NOGUCHI Hiroshi 野口博司

… Alternative Names

野口博司ノグチヒロシ

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Researcher Number	60126141
Other IDs	https://orcid.org/0000-0003-4164-3144
External Links
Affiliation (Current)	2025: 日本薬科大学, 薬学部, 教授 2025: 静岡県立大学, 薬学部, 客員教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 日本薬科大学, 薬学部, 教授 2010 – 2015: 静岡県立大学, 薬学部, 教授 2001 – 2008: 静岡県立大学, 薬学部, 教授 1998 – 1999: 静岡県立大学, 薬学部, 教授 1995: University of Shizuoka School of Pharmaceutical Sciences, Professor, 薬学部, 教授 … More 1994: University of Tokyo, Faculty of Pharmaceutical Sciences, Lecturer, 薬学部, 講師 1991 – 1993: 東京大学, 薬学部, 助手 1989: 東京大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Living organism molecular science / Chemical pharmacy / Bioorganic chemistry / Natural medicines / Biomolecular chemistry Except Principal Investigator Chemical pharmacy / Collagenous pathology/Allergology / Life / Health / Medical informatics / Bioorganic chemistry / Living organism molecular science / Breeding science / Plant molecular biology/Plant physiology / Genetics/Genome dynamics
Keywords	Principal Investigator Rheum palmatum / flavonoid / squalene / Hopene synthase / triterpene / chalcone synthase / aloesone / polyketide / 生合成 / カルコン合成酵素 … More / クズ / CHS / 反応機構 / 酵素工学 / ゲノムDNA / イソフラボン / squalene : hopene cyclase / aloe / plant polyketide synthase / chalcone / decarboxylation / Benzalacetone synthase / Ipomoea / Stilbene synthase / Chalocone synthase / Plant polyketide synthase / Rheum Palmatum / Ipomoeapurpurea / 植物ポリケタイド / Rheum palmatun / 脱炭酸 / ベンザルアセトン合成酵素 / サツマイモ属 / スチルベン合成酵素 / 植物ポリケタイド合成酵素 / pinocembrin / naringenin / cinnamoyl-CoA / ρ-coumaroyl-CoA / Scutellaria baicalensis / Labiatae / Chalcone Synthase / シソ / ピノセンブリン / ナリンゲニン / 桂皮酸CoA / P-クマル酸CoA / コガネバナ / シソ科 / 大腸菌 / ケミカルバイオロジー / シンセティックバイオロジー / 光合成細菌 / シアノバクテリア / 生物合成 / 天然物 / コルジセピン / キノコ / 微生物 / 酵素化学 / 生物活性 / 抗生物質 / 物質生産 / 天然物化学 / OAC / polyketide synthase / Type III PKS / X線結晶構造解析 / 閉環酵素 / 植物 / タンパク質結晶構造解析 / ポリケタイド / バイオテクノロジー / プレニル基転移酵素 / テレトニン / 酵素 / テルペン環化酵素 / 分子多様性 / メロテルペノイド / biosynthesis / 生理活性 / ゲノム / flavoncid / chalcone synthas / エリレター / フラボノイド / アントシアン / プロトプラスト … More Except Principal Investigator ベーチェット病 / バイオテクノロジー / 遺伝子 / 植物 / 計算化学 / 3次元構造 / 三次元構造 / HLA / 東アジア / 物質生産 / 生合成 / 遺伝学 / ゲノム / 突然変異 / 逆遺伝学 / 免疫学 / 生体分子 / 構造法 / エピトープ探索 / ヒト主要組織適合抗 / 分子動力学計算 / フラグメント分子軌道法 / ドッキング計算 / 結合親和性予測 / エピトープ予測 / ヒト主要組織適合抗原 / 抗トポイソメラーゼⅠ抗体 / リンパ球増殖 / エピトープ / 抗トポイソメラーゼ１抗体 / 強皮症 / Ruthenium Porphyrin / Chiral Palladium Complex / Teleocidin Analogue / Chiral Lithium Amide / Calixarene Ester / Nuclear Magnetic Resonance / Solution Structure / Reactive Complex / 不斉Heck反応 / ルシジン / テレオシジン / カリックスアレン / 不斉アルドール反応 / ステロイドグリコシド / ベンゾラクタム / キラルリチウムアミド / 膜電位変化 / 核磁気共鳴スペクトル法 / ルテニウムポルフィリン / キラルパラジウム錯体 / テレオシジン類縁体 / キラルチリウムアミド / カリックスアレーンエステル / 核磁気共鳴 / 溶液構造 / 反応活性錯体 / Ca Antagonist / Flavone / Stillbene / Lignan / Anti-Allergy / Anti-PAF / Screening / Biologically Active Compound / Ca拮抗作用 / フラボン / スチルベン / リグナン / 抗アレルギー作用 / 抗パフ作用 / スクリーニング / 生物活性物質 / Secondary Metabolism of Microorganism / Transformation of Plant / Elicitor / Flavonoids / Chalcone Synthase / Production of Usefull compounds / Regulation of Metabolism / Biosynthesis / ザルコトキシン / パーオキシダーゼプロモーター / オキシドスクアレン閉環酵素 / カルコン合成還元酵素 / 二次代謝 / カルコン合成酵 / 菌類二次代謝 / 植物形質転換 / エリシター / フラボノイド / カルコン合成酵素 / 代謝制御 / IL-10 / 遺伝因子 / HLA-A*2601 / ブドウ膜炎 / IL-23R / 視力予後 / ３次元構造 / 国際情報交換 / MICA / 民族差 / IL23R / 疾患感受性遺伝子 / 酵素工学 / 機能制御 / 二次代謝酵素 / 遺伝的組換え / 育種学 / バイオテクノロジ / 形質転換 / イネ / 変異導入 / 相同組換え / 遺伝子ターゲティング / 組換え機構 / 分子遺伝 / MAb against bioactive compouud / Trans-genic plant / RAPD / Gene cloning / Biosynthetic enzyme / Medicinal Plant / アグロバクテリウム / グリチルリチン / カンゾウ / 毛状根 / ヘアリ-ル-ト Less

Susceptibility HLA alleles and the biological contribution of HLA for the pathogenesis of Behcet's disease or Scleroderma in East Asia
- Principal Investigator
  
  TAKEUCHI FUJIO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tokyo Seiei College
Development of comprehensive calculation method of HLA-peptide affinity and application to elucidation of the pathogenesis of Behcet's disease
- Principal Investigator
  
  Ishikawa Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  Kagoshima University
  Nagasaki University
Unprecedented enzyme-catalyzed generation of complexity in fumagillin-pseurotin biosynthesisPrincipal Investigator
- Principal Investigator
  
  Noguchi Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Natural medicines
- Research Institution
  Nihon Pharmaceutical University
  University of Shizuoka
Unification of biosynthetic pathways of a variety of plant polyketidesPrincipal Investigator
- Principal Investigator
  
  Noguchi Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  University of Shizuoka
Enzyme engineering for natural product biosynthesis
- Principal Investigator
  
  ABE IKURO
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo
Genetic contribution of HLA-A alleles for the pathogenesis of Behcet disease in East Asia
- Principal Investigator
  
  TAKEUCHI FUJIO
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  The University of Tokyo
Generating molecular diversity by the wide range of polyketide synthasesPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of Shizuoka
Reverse genetics and recombination
- Principal Investigator
  
  IIDA Shigeru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  University of Shizuoka
Application of gene targeting by homologous recombination as a biothecnological tool for rice functional genomics.
- Principal Investigator
  
  JOHZUKA Yasuyo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plant molecular biology/Plant physiology
- Research Institution
  University of Shizuoka
New mutagenesis approaches to study gene function in crop
- Principal Investigator
  
  IIDA Shigeru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Breeding science
- Research Institution
  University of Shizuoka
植物ポリケタイド生合成工学による分子多様性の創出Principal Investigator
- Principal Investigator
  
  野口博司
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of Shizuoka
Combinatorial Biosynthesis of Plant Polyketides and PolyprenoidsPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of Shizuoka
Formation of unnatural novel polyketides and isoprenoids from alternate and/or nonphysiological substrate by the engineered plant enzymesPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of Shizuoka
Functional diversity of chalcone synthasePrincipal Investigator
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  University of Shizuoka
薬用植物に関わる有用遺伝子の解析と応用への新展開
- Principal Investigator
  
  正山征洋
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
4' Deoxytpe Chalcone Synthase from Scutellaria baicalensisPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  University of Shizuoka
Structural Studies on Reactive Complexes for Highly Selective Organic Reactions
- Principal Investigator
  
  ODASHIMA Kazunori
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  University of Tokyo
薬用植物におけるフラボノイド類の区別的発現機構Principal Investigator
- Principal Investigator
  
  野口博司
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The University of Tokyo
The Research on the Production of Usefull Compounds by the Control of Regulations in the Biosynthesis of Secondary Metabolism
- Principal Investigator
  
  SANKAWA Ushio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  University of Tokyo
The Study on Seaching for the Biologically Active Compounds Containd in the Medicinal Plants
- Principal Investigator
  
  SANKAWA Ushio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  University of Tokyo
葉用植物におけるフラボノイド類生産の区別的発現Principal Investigator
- Principal Investigator
  
  野口博司
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  The University of Tokyo
薬用植物におけるフラボノイド類生産の基礎研究Principal Investigator
- Principal Investigator
  
  野口博司
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  The University of Tokyo
カンゾウ毛状根によるGlycyrrhiginの生産
- Principal Investigator
  
  SANKAWA Ushio
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  The University of Tokyo

[Journal Article] Biosynthesis of lagopodins in mushroom involves a complex network of oxidation reactions2019
- Author(s)
  Masuya Takahiro、Tsunematsu Yuta、Hirayama Yuichiro、Sato Michio、Noguchi Hiroshi、Nakazawa Takehito、Watanabe Kenji
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 17 Issue: 2 Pages: 234-239
- DOI
  10.1039/c8ob02814a
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06449, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-17H07002, KAKENHI-PROJECT-17K15265
[Journal Article] Lymphocyte proliferation induced by high-affinity peptides for HLA-B*51:01 in Behçet's uveitis2019
- Author(s)
  Kaburaki T, Nakahara H, Tanaka R, Okinaga K, Kawashima H, Hamasaki Y, Rungrotmongkol T, Hannongbua S, Noguchi H, Aihara M, Takeuchi F
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 9 Pages: 0222384-0222384
- DOI
  10.1371/journal.pone.0222384
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09398, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-19K09986
[Journal Article] Effects of Puerarin on the Ovariectomy-Induced Depressive-Like Behavior in ICR Mice and Its Possible Mechanism of Action2019
- Author(s)
  A. Tantipongpiradet, O. Monthakantirat, O. Vipatpakpaiboon, C. Khampukdee, K. Umehara, H. Noguchi, H. Fujiwara, K. Matsumoto, N. Sekeroglu, A. Kijjoa, Y. Chulikhit
- Journal Title
  
  MOLECULES
  
  Volume: 24 Issue: 24 Pages: 4569-4569
- DOI
  10.3390/molecules24244569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05840
[Journal Article] Interactions of HLA-DR and Topoisomerase I Epitope Modulated Genetic Risk for Systemic Sclerosis2019
- Author(s)
  S. Kongkaew, T. Rungrotmongkol, C. Punwong, H. Noguchi, F. Takeuchi, N. Kungwan, P. Wolschann, S. Hannongbua;
- Journal Title
  
  Scientific Reports
  
  Volume: 9(1) Issue: 1 Pages: 745-756
- DOI
  10.1038/s41598-018-37038-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397
[Journal Article] Correlation between the Potency of Flavonoids on Mushroom Tyrosinase Inhibitory Activity and Melanin Synthesis in Melanocytes2018
- Author(s)
  Promden Worrawat, Viriyabancha Wittawat, Monthakantirat Orawan, Umehara Kaoru, Noguchi Hiroshi, De-Eknamkul Wanchai
- Journal Title
  
  MOLECULES
  
  Volume: 23(6) Issue: 6 Pages: 1403-1403
- DOI
  10.3390/molecules23061403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05840
[Journal Article] α-Keto tetrahydrofuran lignan glucosides from the Bangladeshi medicinal plant Terminalia citrina inhibit estradiol (E2) induced proliferation in cancer cells2018
- Author(s)
  Muhit Md. Abdul、Umehara Kaoru、Noguchi Hiroshi
- Journal Title
  
  Phytochemistry
  
  Volume: 145 Pages: 161-167
- DOI
  10.1016/j.phytochem.2017.10.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16H05840
[Journal Article] Naphthalene glycosides in the Thai medicinal plant Diospyros mollis2017
- Author(s)
  Suwama Takaharu、Watanabe Keisuke、Monthakantirat Orawan、Luecha Prathan、Noguchi Hiroshi、Watanabe Kenji、Umehara Kaoru
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 72 Issue: 1 Pages: 220-229
- DOI
  10.1007/s11418-017-1134-1
- NAID
  40021456072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16H05840
[Journal Article] 2-Alkylquinolone alkaloid biosynthesis in the medicinal plantEvodia rutaecarpainvolves collaboration of two novel type III polyketide synthases2017
- Author(s)
  Matsui Takashi、Kodama Takeshi、Mori Takahiro、Tadakoshi Tetsuhiro、Noguchi Hiroshi、Abe Ikuro、Morita Hiroyuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Issue: 22 Pages: 9117-9135
- DOI
  10.1074/jbc.m117.778977
- NAID
  120006559815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16K18501, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-16H05840
[Journal Article] Design and synthesis of benzoacridines as estrogenic and anti-estrogenic agents2017
- Author(s)
  Torikai Kohei、Koga Rintaro、Liu Xiaohui、Umehara Kaoru、Kitano Tatsuya、Watanabe Kenji、Oishi Tohru、Noguchi Hiroshi、Shimohigashi Yasuyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 25 Issue: 20 Pages: 5216-5237
- DOI
  10.1016/j.bmc.2017.07.067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-15H01741, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-15K00557, KAKENHI-PROJECT-15K21210
[Journal Article] Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa2016
- Author(s)
  X. Yang, T. Matsui, T. Kodama, T. Mori, X. Zhou, F. Taura, H. Noguchi, I. Abe, H. Morita
- Journal Title
  
  FEBS J
  
  Volume: 283 Issue: 6 Pages: 1088-1106
- DOI
  10.1111/febs.13654
- NAID
  120006559813
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242067, KAKENHI-PROJECT-26560435, KAKENHI-PROJECT-26282210, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397
[Journal Article] Furofuran Lignan Glucosides with Estrogen-Inhibitory Properties from the Bangladeshi Medicinal Plant Terminalia citrina2016
- Author(s)
  Md. Abdul Muhit, Kaoru Umehara, Kanami Mori-Yasumoto, Hiroshi Noguchi†
- Journal Title
  
  Journal of Natural Products
  
  Volume: 79 Issue: 5 Pages: 1-10
- DOI
  10.1021/acs.jnatprod.5b01042
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460126, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397
[Journal Article] Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis2016
- Author(s)
  Tsuyoshi Yamamoto, Yuta Tsunematsu, Kodai Hara, Tomohiro Suzuki, Shinji Kishimoto, Hirokazu Kawaguchi, Hiroshi Noguchi, Hiroshi Hashimoto, Yi Tang, Kinya Hotta, & Kenji Watanabe
- Journal Title
  
  Angew Chem Int Ed Engl
  
  Volume: 印刷中 Issue: 21 Pages: 6207-6210
- DOI
  10.1002/anie.201600940
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291017, KAKENHI-PLANNED-16H06449, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-15K18491, KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16H04755
[Journal Article] Heptaoxygeneted xanthones as anti-austerity agents from Securidaca longepedunculata2016
- Author(s)
  Muhit Md A, Umehara K, Noguchi H
- Journal Title
  
  Fitoterapia
  
  Volume: 113 Pages: 74-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05840
[Journal Article] Five furofuranone lignan glucosides from Terminalia citrina inhibit in vitro E2-enhanced breast cancer cell proliferation2016
- Author(s)
  Muhit Md A, Umehara K, Noguchi H
- Journal Title
  
  Fitoterapia
  
  Volume: 113 Pages: 74-79
- DOI
  10.1016/j.fitote.2016.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00397
[Journal Article] Combinatorial Generation of Chemical Diversity by Redox Enzymes in Chaetoviridin Biosynthesis2016
- Author(s)
  Sato M, Winter JM, Kishimoto S, Noguchi H, Tang Yi, Watanabe K
- Journal Title
  
  Org. Lettr
  
  Volume: 18 Issue: 6 Pages: 1446-1449
- DOI
  10.1021/acs.orglett.6b00380
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-15KT0068
[Journal Article] Expression, purification, and crystallization of a plant polyketide cyclase from Cannabis sativa2015
- Author(s)
  X. Yang, T. Matsui, T. Mori, F. Taura, H. Noguchi, I. Abe, H. Morita
- Journal Title
  
  Acta Crystallographica Section F
  
  Volume: 71 Issue: 12 Pages: 1470-1474
- DOI
  10.1107/s2053230x15020385
- NAID
  120006389597
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242067, KAKENHI-PROJECT-26560435, KAKENHI-PROJECT-26282210
[Journal Article] Angiotensin-converting enzyme (ACE) inhibitory activity of Solanum torvum and isolation of a novel methyl salicylate glycoside2014
- Author(s)
  Simaratanamongkol A, Umehara K, Noguchi H, Panichayupakaranant P
- Journal Title
  
  J. of Functional Foods
  
  Volume: 11 Pages: 557-562
- DOI
  10.1016/j.jff.2014.08.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23406031
[Journal Article] Cytotoxic and immunomodulatory effects of polyhydroxyoctane isolated from Lentinus polychrous mycelia.2014
- Author(s)
  Fangkrathok N, et al.
- Journal Title
  
  J. Nat. Med
  
  Volume: 68 Issue: 2 Pages: 302-309
- DOI
  10.1007/s11418-013-0797-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-25460126
[Journal Article] Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesis.2014
- Author(s)
  Saruwatari, T., Yagishita, F., Mino, T., Noguchi, H., Hotta, K., Watanabe, K.
- Journal Title
  
  ChemBioChem
  
  Volume: 15 Issue: 5 Pages: 656-659
- DOI
  10.1002/cbic.201300751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09202, KAKENHI-PROJECT-23406031
[Journal Article] Effect of miroestrol on ovariectomy-induced cognitive impairment and lipid peroxidation in mouse brain2014
- Author(s)
  Monthakantirata O, Sukanoa W, Umehara K, Noguchi H, Chulikhita Y, Matsumoto K
- Journal Title
  
  Phytomedicine
  
  Volume: 21 Issue: 11 Pages: 1249-1255
- DOI
  10.1016/j.phymed.2014.06.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23406031
[Journal Article] Structure and Antioxidant Activity Relationships of Isoflavonoids from Dalbergia parviflora2014
- Author(s)
  Promden W, Monthakantirat O, Umehara K, Noguchi H, De-Eknamkul W
- Journal Title
  
  Molecules
  
  Volume: 19 Issue: 2 Pages: 2226-2237
- DOI
  10.3390/molecules19022226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-25460126
[Journal Article] Elucidation of Pseurotin Biosynthetic Pathway Points to Trans-Acting C-Methyltransferase: Generation of Chemical Diversity2014
- Author(s)
  Tsunematsu Y, Fukutomi M, Saruwatari T, Noguchi H, Hotta K, Tang Y, Watanabe K
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 53 Issue: 32 Pages: 8475-8479
- DOI
  10.1002/anie.201404804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23406031
[Journal Article] Non-heme dioxygenase catalyzes atypical oxidations to form the 6,6-quinolone core of viridicatin-type fungal alkaloid.2014
- Author(s)
  Ishikawa, N., Tanaka, H., Koyama, F., Noguchi, H., Wang, C. C., Hotta, K., Watanabe, K.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 53 Issue: 47 Pages: 12880-12884
- DOI
  10.1002/anie.201407920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10688, KAKENHI-PROJECT-23406031
[Journal Article] Identification of a new angiotensin-converting enzyme (ACE) inhibitor from Thai edible plants2014
- Author(s)
  Simaratanamongkol A, Umehara K, Noguchi H, Panichayupakaranant P
- Journal Title
  
  Food Chemistry
  
  Volume: 165 Pages: 92-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23406031
[Journal Article] Combinatorial generation of complexity by redox enzymes in the chaetoglobosin a biosynthesis2013
- Author(s)
  K. Ishiuchi, T. Nakazawa, F. Yagishita, T. Mino, H. Noguchi, K. Hotta, K. Watanabe
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 135 Pages: 7371-7377
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Targeted disruption of transcriptional regulators in Chaetomium globosum activates biosynthetic pathways and reveals transcriptional regulator-like behavior of aureonitol.2013
- Author(s)
  Nakazawa T, et al.
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 135 Issue: 36 Pages: 13446-13455
- DOI
  10.1021/ja405128k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-25242067
[Journal Article] Cloning and structure-function analyses of quinolone- and acridone-producing novel type III polyketide synthases from Citrus microcarpa2013
- Author(s)
  Mori, T., Shimokawa, Y., Matsui, T., Kinjo, K., Kato, R., Noguchi, H., Sugio, S., Morita, H., Abe, I.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 40 Pages: 28845-28858
- DOI
  10.1074/jbc.m113.493155
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-24710246, KAKENHI-PUBLICLY-25108710, KAKENHI-PROJECT-25242067
[Journal Article] Combinatorial Generation of Complexity by Redox Enzymes in the Chaetoglobosin A Biosynthesis2013
- Author(s)
  K. Ishiuchi, T. Nakazawa, F. Yagishita, T. Mino, H. Noguchi, K.a Hotta, K. Watanabe
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 19 Pages: 7371-7377
- DOI
  10.1021/ja402828w
- URL
  http://dx.doi.org/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054, KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-23880025, KAKENHI-PROJECT-25242067
[Journal Article] Spiro-carbon formation by different chemistry involving pathway crosstalk.2013
- Author(s)
  石川格靖, 他8名
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 9 Issue: 12 Pages: 818-825
- DOI
  10.1038/nchembio.1366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10688, KAKENHI-PROJECT-23310140, KAKENHI-PROJECT-23406031, KAKENHI-PUBLICLY-25108717, KAKENHI-PROJECT-25242067, KAKENHI-PROJECT-25640115
[Journal Article] Establishing a new methodology for genome mining and biosynthesis of polyketides and peptides through yeast molecular genetics2012
- Author(s)
  K. Ishiuchi, T. Nakazawa, T. Ookuma, S. Sugimoto, M. Sato, Y. Tsunematsu, N. Ishikawa, H. Noguchi, K. Hotta, H. Moriya, K. Watanabe
- Journal Title
  
  ChemBioChem
  
  Volume: 13(6) Pages: 846-854
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Overexpressing transcriptional regulator in Aspergillus oryzae activates a silent biosynthetic pathway to produce novel polyketide2012
- Author(s)
  T. Nakazawa, K. Ishiuchi, A. Praseuth, H. Noguchi, K. Hotta, K. Watanabe
- Journal Title
  
  ChemBioChem
  
  Volume: 13(6) Pages: 855-861
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Molecular cloning and characterization of copper amine oxidase from Huperzia serrate2012
- Author(s)
  J. Sun, H. Morita, G. Chen, H. Noguchi, I.Abe
- Journal Title
  
  Bioorg. & Med. Chem. Lettr.
  
  Volume: 22(18) Pages: 5784-5790
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Establishing a new methodology for genome mining and biosynthesis of polyketides and peptides through yeast molecular genetics2012
- Author(s)
  Ishiuchi, K., Nakazawa, T., Ookuma, T., Sugimoto, T., Sato, M., Tsunematsu, Y., Ishikawa, N., Noguchi, H., Hotta, K., Moriya, H., Watanabe, K.
- Journal Title
  
  ChemBioChem
  
  Volume: 13 Pages: 846-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Overexpressing transcriptional regulator in Aspergillus oryzae activates a silent biosynthetic pathway to produce novel polyketide2012
- Author(s)
  Nakazawa, T., Ishiuchi, K., Praseuth, A., Noguchi, H., Hotta, K., Moriya, H., Watanabe, K.
- Journal Title
  
  ChemBioChem
  
  Volume: 13 Pages: 855-861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Expression, purification and crystallization of an indole prenyltransferase from Aspergillus fumigatus2012
- Author(s)
  J. Chen, H. Morita, R. Kato, H. Noguchi, S. Sugio, I. Abe
- Journal Title
  
  Acta Cryst. Section F
  
  Volume: 68 Pages: 355-358
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Overexpressing transcriptional regulator in Chaetomium globosum activates a silent biosynthetic pathway: evaluation of shanorellin biosynthesis2012
- Author(s)
  Y. Tsunematsu, S. Ichinoseki, T. Nakazawa, N. Ishikawa, H. Noguchi, K. Hotta, K. Watanabe
- Journal Title
  
  J. of Antibiotics
  
  Volume: 65(7) Pages: 377-380
- NAID
  10030955543
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Induced production of mycotoxins in an endophytic fungus from the medicinal plant Datura stramonium L.2012
- Author(s)
  J. Sun, T. Awakawa, H. Noguchi, I. Abe
- Journal Title
  
  Bioorg. & Med. Chem. Lettr.
  
  Volume: 22(20) Issue: 18 Pages: 6397-6400
- DOI
  10.1016/j.bmcl.2012.07.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054, KAKENHI-PROJECT-23241068, KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-24710246
[Journal Article] Overexpressing transcriptional regulator in Aspergillus oryzae activates a silent biosynthetic pathway to produce novel polyketide2012
- Author(s)
  T. Nakazawa, K. Ishiuchi, A. Praseuth, H. Noguchi, K. Hotta, K. Watanabe
- Journal Title
  
  ChemBioChem.
  
  Volume: 13(6) Issue: 6 Pages: 855-861
- DOI
  10.1002/cbic.201200107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054, KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-23880025
[Journal Article] Molecular cloning and characterization of copper amine oxidase from Huperzia serrate2012
- Author(s)
  J. Sun, H. Morita, G. Chen, H. Noguchi, I. Abe
- Journal Title
  
  Bioorg. & Med. Chem. Lettr.,
  
  Volume: 22(18) Issue: 20 Pages: 5784-5790
- DOI
  10.1016/j.bmcl.2012.08.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054, KAKENHI-PROJECT-23406031
[Journal Article] Establishing a New Methodology for Genome Mining and Biosynthesis of Polyketides and Peptides through Yeast Molecular Genetics2012
- Author(s)
  石内勘一郎、佐藤道大, 他9名
- Journal Title
  
  Chembiochem
  
  Volume: 13 Issue: 6 Pages: 846-854
- DOI
  10.1002/cbic.201100798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01668, KAKENHI-PROJECT-22241054, KAKENHI-PROJECT-23310140, KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-23880025
[Journal Article] Prenylation of a Nonaromatic Carbon of Indolylbutenone by a Fungal Indole Prenyltransferase2012
- Author(s)
  J. Chen, H. Morita, T. Wakimoto, T. Mori, H. Noguchi, I. Abe
- Journal Title
  
  Organic Letters
  
  Volume: 14 (12) Pages: 3080-3083
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Expression, purification, and crystallization of an indole prenyltransferase from Aspergillus fumigatus2012
- Author(s)
  Chen, J., Morita, H., Kato, R., Noguchi, H., Sugio, S., Abe, I.
- Journal Title
  
  Acta Crystallogr., Sect.F : Struct.Biol.Cryst.Commun.
  
  Volume: 68 Issue: 3 Pages: 355-358
- DOI
  10.1107/s1744309112004964
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PROJECT-23406031
[Journal Article] Induced production of mycotoxins in an endophytic fungus from the medicinal plant Datura stramonium L.2012
- Author(s)
  J. Sun, T. Awakawa, H. Noguchi, I. Abe
- Journal Title
  
  Bioorg. & Med. Chem.Lettr
  
  Volume: 22(20) Pages: 6397-6400
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Flavonoid and stilbenoid production in callus cultures of Artocarpus lakoocha2012
- Author(s)
  S. Maneechai, W. De-Eknamkul, K. Umehara, H. Noguchi, K. Likhitwitayawuid
- Journal Title
  
  Phytochemistry
  
  Volume: 81 Pages: 42-49
- DOI
  10.1016/j.phytochem.2012.05.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases2011
- Author(s)
  Saruwatari, T., Praseuth, A.P., Sato, M., Torikai, K., Noguchi, H., Watanabe, K.
- Journal Title
  
  J.Antibiot.
  
  Volume: 64 Pages: 9-17
- NAID
  10030637198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases2011
- Author(s)
  T. Saruwatari, A. P Praseuth, M. Sato, K. Torikai, H. Noguchi, K. Watanabe
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 64 Pages: 9-17
- NAID
  10030637198
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Practical Synthesis of dopa derivative for biosynthetic production of potent antitumor natural products, Saframycins and Ecteinascidin 7432011
- Author(s)
  K. Torikai, T. Saruwatari, T. Kitano, T. Sano, A. Nakane, H. Noguchi, K. Watanabe
- Journal Title
  
  Letters In Organic Chemistry
  
  Volume: 8-10 Pages: 686-689
- NAID
  120005133055
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Enzymatic formation of an aromatic dodecaketide by engineered plant polyketide synthase2011
- Author(s)
  Wanibuchi, K., Morita, H., Noguchi, H., Abe, I.
- Journal Title
  
  Bioorg.Med.Chem.Lett.
  
  Volume: 21 Issue: 7 Pages: 2083-2086
- DOI
  10.1016/j.bmcl.2011.01.135
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068
[Journal Article] A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases2011
- Author(s)
  T.Saruwatari, A.P Praseuth, M.Sato, K.Torikai, H.Noguchi, K.Watanabe
- Journal Title
  
  Journal of Antibiotics
  
  Volume: 64 Pages: 9-17
- NAID
  10030637198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Enzymatic formation of an aromatic dodecaketide by engineered plant polyketide synthase2011
- Author(s)
  K. Wanibuchi, H. Morita, H. Noguchi, I. Abe
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 21 Pages: 2083-2086
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] The molecular basis of incomplete dominance at the A locus of CHS-D in the common morning glory, Ipomoea purpurea.2011
- Author(s)
  Y.Johzuka-Hisatomi, H.Noguchi, S.Iida
- Journal Title
  
  Journal of Plant Research
  
  Volume: 124 Pages: 299-304
- NAID
  10027868379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570049
[Journal Article] The molecular basis of incomplete dominance at the A locus of CHS-D in the common morning glory, Ipomoea purpurea2011
- Author(s)
  Y. Johzuka-Hisatomi, H. Noguchi and S. Iida
- Journal Title
  
  J. Plant Res
  
  Volume: 124 Pages: 299-304
- NAID
  10027868379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370001
[Journal Article] Practical synthesis of DOPA derivative for biosynthetic production of potent antitumor natural products, saframycins and ecteinascidin 7432011
- Author(s)
  Torikai, K., Saruwatari, T., Kitano, T., Sano, T., Nakane, A., Noguchi, H., Watanabe, K.
- Journal Title
  
  Letters In Organic Chemistry
  
  Volume: 8 Pages: 686-689
- NAID
  120005133055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] A struture-based mechanism fior benzalacetone synthase from Rheum palmatum2010
- Author(s)
  H. Morita, Y . Shimmokawa, M. Tanio, R.Kato, H. Noguchi, S. Sugio, T. Kohno, I. Abe
- Journal Title
  
  Proc. Nat. Acad. Sci. USA
  
  Volume: 107 Pages: 669-673
- Data Source
  KAKENHI-PROJECT-22241054
[Journal Article] Enzymatic Formation of Unnatural Novel Chalcone, Stilbene, and Benzophenone Scaffolds by Plant Type III Polyketide Synthase.2009
- Author(s)
  S. P. Shi, K. Wanibuchi, H. Morita, K. Endo, H. Noguchi, I. Abe
- Journal Title
  
  Organic. lett. 10
  
  Pages: 551-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310145
[Journal Article] Novel type III polyketide synthases from Aloe arborescens2009
- Author(s)
  Y, Mizuuchi, S. -P. Shi, K. Wanibuchi, A. Kojima, H. Morita, H. Noguchi, I. Abe
- Journal Title
  
  FEBS Journal 276
  
  Pages: 2391-2401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310145
[Journal Article] Enzymatic Synthesis of Plant Polyketides2008
- Author(s)
  S. P. Shi, H. Morita, K. Wanibuchil, Y. Mizuuchil, H. Noguchi, I. Abe
- Journal Title
  
  Current Organic Synthesis 5
  
  Pages: 250-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310145
[Journal Article] Structure function analysis of novel type III polyketide synthases from Arabidopsis thaliana.2008
- Author(s)
  Y. Mizuuchi, Y. Shimokawa, K. Wanibuchi, H. Noguchi, I. Abe
- Journal Title
  
  Biol. Pharm. Bull. 31
  
  Pages: 2205-2210
- NAID
  110007005016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310145
[Journal Article] Structure-Based Engineering of a Plant Type III Polyketide Synthase: Formation of an Unnatural Nonaketide Naphthopyrone2007
- Author(s)
  I. Abe, H. Morita, S. Oguro, H. Noma, K. Wanibuchi, N. Kawahara, Y. Goda, H. Noguchi, and T. Kohno
- Journal Title
  
  J. Am. Chem. Soc. 129,
  
  Pages: 5976-5980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310145
[Journal Article] An acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata.2007
- Author(s)
  K.Wanibuchi, P.Zhang, T.Abe, H.Morita, T.Kohno, G.Chen, H.Noguchi, I.Abe
- Journal Title
  
  FEBS Journal. 274
  
  Pages: 1073-1082
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic formation of unnatural cytokinin analogs by adenylate-isopentenyl-transferase from mulberry2007
- Author(s)
  I.Abe, H.Tanaka, T.Abe, H.Noguchi
- Journal Title
  
  Biochem.and Biophys. Res. Commun 355
  
  Pages: 795-800
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Site-directed mutagenesis of conserved aromatic residuesin rat squalene epoxidase2007
- Author(s)
  I.Abe, T.Abe, W.Lou, T.Masuoka, H.Noguchi
- Journal Title
  
  Biochem.and Biophys.Res.Commun. 352
  
  Pages: 259-263
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Site-directed mutagenesis of conserved aromatic residuesin rat squalene epoxidase2007
- Author(s)
  I.Abe, T.Abe, W.Lou, T.Masuoka, H.Noguchi
- Journal Title
  
  Biochem.and Biophys. Res. Commun 352
  
  Pages: 259-263
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] An acridon-producing novel multifunctional type III polyketide synthase from Huperzia serrata.2007
- Author(s)
  K.Wanibuchi, P.Zhang, T.Abe, H.Morita, T.Kohno, G.Chen, H.Noguchi, I.Abe
- Journal Title
  
  FEBS Journal. 274
  
  Pages: 1073-82
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Structural Insight into Chain-Length Control and Product Specificity of Pentaketide Chromone Synthase from Aloe arborescens2007
- Author(s)
  H. Morita, S. Kondo, S. Oguro, H. Noguchi, S. Sugio, I. Abe, and T. Kohno
- Journal Title
  
  Chemistry & Biology, 14,
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310145
[Journal Article] An acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata2007
- Author(s)
  K. Wanibuchi, P. Zhang, T. Abe, H. Morita, T. Kohno, G. Chen, H. Noguchi, I. Abe
- Journal Title
  
  FEBS J., 274(4)
  
  Pages: 1073-1082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310145
[Journal Article] Site-directed mutagenesis of conserved aromatic residuesin rat squalene epoxidase2007
- Author(s)
  I.Abe, T.Abe, W.Lou, T.Masuoka, H.Noguchi
- Journal Title
  
  Biochem. and Biophys. Res. Commun. 352
  
  Pages: 259-263
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic formation of unnatural cytokinin analogs by adenylate-isopentenyl-transferase from mulberry2007
- Author(s)
  I.Abe, H.Tanaka, T.Abe, H.Noguchi
- Journal Title
  
  Biochem. and Biophys. Res. Commun. 355
  
  Pages: 795-800
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Crystallization and preliminary crystallographic analysis of a novel plant type III polyketide synthase that produces pentaketide chromone2006
- Author(s)
  H.Morita, S.Kondo, T.Abe, H.Noguchi, S.Sugio I.Abe, T.Kohno
- Journal Title
  
  Acta Crystallographica Section F 62
  
  Pages: 899-901
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Engineered Biosynthesis of Plant Polyketides : Manipulation of Chalcone Synthase2006
- Author(s)
  I.Abe, T.Watanabe, H.Morita, T.Kohno, H.Noguchi
- Journal Title
  
  Org.Lett., 8(3)
  
  Pages: 499-502
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Crystallization and preliminary crystallographic analysis of a novel plant type III polyketide synthase that produces pentaketide chromone2006
- Author(s)
  H.Morita, S.Kondo, T.Abe, H.Noguchi, S.Sugio L.Abe, T.Kohno
- Journal Title
  
  Acta Crystallographica Section F COMMUN. 62
  
  Pages: 899-901
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic Formation of Quinolone Alkaloids by a Plant III Polyketide Synthase2006
- Author(s)
  I.Abe, T.Abe, K.Wanibuchi, H.Noguchi
- Journal Title
  
  Tetrahedron Letter. 47
  
  Pages: 8727-8730
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic formation of an unnatural methylated triketide by plant type III polyketide synthases2006
- Author(s)
  T.Abe, H.Noma, H.Noguchi, I.Abe
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 8727-8730
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic Formation of Quinolone Alkaloids by Plant Type III Polyketide Synthase2006
- Author(s)
  I.Abe, T.Abe, K.Wanibuchi, H.Noguchi
- Journal Title
  
  Org.Lett. 8(26)
  
  Pages: 6063-6065
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic formation of pyrrole-containing novel cyclic polyprenoids by bacterial squalene : hopene cyclase2006
- Author(s)
  H.Tanaka H.Noma H.Noguchi, I.Abe
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 3085-3089
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Engineered Biosynthesis of Plant Polyketides : Manipulation of Chalcone Synthase2006
- Author(s)
  T.Abe, T.Watanabe, H.Morita, T.Kohno, H.Noguchi
- Journal Title
  
  Org.Lett. 8(3)
  
  Pages: 499-502
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase2006
- Author(s)
  I.Abe, T.Watanabe, W.Lou, H.Noguchi
- Journal Title
  
  FEBS Journal 273
  
  Pages: 208-218
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic Formation of Quinolone Alkaloids by a Plant Type III Polyketide Synthase2006
- Author(s)
  I.Abe, T.Abe, K.Wanibuchi, H.Noguchi
- Journal Title
  
  Tetrahedron Letter. 47
  
  Pages: 8727-8730
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Engineered Biosynthesis of Plant Polyketides : Manipulation of Chalcone Synthase2006
- Author(s)
  I.Abe, T.Watanabe, H.Morita, T.Kohno, H.Noguchi
- Journal Title
  
  Organic. Letter 8
  
  Pages: 499-502
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Crystallization and preliminary crystallographic analysis of a novel plant type III polyketide synthase that produces pentaketide chromone2006
- Author(s)
  H.Morita, S.Kondo, T.Abe, H.Noguchi, S.Sugio, I.Abe, T.Kohno
- Journal Title
  
  Acta Crystallographica Section F 62
  
  Pages: 899-901
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] A Plant Type III Polyketide Synthase that Produces Pentaketide Chromone2005
- Author(s)
  I.Abe, Y.Utsumi, S.Oguro, H.Morita, Y.Sano, H.Noguchi
- Journal Title
  
  J.Am.Chem.Soc. 127(5)
  
  Pages: 1362-1363
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Chalcone Synthase Superfmaily of Type III Polyketide Synthases from Rhubarb (Rheum palmatum)2005
- Author(s)
  H.Tanaka, H.Noguchi, I.Abe
- Journal Title
  
  Proc.Japan Acad. 81
  
  Pages: 434-440
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Engineered Biosynthesis of Plant Polyketides : Chain Length Control in an Octaketide-Producing Plant Type III Polyketide Synthase2005
- Author(s)
  I.Abe, S.Oguro, Y.Utsumi, Y.Sano, H.Noguchi
- Journal Title
  
  J.Am.Chem.Soc. 127(36)
  
  Pages: 12709-12716
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] A Plant Type III Polyketide Synthase that Produces Pentaketide Chromone2005
- Author(s)
  I.Abe, Y.Utsumi, S.Oguro, H, Morita, Y.Sano, H.Noguchi
- Journal Title
  
  J.Am.Chem.Soc. 127(5)
  
  Pages: 1362-1363
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Engineered Biosynthesis of Plant Polyketides : Chain Length Control in an Octaketide-Producing Plant Type III Polyketide Synthase2005
- Author(s)
  I.Abe, S.Oguro, Y.Utsumi, Y.Sano, H.Noguchi
- Journal Title
  
  J.Am.Chem.Soc. 127 (36)
  
  Pages: 12709-12716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic Formation of Indole-Containing Unnatural Cyclic Polyprenoids by Bacterial Squalene : Hopene Cyclase2005
- Author(s)
  H.Tanaka, H.Noguchi, I.Abe
- Journal Title
  
  Organic.Lett. 7(26)
  
  Pages: 5873-5876
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Engineered Biosynthesis of Plant Polyketides : Chain Length Control in an Octaketide-Producing Plant Type III Polyketide Synthase2005
- Author(s)
  I.Abe, S.Oguro, Y.Utsumi, Y.Sano, H.Noguchi
- Journal Title
  
  J. Am. Chem. Soc. 127(36)
  
  Pages: 12709-12716
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Japanese morning glory dusky mutants displaying reddish-brown or purplish-gray flowers are deficient in a novel glycosylation enzyme for anthocyanin biosynthesis, UDP-glucose : anthocyanidin 3-O-glucoside-2"-O- glucosyltransferase, due to 4-bp insertions in the gene2005
- Author(s)
  Y.Morita, A.Hoshino, Y.Kikuchi, H.Okuhara, E.Ono, Y.Tanaka, Y.Fukui, N.Saito, E.Nitasaka, H.Noguchi, S.Iida
- Journal Title
  
  The Plant Journal 42
  
  Pages: 353-363
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] A Plant Type III Polyketide Synthase that Produces Pentaketide Chromone2005
- Author(s)
  I.Abe, Y.Utsumi, S.Oguro, H.Morita, Y.Sano, H.Noguchi;
- Journal Title
  
  J.Am.Chem.Soc. 127(5)
  
  Pages: 1362-1363
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Chalcone Synthase Superfmaily of Type III Polyketide Synthases from Rhubarb (Rheum palmatum)2005
- Author(s)
  H.Tanaka, H.Noguchi, I.Abe
- Journal Title
  
  Proc. Japan Acad. 81
  
  Pages: 434-440
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Japanese morning glory dusky mutants displaying reddish-brown or purplish-gray flowers are deficient in a novel glycosylation enzyme for anthocyanin biosynthesis, UDP-glucose : anthocyanidin 3-O-glucoside -2" -O- glucosyltransferase, due to 4-bp insertions in the gene2005
- Author(s)
  Y.Morita, A.Hoshino, Y.Kikuchi, H.Okuhara, E.Ono, Y.Tanaka, Y.Fukui, J.Saito, E.Nitasaka, H.Noguchi, S.Iida
- Journal Title
  
  The Plant Journal 42
  
  Pages: 353-363
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] A Plant Type III Polyketide Synthase that Produces Pentaketide Chromone2005
- Author(s)
  I.Abe, Y.Utsumi, S.Oguro, H.Morita, Y.Sano, H.Noguchi
- Journal Title
  
  J. Am. Chem. Soc. 127(5)
  
  Pages: 1362-1363
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] A Plant Type III Polyketide Synthase that Produces Pentaketide Chromone2005
- Author(s)
  T.Abe, Y.Utsumi, S.Oguro, H.Morita, Y.Sano, H.Noguchi
- Journal Title
  
  J.Am.Chem.Soc. 127(5)
  
  Pages: 1362-1363
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Chalcone Synthase Superfmaily of Type III Polyketide Synthases from Rhubarb (Rheum palmatum)2005
- Author(s)
  I.Abe, T.Watanabe, H.Noguchi
- Journal Title
  
  Proc.Japan Acad. 81, Ser. B
  
  Pages: 434-440
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310130
[Journal Article] Enzymatic Cyclization of 22,23-Dihydro-2, 3-Oxidosqualene into Euph-7-en-3-ol and Bacchar-12-en-3-ol by Recombinant β-Amyrin Synthase2004
- Author(s)
  Abe, I., Sakano, Y., Tanaka, H., Lou, W., Noguchi, H., Shibuya, M., Ebizuka, Y.
- Journal Title
  
  J. Am. Chem. Soc. 126(11)
  
  Pages: 3426-3427
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Probing Biosynthesis of Plant Polyketides with Synthetic N-Acetylcysteamine Thioesters2004
- Author(s)
  Oguro, S., Akashi, T., Ayabe, S., Noguchi, H., Abe, I.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 325(2)
  
  Pages: 561-567
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic formation of long-chain polyketide pyrones by plant type III polyketide synthases2004
- Author(s)
  Abe, I., Watanabe, T., Noguchi, H.
- Journal Title
  
  Phytochem. 65
  
  Pages: 2447-2453
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.)2004
- Author(s)
  Sakano, Y., Okada, Y., Matsunaga, A., Suwama, T., Kaneko, T., Ito, K., Noguchi, H., Abe, I.
- Journal Title
  
  Phytochemistry 65
  
  Pages: 2439-2446
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic formation of long-chain polyketide pyrones by plant type III polyketide synthases2004
- Author(s)
  I.Abe, T.Watanabe, H.Noguchi
- Journal Title
  
  Phytochem. 65
  
  Pages: 2447-2453
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] 1-Methylidenesqualene and 25-Methylidenesqualene as Active-Site Probes for Bacterial Squalene: Hopene Cyclase2004
- Author(s)
  Tanaka, H., Noguchi, H., Abe, I.
- Journal Title
  
  Organic. Lett. 6(5)
  
  Pages: 803-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic Formation of An Unnatural Novel Tetracyclic Sesterterpene by β-Amyrin Synthase2004
- Author(s)
  H.Noma, H.Tanaka, H.Noguchi, M.Shibuya, Y.Ebizuka, I.Abe
- Journal Title
  
  Tetrahedron Lett. 45
  
  Pages: 8299-8301
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Probing Biosynthesis of Plant Polyketides with Synthetic N-Acetylcysteamine Thioesters2004
- Author(s)
  S.Oguro, T.Akashi, S.Ayabe, H.Noguchi, I.Abe
- Journal Title
  
  Biochem.Biophys.Res.Commun. 325(2)
  
  Pages: 561-567
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic Cyclization of 26- and 27- Methylidenesqualene to Novel Unnatural C31 Polyprenoids by Squalene: Hopene Cyclase2004
- Author(s)
  Tanaka, H., Noguchi, H., Abe, I.
- Journal Title
  
  Tetrahedron Letters 45(15)
  
  Pages: 3093-3096
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic Formation of An Unnatural Novel Tetracyclic Sesterterpene by β-Amyrin Synthase2004
- Author(s)
  H.Noma, H.Tanaka, H.Noguchi, M.Shibuva, Y.Ebizuka, I.Abe
- Journal Title
  
  Tetrahedron Lett. 45
  
  Pages: 8299-8301
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] The First Plant Type III Polyketide Synthase that Catalyzes Formation of Aromatic Heptaketide2004
- Author(s)
  Abe, I., Utsumi, Y., Oguro, S., Noguchi, H.
- Journal Title
  
  FEBS Letters 562(1)
  
  Pages: 171-176
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic reactions by five chalcone synthase homologs from hop (Humulus lupulus L.)2004
- Author(s)
  Okada, Y., Sano, Y., Kaneko, T., Abe, I., Noguchi, H., Ito, K.
- Journal Title
  
  Biosci. Biotech. Biochem. 68(5)
  
  Pages: 1142-1145
- NAID
  10013144980
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic Formation of An Unnatural Novel Tetracyclic Sesterterpene by β-Amyrin Synthase2004
- Author(s)
  Noma, H., Tanaka, H., Noguchi, H., Shibuya, M., Ebizuka, Y., Abe, I.
- Journal Title
  
  Tetrahedron Lett. 45
  
  Pages: 8299-8301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Mechanism and Stereochemistry of Enzymatic Cyclization of 24, 30-Bisnor- 2,3- oxidosqualene by Recombinant β-Amyrin Synthase2004
- Author(s)
  Abe, I., Sakano, Y., Sodeyama, M., Tanaka, H., Noguchi, H., Shibuya, M., Ebizuka, Y.
- Journal Title
  
  J. Am. Chem. Soc. 126
  
  Pages: 6880-6881
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic reactions by five chalcone synthase homologs from hop (Humulus lupulus L.)2004
- Author(s)
  Y.Sakano, Y.Okada, A.Matsunaga, T.Suwama, T.Kaneko, K.Ito, H.Noguchi
- Journal Title
  
  Biosci.Biotech.Biochem. 68(5)
  
  Pages: 1142-1145
- NAID
  10013144980
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] The First Plant Type III Polyketide Synthase that Catalyzes Formation of Aromatic Heptaketide2004
- Author(s)
  I.Abe, Y.Utsumi, S.Oguro, H.Noguchi
- Journal Title
  
  FEBS Letters 562(1)
  
  Pages: 171-176
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Characterization of Folding Pathways of the Type-1 and Type-2 Periplasmic Binding Proteins MglB and ArgT2003
- Author(s)
  Kashiwagi, K., Shiba, K., F.-Kobayashi, K., Noda, T., Nishikawa, K, Noguchi, H.
- Journal Title
  
  J. Biochem. 133
  
  Pages: 371-376
- NAID
  130003418081
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Enzymatic Formation of Unnatural Novel Polyketides from Alternate Starter and Non-physiological Extension Substrate by Chalcone Synthase2003
- Author(s)
  Abe, I., Takahashi, Y., Lou, W., Noguchi, H.
- Journal Title
  
  Organic Lett. 5
  
  Pages: 1277-1280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Journal Article] Site-directed Mutagenesis of Benzalacetone Synthase: The-Role-of PHE215 in Plant Type III Polyketide Synthases2003
- Author(s)
  Abe, I., Sano, Y., Takahashi, Y., Noguchi, H.
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 25218-25226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310153
[Presentation] Biosynthesis of plant polyphenol2016
- Author(s)
  Noguchi H
- Organizer
  The 6th International Conference on Natural Products for Health and Beauty (NATPRO6)
- Place of Presentation
  Pullman Hotel（KhonKaen, Thailand）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00397
[Presentation] Biosynthesis of plant polyphenol2016
- Author(s)
  Noguchi　H
- Organizer
  The 6th International Conference on Natural Products for Health and Beauty (NATPRO6)
- Place of Presentation
  Pullman Hotel　（KhonKaen, Thailand
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05840
[Presentation] Green Tea Polyphenol Inhibits Key Enzyme in Cholesterol Biosynthesis2016
- Author(s)
  Noguchi　H
- Organizer
  20th World Congress on Clinical Nutrition
- Place of Presentation
  Rama Garden Hotel （Bangkok, Thailand)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05840
[Presentation] アサ由来ポリケタイド閉環酵素のX線結晶構造解析2016
- Author(s)
  森田洋行，楊新美，松井崇，児玉猛，森貴裕，周暁希，野口博司，阿部郁朗
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25242067
[Presentation] Green Tea Polyphenol Inhibits Key Enzyme in Cholesterol Biosynthesis2016
- Author(s)
  Noguchi H
- Organizer
  20th World Congress on Clinical Nutrition
- Place of Presentation
  Rama Garden Hotel（Bangkok, Thailand）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00397
[Presentation] アサ由来ポリケタイド閉環酵素のX線結晶構造解析2015
- Author(s)
  森田洋行，楊新美，松井崇，児玉猛，周暁希，森貴裕，野口博司，阿部郁朗
- Organizer
  酵素工学研究会第74回講演会
- Place of Presentation
  東京
- Year and Date
  2015-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-25242067
[Presentation] Precursor-directed biosynthesis of unnatural novel alkaloids by using a plant type III polyketide synthase obtained from Evodia rutaecarpa2015
- Author(s)
  Ito T., Kodama T., Noguchi H., Abe I., Morita H
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-25242067
[Presentation] Structure-function analyses of two novel plant type III polyketide synthases obtained from medicinal plant Evodia rutaecarpa2015
- Author(s)
  Kodama T., Matsui T., Mori T., Tadakoshi T., Noguchi H., Abe I., Morita H
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242067
[Presentation] タイ薬用植物由来イソフラボノイドの抗デング熱作用2014
- Author(s)
  梅原　薫、左　一八、安倍智子、Orawan Monthakantirat、Wanchai De-Eknamkul、Noorsaadah Abd. Rahman、鈴木　隆、野口博司
- Organizer
  第20回天然薬物の開発と応用シンポジウム
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-23406031
[Presentation] Estrogenic/ anti-estrogenic constituents from Bangladesh medicinal plant, Pothos scandens.2014
- Author(s)
  Md. Abdul Muhit, Kaoru Umehara, Hiroshi Noguchi
- Organizer
  11th Japan-China International Symposium on Health Sciences (Shizuoka)
- Place of Presentation
  日本平ホテル（静岡県・静岡市）
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-23406031
[Presentation] Establishing a new methodology for genome mining and biosynthesis of natural products through fungal molecular genomics.2012
- Author(s)
  Hiroshi Noguchi
- Organizer
  International Congress on Natural Products Research
- Place of Presentation
  New York, (US)
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] Establishing a new methodology for genome mining and biosynthesis of natural products through fungal molecular genomics2012
- Author(s)
  H. Noguchi
- Organizer
  International Congress on Natural Products Research
- Place of Presentation
  New York, (US)
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] Biosynthesis of natural products through a fungal molecular genetics2012
- Author(s)
  T. Nakazawa, T. Ookuma, S. Sugimoto, S. Ichinoseki, Y. Gotanda, N. Ishikawa, Y. Tsunematsu, K. Ishiuchi, H. Noguchi, K. Watanabe
- Organizer
  Philipps-Universitat Marburg
- Place of Presentation
  Germany
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] Biosynthesis of Natural Products Through a Fungal Molecular Genetics2012
- Author(s)
  T. Nakazawa, T. Ookuma, S. Sugimoto, S. Ichinoseki, Y. Gotanda, N. Ishikawa, Y. Tsunematsu, K. Ishiuchi, H. Noguchi, K. Watanabe
- Organizer
  11th European Conference on Fungal Genetics.
- Place of Presentation
  Philipps-Universität Marburg (Germany)
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] T. Nakazawa, K. Ishiuchi, K. Hotta, H.Noguchi, H. Moriya, K. Watanabe2011
- Author(s)
  T. Nakazawa, K. Ishiuchi, K. Hotta, H.Noguchi, H. Moriya, K. Watanabe
- Organizer
  8th AFMC International Medicinal Chemistry Symposium "Frontier of Medicinal Science"
- Place of Presentation
  KEIO PLAZA HOTEL TOKYO(東京)
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] A chemical library by engineered plant polyketide synthase2010
- Author(s)
  H. Noguchi
- Organizer
  The 1st Current Drug Development International Conference
- Place of Presentation
  Phuket (Thailand)
- Year and Date
  2010-05-07
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] Combinatorial biosynthesis of unnatural novel prenylated alkaloids. Abstract2010
- Author(s)
  J.Chen, H.Noguchi
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu (HW US)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] Combinatorial biosynthesis of unnatural novel prenylated alkaloids. Abstrac2010
- Author(s)
  J. Chen, H. Noguchi
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu (HW US)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22241054
[Presentation] Crystal Structure of a Plant Type III Polyketide Synthase that Produce Benzalacetone2008
- Author(s)
  H. Morita, M. Tanio, S. Kondo, R. Kato, K. Wanibuchi, H. Noguchi, S. Sugio, I. Abe, T. Kohno
- Organizer
  5th International Conference on Plant Metabolomics
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19310145
[Presentation] セイヨウオトギリソウ由来ポリケタイド合成酵素の機能解析2008
- Author(s)
  下川良彦, 野口博司, 阿部郁朗
- Organizer
  第54回日本薬学会東海支部大会講演要旨集、p. 40
- Place of Presentation
  名古屋
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19310145
[Presentation] 結晶構造に基づくアロエ由来ポリケタイド合成酵素の機能改変2008
- Author(s)
  鰐渕清史, 野口博司, 阿部郁朗
- Organizer
  第54回日本薬学会東海支部大会講演要旨集、p. 32
- Place of Presentation
  名古屋
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19310145
[Presentation] 植物由来新規III型ポリケタイド合成酵素の結晶構造の解明と機能改変2007
- Author(s)
  森田洋行、鰐渕清史、近藤伸、小黒聡史、野間久史、野口博司、杉尾成俊、河野俊之、阿部郁朗
- Organizer
  第49回天然有機化合物討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19310145
[Presentation] Anti Dengue and Leishmanicidal Activities of Flavonoids from Thai Medicinal plants
- Author(s)
  Kaoru Umehara, Tomoko Abe, Kazuya Hidari, Takashi Suzuki, Kanami Mori-Yasumoto, Setsuko Sekita, Orawan Monthakantirat, Wanchai De-Eknamkul, Hiroshi Noguchi
- Organizer
  27th International Conference on Polyphenol
- Place of Presentation
  名古屋大学(愛知県・名古屋市）
- Year and Date
  2014-09-02 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-23406031
[Presentation] MICA-TM peptide selectively bind to HLAs associated with Behcet’s disease
- Author(s)
  Kongkaew S, Yodmanee P, Kaiyawet N, Meeprasert A, Rungrotmongkol T, Kaburaki T, Noguchi H, Takeuchi F, Kungwan N, Hannongbua S
- Organizer
  XII International Conference on Bioinformatics, Computational Biology and Biomedical Engineering, Kyoto
- Place of Presentation
  京都ブライトンホテル　(京都府・京都市)
- Year and Date
  2014-11-13 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-23406031
[Presentation] Structure function relationship of type III polyketide synthase
- Author(s)
  Hiroshi Noguchi
- Organizer
  The 3rd Current Drug Development International Conference
- Place of Presentation
  Ao Nang (タイ）
- Year and Date
  2014-05-01 – 2014-05-03
- Invited
- Data Source
  KAKENHI-PROJECT-23406031

1. UMEHARA KAORU (40185070)

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2. ABE IKURO (40305496)

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3. WATANABE Kenji (50360938)

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4. IIDA Shigeru (30012777)

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5. JOHZUKA Yasuyo (60517887)

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6. SANKAWA Ushio (60012613)

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7. TAKEUCHI FUJIO (70154979)

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8. KUSHIRO Testuo (80373299)

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9. KOBAYASHI Hirokazu (80170348)

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10. MORITA Hiroyuki (20416663)

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11. SHIBUYA Masaaki (50170923)

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12. Ishikawa Takeshi (80505909)

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13. 蕪城俊克 (00280941)

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14. SATO Toshitsugu

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16. ISHIZAKI Kimitsune (00452293)

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17. WAKIMOTO Toshiyuki (70363900)

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18. AWAKAWA Takayoshi (80609834)

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19. MATSUDA Yudai (10720766)

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20. SUGIO Shigetoshi (10537343)

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21. KABURAKI Toshikatsu (70343126)

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22. HARIHARA Shinji (40198932)

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23. KUWATA Shoji (00241993)

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24. HAGINO Noboru (40466769)

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25. HAKAMATSUKA Takashi (60221488)

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26. FUJII Isao (70181302)

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27. ODASHIMA Kazunori (30152507)

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28. HIGUCHI Tsunehiko (50173159)

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29. SODEOKA Mikiko (60192142)

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30. ENDO Yasuyuki (80126002)

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31. 正山征洋 (70037604)

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32. 水上元 (30128219)

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33. 池上文雄 (90159608)

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34. 斉藤和季 (00146705)

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35. 海老塚豊 (90107384)

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36. 橋本博 (40336590)

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37. 濱崎洋一郎 (10180936)

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38. 籏持淳 (90172923)

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39. IMANARI Mamoru

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40. PARK Myoung Hee

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41. SONG Yeong Wook

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42. YU Chia-Li

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43. WORAWIT Louthrenoo

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44. SUPOT Hannongbua

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45. SA-NGA Pattanakitsul

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46. PHAN Thi Hoan

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47. AMR H Sawalha

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48. YASUMOTO Kanami

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49. 石川格靖

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# of Collaborated Products: 2 results
50. 佐藤道大

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# of Collaborated Products: 2 results

NOGUCHI Hiroshi 野口 博司

野口 博司 ノグチ ヒロシ

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Unprecedented enzyme-catalyzed generation of complexity in fumagillin-pseurotin biosynthesisPrincipal Investigator

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Unification of biosynthetic pathways of a variety of plant polyketidesPrincipal Investigator

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Generating molecular diversity by the wide range of polyketide synthasesPrincipal Investigator

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植物ポリケタイド生合成工学による分子多様性の創出Principal Investigator

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Combinatorial Biosynthesis of Plant Polyketides and PolyprenoidsPrincipal Investigator

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Formation of unnatural novel polyketides and isoprenoids from alternate and/or nonphysiological substrate by the engineered plant enzymesPrincipal Investigator

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Functional diversity of chalcone synthasePrincipal Investigator

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NOGUCHI Hiroshi 野口博司

野口博司ノグチヒロシ

[Journal Article] Lymphocyte proliferation induced by high-affinity peptides for HLA-B*51:01 in Behçet's uveitis2019