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YAJIMA Yukiko  矢島 由紀子

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… Alternative Names

矢島 由起子  ヤジマ ユキコ

YAJIMA Yukio  矢島 由起子

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Researcher Number 60090114
External Links
Affiliation (based on the past Project Information) *help 2004: TOKYO MEDICAL AND DENTAL UNIVERCITY, SCHOLL OF BIOMEDICAL SCIENCE, PROFFECER
2003: Tokyo Metropolitan Organization for Medical Research, TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE, RESEARCHER, 研究員
2002 – 2003: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員
2001: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
1999: Molecular Biology, Researcher, 東京都臨床医学総合研究所, 研究員 … More
1999: 財団法人 東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
1996 – 1998: Dep. Molecular Biology The Tokyo Metropolitan Institute of Medical Science, 遺伝情報研究部門, 研究員
1997: (財)東京都臨床医学総合研究所, 遺伝情報研究部門, 研究員
1995: 東京都臨床医学研究所, 遺伝情報研究部門, 研究員
1995: The Tokyo Metropolitan Inst.of Med.Sci., Molecular Biology, Research Scientist, 遺伝情報研究部門, 研究員
1995: 財団法人東京都臨床医学総合研究所, 遺伝情報研究部門, 研究員
1994: The Tokyo Metropolitan Institutu of Medical Science, Dep.Molecular Biology, 遺伝情報研究部門, 研究員
1993 – 1994: 財団法人 東京都臨床医学総合研究所, 遺伝情報研究部門, 研究員
1992: The Tokyo Metropolitan Inst.Med.Sci. Dept.Mol.Biol, 遺伝情報研究部門, 研究員
1991: 東京都臨床医学総合研究所, 腫瘍細胞研究部門, 研究員
1988 – 1991: 東京都臨床医学総合研究所, 腫瘍細胞研究部門, 主任研究員
1988: The Tokyo Metropolitan Institute of Medical Science, Dept. Tumor Cell Biology, 腫瘍細胞研究室, 主任・研究員
1987 – 1988: 東京都臨床医学総合研究所, 腫瘍細胞研究室, 主任研究員 Less
Review Section/Research Field
Principal Investigator
内分泌・代謝学 / Metabolomics
Except Principal Investigator
内分泌・代謝学 / 物質生物化学 / Metabolomics / 応用薬理学・医療系薬学 / General medical chemistry / 代謝生物化学
Keywords
Principal Investigator
百日咳毒素 / ADP-ribosylation / αサブユニット / TRH / 分化 / 脂肪細胞 / pertussis toxin / GTP結合蛋白質 / βγサブユニット / VIP … More / ソマトスタチン / adenylate cyclase / phospholipase C / cholera toxin / Guanine nucleotide (GTP)-binding protein / TRH-receptor / down regulation / ADP-リボシル化 / GTPase / GTP結合蛋白室 / GTPγS / GTP / NaF / PIP_2 / IP_3 / IP_2 / IP_1 / イノシトール / Caチャンネル / ADPリボシル化 / アデニレートサイクラーゼ / ホスホリパーゼC / コレラ毒素 / TRH受容体 / GLUCOSE UPTAKE / INSULIN / INHIBITOR / CALPASTATIN / ADIPOCYTE DIFFERENTIATION / CALPAIN / ST-13 / 3T3-L1 / PPARγ / EBP / C / GLUT4 / カルパスタチン / インスリン / グルコーストランスポーター / カルパイン / Antidiabetic agent / differentiation / Goalpha / G proteins / adipocyte / 分化転写因子 / 抗糖尿病薬 / Go / G蛋白質 / pituitary cell / G proteins, / beta subuit, / alpha subunit, / Somatostatin, / ミリスチル酸 / βγ / 下垂体細胞 / beta gamma subunits / membranes / GH4CI cells / somatostatin / alpha subunits / GTP binding proteins (G proteins) / ミリスチン酸 / ADPーリボシル化 / Gi_2 / G蛋白 / 受容体刺激 / β^2サブユニット / 細胞膜 / Git_4C_1細胞 / GTP結合蛋白質(G蛋白質) … More
Except Principal Investigator
thyrotropin-releasing hormone / プロテインキナーゼC / Signal transduction / ホルモン / 細胞内情報伝達 / リン酸化 / ホルボールエステル / Phorbol ester / Hormone / Protein kinase C / PPAR / RXR / adipocyte / 脂肪細胞 / MARCKS / 分泌 / Phosphorylation / Pituitary clonal cells / Secretory mechanism / 脳下垂体培養細胞 / threonine kinase / Protein-serine / Calcium / セリン・スレオニンリン酸化酵素 / ホルボ-ルエステル / カルシウムイオン / ホルボ-ルエステル受容体 / プロテインキナ-ゼC / Diacylglycerol / Phospholipid / Phorbol ester receptor / ホルボールエメテル / ジアシルグリセロール / ホルボールエステル受容体 / ジアシルグリセロ-ル / リン脂質 / RXR antagonist / nuclear receptor / diabetes / アンタゴニスト / 生活習慣病 / PPARγ / RXRアンタゴニスト / 核内受容体 / 糖尿病 / ligand dependent transcription factor / differentiation / triterpene / insulin independent diabetes mellitus / インスリン非依存型糖尿病薬 / リガンド依存性転写制御因子 / 分化 / トリテルペン / インスリン非依存性糖尿病薬 / ischemia / apoptosis / secretion / Keratin / phosphorylation / protein kinase C / 中間径線維 / 虚血 / アポトーシス / 中間径繊維 / PKC Substrate / ホリボールエステル / Protein kinase C' / 分子生物学 / 下垂体細胞 / 遺伝子導入 / 分泌機構 / 分泌制御機構 / Down regulation / phorbol ester receptor / プロテインクナ-ゼC / セリン・スレオニリン酸化酵素 / ダウンレギュレ-ション Less
  • Research Projects

    (12 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (7 People)
  •  Identification of RXR antagonists and characterization of potent stimulation of ST 13 preadipocyte differentiation

    • Principal Investigator
      SATO Mayumi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  ROLE OF CALPAIN ON THE DIFFERENTIATION AND FUNCTION OF ADIPOCYTESPrincipal Investigator

    • Principal Investigator
      YAJIMA Yukiko
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Study on the phisiological substrates of PKCε

    • Principal Investigator
      AKITA Yoshiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Dehydrotrametenolic acid sensitize animal models of Non-Insulin dependent diabetes mellitus to insulin

    • Principal Investigator
      SATO Mayumi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH
  •  Study on the PKC isozymes-mediated mechanism in the regulated secretion.

    • Principal Investigator
      AKITA Yoshiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  The role of soluble GTP binding proteins in the differentiation of adipocytesPrincipal Investigator

    • Principal Investigator
      YAJIMA Yukiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Study on the roles of protein kinase Cisozymes in hormonal secretory process.

    • Principal Investigator
      AKITA Yoshiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  The study of the structure and the function of soluble GTP-binding protein which involved in the somatostatin receptorPrincipal Investigator

    • Principal Investigator
      YAJIMA Yukiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The Tokyo Metropolitan Institutu of Medical Science
  •  A new factor for cellular signal transduction-Studies of the structures and functions of soluble GTP binding proteinsPrincipal Investigator

    • Principal Investigator
      YAJIMA Yukiko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Study on the roles of protein kinase C isozymes in stimulus-responses

    • Principal Investigator
      AKITA Yoshiko
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Study of the roles of protein kinase C isozymes in the signal transduction

    • Principal Investigator
      AKITA Yoshiko
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  The study of the structure and the function of GTP-binding protein which involved in the mechanism of TRH-sensitive phospholipase C activationPrincipal Investigator

    • Principal Investigator
      YAJIMA Yukiko
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The Tokyo Metroplotan Institute of Medical Science

All 2004 2003 2002

All Journal Article Book

  • [Book] 脂肪細胞の分化とその機能におけるカルパインの役割2003

    • Author(s)
      矢島由紀子, 佐藤眞友美, 川島誠
    • Total Pages
      9
    • Publisher
      内分泌・糖尿病科
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Roles of calpain in the differentiation and function of adipocytes2004

    • Author(s)
      Yajima Y, Sato M, Kawashima S
    • Journal Title

      12^th International Congress of Endocrinology

      Pages: 547-551

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Nobel RXR antagonists enhance transactivaqtion of PPARγ and ST 13 preadipocyte differentiation.2004

    • Author(s)
      Sato M., A.Sugawara, N.Egawa, Y.Yajima, H.Kato, H.Kagechika
    • Journal Title

      12^<th> Internatinal Congress of Endocrinology

      Pages: 547-551

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Nobel RXR antagonists enhance transactivaqtion of PPARγ and ST 13 Preadipocyte differentiation.2004

    • Author(s)
      Sato M., A.Sugawara, N.Egawa, Y.Yajima, H.Kato, H.Kagechika
    • Journal Title

      Internatinal Congress of Endocrinology

      Pages: 547-551

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Roles of calpain in the differentiation and function of adipocytes2004

    • Author(s)
      Yajima Y, Sato M, Kawashima S
    • Journal Title

      12^<th> Internatinal Congress of Endocrinology

      Pages: 949-952

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Competitive RXR antagonists enhance transactivation of PPARγ and ST 13 preadipocyte differentiation 12^<th> International Congress of Endcrinology.2004

    • Author(s)
      MAYUMI SATO, AKIRA SUGAWARA, NAOTO EGAWA, YUKIKO YAJIMA, HIROYUKI KAGECHIKA.
    • Journal Title

      Portugal

      Pages: 831-904

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Mechanism of adult primitive mesenchymal ST-13 preadipocyte differ entiation2003

    • Author(s)
      Yukiko Yajima, Mayumi Sato, Michihiro Sumida et al.
    • Journal Title

      Endocrinology 144

      Pages: 2559-2565

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Mechanism of adult primitive mesenchymal ST-13 preadipocyte differentiation2003

    • Author(s)
      Yukiko Yajima, Mayumi Sato, Michihiro Sumida, Seiichi Kawashima.
    • Journal Title

      Endocrinology 144

      Pages: 2559-2565

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Dehydrotrametenolic acid induces preadipocyte differentiation and sensitizes animal models of NonInsulin-dependent Diabetes Mellitus to insulin.2002

    • Author(s)
      Sato M., Takaaki Tai, Yoshiki N., Yukiko Yajima et al.
    • Journal Title

      Biological & Pharmaceutical Bulletin 25

      Pages: 81-86

    • NAID

      110003638671

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • [Journal Article] Dehydrotrametenolic acid induces preadipocyte differentiation and sensitizes animal models of Nonlnsulin-dependent Diabetes Mellitus to insulin.2002

    • Author(s)
      Sato M., Takaaki Tai Yoshiki N.Yukiko Yajima, Seiichi Kawashima Keiji Tanaka
    • Journal Title

      Biological & Pharmaceutical Bulletin. 25(1)

      Pages: 81-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571118
  • 1.  AKITA Yoshiko (40124432)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  SATO Mayumi (50124459)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 3.  OHNO Shigeo (10142027)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  KAWASAKI Hiroshi (70169704)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KUSUBATA Kaori (80321884)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAHECHIKAK Hiroyuki (20177348)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  影近 弘之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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