Akito TOMOMURA 友村明人

… Alternative Names

友村明人トモムラアキト

TOMOMURA Akito 友村明人

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Researcher Number	60188810
Other IDs
External Links
Affiliation (Current)	2025: 明海大学, 歯学部, 名誉教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 明海大学, 歯学部, 名誉教授 2018 – 2020: 明海大学, 歯学部, 教授 2012 – 2016: 明海大学, 歯学部, 教授 2003 – 2006: Meikai University School of Dentistry, Biochemistry, Professor, 歯学部, 教授 1999 – 2002: 明海大学, 歯学部, 助教授 … More 1996 – 1998: 明海大学, 歯学部, 講師 1990: Kagoshima University Dental School, 歯学部附属病院, 助手 1986: Kagoshima University, School of Dentistry, 歯学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry Except Principal Investigator Orthodontic/Pediatric dentistry / Basic Section 59040:Nutrition science and health science-related / Basic Section 57020:Oral pathobiological science-related / Basic Section 57010:Oral biological science-related / Functional basic dentistry / 外科・放射線系歯学 / Functional basic dentistry / Periodontology / Surgical dentistry
Keywords	Principal Investigator プロテアーゼ / カルシウム / 骨吸収 / protease / calcium / 破骨細胞 / bone resorption / 骨代謝 / alzheimer / アルルハイマー … More / 神経 / 骨 / アルツハイマー / gene therapy / ovariectomized mouse / osteoporosis / gene expression / osteoclast / 遺伝子治療 / 卵巣摘出マウス / 骨粗鬆症 / 遺伝子発現 / 骨呼吸 / Receptor / Protease / Bone resorption / Osteoclast / レセプター / ラフト / 分化 … More Except Principal Investigator 骨粗鬆症 / 骨芽細胞 / 骨吸収 / 炎症 / 骨形成 / 破骨細胞 / ゲラニルゲラニオール / プロテアーゼ / カルデクリン / ミクログリア細胞 / アルツハイマー病 / ミクログリア / 神経変性 / exosome / macrophage / CXCL10 / 口腔がん細胞 / CXCL11 / LPS / マクロファージ / sTREM2 / TREM2 / 骨代謝疾患 / 卵巣摘出マウス / リウマチ / 糖尿病 / 核内受容体 / ゲラ二ルゲラニオール / 関節リウマチ / ビスホスホネート / 歯髄細胞 / Dental Disease / Malocclusion / Jaw Growth / Dietary Behavior / Australian Aborigine / Australian white / 歯科疾患 / 不正咬合 / 顎発育 / 食生態 / オ-ストラリア・アボリジン / オ-ストラリア白人 / Flow cytometry / Cell cycle / Radiation effect / Tooth germ cell / 【G_2】ブロック / フローサイトメトリー / 細胞周期 / 放射線効果 / 歯胚組織細胞 / Bone / Calcium / Protease / Orthodontics / 遺伝子治療 / 血清カルシウム降下因子 / 骨代謝 / 骨 / カルシウム / 歯科矯正 / Osteoblast / Hepatocyte / Parathyroid hormone / Bone resorption / Hepatocyte growth factor / Serum concentration / Fetuin / Rat / 副甲状腺ホルモン / カテプシンL / ラットフェチュイン / α2-HS糖タンパク / 肝細胞 / 甲状腺ホルモン / 肝細胞増殖因子 / 血清濃度 / フェチュイン / ラット / 間葉系幹細胞 / 再生療法 / 不織布フィルター / 顎骨 / 間葉系細胞 / イオンチャンネル / TRPV / 歯の移動 / 実験モデル / 疼痛 / 矯正歯科治療 / 炎症性骨吸収 Less

ゲノム編集を利用した膜結合型および遊離型TREM2の骨免疫学的機能の解析
- Principal Investigator
  
  坂東健二郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Meikai University
多能性プロテアーゼのアルツハイマー病におけるミクログリア極性転換調節機構の解析
- Principal Investigator
  
  友村美根子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Josai University
  Meikai University
Efficacy of geranylgeraniol, which inhibits bone resorption and promotes bone formation, in metabolic bone diseases
- Principal Investigator
  
  Tomomura Mineko
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Josai University
  Meikai University
Elucidation of the action of geranylgeraniol which reciprocally controls bone resorption and bone formation and its application to osteoporosis
- Principal Investigator
  
  TOMOMURA mineko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Development of regeneration therapy by mesenchymal stem cell from gnathic bone marrow using novel nonwoven fabric filter
- Principal Investigator
  
  Hayashi Joichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontology
- Research Institution
  Meikai University
Inhibitory mechanism of caldecrin on RANKL-stimulated signaling platform formation in the osteoclastsPrincipal Investigator
- Principal Investigator
  
  TOMOMURA Akito
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Analysis of molecular mechanism of caldecrin on osteoclastic bone resorption by inflammatory cytokine
- Principal Investigator
  
  TAMURA Nobuaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Meikai University
Epochal approach triggered to acid-sensitive ion-channel to regulate pain during tooth movement
- Principal Investigator
  
  SUDA Naoto
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Meikai University
Searches for the molecular pathogenesis of skeretal and neuronal system from serum calcium-decreasing factor, caldecrin, knock out mousePrincipal Investigator
- Principal Investigator
  
  TOMOMURA Akito
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Fundamental examination of orthodontic treatment using serum calcium-decreasing factor, caldecrin
- Principal Investigator
  
  KIYOMURA Masaru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Meikai University
Gene therapy with serum calcium-decreasing factor, caldecrin, for osteoporosisPrincipal Investigator
- Principal Investigator
  
  TOMOMURA Akito
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University School of Dentistry
Exploration of genes and the functions affected by serum calcium-decreasing factor (caldecrin)Principal Investigator
- Principal Investigator
  
  TOMOMURA Akito
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Analysis of Receptor for Bone Resorption Suppressor CaldecrinPrincipal Investigator
- Principal Investigator
  
  TOMOMURA Akito
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Physiological roles of rat fetuin on bone metabolism
- Principal Investigator
  
  DAIKUHARA Yasushi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kagoshima University
Transfiguration of Diet and Reduction of Jaw Development in Australian White and Aborigine
- Principal Investigator
  
  ITO Gakuji
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagoshima University
Effects of X Irradiation on Cell Kinetics in Cultured Rat Tooth Germ Cells.
- Principal Investigator
  
  NOIKURA Takenori
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  外科・放射線系歯学
- Research Institution
  Kagoshima University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 Other

All Journal Article Presentation Book

[Book] Purification and Biological Function of Caldecrin, Research Topics in Medicines and How Our Board Members Are Engaged in Them (ed., Hiroshi Sakagami) pp1-172022
- Author(s)
  Tomomura A, Bandow K, Tomomura M.
- Total Pages
  17
- Publisher
  MDPI
- ISBN
  9783036536859
- Data Source
  KAKENHI-PROJECT-22K11708
[Journal Article] Isolation of Pro-Osteogenic Compounds from Euptelea polyandra That Reciprocally Regulate Osteoblast and Osteoclast Differentiation2023
- Author(s)
  Suzuki R, Shirataki Y, Tomomura A, Bandow K, Sakagami H, Tomomura M
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 12 Issue: 24 Pages: 17479-17479
- DOI
  10.3390/ijms242417479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10060
[Journal Article] Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE12021
- Author(s)
  Komaki Keisuke、Takano Tetsuya、Sato Yutaka、Asada Akiko、Ikeda Shikito、Yamada Kaoru、Wei Ran、Huo Anni、Fukuchi Aoi、Saito Taro、Ando Kanae、Murayama Shigeo、Araki Wataru、Kametani Fuyuki、Hasegawa Masato、Iwatsubo Takeshi、Tomomura Mineko、Fukuda Mitsunori、Hisanaga Shin-ichi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 6 Pages: 729-738
- DOI
  10.1093/jb/mvab094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07836, KAKENHI-PROJECT-19K06942, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-22K07550, KAKENHI-PROJECT-22K11708, KAKENHI-PROJECT-19K07988, KAKENHI-PROJECT-22H04923
[Journal Article] Purification and Biological Function of Caldecrin2021
- Author(s)
  Tomomura Akito、Bandow Kenjiro、Tomomura Mineko
- Journal Title
  
  Medicines
  
  Volume: 8 Issue: 8 Pages: 41-41
- DOI
  10.3390/medicines8080041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10075, KAKENHI-PROJECT-19K10060
[Journal Article] Caldecrin inhibits lipopolysaccharide-induced pro-inflammatory cytokines and M1 macrophage polarization through the immunoreceptor triggering receptor expressed in myeloid cells-22020
- Author(s)
  Bandow Kenjiro、Hasegawa Hiroya、Tomomura Mineko、Tomomura Akito
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 523 Issue: 4 Pages: 1027-1033
- DOI
  10.1016/j.bbrc.2020.01.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10075, KAKENHI-PROJECT-19K10060
[Journal Article] Further Quantitative Structure-Cytotoxicity Relationship Analysis of 3-Styrylchromones.2020
- Author(s)
  Takao K, Hoshi K, Sakagami H, Shi H, Bandow K, Nagai J, Uesawa Y, Tomomura A, Tomomura M, Sugita Y.
- Journal Title
  
  Anticancer Res.
  
  Volume: 40 Issue: 1 Pages: 87-95
- DOI
  10.21873/anticanres.13929
- NAID
  120006845507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10060
[Journal Article] Augmentation of Neurotoxicity of Anticancer Drugs by X-Ray Irradiatio2020
- Author(s)
  Nakaya G, Sakagami H, Koga-Ogawa Y, Shiroto A, NobesawaT, Ueda D, Nakatani S, Kobata K, Iijima Y, Tone S, Debit-Gonzaleza, Garcia-Contreras R, Tomomura M, Kito S, Tamura N , Takeshima H
- Journal Title
  
  in vivo
  
  Volume: 34 Issue: 3 Pages: 1009-1016
- DOI
  10.21873/invivo.11869
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10060, KAKENHI-PROJECT-20K16736
[Journal Article] Quantitative Structure-Cytotoxicity Relationship of 2-(N-cyclicamino)chromone Derivatives2018
- Author(s)
  SHI HAIXIA、NAGAI JUNKO、SAKATSUME TSUKASA、BANDOW KENJIRO、OKUDAIRA NORIYUKI、SAKAGAMI HIROSHI、TOMOMURA MINEKO、TOMOMURA AKITO、UESAWA YOSHIHIRO、TAKAO KOICHI、SUGITA YOSHIAKI
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 7 Pages: 3897-3906
- DOI
  10.21873/anticanres.12674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519
[Journal Article] Dental Application of Natural Products2018
- Author(s)
  Sakagami Hiroshi、Tomomura Mineko
- Journal Title
  
  Medicines
  
  Volume: 5 Issue: 1 Pages: 21-21
- DOI
  10.3390/medicines5010021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519
[Journal Article] Quantitative Structure-Cytotoxicity Relationship of Pyrano[4,3-b]chromones2018
- Author(s)
  NAGAI JUNKO、SHI HAIXIA、KUBOTA YUKA、BANDOW KENJIRO、OKUDAIRA NORIYUKI、UESAWA YOSHIHIRO、SAKAGAMI HIROSHI、TOMOMURA MINEKO、TOMOMURA AKITO、TAKAO KOICHI、SUGITA YOSHIAKI
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 8 Pages: 4449-4457
- DOI
  10.21873/anticanres.12747
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519
[Journal Article] Search of Neuroprotective Polyphenols Using the “Overlay” Isolation Method2018
- Author(s)
  Sakagami Hiroshi、Shi Haixia、Bandow Kenjiro、Tomomura Mineko、Tomomura Akito、Horiuchi Misaki、Fujisawa Tomohiro、Oizumi Takaaki
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 8 Pages: 1840-1840
- DOI
  10.3390/molecules23081840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11487
[Journal Article] Protection of differentiating neuronal cells from amyloid β peptide-induced injury by alkaline extract of leaves of Sasa senanensis Rehder.2018
- Author(s)
  Sakagami H, Tsuji M,Tomomura M, Masuda Y, Iwama S, Nakagawa M, Suzuki H, Tanaka K, Abe T,Tamura N, Tomomura A, Yokose S, Takeshima H, Natori T,Horiuchi M, Fujisawa T, Kiuchi Y, Oguchi K, Yasui Y, Oizumi H and Oizumi T.
- Journal Title
  
  In Vivo
  
  Volume: 32 Issue: 2 Pages: 231-239
- DOI
  10.21873/invivo.11229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-17K12055
[Journal Article] Screening for natural medicines effective for the treatment of osteoporosis2018
- Author(s)
  Suzuki Ryuichiro、Fukami Satoshi、Tomomura Mineko、Tomomura Akito、Shirataki Yoshiaki
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 73 Issue: 1 Pages: 331-337
- DOI
  10.1007/s11418-018-1258-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11487
[Journal Article] Quantitative Structure-Cytotoxicity Relationship of 3-(N-Cyclicamino)chromone Derivatives2018
- Author(s)
  SHI HAIXIA、NAGAI JUNKO、SAKATSUME TSUKASA、BANDOW KENJIRO、OKUDAIRA NORIYUKI、UESAWA YOSHIHIRO、SAKAGAMI HIROSHI、TOMOMURA MINEKO、TOMOMURA AKITO、TAKAO KOICHI、SUGITA YOSHIAKI
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 8 Pages: 4459-4467
- DOI
  10.21873/anticanres.12748
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519
[Journal Article] ＬＰＳ誘導性破骨細胞分化に対するカルデクリンの効果2018
- Author(s)
  川口祥子、坂東健二郎、田村暢章、友村美根子、嶋田淳、友村明人
- Journal Title
  
  明海歯科医学
  
  Volume: 47 Pages: 126-138
- NAID
  40021698104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11487
[Journal Article] クマザサ葉抽出液は骨芽細胞と破骨細胞を相反的に制御することで骨形成を促進する2017
- Author(s)
  友村美根子、友村明人、大泉　高明、　安井　利一、坂上宏
- Journal Title
  
  New Food Industry
  
  Volume: 59 Pages: 41-45
- NAID
  40021375165
- Data Source
  KAKENHI-PROJECT-16K11487
[Journal Article] Evaluation of Biological Activity of Mastic Extracts Based on Chemotherapeutic Indices.2017
- Author(s)
  Suzuki R, Sakagami H, Amano S, Fukuchi K, Sunaga K, Kanamoto T, Terakubo S, Nakashima H, Shirataki Y, Tomomura M, Masuda Y, Yokose S, Tomomura A, Watanabe H, Okawara M, and Matahira Y.
- Journal Title
  
  In Vivo
  
  Volume: 31 Issue: 4 Pages: 591-598
- DOI
  10.21873/invivo.11099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-15K01319
[Journal Article] Extract of Sasa senanensis Rehder Leaf promotes osteoblast differentiation in MC3T3-E1 Cells.2017
- Author(s)
  Tomomura M, Tomomura A, Oizumi T, Yasui T and Sakagami H.
- Journal Title
  
  J Meikai Dent Med
  
  Volume: 46 Pages: 111-116
- NAID
  40021358973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11487
[Journal Article] Quantitative Structure-Cytotoxicity Relationship of Chalcones2017
- Author(s)
  Sakagami H, Masuda Y,Tomomura M,Yokose S, Uesawa Y,Ikezoe N, Asahara D, Takao K, Kanamoto T, Terakubo S, Kagaya H, Nakashima H,and Sugita T.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Issue: 3 Pages: 1091-1098
- DOI
  10.21873/anticanres.11421
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519
[Journal Article] マスティック抽出画分の薬理作用2017
- Author(s)
  坂上宏、天野　滋、増田宜子、横瀬敏志、友村美根子、友村明人、鈴木　龍一郎、須永克佳、白瀧義明、福地邦彦、　金本大成、寺久保繁美、中島秀喜、渡邉博文、大川原正喜、又平芳春
- Journal Title
  
  New Food Industry
  
  Volume: 59 Pages: 67-76
- NAID
  40021313649
- Data Source
  KAKENHI-PROJECT-16K11487
[Journal Article] Quantitative structure-cytotoxicity relationship of newly synthesized piperic acid esters.2017
- Author(s)
  Sakagami H, Uesawa Y, Masuda Y, Tomomura M, Yokose S, Miyashiro T, Murai J, Takao K, Kanamoto T, Terakubo S, Kagaya H, Nakashima H, and Sugita Y.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Issue: 11 Pages: 6161-6168
- DOI
  10.21873/anticanres.12065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519, KAKENHI-PROJECT-15K01319, KAKENHI-PROJECT-15K08111
[Journal Article] 骨粗鬆症　ゲラニルゲラニオールと骨代謝2017
- Author(s)
  友村美根子
- Journal Title
  
  Medical Science Digest
  
  Volume: 43 Pages: 10-12
- Data Source
  KAKENHI-PROJECT-16K11487
[Journal Article] The kinase activity of endosomal kinase LMTK1A regulates its cellular localization and interactions with cytoskeletons.2016
- Author(s)
  Sharma S, Tsutsumi K, Saito T, Asada A, Ando K, Tomomura T, Hisanaga S.
- Journal Title
  
  Genes Cells.
  
  Volume: 21 Issue: 10 Pages: 1080-1094
- DOI
  10.1111/gtc.12404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16K07060, KAKENHI-PROJECT-16K11487
[Journal Article] 不織布フィルターを用いた閉鎖系デバイスによる顎骨骨髄からの間葉系幹細胞分離に関する研究2015
- Author(s)
  林　丈一朗，友村　明人，申　基喆，辰巳順一，谷田部　一大，大西　英知
- Journal Title
  
  明海歯科医学
  
  Volume: 44 Pages: 17-26
- NAID
  40020368133
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670894
[Journal Article] New biological activities of Rhinacanthins from the root of Rhinacanthus nasutus.2013
- Author(s)
  Horii H, Suzuki R, Sakagami H, Tomomura M, Tomomura A, Shirataki Y.
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 453-459
- NAID
  120005520782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592811
[Journal Article] Serum calcium-decreasing factor, caldecrin, inhibits receptor activator of NF-κB ligand (RANKL)-mediated Ca2+ signaling and actin ring formation in mature osteoclasts via suppression of Src signaling pathway2012
- Author(s)
  Tomomura M, Hasegawa H, Suda N, Sakagami H, Tomomura A
- Journal Title
  
  J Biol Chem
  
  Volume: 287(22) Issue: 22 Pages: 17963-74
- DOI
  10.1074/jbc.m112.358796
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593018, KAKENHI-PROJECT-24592811, KAKENHI-PROJECT-24659916
[Presentation] ヒト口腔扁平上皮がん細胞に対する抗がん剤および過酸化水素とマイルドハイパーサーミアの併用効果.2021
- Author(s)
  田川裕也、坂上宏、天野滋、友村美根子、坂東健二郎、高尾浩一、杉田義昭、植沢芳広、山本信治、坂下英明、中鍛治里奈、小泉敏之、光藤健司、藤内祝
- Organizer
  第38回日本ハイパーサーミア学会
- Data Source
  KAKENHI-PROJECT-19K10060
[Presentation] 新規3-スチルクロモン誘導体のヒト口腔扁平上皮癌細胞に対する構造-選択毒性相関2020
- Author(s)
  坂上　宏、史海霞, 植沢芳広、永井純、、友村明人、坂東健二郎、友村美根子、星　かおり、高尾浩一、杉田義昭
- Organizer
  第93回日本薬理学会（横浜）
- Data Source
  KAKENHI-PROJECT-19K10060
[Presentation] ゲラニルゲラニオールは骨粗鬆症の進行を抑える。2019
- Author(s)
  友村美根子、坂東健次郎、鈴木龍一郎、坂上宏、友村明人
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K10060
[Presentation] 分化した神経細胞の簡易調製法（オーバーレイ法）の開発：ポリフェノール類の神経保護作用とホルメシス効果2018
- Author(s)
  堀内美咲、史海霞、坂上宏、坂東健二郎、友村美根子、友村明人、藤澤知弘、勝呂まどか、大泉浩史、大泉高明
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] Serum Calcium-Decreasing Factor, Caldecrin, Protects Against Amyloid-β Toxicity Through Proteolytic Cleavage.2018
- Author(s)
  Tomomura Mineko, Tomomura Akito,　Kamiguchi Hiroyuki
- Organizer
  第41回日本神経科学
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] ピラノ[4,3-b]クロモン誘導体の定量的構造‐細胞傷害性相関解析2018
- Author(s)
  永井純子、史海霞、久保田夕香、坂東健二郎、奥平准之、植沢芳広、坂上宏、友村美根子、友村明人、高尾浩一、杉田義昭
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] 2-(N-cyclicamino)chromone誘導体の定量的構造‐細胞傷害性相関解析2018
- Author(s)
  植沢芳広、史海霞、永井純子、坂詰つかさ、坂東健二郎、坂上宏、友村美根子、友村明人、高尾浩一、杉田義昭
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] 3-(N-サイクリックアミノ)クロモン誘導体の定量的構造‐細胞傷害性相関解析2018
- Author(s)
  坂上宏、史海霞、永井純子、坂詰つかさ、坂東健二郎、奥平准之、植沢芳広、友村美根子、友村明人、高尾浩一、杉田義昭
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] ヒト口腔扁平上皮癌に対する高い選択性と、低いケラチノサイト毒性を有する新規クロモン誘導体の創製2018
- Author(s)
  坂上宏、史海霞、坂東健二郎、友村美根子、友村明人
- Organizer
  第60回日本歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] ササヘルスによるホルメシスおよび神経細胞保護効果の誘導2018
- Author(s)
  坂上宏、友村美根子、友村明人、増田宜子、横瀬敏志、岩間聡一、中川美香、鈴木隼人、田中健大、阿部智之、大石洋平、田村暢章、竹島浩、安井利一、辻まゆみ、木内祐二、小口勝司、堀内美咲、藤澤知弘、勝呂まどか、大泉浩史、大泉高明
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] 明海大学歯科医学総合研究所(M-RIO)の設立ー有害作用の少ない口腔疾患治療薬の開発をめざして2017
- Author(s)
  坂上宏、友村美根子、増田宜子
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] マスティック画分の生物活性の化学療法係数に基づいた再評価2017
- Author(s)
  坂上宏、鈴木龍一郎、天野滋、須永克佳、金本大、福地邦彦、寺久保繁美、白瀧義明、増田宜子、横瀬敏志、友村美根子、友村明人、中島秀喜、渡邉博文、大川原正喜、又平芳春
- Organizer
  第136会薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] フサザクラに含まれる骨芽細胞の分化を促進する化合物の探索2017
- Author(s)
  深見聡、鈴木龍一郎、友村美根子、友村明人、白瀧義明
- Organizer
  第６４回日本生薬学会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] ササヘルスのアミロイドペプチド誘発性神経細胞傷害に対する保護作用2017
- Author(s)
  岩間聡一、坂上宏、増田宜子、友村美根子、横瀬敏志、友村明人、中川美香、鈴木隼人、田中健大、阿部智之、大石洋平、田村暢章、竹島浩、鈴木龍一郎、白瀧義明、辻まゆみ、木内裕二、堀江憲夫、名取威徳、堀内美咲、勝呂まどか、大泉浩史、大泉高明
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] ピペリン酸エステル誘導体の構造活性相関：腫瘍選択性とアポトーシス誘導2017
- Author(s)
  坂上宏、植沢芳広、増田宜子、友村美根子、金本大成、寺久保繁美、宮城昂幹、村井淳一、高尾浩一、横瀬敏志、加賀谷肇、中島秀喜、杉田義昭
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] 骨芽細胞と破骨細胞におけるゲラニルゲラニオールの効果2016
- Author(s)
  友村美根子、坂東健二郎, 鈴木龍一郎, 白瀧義明, 坂上宏, 友村明人
- Organizer
  第89回　日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] LPS誘導性破骨細胞分化に対するカルデクリンの効果2016
- Author(s)
  川口祥子、坂東健二郎、田村暢章、友村美根子、友村明人,嶋田淳
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] 骨芽細胞を分化促進させる生薬の探索2016
- Author(s)
  深見聡、鈴木龍一郎、友村美根子、友村明人、坂上宏、白瀧義明
- Organizer
  第63回　日本生薬学会
- Place of Presentation
  富山
- Year and Date
  2016-09-24
- Data Source
  KAKENHI-PROJECT-16K11487
[Presentation] バイオイメージングによる破骨細胞のシグナル解析2013
- Author(s)
  長谷川紘也、,友村美根子、友村明人、須田直人
- Organizer
  第72回日本矯正歯科学会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-24659916
[Presentation] 血清カルシウム降下因子カルデクリンはRANKLによるSrc family kinaseを介する破骨細胞の分化を抑制する2013
- Author(s)
  友村明人, 坂上宏, 友村美根子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24592811
[Presentation] 血清カルシウム降下因子カルデクリンはRANKLによるTRAF6/Srcシグナル伝達を阻害することによって成熟破骨細胞の骨吸収機能を抑制する2012
- Author(s)
  友村明人、長谷川紘也、須田直人、坂上　宏、友村美根子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24592811
[Presentation] 血清カルシウム降下因子カルデクリンはRANKLのよるTRAF6/Srcシグナル伝達を阻害することによって成熟破骨細胞の骨吸収能を抑制する2012
- Author(s)
  友村明人、長谷川紘也、須田直人、坂上宏、友村美根子
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24659916
[Presentation] Serum Calcium-decreasing Factor, Caldecrin, Inhibits RANKL-mediated Ca2+ Signaling and Actin Ring Formation in Mature Osteoclasts via Suppression of the Src Signaling Pathway2012
- Author(s)
  友村明人、長谷川紘也、須田直人、坂上　宏、友村美根子
- Organizer
  米国骨代謝学会2012
- Place of Presentation
  アメリカ合衆国ミネアポリス
- Data Source
  KAKENHI-PROJECT-24592811
[Presentation] リナカンチンCはRANKLによるTRAF6-TAK1複合体形成を阻害し、破骨細胞の分化を抑制する
- Author(s)
  友村美根子, 鈴木龍一郎,渡部美緒,白瀧義明, 坂上宏, 友村明人
- Organizer
  第８7回日本生化学会大会
- Place of Presentation
  国立京都国際会館、京都市、京都府
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24592811
[Presentation] ラン科植物Odontioda Marie Noel ‘Velano’由来フェナンスレン類の破骨細胞分化抑制活性
- Author(s)
  渡部美緒，鈴木龍一郎, 友村美根子, 坂上宏, 友村明人, 白瀧義明
- Organizer
  第61回日本生薬学会
- Place of Presentation
  福岡大学、福岡市、福岡県
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-24592811
[Presentation] 血清カルシウム降下因子カルデクリンはRANKLによる細胞膜ラフト画分のFynの活性化を抑制して破骨細胞の分化を抑制する
- Author(s)
  友村明人, 長谷川紘也, 田村暢章, 須田直人, 友村美根子
- Organizer
  第８7回日本生化学会大会
- Place of Presentation
  国立京都国際会館、京都市、京都府
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24592811
[Presentation] 成熟破骨細胞の細胞内骨格に対するカルデクリンの影響
- Author(s)
  長谷川紘也, 須田直人, 友村明人
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場、福岡市、福岡県
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592811

1. TOMOMURA Mineko (30217559)

# of Collaborated Projects: 4 results

# of Collaborated Products: 45 results
2. INABA Akemi (50151585)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 坂東健二郎 (50347093)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
4. KATOH Setsuko (50049376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. FUJIMOTO Kengo (90286013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 鈴木龍一郎 (20415201)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
7. TAMURA Nobuaki (00363218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUDA Naoto (90302885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. ADACHI Kazunori (20349963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Hayashi Joichiro (50337507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. DAIKUHARA Yasushi (40028733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ARAKAKI Naokatu (60151148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAKAMURA Osamu (70128445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KIYOMURA Masaru (10337503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MANO Mikiko (00333005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NOIKURA Takenori (40102561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. IKIMORI Rie (90176074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KAWANO Kazunori (50108750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ITO Gakuji (60005064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NISHIMATA Hiroto (90117531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. OGATA Takahiko (80136887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. INOUE Masakazu (30028740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 申基てつ (40187555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 辰巳順一 (60227105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 谷田部一大 (00526551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 大西英知 (30580279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 福田正勝 (10311614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. HASEGAWA Naoya

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
29. 吉元絹代

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. YOSHIMOTO Kinuyo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. MILLER M.R

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. MILLER Margaret R.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. ARAKI Wataru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 長谷川紘也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 久永眞市

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akito TOMOMURA 友村 明人

友村 明人 トモムラ アキト

TOMOMURA Akito 友村 明人

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Inhibitory mechanism of caldecrin on RANKL-stimulated signaling platform formation in the osteoclastsPrincipal Investigator

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Searches for the molecular pathogenesis of skeretal and neuronal system from serum calcium-decreasing factor, caldecrin, knock out mousePrincipal Investigator

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Gene therapy with serum calcium-decreasing factor, caldecrin, for osteoporosisPrincipal Investigator

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Exploration of genes and the functions affected by serum calcium-decreasing factor (caldecrin)Principal Investigator

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Analysis of Receptor for Bone Resorption Suppressor CaldecrinPrincipal Investigator

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Akito TOMOMURA 友村明人

友村明人トモムラアキト

TOMOMURA Akito 友村明人