YOSHIDA Kouichi 吉田幸一

… Alternative Names

吉田幸一ヨシダコウイチ

YOSHIDA Koichi 吉田幸一

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Researcher Number	60117653
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医療人育成センター, 名誉教授
Affiliation (based on the past Project Information) *help	1999 – 2004: Sapporo Med.Univ.Sch.of Med.Prof., 医学部, 教授 2001: Sapporo Medical University, School of medicine, Professor, 医学部, 助教授 1999: 札幌医科大学, 医学部・附属がん研究所, 講師 1998 – 1999: 札幌医科大学, 医学部, 講師 1998: 札幌医科大学, 医学部附属がん研究所, 講師 … More 1998: 札幌医科大学, 附属がん研究所, 講師 1997: 札幌医科大学附属がん研究所, 講師 1996 – 1997: 札幌医科大学, 医学部・がん研究所, 講師 1989 – 1992: 札幌医科大学, がん研究所, 講師 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery / Virology Except Principal Investigator Surgical dentistry / Morphological basic dentistry / 病態科学系歯学(含放射線系歯学) / Pediatrics
Keywords	Principal Investigator 転写因子 / EWS / Ewing肉腫 / ETS transcription factor / chromosome translocation / mouse model of disease / ETS転写因子 / トランスジェニックマウス / Cre-loxP DNA組み換え / 染色体転座 … More / 肉腫 / アンチセンス / etsファミリー / E1AF / 浸潤 / telomerase / cre-loxP / EWS-FLI / fusion oncogene / Ewing sarcoma / ETS / PNET / 標的遺伝子 / テロメラーゼ / Cre-loxP / EWS-FLI1 / 融合がん遺伝子 / モデルマウス / cancer / transgenic mouse / cre-loxP DNA recombination / fusion gene / sarcoma / Cre-1oxP DNA組み換え / がん / 融合遺伝子 / 疾患モデルマウス / c-ets protooncogene / cDNA cloning / Transcription factor / Enhancer / ElA gene / Adenovirus / DNA結合蛋白 / アテツウィルス / cーetsがん遺伝子 / cDNAクロ-ニング / エンハンサ- / EIA遺伝子 / アデノウイルス / マトリックスプロテアーゼ / マトリックスプロテアーゼ / etsドメイン / 転写調節 / エンハンサー結合蛋白 / etsがん遺伝子 / アデノウイルスElA遺伝子 … More Except Principal Investigator p53 / p130 / Rb2 / 口腔癌 / E1AF / β-catenin / CHFR / cyclin D1 / HGF / Ad12E1A / Oral cancer / β-カテニン / Methylation / Cell adhesion factor / Gene / Oral squamous cell carcinoma / pRb2 / Snail / EMT / 口腔悪性黒色腫 / methylation / 細胞接着因子 / 遺伝子 / immunohistochemistry / gene mutation / epidermal growth factor receptor / oral squamous carcinoma / 遺伝子変異 / 蛋白発現 / 遺伝子突然変異 / EGFR / cyclinD1 / Genetic abnormality / 遺伝子異常 / DNA microarray / RNAサブトラクション法 / yeast two hybrid / ets がん遺伝子 / EIAF / 結合タンパク / etsがん遺伝子群転写因子 / DNAチップ / Degree of malignancy / Gene-technology / p16 / 悪性度 / 遺伝子工学 / 細胞同期 / がん細胞 / 細胞周期 / cip1> / p21^<waf1 / 細胞周期調節 / MMP / がん細胞浸潤 / 転写因子 / DNA hybridization / RT-PCR / PCR / Human cytomegalovirus / ドット・ブロット・ハイブリダイゼ-ション / RTーPCR法 / PCR法 / ポリメラ-ゼ連鎖反応 / DNA検出法 / ヒト・サイトメガロウイルス Less

Analysis of Ewing sarcoma using a transgenic mousePrincipal Investigator
- Principal Investigator
  
  YOSHIDA Koichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Sapporo Medical University
Development of assessrrment for degree of rnalignancy of oral cancer considering genetic change of Rb2/p130 related genes
- Principal Investigator
  
  TANAKA Nobuyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Department of Oral Surgery Sapporo Medical University School of Medicine
Isolation of model mouse generating Ewing sarcoma and analysis of the mechanism of sarcoma-genesisPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Koichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Sapporo Medical University
Alterations of cell adhesion-, growth- and transcription-relating genes in oral squamous cell carcinomas
- Principal Investigator
  
  ODAJIMA Tetsuyo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Analysis of genetic abnormality related to die invasion of oral cancer and its clinical appliance
- Principal Investigator
  
  TANAKA Nobuyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Sapporo Medical University
Analysis of malignancy of oral cancer and application of therapy for oral cancer by gene technology
- Principal Investigator
  
  NOBUYUKI Tanaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Department of Oral Surgery, Sapporo Medical University School of Medicine
Identification of targetgenes of E1AF using two hybrid system
- Principal Investigator
  
  SHINDO Masanobu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  HOKKAIDO UNIVERSITY
転写因子EIAF,EWS-E1AFの肉腫発症と浸潤への関与Principal Investigator
- Principal Investigator
  
  吉田幸一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
転写因子E1AFのがん細胞の浸潤活性の発現と細胞周期における役割
- Principal Investigator
  
  小野貢伸 (小野貢信)
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Hokkaido University
アデノウイルスエンハンサー統合性転写因子E/AFの発癌と浸潤・転移における役割Principal Investigator
- Principal Investigator
  
  吉田幸一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
E1Aエンハンサー結合性転写因子の構造と機能Principal Investigator
- Principal Investigator
  
  吉田幸一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
The Structure and Function of Adenovirus ElA Enhancer-Binding Protein.Principal Investigator
- Principal Investigator
  
  YOSHIDA Koichi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Sapporo Medical College
Development of Polymerase Chain Reaction Method for Detection of Human Cytomegalovirus DNA and Its Clinical Application.
- Principal Investigator
  
  CHIBA Shunzo
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Sapporo Medical College

All 2005 2004 2003

All Journal Article

[Journal Article] E1AF degradation by a ubiquitin-proteasome pathway2005
- Author(s)
  Takahashi A, Higashino F, Aoyagi M, Yoshida K, Itoh M, Kobayashi M, Totsuka Y, Kohgo T, Shindoh M.
- Journal Title
  
  Biochem Biophys Res Commun 327
  
  Pages: 575-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591593
[Journal Article] E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters2005
- Author(s)
  Izumiyama Y, Ohiro Y, Higashino F, Yoshida K, Taguchi K, Todo S, Kohgo T, Totsuka Y, Shindoh M.
- Journal Title
  
  Oncol Rep. 13
  
  Pages: 715-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591593
[Journal Article] E1AF/PEA3 reduces the invasiveness of SiHa cervical cancer cells by activating serine proteinase inhibitor squanous cell carcinoma antigen2004
- Author(s)
  Iwasaki M, Nishikawa A, Akutagawa N, Fujimoyo T, Teramoto M, Sakaguchi Y, Kato H, Ito M, Yoshida K, Kudo R.
- Journal Title
  
  Exp Cell Res 299
  
  Pages: 525-532
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591593
[Journal Article] Induction of Tenascin-C by Tumor specific EWS-ETS fusion genes2003
- Author(s)
  Watanabe G, Nishimori H, Irifune H, Sasaki Y, Ishida S, Zenbutsu H, Tanaka T, Kawaguchi S, Wada T, Hata J, Kusakabe M, Yoshida K, Nakamura Y, Tokino T.
- Journal Title
  
  Genes Chromosomes and Cancer 36
  
  Pages: 224-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591593
[Journal Article] A tetraspanin-family protein, T-cell acute lymphoblastic leuhemia-associated antigen, is induced by the Ewing's sarcoma-Wilms'tumor 1 fusion protein of desmoplastic small round cell tumor2003
- Author(s)
  Ito E, Honma R, Imai J-I, Azuma S, Kanno T, Mori S, Yoshie O, Nishio J, Iwasaki H, Yoshida K, Gohda J, Inoue J-I, Watanabe S, Semba K.
- Journal Title
  
  Am J Pathol 163
  
  Pages: 2165-2172
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591593
[Journal Article] EWS/ETS Fusions activate telomerase in Ewing's tumors2003
- Author(s)
  Takahashi A, Higashino F, Aoyagi M, Yoshida K, Itoh M, Kyo S, Ohno T, Taira T, Ariga H, Nakajima K, Hatta M, Kobayashi M, Sano H, Kohgo T, Shindo M.
- Journal Title
  
  Cancer Res 63
  
  Pages: 8338-8344
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591593

1. NOBUYUKI Tanaka (50163548)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. ODAJIMA Tetsuyo (00177239)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. AKIRA Yamaguchi (10210353)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 藤永恵 (10045338)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHINDO Masanobu (20162802)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. WADA Takuro (00244369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. CHIBA Shunzo (50045374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUZUKI Nobuhiro (50216420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAMANAKA Tatsuru (70045508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YASUDA Motoaki (90239765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOBAYASH Masandu (80241321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIGASHINO Fumihiro (50301891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMADA Shunpei (60302890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SATOH Masaaki (40187232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 沢田幸治 (80111128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 小野貢伸 (50281829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOSHIDA Kouichi 吉田 幸一

吉田 幸一 ヨシダ コウイチ

YOSHIDA Koichi 吉田 幸一

Research Projects

Research Products

Co-Researchers

Analysis of Ewing sarcoma using a transgenic mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of assessrrment for degree of rnalignancy of oral cancer considering genetic change of Rb2/p130 related genes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation of model mouse generating Ewing sarcoma and analysis of the mechanism of sarcoma-genesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alterations of cell adhesion-, growth- and transcription-relating genes in oral squamous cell carcinomas

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of genetic abnormality related to die invasion of oral cancer and its clinical appliance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of malignancy of oral cancer and application of therapy for oral cancer by gene technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of targetgenes of E1AF using two hybrid system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写因子EIAF,EWS-E1AFの肉腫発症と浸潤への関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

転写因子E1AFのがん細胞の浸潤活性の発現と細胞周期における役割

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アデノウイルスエンハンサー統合性転写因子E/AFの発癌と浸潤・転移における役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

E1Aエンハンサー結合性転写因子の構造と機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

The Structure and Function of Adenovirus ElA Enhancer-Binding Protein.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Polymerase Chain Reaction Method for Detection of Human Cytomegalovirus DNA and Its Clinical Application.

Principal Investigator

Project Period (FY)

Research Category

Research Field

YOSHIDA Kouichi 吉田幸一

吉田幸一ヨシダコウイチ

YOSHIDA Koichi 吉田幸一