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NODA Masatoshi  野田 公俊

ORCIDConnect your ORCID iD *help
Researcher Number 60164703
External Links
Affiliation (based on the past Project Information) *help 2016 – 2018: 千葉大学, 大学院医学研究院, 教授
2013 – 2016: 千葉大学, 医学(系)研究科(研究院), 教授
2007 – 2012: Chiba University, Dept. of Molecular Infectiology, Professor
2006: 千葉大学, 大学院医学研究院, 教授
2001 – 2005: CHIBA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE, PROFESSOR, 大学院・医学研究院, 教授 … More
1990 – 2000: Chiba University, School of Medicne, Professor, 医学部, 教授
1995: 千葉大学, 医科部, 教授
1989: Chiba University, School of Medicine Assistant Professor, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Bacteriology (including Mycology) / Bacteriology (including Mycology) / 細菌学
Except Principal Investigator
Bacteriology (including Mycology) / 細菌学 / Gastroenterology / Bacteriology (including mycology) / Bacteriology (including Mycology) / Digestive surgery / Neurology / Surgical dentistry / 病態科学系歯学(含放射線系歯学)
Keywords
Principal Investigator
ARI / ARF / コレラ毒素 / ADP-リボシル化 / ADP-ribosyltransferase / コレラ / O157 : H7 / Vero cells / cytotoxin / MRSA … More / Cholera toxin / NAD / GTP結合蛋白質 / 志賀毒素 / 腸管出血性大腸菌 / 毒素 / O157 / SubAB / pregnenolone / Ca^<2+> / 低分子量GTP結合蛋白 / 3量体GTP結合蛋白 / ADP-ribosylation / Helicobacter pyroli / Polyphenols / Enteroheamorrhagic Eschelicia coli O157 / Vacuolating toxin (VacA) / Vero toxin / Botulinum toxin / 無毒化剤 / ボツリヌス菌 / 腸管出血生大腸菌O157 / コレラ菌 / ベロ毒素(VT) / コレラ毒素(CT) / ABサブユニット毒素 / ABサブユニット / レセプター / Helicobacter pylori / ポリフェノール / 腸管出血性大腸菌O157 / 空砲化致死毒(VacA) / ベロ毒素 / ボツリヌス毒素 / ganglioside GM1-like structure / Ganalioside GM1 / Haemophilus influenza / Guillain-Barre syndrome / ガングリオシドGQ1b / 神経障害 / リポ多糖 / ガングリオシドGM / 抗カングリオシドGM1 / 上気道炎 / 呼吸器感染症 / Haemophilus influenzae / 急性下痢症 / Campylobacter jejuni / ギラン・バレー症候群(GBS) / サイトトキシン / ガングリオシドGMl様構造 / ガングリオシドGMl / Heaemophilus influenzae / ギランバレー症候群 / rabbit ileal loop / fluid accumulation / lethal toxicity / virulence factor / Shiga-like(Vero)toxin / 桂皮 / 大黄 / 抗VT活性 / Shiga-like toxin / O157:H7 / 白子蛋白 / ケイヒ / 蛋白合成阻害作用 / 致死活性 / ベロ細胞 / VT2 / VT1 / lethal activity / RSAaUV^r cells / CHO cells / 水様性下痢 / 心臓毒 / HL-サイトトキシン / 即時型致死活性 / コレラ様下痢 / cAMP / Gs / Cholera / ADPーribosyltransferase / サイクリッチAMP / アデニル酸シクラ-ゼ / histidine / DEPC / ADP-リボース / Gsα / Protein kinase C / GTP-binding protein / Phospholipase C / Phospholipase A_2 / Leukocidin S and F comp. / Staphylococcal alpha-toxin / ホスファチジルイノシト-ル代謝系 / ホスホリパ-ゼA_2 / ADPリボシルトランスフェラ-ゼ / PIPキナ-ゼ / PIキナ-ゼ / PI代謝 / プロティンキナ-ゼC / ホスホリパ-ゼC / ADPーリボシルトランスフェラ-ゼ / ロイコシジン / α毒素 / 黄色ブドウ球菌 / NO / lipid-raft / 阻害剤 / 取り込み機構 / オートファジー / lipid-raft / 酸化ストレス / ストレスグラニュール / 細胞死 / 一酸化窒素 / 小胞体ストレス / Bcl-2 / ERストレス / BiP / サブチラーゼサイトトキシン / 受容体 / アポトーシス / ER ストレス / 0157 / STEC / AB成分毒素ファミリー / Stx / EHEC / GSα / 低分子量GTP結合蛋白質 / 3量体GTP結合蛋白質 / ADP-リボシル化活性 … More
Except Principal Investigator
細菌毒素 / 腸管出血性大腸菌 / GM1 / ADP-ribosylation / GTP-binding protein / ADPリボシル化反応 / アルコール / LPS / リポ多糖 / Pseudomonas cepatia / 黄色ブドウ球菌 / 病原性 / 細菌 / 病原因子 / 細菌感染症 / ADP-リボシル化 / ADPリボシル化 / NO還元酵素 / 重症化 / NOセンサー / 一酸化窒素還元酵素 / NO消去酵素 / 一酸化窒素 / HL-60 cells / Phospholipase C / Phospholipase A_2 / ADP-ribosyltransferase / Leukocidin S and F comp. / Staphylococcal alpha-toxin / NAD / ホスファチジルイノシトール / ホスファチジルコリン / ホスホリパーゼC / ホスホリバーゼA_2 / ロイコシジンF成分 / ロイコシジンS成分 / ブドウ球菌α毒素 / ヒト前骨髄性白血病HL-60細胞 / GTP結合蛋白質 / ADPリボシル転移酵素 / ホスホリパ-ゼC / ホスホリパ-ゼA_2 / ロイコシジンS及びF成分 / α毒素 / surgery / protein / adenosine 5' -diphosphate (ADP)-ribosylation / colorectal cancer / ADP-リポシル化 / 外科 / 蛋白質 / 大腸癌 / gangliosides / Haemophilus influenzae / Guillain-Barre syndrome / インフルエンザ / 神経内科学 / 神経免疫学 / 末梢神経 / インフルエンザ桿菌 / 糖脂質 / ヘモフィルス・インフルエンザ / ギラン・バレー症候群 / ANTI-OXIDANT / DIFFEFRRENTIATION / GROWTH / COCCOID / PYLORI / HRLICOBACTRR / 分子量 / 還元剤 / 増殖・分化 / 球状化 / coccoid / ピロリ菌 / pylori / Helicobacter / BACTERIAL INFECTION / ETIOLOGIC AGENT / BACTERIAL TOXIN / ADP-RIBOSYLTRANSFERASE / HELICOBACTER PYLORI / ADP-リボシル化酵素 / ヘリコバクター・ピロリ / Phosphoglucomutase / Alcohol / フォスフォグルコムターゼ / フィースファグルコムターゼ / フォスフォグルコチターゼ / alcohol / GTP結合タン白 / GTP結合蛋白 / Cytotoxic toxins / Exotoxin / Lipopolysaccharide / Endotoxin / Bacterial toxins / GPIアンカー / 蛋白毒素 / 細胞傷害 / 細胞毒 / 外毒素 / 内毒素 / Clostridium perfringens / Staphylococcus aureus / ibrio vulnificus / Vibrio parahaemolyticus / Erythrocytes / Cytolysin / Hemolysin / Vibrio vulnificus / ウェルシュ菌 / 腸炎ビブリオ / 赤血球 / 細胞溶解毒 / 溶血毒素 / 薬剤耐性 / 嫌気性 / 動物実験 / 宿主防御機構 / 嫌気条件 / 抗菌薬 / 増殖性 / 活性酸素種 / 嫌気状態 / 志賀毒素 / 志賀様毒素 / 最近 / 分泌 / 感染症 / 活性酸素 / 走化性 / 好中球 / シグナル伝達 / サイトカイン / 抗毒素 / 難治性顎骨骨髄炎 / 生体内輸送 / 侵入 / 定着 / 防禦反班 / 細胞内情報伝達定着 / 毒素 / cytotoxic / 骨芽細胞 / 慢性下顎骨骨髄炎 / Streptococcus mitis / ブドウ球菌 / アルコール性肝障害 / Gたん白 Less
  • Research Projects

    (30 results)
  • Research Products

    (136 results)
  • Co-Researchers

    (45 People)
  •  A study on the acquisition mechanism of pathogenicity in intact NO reductase-type EHEC

    • Principal Investigator
      Shimizu Takeshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      Chiba University
  •  Establishment of absolute anaerobic biology for pathogenic evaluation of EHEC

    • Principal Investigator
      Shimizu Takeshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      Chiba University
  •  Elucidation of the pathogenic reinforcement action of enterohemorrhagic Escherichia coli produced SubABPrincipal Investigator

    • Principal Investigator
      Noda Masatoshi
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  Elucidation of Shiga-toxigenic Escherichia coli produced Subtilase cytotoxin-induced cell damage mechanism.Principal Investigator

    • Principal Investigator
      NODA Masatoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  Studies on the SubAB toxin, its target organs, and its quick identificationPrincipal Investigator

    • Principal Investigator
      NODA Masatoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  Analysis of secretion system of virulence factor in gram-negative bacteria

    • Principal Investigator
      SHIMIZU Takeshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  Elucidation of a potential role of poly-ADP-ribosylation in the carcinogenesis or development of human colorectal carcinoma and its application for the diagnosis or trteatment of human colorectal carcinoma

    • Principal Investigator
      NABEYA Yoshihiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  H.pylori由来酸性ホスファターゼの宿主応答制御機序の解析

    • Principal Investigator
      YAHIRO Kinnosuke
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  Development of a quick neutralization therapy for the diseases caused by bacterial toxinsPrincipal Investigator

    • Principal Investigator
      NODA Masatoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  Development of a quick diagnosis of Haemophilus influenzea Which induces Guillain- Barre syndrome.Principal Investigator

    • Principal Investigator
      NODA Masatoshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      CHIBA UNIVERSITY
  •  The features of saccharides on the LPS of Hemophilus influenzae which elicits Guillain-Barre syndrome

    • Principal Investigator
      HATTORI Takamichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      CHIBA UNIVERSITY
  •  EFFECT OF ENVIRONMENTAL FACTORS AND ANTI-OXIDANTS ON LIFE CYCLES OF HELICOBACTER PYLORI

    • Principal Investigator
      MIYAKE Masami
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      CHIBA UNIVERSITY
  •  難治性慢性骨髄炎の骨芽細胞障害性因子に対する抗毒素を用いた新治療法の開発

    • Principal Investigator
      丹沢 秀樹
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Chiba University
  •  病原細菌由来ビルレンス因子と宿主細胞の相互連関との解析

    • Principal Investigator
      中村 信一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kanazawa University
  •  ADP-RIBOSYLTRANSFERASE OF HELIOBACTER PYLORI

    • Principal Investigator
      HIRAYAMA Toshiya
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Nagasaki University
  •  Screening and purification of Shiga-like (Vero)toxin inhibitorsPrincipal Investigator

    • Principal Investigator
      NODA Masatoshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba Unibersity
  •  口腔内連鎖球菌の産生する骨芽細胞障害因子の精製とその病原性に関する研究

    • Principal Investigator
      佐藤 研一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Chiba University
  •  Signal transduction in hepatocytes-Long-term alcohol effects on small G-proteins

    • Principal Investigator
      NOMURA Fumio
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  低分子G蛋白ARF及びARIによるコレラ毒素のADP-リボシル化活性の制御Principal Investigator

    • Principal Investigator
      野田 公俊
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  黄色ブドウ球菌の新たなADP-リボシル化毒素について

    • Principal Investigator
      MIYAKE Masami
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  低分子G蛋白ARF及びARIによるコレラ毒素のADP-リボシル化活性の制御Principal Investigator

    • Principal Investigator
      野田 公俊
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  Novel cytotoxins purified from methicillin-resistant staphylococcus aureusPrincipal Investigator

    • Principal Investigator
      NODA Masatoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  Effects of long-term alcohol intake on G Protein mediated callvlar events in hepatocytes

    • Principal Investigator
      NOMURA Fumio
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  コレラ毒素によるGsのADP-リボシル化を制御する低分子量GTP結合蛋白質ARF及びARIPrincipal Investigator

    • Principal Investigator
      野田 公俊
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  肝細胞の情報伝達系とアルコール-GTP結合たん白のADPリボシル化反応に及ぼす長期飲酒の影響に関する研究

    • Principal Investigator
      NOMURA Fumio
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Molecular mechanisms of bacterial toxins on host cells

    • Principal Investigator
      NAKANO Masayasu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      細菌学
    • Research Institution
      Jichi Medical School
  •  REGULATION SYSTEM OF ADP-RIBOSYLTRANSFERASE ACTIVITY OF CHOLERA TOXING BY ARE AND ARI :Principal Investigator

    • Principal Investigator
      NODA Masatoshi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      Chiba University
  •  Molecular Genetic Analysis and Mechanism of Action of Bacterial Cytolysins

    • Principal Investigator
      SHINODA Sumio
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      細菌学
    • Research Institution
      Okayama University
  •  Studies on the effects of ADP-ribosyltransferase activities of staphylococcal cytolytic toxins on the signal transduction in cell membrane.Principal Investigator

    • Principal Investigator
      NODA Masatoshi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Chiba University
  •  Studies on the analysis of molecular structure and signal-transduction mechanism of the cell-membrane damaging by staphylococcal cytolytic toxins.

    • Principal Investigator
      KATO Iwao
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      Chiba University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Patent

  • [Book] Handbook of Proteolytic Enzymes, 3^<rd> Edition [Cytotoxin SubAB (Chapter 694)]2013

    • Author(s)
      Yahiro, K., J. Moss, and M. Noda
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] Mechanism of inhibition of Shiga-toxigenic Escherichia coli SubAB cytotoxicity by steroids and diacylglycerol analogues2018

    • Author(s)
      Yahiro Kinnosuke、Nagasawa Sayaka、Ichimura Kimitoshi、Takeuchi Hiroki、Ogura Kohei、Tsutsuki Hiroyasu、Shimizu Takeshi、Iyoda Sunao、Ohnishi Makoto、Iwase Hirotaro、Moss Joel、Noda Masatoshi
    • Journal Title

      Cell Death Discovery

      Volume: 4 Issue: 1 Pages: 22-22

    • DOI

      10.1038/s41420-017-0007-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08486, KAKENHI-PROJECT-16K08770, KAKENHI-PROJECT-17K10019, KAKENHI-PROJECT-18K07133, KAKENHI-PROJECT-16K08771
  • [Journal Article] Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157.2017

    • Author(s)
      K. Ichimura, Shimizu. T, Takeuchi. H, Matsumoto. A, Yahiro. K, Noda. M,
    • Journal Title

      MicrobiologyOpen

      Volume: 印刷中 Issue: 4 Pages: 1-17

    • DOI

      10.1002/mbo3.461

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390104, KAKENHI-PROJECT-26670208, KAKENHI-PROJECT-16K08771, KAKENHI-PROJECT-16K15315, KAKENHI-PROJECT-16K08770
  • [Journal Article] The surface sensor NlpE of enterohemorrhagic Escherichia coli contributes to regulation of the type III secretion system and flagella by the Cpx response to adhesion2016

    • Author(s)
      Takeshi Shimizu, Kimitoshi Ichimura and Masatoshi Noda
    • Journal Title

      Infect. Immun.

      Volume: 84 Issue: 2 Pages: 537-549

    • DOI

      10.1128/iai.00881-15

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670208, KAKENHI-PROJECT-24390104
  • [Journal Article] 腸管出血性大腸菌感染症の現状と病原性2016

    • Author(s)
      八尋錦之助、野田公俊
    • Journal Title

      化学療法の領域

      Volume: 32 Pages: 70-76

    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] Subtilase cytotoxin produced by locus of enterocyte effacement-negative Shiga-toxigenic Escherichia coli induces stress granule formation2016

    • Author(s)
      H. Tsutsuki, K. Yahiro, K. Ogura, K. Ichimura, S. Iyoda, M. Ohnishi, S. Nagasawa, K. Nagasawa, J. Moss, M. Noda
    • Journal Title

      Cellular Microbiology

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] An evolutionary analysis of nitric oxide reductase gene norV in enterohemorrhagic Escherichia coli O1572015

    • Author(s)
      Takeshi Shimizu, Shinichiro Hirai, Eiji Yokoyama, Kimitoshi Ichimura and Masatoshi Noda
    • Journal Title

      Infection, Genetics and Evolution

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Journal Article] An evolutionary analysis of nitric oxide reductase gene norV in enterohemorrhagic Escherichia coli O1572015

    • Author(s)
      Takeshi Shimizu, Shinichiro Hirai, Eiji Yokoyama, Kimitoshi Ichimura and Masatoshi Noda
    • Journal Title

      Infect. Genet. Evol.

      Volume: 33 Pages: 176-181

    • DOI

      10.1016/j.meegid.2015.04.027

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Journal Article] DAP1, a Negative Regulator of Autophagy, Controls SubAB-Mediated Apoptosis and Autophagy2014

    • Author(s)
      Yahiro, K. Tsutsuki, H. Ogura, K. Nagasawa, S. Moss, J. Noda, M.
    • Journal Title

      Infect Immun

      Volume: 82 Issue: 11 Pages: 4899-4908

    • DOI

      10.1128/iai.02213-14

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] Uptake of Shiga-toxigenic Escherichia coli SubAB by HeLa cells requires an actin- and lipid raft-dependent pathway2014

    • Author(s)
      Nagasawa, S. Ogura, K. Tsutsuki, H. Saitoh, H. Moss, J. Iwase, H. Noda, M. Yahiro, K.
    • Journal Title

      Cell Microbiol

      Volume: 16 Issue: 10 Pages: 1582-1601

    • DOI

      10.1111/cmi.12315

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] 腸管出血性大腸菌による食中毒重症化メカニズム2013

    • Author(s)
      清水 健、野田 公俊
    • Journal Title

      日本医事新報

      Volume: 4614 Pages: 98-99

    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] 病原細菌のAB5型トキシンの作用機構等に関する研究2013

    • Author(s)
      野田 公俊
    • Journal Title

      日本細菌学雑誌

      Volume: 68 Pages: 299-311

    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] 腸管出血性大腸菌の重症化要因2013

    • Author(s)
      清水 健、野田 公俊
    • Journal Title

      感染・炎症・免疫

      Volume: 43 Pages: 74-76

    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] Regulation of Subtilase cytotoxin (SubAB)-induced cell death by a PKR-like endoplasmic reticulum kinase (PERK)-dependent proteasome pathway in HeLa cells2012

    • Author(s)
      Yahiro, K.Tsutsuki, H.Ogura, K.Nagasawa, S.Moss, J.Noda, M.
    • Journal Title

      Infect Immun

      Volume: (In press) Issue: 5 Pages: 1803-1814

    • DOI

      10.1128/iai.06164-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] 腸管出血性大腸菌による食中毒重症化メカニズム2012

    • Author(s)
      清水 健、野田公俊
    • Journal Title

      日本医事新報

      Volume: 4614 Pages: 98-99

    • Data Source
      KAKENHI-PROJECT-24390104
  • [Journal Article] Subtilase cytotoxin enhances Escherichia coli survival in macrophages by suppression of nitric oxide production through the inhibition of NF-κB activation2012

    • Author(s)
      Tsutsuki H, Yahiro K, Suzuki K, Suto A, Ogura K, Nagasawa S, Ihara H, Shimizu T, Nakajima H, Moss J, Noda M
    • Journal Title

      Infect Immun

      Volume: 80 Issue: 11 Pages: 3939-51

    • DOI

      10.1128/iai.00581-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591432, KAKENHI-PROJECT-23591458, KAKENHI-PROJECT-24390104
  • [Journal Article] The nitric oxide reductase of enterohemorrhagic Escherichia coli plays an important role for the survival within macrophages2012

    • Author(s)
      Shimizu T, Tsutsuki H, Matsumoto A, Nakaya H, Noda M
    • Journal Title

      Mol Microbiol

      Volume: 85 Issue: 3 Pages: 492-512

    • DOI

      10.1111/j.1365-2958.2012.08122.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117008, KAKENHI-PROJECT-23390053, KAKENHI-PROJECT-24390104, KAKENHI-PROJECT-24659111
  • [Journal Article] Regulation of Subtilase cytotoxin (SubAB)-induced cell death by a PKR-like endoplasmic reticulum kinase (PERK)-dependent proteasome pathway in HeLa cells2012

    • Author(s)
      Yahiro, K., H. Tsutsuki, K. Ogura, S. Nagasawa, J. Moss, M. Noda
    • Journal Title

      Infect Immun. In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] Fatal hemonhage induced by subtilase cytotoxin from Shiga-toxigeaic Eschenchia coli.2011

    • Author(s)
      Furukawa T., Yahiro K., Tsuji A. B., Terasaki Y., Morinaga N., Miyazaki M., Fukuda Y., Saga T., Moss J., Noda M.
    • Journal Title

      Microb Pathog.

      Volume: 50 Pages: 159-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] Fatal hemorrhage induced by subtilase cytotoxin from Shiga-toxigenic Escherichia coli2011

    • Author(s)
      Furukawa, T., K. Yahiro, A. B. Tsuji, Y. Terasaki, N. Morinaga, M. Miyazaki, Y. Fukuda, T. Saga, J. Moss, M. Noda
    • Journal Title

      Microb Pathog

      Volume: 50 Pages: 159-167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] Characterization of Cholix toxin-induced apoptosis in HeLa cells2011

    • Author(s)
      Ogura K, Yahiro K, Tsutsuki H, Nagasawa S, Yamasaki S, Moss J, Noda M
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 43 Pages: 37207-15

    • DOI

      10.1074/jbc.m111.246504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127, KAKENHI-PROJECT-22790401
  • [Journal Article] Identification of subtilase cytotoxin (SubAB) receptors whose signaling, in association with SubAB-induced BiP cleavage, is responsible for apoptosis in HeLa cells.2011

    • Author(s)
      Yahiro K., Satoh M., Morinaga N., Tsutsuki H., Ogura K., Nagasawa S., Nomura F., Moss J., Noda M.
    • Journal Title

      Infect Immun.

      Volume: 79 Pages: 617-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), or JNK signaling.2010

    • Author(s)
      Yahiro K., Morinaga N., Moss J., Noda M.
    • Journal Title

      Microb Pathog.

      Volume: 49 Pages: 153-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1alpha or JNK signaling2010

    • Author(s)
      Yahiro, K., N. Morinaga, J. Moss, M. Noda
    • Journal Title

      Microb Pathog

      Volume: 49 Pages: 153-163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] Shiga toxin 2 is specifically released from bacterial cells by two different mechanisms2009

    • Author(s)
      Takeshi Shimizu, Yuko Ohta and Masatoshi Noda
    • Journal Title

      Infect.Immun. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Journal Article] Novel subtilase cytotoxin produced by Shiga-toxigenic Escherichia coil induces apoptosis Vero cells via mitochondrial membrane damage2009

    • Author(s)
      Matsuura G, Morinaga N, Yahiro K, Komine R, Moss J, Yoshida H, Noda M
    • Journal Title

      Infection and Immunity 77

      Pages: 2919-2924

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] Novel subtilase cytotoxin produced by Shiga-toxigenic Escherichia coli induces apoptosis in Vero cells via mitochondrial membrane damage2009

    • Author(s)
      Matsuura, G., N. Morinaga, K. Yahiro, R. Komine, J. Moss, H. Yoshida, M. Noda
    • Journal Title

      Infect Immun

      Volume: 77 Pages: 2919-2924

    • Data Source
      KAKENHI-PROJECT-21390127
  • [Journal Article] A nasal vaccine comprising B-subunit derivative of Shiga toxin 2 for cross-protection aganst Shiga toxin types 1 and 22008

    • Author(s)
      Takao Tsuji, Takeshi Shimizu, Keiko Sasaki, Kentaro Tsukamoto, Hideyuki Arimitsu, Sadayuki Ochi, Toshiyasu Shimizu, Koki Taniguchi, Masatoshi Noda, Paola Neri, Hiroshi Mori
    • Journal Title

      Vaccine 26

      Pages: 2092-2099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Journal Article] Effect of Gb3 in lipid rafts in resistance to Shiga-like toxin of mutant Vero cells2008

    • Author(s)
      Tatsuo Hanashima, Masami Miyake, Kinnosuke Yahiro, Yoshifumi Iwamaru, Akikazu Ando, Naoko Morinaga and Masatoshi Noda
    • Journal Title

      Microb. Pathog. 45

      Pages: 124-133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Journal Article] Subtilase cytotoxin, produced by Shiga-toxigenic Escherichia coli, transiently inhibits protein synthesis of Vero cells via degradation of BiP and induces cell cycle arrest at G1 by downregulation of cyclin D12008

    • Author(s)
      Naoko Morinaga, Kinnosuke Yahiro, Gen Matsuura, Joel Moss and Masatoshi Noda
    • Journal Title

      Cellular Microbiology 10

      Pages: 921-929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Journal Article] Subtilase cytotoxin, produced by Shiga-toxigenic Escherichia coli, transiently inhibits protein synthesis of Vero cells via degradation of BiP and induces cell cycle arrest at GI by downregulation of cyclin Dl2008

    • Author(s)
      Morinaga, N., K. Yahiro, G. Matsuura, J. Moss, and M. Noda
    • Journal Title

      Cell Microbio1 10

      Pages: 921-929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Journal Article] Effect of Gb3 in lipid rafts in resistance to Shiga-like toxin of mutant Vero cells2008

    • Author(s)
      Hanashima, T., M. Miyake, K. Yahiro, Y. Iwamaru, A. Ando, N. Morinaga, and M. Noda
    • Journal Title

      Microb Pathog 45

      Pages: 124-133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Journal Article] Subtilase cytotoxin, produced by Shiga-toxigenic Escherichia coli, transiently inhibits protein synthesis of Vero cells via degradation of BiP, induces cell cycle arrest at G1 by downregulation of cyclin D12008

    • Author(s)
      Morinaga, N., K. Yahiro, G. Matsuura, J. Moss and M. Noda
    • Journal Title

      Cell Microbiol 10

      Pages: 921-929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Journal Article] Effect of Gb3 in lipid rafts in resistance to Shiga-like toxin of mutant Vero cells2008

    • Author(s)
      Hanashima, T., M. Miyake, K. Yahiro, Y. Iwamaru, A. Ando, N. Morinaga and M. Noda
    • Journal Title

      Microb Pathog 45

      Pages: 124-133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Journal Article] Inhibitoly effeots of various plant polyphenols on the toxicity of Staphylococcal alpha-toxin2007

    • Author(s)
      Choi O, Yahiro K, Morinaga N, Miyazaki M, Noda M.
    • Journal Title

      Microb Pathog 42

      Pages: 215-224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Journal Article] Receptor affinity, stability and binding mode of Shiga toxins are determinants of toxicity2007

    • Author(s)
      Takeshi Shimizu, Toshio Sato, Satomi Kawakami, Toshiko Ohta, Masatoshi Noda and Takashi Hamabata
    • Journal Title

      Microb. Pathog. 43

      Pages: 88-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Journal Article] Inhibitory effects of various plant polyphenols on the toxicity of Staphylococcal alpha-toxin2007

    • Author(s)
      Choi O, Yahiro K, Morinaga N, Miyazaki M, Noda M
    • Journal Title

      Microb Pathog 42

      Pages: 215-224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Journal Article] Serine 31 residue of B subunit of Shiga toxin 2 is essential for the secretion in Enterohemorrhagic Escherichia coli2007

    • Author(s)
      Takeshi Shimizu, Satomi Kawakami, Toshio Sato, Terumi Sasaki, Masato Higashide, Takashi Hamabata, Toshiko Ohta and Masatoshi Noda
    • Journal Title

      Infect. Immun. 75

      Pages: 2189-2200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Journal Article] Enhanced poly- (adenosine 5'-diphosphate) -ribosylation of glycoprotein 96 in human colorectal carcinoma2006

    • Author(s)
      Nabeya, Y., Inoue, M., Yahiro, K, Morinaga, N., Sakamoto, A., Noda, M. and Ochiai, T.
    • Journal Title

      Abstract DVD of 20th World Congress of International Society for Digestive Surgery 305

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591456
  • [Journal Article] Characterization of cholix toxin-induced apoptosis in hela cells

    • Author(s)
      Ogura, K., K. Yahiro, H. Tsutsuki, S. Nagasawa, S. Yamasaki, J. Moss, M. Noda
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 37207-37215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Patent] 組換えベクター、該ベクターで形質転換された微生物を利用した一酸化窒素消去を抑制する化合物のスクリーニング方法及び細胞内一酸化窒素濃度の測定方法2016

    • Inventor(s)
      松本明郎、清水 健、野田 公俊
    • Industrial Property Rights Holder
      松本明郎、清水 健、野田 公俊
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-114134
    • Filing Date
      2016-06-08
    • Data Source
      KAKENHI-PROJECT-16K08771
  • [Patent] -酸化窒素を探知するための形質転換用組換えベクター、およびこれを用いた一酸化窒素センサ細胞2011

    • Inventor(s)
      清水健, 津々木博康, 野田公俊
    • Industrial Property Rights Holder
      国立大学法人, 千葉大学
    • Industrial Property Number
      2011-101623
    • Filing Date
      2011-04-28
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Cooperative roles of NO-metabolizing enzymes in enterohemorrhagic Escherichia coli against nitrosative stress2018

    • Author(s)
      Takeshi Shimizu, Akio Matsumoto and Masatoshi Noda
    • Organizer
      52th Joint Conference on Cholera and Other Bacterial Enteric Infections Panel
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08771
  • [Presentation] 腸管出血性大腸菌の菌体内NO濃度を減少させるNO代謝酵素群の協調的な役割2018

    • Author(s)
      清水健、松本明郎、野田公俊
    • Organizer
      第91回 日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-16K08771
  • [Presentation] An evolutionary analysis of a novel virulence gene norV in enterohemorrhagic Escherichia coli O1572018

    • Author(s)
      Takeshi Shimizu, Shinichiro Hirai, Eiji Yokoyama, Kimitoshi Ichimura and Masatoshi Noda
    • Organizer
      The 7th Global Network Forum on Infection and Immunity
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08771
  • [Presentation] in vivo解析による腸管内での志賀毒素産生様式の解明2017

    • Author(s)
      清水健、松本明郎、野田公俊
    • Organizer
      第21回腸管出血性大腸菌感染症研究会
    • Data Source
      KAKENHI-PROJECT-16K08771
  • [Presentation] Role of NO-metabolizing enzymes in enterohemorrahgic Escherichia coli under NO stress conditions2017

    • Author(s)
      Takeshi Shimizu, Akio Matsumoto and Masatoshi Noda
    • Organizer
      日本細菌学会総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Presentation] NOストレス環境における腸管出血性大腸菌のNO代謝酵素の役割2017

    • Author(s)
      清水 健、松本明郎、野田公俊
    • Organizer
      第90回 日本細菌学会総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-16K08771
  • [Presentation] An evolutionary analysis of a novel virulence gene norV that encodes nitric oxide reductase in enterohemorrhagic Escherichia coli O1572016

    • Author(s)
      Takeshi Shimizu, Shinichiro Hirai, Eiji Yokoyama, Kimitoshi Ichimura and Masatoshi Noda
    • Organizer
      50th Joint Conference on Cholera and Other Bacterial Enteric Infections Panel
    • Place of Presentation
      Maryland (USA)
    • Year and Date
      2016-01-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Presentation] 一酸化窒素による腸管出血大腸菌の志賀毒素産生亢進機構の解析2016

    • Author(s)
      市村公敏、清水健、八尋錦之助、竹内裕紀、野田公俊
    • Organizer
      第89回日本細菌学会
    • Place of Presentation
      大阪府大阪市天王寺区
    • Year and Date
      2016-03-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] 腸管出血性大腸菌 O157が保持する新規病原因子一酸化窒素還元酵素遺伝子norVの進化的解析2016

    • Author(s)
      清水健、平井晋一郎、横山栄二、市村公敏、野田公俊
    • Organizer
      第89回日本細菌学会
    • Place of Presentation
      大阪府大阪市天王寺区
    • Year and Date
      2016-03-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] 腸管出血性大腸菌Subtilase cytotoxinによるインフラマーソム抑制機構の解析2016

    • Author(s)
      津々木博康、ThianliZhang,小野勝彦、八尋錦之助、澤智裕、野田公俊
    • Organizer
      第89回日本細菌学会
    • Place of Presentation
      大阪
    • Year and Date
      2016-03-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Shiga-toxigenic Escherichia coli SubAB-induced ER stress causes stress granule formation in mammalian cells2016

    • Author(s)
      Yahiro, K., H. Tsutsuki, K. Ogura, S. Iyoda, K. Ichimura, T. Shimizu, M. Ohnishi, K. Seto, J. Moss, and M. Noda.
    • Organizer
      Bethesda, USA
    • Place of Presentation
      Bethesda, USA
    • Year and Date
      2016-01-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] An evolutionary analysis of a novel virulence gene norV that encodes nitric oxide reductase in enterohemorrhagic Escherichia coli O1572016

    • Author(s)
      Takeshi Shimizu,Shinichiro Hirai,Eiji Yokoyama, Kimitoshi Ichimura ando Masatoshi Noda
    • Organizer
      50th Joint Conference on Cholera and Other Bacterial Enteric Infections Panel
    • Place of Presentation
      Bethesda, USA
    • Year and Date
      2016-01-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] 腸管出血性大腸菌 O157が保持する新規病原因子一酸化窒素還元酵素遺伝子norVの進化的解析2016

    • Author(s)
      清水 健、平井 晋一郎、横山 栄二、市村公敏、野田公俊
    • Organizer
      第89回 日本細菌学会総会
    • Place of Presentation
      大阪国際交流センター(大阪府・大阪市)
    • Year and Date
      2016-03-23
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Presentation] An evolutionary analysis of a novel virulence gene norV in enterohemorrhagic Escherichia coli O1572016

    • Author(s)
      Takeshi Shimizu, Shinichiro Hirai, Eiji Yokoyama, Kimitoshi Ichimura and Masatoshi Noda
    • Organizer
      The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-05-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08771
  • [Presentation] An evolutionary analysis of a novel virulence gene norV that encodes nitric oxide reductase in enterohemorrhagic Escherichia coli O1572015

    • Author(s)
      Takeshi Shimizu, Shinichiro Hirai, Eiji Yokoyama, Kimitoshi Ichimura and Masatoshi Noda
    • Organizer
      The 9th Triennial International Symposium on Shiga Toxin (Verocytotoxin) Producing Escherichia coli infections
    • Place of Presentation
      Boston (USA)
    • Year and Date
      2015-09-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Presentation] 腸管出血性大腸菌 O157が保持する一酸化窒素還元酵素遺伝子の進化的解析2015

    • Author(s)
      清水 健、平井 晋一郎、横山 栄二、市村公敏、野田公俊
    • Organizer
      第19回腸管出血性大腸菌感染症研究会
    • Place of Presentation
      国立医薬品食品衛生研究所(東京都・世田谷区)
    • Year and Date
      2015-07-09
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Presentation] Characterization of Shiga-toxigenic Escherichia coli Sub AB uptake pathway in HeLa cells2014

    • Author(s)
      Sayaka Nagasawa, Kinnosuke Yahiro, Kohei Ogura, Hiroyasu Tsutsuki, Masatoshi Noda
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Inhibition of autophagy by SubAB is regulated by PERK-dependent pathway in Hela cells2014

    • Author(s)
      Kinnosuke Yahiro, Masatoshi Noda
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] The surface sensor NlpE of enterohemorrhagic Escherichia coli contributes to2014

    • Author(s)
      Takeshi Shimizu, Kimitoshi Ichimura and Masatoshi Noda
    • Organizer
      48th US-Japan Cooperative Medical Sciences Program Conference on Cholera and Other Bacterial Enteric Infections
    • Place of Presentation
      Dhaka, Bangladesh
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Helicobacter pylori VacA-induced autophagy and apoptosis are regulated by LRP1.2013

    • Author(s)
      Kinnosuke Yahiro, Masayuki Nakano, Masatoshi Noda, Toshiya Hirayama
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ(千葉)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] 腸管出血性大腸菌の産生するSubAB の PERKを介したアポトーシス制御機構2013

    • Author(s)
      Kinnnosuke Yahiro, Hiroyasu Tsutsuki, Masatoshi Noda
    • Organizer
      第60回毒素シンポジウム
    • Place of Presentation
      兵庫県
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Subtilase cytotoxin induces stress granule formation through PERK dependent pathway2013

    • Author(s)
      Hiroyasu Tsutsuki, Kinnosuke Yahiro, Tohru Shimizu, Masatoshi Noda
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ(千葉)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Role for the surface senssor NlpE of enterohemorrhagic Escherichia coli in adherence to cells.2013

    • Author(s)
      Takeshi Shimizu, Masatoshi Noda
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張メッセ(千葉)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] 腸管出血性大腸菌の産生するSubABのPERKを介したアポトーシス制御機構2012

    • Author(s)
      八尋 錦之助、津々木 博康、小倉康平、野田 公俊
    • Organizer
      第59回トキシンシンポジウム
    • Place of Presentation
      とかちプラザ(北海道)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Inhibitory effect of subtilase cytotoxin on LPS-induced nitric oxide production by macrophages.2012

    • Author(s)
      Hiroyasu Tsutsuki, Kinnosuke Yahiro, Takeshi Shimizu and Masatoshi Noda
    • Organizer
      THE 33rd NAITO CONFERENCE ON Oxygen Biology : Hypoxia, Oxidative Stress and Diseases.
    • Place of Presentation
      シャトレーゼガトーキングダム札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Molecular mechanism of inhibitory effect of SubAB on nitric oxide production by macrophages2012

    • Author(s)
      津々木博康、八尋錦之助、清水健、野田公俊
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎ブリックホール(長崎)(招待講演)
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Fetal hemorrhage in mice induced by Subtilase cytotoxin of Shiga-toxigenic Escherichia coli2012

    • Author(s)
      野田公俊
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Inhibitory effect of SubAB cytotoxin of enterohemorrhagic Escherichia coli on LPS-induced nitric oxide production by macrophages2012

    • Author(s)
      Hiroyasu Tsutsuki and Masatoshi Noda
    • Organizer
      2012 IEIIS in National Center of Sciences Building
    • Place of Presentation
      国立情報学研究所(東京)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] SubAB-induced apoptosis is regulated by a PERK-dependent proteasome pathway in HeLa cells2012

    • Author(s)
      八尋錦之助、津々木博康、小倉康平、永澤明佳、盛永直子、野田公俊
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Diversity in the mechanism of human cell death caused by ADP-ribosyltransferase Cholix toxin2012

    • Author(s)
      小倉康平, 八尋錦之助, 山崎伸二, 野田公俊
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Regulation of Subtilase cytotoxin (SubAB)-induced cell death by a PKR-like endoplasmic reticulum kinase (PERK)-dependent proteasome pathway in HeLa cells2012

    • Author(s)
      Kinnosuke Yahiro, Hiroyasu Tsutsuki, Kohei Ogura, Sayaka Nagasawa, Takeshi Shimizu, Joel Moss, Masatoshi Noda
    • Organizer
      7th US-Japan Cholera and Other Bacterial Enteric Infections Joint Panel Meeting.
    • Place of Presentation
      千葉大学薬学部創立120周年記念講堂(千葉)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] NO biosensor plasmid for investigating2012

    • Author(s)
      清水健, 津々木博康, 野田公俊
    • Organizer
      NO levels within macrophages during bacterial infection
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Subtilase cytotoxin enhances E. coli survival in macrophages by suppression of nitric oxide production through the inhibition of NF-kB activation.2012

    • Author(s)
      Hiroyasu Tsutsuki, Kinnosuke Yahiro, Takeshi Shimizu, Masatoshi Noda
    • Organizer
      47th US Japan Cholera and Other Bacterial Enteric Infections Joint Panel Meeting.
    • Place of Presentation
      千葉大学薬学部創立120周年記念講堂(千葉)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Molecular mechanism of inhibitory effect of2012

    • Author(s)
      津々木博康, 八尋錦之助, 清水健, 野田公俊
    • Organizer
      SubAB on nitric oxide production by macrophages
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Shiga toxin and a novel toxin produced by Shiga-toxigenic Escherichia coli.2012

    • Author(s)
      Masatoshi Noda
    • Organizer
      The 11^<th> Korea-Japan International Symposium on Microbiology
    • Place of Presentation
      韓国
    • Year and Date
      2012-09-14
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] SubAB-induced apoptosis is regulated by a PERK-dependent proteasome pathway in HeLa cells2012

    • Author(s)
      八尋錦之助, 津々木博康, 小倉康平, 永澤明佳, 盛永直子, 野田公俊
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生する志賀毒素以外の毒素2012

    • Author(s)
      八尋錦之助、津々木博康、小倉康平、野田公俊
    • Organizer
      第95回日本細菌学会関東支部総会
    • Place of Presentation
      ホテル日航東京(東京)
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Fetal hemorrhage in mice induced by Subtilase cytotoxin of Shiga-toxigenic Escherichia coli2012

    • Author(s)
      野田公俊
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎ブリックホール(長崎)(招待講演)
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] NO biosensor plasmid for investigating NO levels within macrophages during bacterial infection2012

    • Author(s)
      清水健、津々木博康、野田公俊
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生するSubABのマウスにおける病態発現解析2011

    • Author(s)
      八尋錦之助, 古川健, 寺崎泰弘, 辻厚至, 盛永直子, 野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Apoptotic signaling pathways in HeLa cells induced by Cholix toxin of Vibrio cholerae2011

    • Author(s)
      小倉康平, 八尋錦之助, 山崎伸二, 野田公俊
    • Organizer
      nternational Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      北海道
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] The nitric oxide reductase of enterohemorrhagic Escherichia coli 0157 : H7 increases Shiga toxin 2 production and plays an important role in its infection2011

    • Author(s)
      Takeshi Shiraizu, Hiroyasu Tsutsuki, Akio Matsumoto, Haruaki Nakaya, Masatoshi Noda
    • Organizer
      45^<th> US-Japan Cholera and Other Bacterial Enteric Infections Joint Panel Meeting
    • Place of Presentation
      インド(招待講演)
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Subtilase cytotoxin inhibits the production of nitric oxide from macrophage2011

    • Author(s)
      津々木博康, 八尋錦之助, 清水健, 野田公俊
    • Place of Presentation
      北海道
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] The nitric oxide reductase of Enterohemorrahgicreductase of Enterohemorrahgic2011

    • Author(s)
      清水健, 津々木博康, 野田公俊
    • Organizer
      Escherichia coli plays an important role for the survival within macrophages
    • Place of Presentation
      北海道
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] コレラ菌由来のADP-リボシルトランスフェラーゼ活性を有するCholix toxinが引き起こすアポトーシスシグナル伝達機構の解析2011

    • Author(s)
      小倉康平, 八尋錦之助, 山崎伸二, 野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌NO reductaseは志賀毒素2の産生を増加させる2011

    • Author(s)
      清水健、津々木博康、野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Place of Presentation
      順天堂大学(東京)(招待講演)
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌 NO reductaseは志賀毒素2の産生を増加させる2011

    • Author(s)
      清水健, 津々木博康, 野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] The nitric oxide reductase of Enterohemorrahgic Escherichia coli plays an important role for the survival within macrophages2011

    • Author(s)
      清水健、津々木博康、野田公俊
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生するSubABのマウスにおける病態発現解析2011

    • Author(s)
      八尋錦之助、古川健、寺崎泰弘、辻厚至、盛永直子、野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Place of Presentation
      順天堂大学(東京)(招待講演)
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Characterization of Subtilase cytotoxin-induced apoptotic signaling pathway in HeLa cells2011

    • Author(s)
      八尋錦之助, 盛永直子, 野田公俊
    • Organizer
      International Union of Microbiological Societies
    • Place of Presentation
      北海道
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生するSubtilase cytotoxin (SubAB)の細胞内侵入機序の解析2011

    • Author(s)
      永澤明佳、八尋錦之助、茂谷久子、岩瀬博太郎。野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Place of Presentation
      順天堂大学(東京)(招待講演)
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生する新規SubABトキシンによるNO産生抑制機構の解明2011

    • Author(s)
      津々木博康, 八尋錦之助, 清水健, 野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Characterization of Subtilase cytotoxin-induced apoptotic signaling pathway in HeLa cells2011

    • Author(s)
      八尋錦之助、盛永直子、野田公俊
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(北海道)(招待講演)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生する新規SubABトキシンによるNO産生抑制機構の解明2011

    • Author(s)
      津々木博康、八尋錦之助、清水健、野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Place of Presentation
      順天堂大学(東京)(招待講演)
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Subtilase cytotoxin inhibits the production of nitric oxide from macrophage2011

    • Author(s)
      津々木博康、八尋錦之助、清水健、野田公俊
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Subtilase cytotoxin produced by Escherichia coli induces fatal hemorrhage in mice2011

    • Author(s)
      八尋錦之助、古川健、寺崎泰弘、辻厚至、清水健、盛永直子、野田公俊
    • Organizer
      46^<th> US-Japan Cholera and Other Bacterial Enteric Infections Joint Panel Meeting
    • Place of Presentation
      インド
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌が産生するSubtilase cytotoxinはマクロファージのNO産生を抑制する2011

    • Author(s)
      津々木博康, 八尋錦之助, 清水健, 野田公俊
    • Organizer
      第96回日本細菌学会関東支部総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生するSubtilase cytotoxin(SubAB)の細胞内侵入機序の解析2011

    • Author(s)
      永澤明佳, 八尋錦之助, 茂谷久子, 岩瀬博太郎, 野田公俊
    • Organizer
      第58回トキシンシンポジウム
    • Place of Presentation
      順天堂大学(東京)
    • Year and Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生する新規SubABトキシンによるNO産生抑制機構の解明2010

    • Author(s)
      津々木博康, 八尋錦之助, 清水健, 野田公俊
    • Organizer
      インターラボセミナー
    • Place of Presentation
      千葉
    • Year and Date
      2010-12-11
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Subtilase cytotoxin induces activation of Bax/Bak, leading to cytochromec release and apoptosis2010

    • Author(s)
      盛永直子、八尋錦之助、野田公俊
    • Organizer
      日本細菌学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-03-28
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Subtilase cytotoxin induces activation of Bax/Bak, leading to cytochrome c release and apoptosis2010

    • Author(s)
      盛永直子, 八尋錦之助, 野田公俊
    • Organizer
      第83回日本細菌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Adherence of EHEC to Caco-2 cells induces the increase of Stx1 production2010

    • Author(s)
      清水健, 野田公俊
    • Organizer
      第83回日本細菌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] コレラ菌由来の新規外毒素が示す標的細胞致死活性2010

    • Author(s)
      小倉康平, 八尋錦之助, 野田公俊
    • Organizer
      インターラボセミナー
    • Place of Presentation
      千葉
    • Year and Date
      2010-12-11
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Identification of Subtilase cytotoxin receptors in HeLa cells2010

    • Author(s)
      八尋錦之助, 盛永直子, 野田公俊
    • Organizer
      第83回日本細菌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管出血性大腸菌の産生する Subtilase cytotoxin (SubAB)の毒性発現機序の解析2010

    • Author(s)
      八尋錦之助, 盛永直子, 野田公俊
    • Organizer
      第57回トキシンシンポジウム
    • Place of Presentation
      滋賀
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] 腸管Hi.血性大腸菌の産生するSubtilase cytotoxin(SubAB:)の毒性発現機序の解析2010

    • Author(s)
      八尋錦之助、盛永直子、野田公俊
    • Organizer
      第57回トキシンシンポジウム
    • Place of Presentation
      滋賀県
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Identification of SubAB receptor and its signaling pathway associated with BiP cleavage leading to apoptosis2010

    • Author(s)
      八尋錦之助, 盛永直子, 野田公俊
    • Organizer
      45th US-Japan Cholera and Other Baceterial Enteric Infections Joint Panel Meeting
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] Effect of phage-inducing agent on the number of Stx2-expressed cells in Shiga toxin-producing Escherichia coli2009

    • Author(s)
      清水健, 野田公俊
    • Organizer
      44th US-Japan Cholera and Other Bacterial Enteric Infections Joint Panel Meeting
    • Place of Presentation
      サンディエゴ、USA
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] STECの産生するsubtilase cytotoxinによるVero細胞蛋白合成阻害機構と細胞周期への影響2009

    • Author(s)
      盛永直子・八尋錦之助・松浦玄・野田公俊
    • Organizer
      日本細菌学会
    • Place of Presentation
      愛知県(名古屋国際会議場)
    • Year and Date
      2009-03-12
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] 腸管出血性大腸菌には志賀毒素2に対する2種類の特異的な放出機構がある2009

    • Author(s)
      清水健、野田公俊
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      名古屋、名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Presentation] Subtilase cytotoxin induces apoptosis in HeLa cells via mitochorndrial membrane damage2009

    • Author(s)
      Yahiro, K., Morinaga, N., Noda, M
    • Organizer
      Cholera and other bacterial enteric infections
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2009-10-13
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] プロテオーム解析による細菌毒素宿主受容体の同定と性状解析2009

    • Author(s)
      八尋錦之助, 盛永直子, 野田公俊
    • Organizer
      第6回千葉疾患プロテオミクス研究会
    • Place of Presentation
      千葉県
    • Year and Date
      2009-12-06
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] STECの産生するsubtilase cytotoxin によるVero細胞蛋白合成阻害機構と細胞周期への影響2009

    • Author(s)
      盛永直子・八尋錦之助・松浦玄・野田公俊
    • Organizer
      日本細菌学会
    • Place of Presentation
      愛知県(名古屋国際会議場)
    • Year and Date
      2009-03-12
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] ubtilase cytotoxin induced apoptosis in HeLa cells via mitochondrial membrane damage2009

    • Author(s)
      八尋錦之助, 盛永直子, 野田公俊
    • Organizer
      44th US-Japan Cholera and Other Bacterial Enteric Infections Joint Panel Meeting
    • Place of Presentation
      サンディエゴ、USA
    • Data Source
      KAKENHI-PROJECT-21390127
  • [Presentation] STECの産生するsubtilase cytotoxin (SubAB)によるVero細胞のG1アレスト誘導機構2008

    • Author(s)
      盛永直子・八尋錦之助・野田公俊
    • Organizer
      毒素シンポジウム
    • Place of Presentation
      山梨県(ラフォーレ山中湖)
    • Year and Date
      2008-07-03
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] Subtilase cytotoxin induced Gl arrest of Vero cells through degradation of cyclon Dl2008

    • Author(s)
      Naoko Moringa, Kinnosuke Yahiro, Joel Moss, Masatoshi Noda
    • Organizer
      Cholera and other bacterial enteric infections
    • Place of Presentation
      福岡県(九州大学医学部百年講堂)
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] 志賀毒素2の分泌にはBサブユニットの特定のアミノ酸残基の側鎖が重要である2008

    • Author(s)
      清水健、佐藤壽男、濱端崇、野田公俊
    • Organizer
      第81回日本細菌学会総会
    • Place of Presentation
      京都、国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Presentation] Subtilase cytotoxin induced G1 arrest of Vero cells through degradation of cyclon D12008

    • Author(s)
      Naoko Moringa, Kinnosuke Yahiro, Joel Moss, Masatoshi Noda
    • Organizer
      Cholera, other bacterial entericinfections
    • Place of Presentation
      福岡県(九州大学医学部百年講堂)
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] A mechanism of Stx2 release from enterohemorrahgic Escherichia coli by a non-secretion system2008

    • Author(s)
      Takeshi Shimizu, Yuko Ohta and Masatoshi Noda
    • Organizer
      43^<rd> Joint Conference on Cholera and Other Bacterial Enteric Infections Panel
    • Place of Presentation
      Centennial Hall in Kyushu University, Fukuoka
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Presentation] STECの産生するsubtilase cytotoxin(SubAB) によるVero細胞のG1 アレスト誘導機構2008

    • Author(s)
      盛永直子・八尋錦之助・野田公俊
    • Organizer
      毒素シンポジウム
    • Place of Presentation
      山梨県(ラフォーレ山中湖)
    • Year and Date
      2008-07-03
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] Binding mode of chimera Shiga toxins and their toxicity2007

    • Author(s)
      Takeshi Shimizu, Toshio Sato, Takashi Hamabata and Masatoshi Noda
    • Organizer
      42^<nd> Joint Conference on Cholera and Other Bacterial Enteric Infections Panel
    • Place of Presentation
      Austin, Texas
    • Data Source
      KAKENHI-PROJECT-19590440
  • [Presentation] STECの産生する新規AB5サブユニット毒素SubAbのBiP分解活性2007

    • Author(s)
      盛永直子・八尋錦之助・松浦玄・野田公俊
    • Organizer
      日本細菌学会
    • Place of Presentation
      大阪府(アジア太平洋トレードセンター)
    • Year and Date
      2007-03-26
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] STECの産生する新規ABサブユニット毒素の性状2007

    • Author(s)
      盛永 直子, 八尋 錦之助, 松浦 玄, 野田 公俊
    • Organizer
      毒素シンポジウム
    • Place of Presentation
      山梨県(八ケ岳ロイヤルホテル)
    • Year and Date
      2007-07-06
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] STECの産生する新規ABサブユニット毒素の性状2007

    • Author(s)
      盛永直子・八尋錦之助・松浦玄・野田公俊
    • Organizer
      毒素シンポジウム
    • Place of Presentation
      山梨県(八ヶ岳ロイヤルホテル)
    • Year and Date
      2007-07-06
    • Data Source
      KAKENHI-PROJECT-19390124
  • [Presentation] Identification of a protein which can receive poly-(adenosine 5'-diphosphate)-ribosylation in human colorectal carcinoma2006

    • Author(s)
      Inoue, M., Nabeya, Y., Yahiro, K, Akai, T., Miyazaki, S., Sakamoto, A., Noda, M. and Ochiai, T.
    • Organizer
      68th Annual Meeting of Japan Surgical Association
    • Place of Presentation
      Hiroshima
    • Year and Date
      2006-11-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591456
  • [Presentation] Enhanced poly-(adenosine 5'-diphosphate)-ribosylation of glycoprotein 96 in human colorectal carcinoma2006

    • Author(s)
      Nabeya, Y., Inoue, M., Yahiro, K., Morinaga, N., Sakamoto, A., Noda, M. and Ochiai, T.
    • Organizer
      20th World Congress of International Society for Digestive Surgery
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2006-11-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591456
  • [Presentation] 腸管出血性大腸菌の産生するSubAB の細胞障害機構の解明

    • Author(s)
      八尋 錦之助、野田 公俊
    • Organizer
      第61回トキシンシンポジウム
    • Place of Presentation
      ルネッサンスリゾートナルト(徳島県・鳴門市)
    • Year and Date
      2014-09-03 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] 腸管出血性大腸菌の接着を認識する病原因子発現機構の解析

    • Author(s)
      清水 健、市村公敏、野田公俊
    • Organizer
      第18回腸管出血性大腸菌感染症研究会
    • Place of Presentation
      同志社大学室町キャンパス、京都府、京都市
    • Year and Date
      2014-07-15 – 2014-07-16
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Presentation] 腸管出血性大腸菌の産生するSubtilase cytotoxin (SubAB)は アクチン及び脂質ラフト依存的に細胞内に取り込まれる」(若手奨励賞受賞)

    • Author(s)
      永澤明佳、小倉康平、津木博康、岩瀬博太郎、野田公俊、八尋錦之助
    • Organizer
      第61回トキシンシンポジウム
    • Place of Presentation
      ルネッサンスリゾートナルト(徳島県・鳴門市)
    • Year and Date
      2014-09-03 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] The surface sensor NlpE of enterohemorrhagic Escherichia coli contributes to the regulation of virulence factors via adherence of bacteria to Caco-2 cells

    • Author(s)
      Takeshi Shimizu, Kimitoshi Ichimura and Masatoshi Noda
    • Organizer
      49th Joint Conference on Cholera and Other Bacterial Enteric Infections Panel
    • Place of Presentation
      Gainesville, Florida, USA
    • Year and Date
      2015-01-14 – 2015-01-16
    • Data Source
      KAKENHI-PROJECT-26670208
  • [Presentation] 腸管出血性大腸菌の産生するSubtilase cytotoxin の細胞侵入機構の解析

    • Author(s)
      永澤明佳,八尋錦之助,齋藤久子 ,岩瀬博太郎,野田公俊
    • Organizer
      第 97 回日本細菌学会関東支部総会
    • Place of Presentation
      東京ドームホテル(東京都・文京区)
    • Year and Date
      2014-10-30 – 2014-10-31
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] 病原細菌のAB5型トキシンの作用機構等に関する研究

    • Author(s)
      Masatoshi Noda
    • Organizer
      第23回学会賞受賞者特別講演会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] Shiga-toxigenic Escherichia coli produced SubAB enters via lipid-raft- and an actin-dependent endocytosis in HeLa cells.

    • Author(s)
      八尋錦之助、永澤明佳,齋藤久子 ,岩瀬博太郎,野田公俊
    • Organizer
      49th U.S.-Japan Conference on Cholera and Other Enteric Bacterial Infections
    • Place of Presentation
      フロリダ(米国)
    • Year and Date
      2015-01-14 – 2015-01-16
    • Data Source
      KAKENHI-PROJECT-24390104
  • [Presentation] 腸管出血性大腸菌のsurface sensor NlpEは接着時にCpx経路によって病原因子の発現を調節する

    • Author(s)
      清水 健、市村公敏、野田公俊
    • Organizer
      第88回 日本細菌学会総会
    • Place of Presentation
      長良川国際会議場、岐阜県、岐阜市
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26670208
  • 1.  MORINAGA Naoko (20092108)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 40 results
  • 2.  SHIMIZU Takeshi (70312840)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 57 results
  • 3.  MIYAKE Masami (10251175)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  KUWABARA Satoshi (70282481)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 3 results
  • 5.  YAHIRO Kinnosuke (80345024)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 64 results
  • 6.  MORI Masahiro (70345023)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 16 results
  • 7.  HONDA Takesh (60029808)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  NOMURA Fumio (80164739)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  KATO Iwao (40012702)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  SHINODA Sumio (50029782)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  MITUYAMA Masao (10117260)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  TSUTSUKI Hiroyasu (40586608)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 36 results
  • 13.  NAKAI Toshiaki (30049192)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  ISOBE Kazumasa (10151440)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  丹沢 秀樹 (50236775)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  中村 信一 (90019620)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  NAKAZAWA Teruko (40053053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MIZUGUCHI Yasuo (10072919)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SAKURAI Jun (80029800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKANO Masayasu (70048958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TAKEDA Yoshifumi (30029772)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YOKOCHI Takashi (20126915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  HIRAYAMA Toshiya (50050696)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  WADA Akihiro (70253698)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HATTORI Takamichi (30114317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SEKI Hiroko (60114245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  NABEYA Yoshihiro (40322028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 28.  KAMIO Yoshiyuki (00109175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  佐藤 研一 (40009139)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  笹川 千尋 (70114494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  渡辺 俊英 (10301095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  小倉 康平 (00586612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 33.  濱端 崇 (40311427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  玉山 詩技子 (50241964)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  木下 タロウ (10153165)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  落合 武徳 (80114255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 37.  畝本 力 (30089601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  MOSS Joel
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  SUTO Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  SUZUKI Kotaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  MATSUMOTO Ayako
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  MATSUMOTO Akio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  伊豫田 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  中島 裕史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  中谷 晴昭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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