Sonoda Y, Kasahara T, Hatake K.他4名
- Journal Title
  
  Biol Pharm Bull 29(6)
  
  Pages: 1102-1109
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Glycyrrhizin derivative inhibits eotaxin 1 production via STAT6 in human lung fibroblasts2006
- Author(s)
  Matsui S, Sonoda Y, Sekiya S, Aizu-YokotA E, Kasahara T
- Journal Title
  
  Int Immunopharmacol. 6
  
  Pages: 369-375
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Glycyrrhizin derivative inhibits eotaxin 1 production via STAT6 in human lung fibroblasts2006
- Author(s)
  Matsui S, Sonoda Y, Sekiya S, Aizu-Yokot A E, Kasahara T
- Journal Title
  
  Int Immunopharmacol. 6
  
  Pages: 369-375
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] C/EBPa inactivation in FAK-overexpressed cells causes impaired differentiation2006
- Author(s)
  Hashimoto K, Sonoda Y, Yamakado M, Funakoshi-Tago M, Yoshida Y, Rokudai A, Aizu-Yokota E, Kasahara T
- Journal Title
  
  Cell Signaling 18
  
  Pages: 955-963
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Glycyrrhizin derivative inhibits eotaxin 1 production via STAT6 in human lung fibroblasts2006
- Author(s)
  Matsui S, Sonoda Y, Sekiya S, Aizu-Yokota E, Kasahara T
- Journal Title
  
  Int Immunopharmacol 6
  
  Pages: 369-375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Differential regulation of eotaxin-1/CCL11 and eotaxin-3 /CCL26 production by the TNF-a and IL-4 stimulated human lung fibroblast2006
- Author(s)
  Rokudai R, Aizu-Yokota E, Sonoda Y, Kasahara T, Hatake K 他4名
- Journal Title
  
  Biol Pharm Bull 29(6)
  
  Pages: 1102-1109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] TNF-receptor associated factor 6-deficient fibroblast is sensitive to the TNF-a-induced cell death : Involvement of reactive oxygen species.2006
- Author(s)
  Ichikawa D, Funakoshi-Tago M, Aizu-Yokota E, Sonoda Y, Inoue J-I, Kasahara T
- Journal Title
  
  Biochem Biophys Res Commun 351
  
  Pages: 93-98
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Differential Regulation of Eotaxin-1/CCL11 and Eotaxin-3/CCL26 Production by the TNF-□ and IL-4 stimulated Human Lung Fibroblast2006
- Author(s)
  Rokudai R, Terui Y, Kuniyoshi R, Mishima Y, Mishima Y, Aizu-Yokota E, Sonoda Y, Kasahara T, Hatake K
- Journal Title
  
  Biol Pharm Bull 29(6)
  
  Pages: 1102-1109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] TNF-receptor associated factor 6-deficient fibroblast is sensitive to the TNF-α-induced cell death : Involvement of reactive oxygen species.2006
- Author(s)
  Ichikawa D, Funakoshi-Tago M, Aizu-Yokota E, Sonoda Y, Inoue J-I, Kasahara T
- Journal Title
  
  Biochem Biophys Res Commun 351
  
  Pages: 93-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] C/EBPa inactivation in FAK-overexpressed cells causes impaired differentiation2006
- Author(s)
  Hashimoto K, Sonoda Y, Aizu-Yokota E, Kasahara T
- Journal Title
  
  Cell Signalling 18
  
  Pages: 955-963
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Indirubin, a Chinese antileukemia drug, enhances the neutrophilic differentiation of human promyelocyte HL-60 cells.2005
- Author(s)
  Suzuki K, Adachi R, Hirayama A, Watanabe H, Otani S, Watanabe Y, Kasahara T
- Journal Title
  
  Brit J Haematol. 130
  
  Pages: 681-690
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Improved gene expression in resting macrophages using an oligopeptide derived from Vpr of human immunodeficiency virus type-1.2005
- Author(s)
  Mizoguchi I, Ooe Y, Hoshin S, Kasahara T, ほか7名
- Journal Title
  
  Biochem Biophys Res Commun 338
  
  Pages: 1499-1506
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Functional role of c-Src in IL-1-induced NF-kB activation : c-Src is one of the components of IKK complex.2005
- Author(s)
  Funakoshi-Tago, M., Tago K., Andoh K., Sonoda Y., Tominaga S-I., Kasahara T.
- Journal Title
  
  J. Biochem (Tokyo) 137
  
  Pages: 189-197
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Indirubin, a Chinese antileukemia drug, enhances the neutrophilic differentiation of human promyelocyte HL-60 cells.2005
- Author(s)
  Suzuki K, Adachi R, Hirayama A, Watanabe H, Otani S, Watanabe Y, Kasahara T
- Journal Title
  
  Brit J Haematol 130
  
  Pages: 681-690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Indirubin, a Chinese antileukemia drug, enhances the neutrophilic differentiation of human promyelocyte HL-60 celIs.2005
- Author(s)
  Suzuki K, Adachi R, Otani S, Watanabe Y, Kasahara T, ほか2名
- Journal Title
  
  British J Haematol. 130
  
  Pages: 681-690
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Improved Gene Expression in Resting Macrophages using an Oligopeptide Derived from Vpr of Human Immunodeficiency Virus Type-1.2005
- Author(s)
  Mizoguchi I, Ooe Y, Hoshin S, Shimura M, Kasahara T, Ohta T, Shigeyuki Kano S, Takaku F, Nakayama Y, Ishizaka Y
- Journal Title
  
  Biochem.Biophys.Res.Commun 338
  
  Pages: 1499-1506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Functional role of c-Src in IL-1-induced NF-kB activation : c-Src is one of the components of IKK complex.2005
- Author(s)
  Funakoshi-Tago M, Tago K, Ando K, Sonoda Y, Kasahara T.
- Journal Title
  
  J Biochem. 137
  
  Pages: 189-197
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Functional role of c-Src in IL-1-induced NF-kB activation : c-Src is one of the components of IKK complex.2005
- Author(s)
  Funakoshi-Tago, M., Tago K., Andoh K., Sonoda Y., Tominaga S-I., Kasahara T
- Journal Title
  
  J. Biochem 137
  
  Pages: 189-197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Improved Gene Expression in Resting Macrophages using an Oligopeptide Derived from Vpr of Human Immunodeficiency Virus Type-1.2005
- Author(s)
  Mizoguchi I, Ooe Y, Hoshin S, Shimura M, Kasahara T, 他4名
- Journal Title
  
  Biochem Biophys Res Commun 338
  
  Pages: 1499-1506
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Down-regulation of procaspase-8 expression by FAK protects HL-60 cells from TRAIL-induced apoptosis.2004
- Author(s)
  Tamagiku Y, Sonoda Y, Kasahara Tほか
- Journal Title
  
  Biochem Biophys Res Commun. 323(2)
  
  Pages: 445-452
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Glycyrrhizin and related compounds downregulate production of inflammatory chemokines IL-8 and eotaxin 1 in a human lung fibroblast cell line2004
- Author(s)
  Matsui S, Matsumoto H, Sonoda Y, Aizu-Yokota E, Sato S, Kasahara T
- Journal Title
  
  Int Immunopharmcol 4
  
  Pages: 1633-1644
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Effect of various catechins on the IL-12p40 production by murine peritoneal macrophages and a macrophage cell line, J774.12004
- Author(s)
  Ichikawa D, Sonoda S, Kasahara T ほか
- Journal Title
  
  Biol Pharmcol Bull 27(9)
  
  Pages: 1353-1358
- NAID
  110003608975
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Elevated interleukin-8 in cervical mucus as an indicator for treatment to prevent premature birth and preterm, pre-labor2004
- Author(s)
  Sakai M, Kasahara T, ほか
- Journal Title
  
  Am J Reprod Immunol. 51(3)
  
  Pages: 220-225
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Proteome analysis of focal adhesion kinase(FAK) - overexpressing cells2004
- Author(s)
  Utsubo R, Sonoda Y, Kasahara T ほか
- Journal Title
  
  Biol Pharmcol Bull 27(11)
  
  Pages: 1735-1741
- NAID
  110003608689
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Induction of antioxidant enzymes by FAK in a human leukemic cell line, HL-60.2004
- Author(s)
  Sonoda Y, Aiba N, Utsubo R, Koguchi E, Kasahara T
- Journal Title
  
  Biochim Biophys Acta 1683(1-3)
  
  Pages: 22-32
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Down-regulation of procaspase-8 expression by FAK protects HL-60 cells from TRAIL-induced apoptosis.2004
- Author(s)
  Tamagiku Y, Sonoda Y, Kunisawa M, Ichikawa D, Aizu-Yokota E, Kasahara T
- Journal Title
  
  Biochem Biophys Res Commun 323(2)
  
  Pages: 445-452
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Proteome analysis of focal adhesion kinase (FAK)-overexpressing cells2004
- Author(s)
  Utsubo R, Sonoda Y, Aizu-Yokota E, Kasahara T 他21名
- Journal Title
  
  Biol Pharm Bull 27(11)
  
  Pages: 1735-1741
- NAID
  110003608689
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Glycyrrhizin and related compounds downregulate production of inflammatory chemokines IL-8 and eotaxin 1 in a human lung.2004
- Author(s)
  Matsui S, Sonoda Y, Kasahara T ほか
- Journal Title
  
  Int Immunopharmcol 4
  
  Pages: 1633-1644
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Effect of various catechins on the IL-12p40 production by murine peritoneal macrophages and a macrophage cell line, J774.12004
- Author(s)
  Ichikawa D, Matsui A, Imai M, Sonoda S, Kasahara T
- Journal Title
  
  Biol Pharmcol Bull 27(9)
  
  Pages: 1353-1358
- NAID
  110003608975
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Proteome analysis of focal adhesion kinase (FAK)-overexpressing cells2004
- Author(s)
  Utsubo R, Sonoda Y, Takahashi R, Iijima, I Aizu-Yokota E, Kasahara T
- Journal Title
  
  Biol Pharm Bull 27 (11)
  
  Pages: 1735-1741
- NAID
  110003608689
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Down-regulation of procaspase-8 expression by focal adhesion kinase (FAK) protects HL-60 cells from TRAIL-induced apoptosis.2004
- Author(s)
  Tamagiku Y, Sonoda Y, Kunisawa M, Ichikawa D, Aizu-Yokota E, Kasahara T
- Journal Title
  
  Biochem Biophys Res Commun 323(2)
  
  Pages: 445-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Glycyrrhizin and related compounds downregulate production of inflammatory chemokines IL-8 and eotaxin 1 in a human lung fibroblast cell line2004
- Author(s)
  Matsui S, Sonoda Y, Aizu-Yokota E, Sato S, Kasahara T: 他1名
- Journal Title
  
  Int Immunopharmcol 4
  
  Pages: 1633-1644
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Effect of various catechins on the IL-12p40 production by murin peritoneal macrophages and a macrophaee cell line, J774.12004
- Author(s)
  Ichikawa D, Matsui A, Imai M, Sonoda S, Kasahara T
- Journal Title
  
  Biol Pharmcol Bull 27(9)
  
  Pages: 1353-1358
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Induction of antioxidant enzymes by FAK in a human leukemic cell line, HL-60.2004
- Author(s)
  Sonoda Y, Aiba N, Utsubo R, Koguchi E, Hasegawa M, Kasahara T
- Journal Title
  
  Biochim Biophys Acta 1683 (1-3
  
  Pages: 22-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] Induction of antioxidant enzymes by FAK in a human leukemic cell line HL-602004
- Author(s)
  Sonoda Y, Kasahara T, ほか
- Journal Title
  
  Biochim Biophys Acta 1683(1-3)
  
  Pages: 22-32
- Data Source
  KAKENHI-PROJECT-16390024
[Journal Article] FTY720, a novel immunosuppressive agent, induces apopotosis in human glioma cells2001
- Author(s)
  Sonoda Y, Yamamoto D, Kasahara T, et al.
- Journal Title
  
  Biochem. Biophys. Res.Commun. 281,2
  
  Pages: 282-288
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11672275
[Journal Article] Differential involvement of p38 mitogen-activated protein kinase and phosphatidyl inositol 3-kinase in the IL-1 mediated NF-kB and AP-1 activation2001
- Author(s)
  Funakoshi M, Sonoda Y, Tago K, Tominaga S, Kasahara T.
- Journal Title
  
  Int J Immunopharmacol. 1,3
  
  Pages: 595-604
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11672275
[Journal Article] Anti-apoptotic role of focal adhesion kinase(FAK)2000
- Author(s)
  Sonoda Y, Matsumoto Y, Funakoshi M, Yamamoto D, Hanks SK, Kasahara T
- Journal Title
  
  J Biol Chem 275(21)
  
  Pages: 16309-16315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11672275
[Journal Article] Anti-apoptotic role of focal adhesion kinase(FAK)2000
- Author(s)
  Sonoda Y, Matsumoto Y, Funakoshi M, Yamamoto D, Hanks SK, Kasahara T
- Journal Title
  
  J Biol Chem 275,21
  
  Pages: 16309-16315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11672275
[Journal Article] Differential induction of JE/MCP-1 in subclones from a murine macrophage cell line, RAW264.7 ; Role of kB-3 binding protein2000
- Author(s)
  Ueno M, Sonoda Y, Funakoshi M, Mukaida N, Nose K, Kasahara T.
- Journal Title
  
  Cytokine 12,3
  
  Pages: 207-219
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11672275
[Journal Article] FAK is the upstream signal protein of the PI3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line1999
- Author(s)
  Sonoda Y, Watanabe S, Matsumoto Y, Aizu-Yokota E, Kasahara T
- Journal Title
  
  J Biol Chem 274,15
  
  Pages: 10566-10570
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11672275
[Journal Article] FAK is the upstream signal protein of the PI3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line1999
- Author(s)
  Sonoda Y, Watanabe S, Matsumoto Y, Aizu-Yokota E, Kasahara T.
- Journal Title
  
  J Biol Chem 274(15)
  
  Pages: 10566-10570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11672275
[Journal Article] FTY720, a novel immunosuppressive agent, induces apopotosis in human glioma cells
- Author(s)
  Sonoda Y, Yamamoto D, Sakurai S, Hasegawa M, Aizu-Yokota E, Momoi T, Kasahara T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 281(2)
  
  Pages: 282-288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11672275
[Patent] 皮膚炎治療剤及び皮膚掻痒治療剤2011
- Inventor(s)
  笠原忠、大塩智之, 井上秀雄
- Industrial Property Rights Holder
  株式会社ミノファーゲン製薬、学校法人慶應義塾
- Filing Date
  2011-08-05
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 絶食によるマウス各臓器の適応応答とリモデリング2014
- Author(s)
  山本隼也, 鎌田祥太郎, 笠原忠, 石井功
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都市
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] 各必須アミノ酸欠失餌により異なるマウスの全身性適応応答2014
- Author(s)
  鎌田祥太郎, 山本隼也, 上條健太, 落合崇人, 森田珠子, 吉冨友里香, 萩谷至史, 久保田将史, 大久保里佳, 笠原忠, 石井功
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都市
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] アセトアミノフェン肝障害に対するトランススルフレーション酵素の保護的役割2014
- Author(s)
  石井功, 萩谷至史, 鎌田祥太郎, 光岡紗野, 吉田早織, 山本隼也, 大久保里佳, 笠原忠
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都市
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] プロポリス含有フラボノイドのIL-33シグナル伝達経路に及ぼす影響.2013
- Author(s)
  岡本一飛, 宮川友理香, 出海里佳, 成川佑次, 木内文之, 多胡めぐみ, 笠原忠.
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] A fullerene derivative inhibits IL-33-induced inflammatory cytokines via IKKβ-specific pathway.2013
- Author(s)
  Kasahara T, Miyagawa Y, Okamoto K, Mashino T, Funakoshi-Tago M.
- Organizer
  Cytokine 2013
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] IL-33のシグナル伝達経路におけるにビスマロン酸型フラーレン誘導体の影響.2013
- Author(s)
  宮川友理香, 多胡めぐみ, 増野匡彦, 笠原忠.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] V617FJAK2変異体による細胞増殖におけるCIS/SOCSファミリーの役割.2013
- Author(s)
  上田史仁, 森脇拓郎, 多胡めぐみ, 笠原忠.
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] 慢性骨髄増殖性腫瘍の原因遺伝子V617FJAK2変異体による細胞増殖誘導におけるEpoRリン酸化の役割.2013
- Author(s)
  上田史仁, 根本望, 多胡めぐみ, 笠原忠.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] JAK2 V617F mutation causes cytokine-independent growth and tumorigenesis -roles of stat5 and c-myc2012
- Author(s)
  T. Kasahara , M. Funakoshi-Tago, K. Tago
- Organizer
  Cytokines 2012 -Joint meeting of 10th ICS and ISICR
- Place of Presentation
  Geneva
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] ヒスタミンのヒト好酸球機能への影響の解析2012
- Author(s)
  保科直美, 平林あゆみ, 園田よし子, 笠原忠
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌市
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] JAK2新規リン酸化部位Y423の同定および機能解析2011
- Author(s)
  村上はるか、上四元純、多胡めぐみ、笠原忠
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都市
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 慢性骨髄増殖性腫瘍由来JAK2変異体のシグナル伝達におけるCISの機能解析2011
- Author(s)
  森脇拓郎、岡本一飛、多胡めぐみ、笠原忠
- Organizer
  第10回次世代を担う若手ファーマ・バイオフォーラム2011
- Place of Presentation
  仙台市
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 慢性骨髄増殖性腫瘍由来JAK2変異体による抗がん剤耐性におけるFANCCの役割2011
- Author(s)
  上田史仁、鷲見和也、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第55回薬学会関東支部会
- Place of Presentation
  千葉市
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 慢性骨髄増殖性腫瘍由来JAK2変異体のシグナル伝達経路におけるc-Mycの役割2011
- Author(s)
  庄司貴一、鷲見和也、多胡めぐみ、笠原忠
- Organizer
  第12回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  富山市
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] フラーレン誘導体を用いた慢性骨髄増殖性腫瘍の治療法の開発2011
- Author(s)
  田中和之、長田達明、多胡めぐみ、中村成夫、増野匡彦、笠原忠
- Organizer
  第12回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  富山市
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] JAK2変異体のシグナル伝達におけるPim1の役割の解析2011
- Author(s)
  田中和之、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都市
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 真性赤血球増加症におけるセリン・プロテアーゼインヒビター群の役割2010
- Author(s)
  長田達明、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第11回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 真性赤血球増加症由来JAK2変異体(V617F)のシグナル伝達経路に及ぼすSTAT5の役割2010
- Author(s)
  多胡めぐみ、阿部美雪、園田よし子、笠原忠
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] JAK2変異体のシグナル伝達におけるPimの役割の解析2010
- Author(s)
  田中和之、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第83回日本生化学大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 真性赤血球増加症由来JAK2変異体(V617F)のシグナル伝達経路に及ぼすSTAT5の役割2010
- Author(s)
  多胡めぐみ, 阿部美雪, 園田よし子, 笠原忠
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 真性赤血球増加症由来JAK2変異体のシグナル伝達におけるc-Mycの役割2010
- Author(s)
  鷲見和也、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第54回薬学会関東支部会
- Place of Presentation
  東京
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] FAK及びPLP2ノックダウンによるメラノーマ増殖抑制について2010
- Author(s)
  小澤広規、保科直美、多胡めぐみ、園田よし子, 笠原忠
- Organizer
  第83回日本生化学大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 甘草由来 Licochalcone AのTNFα誘導性NF-κBの活性化に及ぼす影響2010
- Author(s)
  鶴谷理奈, 中村慶, 多胡めぐみ, 畑中雅史, 増野匡彦, 笠原忠
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] FAK及びPLP2ノックダウンによるメラノーマ転移抑制について2010
- Author(s)
  小澤広規, 園田よし子, 多胡めぐみ, 笠原忠
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] FAK及びPLP2ノックダウンによるメラノーマ転移抑制について2010
- Author(s)
  小澤広規、園田よし子、多胡めぐみ、笠原忠
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] FAK及びPLP2ノックダウンによるメラノーマ増殖抑制について2010
- Author(s)
  小澤広規、保科直美、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第83回日本生化学大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] JAK2変異体のシグナル伝達におけるPimの役割の解析2010
- Author(s)
  田中和之、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第83回日本生化学大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] TNFαシグナル伝達に及ぼす Flavonoid 化合物の影響2010
- Author(s)
  中村慶, 多胡めぐみ, 園田よし子, 笠原忠
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 真性赤血球増加症由来JAK2 変異体のシグナル伝達におけるc-Mycの役割2010
- Author(s)
  鷲見和也、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第54回薬学会関東支部会
- Place of Presentation
  東京
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] FAK及びPLP2ノックダウンによるメラノーマ転移抑制について2010
- Author(s)
  小澤広規, 園田よし子, 保科直美, 田中和之, 多胡めぐみ, 笠原忠
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20590069
[Presentation] JAK2変異体(V617F)のシグナル伝達経路に及ぼすSOCS3の役割の解析2010
- Author(s)
  鶴谷理奈、森脇拓郎、多胡めぐみ、笠原忠
- Organizer
  第83回日本生化学大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] JAK2変異体(V617F)によるアポトーシス耐性ならびに腫瘍形成能の解析2010
- Author(s)
  上四元純, 多胡めぐみ, 園田よし子, 笠原忠
- Organizer
  第11回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] FAK及びPLP2ノックダウンによるメラノーマ転移抑制について2010
- Author(s)
  小澤広規、園田よし子、保科直美、田中和之、多胡めぐみ、笠原忠
- Organizer
  第33回分子生物学会年会、第83回生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20590069
[Presentation] ドキソルビシンおよびグルタチオン修飾ドキソルビシンのアポトーシス誘導機序の解析.2009
- Author(s)
  鈴木降晴, 園田よし子, 多胡めぐみ, 笠原忠, 朝倉正, 大川清.
- Organizer
  日本薬学会1 2 8年会
- Place of Presentation
  京都市
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] 4P-219 真性赤血球増加症由来JAK2 変異体(V617F)によるファンコニ貧血原因遺伝子群の発現誘導2009
- Author(s)
  鷲見和也, 多胡めぐみ, 園田よし子, 笠原忠
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 4P-220 真性赤血球増加症患者由来JAK2 変異体(V617F)のシグナル伝達経路に及ぼすStat5 の役割2009
- Author(s)
  長田達明, 多胡めぐみ, 園田よし子, 笠原忠
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] プロテオリピドプロテインのメラノーマ転移誘導の解析(講演要旨集)2009
- Author(s)
  割田雅子, 多胡めぐみ, 園田よし子, 笠原忠
- Organizer
  日本薬学会129年会
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] 真性赤血球増加症由来JAK2変異体(V617F)によるファンコニ貧血原因遺伝子群の発現誘導2009
- Author(s)
  鷲見和也、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸市
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] プロテオリピドプロテインのメラノーマ転移誘導の解析.2009
- Author(s)
  割田雅子, 多胡めぐみ, 園田よし子, 笠原忠.
- Organizer
  日本薬学会第128年会
- Place of Presentation
  京都市
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] 真性赤血球増加症由来JAK2点変異(V617F)によるアポトーシス耐性機構の解析2009
- Author(s)
  上四元純、多胡めぐみ、園田よし子、笠原忠
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸市
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] 4P-221 真性赤血球増加症由来JAK2 点変異(V617F)によるアポトーシス耐性機構の解析2009
- Author(s)
  上四元純, 多胡めぐみ, 園田よし子, 笠原忠
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21590072
[Presentation] LicochalconeD によるマスト細胞脱顆粒反応抑制機序の解析2008
- Author(s)
  谷藤章太, 吉田直美, 多胡めぐみ, 横田恵理子, 園田よし子, 岩田進, 笠原忠
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市(講演要旨集-)(10)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] TNFα誘導性NF-k B の活性化に及ぼすLicochalconeAの影響.2008
- Author(s)
  田辺紗詠子, 多胡めぐみ, 笠原忠, ほか.
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] 接着斑キナーゼ(FAK)のメラノーマ転移における役割解析2008
- Author(s)
  笠原忠, 園田よし子
- Organizer
  52回日本薬学会関東支部大会
- Place of Presentation
  東京理科大学
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-20590069
[Presentation] 接着斑キナーゼ(FAK)のメラノーマ転移における役割解析2008
- Author(s)
  笠原忠
- Organizer
  第52回日本薬学会関東支部会
- Place of Presentation
  東京理科大学
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-20590069
[Presentation] TNF-αシグナル伝達におけるcelecoxib の作用について2008
- Author(s)
  清水妙子, 多胡めぐみ, 園田よし子, 中村元洋, 多胡憲治, 伊東広, 笠原忠
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市(講演要旨集-3)(81)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] 破骨細胞における中間径フィラメントの役割について2008
- Author(s)
  安達玲子、櫻井智子、笠原忠、鈴木和博、手島玲子
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市(講演要旨集-3)(96)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] TNF シグナル系におけるTNFReceptor Associated Factor 6 の役割2008
- Author(s)
  鎌田智之, 橋口雄輔, 市川大樹, 多胡めぐみ, 横田恵理子, 園田よし子, 井上純一郎, 笠原忠
- Organizer
  日本薬学会第128 年会
- Place of Presentation
  横浜市(講演要旨集-3)(87)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] 真性赤血球増加症由来JAK2 の点変異(V617F)による抗アポトーシス作用の解析2007
- Author(s)
  阿部美雪, 多胡めぐみ, 園田よし子, 笠原忠
- Organizer
  第80 回日本生化学会大会
- Place of Presentation
  横浜市(講演要旨集)(1P-0572)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] 甘草由来LicochalconeA 及びその誘導体の一酸化窒素(NO)酸性経路に及ぼす影響2007
- Author(s)
  古澤純一, 多胡めぐみ, 谷藤章太, 谷香世子, 岩田進, 笠原忠
- Organizer
  第80 回日本生化学会大会
- Place of Presentation
  横浜市(講演要旨集)(4P-0468)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] Anti-apoptotic effect of activated JAK2 with the V617F point mutation2007
- Author(s)
  阿部美雪, 多胡めぐみ, 園田よし子, 笠原忠
- Organizer
  第80 回日本生化学会
- Place of Presentation
  横浜市(1P-0572)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] TNFシグナル系におけるTRAF6の役割2007
- Author(s)
  鎌田智之、橋口拓植、市川大樹、多胡めぐみ、横田恵理子, 園田よし子, 笠原忠
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2007-03-27
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] 甘草Licochalcone Aおよびその誘導体の一酸化窒素(NO)産生経路に及ぼす影響2007
- Author(s)
  古澤純一、多胡めぐみ、谷藤章太、谷香世子、岩田進, 笠原忠
- Organizer
  第80回日本生化学大会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] IL-33シグナル伝達経路におけるTRAF6の役割2007
- Author(s)
  多胡めぐみ、多胡憲治、早川盛貞、富永真一、園田よし子, 笠原忠
- Organizer
  第80回日本生化学大会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] IL-33 シグナル伝達経路におけるTRAF6 の役割の解析2007
- Author(s)
  多胡めぐみ, 多胡憲治, 早川盛貞, 富永眞一, 園田よし子, 笠原忠
- Organizer
  第80 回日本生化学会大会
- Place of Presentation
  横浜市(講演要旨集)(2P-0229)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] Production and regulaton of eotaxin-2/CCL24 in a differentiated human leukemic cell line, HT932007
- Author(s)
  Yoshida N, Sonoda Y, Kasahara T.
- Organizer
  第16回日本免疫学会総会
- Place of Presentation
  東京都(講演要旨集)(187)
- Data Source
  KAKENHI-PROJECT-19590075
[Presentation] JAK2変異体による生存シグナルにおけるHMGA1bの役割
- Author(s)
  高橋里実、宮川友理香、多胡めぐみ、杉山直幸、笠原忠
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] JAK2変異体の増殖シグナルにおけるSOCS3の抑制機構の解析
- Author(s)
  石原亜季、鶴谷理奈、多胡めぐみ、笠原忠
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] IL-33のシグナル伝達に及ぼすビスマロン酸フラーレン誘導体の影響
- Author(s)
  宮川友理香，横田重信、岡本一飛、多胡めぐみ、増野　匡彦、笠原　忠
- Organizer
  １３３年回日本薬学会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] Critical roles of Myc-ODC axis in the cellular transformation induced by myeloproliferative neoplasm-associated JAK2 V617F mutant
- Author(s)
  多胡めぐみ、鷲見和也、多胡憲治、笠原忠
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24590091
[Presentation] ParvifloroneによるTNFα誘導性NF-kBの活性化の抑制機構
- Author(s)
  野村さやか、多胡めぐみ、成川佑次、笠原　忠
- Organizer
  １３３年回日本薬学会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24590091

1. SONODA Yoshiko (30050743)

# of Collaborated Projects: 8 results

# of Collaborated Products: 59 results
2. MUKAIDA Naofumi (30182067)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. TAGO Megumi (30445192)

# of Collaborated Projects: 5 results

# of Collaborated Products: 119 results
4. YOKOTA Eriko (10222457)

# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
5. YAMAGUCHI Yuji (00220286)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. OPPENHEIM Joost.J.

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. ONOZAKI Kikuo (20101313)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MATSUSHIMA Kouji (50222427)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. LARSEN Chris

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YAGISAWA Hitoshi (40192380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MURAKAMI Seishi (90019878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HARADA Akihisa (00228636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOBAYASHI Yoshiro (10134610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SUZUKI Kazuhiro (10154527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ADACHI Reiko (10291113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. AKIYAMA Mariko (60019867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KAWAI Tadahi (60048957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ITOH Yoshihisa (20129026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 須田年生 (60118453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 高余洲 (30234686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 松島網治

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. CHRISTIAN G.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ETTORE APPEL

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. JOOST J. OPP

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. OPPENHEIM Joost J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. LARSEN Christian

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. APPELLA Ettore

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. APPELLA Etto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. THESTRUPーPED クリスチ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. PEDERSEN Kri

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. JOOST J. Oppenheim

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. CHRISTIAN G. Larsen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 西堀宗樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. TAGO Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
35. TAMURA Hiroomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 高橋将文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 木村博昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kasahara Tadashi 笠原 忠

KASAHARA Tadashi 笠原 忠

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Investigation of JAK/STAT signalling and development of new reagents regulating JAK/STAT pathwaysPrincipal Investigator

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Investigation of abnormal cytokine signaling and the development of the drugs modulating these signalingPrincipal Investigator

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Role of TNF receptor-related factor 6(TRAF6) in the apoptosis induction and cytokine receptor signalingPrincipal Investigator

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Basic approaches for the development of immunomodulatory and anti-inflammatory drugs acting on the signaling moleculesPrincipal Investigator

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STUDY ON THE NEW ANTI-APOPTOTIC MOLECULES ANALYZED BY THE DNA MICROARRAY METHODSPrincipal Investigator

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接着斑キナーゼの抗アポトーシス作用とその機序の解析Principal Investigator

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Role of Anti-Apoptic Aaction of Focal Adhesion Kinase (FAK)Principal Investigator

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Kasahara Tadashi 笠原忠

KASAHARA Tadashi 笠原忠