Endo Shogo 遠藤昌吾

… Alternative Names

ENDO Shogo 遠藤昌吾

遠藤省吾エンドウショウゴ

遠藤昌吾エンドウショウゴ

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Researcher Number	60192514
Other IDs	https://orcid.org/0000-0002-3948-8723
Affiliation (Current)	2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長
Affiliation (based on the past Project Information) *help	2013 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 2013 – 2016: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), その他部局等, その他 2014 – 2015: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究部長 2012: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 老化脳神経科学研究チーム, 研究部長 2012: 地方独立行政法人東京都健康長寿医療センター研究所, 老化制御研究チーム, 研究部長 … More 2011: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究部長 2010: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 研究部長 2006 – 2007: 沖縄科学技術研究基盤整備機構, 記憶と学習の分子神経生物学ユニット, 代表研究者 2004: RIKEN, Research Unit, Unit Leader, 遠藤研究ユニット, ユニットリーダー 2003: 独立行政法人理化学研究所, 神経回路メカニズム研究グループ, 上級研究員 2001 – 2002: Neuronal Circuit Mechanism Research Group, RIKEN Senior Scientist, 神経回路メカニズム研究グループ, 上級研究員 2000: 理化学研究所, 神経回路メカニズム研究グルーブ, 上級研究員 1998 – 2000: 理化学研究所, 記憶学習機構研究チーム, 研究員 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Neuroscience in general / Basic Section 59040:Nutrition science and health science-related / Applied health science / Biological Sciences / Biological Sciences Except Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology / Neurochemistry/Neuropharmacology / Neuroscience in general / Biological Sciences
Keywords	Principal Investigator 小脳 / 記憶 / 一酸化窒素 / cGMP / 8-ニトロ-cGMP / 活性酸素種 / LTD / プルキンエ細胞 / 認知機能 / ROS … More / 長期抑圧 / 遺伝子欠損マウス / 学習 / 老化 / 加齢 / Nitric oxide / ERK / プロテアーゼ / 老廃物除去 / CCAS / 可塑性 / 記憶・学習 / シグナル伝達 / 連合性 / PKG / 連合性検出器 / ホスホジエステラーぜ / バイオマーカー / 握力 / 遺伝子改変マウス / AMP / マウス / 包括的行動解析 / 認知的フレイル / 炎症 / cAMP / シロスタゾール / フレイル / 注意 / 身体機能 / NO / LTP/LTD / 神経可塑性 / 運動記憶 / 8-nitro-cGMP / ビタミン / 長期記憶 / 運動学習 / ビタミンE / アスコルビン酸 / 運動 / 分散効果 / gene deficient mice / nuclear translocation / MAP kinase / IoxP / Cre / loxP / ERK2 / Cre-LoxP / 核内移行 / MAPキナーゼ / Synaptic transmission / Cerebellum / プロテインホスファターゼ / G-substrate / 神経伝達 / 分散学習 / 休憩 / グアニル化 / 眼球運動 / リハビリテーション / MEK / MAPK / プロテアソーム / カルパイン / 記憶学習 … More Except Principal Investigator 細胞内情報伝達 / ERK / ノックアウトマウス / 神経毒性 / 全身麻酔薬 / 自閉症 / 疼痛 / セボフルラン / ＥＲＫ / 臨界期 / 神経発達 / 発達 / 小児 / 麻酔 / マウス / 発達期 / 神経 / 感作 / 代謝 / 神経障害性疼痛 / 炎症性疼痛 / ERK1 / 脊髄 / 中枢性感作 / ERK5 / ERK2 / アポトーシス / 神経回路 / 吸入麻酔薬 / sevoflurane / mouse / toxicity / developing brain / apoptosis / general anesthetics / 転写調節因子 / 海馬ニューロン / 神経突起 / cAMP / 最初期遺伝子 / CRE転写調節 / 樹状突起スパイン / 突起伸長 / PC12細胞 / 遺伝子発現 / シナプス可塑性 / 行動実験 / 脳 / 母性行動 / 水素 / 記憶・学習 / 育児 / 分化・増殖 / 神経幹細胞 / 極性異常 / 上皮細胞 / がん細胞 / MAP4K / Rap2 / シグナル伝達 / 癌 Less

Aging cerebellum and cognitive declinePrincipal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Cognitive impairment viewed from the aging cerebellumPrincipal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
慢性疼痛発症におけるERK細胞内情報伝達機構の役割
- Principal Investigator
  
  高橋哲也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  National Defense Medical College
発達期の脳における全身麻酔薬の神経毒性メカニズムの解明
- Principal Investigator
  
  佐藤泰司
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  National Defense Medical College
Roles of 8-nitro-cGMP pathway as the coincident detector for memory formation.Principal Investigator
- Principal Investigator
  
  Endo Shogo
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Reactive oxygen species; physiological role in the brainPrincipal Investigator
- Principal Investigator
  
  Endo Shogo
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Association of cognitive frailty and signal transduction disfunction.Principal Investigator
- Principal Investigator
  
  Endo Shogo
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
The role of extracellular signal-regulated kinase (ERK) in pathological pain
- Principal Investigator
  
  Masanori Kawaguchi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  National Defense Medical College
Motor memory and anti-oxidant agentsPrincipal Investigator
- Principal Investigator
  
  Endo Shogo
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Effects of general anesthetics on the regulatory mechanisms of neuronal development in the critical period
- Principal Investigator
  
  SATOH YASUSHI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  National Defense Medical College
Screening of molecules responsible for signaling from nucleus to synapses in emotional memory
- Principal Investigator
  
  Kojima Nobuhiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Toyo University
活性酸素種が担うマウス運動記憶の分散効果Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Neurotoxicity of general anesthetics in the developing brain
- Principal Investigator
  
  KAZAMA TOMIEI
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  National Defense Medical College
Mechanisms underlying spacing effect of memoryPrincipal Investigator
- Principal Investigator
  
  ENDO Shogo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Study for the Function of ERK2 in the Brain Using ERK2 Conditional Knockout Mouse
- Principal Investigator
  
  SATOH Yasushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  防衛医科大学校
   National Defense Medical College
低分子量G蛋白質Rap2とがん細胞の分化異常
- Principal Investigator
  
  苅谷研一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of the Ryukyus
Comprehensive examination of physiological role of ERK2 in neuronal cells.Principal Investigator
- Principal Investigator
  
  ENDO Shogo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  RIKEN
小脳の神経可塑性に関与するNOカスケードの研究Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
脳内NOカスケード構成因子G-substrate欠損マウスの解析Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Studies on the nitric oxide cascade involved in neuronal plasticity.Principal Investigator
- Principal Investigator
  
  ENDO Shogo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  RIKEN
シナプス可塑性に関与するプロテアーゼに関する研究Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The Institute of Physical and Chemical Research
記憶の維持に関与するプロテアーゼの研究Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research

[Book] Clinical　Neuroscience2013
- Author(s)
  遠藤昌吾
- Total Pages
  97
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25293331
[Book] Brain Aging and Therapeutic Interventions (Thakur and Rattan Ed.)2013
- Author(s)
  Shogo Endo
- Total Pages
  296
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25560382
[Book] Clinical　Neuroscience2013
- Author(s)
  佐藤泰司、遠藤昌吾
- Total Pages
  97
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25293331
[Journal Article] Metabolic Remodeling with Hepatosteatosis Induced Vascular Oxidative Stress in Hepatic ERK2 Deficiency Mice with High Fat Diets2022
- Author(s)
  Kujiraoka Takehiko、Kagami Kazuki、Kimura Toyokazu、Ishinoda Yuki、Shiraishi Yasunaga、Ido Yasuo、Endo Shogo、Satoh Yasushi、Adachi Takeshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8521-8521
- DOI
  10.3390/ijms23158521
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752, KAKENHI-PROJECT-20K17204
[Journal Article] Reversal of spatial memory impairment by phosphodiesterase 3 inhibitor cilostazol is associated with reduced neuroinflammation and increased cerebral glucose uptake in aged male mice2022
- Author(s)
  Yanai Shuichi、Tago Tetsuro、Toyohara Jun、Arasaki Tomoko、Endo Shogo
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 1031637-1031637
- DOI
  10.3389/fphar.2022.1031637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07663, KAKENHI-PROJECT-22K11872, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Study of aging using circuit tests and parametric analysis2022
- Author(s)
  Konishi Tomokazu、Yanai Shuichi、Endo Shogo
- Journal Title
  
  bioRxiv,
  
  Volume: 1 Pages: 1-1
- DOI
  10.1101/2022.03.24.485723
- Open Access
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] Endothelial Extracellular Signal‐Regulated Kinase/Thromboxane A2/Prostanoid Receptor Pathway Aggravates Endothelial Dysfunction and Insulin Resistance in a Mouse Model of Metabolic Syndrome2022
- Author(s)
  Sato Atsushi、Yumita Yusuke、Kagami Kazuki、Ishinoda Yuki、Kimura Toyokazu、Osaki Ayumu、Toya Takumi、Namba Takayuki、Endo Shogo、Ido Yasuo、Nagatomo Yuji、Satoh Yasushi、Adachi Takeshi
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 11 Issue: 23
- DOI
  10.1161/jaha.122.027538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Long-term D-Allose Administration Favorably Alters the Intestinal Environment in Aged Male Mice2022
- Author(s)
  Tomoya Shintani, Shuichi Yanai, Akane Kanasaki, Misuzu Tanaka, Tetsuo Iida, Genki Ozawa, Tadao Kunihiro, & Shogo Endo
- Journal Title
  
  Journal of Applied Glycoscience
  
  Volume: 69 Issue: 4 Pages: 97-102
- DOI
  10.5458/jag.jag.JAG-2022_0005
- ISSN
  1344-7882, 1880-7291
- Year and Date
  2022-11-20
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11872, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] 細胞のメカニズムと神経疾患：細胞内シグナル伝達の基礎①, ERK2022
- Author(s)
  佐藤泰司,遠藤昌吾
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 70 Pages: 814-816
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] 細胞のメカニズムと神経疾患：細胞内シグナル伝達の基礎①, ERK2022
- Author(s)
  佐藤泰司,遠藤昌吾
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 70 Pages: 814-816
- Data Source
  KAKENHI-PROJECT-21K19752
[Journal Article] Extracellular signal‐regulated kinases 2 (Erk2) and Erk5 in the central nervous system differentially contribute to central sensitization in male mice2021
- Author(s)
  Matsuura Fumihiro、Satoh Yasushi、Itakura Sayako、Morohashi Toru、Kawaguchi Masanori、Takahashi Tetsuya、Iwanaga Koji、Terashima Hayato、Kobayashi Yasushi、Wang Xin、Ishizuka Toshiaki、Endo Shogo、Ikeda Takehiko
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 99 Issue: 6 Pages: 1666-1688
- DOI
  10.1002/jnr.24827
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11548, KAKENHI-PROJECT-18K08878, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752, KAKENHI-PROJECT-21K16555
[Journal Article] Role of G-Substrate in the NO/cGMP/PKG Signal Transduction Pathway for Photic Entrainment of the Hamster Circadian Clock2021
- Author(s)
  Plano Santiago Andr?s、Alessandro Mar?a Soledad、Trebucq Laura Luc?a、Endo Shogo、Golombek Diego Andr?s、Chiesa Juan Jos?
- Journal Title
  
  ASN Neuro
  
  Volume: 13 Pages: 175909142098492-175909142098492
- DOI
  10.1177/1759091420984920
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Tocotrienols reach the brain and play roles in the attenuation of body weight gain and improvement of cognitive function in high-fat diet-treated mice2021
- Author(s)
  Kato Yugo、Uchiumi Hayami、Usami Ryo、Takatsu Hirokatsu、Aoki Yoshinori、Yanai Shuichi、Endo Shogo、Fukui Koji
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 69 Issue: 3 Pages: 256-264
- DOI
  10.3164/jcbn.21-10
- NAID
  130008110247
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Functional Aging in Male C57BL/6J Mice Across the Life-Span: A Systematic Behavioral Analysis of Motor, Emotional, and Memory Function to Define an Aging Phenotype2021
- Author(s)
  Yanai Shuichi、Endo Shogo
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 13 Pages: 697621-697621
- DOI
  10.3389/fnagi.2021.697621
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Central, but not peripheral, nervous ERK2 is essential for itch signals in murine allergic skin inflammation.2021
- Author(s)
  Matsuo S, Hashimoto T, Matsuura F, Imamura O, Endo S, Satoh Y, Satoh T.
- Journal Title
  
  Allergy
  
  Volume: 76 Issue: 11 Pages: 3422-3432
- DOI
  10.1111/all.14867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08805, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Inhibition of extracellular signal-regulated kinase pathway suppresses tracheal stenosis in a novel mouse model2021
- Author(s)
  Kimura Akari、Araki Koji、Satoh Yasushi、Mogi Sachiyo、Fujitani Kazuko、Kurioka Takaomi、Endo Shogo、Shiotani Akihiro、Yamashita Taku
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 9 Pages: 0256127-0256127
- DOI
  10.1371/journal.pone.0256127
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09390, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752, KAKENHI-PROJECT-19K18782, KAKENHI-PROJECT-20K18263
[Journal Article] 記憶を守る2020
- Author(s)
  遠藤昌吾
- Journal Title
  
  内藤財団時報
  
  Volume: 105 Pages: 37-37
- Data Source
  KAKENHI-PROJECT-19K22834
[Journal Article] 認知症と老化に伴う記憶低下の予防と制御―細胞内シグナル伝達系を標的として―2020
- Author(s)
  柳井修一・遠藤昌吾
- Journal Title
  
  医学のあゆみ
  
  Volume: 273 Pages: 1095-1101
- Data Source
  KAKENHI-PROJECT-19K22834
[Journal Article] 認知症と老化に伴う記憶低下の予防と制御―細胞内シグナル伝達系を標的として― Prevention and control of age-related memory decline and dementia2020
- Author(s)
  柳井修一、遠藤昌吾
- Journal Title
  
  医学のあゆみ
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] 神経細胞レベルのシナプス可塑性（海馬と小脳におけるシナプス可塑性）2020
- Author(s)
  遠藤昌吾
- Journal Title
  
  ヒトの動きの神経科学シリーズ-IV- 運動学習の脳・神経科学（大築、鈴木、柳原編集）
  
  Volume: 4 Pages: 20-39
- Data Source
  KAKENHI-PROJECT-19K22834
[Journal Article] 記憶を守る2020
- Author(s)
  遠藤昌吾
- Journal Title
  
  内藤財団時報
  
  Volume: 105 Pages: 105-105
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] Induction of ICER is superseded by smICER, challenging the impact of ICER under chronic beta‐adrenergic stimulation2020
- Author(s)
  Seidl Matthias D.、Fels Benedikt、Kranick Daniel、Sternberg Alexandra、Grimm Kristina、St?mpel Frank T.、Pluteanu Florentina、Schulte Jan S.、Heinick Alexander、Kojima Nobuhiko、Endo Shogo、Huge Andreas、Stoll Monika、M?ller Frank U.
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 8 Pages: 11272-11291
- DOI
  10.1096/fj.201902301rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-19H04044
[Journal Article] モデルマウスを用いた記憶障害メカニズムの解析2019
- Author(s)
  遠藤昌吾
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 859-863
- NAID
  130007700026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22834
[Journal Article] Vitamin C and vitamin E double-deficiency increased neuroinflammation and impaired conditioned fear memory2019
- Author(s)
  Takahashi Keita、Yanai Shuichi、Takisawa Shoko、Kono Nozomu、Arai Hiroyuki、Nishida Yoichiro、Yokota Takanori、Endo Shogo、Ishigami Akihito
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 663 Pages: 120-128
- DOI
  10.1016/j.abb.2019.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-17H05053, KAKENHI-PROJECT-18K07460, KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-19H04043, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-17H06164
[Journal Article] モデルマウスを用いた記憶障害メカニズムの解析2019
- Author(s)
  遠藤昌吾
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 859-863
- NAID
  130007700026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling2019
- Author(s)
  Katagiri Takaharu、Yamazaki Soh、Fukui Yuto、Aoki Kotaro、Yagita Hideo、Nishina Takashi、Mikami Tetuo、Katagiri Sayaka、Shiraishi Ayako、Kimura Soichiro、Tateda Kazuhiro、Sumimoto Hideki、Endo Shogo、Kameda Hideto、Nakano Hiroyasu
- Journal Title
  
  Mucosal Immunology
  
  Volume: 12 Issue: 5 Pages: 1104-1117
- DOI
  10.1038/s41385-019-0182-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07516, KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-17K08994, KAKENHI-PROJECT-19K07391
[Journal Article] 8-Nitro-cGMP attenuates context-dependent fear memory in mice.2019
- Author(s)
  Kishimoto Y, Kasamatsu S, Yanai S, Endo S, Akaike T, Ihara H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 511 Issue: 1 Pages: 141-147
- DOI
  10.1016/j.bbrc.2019.01.138
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-17K17583, KAKENHI-PROJECT-18K07460, KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-19H04044
[Journal Article] Up-regulation of NSP3 by Oligomeric Aβ Accelerates Neuronal Death Through Cas-independent Rap1A Activation2018
- Author(s)
  Gomi Fujiya、Uchida Yoko、Endo Shogo
- Journal Title
  
  Neuroscience
  
  Volume: 386 Pages: 182-193
- DOI
  10.1016/j.neuroscience.2018.06.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] PDE3 Inhibitors Repurposed as Treatments for Age-Related Cognitive Impairment2018
- Author(s)
  Yanai Shuichi、Endo Shogo
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 印刷中 Issue: 6 Pages: 4306-4316
- DOI
  10.1007/s12035-018-1374-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-18K07460
[Journal Article] Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages2018
- Author(s)
  Bohn T、Rapp S、Luther N、Klein M、Bruehl T-J、Kojima N、Aranda L P、Hahlbrock J、Muth S、Endo S、Pektor S、Brand A、Renner K、Popp V、Gerlach K、Vogel D、Lueckel C、Arnold-Schild D、Pouyssegur J、Kreutz M、Huber M、Koenig J、Weigmann B、Probst H-C、von Stebut E、Becker C、Schild H、Schmitt E、Bopp T
- Journal Title
  
  Nature Immunology
  
  Volume: 19 Issue: 12 Pages: 1319-1329
- DOI
  10.1038/s41590-018-0226-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] The role of Purkinje cell-derived VEGF in cerebellar astrogliosis in Niemann-Pick type C mice2018
- Author(s)
  Park Min Hee、Lee Ju Youn、Jeong Min Seock、Jang Hyung Sup、Endo Shogo、Bae Jae-sung、Jin Hee Kyung
- Journal Title
  
  BMB Reports
  
  Volume: 51 Issue: 2 Pages: 79-84
- DOI
  10.5483/bmbrep.2018.51.2.168
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Long-term cilostazol administration prevents age-related decline of hippocampus-dependent memory in mice2018
- Author(s)
  Yanai Shuichi、Ito Hideki、Endo Shogo
- Journal Title
  
  Neuropharmacology
  
  Volume: 129 Pages: 57-68
- DOI
  10.1016/j.neuropharm.2017.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] The AP-1 transcription factor JunB is required for Th17 cell differentiation2017
- Author(s)
  Yamazaki Soh、Tanaka Yoshihiko、Araki Hiromitsu、Kohda Akira、Sanematsu Fumiyuki、Arasaki Tomoko、Duan Xuefeng、Miura Fumihito、Katagiri Takaharu、Shindo Ryodai、Nakano Hiroyasu、Ito Takashi、Fukui Yoshinori、Endo Shogo、Sumimoto Hideki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 17402-17402
- DOI
  10.1038/s41598-017-17597-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01378, KAKENHI-PROJECT-16K08627, KAKENHI-PROJECT-16K08747, KAKENHI-PROJECT-17K19533, KAKENHI-PUBLICLY-17H05804, KAKENHI-PLANNED-26110003, KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-17H04371, KAKENHI-PROJECT-15J03454, KAKENHI-PROJECT-16K15681, KAKENHI-PROJECT-16K15792, KAKENHI-PROJECT-17K08994
[Journal Article] Data on the optimization of behavioral tasks for senescence-accelerated mouse prone 8 (SAMP8)2017
- Author(s)
  S. Yanai and S. Endo
- Journal Title
  
  Data in Brief
  
  Volume: 8 Pages: 262-266
- DOI
  10.1016/j.dib.2016.05.044
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Long-term cilostazol administration ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8) through a dual effect on cAMP and blood-brain barrier.2017
- Author(s)
  Yanai S, Toyohara J, Ishiwata K, Ito H, Endo S.
- Journal Title
  
  Neuropharmacology
  
  Volume: 116 Pages: 246-259
- DOI
  10.1016/j.neuropharm.2016.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-15H03103
[Journal Article] cAMP系増強薬と認知症の治療－既存薬再開発の応用－2017
- Author(s)
  柳井修一、遠藤昌吾
- Journal Title
  
  Geriatric Medicine
  
  Volume: 5 Pages: 23-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Early onset of behavioral alterations in senescence-accelerated mouse prone 8 (SAMP8).2016
- Author(s)
  Yanai S, Endo S.
- Journal Title
  
  Behavioural Brain Research
  
  Volume: in press Pages: 187-195
- DOI
  10.1016/j.bbr.2016.04.026
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24730642, KAKENHI-PROJECT-15H03103
[Journal Article] Preclinical and the first-in-man studies on [11C]CB184 for imaging 18 kDa translocator protein by positron emission tomography2016
- Author(s)
  J.Toyohara, M. Sakata, K. Hatano, S. Yanai, S. Endo, K. Ishibashi, K. Wagatsuma, K. Ishii and K. Ishiwata
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 30 Issue: 8 Pages: 534-543
- DOI
  10.1007/s12149-016-1094-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-25293271
[Journal Article] Suppression of ERK phosphorylation through oxidative stress is involved in the mechanism underlying sevoflurane-induced toxicity in the developing brain2016
- Author(s)
  Yufune S, Satoh Y, Akai R, Ｙoshinaga Y, Kobayashi Y., Endo S, Kazama T.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 21859-21859
- DOI
  10.1038/srep21859
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04970, KAKENHI-PROJECT-25293331, KAKENHI-PROJECT-15H03103
[Journal Article] Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.2016
- Author(s)
  Tanahashi, H.;Tian, Q.B.; Hara, Y.;Sakagami, H.;Endo, S.;Suzuki, T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 20241-20241
- DOI
  10.1038/srep20241
- NAID
  120007100143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26115532, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-26430014
[Journal Article] 巨大地震が飼育動物へ及ぼす影響2015
- Author(s)
  柳井修一、遠藤昌吾
- Journal Title
  
  LABIO21
  
  Volume: 59 Pages: 20-24
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Impaired Th2 differentiation of CD4+ T cells from Rap2b knockout mice.2015
- Author(s)
  Y. Uechi, G. Matsuzaki, M. Suzuki, T. Asato, K. Takei, M. Umikawa, M. Oshiro, I. Maruyama, S. Endo and K Kariya
- Journal Title
  
  Ryukyu Med. J
  
  Volume: 34 Pages: 45-52
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26115532
[Journal Article] Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice.2015
- Author(s)
  S. Yufune, Y. Satoh, I. Takamatsu, H. Ohta, Y. Kobayashi, Y. Takaenoki, G. Pages, J. Pouyssgur, S. Endo, and T. Kazama.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Pages: 102521-102521
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Impaired Th2 differentiation of CD4+ T cells from Rap2b knockout mice.2015
- Author(s)
  Y. Uechi, G. Matsuzaki, M. Suzuki, T. Asato, Kimiko Takei, M. Umikawa, M. Oshiro, I. N. Maruyama, S. Endo and K.-I. Kariya
- Journal Title
  
  Ryukyu Med. J.
  
  Volume: 34 Pages: 45-52
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice2015
- Author(s)
  Yufune S., Satoh Y., Takamatsu I., Ohta H., Kobayashi Y., Takaenoki Y., Pagès G, Pouysségur J, Endo S, and Kazama T.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 10252-10252
- DOI
  10.1038/srep10252
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04970, KAKENHI-PROJECT-25293331, KAKENHI-PUBLICLY-26115532
[Journal Article] Knowledge of Signal Transduction Provides an Approach to Attacking Memory Decline.2015
- Author(s)
  S. Yanai and S. Endo
- Journal Title
  
  Aging Mechanisms; Longevity, Metabolism, and Brain Aging (N. Mori, and I. Mook-Jung, Inhee eds),
  
  Volume: 1 Pages: 257-274
- Data Source
  KAKENHI-PUBLICLY-26115532
[Journal Article] 巨大地震が飼育動物へ及ぼす影響2015
- Author(s)
  柳井修一、遠藤昌吾
- Journal Title
  
  LABIO21
  
  Volume: 59 Pages: 20-24
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26115532
[Journal Article] Knowledge of Signal Transduction Provides an Approach to Attacking Memory Decline.2015
- Author(s)
  S. Yanai and S. Endo
- Journal Title
  
  Aging Mechanisms; Longevity, Metabolism, and Brain Aging (N. Mori, and I. Mook-Jung, Inhee eds)
  
  Volume: 1 Pages: 257-274
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss2015
- Author(s)
  Kurioka T, Matsunobu T, Satoh Y, Niwa K, Endo S, Fujioka M, Shiotani A.
- Journal Title
  
  Scientific Reports
  
  Volume: 18;5 Issue: 1 Pages: 16839-16839
- DOI
  10.1038/srep16839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-15H04970, KAKENHI-PROJECT-15H04991, KAKENHI-PUBLICLY-26115532
[Journal Article] Targeted deletion of ERK2 in cardiomyocytes attenuates hypertrophic response but provokes pathological stress induced cardiac dysfunction.2014
- Author(s)
  Ulm S, Liu W, Zi M, Tsui H, Chowdhury SK, Endo S, Satoh Y, Prehar S, Wang R, Cartwright EJ, Wang X.
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 72C Pages: 104-116
- DOI
  10.1016/j.yjmcc.2014.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293331, KAKENHI-PROJECT-25560382, KAKENHI-PUBLICLY-26115532
[Journal Article] The effect of diazepam on mouse PTSD-like behaviors induced by the 2011 Tohoku earthquake2014
- Author(s)
  S. Yanai, Y. Semba, and S. Endo.
- Journal Title
  
  Behav Sci Res
  
  Volume: 53 Pages: 27-36
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26115532
[Journal Article] Cilostazol improves hippocampus-dependent long-term memory in mice2014
- Author(s)
  Shuichi Yanai, Yuki Semba, Hideki Ito, & Shogo Endo
- Journal Title
  
  Psychopharmacology
  
  Volume: - Issue: 13 Pages: 2681-2693
- DOI
  10.1007/s00213-014-3442-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24730642, KAKENHI-PROJECT-25560382
[Journal Article] Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy.2014
- Author(s)
  P. Srimontri, S. Endo, T. Sakamoto, Y. Nakayama, A. Kurosaka, S. Itohara, Y. Hirabayashi, K Kato.
- Journal Title
  
  J Neurochem.
  
  Volume: 131 Issue: 5 Pages: 675-687
- DOI
  10.1111/jnc.12838
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560382, KAKENHI-PUBLICLY-26115532
[Journal Article] The effect of diazepam on mouse PTSD-like behaviors induced by the 2011 Tohoku earthquake.2014
- Author(s)
  S. Yanai, Y. Semba, and S. Endo.
- Journal Title
  
  Behav Sci Res
  
  Volume: 53 Pages: 27-36
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560382
[Journal Article] Deficits in memory-guided limb movements impair obstacle avoidance locomotion in Alzheimer’s disease mouse model2014
- Author(s)
  Setogawa S, Yamaura H, Arasaki T, Endo S, Yanagihara D
- Journal Title
  
  Scientific Reports
  
  Volume: 4:7200 Issue: 1 Pages: 1-10
- DOI
  10.1038/srep07220
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J09496, KAKENHI-PROJECT-25560295, KAKENHI-PROJECT-25560382, KAKENHI-PUBLICLY-26115532
[Journal Article] MAPKカスケード2013
- Author(s)
  佐藤泰司、遠藤昌吾
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 649-649
- Data Source
  KAKENHI-PROJECT-25560382
[Journal Article] 神経可塑性・記憶におけるMEK1/2-ERK1/2の役割、2013
- Author(s)
  遠藤昌吾
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 688-691
- Data Source
  KAKENHI-PROJECT-25560382
[Journal Article] MAPKカスケード2013
- Author(s)
  佐藤泰司遠藤昌吾
- Journal Title
  
  Clinical Neuroscience「神経系のMAPキナーゼ」
  
  Volume: Vol 31 Pages: 649-649
- URL
  https://www.chugaiigaku.jp/modules/shop/index.php?main_page=product_info&products_id=1357&PHPSESSID=45c0649080e6cbc570e285dc7e914f81
- Data Source
  KAKENHI-PROJECT-22500304
[Journal Article] Deep cerebellar nuclei play an important role in two-tone discrimination on delay eyeblink conditioning in C57BL/6 mice.2013
- Author(s)
  Sakamoto, T., and Endo, S.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 3 Pages: e59880-e59880
- DOI
  10.1371/journal.pone.0059880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240057, KAKENHI-PROJECT-25293331, KAKENHI-PROJECT-25560382
[Journal Article] Hepatic extracellular signal-regulated kinase 2 suppresses endoplasmic reticulum stress and protects from oxidative stress and endothelial dysfunction2013
- Author(s)
  Kujiraoka T, Satoh Y, Ayaori M, Shiraishi Y, Arai-Nakaya Y, Hakuno D, Yada H, Kuwada N, Endo S, Isoda K, Adachi T.
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 2 Issue: 4
- DOI
  10.1161/jaha.113.000361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293331, KAKENHI-PROJECT-25560382
[Journal Article] Mechanical allodynia but not thermal hyperalgesia is impaired in mice deficient for ERK2 in the central nervous system2012
- Author(s)
  Otsubo Y., Satoh Y., Kodama M., Araki Y., Satomoto M., Sakamoto E., Pages G., Pouyssegur J., Endo S., Kazama T.
- Journal Title
  
  PAIN
  
  Volume: 153 Issue: 11 Pages: 2241-2252
- DOI
  10.1016/j.pain.2012.07.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500304, KAKENHI-PROJECT-23593009
[Journal Article] ERK2 contributes to the control of social behaviors in mice2011
- Author(s)
  Satoh Y., Endo S., Nakata T., Kobayashi Y., Yamada K., Ikeda T., Takeuchi A., Hiramoto T., Watanabe Y., Kazama T
- Journal Title
  
  J. Neuroscience
  
  Volume: 31(33) Issue: 33 Pages: 11953-67
- DOI
  10.1523/jneurosci.2349-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500304
[Journal Article] シナプスにおけるERKシグナリングの役割2010
- Author(s)
  佐藤泰司、遠藤昌吾
- Journal Title
  
  生体の科学
  
  Volume: Vol 61 Pages: 460-461
- Data Source
  KAKENHI-PROJECT-22500304
[Journal Article] 神経系におけるMEK1/2の機能2010
- Author(s)
  佐藤泰司、遠藤昌吾
- Journal Title
  
  生体の科学
  
  Volume: Vol 61 Pages: 462-463
- Data Source
  KAKENHI-PROJECT-22500304
[Journal Article] Protein phosphatase 2A inhibition induces cerebellar long-term depression and declustering of synaptic AMPA receptor.2004
- Author(s)
  Launey T., Endo S., Sakai R., Harano J., Ito M.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 101
  
  Pages: 676-681
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] ERKs regulate PKC-dependent synaptic depression and declustering of glutamate receptors in cerebellar Purkinje cells.2003
- Author(s)
  Endo S., Launey T.
- Journal Title
  
  Neuropharmacology 45
  
  Pages: 863-872
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] Nitric oxide activates extracellular signal-regulated kinase 1/2 and enhances declustering of ionotropic glutamate receptor subunit 2/3 in rat cerebellar Purkinje cells.2003
- Author(s)
  Endo S., Launey T.
- Journal Title
  
  Neuroscience Lett. 350
  
  Pages: 37777-37782
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] ERKs regulate PKC-dependent synaptic depression and declustering of glutamate receptors in cerebellar Purkinje cells.2003
- Author(s)
  Endo S., Launey T.
- Journal Title
  
  J.Biol.Chem. 45
  
  Pages: 122-126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] Glial protein S100B modulates long-term neuronal synaptic plasticity.2002
- Author(s)
  Nishiyama H., Knopfel T., Endo S., Itohara S.
- Journal Title
  
  Proc.Natl.Acad.Sci USA. 99
  
  Pages: 4037-4042
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] Impairment of conditioned freezing to tone, but not to context, in Fyn-transgenic mice : Relationship to NMDA receptor subunit 2B function.
- Author(s)
  Kojima N., Sakamoto T., Endo S., Niki H.
- Journal Title
  
  Eur.J.Neurosci. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Patent] 加齢に伴う認知機能の低下予防又は改善用の組成物2020
- Inventor(s)
  遠藤・柳井・飯田・新谷
- Industrial Property Rights Holder
  遠藤・柳井・飯田・新谷
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] 柿澤　昌、遠藤　昌吾2023
- Author(s)
  柿澤　昌、遠藤　昌吾
- Organizer
  第147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] Involvement of 8-nitro-cGMP ? ERK signals in induction of long-term depression in the mouse cerebellum2022
- Author(s)
  柿澤昌、新崎智子、佐藤泰司、遠藤昌吾
- Organizer
  第95回日本薬理学会年会シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Combined administration of donepezil and cilostazol ameliorates spatial memory impairment in APP knock-in mouse model for Alzheimer's disease.2022
- Author(s)
  S Yanai, T Arasaki, T Saito, T Saido & S Endo.
- Organizer
  第45回日本神経科学大会 (Neuro2022)
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] ホスホジエステラーゼ3阻害剤シロスタゾールによる老化マウスの記憶機能低下の改善と予防2022
- Author(s)
  柳井修一・新崎智子,遠藤昌吾
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of 8-nito-cGMP - ERK signals in the induction of long-term depression in the mouse cerebellum.2022
- Author(s)
  S Kakizawa, T Arasaki, Yasushi Satoh, S Endo.
- Organizer
  2022
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of 8-nitro-cGMP ? ERK signals in induction of long-term depression in the mouse cerebellum2022
- Author(s)
  柿澤昌、新崎智子、佐藤泰司、遠藤昌吾
- Organizer
  第95回日本薬理学会年会シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] Assessment of physical and cognitive frailty in aging mouse model. 22nd World Congress of Gerontology and Geriatrics2022
- Author(s)
  S Yanai, T Arasaki & S Endo
- Organizer
  22nd World Congress of Gerontology and Geriatrics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Combined administration of donepezil and cilostazol ameliorates spatial memory impairment in APP knock-in mouse model for Alzheimer's disease.2022
- Author(s)
  S Yanai, T Arasaki, T Saito, T Saido & S Endo.
- Organizer
  第45回日本神経科学大会 (Neuro2022)
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] 24か月齢アルツハイマー病モデルマウスにおける行動と記憶の性差に関する基礎研究2022
- Author(s)
  張碩文,柳井修一,吉原利典,斉藤貴志,西道隆臣,遠藤昌吾,後藤佐多良,内藤久士．
- Organizer
  第77回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] 24か月齢アルツハイマー病モデルマウスにおける行動と記憶の性差に関する基礎研究．2022
- Author(s)
  張碩文,柳井修一,吉原利典,斉藤貴志,西道隆臣,遠藤昌吾,後藤佐多良,内藤久士
- Organizer
  第77回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] ホスホジエステラーゼ3阻害剤シロスタゾールによる老化マウスの記憶機能低下の改善と予防．2022
- Author(s)
  柳井修一・新崎智子,遠藤昌吾．
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] Tocotrienols attenuate diet-induced obesity development.2022
- Author(s)
  Y Kato, S Yanai, S Endo, K Fukui
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Assessment of physical and cognitive frailty in aging mouse model.2022
- Author(s)
  S Yanai, T Arasaki & S Endo.
- Organizer
  22nd World Congress of Gerontology and Geriatrics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] シロスタゾールとドネペジルの低用量併用による老齢マウスの記憶機能改善．2021
- Author(s)
  柳井修一, 新崎智子, 遠藤昌吾
- Organizer
  日本心理学会第85回大会
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] Comparison of age-related multi-domain phenotype in human and mouse using comprehensive behavioral test battery.2021
- Author(s)
  S Yanai, T Arasaki & S Endo
- Organizer
  第44回日本神経科学大会 / CJK第1回国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Comparison of age-related multi-domain phenotype in human and mouse using comprehensive behavioral test battery.2021
- Author(s)
  S Yanai, T Arasaki & S Endo.
- Organizer
  第44回日本神経科学大会 / CJK第1回国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] シロスタゾールとドネペジルの低用量併用による老齢マウスの記憶機能改善2021
- Author(s)
  柳井修一, 新崎智子, 遠藤昌吾
- Organizer
  日本心理学会第85回大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] PDE3阻害剤シロスタゾール：抗血小板薬から認知症治療薬へのドラッグ・リポジショニング2020
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  日本心理学会第84回大会，2020.9.8-11.2，Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] MAP kinase：ERK1／2遺伝子改変マウスを用いた小脳依存性記憶の解析2020
- Author(s)
  吉田彩乃、宮本武典、新崎智子、遠藤昌吾
- Organizer
  第72回日本動物学会・関東支部大会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] MAP kinase：ERK1／2遺伝子改変マウスを用いた小脳依存性記憶の解2020
- Author(s)
  吉田彩乃、宮本武典、新崎智子、遠藤昌吾
- Organizer
  第72回日本動物学会・関東支部大会,　Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Inhibitory effect of tocotrienols on weight gain in different mouse models.2020
- Author(s)
  Y. Kato, S. Endo, S. Yanai, K. Fukui.
- Organizer
  第43回日本基礎老化学会大会，誌上開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] MAP kinase：ERK1／2遺伝子改変マウスを用いた小脳依存性記憶の解析2020
- Author(s)
  吉田彩乃、宮本武典、新崎智子、遠藤昌吾
- Organizer
  第72回日本動物学会・関東支部大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of reactive oxygen species (ROS) - 8-nitro-cGMP signals in cerebellar long-term depression.2020
- Author(s)
  Kakizawa S., Endo S
- Organizer
  The 12th Forum of European Neuroscience, Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] 18F-標識ネオペンチルスチリルピリジンアミロイド-β PETプローブの生物学的評価．2020
- Author(s)
  多胡哲郎・豊原潤・ソウエイソウ・龍田真帆・新崎智子・柳井修一・遠藤昌吾・斉藤貴志・西道隆臣・田中浩士
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Ca2+とレドックスシグナルによる小脳シナプス可塑性の極性決定.2020
- Author(s)
  柿澤昌, 遠藤昌吾.
- Organizer
  生理学研究所研究会「細胞システム理解のためのシグナル応答原理解明の最前線」, Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Amelioration of age-related spatial memory impairment by concurrent administration of sub-effective doses of donepezil and cilostazol.2020
- Author(s)
  S. Yanai, T. Arasaki, S. Endo
- Organizer
  第43回日本基礎老化学会大会，誌上開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] The role of extracellular signal-regulated kinase (ERK) 5 in spinal cord on pathological pain in mice2020
- Author(s)
  Fumihiro Matsuura , Yasushi Satoh, Masanori Kawaguchi, Xin Wang, Shogo Endo,　Takehiko Ikeda
- Organizer
  Euroanaesthesia 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08878
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, ameliorates spatial memory in APP knock-in mouse model of Alzheimer’s disease.2020
- Author(s)
  S. Yanai, T. Arasaki, T. Saito, T. Saido, & S. Endo
- Organizer
  第43回日本神経科学大会, Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] 細胞外シグナル伝達キナーゼ(ERK)5が疼痛シグナル伝達経路に及ぼす影響2019
- Author(s)
  結城充正　渡邊智美　松浦史博　遠藤昌吾　佐藤泰司　池田健彦
- Organizer
  第66回日本麻酔科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08878
[Presentation] 細胞外シグナル制御キナーゼ(ERK)5の疼痛シグナル制御における役割2019
- Author(s)
  松浦史博, 板倉紗也子, 川口慎憲, 遠藤昌吾, 佐藤泰司, 石塚俊晶, 池田健彦
- Organizer
  第53回日本ペインクリニック学会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Concurrent administration of sub-effective doses of donepezil and phosphodiesterase 3 inhibitor cilostazol restores memory impairment in aged mice.2019
- Author(s)
  Shuichi YANAI, Tomoko Arasaki, Shogo Endo
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, improves blood-brain barrier integrity and ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8).2019
- Author(s)
  S.Yanai, T.Arasaki & S.Endo
- Organizer
  「次世代脳」プロジェクト冬のシンポジウム
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, improves blood-brain barrier integrity and ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8).2019
- Author(s)
  S.Yanai, T.Arasaki & S.Endo
- Organizer
  「次世代脳」プロジェクト冬のシンポジウム
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] レドックスシグナルによる小脳機能制御2019
- Author(s)
  柿澤昌, 遠藤昌吾
- Organizer
  生理学研究所研究会「シグナル動態の可視化と操作に基づく多階層機能解析の新展開」
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Amelioration of potentially harmful oxidative and nitrosative protein modifications by regular exercise in aged animals: A molecular mechanism of the beneficial effects2019
- Author(s)
  Sataro Goto, Shuo-wen Chang, Shohei Shinozaki, Shuichi Yanai, Hideko Nakamoto, Ayako Matsumoto, Hisashi Naito, Hiroyuki Kobayshi, Masao Kaneki, Shogo Endo, & Zsolt Radak
- Organizer
  11th International Association of Gerontology and Geriatrics Asia/Oceania Regional Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] PDE3阻害剤シロスタゾールによる血液脳関門・記憶機能の改善2019
- Author(s)
  柳井修一、新崎智子、遠藤昌吾
- Organizer
  第8回　TOBIRA研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of ROS - 8-nitro-cGMP signals in cerebellar long-term depression.2019
- Author(s)
  Sho Kakizawa, Shogo Endo
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of ROS - 8-nitro-cGMP signals in cerebellar long-term depression.2019
- Author(s)
  Sho Kakizawa, Shogo Endo
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Amelioration of potentially harmful oxidative and nitrosative protein modifications by regular exercise in aged animals: A molecular mechanism of the beneficial effects2019
- Author(s)
  Sataro Goto, Shuo-wen Chang, Shohei Shinozaki, Shuichi Yanai, Hideko Nakamoto, Ayako Matsumoto, Hisashi Naito, Hiroyuki Kobayshi, Masao Kaneki, Shogo Endo, & Zsolt Radak
- Organizer
  11th International Association of Gerontology and Geriatrics Asia/Oceania Regional Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] 有酸素トレーニングが老齢マウス脳内のインスリン分解酵素のS-ニトロソ化に及ぼす影響2019
- Author(s)
  張碩文・篠崎昇平・柳井修一・松本綾子・中本英子・小林裕幸・金木正夫・遠藤昌吾・後藤佐多良・内藤久士
- Organizer
  第74回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] レドックスシグナルによる小脳機能制御2019
- Author(s)
  柿澤昌, 遠藤昌吾
- Organizer
  生理学研究所研究会「シグナル動態の可視化と操作に基づく多階層機能解析の新展開」
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] 有酸素トレーニングが老齢マウス脳内のインスリン分解酵素のS-ニトロソ化に及ぼす影響2019
- Author(s)
  張碩文・篠崎昇平・柳井修一・松本綾子・中本英子・小林裕幸・金木正夫・遠藤昌吾・後藤佐多良・内藤久士
- Organizer
  第74回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] 細胞外シグナル制御キナーゼ(ERK)5の疼痛シグナル制御における役割2019
- Author(s)
  松浦史博, 板倉紗也子, 川口慎憲, 遠藤昌吾, 佐藤泰司, 石塚俊晶, 池田健彦
- Organizer
  第53回日本ペインクリニック学会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] PDE3阻害剤シロスタゾールによる血液脳関門・記憶機能の改善2019
- Author(s)
  柳井修一、新崎智子、遠藤昌吾
- Organizer
  第8回　TOBIRA研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Concurrent administration of sub-effective doses of donepezil and phosphodiesterase 3 inhibitor cilostazol restores memory impairment in aged mice.2019
- Author(s)
  Shuichi YANAI, Tomoko Arasaki, Shogo Endo
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] 細胞外シグナル制御キナーゼ(ERK) 5の疼痛シグナル制御における役割2019
- Author(s)
  松浦史博　板倉紗也子　川口慎憲　遠藤昌吾　佐藤泰司　池田健彦
- Organizer
  第8回北関東・甲信越ペインクリニック学会
- Data Source
  KAKENHI-PROJECT-18K08878
[Presentation] 活性酸素シグナルによる小脳シナプス機能制御2018
- Author(s)
  柿澤昌、遠藤昌吾
- Organizer
  生理研研究会「シグナル動態の可視化と操作に基づく多階層機能解析の新展開」
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Involvement of ROS/8-nitro-cGMP signals in cerebellar synaptic plasticity in mice.2018
- Author(s)
  S.Kakizawa, S.Endo.
- Organizer
  World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, maintains and improves memory functions in aged mice.2018
- Author(s)
  S.Yanai, T.Arasaki & S.Endo
- Organizer
  Society for Neuroscience Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] The phosphodiesterase 3 inhibitor cilostazol restores memory impairment and enhances cerebral glucose metabolism in aged mice.2018
- Author(s)
  S.Yanai, T.Tago, J.Toyohara, T.Arasaki & S.Endo
- Organizer
  日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Recovery from spatial memory deficits and increase of cerebral glucose uptake in cilostazol-administered aged mice.2018
- Author(s)
  S.Yanai, T.Tago, J.Toyohara, T.Arasaki & S.Endo.
- Organizer
  第41回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, improves blood-brain barrier integrity and ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8).2017
- Author(s)
  S.Yanai, J.Toyohara, K.Ishiwata, T.Arasaki S.Endo.
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Cilostazol administration ameliorates the impaired conditioned fear in senescence-accelerated mouse prone 8 (SAMP8).2017
- Author(s)
  S.Yanai, T.Arasaki, S.Endo.
- Organizer
  第40回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] cAMP系増強薬と記憶障害の治療―既存薬再開発の応用―2017
- Author(s)
  遠藤昌吾
- Organizer
  OYC　バイオシンポジウム　「老化と加齢性疾患」
- Invited
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] シロスタゾール投与マウスを用いたPRECISEによる行動解析.2017
- Author(s)
  柳井修一、新崎智子、遠藤昌吾
- Organizer
  TOBIRA第6回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] The effect of 8-nitro-cGMP on SNARE complex assembly and memory2017
- Author(s)
  Y.Kishimoto, S.Yanai, S.Endo, T.Akaike, H.Ihara.
- Organizer
  第60回日本神経化学大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Preclinical and first-in-man studies of imidazopyridineacetamide, [11C]CB184, as a novel 18 kDa translocator protein seeker.2016
- Author(s)
  Jun Toyohara, Muneyuki Sakata, Kenji Ishibashi, Kei Wagatsuma, Kentaro Hatano, Shuichi Yanai, Shogo Endo, Kenji Ishii and Kiichi Ishiwata.
- Organizer
  Society of nuclear medicine and molecular imaging 2016 annual meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2016-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Up-regulation of NSP3 by oligomeric Abeta; accelerates neuronal death through Cas-independent Rap1A activation.2016
- Author(s)
  五味不二也・遠藤昌吾・内田洋子
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 老化に伴う認知機能低下に対するシロスタゾールとドネペジルの併用効果2016
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  第39回日本基礎老化学会大会
- Place of Presentation
  伊勢原市民文化会館（神奈川県伊勢原市）
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 8-nitro-cGMP on hippocampus-dependent long-term memory in mice.2016
- Author(s)
  Yusuke Kishimoto, Suhichi Yanai, Shogo Endo, Takaaki Akaike, & Hideshi Ihara.
- Organizer
  The 9th International Conference on the Bilogy, Chemisty, and Therapeutic Application of Nitric Oxide
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 老化促進モデルマウスSAMP8における記憶、学習機能の評価2016
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  第31回SAM研究発表会
- Place of Presentation
  京都大学芝蘭会館（京都府京都市）
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 8-ニトロ-cGMPによるホスホジエステラーゼの阻害効果2016
- Author(s)
  遠藤昌吾、新崎智子、藤井重元、赤池孝章
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, as a potential therapeutic target for the treatment of dementia.2016
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo.
- Organizer
  31st International Congress of Psychology
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Long-term administration of cilostazol, a phosphodiesterase 3 inhibitor, enhances memory functions and cerebral glucose metabolism in aged mice2016
- Author(s)
  柳井修一・豊原潤・石渡喜一・新崎智子・遠藤昌吾
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 東日本大震災が引き起こしたマウスの行動変化2015
- Author(s)
  遠藤昌吾
- Organizer
  第９０回実験動物コンファレンス
- Place of Presentation
  日本獣医生命科学大学（東京、武蔵野市）
- Year and Date
  2015-06-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] ATTACKING MEMORY DECLINE THROUGH THE KNOWLEDGE OF SIGNAL TRANSDUCTION PATHWAY2015
- Author(s)
  S. Endo
- Organizer
  IAGG2015
- Place of Presentation
  Chiang Mai Convention and Exhibition Center (Chiang Mai, Thailand)
- Year and Date
  2015-10-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] 東日本大震災が引き起こしたマウスの行動変化2015
- Author(s)
  遠藤昌吾
- Organizer
  第９０回実験動物コンファレン
- Place of Presentation
  日本獣医生命科学大学（東京、武蔵野市）
- Year and Date
  2015-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 行動解析を用いたホスホジエステラーゼ3阻害剤シロスタゾールの記憶改善効果の評価2015
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  首都大学東京バイオコンファレンス2015
- Place of Presentation
  首都大学東京（八王子市、東京）
- Year and Date
  2015-11-06
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] 老化に伴う認知機能低下に対するホスホジエステラーゼ3阻害剤cilostazolの効果2015
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  第38回日本基礎老化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川、横浜）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] MP30/αTTP-ダブルノックアウトマウスを用いたアスコルビン酸およびα-トコフェロール欠乏が及ぼす不安、学習、運動機能への影響2015
- Author(s)
  高橋経太・柳井修一・下門顕太郎・遠藤昌吾・新井洋由・石神昭人
- Organizer
  日本心理学会第79回大会
- Place of Presentation
  名古屋国際会議場（愛知、名古屋）
- Year and Date
  2015-09-22
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 行動解析を用いたホスホジエステラーゼ3阻害剤シロスタゾールの記憶改善効果の評価2015
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  首都大学東京バイオコンファレンス２０１５
- Place of Presentation
  首都大学東京（東京、八王子）
- Year and Date
  2015-11-06
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] ATTACKING MEMORY DECLINE THROUGH THE KNOWLEDGE OF SIGNAL TRANSDUCTION PATHWAY2015
- Author(s)
  S. Endo
- Organizer
  IAGG2015
- Place of Presentation
  Chiang Mai International Convention and Exhibition Center(ChiangMai, Thailand)
- Year and Date
  2015-10-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 老化に伴う認知機能低下に対するホスホジエステラーゼ3阻害剤cilostazolの効果2015
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  第38回日本基礎老化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川、横浜）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Long-term administration of cilostazol, a phosphodiesterase 3 inhibitor, prevents memory decline in aged mice models.2015
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際展示場（兵庫、神戸）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Long-term administration of cilostazol, a phosphodiesterase 3 inhibitor, prevents memory decline in aged mice models.2015
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫、神戸）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] SMP30/αTTP-ダブルノックアウトマウスを用いたアスコルビン酸およびα-トコフェロール欠乏が及ぼす不安、学習、運動機能への影響2015
- Author(s)
  高橋経太・柳井修一・下門顕太郎・遠藤昌吾・新井洋由・石神昭人
- Organizer
  日本心理学会第79回大会
- Place of Presentation
  名古屋国際会議場（愛知、名古屋）
- Year and Date
  2015-09-22
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] 記憶改善薬のスクリーニングとSAM2014
- Author(s)
  遠藤昌吾
- Organizer
  第２９回SAM研究協議会研究発表会
- Place of Presentation
  東京都健康長寿医療センター（板橋区、東京）
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] Phosphodiesterase 3 inhibitor cilostazol improves conditioned fear in SAM-P8 mice.2014
- Author(s)
  S. Yanai, K Kojima, T. Arasaki, and S. Endo.
- Organizer
  Annual meeting of Japan Society for Biomedical Gerontology
- Place of Presentation
  あいち健康プラザ（愛知、大府）
- Year and Date
  2014-07-26
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] Maintenance of memory functions by chronic administration of cilostazol, a phosphodiesterase 3 inhibitor, in aged mice models.2014
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo.
- Organizer
  Neuroscience 2014
- Place of Presentation
  Washignton Convention Center (Washington DC, USA)
- Year and Date
  2014-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] 記憶改善薬のスクリーニングとSAM2014
- Author(s)
  遠藤昌吾
- Organizer
  SAM研究協議会研究発表会
- Place of Presentation
  東京
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Allodynia is reduced in mice deficient for ERK2.2014
- Author(s)
  Y. Satoh, Y. Otsubo, G. Pagès, J. Pouysségur, S. Endo, T. Kazama.
- Organizer
  2014
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] PDE3阻害剤シロスタゾールによる老化促進モデルマウスの記憶障害改善効果2014
- Author(s)
  柳井修一・小島開・新崎智子・遠藤昌吾
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川、横浜）
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] Deficits in working memory related to obstacle avoidance during locomotion in Alzheimer’s disease mutant mice.2013
- Author(s)
  S. Setogawa, H. Yamaura, S. Endo, D. Yanagihara.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Distribution of 8-nitro-cGMP and S-guanylated proteins in cerebellum.2013
- Author(s)
  S. Endo, M. Nakamura,T. Arasaki,T. Akaike
- Organizer
  Japan Neuroscience Society
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Annormal pain in mice deficient for ERK2 in the central nervous system.2013
- Author(s)
  Y. Otsubo-iwama, Y. Satoh, S.Endo, G. Pages, J. Pouysegur, T. Yamamoto, Y. Takahashi, T. Kazama
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Deep cerebellar nuclei play an important role in two-tone discrimination on delay eyeblink conditioning in C57BL/6 mice.2013
- Author(s)
  T. Sakamoto, S. Endo.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Deletion of hepatic ERK2 decreased the SERCA2 expressions, which can account for vascular oxidative stress and endothelial dysfunction in metabolic stress.2013
- Author(s)
  T. Adachi, T. Nanba, Y. Satoh, M. Ayaori, Y. Shiraishi, Y.Arai-Nakaya, D. Hakuno, H. Yada, K. Isoda, S. Endo, T. Kujiraoka
- Organizer
  11th International symposium on mechanisms on vasodilation,
- Place of Presentation
  Zurich, Switzerland
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Abnormal neuropathic pain in mice deficient for ERK2 in the central nervous system.2013
- Author(s)
  Otsubo Y., Satoh Y., Kodama M., Araki Y., Satomoto M., Sakamoto E., Pages G., Pouyssegur J., Endo S., Kazama T.
- Organizer
  8th “Pain in Europe” Congress
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Deletion of hepatic ERK2 decreased the SERCA2 expressions, which can account for vascular oxidative stress and endothelial dysfunction in metabolic stress2013
- Author(s)
  Adachi T., Nanba T., Satoh Y., Ayaori M., Shiraishi Y., Arai-Nakaya Y., Endo S., Hakuno D., Yada H., Isoda K.,Endo S., Kujiraoka T
- Organizer
  11th International sumposium on mechanisms of vasolidation (MOVD 2013)
- Place of Presentation
  チューリッヒ、スイス
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Cilostazol, a PDE3 inhibitor, improves learning and memory in mice.2013
- Author(s)
  S. Yanai, Y. Semba, S. Endo.
- Organizer
  Japan Neuroscience Society
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Hepatic ERK2 deficiency develops hepatosteatosis with decreased expression of SERCA2, which can account for metabolic remodeling and endothelial dysfunction2012
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M., Shiraishi Y., Nakaya Y., Endo S., Hakuno D., Isoda K., Adachi T
- Organizer
  米国心臓病学会議2012(AHA 2012)
- Place of Presentation
  ロサンゼルス、米国
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Hepatic ERK suppresses endothelial dysfunction with the alleviation of hepatosteatosis and metabolic remodeling in mice fed high-fat and high-sucrose diet2012
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M., Shiraishi Y., Nakaya Y., Endo S., Hakuno D., Isoda K., Adachi T
- Organizer
  欧州心臓学会議2012(ESC2012)
- Place of Presentation
  ミュンヘン、ドイツ
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Mechanical allodynia but not thermal hyperalgesia is impaired in mice deficient for ERK2 in the central nervous system2012
- Author(s)
  Otsubo Y., Satoh Y., Kodama M., Araki Y., Endo S, Kazama T
- Organizer
  世界疼痛学会2012(IASP 2012)
- Place of Presentation
  ミラノ、イタリア
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Hepatic ERK protects from endothelial dysfunction with the suppression of hepatic steatosis in mice fed high-fat and high-sucrose diet2011
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M, Hakuno D., Endo S., Niida T., Isoda K., Adachi T
- Organizer
  第84回米国心臓協会学術集会
- Place of Presentation
  オーランド, 米国
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Maintenance of memory functions by chronic administration of cilostazol, a phosphodiesterase 3 inhibitor, in aged mice models.
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo
- Organizer
  Annual meeting of Society for Neuroscience
- Place of Presentation
  Washignton D.C., USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Cilostazol,a phosphodiesterase 3 inhibitor, improves memories in senescence accelerated mice.
- Author(s)
  S. Yanai, T. Arasaki, and S. Endo.
- Organizer
  Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Phosphodiesterase 3 inhibitor cilostazol improves conditioned fear in SAM-P8 mice.
- Author(s)
  S. Yanai, K Kojima, T. Arasaki, and S. Endo.
- Organizer
  Annual meeting of Japan Society for Biomedical Gerontology
- Place of Presentation
  Obu, Aichi, Japan
- Year and Date
  2014-07-26 – 2014-07-27
- Data Source
  KAKENHI-PROJECT-25560382

1. SATOH Yasushi (10505267)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. IKEDA Toshio (80252526)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 柿澤昌 (40291059)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. YANAI Shuichi (60469070)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
5. ADACHI Takeshi (50231931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. ARASAKI Tomoko (90645855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
7. 池田健彦 (10262817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. KAZAMA TOMIEI (40158837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Kojima Nobuhiko (80215251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. LAUNEY Thomas (30322704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. Masanori Kawaguchi (60614633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 平井宏和 (70291086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 苅谷研一 (40263371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 海川正人 (00325838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 武居公子 (90325861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 神尾陽子 (00252445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 照井克生 (90256074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 鈴木康之 (60179265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 中田隆博 (40273932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 柳原大 (90252725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 後藤典子 (10251448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 福田敦夫 (50254272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 菱木貴子 (10338022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 高橋哲也 (00589905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TAKISHIMA Kunio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ISHIZUKA Toshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. TOYOHARA Jun

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 野村さやか

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 中野裕康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 佐藤貴浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 坂本敏郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 坂本浩隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 山崎創

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 石渡喜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 荒木幸仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 塩谷彰浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 鈴木匡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 鈴木道雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 阪上洋行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 藤岡正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Endo Shogo 遠藤 昌吾

ENDO Shogo 遠藤 昌吾

遠藤 省吾 エンドウ ショウゴ

遠藤 昌吾 エンドウ ショウゴ

Research Projects

Research Products

Co-Researchers

Aging cerebellum and cognitive declinePrincipal Investigator

Principal Investigator

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Cognitive impairment viewed from the aging cerebellumPrincipal Investigator

Principal Investigator

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Review Section

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Principal Investigator

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Principal Investigator

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Roles of 8-nitro-cGMP pathway as the coincident detector for memory formation.Principal Investigator

Principal Investigator

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Reactive oxygen species; physiological role in the brainPrincipal Investigator

Principal Investigator

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Association of cognitive frailty and signal transduction disfunction.Principal Investigator

Principal Investigator

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Principal Investigator

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Motor memory and anti-oxidant agentsPrincipal Investigator

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Principal Investigator

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Principal Investigator

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活性酸素種が担うマウス運動記憶の分散効果Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

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Principal Investigator

Project Period (FY)

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Research Institution

Mechanisms underlying spacing effect of memoryPrincipal Investigator

Endo Shogo 遠藤昌吾

ENDO Shogo 遠藤昌吾

遠藤省吾エンドウショウゴ

遠藤昌吾エンドウショウゴ

[Book] Clinical　Neuroscience2013

[Book] Clinical　Neuroscience2013