Mishima Michiaki 三嶋理晃

… Alternative Names

MISHIMA Michiaki 三嶋理晃

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Researcher Number	60190625
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 名誉教授
Affiliation (based on the past Project Information) *help	2018: 京都大学, 医学(系)研究科(研究院), 教授 2016 – 2017: 京都大学, 医学研究科, 名誉教授 2015 – 2016: 京都大学, 医学(系)研究科(研究院), 名誉教授 2011 – 2016: 京都大学, 医学(系)研究科(研究院), 教授 2014: 京都大学, 医学研究科, 教授 … More 2001 – 2011: Kyoto University, Medicine, Professor, 医学研究科, 教授 2010: 京都大学, 医学研究科呼吸器内科, 教授 2008: Kyoto University, 大学院・医学研究科, 教授 2000: 京都大学, 医学研究科, 助教授 1999: 京都大学, 大学院・医学研究科, 助教授 1996 – 1997: 京都大学, 胸部疾患研究所, 助教授 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine / Science and Engineering / Infectious disease medicine
Keywords	Principal Investigator COPD / 慢性閉塞性肺疾患 / LAA% / 気道病変 / 胸部CT / フラクタル解析 / CT / 肺気腫 / iPS細胞 / 遺伝子多型 … More / 分子細胞呼吸器学 / 疾患モデリング / 肺臓器再生 / 分子細胞呼吸学 / airway reversibility / gene polymorphism / MMP-9 / Gc-Globulin / emphysema / airway disorder / TGFβ / IL15 / IL8 / LVRS / 誘発喀痰 / 肺気腫病変 / CT画像 / klothoマウス / IOS / イプラトロピウム / サルブタモール / 気道肥厚 / フラクタル次元 / COPD患者 / 気道可逆性 / MMP9 / Gcグロブリン / 気腫病変 / Fractal analysis / Chronic Bronchitis / Pulmonary Emphysema / 気管 / 気道壁 / WA% / 低吸収領域 / 慢性気管支炎 / contractilc interstitial cell / histamine, / lung elastance, / lung resistance, / 肺エラスタンス / 肺レジスタンス / 低酸素 / 家兎 / 肺間質細胞 / 収縮性間質細胞 / ヒスタミン / 肺弾性抵抗 / 肺粘性抵抗 / Birt-Hogg-Dube症候群 / 分化誘導 / I型肺胞上皮細胞 / 疾患特異的iPS / リンパ脈管筋腫症 / 若年性肺気腫 / 特発性間質性肺炎 / 肺胞上皮細胞 / 疾患特異iPS / 嚢胞性線維症 / Hermansky-Pudlak 症候群 / ３次元培養 / carboxypeptidase M / surfactant protein C / II型肺胞上皮細胞 / ES細胞 / 肺障害 / 細胞培養 / 動物モデル / phenotyping / リモデリング / 骨そしょう症 / 胃食道逆流 / 体重減少 / 炎症 / 画像診断 … More Except Principal Investigator 慢性閉塞性肺疾患 / ALT / AST / QT dispersion / ES細胞 / 肺胞上皮細胞 / iPS細胞 / 気道上皮細胞 / COPD / サーファクタントプロテインC / II型肺胞上皮細胞 / morphology / pulmonary function / genetics / computed tomography / inflammation / emphysema / airway remodeling / 呼吸生理 / 肺気腫モデル動物 / 組織バンク / 病理組織 / 形態学 / 遺伝子発現 / 形態 / 呼吸機能 / 遺伝子解析 / CT / 炎症 / 気腫病変 / 気道病変 / fatty liver / leptin / MIBG cardiac imaging / nCPAP / obstructive sleep apnea-hypopnea syndrome / 心臓交感神経機能 / MIBG心筋シンチ / 閉塞性睡眠時無呼吸低呼吸症候(OSAHS) / 脂肪肝 / レプチン / MIBG 心筋シンチ / 経鼻持続気道陽圧(nCPAP) / 閉塞性睡眠時無呼吸低呼吸症候群(OSAHS) / microfluidics / nanofiber / 血管内皮細胞 / 線毛上皮細胞 / 再生医学 / 肺気腫 / 呼吸器疾患 / ナノファイバー / 肺前駆細胞 / マルチスケール・マルチモダリティ画像 / 肺・大腸・肝臓に発生する悪性腫瘍の本態解明 / 3次元ミクロからマクロの病態 / 肺を中心に大腸・腎臓に発生する悪性腫瘍の本態解明 / マルチスケール・マルチモダリティ画像データベース / 腫瘍診断支援システム / 多元計算解剖モデル / 病原性 / 感染疫学 / 環境曝露 / VNTR / ヒトiPS細胞 / SOX2 / FOXA2 / 前腸細胞 / SP-C / NKX2.1 / SPC / レポーター細胞 / サーファクタント / 組織幹細胞 / MAPK / 歯周病 / 気道炎症 / 感染 / 宿主免疫 / 慢性感染 / COPD増悪 / 末梢気道 / 気管支喘息 / 上皮間葉移行 Less

Application of iPS cell technology to lung regeneration and development of bioresource for elucidating the mechanisms of lung diseasesPrincipal Investigator
- Principal Investigator
  
  Michiaki Mishima
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Cancer Diagnosis and Prognosis Assistance Based on Multidisciplinary Computational Anatomy
- Principal Investigator
  
  Niki Noboru
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokushima
Double-face culture system for application of alveolar epithelial cells induced from human iPS cells
- Principal Investigator
  
  Isao Ito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Searching for pathogenic genes of MAC strains transmitted from environments
- Principal Investigator
  
  YUTAKA Ito
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagoya City University
  Kyoto University
Challenge to search for lung progenitor cells and to develop alveolar type II cells from human iPS cells
- Principal Investigator
  
  ITO Isao
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Researches using iPS cells on intractable respiratory diseases to elucidate their pathogenesis and develop novel therapy.Principal Investigator
- Principal Investigator
  
  MISHIMA MICHIAKI
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Chronic infection and immune response in COPD patients
- Principal Investigator
  
  MURO Shigeo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Mechanisms in epithelial-mesenchymal transition in chronic obstructive pulmonary disease
- Principal Investigator
  
  ITO Isao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Comprehensive study on the phenotyping of COPDPrincipal Investigator
- Principal Investigator
  
  MISHIMA Michiaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Integrated comparison among lung histology of human early emphysema, clinical parameters, and mechanics and model animals
- Principal Investigator
  
  MURO Shigeo
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Study on the COPD therapy based on the airway dimension measured by CT imagingPrincipal Investigator
- Principal Investigator
  
  MISHIMA Michiaki
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
QTc Dispersion, Cardiac Sympathetic Functionand Secretion of Leptin in Patients with Obstructive Sleep Apnea.
- Principal Investigator
  
  CHIN Kazuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  KYOTO UNIVERSITY
Analysis of Emphysema and Airway Lesion in Patients with COPDPrincipal Investigator
- Principal Investigator
  
  MISHIMA Michiaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  KYOTO UNIVERSITY
Acute response of lung mechanics to hypoxia and histaminePrincipal Investigator
- Principal Investigator
  
  MISHIMA Michiaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  KYOTO UNIVERSITY

[Journal Article] Long-term expansion of alveolar stem cells derived from human iPS cells in organoids2017
- Author(s)
  Yamamoto Yuki、Gotoh Shimpei、Korogi Yohei、Seki Masahide、Konishi Satoshi、Ikeo Satoshi、Sone Naoyuki、Nagasaki Tadao、Matsumoto Hisako、Muro Shigeo、Ito Isao、Hirai Toyohiro、Kohno Takashi、Suzuki Yutaka、Mishima Michiaki
- Journal Title
  
  Nature Methods
  
  Volume: 14 Issue: 11 Pages: 1097-1106
- DOI
  10.1038/nmeth.4448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09536, KAKENHI-PROJECT-15H02537, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17H05084
[Journal Article] Three-dimensional imaging forced oscillation technique to assess position-dependent airway obstruction in relapsing polychondritis; a case report.2017
- Author(s)
  Kamada T, Ito I, Kanemitsu Y, Sato S, Matsumoto H, Niimi A, Mishima M.
- Journal Title
  
  Respir Investig
  
  Volume: 55 Issue: 1 Pages: 69-73
- DOI
  10.1016/j.resinv.2016.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293199, KAKENHI-PROJECT-16K15457
[Journal Article] CT-assessed large airway involvement and lung function decline in eosinophilic asthma: The association between induced sputum eosinophil differential counts and airway remodeling.2016
- Author(s)
  Inoue H, Ito I, Niimi A, Matsumoto H, Matsuoka H, Jinnai M, Takeda T, Oguma T, Otsuka K, Nakaji H, Tajiri T, Iwata T, Nagasaki T, Kanemitsu Y, Mishima M.
- Journal Title
  
  J Asthma
  
  Volume: 53 Issue: 9 Pages: 914-21
- DOI
  10.3109/02770903.2016.1167903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293199, KAKENHI-PROJECT-16K15457
[Journal Article] Directed induction of functional multi-ciliated cells in proximal airway epithelial spheroids from human pluripotent stem cells.2016
- Author(s)
  Konishi S, Gotoh S, Tateishi K, Yamamoto Y, Korogi Y, Matsumoto H, Muro S, Hirai T, Ito I, Tsukita S, Mishima M.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 6 Issue: 1 Pages: 18-25
- DOI
  10.1016/j.stemcr.2015.11.010
- NAID
  120005745633
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21114, KAKENHI-PROJECT-15H02537, KAKENHI-PROJECT-25461156, KAKENHI-PROJECT-26293199, KAKENHI-PROJECT-16K15457
[Journal Article] Emphysema and airway disease affect within-breath changes in　respiratory resistance in COPD patients.2015
- Author(s)
  Hasegawa K, Sato S, Tanimura K, Fuseya Y, Uemasu K, Sato A, Hirai T, Mishima M, Muro S
- Journal Title
  
  Respirology
  
  Volume: - Issue: 5 Pages: 775-81
- DOI
  10.1111/resp.12535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22249031, KAKENHI-PROJECT-25461156
[Journal Article] ヒト多能性幹細胞からⅡ型肺胞上皮細胞への分化促進と単離2015
- Author(s)
  後藤慎平, 三嶋理晃
- Journal Title
  
  呼吸と循環
  
  Volume: 63 Pages: 651-655
- NAID
  40020519047
- Data Source
  KAKENHI-PROJECT-15H02537
[Journal Article] A toll-like receptor 3 single nucleotide polymorphism in　Japanese patients with sarcoidosis.2015
- Author(s)
  Ikezoe K, Handa T, Tanizawa K, Kubo T, Ito I, Sokai A, Nakatsuka Y, Nagai S, Izumi T, Mishima M
- Journal Title
  
  Tissue Antigens
  
  Volume: 85 Issue: 3 Pages: 204-208
- DOI
  10.1111/tan.12535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22249031, KAKENHI-PROJECT-25860642, KAKENHI-PROJECT-26461187, KAKENHI-PROJECT-15H02537
[Journal Article] The influence of environmental exposure on the response to antimicrobial treatment in pulmonary Mycobacterial avium complex disease2014
- Author(s)
  Yutaka Ito, Toyohiro Hirai, Kohei Fujita, Takeshi Kubo, Koichi Maekawa, Satoshi Ichiyama, Kaori Togashi, Michiaki Mishima
- Journal Title
  
  BMC Infectious diseases
  
  Volume: 14 Issue: 1 Pages: 522-528
- DOI
  10.1186/1471-2334-14-522
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591479, KAKENHI-PROJECT-25461818
[Journal Article] Association between polyclonal and mixed mycobacterial Mycobacterium avium complex infection and environmental exposure.2014
- Author(s)
  Fujita K, Ito Y, Hirai T, Kubo T, Maekawa K, Togashi K, Ichiyama S, Mishima M.
- Journal Title
  
  Ann Am Thorac Soc.
  
  Volume: 11 Issue: 1 Pages: 45-53
- DOI
  10.1513/annalsats.201309-297oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591479, KAKENHI-PROJECT-25461818
[Journal Article] Prevalence and clinical relevance of allergic rhinitis in patients with classic asthma and cough variant asthma2014
- Author(s)
  Tajiri T, Niimi A, Matsumoto H, Ito I, Oguma T, Otsuka K, Takeda T, Nakaji H, Inoue H, Iwata T, Nagasaki T, Mishima M
- Journal Title
  
  Respiration
  
  Volume: 87 Pages: 211-8
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Isolation of drug-resistant pathogens does not always require use of broad-spectrum antibiotics in pneumonia2014
- Author(s)
  Ito I, Mishima M
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 189 Pages: 756-7
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Integrating longitudinal information on pulmonary function and inflammation using asthma phenotypes.2014
- Author(s)
  Nagasaki T, Matsumoto H, Kanemitsu Y, Izuhara K, Tohda Y, Kita H, Horiguchi T, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Ito I, Oguma T, Inoue H, Tajiri T, Iwata T, Izuhara Y, Ono J, Ohta S, Yokoyama T, Niimi A, Mishima M
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 133 Issue: 5 Pages: 1474-1477
- DOI
  10.1016/j.jaci.2013.12.1084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22249031, KAKENHI-PROJECT-23591117, KAKENHI-PROJECT-23591120, KAKENHI-PROJECT-23591142, KAKENHI-PROJECT-23591146, KAKENHI-PROJECT-24591466
[Journal Article] Neutrophil gelatinase-associated lipocalin in idiopathic pulmonary fibrosis2014
- Author(s)
  Ikezoe K, Mishima M, et al.
- Journal Title
  
  Eur Respir J
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031
[Journal Article] Osteopontin and periostin are associated with a 20-year decline of pulmonary function in patients with asthma.2014
- Author(s)
  Kanemitsu Y, Ito I, Niimi A, Izuhara K, Ohta S, Ono J, Iwata T, Matsumoto H, Mishima M
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 190 Issue: 4 Pages: 472-474
- DOI
  10.1164/rccm.201403-0562le
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22249031, KAKENHI-PROJECT-23591117, KAKENHI-PROJECT-24591466, KAKENHI-PROJECT-25293224
[Journal Article] Generation of alveolar epithelial spheroids via isolated progenitor cells from human pluripotent stem cells.2014
- Author(s)
  Gotoh S, Ito I, Nagasaki T, Yamamoto Y, Konishi S, Korogi Y, Matsumoto H, Muro S, Hirai T, Funato M, Mae S, Toyoda T, Sato-Otsubo A, Ogawa S, Osafune K, Mishima M
- Journal Title
  
  Stem Cell Reports
  
  Volume: 3 Issue: 3 Pages: 394-403
- DOI
  10.1016/j.stemcr.2014.07.005
- NAID
  120005477388
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22249031, KAKENHI-PROJECT-26293199
[Journal Article] p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice.2014
- Author(s)
  Marumo S, Hoshino Y, Kiyokawa H, Tanabe N, Sato A, Ogawa E, Muro S, Hirai T, Mishima M
- Journal Title
  
  BMC Pulm Med
  
  Volume: 14 Issue: 1
- DOI
  10.1186/1471-2466-14-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031
[Journal Article] Neutrophil gelatinase-associated lipocalin in idiopathic pulmonary fibrosis.2014
- Author(s)
  Ikezoe K, Handa T, Mori K, Watanabe K, Tanizawa K, Aihara K, Tsuruyama T, Miyagawa-Hayashino A, Sokai A, Kubo T, Muro S, Nagai S, Hirai T, Chin K, Mishima M
- Journal Title
  
  Eur Respir J
  
  Volume: 43 Issue: 6 Pages: 1807-1809
- DOI
  10.1183/09031936.00192613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031, KAKENHI-PROJECT-23390225, KAKENHI-PROJECT-25461818, KAKENHI-PROJECT-25860642, KAKENHI-PROJECT-26460450
[Journal Article] Osteopontin and periostin associate with a 20-year decline of pulmonary function in asthmatics2014
- Author(s)
  Kanemitsu Y, Ito I, Niimi A, Izuhara K, Ohta S, Ono J, IwataT, Matsumoto H, Mishima M
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: (accepted)
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Effects of 24-week add-on treatment with ciclesonide and montelukast on small airways inflammation in asthma2013
- Author(s)
  Nakaji H, Petrova G, Matsumoto H, Iwata T, Ito I, Oguma T, Inoue H, Tajiri T, Nagasaki T, Kanemitsu Y, Niimi A, Mishima M
- Journal Title
  
  Ann Allergy Asthma Immunol
  
  Volume: 110 Pages: 198-203
- NAID
  120005244569
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Thioredoxin-1 protects against neutrophilic inflammation and emphysema progression in a mouse model of chronic obstructive pulmonary disease2013
- Author(s)
  Tanabe N, Mishima M,et al
- Journal Title
  
  Plos One
  
  Volume: なし Issue: 11 Pages: e79016-e79016
- DOI
  10.1371/journal.pone.0079016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031
[Journal Article] Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids2013
- Author(s)
  Kanemitsu Y, Mishima M,et al.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 132 Issue: 2 Pages: 305-312
- DOI
  10.1016/j.jaci.2013.04.050
- NAID
  120005342661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031, KAKENHI-PROJECT-23591117, KAKENHI-PROJECT-23591120, KAKENHI-PROJECT-23591142, KAKENHI-PROJECT-24591466, KAKENHI-PROJECT-24659405, KAKENHI-PROJECT-25293224
[Journal Article] Interferon regulatory factor 5 polymorphisms in sarcoidosis2013
- Author(s)
  Tanizawa K, Handa T, Nagai S, Sato H, Yamada R, Ito I, Kubo T, Ito Y, Watanabe K, Aihara K, Ikezoe K, Mishima M, Izumi T
- Journal Title
  
  Mod Rheumatol
  
  Volume: 23 Pages: 1158-65
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Association of eosinophilic inflammation with FKBP51 expression in sputum cells in asthma2013
- Author(s)
  Tajiri T, Matsumoto H, Niimi A, Ito I, Oguma T, Nakaji H, Inoue H, Iwata T, Nagasaki T, Kanemitsu Y, Petrova G, Mishima M
- Journal Title
  
  PLoS One
  
  Volume: 8
- NAID
  120005296109
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Smoking attenuates the age-related decrease in IgE levels and maintains eosinophilic inflammation2013
- Author(s)
  Nagasaki T, Matsumoto H, Nakaji H, Niimi A, Ito I, Oguma T, Muro S, Inoue H, Iwata T, Tajiri T, Kanemitsu Y, Mishima M
- Journal Title
  
  Clin Exp Allergy
  
  Volume: 43 Pages: 608-15
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Genetic relatedness of Mycobacterium avium-intracellulare complex isolates from patients with pulmonary MAC disease and their residential soils.2013
- Author(s)
  Fujita K, Ito Y, Hirai T, Maekawa K, Imai S, Tatsumi S, Niimi A, Iinuma Y, Ichiyama S, Mishima M.
- Journal Title
  
  Clin Microbiol Infect.
  
  Volume: 19 Issue: 6 Pages: 537-541
- DOI
  10.1111/j.1469-0691.2012.03929.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591479
[Journal Article] Computed tomography assessment of pharmacological lung volume reduction induced by bronchodilators in COPD2012
- Author(s)
  Tanabe N, Muro S, Oguma T, Sato S, Kiyokawa H, Takahashi T, Kudo M, Kinose D, Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M. COPD
- Journal Title
  
  COPD
  
  Volume: 9 Issue: 4 Pages: 1-8
- DOI
  10.3109/15412555.2012.674986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964, KAKENHI-PROJECT-22249031
[Journal Article] A NOD2 gene polymorphism is associated with the prevalence and severity of chronic obstructive pulmonary disease in a Japanese population2012
- Author(s)
  Kinose D, Ogawa E, Hirota T, Ito I, Kudo M, Haruna A, Marumo S, Hoshino Y, Muro S, Hirai T, Sakai H, Date H, Tamari M, Mishima M
- Journal Title
  
  Respirology
  
  Volume: 17(1) Issue: 1 Pages: 164-71
- DOI
  10.1111/j.1440-1843.2011.02069.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964, KAKENHI-PROJECT-23791204
[Journal Article] Sputum YKL-40 Levels and Pathophysiology of Asthma and Chronic Obstructive Pulmonary Disease2012
- Author(s)
  Otsuka K, Matsumoto H, Niimi A, Muro S, Ito I, Takeda T, Terada K, Yamaguchi M, Matsuoka H, Jinnai M, Oguma T, Nakaji H, Inoue H, Tajiri T, Iwata T, Chin K, Mishima M
- Journal Title
  
  Respiration
  
  Volume: 83 Pages: 507-19
- NAID
  120004397864
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Emphysema distribution and annual changes in pulmonary function in male patients with chronic obstructive pulmonary disease2012
- Author(s)
  Tanabe N, Muro S, Tanaka S, Sato S, Oguma T, Kiyokawa H, Takahashi T, Kinose D, Hoshino Y, Kubo T, Ogawa E, Hirai T, Mishima M. Respir Res
- Journal Title
  
  Epub ahead of print
  
  Volume: 13(1) Issue: 1 Pages: 31-31
- DOI
  10.1186/1465-9921-13-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Increase in circulating endothelial progenitor cells predicts response in patients with advanced non-small-cell lung cancer2012
- Author(s)
  im YH, Ichiyama S, Mishima M, et al
- Journal Title
  
  Cancer Sci
  
  Volume: 1 Issue: 6 Pages: 24-30
- DOI
  10.1111/j.1349-7006.2012.02249.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031
[Journal Article] Clinical features and risk factors of tuberculosis in living-donor liver transplant recipients2012
- Author(s)
  Imai S, Ito Y, Hirai T, Imai H, Ito I, Maekawa K, Chin K, Ichiyama S, Uemoto S, Mishima M
- Journal Title
  
  Transpl Infect Dis
  
  Volume: 14 Pages: 9-16
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Impact of COPD Exacerbations on Osteoporosis Assessed by Chest CT Scan2012
- Author(s)
  Kiyokawa H, Muro S, Oguma T, Sato S, Tanabe N, Takahashi T, Kudo M, Kinose D, Kondoh H, Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M
- Journal Title
  
  Epub
  
  Volume: 9(3) Issue: 3 Pages: 235-42
- DOI
  10.3109/15412555.2011.650243
- NAID
  120004873856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964, KAKENHI-PROJECT-21591559, KAKENHI-PROJECT-22590861
[Journal Article] Pulmonary hemorrhage induced by epileptic seizure2012
- Author(s)
  Azuma M, Ito I, Matsumoto R, Hirai T, Mishima M
- Journal Title
  
  Heart Lung
  
  Volume: 40 Pages: 290-3
- NAID
  120004140499
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Oxidative stress induced Interleukin-32 mRNA expression in human bronchial epithelial cells2012
- Author(s)
  Kudo M, Ogawa E, Kinose D, Haruna A, Takahashi T, Tanabe N, Marumo S, Hoshino Y, Hirai T, Sakai H, Muro S, Date H, Mishima M
- Journal Title
  
  Respir Res
  
  Volume: 13 Issue: 1 Pages: 19-19
- DOI
  10.1186/1465-9921-13-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Association between vascular-poor area of primary tumors and epidermal growth factor receptor gene status in advanced lung adenocarcinoma2012
- Author(s)
  Togashi Y, Kubo T, et al.
- Journal Title
  
  Med Oncol
  
  Volume: なし Issue: 5 Pages: 3169-3175
- DOI
  10.1007/s12032-012-0235-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591559, KAKENHI-PROJECT-22249031
[Journal Article] Eosinophils and macrophages are involved in nitrosative stress in chronic eosinophilic pneumonia.2011
- Author(s)
  Nakaji H, Matsumoto H, Niimi A, Handa T, Ito I, Kanai M, Tabata H, Sakai H, Kobashi Y, Mochizuki Y, Chin K, Mishima M.
- Journal Title
  
  Nitric Oxide : Biology and Chemistry accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] A CD40 single nucleotide polymorphis affects the lymphocyte profiles in the bronchoalveolar lavage of Japanese patients with sarcoidosis2011
- Author(s)
  Tanizawa K, Handa T, Nagai S, Ito I, Takeshi K, Ito Y, Watanabe K, Aihara K, Mishima M, Izumi T
- Journal Title
  
  Tissue Antigens
  
  Volume: 78 Pages: 442-5
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Association of the transforming growth factor β1 promoter polymorphism, C-509T, with smoking status and survival in advanced non-small cell lung cancer. Oncol Rep2011
- Author(s)
  Togashi Y, Masago K, Fujita S, Kim YH, Sakamori Y, Hatachi Y,Fukuhara A, Nagai H, Mio T, Mishima M
- Journal Title
  
  Oncol Rep
  
  Volume: 25(2) Pages: 377-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031
[Journal Article] To authors reply. invasive mechanical ventilation in patients with idiopathic pulmonary fibrosis or idiopathic non-specific interstitial pneumonia2011
- Author(s)
  Tomii K, Tachikawa R, Chin K, Murase K, Handa T, Mishima M, Ishihara K
- Journal Title
  
  Intern Med
  
  Volume: 50(2) Pages: 175-175
- NAID
  130000413224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031
[Journal Article] Impact of exacerbations on emphysema progression in chronic obstructive pulmonary disease2011
- Author(s)
  Tanabe N, Muro S, Hirai T, Oguma T, Terada K, Marumo S, Kinose D, Ogawa E, Hoshino Y, Mishima M
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 183(12) Issue: 12 Pages: 1653-9
- DOI
  10.1164/rccm.201009-1535oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Tazobactam/piperacillin for moderate-to-severe pneumonia in patients with risk for aspiration : comparison with imipenem/cilastatin2010
- Author(s)
  Ito I, Kadowaki S, Tanabe N, Haruna A, Kase M, Yasutomo Y, Tsukino M, Nakai A, Matsumoto H, Niimi A, Chin K, Ichiyama S, Mishima M
- Journal Title
  
  Pulm Pharmacol Ther
  
  Volume: 23 Pages: 403-10
- NAID
  120002484950
- Data Source
  KAKENHI-PROJECT-23591146
[Journal Article] Association of alveolar nitric oxide levels with pulmonary function and its reversibility in stable asthma.2010
- Author(s)
  Matsumoto H, Niimi A, Jinnai M, Nakaji H, Takeda T, Oguma T, Otsuka K, Inoue H, Yamaguchi M, Matsuoka H, Ito I, Hirai T, Chin K, Mishima M.
- Journal Title
  
  Respiration Epub ahead of print
- NAID
  120005593637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Induced sputum concentrations of mucin in patients with asthma and chronic cough.2010
- Author(s)
  Jinnai M, Niimi A, Ueda T, Matsuoka H, Takemura M, Yamaguchi M, Otsuka K, Oguma T, Takeda T, Ito I, Matsumoto H, Mishima M.
- Journal Title
  
  Chest 137
  
  Pages: 1122-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Distribution and clonal relationship of cell surface virulence genes among Streptococcus pneumoniae isolates in Japan.2010
- Author(s)
  Imai S, Ito Y, Ishida T, Hirai T, Ito I, Yoshimura K, Maekawa K, Takakura S, Niimi A, Iinuma Y, Ichiyama S, Mishima M ; the Kansai Community Acquired Pneumococcal Pneumonia Study Group.
- Journal Title
  
  Clin Microbiol Infect. Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Lipopolysaccharide induced connective tissue growth factor gene expression in human bronchial epithelial cells.2010
- Author(s)
  Nishioka M, Ogawa E, Kinose D, Haruna A, Ohara T, Ito I, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Hirai T, Muro S, Mishima M.
- Journal Title
  
  Respirology 15
  
  Pages: 669-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Tazobactam/piperacillin for moderate-to-severe pneumonia in patients with risk for aspiration : comparison with imipenem/cilastatin.2010
- Author(s)
  Ito I, Kadowaki S, Tanabe N, Haruna A, Kase M, Yasutomo Y, Tsukino M, Nakai A, Matsumoto H, Niimi A, Chin K, Ichiyama S, Mishima M.
- Journal Title
  
  Pulm Pharmacol Ther 23
  
  Pages: 403-10
- NAID
  120002484950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Genetic polymorphisms in the endothelial nitric oxide synthase gene correlate with overall survival in advanced non-small-cell lung cancer patients treated with platinum-based doublet chemotherapy2010
- Author(s)
  Fujita S, Masago K, Hatachi Y, Fukuhara A, Hata A, Kaji R, Kim YH, Mio T, Mishima M, Katakami N
- Journal Title
  
  BMC Med Genet
  
  Volume: 11 Pages: 167-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249031
[Journal Article] Inflammatory subtypes in cough variant asthma : Association with maintenance doses of inhaled corticosteroids.2010
- Author(s)
  Matsuoka H, Niimi A, Matsumoto H, Takemura M, Ueda T, Yamaguchi M, Jinnai M, Inoue H, Ito I, Chin K, Mishima M.
- Journal Title
  
  Chest 138
  
  Pages: 1418-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Molecular characterization of quinolone resistance-determining regions and their correlation with serotypes and genotypes among Streptococcus pneumoniae isolates in Japan.2010
- Author(s)
  Osawa M, Ito Y, Ishida T, Imai S, Ichiyama S, Mishima M ; Kansai Community Acquired Pneumococcal Pneumonia Study Group.
- Journal Title
  
  Eur J Clin Microbiol Infect Dis 29
  
  Pages: 245-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Relationship between peripheral airway function and patient-reported outcomes in COPD : a cross-sectional study2010
- Author(s)
  Haruna A, Oga T, Muro S, Ohara T, Sato S, Marumo S, Kinose D, Terada K, Nishioka M, Ogawa E, Hoshino Y, Hirai T, Chin K, Mishima M
- Journal Title
  
  BMC Pulm Med
  
  Volume: 10 Issue: 1 Pages: 10-10
- DOI
  10.1186/1471-2466-10-10
- NAID
  120004754366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Lipopolysaccharide induced connective tissue growth factor gene expression in human bronchial epithelial cells2010
- Author(s)
  Nishioka M, Ogawa E, Kinose D, Haruna A, Ohara T, Ito I, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Hirai T, Muro S, Mishima M
- Journal Title
  
  Respirology
  
  Volume: 15(4) Pages: 669-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Abnormal swallowing reflex and COPD exacerbations2010
- Author(s)
  Terada K, Muro S, Ohara T, Kudo M, Ogawa E, Hoshino Y, Hirai T, Niimi A, Chin K, Mishima M
- Journal Title
  
  Chest
  
  Volume: 137(2) Issue: 2 Pages: 326-32
- DOI
  10.1378/chest.09-0482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] CT scan findings of emphysema predict mortality in COPD2010
- Author(s)
  Haruna A, Muro S, Nakano Y, Ohara T, Hoshino Y, Ogawa E, Hirai T, Niimi A, Nishimura K, Chin K, Mishima M
- Journal Title
  
  Chest
  
  Volume: 138(3) Issue: 3 Pages: 635-40
- DOI
  10.1378/chest.09-2836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] Relationship between Small Airway Function and Health Status, Dyspnea and Disease Control in Asthma.2010
- Author(s)
  Takeda T, Oga T, Niimi A, Matsumoto H, Ito I, Yamaguchi M, Matsuoka H, Jinnai M, Otsuka K, Oguma T, Nakaji H, Chin K, Mishima M.
- Journal Title
  
  Respiration 80
  
  Pages: 120-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Specific IgE response to Trichophyton and asthma severity.2009
- Author(s)
  Matsuoka H, Niimi A, Matsumoto H, Ueda T, Takemura M, Yamaguchi M, Jinnai M, Otsuka K, Oguma T, Takeda T, Ito I, Chin K, Amitani R, Mishima M.
- Journal Title
  
  Chest 135
  
  Pages: 898-903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Features of cough variant asthmaand classic asthma duringmethacholine-inducedbrochoconstriction : a cross-sectional study2009
- Author(s)
  Matsumoto H, Niimi A, Takemura M, Ueda T,Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Mishima M
- Journal Title
  
  Cough
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Features of cough variant asthma and classic asthma during methacholine-induced brochoconstriction : a cross-sectional study2009
- Author(s)
  Matsumoto H, Niimi A, Takemura M, Ueda T, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Mishima M.
- Journal Title
  
  Cough. 9 ; 5:3
- NAID
  120004770219
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Specific IgE response to trichophyton and asthma severity2009
- Author(s)
  Matsuoka H, Niimi A, Matsumoto H, Ueda T,Takemura M, Yamaguchi M, Jinnai M,, Otsuka K,Oguma T, Takeda T, Ito I, Chin K, Amitani R,Mishima M
- Journal Title
  
  Chest 135(4)
  
  Pages: 898-903
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Differentiation of bacterial and non-bacterial community-acquired pneumonia by thin-section computed tomography.2009
- Author(s)
  Ito I, Ishida T, Togashi K, Niimi A, Koyama H, Ishimori T, Kobayashi H, Mishima M.
- Journal Title
  
  Eur J Radiol 72
  
  Pages: 388-95
- NAID
  120002576696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Eosinophilic airway disorders associated withchronic cough2009
- Author(s)
  Niimi A, Matsumoto H, Mishima M
- Journal Title
  
  Pulm Pharmacol Ther 22(2)
  
  Pages: 114-20
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Cough-reflex sensitivity to inhaled capsaicin in COPD associated with increased exacerbation frequency2009
- Author(s)
  Terada K, Muro S, Ohara T, Haruna A, Marumo S, Kudo M, Ogawa E, Hoshino Y, Hirai T, Niimi A, Mishima M
- Journal Title
  
  Respirology
  
  Volume: 14(8) Issue: 8 Pages: 1151-5
- DOI
  10.1111/j.1440-1843.2009.01620.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590964
[Journal Article] High prevalence of multidrug-resistant Pneumococcal molecular epidemiology network clones among Streptococcus pneumoniae isolates from adult patients with community-acquired pneumonia in Japan.2009
- Author(s)
  Imai S, Ito Y, Ishida T, Hirai T, Ito I, Maekawa K, Takakura S, Iinuma Y, Ichiyama S, Mishima M, Kansai Community Acquired Pneumococcal Pneumonia Study Group.
- Journal Title
  
  Clin Microbiol Infect 15
  
  Pages: 1039-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Body mass index in male patients with COPD : correlation with low attenuation areas on CT.2009
- Author(s)
  Ogawa E, Nakano Y, Ohara T, Muro S, Hirai T,Sato S, Sakai H, Tsukino M, Kinose D, NishiokaM, Niimi A, Chin K, Par 辿 PD, Mishima M.
- Journal Title
  
  Thorax 64(1)
  
  Pages: 20-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Eosinophilic airway disorders associated with chronic cough.2009
- Author(s)
  Niimi A, Matsumoto H, Mishima M.
- Journal Title
  
  Pulm Pliarmacol Ther. 22(2)
  
  Pages: 114-20
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Body mass index in male patients with COPD : correlation with low attenuation areas on CT.2009
- Author(s)
  Ogawa E, Nakano Y, Ohara T, Muro S, Hirai T, Sato S, Sakai H, Tsukino M, Kinose D, Nishioka M, Niimi A, Chin K, Pare PD, Mishima M.
- Journal Title
  
  Thorax 64(1)
  
  Pages: 20-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Effect of inhaled corticosteroids on small airways in asthma : investigation using impulse oscillometry.2009
- Author(s)
  Yamaguchi M, Niimi A, Ueda T, Takemura M, Matsuoka H, Jinnai M, Otsuka K, Oguma T, Takeda T, Ito I, Matsumoto H, Hirai T, Chin K, Mishima M.
- Journal Title
  
  Pulm Pharmacol Ther 26
  
  Pages: 326-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Specific IgE response to trichophyton and asthma severity.2009
- Author(s)
  Matsuoka H, Niimi A, Matsumoto H, Ueda T, Takemura M, Yamaguchi M, Jinnai M, Otsuka K, Oguma T, Takeda T, I to I, Chin K, Amitani R, Mishima M.
- Journal Title
  
  Chest. 135 (4)
  
  Pages: 898-903
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Sputum levels of transforming growth factor-b1 in asthma : Relation to clinicoradiological findings.2008
- Author(s)
  Yamaguchi M, Niimi A, Matsumoto H, Ueda T, Takemura M, Matsuoka H, Jinnai M, Otsuka K, Oguma T, Takeda T, Ito I, Chin K, Mishima M.
- Journal Title
  
  J Investig Allergol Clin Immunol 18
  
  Pages: 202-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] TGFB1 promoter polymorphism C-509T and pathophysiology of asthma.2008
- Author(s)
  Ueda T, Niimi A, Matsumoto H, Takemura M, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Minakuchi M, Cheng L, Shirakawa T, Mishima
- Journal Title
  
  J Allergy Clin Immunol. 121(3)
  
  Pages: 659-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Gastroesophageal reflux-associated chronic cough in an adolescent and thediagnostic implications : a case report2008
- Author(s)
  Jinnai M, Niimi A, Takemura M, Matsumoto H, Konda Y, Mishima M.
- Journal Title
  
  Cough. 15 ; 4:5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice2008
- Author(s)
  Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J.
- Journal Title
  
  J Pharmacol Exp Ther. 325(2)
  
  Pages: 380-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] TGFB1 promoter polymorphism C-509T and pathophysiology of asthma.2008
- Author(s)
  Ueda T, Niimi A, Matsumoto H, Takemura M, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Minakuchi M, Cheng L, Shirakawa T, Mishima M.
- Journal Title
  
  J Allergy Clin Immunol. 121(3)
  
  Pages: 659-64
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography2008
- Author(s)
  Ohara T, Hirai T, Sato S, Terada K, Kinose D, Haruna A, Marumo S, Nishioka M, Ogawa E,Nakano Y, Hoshino Y, Ito Y, Matsumoto H,Niimi A, Mio T, Chin K, Muro S, Mishima M.
- Journal Title
  
  Respirology 13(3)
  
  Pages: 372-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] TGFB1 promoter polymorphism C-509T andpathophysiology of asthma2008
- Author(s)
  Ueda T, Niimi A, Matsumoto H, Takemura M, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Minakuchi M, Cheng L, Shirakawa T, Mishima M.
- Journal Title
  
  J Allergy ClinImmunol 121(3)
  
  Pages: 659-64
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Redox-based therapeutics for lung diseases.2008
- Author(s)
  Hoshino Y, Mishima M.
- Journal Title
  
  Antioxid Redox Signal. 10(4)
  
  Pages: 701-4
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-l ameliorates cigarette smoke-induced lung inflammation and emphysema2008
- Author(s)
  Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J
- Journal Title
  
  J Pharmacol Exp Ther. 325(2)
  
  Pages: 380-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Sputum levels of transforming growth factor-betal in asthma : relation to clinical and computed tomography findings.2008
- Author(s)
  Yamaguchi M, Niimi A, Matsumoto H, Ueda T, Takemura M, Matsuoka H, Jinnai M, Otsuka K, Oguma T, Takeda T, Ito I, Chin K, Mishima M.
- Journal Title
  
  J Investig Allergol Clin Immunol. 18(3)
  
  Pages: 202-6
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice2008
- Author(s)
  Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J
- Journal Title
  
  J Pharmacol Exp Ther 325(2)
  
  Pages: 380-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Gastroesophagealreflux-associated chronic cough in an adolescentand the diagnostic implications : a case report2008
- Author(s)
  Jinnai M, Niimi A, Takemura M, Matsumoto H,Konda Y, Mishima M.
- Journal Title
  
  Cough 15
  
  Pages: 5-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography.2008
- Author(s)
  Ohara T, Hirai T, Sato S, Terada K, Kinose D, Haruna A, Marumo S, Nishioka M, Ogawa E, Nakano Y, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Muro S, Mishima M.
- Journal Title
  
  Respirology. 13(3)
  
  Pages: 372-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Antimicrobial susceptibilities of Streptococcus pneumoniae isolated from adult patients with community-acquired pneumonia in Japan.2008
- Author(s)
  Ishida T, Maniwa K, Kagioka H, Hirabayashi M, Onaru K, Tomioka H, Hayashi M, Tomii K, Gohma I, Ito Y, Hirai T, Ito I, Mishima M.
- Journal Title
  
  Respirology 13
  
  Pages: 240-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Impact of gastro-oesophageal reflux disease symptoms on COPD exacerbation.2008
- Author(s)
  Terada K, Muro S, Sato S, Ohara T, Haruna A, Marumo S, Kinose D, Ogawa E, Hoshino Y, Niimi A, Terada T, Mishima M.
- Journal Title
  
  Thorax 63(11)
  
  Pages: 951-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography2008
- Author(s)
  Ohara, T., Hirai, T., Sato, S., Terada, K., Kinose, D., Haruna, A., Marumo, S., Nishioka, M., Ogawa, E., Nakano, Y., Hoshino, Y., Ito, Y., Matsumoto, H., Niimi, A., Mio, T., Chin, K., Muro, S., Mishima, M
- Journal Title
  
  Respirology 13(3)
  
  Pages: 372-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Plasma thioredoxin, a novel oxidative stress marker, in patients with obstructive sleep apnea before and after nasal continuous positive airway pressure.2008
- Author(s)
  Takahashi K, Chin K, Nakamura H, Morita S, Sumi K, Oga T, Matsumoto H, Niimi A, Fukuhara S, Yodoi J, Mishima M.
- Journal Title
  
  Antioxid Redox Signal. 10(4)
  
  Pages: 715-26
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Impact ofgastro-oesophageal reflux disease symptoms onCOPD exacerbation2008
- Author(s)
  Terada K, Muro S, Sato S, Ohara T, Haruna A,Marumo S, Kinose D, Ogawa E, Hoshino Y,Niimi A, Terada T, Mishima M
- Journal Title
  
  Thorax 63(11)
  
  Pages: 951-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysemain mice2008
- Author(s)
  Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J.
- Journal Title
  
  J Pharmacol Exp Ther. 325(2)
  
  Pages: 380-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice2008
- Author(s)
  Sato, A., Hoshino, Y., Ham, T., Muro, S., Nakamura, H., Mishima, M., Yodoi, J
- Journal Title
  
  J Pharmlacol Exp Tiler 325(2)
  
  Pages: 380-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Relationship between pulmonary empliysema and osteoporosis assessed by CT in patients with COPD.2008
- Author(s)
  Ohara T, Hirai T, Muro S, Haruna A, Terada K, Kinose D, Marumo S, Ogawa E, Hoshino Y, Niimi A, Chin K, Mishima M.
- Journal Title
  
  Chest 134(6)
  
  Pages: 1244-9
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Redox-basedtherapeutics for lung diseases2008
- Author(s)
  Hoshino Y, Mishima M
- Journal Title
  
  Antioxid Redox Signal 10(4)
  
  Pages: 701-4
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Sputum levels of transforming growth factor-beta1 in asthma : relation to clinical and computed tomography findings2008
- Author(s)
  Yamaguchi M, Niimi A, Matsumoto H, UedaT, Takemura M, Matsuoka H, Jinnai M, OtsukaK, Oguma T, Takeda T, Ito I, Chin K, MishimaM
- Journal Title
  
  J Investig Allergol Clin Immunol 18(3)
  
  Pages: 202-6
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography.2008
- Author(s)
  Ohara T, Hirai T. Sato S. Terada K. Kinose D. Haruna A, Marumo S. Nishioka M. Ogawa E. Nakano Y. Hoshino Y. Ito Y. Matsumoto H. Niimi A. Mio T, Chin K. Muro S, Mishima M.
- Journal Title
  
  Respirology 13(3)
  
  Pages: 372-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Impact of gastro-oesophageal reflux disease symptoms on chronic obstructive pulmonary disease exacerbation2008
- Author(s)
  Kunihiko Terada, Shigeo Muro, Susumu Sato, Tadashi Ohara, Akane Haruna, Satoshi Marumo, Daisuke Kinose, Emiko Ogawa, Yuma Hoshino, Akio Niimi, Tadayuki Terada, and Michiaki Mishima
- Journal Title
  
  Thorax
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Molecular characteristics of serotype 3 Streptococcus pneumoniae isolates among community-acquired pneumonia patients in Japan.2008
- Author(s)
  Isozumi R, Ito Y, Ishida T, Hirai T, Ito I, Maniwa K, Hayashi M, Kagioka H, Hirabayashi M, Onaru K, Tomioka H, Tomii K, Gohma I, Osawa M, Imai S, Takakura S, Iinuma Y, Chin K, Ichiyama S, Mishima M ; the Kansai Community Acquired Pneumococcal Pneumonia Study Group.
- Journal Title
  
  J Infect Chemother 14
  
  Pages: 258-61
- NAID
  10022595304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590896
[Journal Article] Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography.2008
- Author(s)
  Ohara T, Hirai T, Sato S, Terada K, Kinose D, Haruna A, Marumo S, Nishioka M, Ogawa E, Nakano Y, Hoshino Y, Ito Y, Matsumoto H, Niimi A, Mio T, Chin K, Muro S, Mishima M.
- Journal Title
  
  Respirology 13(3)
  
  Pages: 372-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Relationship between pulmonary emphysema and osteoporosis assessed by CT in patients with COPD2008
- Author(s)
  Ohara T, Hirai T, Muro S, Haruna A, Terada K,Kinose D, Marumo S, Ogawa E, Hoshino Y,Niimi A, Chin K, Mishima M.
- Journal Title
  
  Chest 134(6)
  
  Pages: 1244-9
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Morphological mechanism of the development ofpulmonary emphysema in klotho mice2007
- Author(s)
  Sato A, Hirai T, Imura A, Kita N, Iwano A,Muro S, Nabeshima Y, Suki B,Mishima M.
- Journal Title
  
  Proc NatlAcad Sci USA 104(7)
  
  Pages: 2361-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Atopic features of cough variantasthma and classic asthma with wheezing2007
- Author(s)
  Takemura M, Niimi A, Matsumoto H, Ueda T, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Mishima M.
- Journal Title
  
  ClinExp Allergy 37(12)
  
  Pages: 1833-9
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Analysis of longitudinal changes in the psychological status of patients with asthma.2007
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Mishima M.
- Journal Title
  
  Respir Med. 101(10)
  
  Pages: 2133-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Prevalence and clinical manifestations of gastro-oesophageal reflux-associated chronic cough in the Japanese population2007
- Author(s)
  Matsumoto H, Niimi A, Takemura M, Ueda T,Yamaguchi M, Matsuoka H, Jinnai M, Chin K,Mishima M.
- Journal Title
  
  Cough
  
  Pages: 3-1
- NAID
  120004770220
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Neurotropin demonstrates cytoprotective effects in lung cells through the induction of thioredoxin-1.2007
- Author(s)
  Hoshino Y, Nakamura T, Sato A, Mishima M, Yodoi J, Nakamura H.
- Journal Title
  
  Am J Respir Cell Mol Biol. 37(4)
  
  Pages: 438-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Morphological mechanism of the development of pulmonary emphysema in klotho mice.2007
- Author(s)
  Sato A, Hirai T, Imura A, Kita N, Iwano A, Muro S, Nabeshima Y, Suki B, Mishima M
- Journal Title
  
  Proc Natl Acad Sci U S A. Feb 13;104 (7)
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Atopic features of cough variant asthma and classic asthma with wheezing2007
- Author(s)
  Takemura M, Niimi A, Matsumoto H, Ueda T, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Mishima M.
- Journal Title
  
  Clin Exp Allergy. 37(12)
  
  Pages: 1833-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Corticosteroid-induced myopathy mimickingtherapy-resistant asthma2007
- Author(s)
  Yamaguchi M, Niimi A, Minakuchi M,Matsumoto H, Shimizu K, Chin K, Mishima M.
- Journal Title
  
  Ann Allergy AsthmaImmunol 99(4)
  
  Pages: 371-4
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Elevation of serum thioredoxin in patients with gefitinib-induced interstitial lung disease.2007
- Author(s)
  Sakuma K, Nakamura H, Nakamura T, Hoshino Y, Ueda S, Ichikawa M, Tabata C, Fujita S, Masago K, Yodoi J, Mishima M, Mio T.
- Journal Title
  
  Intern Med. 46(23)
  
  Pages: 1905-9
- NAID
  130000078603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Longitudinal deteriorations in patient reported outcomes inpatients with COPD2007
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S,Hajiro T, Mishima M.
- Journal Title
  
  Respir Med 101(1)
  
  Pages: 146-53
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Analysis of longitudinalchanges in the psychological status of patientswith asthma2007
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S,Hajiro T, Mishima M
- Journal Title
  
  Respir Med 101(10)
  
  Pages: 2133-8
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Airway wallthickening in patients with cough variant asthmaand nonasthmatic chronic cough2007
- Author(s)
  Matsumoto H, Niimi A, Tabuena RP,Takemura M, Ueda T, Yamaguchi M, MatsuokaH, Jinnai M, Chin K, Mishima M.
- Journal Title
  
  Chest 131(4)
  
  Pages: 1042-9
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Neurotropin demonstrates cytoprotective effects in lung cells through the induction of thioredoxin-12007
- Author(s)
  Hoshino Y, Nakamura T, Sato A, Mishima M,Yodoi J, Nakamura H
- Journal Title
  
  Am J Respir Cell MolBiol 37(4)
  
  Pages: 438-46
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Morphological mechanism of the development of pulmonary emphysema in klotho mice2007
- Author(s)
  Sato, A., Hirai, T., Imura, A., Kita, N., Iwano, A., Muro, S., Nabeshima, Y., Suki, B., Mishima, M
- Journal Title
  
  Proc Nat : Acad Sci USA 104
  
  Pages: 2361-2365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Corticosteroid-induced myopathy mimicking therapy-resistant asthma.2007
- Author(s)
  Yamaguchi M, Niimi A, Minakuchi M, Matsumoto H, Shimizu K, Chin K, Mishima M.
- Journal Title
  
  Ann Allergy Asthma Immunol. 99(4)
  
  Pages: 371-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Prognosis of cough variant asthma : a retrospective analysis2006
- Author(s)
  Matsumoto, H., Niimi, A., Takemura, M., Ueda, T., Tabuena, R., Yamaguchi, M., Matsuoka, H., Hirai, T., Muro, S., Ito, Y., Mio, T., Chin, K., Nishiyama, H., Mishima, M
- Journal Title
  
  J Asthma 2006 43
  
  Pages: 131-135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Role of small airways in asthma : investigation using high-resolution computed tomography2006
- Author(s)
  Ueda, T., Niimi, A., Matsumoto, H., Takemura, M., Hirai, T., Yamaguchi, M., Matsuoka, H., Jinnai, M., Muro, S., Chin, K., Mishima, M
- Journal Title
  
  J Allergy Clin Immunol 118
  
  Pages: 1019-1025
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] COPDの病態解析と治療法開発・治療評価への挑戦 CT画像解析・チオレドキシン創薬・アウトカムスタディを通して.2006
- Author(s)
  三嶋理晃、中野恭幸、西村浩一、室繁郎, 他
- Journal Title
  
  最新医学 61
  
  Pages: 118-175
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Thioredoxin-1 suppresses systemic inflammatory responses against cigarette smoking2006
- Author(s)
  Sato A, Hara T, Nakamura H, Kato N, Hoshino Y, Kondo N, Mishima M, Yodoi J.
- Journal Title
  
  Antioxid Redox Signal 8(9-10)
  
  Pages: 1891-6
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Role of small airways in asthma : investigation using high-resolution computed tomography2006
- Author(s)
  Ueda T, Niimi A, Matsumoto H, Takemura M, Hirai T, Yamaguchi M, Matsuoka H, Jinnai M, Muro S, Chin K, Mishima M.
- Journal Title
  
  J Allergy Clin Immunol 118(5)
  
  Pages: 1019-25
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Comparison of airway dimensions in different anatomic locations on chest CT in patients with COPD2006
- Author(s)
  Ohara, T., Hirai, T., Sato, S., Sato, A., Nishioka, M., Muro, S., Mishima, M
- Journal Title
  
  Respirology 11
  
  Pages: 579-585
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Comparison of airway dimensions in different anatomic locations on chest CT in patients with COPD.2006
- Author(s)
  Ohara T, Hirai T, Sato S, Sato A, Nishioka M, Muro S, Mishima M
- Journal Title
  
  Respirology Sep;11 (5)
  
  Pages: 579-585
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Role of small airways in asthma : Investigation using high-resolution computed tomography.2006
- Author(s)
  Ueda T, Niimi A, Matsumoto H, Takemura M, Hirai T, Yamaguchi M, Matsuoka H, Jinnai M, Muro S, Chin K, Mishima M
- Journal Title
  
  J Allergy Clin Immunol 118
  
  Pages: 1019-1025
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] High sensitivity C-reactive protein in asthma2006
- Author(s)
  Takemura, M., Matsumoto, H., Niimi, A., Ueda, T., Matsuoka, H., Yamaguchi, M., Jinnai, M., Mum, S., Hirai, T., Ito, Y., Nakamura, T., Mio, T., Chin, K., Mishima, M
- Journal Title
  
  Eur Respir J 27
  
  Pages: 908-912
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] High sensitivity C-reactive protein in asthma2006
- Author(s)
  Takemura M, Matsumoto H, Niimi A, Ueda T, Matsuoka H, Yamaguchi M, Jinnai M, Muro S,Hirai T, Ito Y, Nakamura T, Mio T, Chin K, Mishima M.
- Journal Title
  
  Eur Respir J 27(5)
  
  Pages: 908-12
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] -CT画像解析・チオレドキシン創薬・アウトカムスタディを通して-第42回(2005年度)エルウィン・フォン・ベルツ賞1等賞受賞論文2006
- Author(s)
  三嶋理晃, 中野恭幸, 西村浩一, 新実彰男, 平井豊博, 室繁郎, 小賀徹, 星野勇馬, 中村肇, 淀井淳司
- Journal Title
  
  最新医学 (掲載予定)
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Comparison of airway dimensions in different anatomic locations on chest CT in patients with COPD.2006
- Author(s)
  Ohara T, Hirai T, Sato S, Sato A, Nishioka M, Muro S, Mishima M
- Journal Title
  
  Respirology 11
  
  Pages: 579-585
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Comparison of airway dimensions in different anatomic locations on chest CT in patients with COPD2006
- Author(s)
  Ohara T, Hirai T, Sato S, Sato A, Nishioka M, Muro S, Mishima M
- Journal Title
  
  Respirology 11(5)
  
  Pages: 579-85
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Prognosis of cough variant asthma : a retrospective analysis.2006
- Author(s)
  Motsumoto, H., A.Niimi, M.Takemura, T.Ueda, R.Tabuena, M.Yamaguchi, H.Matsuoka, T.Hirai, S.Muro, Y.Ito, T.Mio, K.Chin, H.Nishiyama, M.Mishima
- Journal Title
  
  J Asthma 43 (2)
  
  Pages: 131-135
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Dyspnoea with activities of dailyliving versus peak dyspnoea during exercise in male patients with COPD2006
- Author(s)
  Oga T, Nishimura K, Tsukino M, Hajiro T, Mishima M.
- Journal Title
  
  Respir Med 100(6)
  
  Pages: 965-71
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Thioredoxin-l suppresses systemic inflammatory responses against cigarette smoking.2006
- Author(s)
  Sato A, Hara T, Nakamura H, Kato N, Hoshino Y, Kondo N, Mishima M
- Journal Title
  
  Antioxid Redox Signal 8 (9-10)
  
  Pages: 1891-1896
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Airway dimensions of the basal segment bronchi in patients with chronic obstructive pulmonary disease.2006
- Author(s)
  Nishioka M, Sato A, Ogawa E, Muro S, Mishima M
- Journal Title
  
  Respirology A10(in press)
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Prognosis of cough variant asthma : a retrospective analysis2006
- Author(s)
  Matsumoto H, Niimi A, Takemura M, Ueda T, Tabuena R, Yamaguchi M, Matsuoka H, Hirai T, Muro S, Ito Y, Mio T, Chin K, Nishiyama H, Mishima M.
- Journal Title
  
  J Asthma 43(2)
  
  Pages: 131-5
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma2005
- Author(s)
  Matsumoto H, Niimi A, Takemura M, Ueda T, Minakuchi M, Tabuena R, Chin K, Mio T, lto Y, Muro S, Hirai T, Morita S, Fukuhara S, Mishima M
- Journal Title
  
  Thorax 60(4)
  
  Pages: 277-81
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema2005
- Author(s)
  Ito, I., Nagai, S., Handa, T., Muro, S., Hirai, T., Tsukino, M., Mishima, M
- Journal Title
  
  Am J Respir Crit Care Med 172
  
  Pages: 1378-1382
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema.2005
- Author(s)
  Ito I, Nagai S, Handa T, Muro S, Hirai T, Tsukino M, Mishima M
- Journal Title
  
  Am J Respir Crit Care Med. Dec1;172(11)
  
  Pages: 1378-1382
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma2005
- Author(s)
  Matsumoto, H., Niimi, A., Takemura, M., Ueda, T., Minakuchi, M., Tabuena, R., Chin, K., Mio, T., Ito, Y., Muro, S., Hirai, T., Morita, S., Fukuhara, S., Mishima, M
- Journal Title
  
  CERNED,YEAR Thorax 60
  
  Pages: 277-281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma.2005
- Author(s)
  Matsumoto H, Niimi A, Takemura M, Ueda T, Minakuchi M, Tabuena R, Chin K, Mio T, Ito Y, Muro S, Hirai T, Morita S, Fukuhara S, Mishima M.
- Journal Title
  
  Thorax Apr;60(4)
  
  Pages: 277-281
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Exercise capacity deterioration in patients with COPD : longitudinal evaluation over 5 years2005
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Mishima M
- Journal Title
  
  Chest. 128(1)
  
  Pages: 62-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema2005
- Author(s)
  Ito I, Nagai S, Handa T, Muro S, Hirai T, Tsukino M, Mishima M
- Journal Title
  
  Am J Respir Crit Care Med 172(11)
  
  Pages: 1378-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma2005
- Author(s)
  Matsumoto H, Niimi A, Takemura M, Ueda T, Minakuchi M, Tabuena R, Chin K, Mio T, Ito Y, Muro S, Hirai T, Morita S, Fukuhara S, Mishima M.
- Journal Title
  
  Thorax. 60(4)
  
  Pages: 277-281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Exercise capacity deterioration in patients with COPD : longitudinal evaluation over 5 years2005
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Mishima M.
- Journal Title
  
  Chest 128(1)
  
  Pages: 62-69
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema2005
- Author(s)
  Ito I, Nagai S, Handa T, Muro S, Hirai T, Tsukino M, Mishima M.
- Journal Title
  
  Am J Respir Crit Care Med. 172(11)
  
  Pages: 1378-1382
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Possible maximal change in the SF-36 of outpatients with chronic obstructive pulmonary disease and asthma2004
- Author(s)
  Sato S, Nishimura K, Tsukino M, 0ga T, Hajiro T, lkeda A, Mishima M
- Journal Title
  
  Am J Med. 116(11)
  
  Pages: 725-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Effect of short-term treatment with inhaled corticosteroid on airway wall thickening in asthma.2004
- Author(s)
  Niimi A, Matsumoto H, Amitani R, Nakano Y, Sakai H, Takemura M, Ueda T, Chin K, Itoh H, Ingenito EP, Mishima M.
- Journal Title
  
  Am J Med. 116(11)
  
  Pages: 725-731
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele.2004
- Author(s)
  Mishima M, Ito I, Nagai S, Hoshino Y, Muro S, Hirai T.
- Journal Title
  
  Chest. 125(1)
  
  Pages: 63-70
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Longitudinal changes in health status using the chronic respiratory disease questionnaire and pulmonary function in patients with stable chronic obstructive pulmonary disease.2004
- Author(s)
  Oga T, Nishimura K, Tsukino M, Hajiro T, Sato S, Ikeda A, Hamadas C, Mishima M.
- Journal Title
  
  Qual Life Res. 13(6)
  
  Pages: 1109-1116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele.2004
- Author(s)
  Ito I, Nagai S, Hoshino Y, Muro S, Hirai T, Tsukino M, Mishima M.
- Journal Title
  
  Chest. 125(1)
  
  Pages: 63-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Longitudinal changes in health status using the chronic respiratory disease questionnaire and pulmonary function in patients2004
- Author(s)
  Mishima M, Oga T, Nishimura K, Tsukino M.
- Journal Title
  
  Qual Life Res. 13(6)
  
  Pages: 1109-1116
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Longitudinal changes in health status using the chronic respiratory disease questionnaire and pulmonary function in patients with stable chronic obstructive pulmonary disease2004
- Author(s)
  Oga T, Nishimura K, Tsukino M, Hajiro T, Sato S, Ikeda A, Hamada C, Mishima M
- Journal Title
  
  Qual Life Res 13(6)
  
  Pages: 1109-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Possible maximal change in the SF-36 of outpatients with chronic obstructive pulmonary disease and asthma.2004
- Author(s)
  Sato S, Nishimura K, Tsukino M, Oga T, Hajiro T, Ikeda A, Mishima M.
- Journal Title
  
  J Asrhma. 41(3)
  
  Pages: 355-365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Possible maximal change in the SF-36 of outpatients with chronic obstructive pulmonary disease and asthma.2004
- Author(s)
  Mishima M, Sato S, Nishimura K, Tsukino M, Oga T.
- Journal Title
  
  J Asthma. 41(3)
  
  Pages: 355-365
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Effect of short-term treatment with inhaled corticosteroid on airway wall thickening in asthma.2004
- Author(s)
  Mishima M, Niimi A, Matsumoto H, Amitani R, Nakano Y.
- Journal Title
  
  Am J Med. 116(11)
  
  Pages: 725-731
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Bronchial dilatation in asthma : relation to clinical and sputum indices.2004
- Author(s)
  Mishima M, Takemura M, Niimi A, Minakuchi M, Matsumoto H
- Journal Title
  
  Chest. 125(4)
  
  Pages: 1352-1358
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] A comparison of the effects of salbutamol and ipratropium bromide on exercise endurance in patients with COPD.2003
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Mishima M.
- Journal Title
  
  Chest. 123(6)
  
  Pages: 1810-1816
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Chronic eosinophilic pneumonia : treatment with inhaled corticosteroids.2003
- Author(s)
  Minakuchi M, Niimi A, Matsumoto H, Amitani R, Mishima M.
- Journal Title
  
  Respiration. 70(4)
  
  Pages: 362-366
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Complexity of terminal airspace geometry assessed by computed tomography in asthma.2003
- Author(s)
  Mitsunobu F, Ashida K, Hosaki Y, Tsugeno H, Okamoto M, Nishida K, Takata S, Yokoi T, Mishima M, Tanizaki Y.
- Journal Title
  
  Am J Respir Crit Care Med. 167(3)
  
  Pages: 411-417
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Optimal cutoff level of breach carbon monoxide for assessing smoking status in patients with asthma and COPD.2003
- Author(s)
  Sato S, Nishimura K, Koyama H, Tsukino M, Oga T, Hajiro T, Mishima M.
- Journal Title
  
  Chest. 124(5)
  
  Pages: 1749-1754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Relationship of airway wall thickness to airway sensitivity and airway reactivity in asthma2003
- Author(s)
  Niimi A, Matsumoto H, Takemura M, Ueda T, Chin K, Mishima M.
- Journal Title
  
  Am J Respir Crit Care Med 15;168(8)
  
  Pages: 983-988
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] A comparison of the responsiveness of different generic health status measures in patients with asthma2003
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Mishima M.
- Journal Title
  
  Qual Life Res. 12(5)
  
  Pages: 555-563
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Comparison of the responsiveness of different disease-specific health status measures in patients with asthma.2002
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Mishima M.
- Journal Title
  
  Chest. 122(4)
  
  Pages: 1228-1233
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Longitudinal changes in airflow limitation and airway hyperresponsiveness in patients with stable asthma2002
- Author(s)
  Oga T, Nishimura K, Tsukino M, Hajiro T, Sato S, Ikeda A, Hamada C, Mishima M.
- Journal Title
  
  Ann Allergy Asthma Immunol. 89(6)
  
  Pages: 619-625
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Relationship between different indices of exercise capacity and clinical measures in patients with chronic obstructive pulmonary disease.2002
- Author(s)
  Oga T, Nishimura K, Tsukino M, Hajiro T, Ikeda A, Mishima M.
- Journal Title
  
  Heart Lung. 31(5)
  
  Pages: 374-381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] Health status measured with the CRQ does not predict mortality in COPD.2002
- Author(s)
  Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Ikeda A, Mishima M.
- Journal Title
  
  Eur Respir J. 20(5)
  
  Pages: 1147-1151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557050
[Journal Article] M. Airway wall thickening in patients with cough variant asthma and nonasthmatic chronic cough.
- Author(s)
  Matsumoto H, Niimi A, Tabuena RP, Takemura M, Ueda T, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Mishima
- Journal Title
  
  Chest (in press)
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Impact of gastro-oesophageal reflux disease symptoms on chronic obstructive pulmonary disease exacerbation.
- Author(s)
  Kunihiko Terada, Shigeo Muro, Susumu Sato, Tadashi Ohara, Akane Haruna, Satoshi Marumo, Daisuke Kinose, Emiko Ogawa, Yuma Hoshino, Akio Niimi, Michiaki Mishima.
- Journal Title
  
  Thorax (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Effect of inhaled corticosteroidson small airways in asthma: Investigation usingimpulse oscillometry
- Author(s)
  Yamaguchi M, Niimi A, Ueda T, TakemuraM, Matsuoka H, Jinnai M, Otsuka K, Oguma T,Takeda T, Ito I, Matsumoto H, Hirai T, Chin K,Mishima M.
- Journal Title
  
  Pulm Pharmacol Ther (in press)
- Data Source
  KAKENHI-PROJECT-18209029
[Journal Article] Impact of gastro-oesophageal reflux disease symptoms on chronic obstructive pulmonary disease exacerbation
- Author(s)
  Terada, K., Muro, S., Sato, S., Ohara, T., Haruna, A., Marumo, S, Kinose, D., Ogawa, E., Hoshino, Y., Niimi, A., Terada, T., Mishima, M
- Journal Title
  
  Thorax (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Journal Article] Cough-ReflexSensitivity to Inhaled Capsaicin in ChronicObstructive Pulmonary Disease : the Impact onExacerbation Frequency
- Author(s)
  Kunihiko Terada, M.D., Shigeo Muro, M.D.,Ph. D., Tadashi Ohara, M.D., Ph. D., AkaneHaruna, M.D., Satoshi Marumo, M.D., MegumiKudo, M.D., Emiko Ogawa, M.D., Ph. D.,Yuma Hoshino, M.D., Ph. D., Toyohiro Hirai,M.D., Ph. D., Akio Niimi, M.D., Ph. D.,Michiaki Mishima, M.D., Ph. D.
- Journal Title
  
  Respirology (in press)
- Data Source
  KAKENHI-PROJECT-18209029
[Patent] 肺胞上皮前駆細胞の誘導方法2014
- Inventor(s)
  長船健二/後藤慎平/伊藤功朗/三嶋理晃
- Industrial Property Rights Holder
  長船健二/後藤慎平/伊藤功朗/三嶋理晃
- Industrial Property Rights Type
  特許
- Filing Date
  2014-04-14
- Overseas
- Data Source
  KAKENHI-PROJECT-26293199
[Patent] 肺胞上皮前駆細胞の誘導方法2014
- Inventor(s)
  長船健二/後藤慎平/伊藤功朗/三嶋理晃
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-04-14
- Overseas
- Data Source
  KAKENHI-PROJECT-22249031
[Patent] 肺胞上皮前駆細胞の誘導方法2013
- Inventor(s)
  長船健二, 後藤慎平, 伊藤功朗, 三嶋理晃
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Number
  2013-084034
- Filing Date
  2013-04-12
- Overseas
- Data Source
  KAKENHI-PROJECT-23591146
[Patent] 肺胞上皮前駆細胞の誘導2013
- Inventor(s)
  長船健二、後藤慎平、伊藤功朗、三嶋理晃
- Industrial Property Rights Holder
  国立大学法人　京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-04-12
- Data Source
  KAKENHI-PROJECT-22249031
[Patent] 肺胞上皮前駆細胞の誘導2013
- Inventor(s)
  長船健二、後藤慎平、伊藤功朗、三嶋理晃
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-084034
- Filing Date
  2013-04-19
- Data Source
  KAKENHI-PROJECT-23591146
[Presentation] Long-term expansion of alveolar stem cells derived from human iPS cells by forming organoids2017
- Author(s)
  山本佑樹、後藤慎平、興梠陽平、関真秀、小西聡史、池尾聡、曽根尚之、長崎忠雄、松本久子、室繁郎、伊藤功朗、平井豊博、河野隆志、鈴木穣、三嶋理晃
- Organizer
  CiRA 2017 International Symposium
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] ヒトiPS細胞から機能的な気道線毛上皮細胞への分化誘導2016
- Author(s)
  小西聡史、後藤慎平、立石和博、山本佑樹、興梠陽平、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、月田早智子、三嶋理晃
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] Long-term culture of alveolar epithelial type 2 cells derived from human induced pluripotent stem cells.2016
- Author(s)
  山本佑樹、後藤慎平、興梠陽平、小西聡史、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、三嶋理晃
- Organizer
  International Society for Stem Cell Research 14th Annual Meeting
- Place of Presentation
  Samfrancisco, USA
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] ヒトiPS細胞から気道繊毛上皮前駆細胞への効率の良い分化誘導法の確立2015
- Author(s)
  小西聡史、後藤慎平、山本佑樹、興梠陽平、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、三嶋理晃
- Organizer
  第55回日本呼吸器学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] ヒトiPS細胞から気道線毛上皮細胞への分化誘導2015
- Author(s)
  小西聡史、後藤慎平、立石和博、山本佑樹、興梠陽平、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、月田早智子、三嶋理晃
- Organizer
  第38回　日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] 遺伝性呼吸器疾患の疾患特異的iPS細胞樹立2015
- Author(s)
  後藤慎平、伊藤功朗、興梠陽平、山本佑樹、小西聡史、長崎忠雄、松本久子、佐藤篤靖、室繁郎、平井豊博、長船健二、浅香勲、瀬山邦明、三嶋理晃
- Organizer
  第55回日本呼吸器学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] Generation of ciliated airway epithelial cells from human induced pluripotent stem cells2015
- Author(s)
  小西聡史、後藤慎平、山本佑樹、興梠陽平、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、三嶋理晃
- Organizer
  ISSCR 2015 annual meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] ヒトiPS細胞からⅡ型肺胞上皮細胞への分化誘導効率の改善2015
- Author(s)
  山本佑樹、後藤慎平、興梠陽平、小西聡史、長崎忠雄、松本久子、室繁郎、平井豊博、伊藤功朗、三嶋理晃
- Organizer
  第55回日本呼吸器学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] ヒト多能性幹細胞から呼吸器上皮細胞への分化誘導2015
- Author(s)
  後藤慎平、伊藤功朗、興梠陽平、山本佑樹、小西聡史、長崎忠雄、松本久子、佐藤篤靖、室繁郎、平井豊博、長船健二、浅香勲、瀬山邦明、三嶋理晃
- Organizer
  第15回　日本細胞生物学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] 無治療肺Mycobacterium avium complex症患者における菌陰性化と環境暴露との関係2013
- Author(s)
  伊藤　穣、平井豊博、藤田浩平、前川晃一、久保　武、富樫かおり、一山　智、三嶋理晃
- Organizer
  第88回日本結核病学会総会
- Place of Presentation
  幕張、千葉
- Data Source
  KAKENHI-PROJECT-24591479
[Presentation] Influence of environmental exposures on sputum culture conversion in untreated pulmonary Mycobacterium avium-intracellulare complex disease2013
- Author(s)
  Yutaka Ito, Toyohiro Hirai, Kohei Fujita, Koichi Maekawa, Takeshi kubo,Kaori Togashi, Satoshi Ichiyama Michiaki Mishima
- Organizer
  American Thoracic Society 2013 international conference
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-24591479
[Presentation] Association of polyclonal Mycobacterium avium-intracellulare complex (MAC) infection with environmental exposure in patients with pulmonary MAC disease2013
- Author(s)
  Fujita K, Ito Y, Hirai T, Maekawa K, Kubo T,Togashi K, Ichiyama S, Mishima M.
- Organizer
  ATS 2013 internatinal conference
- Place of Presentation
  フィラデルフィア、ペンシルベニアコンベンションセンター
- Data Source
  KAKENHI-PROJECT-24591479
[Presentation] 肺Mycobacterium avium complex(MAC)症治療の有効性に対する環境暴露の影響2013
- Author(s)
  伊藤　穣、平井豊博、藤田浩平、前川晃一、久保　武、富樫かおり、一山　智、三嶋理晃
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591479
[Presentation] Association of polyclonal Mycobacterium avium-intracellulare complex (MAC) infection with environmental exposure in patients with pulmonary MAC disease2013
- Author(s)
  Kohei Fujita, Yutaka Ito, Toyohiro Hirai, Koichi Maekawa, Takeshi kubo,Kaori Togashi, Satoshi Ichiyama Michiaki Mishima
- Organizer
  American Thoracic Society 2013 international conference
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-24591479
[Presentation] Influence of environmental exposureon sputum conversion in untreated pulmonary Mycobacterium avium-intracellulare complex disease2013
- Author(s)
  Ito Y, Fujita K,Hirai T, Maekawa K, Kubo T, Togashi K, Ichiyama S, Mishima M.
- Organizer
  ATS 2013 internatinal conference
- Place of Presentation
  フィラデルフィア、ペンシルベニアコンベンションセンター
- Data Source
  KAKENHI-PROJECT-24591479
[Presentation] 肺Mycobacterium avium-intracellulare complex(MAC)症におけるMAC多クローン菌感染と環境暴露の関連2013
- Author(s)
  藤田浩平、伊藤　穣、平井豊博、前川晃一、久保　武、富樫かおり、一山　智、三嶋理晃
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京、東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24591479
[Presentation] Correlation of Vascular Endothelial Growth Factor Receptor 2 With Pulmonary Function And Emphysematous Change In Early Chronic Obstructive Pulmonary Disease2012
- Author(s)
  T. Takahashi, E. Ogawa, A. Haruna, M. Kudo, H. Kiyokawa, N. Tanabe, D. Kinose, S. Sato, Y. Hoshino, T. Hirai, H. Sakai, Y. Nakano, S. Muro, M. Mishima
- Organizer
  American Thoracic Society Poster Session
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2012-05-22
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Clinical problems in COPD2012
- Author(s)
  三嶋理晃
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-22249031
[Presentation] Annual Changes Of "Lung Age". Validation Of Lung Age Equation By 5-Year Follow Up Study In Japan2012
- Author(s)
  S. Sato, S. Muro, T. Takahashi, T. Hirai, M. Mishima, A. Sato
- Organizer
  American Thoracic Society Poster Session
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Influence of environmental exposures on treatment outcomes in pulmonary Mycobacterium avium-intracellulare complex disease2012
- Author(s)
  Yutaka Ito, Toyohiro Hirai, Kohei Fujita, Koichi Maekawa, Seiichiro Imai, Michiaki Mishima
- Organizer
  IDWeek meeting 2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24591479
[Presentation] Increased TLR3 Gene Expression In Epithelial Cells Of COPD Patients/D. Kinose2012
- Author(s)
  E. Ogawa, S. Muro, W. M. Elliott, J. C. Hogg, M. Mishima
- Organizer
  American Thoracic Society Thematic Poster Session
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2012-05-20
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Impact of COPD Exacerbations On Osteoporosis Assessed By Chest CT Scan2012
- Author(s)
  H. Kiyokawa, S. Muro, T. Oguma, S. Sato, N. Tanabe, T. Takahashi, M. Kudo, D. Kinose, Y. Hoshino, E. Ogawa, T. Hirai, M. Mishima
- Organizer
  American Thoracic Society Poster Discussion Session
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2012-05-22
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] 病型分類の臨床的意義2011
- Author(s)
  三嶋理晃
- Organizer
  第51回呼吸器学会総会シンポジウム
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-22249031
[Presentation] Oxidative stress augmented IL-32 gene upregulation in airway epithelial cells2010
- Author(s)
  M. Kudo, MD, E. Ogawa, MD, PhD, A. Haruna, MD, D. Kinose, MD., Y. Hoshino, MD, PhD, S. Muro, MD. PhD., T. Hirai, MD, PhD, M. Mishima, MD, PhD
- Organizer
  American Thoracic Society
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Mechanisms of Enhanced Ca2+ Oscillation Frequency by Interleukin-13 in Airway Smooth Muscle Cells2010
- Author(s)
  H.Matsumoto, Y.Hirata, K.Otsuka, A.Niimi, I.Ito, T.Iwata, E.Ogawa, S.Muro, H.Sakai, K.Chin, Y.Oku, M.Mishima
- Organizer
  ATS2010
- Place of Presentation
  Colorado
- Data Source
  KAKENHI-PROJECT-22249031
[Presentation] The effect of telling smokers their "lung age" on smoking quit rate at annual health checkup2010
- Author(s)
  S. Marumo, MD1, S. Muro, MD. PhD. 1, A. Haruna, MD1, A. Sato, M. D., Ph. D. 2, E. Ogawa, MD, PhD1, Y. Hoshino, MD, PhD1, T. Hirai, MD, PhD1, M. Mishima, MD, PhD1, A. Sato, MD. PhD1
- Organizer
  American Thoracic Society Thematic Poster Session
- Year and Date
  2010-05-17
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] A single nucleotide polymorphism in NOD2 gene was associated with pathogenesis and severity of COPD2010
- Author(s)
  D. Kinose, E. Ogawa, T. Hirota, I. Ito, S. Muro, Y. Hoshino, T. Hirai, H. Sakai, M. Tamari, M. Mishima
- Organizer
  European Respiratory Society Barcelona
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] 血清歯周病抗体価とCOPD(慢性閉塞性肺疾患)増悪との関連性2010
- Author(s)
  高橋珠紀、室繁郎、三嶋理晃
- Organizer
  第75回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Distinct responses against polyinosine-polycytidylic acid in smoke-exposed mouse strains with different susceptibility to emphysema2010
- Author(s)
  N. Tanabe, MD, Y. Hoshino, MD, PhD, H. Kiyokawa, MD, S. Marumo, MD, E. Ogawa, MD, PhD, S. Muro, MD, PhD, T. Hirai, MD, PhD, M. Mishima, MD, PhD
- Organizer
  American Thoracic Society
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Effects of thioredoxin-1 on accelerated emphysema progression in cigarette smoke-exposed mice challenged with polyinosine-polycytidylic acid2010
- Author(s)
  N. Tanabe, Y. Hoshino, H. Kiyokawa, S. Marumo, E. Ogawa, S. Muro, T. Hirai, J. Yodoi, M. Mishima
- Organizer
  European Respiratory Society
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] HRCTを用いた細菌性肺炎と非定型肺炎の鑑別に関するprospective study2009
- Author(s)
  伊藤功朗, 石田直, 橋本徹, 有田真知子, 大澤真, 橘洋正, 新実彰男, 三嶋理晃
- Organizer
  第49回日本呼吸器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590896
[Presentation] Regulation of Connective Tissue Growth Factor Gene Expression by Lipopolysaccharide in Bronchial Epithelial Cells2009
- Author(s)
  M. Nishioka, E. Ogawa, T. Hirai, S. Muro, M. Mishima
- Organizer
  2006 International Conference of American Thoracic Society
- Place of Presentation
  San Diego Convention Center, San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Systemic Immune Activation by Polyinosine-Polycytidylic Acid Evokes Lung Inflammation Similar to COPD Exacerbation in Cigarette Smoke-Exposed Mice2009
- Author(s)
  N. Tanabe, MD, Y. Hoshino, MD, Ph, S. Marumo, MD, I. Ito, MD, Ph, E. Ogawa, MD, Ph, S. Muro, MD, Ph, T. Hirai, MD, Ph, M. Mishima, MD, Ph
- Organizer
  Thematic Poster Session
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] MMP-9プロモータ遺伝子多型は上肺野優位の肺気腫病変と関連する2009
- Author(s)
  伊藤功朗, 長井苑子, 半田知宏, 室繁郎, 平井豊博, 月野光博, 三嶋理晃
- Organizer
  第49回日本呼吸器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590896
[Presentation] 胃食道逆流症症状とCOPD増悪2009
- Author(s)
  D. Kinose, MD, E. Ogawa, MD, PhD, S. Muro, MD, PhD, A. Takahashi, MD, H. Sakai, MD, PhD, W. M. Elliott, PhD, J. C. Hogg, MD, PhD, M. Mishima, MD, PhD
- Organizer
  第14回学術集会
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Pathophysiology of Cigarette Smoke Induced Emphysema after Smoking Cessation in a Murine Model2009
- Author(s)
  MD, A. Sato, MD, PhD, I. Ito, MD, PhD, E. Ogawa, MD, PhD, S. Muro, MD, PhD, T. Hirai, MD, PhD, M. Mishima, MD, PhD
- Organizer
  Mini-Symposium
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Increased NOD1 and NOD2 Gene Expressions in Bronchial Epithelial Cells in COPD2009
- Author(s)
  D. Kinose, MD, E. Ogawa, MD, PhD, S. Muro, MD, PhD, A. Takahashi, MD, H. Sakai, MD, PhD, W. M. Elliott, PhD, J. C. Hogg, MD, PhD, M. Mishima, MD, PhD
- Organizer
  Mini-Symposium
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-21590964
[Presentation] Relation between smallairways and patient reported outcomes in chronic obstructive pulmonary disease2008
- Author(s)
  Akane Haruna, Toru Oga, Shigeo Muro, Tadashi Ohara, Kunihiko Terada, Daisuke Kinose, Satoshi Marumo, Yuma Hoshino, Toyohiro Hirai, Emiko Ogawa, Kazuo Chin, Michiaki Mishima
- Organizer
  2008 International Conference of American ThoracicSociety
- Place of Presentation
  Metro Toronto Convention Centre, Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Impaired swallowing reflex predisposes to COPD exacerbations2008
- Author(s)
  Kunihiko Terada, Shigeo Muro, TadashiOhara, Megumi Kudo, Emiko Ogawa, YumaHoshino, Toyohiro Hirai, Akio Niimi, MichiakiMishima
- Organizer
  18th Annual Conference of European Respiratory Society
- Place of Presentation
  Messe Sud, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Chest Subcutaneous Fat Mass Measured by Chest Computed Tomography Correlated with Low Attenuation Areas in COPD2008
- Author(s)
  E. Ogawa., T. Ohara, Kinose, Nishioka. Sakai, MD, S. Muro, T. Hirai, Y. Nakano, M. Mishima
- Organizer
  2008 International Conference of American Thoracic Society
- Place of Presentation
  MetroToronto Convention Centre, Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Sputum leukocytosis on stable condition predicts chronic obstructive pulmonary disease exacerbations2008
- Author(s)
  Kunihiko Terada, Shigeo Muro, TadashiOhara, Akane Haruna, Satoshi Marumo, Daisuke Kinose, Emiko Ogawa, Yutaka Ito, Satoshi Ichiyama, Michiaki Mishima
- Organizer
  2008 International Conferenceof American Thoracic Society
- Place of Presentation
  Metro Toronto Convention Centre, Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] TNF-alpha Modulates Expressions of MMPs and Migratory Function of Human Airway Smooth Muscle Cells2008
- Author(s)
  Ito I, Hamid Q, Niimi A, Matsumoto H,Yamaguchi M, Matsuoka H, Jinnai M, OtsukaK, Takeda T, Nakaji H, Mishima M
- Organizer
  2008 International Conference of American Thoracic Society
- Place of Presentation
  Metro Toronto Convention Centre, Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Relationship between Small Airways Function, and Health Status, Dyspneaand Disease Control in Asthma2008
- Author(s)
  Takeda T, Oga T, Niimi A, Matsumoto H, Ito I, Yamaguchi M, Matsuoka H, Jinnai M, Otsuka K, Oguma T, Nakaji H, Chin K, Mishima M
- Organizer
  2008 International Conference of American Thoracic Society
- Place of Presentation
  Metro Toronto Convention Centre, Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Corticosteroid Suppressed LPS Induced NOD2 Gene Expression in Airway Epithelial Cells.(Kyoto, Japan)2007
- Author(s)
  D., Kinose, E., Ogawa, M., Nishioka, Y., Hoshino, T., Hirai, S., Muro, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  SanFrancisco American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Thioredoxin Suppressed Cigarette Smoke Induced Emphysema in Mice2007
- Author(s)
  A. Sato, Y. Hoshino, M. Takenaka, S. Muro, H. Nakamura, J. Yodoi, M. Mishima
- Organizer
  American Thoracic Society
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Dynamic Property of Central Airway Walls as Assessed by Computed Tomography (CT) : Correlation with Asthma Pathophysiology.2007
- Author(s)
  Yamaguchi M, Niimi A, Matsumoto H,Ueda T, Takemura M, Matsuoka H, Jinnai M,Mishima M
- Organizer
  2007 International Conference of American Thoracic Society
- Place of Presentation
  Moscone Convention Center, San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Geographic Difference in Chronic Cough Etiology : Comparison of Japan with the UK2007
- Author(s)
  Niimi A, Ueda T, Matsumoto H, Chung KF, Mishima M
- Organizer
  2007 International Conference of American Thoracic Society
- Place of Presentation
  Moscone Convention Center, San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Arterial Hypoxia Correlated with the Inflammatory Profile in Induced Sputum from COPD Patients2007
- Author(s)
  Sato, S. Muro, S. Sato, M. Nishioka, Y. Hoshino, E. Ogawa, T. Hirai, H. Nakamura, J. Yodoi, M. Mishima
- Organizer
  2007 International Conference of American Thoracic Society
- Place of Presentation
  Moscone Convention Center, San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Impacts of gastro-oesophageal reflux symptoms on exacerbations of COPD2007
- Author(s)
  K. Terada, S. Muro, A. Niimi, E. Ogawa, Y. Hoshino, S. Sato, T. Ohara, D. Kinose, A. Haruna, S. Marumo, M. Mishima
- Organizer
  17th Annual Conference of European Respiratory Society
- Place of Presentation
  Stockholm International Fair and Congress Center, Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Corticosteroid Suppressed LPS Induced NOD2 Gene Expression in Airway Epithelial Cells/D2007
- Author(s)
  Kinose, E. Ogawa, M. Nishioka, Y. Hoshino, T. Hirai, S. Muro, M. Mishima
- Organizer
  2007 International Conference of American Thoracic Society
- Place of Presentation
  Moscone Convention Center, San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Thioredoxin Suppressed Cigarette Smoke Induced Emphysema in Mice2007
- Author(s)
  Sato, Y. Hoshino, M. Takenaka, S. Muro, H. Nakamura, J. Yodoi, M. Mishima
- Organizer
  2007 International Conference of American Thoracic Society
- Place of Presentation
  Moscone Convention Center, San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Morphological Mechanism Of The Development Of ulmonary Emphysema In Klotho Mice2007
- Author(s)
  T. HIRAI, A. SATO, S. MURO, A. IMURA, Y. NABESHIMA AND M. MISHIMA
- Organizer
  Biomedical Engineering Symposium
- Place of Presentation
  Losangels, USA.
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Thioredoxin Suppressed Cigarette Smoke Induced Emphysema in Mice2007
- Author(s)
  A., Sato, Y., Hoshino, M., Takenaka, S., Muro, H., Nakamura, J., Yodoi, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  SanFrancisco American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Corticosteroid Suppressed LPS Induced NOD2 Gene Expression in Airway Epithelial Cells2007
- Author(s)
  D. Einose, E. Ogawa, M Nishioka, Y. Hoshino, T. Hirai, S. Muro, M. Mishima
- Organizer
  American Thoracic Society
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Arterial Hypoxia Correlated with the Inflammatory Profile in Induced Sputum from COPD Patients2007
- Author(s)
  A., Sato, S., Mum, S., Sato, M., Nishioka, Y., Hoshino, E., Ogawa, T., Hirai, H., Nakamura, J., Yodoi, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  SanFrancisco American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Arterial Hypoxia Correlated with the Inflammatory Profile in Induced Sputum from COPD Patients2007
- Author(s)
  A Sato, S. Muro, S. Sato, M. Nishioka. Y. Hoshino, E. Ogawa, T. Hirai, H. Nakamura, J. Yodoi, M. Mishima
- Organizer
  American Thoracic Society
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Respiratory Resistance In COPD Patients Using Impulse Oscillometry2007
- Author(s)
  S. SATO, T. HIRAI, S. MURO AND M. MISHIMA
- Organizer
  Biomedical Engineering Symposium
- Place of Presentation
  Losangels, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Thioredoxin Suppressed Cigarette Smoke Induced Emphysema in Mice,2007
- Author(s)
  A. Sato, M. D., Y. Hoshino, M. D., Ph, M. Takenaka, S. Muro, M. D., Ph, H. Nakamura, M. D., Ph, J. Yodoi, M. D., Ph, M. Mishima, M. D.
- Organizer
  American Thoracic Society
- Place of Presentation
  SanFrancisco
- Year and Date
  2007-05-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Corticosteroid Suppressed LPS Induced NOD2 Gene Expression in Airway Epithelial Cells2007
- Author(s)
  D. Kinose, M. D., E. Ogawa, M. D., Ph, M. Nishioka, M. D., Y. Hoshino, M. D., Ph, T. Hirai, M. D., Ph, S. Muro, M. D., Ph, M. Mishima, M. D.,
- Organizer
  American Thoracic Society
- Place of Presentation
  SanFrancisco
- Year and Date
  2007-05-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Impacts of gastro-oesophageal reflux symptoms on exacerbations of COPD2007
- Author(s)
  K. Terada, S. Muro, A. Niimi, E. Ogawa, Y. Hoshino, S. Sato, T. Ohara, D, Kinose, A. Haruna, S. Marumo, M. Mishima
- Organizer
  European Respiratory Society
- Place of Presentation
  ストックホルム
- Year and Date
  2007-09-18
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Arterial Hypoxia Correlated with the Inflammatory Profile in Induced Sputum from COPD Patients,2007
- Author(s)
  A. Sato, M. D., S. Muro, M. D., Ph, S. Sato, M. D., Ph, M. Nishioka, M. D., Y. Hoshino, M. D., Ph, E. Ogawa, M. D., Ph, T. Hirai, M. D., Ph, H. Nakamura, M. D., Ph, J. Yodoi, M. D., Ph, M. Mishima, M. D
- Organizer
  American Thoracic Society
- Place of Presentation
  SanFrancisco
- Year and Date
  2007-05-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Thioredoxin Prevents Cigarette Smoke Induced Oxidative Stress and Apoptosis2006
- Author(s)
  A. Sato, Y. Hoshino, H. Nakamura, M.Narita, S. Muro, M. Mishima, J. Yodoi
- Organizer
  2006 International Conference of American Thoracic Society
- Place of Presentation
  San Diego Convention Center, San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Comparison of airway dimensions in different anatomic locations on chest CT in patients with COPD2006
- Author(s)
  Tadashi OHARA, Toyohiro HIRAI, Susumu SATO, Atsuyasu SATO, Michiyoshi NISHIOKA, Shigeo MURO, Michiaki MISHIMA
- Organizer
  11th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  Kyoto International Conference Hall, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Regulation of Connective Tissue Growth Factor Gene Expression by Lipopolysaccharide in Bronchial Epithelial Cells2006
- Author(s)
  M., Nishioka, E., Ogawa, T., Hirai, S., Muro, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  SanDiego American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Longitudinal deteriorations in patient centered versus physiological measurements in patients with COPD2006
- Author(s)
  T. Oga, K. Nishimura, M. Tsukino, S. Sato, T.Hajiro, M. Mishima
- Organizer
  16th Annual Congress of European Respiratory Society
- Place of Presentation
  International Congress Centre Munich, Munich, German
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Annual Changes in Computed Tomography Measurements and Pulmonary Function in Patients with Chronic Obstructive Pulmonary Disease2006
- Author(s)
  T. Ohara, T. Hirai, S. Sato, E. Ogawa, A. Sato,M. Nishioka, K. Terada, Kinose, S. Muro, M. Mishima
- Organizer
  2006 International Conference of American Thoracic Society
- Place of Presentation
  San Diego Convention Center, San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Body Mass Index in Patients with Chronic Obstructive Pulmonary Disease ; Correlation with Low Attenuation Areas on Computed Tomography2006
- Author(s)
  E. Ogawa, Y. Nakano, S. Muro, H. Sakai, T.Hirai, M. Mishima
- Organizer
  2006 International Conference of American Thoracic Society
- Place of Presentation
  San Diego Convention Center, San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-18209029
[Presentation] Body Mass Index in Patients with Chronic Obstructive Pulmonary Disease ; Correlation with Low Attenuation Areas on Computed Tomography2006
- Author(s)
  E., Ogawa, Y., Nakano, S., Muro, H., Sakai, T., Hirai, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  SanDiego American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Annual Changes in Computed Tomography Measurements and Pulmonary Function in Patients with Chronic Obstructive Pulmonary Disease2006
- Author(s)
  T., Ohara, T., Hirai, S., Sato, E., Ogawa, A. Sato, M., Nishioka, K., Terada, D., Kinose, S., Muro, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  SanDiego American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Thioredoxin Prevents Cigarette Smoke Induced Oxidative Stress and Apoptosis2006
- Author(s)
  A., Sato, Y., Hoshino, H., Nakamura, M., Narita, S., Muro, M., Mishima, J., Yodoi
- Organizer
  Thoracic Society
- Place of Presentation
  SanDiego American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] チオレドキシンによる喫煙肺傷害の抑制効2006
- Author(s)
  佐藤篤靖、星野勇馬、原富次郎、室繁郎、成田牧子、中村肇、三嶋理晃、淀井淳司
- Organizer
  第9回京都免疫ワークショップ学術集会プログラム「基礎及び臨床免疫学のクロストーク」
- Place of Presentation
  (京都)芝蘭会館(本館:稲盛ホール)
- Year and Date
  2006-04-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Airway Wall Thickening Assessed by CT Correlates with the Responsiveness to Bronchodilators in COPD Patient2005
- Author(s)
  S., Mum, S., Sato, Y,. Nishioka, T., Ohara, A., Sato, E., Ogawa, T., Hirai, T., Hajiro, M., Mishima, D., H., Horstman, S., R., Snapper, Y., Nakano
- Organizer
  Thoracic Society
- Place of Presentation
  SanDiego American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Time Course of Airway Resistance after Inhaled Bronchodilator in the Patients with COPD2005
- Author(s)
  S., Sato, T., Hirai, S., Muro, T., Ohara, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  SanDiego American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Thioredoxin Ameliorates Cigarette Smoke-Induced Local and Systemic Inflammation in Mice2005
- Author(s)
  A., Sato, Y., Hoshino, T., Ham, S., Muro, M., Narita, H., Nakamura, J., Yodoi, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  SanDiego American
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] Morphological Study of Emphysematous Lesion in Klotho Mice Using Fractal Analysis2004
- Author(s)
  A., Sato, T., Hirai, S., Muro, N., Kita, A., Imura, Y., Nabeshima, M., Mishima
- Organizer
  Thoracic Society
- Place of Presentation
  Seattle American
- Year and Date
  2004-05-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390234
[Presentation] 遺伝性呼吸器疾患の疾患特異的iPS細胞樹立
- Author(s)
  後藤慎平、伊藤功朗、三嶋理晃　他
- Organizer
  第５５回日本呼吸器学会総会
- Place of Presentation
  東京
- Year and Date
  2015-04-17 – 2015-04-19
- Data Source
  KAKENHI-PROJECT-22249031
[Presentation] 会長講演：COPD（慢性閉塞性肺疾患）の研究をふり返って～デジタル画像解析からiPS細胞研究まで～
- Author(s)
  三嶋理晃
- Organizer
  第112回日本内科学会講演会
- Place of Presentation
  京都
- Year and Date
  2015-04-10 – 2015-04-12
- Invited
- Data Source
  KAKENHI-PROJECT-22249031
[Presentation] Clinical application of iPS cell in the respiratory field including COPD and asthma.
- Author(s)
  Michiaki Mishima
- Organizer
  Asian Pacific Society of Respirology
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2014-11-13 – 2014-11-16
- Invited
- Data Source
  KAKENHI-PROJECT-22249031
[Presentation] Generation of alveolar epithelial cells from human pluripotent stem cells.
- Author(s)
  Shimpei Gotoh, Isao Ito, Tadao Nagasaki, Yuki Yamamoto, Satoshi Konishi, Yohei Korogi, Hisako Matsumoto, Shigeo Muro, Toyohiro Hirai, Michinori Funato, Shin-Ichi Mae, Taro Toyoda, Aiko Sato-Otsubo, Seishi Ogawa, Kenji Osafune, Michiaki Mishima
- Organizer
  ISSCR
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-22249031
[Presentation] 遺伝性呼吸器疾患の疾患特異的iPS細胞樹立
- Author(s)
  後藤慎平、伊藤功朗、三嶋理晃他
- Organizer
  第５５回日本呼吸器学会総会
- Place of Presentation
  東京
- Year and Date
  2015-04-17 – 2015-04-19
- Data Source
  KAKENHI-PROJECT-26293199

1. MURO Shigeo (60344454)

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Mishima Michiaki 三嶋 理晃

MISHIMA Michiaki 三嶋 理晃

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Application of iPS cell technology to lung regeneration and development of bioresource for elucidating the mechanisms of lung diseasesPrincipal Investigator

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Researches using iPS cells on intractable respiratory diseases to elucidate their pathogenesis and develop novel therapy.Principal Investigator

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Comprehensive study on the phenotyping of COPDPrincipal Investigator

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Study on the COPD therapy based on the airway dimension measured by CT imagingPrincipal Investigator

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Analysis of Emphysema and Airway Lesion in Patients with COPDPrincipal Investigator

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Acute response of lung mechanics to hypoxia and histaminePrincipal Investigator

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Mishima Michiaki 三嶋理晃

MISHIMA Michiaki 三嶋理晃

[Journal Article] Emphysema and airway disease affect within-breath changes in　respiratory resistance in COPD patients.2015

[Journal Article] A toll-like receptor 3 single nucleotide polymorphism in　Japanese patients with sarcoidosis.2015