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YOSHIDA Kouichi  吉田 幸一

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… Alternative Names

吉田 幸一  ヨシダ コウイチ

YOSHIDA Koichi  吉田 幸一

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Researcher Number 60117653
Other IDs
Affiliation (Current) 2025: 札幌医科大学, 医療人育成センター, 名誉教授
Affiliation (based on the past Project Information) *help 1999 – 2004: Sapporo Med.Univ.Sch.of Med.Prof., 医学部, 教授
2001: Sapporo Medical University, School of medicine, Professor, 医学部, 助教授
1999: 札幌医科大学, 医学部・附属がん研究所, 講師
1998 – 1999: 札幌医科大学, 医学部, 講師
1998: 札幌医科大学, 医学部附属がん研究所, 講師 … More
1998: 札幌医科大学, 附属がん研究所, 講師
1997: 札幌医科大学附属がん研究所, 講師
1996 – 1997: 札幌医科大学, 医学部・がん研究所, 講師
1989 – 1992: 札幌医科大学, がん研究所, 講師 Less
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Orthopaedic surgery / Virology
Except Principal Investigator
Surgical dentistry / Morphological basic dentistry / 病態科学系歯学(含放射線系歯学) / Pediatrics
Keywords
Principal Investigator
転写因子 / EWS / Ewing肉腫 / ETS transcription factor / chromosome translocation / mouse model of disease / ETS転写因子 / トランスジェニックマウス / Cre-loxP DNA組み換え / 染色体転座 … More / 肉腫 / アンチセンス / etsファミリー / E1AF / 浸潤 / telomerase / cre-loxP / EWS-FLI / fusion oncogene / Ewing sarcoma / ETS / PNET / 標的遺伝子 / テロメラーゼ / Cre-loxP / EWS-FLI1 / 融合がん遺伝子 / モデルマウス / cancer / transgenic mouse / cre-loxP DNA recombination / fusion gene / sarcoma / Cre-1oxP DNA組み換え / がん / 融合遺伝子 / 疾患モデルマウス / c-ets protooncogene / cDNA cloning / Transcription factor / Enhancer / ElA gene / Adenovirus / DNA結合蛋白 / アテツウィルス / cーetsがん遺伝子 / cDNAクロ-ニング / エンハンサ- / EIA遺伝子 / アデノウイルス / マトリックス プロテアーゼ / マトリックスプロテアーゼ / etsドメイン / 転写調節 / エンハンサー結合蛋白 / etsがん遺伝子 / アデノウイルスElA遺伝子 … More
Except Principal Investigator
p53 / p130 / Rb2 / 口腔癌 / E1AF / β-catenin / CHFR / cyclin D1 / HGF / Ad12E1A / Oral cancer / β-カテニン / Methylation / Cell adhesion factor / Gene / Oral squamous cell carcinoma / pRb2 / Snail / EMT / 口腔悪性黒色腫 / methylation / 細胞接着因子 / 遺伝子 / immunohistochemistry / gene mutation / epidermal growth factor receptor / oral squamous carcinoma / 遺伝子変異 / 蛋白発現 / 遺伝子突然変異 / EGFR / cyclinD1 / Genetic abnormality / 遺伝子異常 / DNA microarray / RNAサブトラクション法 / yeast two hybrid / ets がん遺伝子 / EIAF / 結合タンパク / etsがん遺伝子群転写因子 / DNAチップ / Degree of malignancy / Gene-technology / p16 / 悪性度 / 遺伝子工学 / 細胞同期 / がん細胞 / 細胞周期 / cip1> / p21^<waf1 / 細胞周期調節 / MMP / がん細胞浸潤 / 転写因子 / DNA hybridization / RT-PCR / PCR / Human cytomegalovirus / ドット・ブロット・ハイブリダイゼ-ション / RTーPCR法 / PCR法 / ポリメラ-ゼ連鎖反応 / DNA検出法 / ヒト・サイトメガロウイルス Less
  • Research Projects

    (13 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (16 People)
  •  Analysis of Ewing sarcoma using a transgenic mousePrincipal Investigator

    • Principal Investigator
      YOSHIDA Koichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Sapporo Medical University
  •  Development of assessrrment for degree of rnalignancy of oral cancer considering genetic change of Rb2/p130 related genes

    • Principal Investigator
      TANAKA Nobuyuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Department of Oral Surgery Sapporo Medical University School of Medicine
  •  Isolation of model mouse generating Ewing sarcoma and analysis of the mechanism of sarcoma-genesisPrincipal Investigator

    • Principal Investigator
      YOSHIDA Koichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Sapporo Medical University
  •  Alterations of cell adhesion-, growth- and transcription-relating genes in oral squamous cell carcinomas

    • Principal Investigator
      ODAJIMA Tetsuyo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Sapporo Medical University
  •  Analysis of genetic abnormality related to die invasion of oral cancer and its clinical appliance

    • Principal Investigator
      TANAKA Nobuyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Sapporo Medical University
  •  Analysis of malignancy of oral cancer and application of therapy for oral cancer by gene technology

    • Principal Investigator
      NOBUYUKI Tanaka
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Department of Oral Surgery, Sapporo Medical University School of Medicine
  •  Identification of targetgenes of E1AF using two hybrid system

    • Principal Investigator
      SHINDO Masanobu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  転写因子EIAF,EWS-E1AFの肉腫発症と浸潤への関与Principal Investigator

    • Principal Investigator
      吉田 幸一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  転写因子E1AFのがん細胞の浸潤活性の発現と細胞周期における役割

    • Principal Investigator
      小野 貢伸 (小野 貢信)
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Hokkaido University
  •  アデノウイルスエンハンサー統合性転写因子E/AFの発癌と浸潤・転移における役割Principal Investigator

    • Principal Investigator
      吉田 幸一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  E1Aエンハンサー結合性転写因子の構造と機能Principal Investigator

    • Principal Investigator
      吉田 幸一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  The Structure and Function of Adenovirus ElA Enhancer-Binding Protein.Principal Investigator

    • Principal Investigator
      YOSHIDA Koichi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Sapporo Medical College
  •  Development of Polymerase Chain Reaction Method for Detection of Human Cytomegalovirus DNA and Its Clinical Application.

    • Principal Investigator
      CHIBA Shunzo
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Sapporo Medical College

All 2005 2004 2003

All Journal Article

  • [Journal Article] E1AF degradation by a ubiquitin-proteasome pathway2005

    • Author(s)
      Takahashi A, Higashino F, Aoyagi M, Yoshida K, Itoh M, Kobayashi M, Totsuka Y, Kohgo T, Shindoh M.
    • Journal Title

      Biochem Biophys Res Commun 327

      Pages: 575-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591593
  • [Journal Article] E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters2005

    • Author(s)
      Izumiyama Y, Ohiro Y, Higashino F, Yoshida K, Taguchi K, Todo S, Kohgo T, Totsuka Y, Shindoh M.
    • Journal Title

      Oncol Rep. 13

      Pages: 715-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591593
  • [Journal Article] E1AF/PEA3 reduces the invasiveness of SiHa cervical cancer cells by activating serine proteinase inhibitor squanous cell carcinoma antigen2004

    • Author(s)
      Iwasaki M, Nishikawa A, Akutagawa N, Fujimoyo T, Teramoto M, Sakaguchi Y, Kato H, Ito M, Yoshida K, Kudo R.
    • Journal Title

      Exp Cell Res 299

      Pages: 525-532

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591593
  • [Journal Article] Induction of Tenascin-C by Tumor specific EWS-ETS fusion genes2003

    • Author(s)
      Watanabe G, Nishimori H, Irifune H, Sasaki Y, Ishida S, Zenbutsu H, Tanaka T, Kawaguchi S, Wada T, Hata J, Kusakabe M, Yoshida K, Nakamura Y, Tokino T.
    • Journal Title

      Genes Chromosomes and Cancer 36

      Pages: 224-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591593
  • [Journal Article] A tetraspanin-family protein, T-cell acute lymphoblastic leuhemia-associated antigen, is induced by the Ewing's sarcoma-Wilms'tumor 1 fusion protein of desmoplastic small round cell tumor2003

    • Author(s)
      Ito E, Honma R, Imai J-I, Azuma S, Kanno T, Mori S, Yoshie O, Nishio J, Iwasaki H, Yoshida K, Gohda J, Inoue J-I, Watanabe S, Semba K.
    • Journal Title

      Am J Pathol 163

      Pages: 2165-2172

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591593
  • [Journal Article] EWS/ETS Fusions activate telomerase in Ewing's tumors2003

    • Author(s)
      Takahashi A, Higashino F, Aoyagi M, Yoshida K, Itoh M, Kyo S, Ohno T, Taira T, Ariga H, Nakajima K, Hatta M, Kobayashi M, Sano H, Kohgo T, Shindo M.
    • Journal Title

      Cancer Res 63

      Pages: 8338-8344

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591593
  • 1.  NOBUYUKI Tanaka (50163548)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  ODAJIMA Tetsuyo (00177239)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  AKIRA Yamaguchi (10210353)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  藤永 恵 (10045338)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SHINDO Masanobu (20162802)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  WADA Takuro (00244369)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  CHIBA Shunzo (50045374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SUZUKI Nobuhiro (50216420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  YAMANAKA Tatsuru (70045508)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  YASUDA Motoaki (90239765)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KOBAYASH Masandu (80241321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HIGASHINO Fumihiro (50301891)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YAMADA Shunpei (60302890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SATOH Masaaki (40187232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  沢田 幸治 (80111128)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  小野 貢伸 (50281829)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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