Endo Shogo 遠藤昌吾

… Alternative Names

ENDO Shogo 遠藤昌吾

遠藤省吾エンドウショウゴ

遠藤昌吾エンドウショウゴ

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Researcher Number	60192514
Other IDs	https://orcid.org/0000-0002-3948-8723
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長
Affiliation (based on the past Project Information) *help	2013 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 2013 – 2016: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), その他部局等, その他 2014 – 2015: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究部長 2012: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 老化脳神経科学研究チーム, 研究部長 2012: 地方独立行政法人東京都健康長寿医療センター研究所, 老化制御研究チーム, 研究部長 … More 2011: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究部長 2010: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 研究部長 2006 – 2007: 沖縄科学技術研究基盤整備機構, 記憶と学習の分子神経生物学ユニット, 代表研究者 2004: RIKEN, Research Unit, Unit Leader, 遠藤研究ユニット, ユニットリーダー 2003: 独立行政法人理化学研究所, 神経回路メカニズム研究グループ, 上級研究員 2001 – 2002: Neuronal Circuit Mechanism Research Group, RIKEN Senior Scientist, 神経回路メカニズム研究グループ, 上級研究員 2000: 理化学研究所, 神経回路メカニズム研究グルーブ, 上級研究員 1998 – 2000: 理化学研究所, 記憶学習機構研究チーム, 研究員 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Neuroscience in general / Basic Section 59040:Nutrition science and health science-related / Applied health science / Biological Sciences / Biological Sciences Except Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology / Neurochemistry/Neuropharmacology / Neuroscience in general / Biological Sciences
Keywords	Principal Investigator 小脳 / 記憶 / 一酸化窒素 / cGMP / 8-ニトロ-cGMP / 活性酸素種 / LTD / プルキンエ細胞 / 認知機能 / ROS … More / 長期抑圧 / 遺伝子欠損マウス / 学習 / 老化 / 加齢 / Nitric oxide / ERK / プロテアーゼ / CCAS / 老廃物除去 / 可塑性 / 記憶・学習 / シグナル伝達 / 連合性 / PKG / 連合性検出器 / ホスホジエステラーぜ / バイオマーカー / 握力 / 遺伝子改変マウス / AMP / マウス / 包括的行動解析 / 認知的フレイル / 炎症 / cAMP / シロスタゾール / フレイル / 注意 / 身体機能 / NO / LTP/LTD / 神経可塑性 / 運動記憶 / 8-nitro-cGMP / ビタミン / 長期記憶 / 運動学習 / ビタミンE / アスコルビン酸 / 運動 / 分散効果 / gene deficient mice / nuclear translocation / MAP kinase / IoxP / Cre / loxP / ERK2 / Cre-LoxP / 核内移行 / MAPキナーゼ / Synaptic transmission / Cerebellum / プロテインホスファターゼ / G-substrate / 神経伝達 / 分散学習 / 休憩 / グアニル化 / 眼球運動 / リハビリテーション / MEK / MAPK / プロテアソーム / カルパイン / 記憶学習 … More Except Principal Investigator 細胞内情報伝達 / ERK / ノックアウトマウス / 神経毒性 / 全身麻酔薬 / 自閉症 / 疼痛 / セボフルラン / ＥＲＫ / 臨界期 / 神経発達 / 発達 / 小児 / 麻酔 / マウス / 発達期 / 神経 / 感作 / 代謝 / 神経障害性疼痛 / 炎症性疼痛 / ERK1 / 脊髄 / 中枢性感作 / ERK5 / ERK2 / アポトーシス / 神経回路 / 吸入麻酔薬 / sevoflurane / mouse / toxicity / developing brain / apoptosis / general anesthetics / 転写調節因子 / 海馬ニューロン / 神経突起 / cAMP / 最初期遺伝子 / CRE転写調節 / 樹状突起スパイン / 突起伸長 / PC12細胞 / 遺伝子発現 / シナプス可塑性 / 行動実験 / 脳 / 母性行動 / 水素 / 記憶・学習 / 育児 / 分化・増殖 / 神経幹細胞 / 極性異常 / 上皮細胞 / がん細胞 / MAP4K / Rap2 / シグナル伝達 / 癌 Less

Aging cerebellum and cognitive declinePrincipal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Cognitive impairment viewed from the aging cerebellumPrincipal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
慢性疼痛発症におけるERK細胞内情報伝達機構の役割
- Principal Investigator
  
  高橋哲也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  National Defense Medical College
発達期の脳における全身麻酔薬の神経毒性メカニズムの解明
- Principal Investigator
  
  佐藤泰司
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  National Defense Medical College
Roles of 8-nitro-cGMP pathway as the coincident detector for memory formation.Principal Investigator
- Principal Investigator
  
  Endo Shogo
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Reactive oxygen species; physiological role in the brainPrincipal Investigator
- Principal Investigator
  
  Endo Shogo
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Association of cognitive frailty and signal transduction disfunction.Principal Investigator
- Principal Investigator
  
  Endo Shogo
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
The role of extracellular signal-regulated kinase (ERK) in pathological pain
- Principal Investigator
  
  Masanori Kawaguchi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  National Defense Medical College
Motor memory and anti-oxidant agentsPrincipal Investigator
- Principal Investigator
  
  Endo Shogo
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Effects of general anesthetics on the regulatory mechanisms of neuronal development in the critical period
- Principal Investigator
  
  SATOH YASUSHI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  National Defense Medical College
Screening of molecules responsible for signaling from nucleus to synapses in emotional memory
- Principal Investigator
  
  Kojima Nobuhiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Toyo University
活性酸素種が担うマウス運動記憶の分散効果Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Neurotoxicity of general anesthetics in the developing brain
- Principal Investigator
  
  KAZAMA TOMIEI
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  National Defense Medical College
Mechanisms underlying spacing effect of memoryPrincipal Investigator
- Principal Investigator
  
  ENDO Shogo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Study for the Function of ERK2 in the Brain Using ERK2 Conditional Knockout Mouse
- Principal Investigator
  
  SATOH Yasushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  防衛医科大学校
   National Defense Medical College
低分子量G蛋白質Rap2とがん細胞の分化異常
- Principal Investigator
  
  苅谷研一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of the Ryukyus
Comprehensive examination of physiological role of ERK2 in neuronal cells.Principal Investigator
- Principal Investigator
  
  ENDO Shogo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  RIKEN
小脳の神経可塑性に関与するNOカスケードの研究Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
脳内NOカスケード構成因子G-substrate欠損マウスの解析Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Studies on the nitric oxide cascade involved in neuronal plasticity.Principal Investigator
- Principal Investigator
  
  ENDO Shogo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  RIKEN
シナプス可塑性に関与するプロテアーゼに関する研究Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The Institute of Physical and Chemical Research
記憶の維持に関与するプロテアーゼの研究Principal Investigator
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research

[Book] Clinical　Neuroscience2013
- Author(s)
  遠藤昌吾
- Total Pages
  97
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25293331
[Book] Brain Aging and Therapeutic Interventions (Thakur and Rattan Ed.)2013
- Author(s)
  Shogo Endo
- Total Pages
  296
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25560382
[Book] Clinical　Neuroscience2013
- Author(s)
  佐藤泰司、遠藤昌吾
- Total Pages
  97
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25293331
[Journal Article] Essential role of ROS - 8-Nitro-cGMP signaling in long-term memory of motor learning and cerebellar synaptic plasticity2024
- Author(s)
  Kakizawa Sho、Arasaki Tomoko、Yoshida Ayano、Sato Ayami、Takino Yuka、Ishigami Akihito、Akaike Takaaki、Yanai Shuichi、Endo Shogo
- Journal Title
  
  Redox Biology
  
  Volume: 70 Pages: 103053-103053
- DOI
  10.1016/j.redox.2024.103053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K18456, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-23K06012, KAKENHI-PROJECT-21K17697, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277
[Journal Article] Cerebellum － Potential Therapeutic Target for Cognitive Impairment2024
- Author(s)
  Sho Kakizawa, Shogo Endo
- Journal Title
  
  BIO Clinica
  
  Volume: 39 Pages: 39-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18456
[Journal Article] Metabolic Remodeling with Hepatosteatosis Induced Vascular Oxidative Stress in Hepatic ERK2 Deficiency Mice with High Fat Diets2022
- Author(s)
  Kujiraoka Takehiko、Kagami Kazuki、Kimura Toyokazu、Ishinoda Yuki、Shiraishi Yasunaga、Ido Yasuo、Endo Shogo、Satoh Yasushi、Adachi Takeshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8521-8521
- DOI
  10.3390/ijms23158521
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752, KAKENHI-PROJECT-20K17204
[Journal Article] Reversal of spatial memory impairment by phosphodiesterase 3 inhibitor cilostazol is associated with reduced neuroinflammation and increased cerebral glucose uptake in aged male mice2022
- Author(s)
  Yanai Shuichi、Tago Tetsuro、Toyohara Jun、Arasaki Tomoko、Endo Shogo
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 1031637-1031637
- DOI
  10.3389/fphar.2022.1031637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07663, KAKENHI-PROJECT-22K11872, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Study of aging using circuit tests and parametric analysis2022
- Author(s)
  Konishi Tomokazu、Yanai Shuichi、Endo Shogo
- Journal Title
  
  bioRxiv,
  
  Volume: 1 Pages: 1-1
- DOI
  10.1101/2022.03.24.485723
- Open Access
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] Endothelial Extracellular Signal‐Regulated Kinase/Thromboxane A2/Prostanoid Receptor Pathway Aggravates Endothelial Dysfunction and Insulin Resistance in a Mouse Model of Metabolic Syndrome2022
- Author(s)
  Sato Atsushi、Yumita Yusuke、Kagami Kazuki、Ishinoda Yuki、Kimura Toyokazu、Osaki Ayumu、Toya Takumi、Namba Takayuki、Endo Shogo、Ido Yasuo、Nagatomo Yuji、Satoh Yasushi、Adachi Takeshi
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 11 Issue: 23
- DOI
  10.1161/jaha.122.027538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Long-term D-Allose Administration Favorably Alters the Intestinal Environment in Aged Male Mice2022
- Author(s)
  Tomoya Shintani, Shuichi Yanai, Akane Kanasaki, Misuzu Tanaka, Tetsuo Iida, Genki Ozawa, Tadao Kunihiro, & Shogo Endo
- Journal Title
  
  Journal of Applied Glycoscience
  
  Volume: 69 Issue: 4 Pages: 97-102
- DOI
  10.5458/jag.jag.JAG-2022_0005
- ISSN
  1344-7882, 1880-7291
- Year and Date
  2022-11-20
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11872, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] 細胞のメカニズムと神経疾患：細胞内シグナル伝達の基礎①, ERK2022
- Author(s)
  佐藤泰司,遠藤昌吾
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 70 Pages: 814-816
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] 細胞のメカニズムと神経疾患：細胞内シグナル伝達の基礎①, ERK2022
- Author(s)
  佐藤泰司,遠藤昌吾
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 70 Pages: 814-816
- Data Source
  KAKENHI-PROJECT-21K19752
[Journal Article] Extracellular signal‐regulated kinases 2 (Erk2) and Erk5 in the central nervous system differentially contribute to central sensitization in male mice2021
- Author(s)
  Matsuura Fumihiro、Satoh Yasushi、Itakura Sayako、Morohashi Toru、Kawaguchi Masanori、Takahashi Tetsuya、Iwanaga Koji、Terashima Hayato、Kobayashi Yasushi、Wang Xin、Ishizuka Toshiaki、Endo Shogo、Ikeda Takehiko
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 99 Issue: 6 Pages: 1666-1688
- DOI
  10.1002/jnr.24827
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11548, KAKENHI-PROJECT-18K08878, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752, KAKENHI-PROJECT-21K16555
[Journal Article] Role of G-Substrate in the NO/cGMP/PKG Signal Transduction Pathway for Photic Entrainment of the Hamster Circadian Clock2021
- Author(s)
  Plano Santiago Andr?s、Alessandro Mar?a Soledad、Trebucq Laura Luc?a、Endo Shogo、Golombek Diego Andr?s、Chiesa Juan Jos?
- Journal Title
  
  ASN Neuro
  
  Volume: 13 Issue: 1 Pages: 175909142098492-175909142098492
- DOI
  10.1177/1759091420984920
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Tocotrienols reach the brain and play roles in the attenuation of body weight gain and improvement of cognitive function in high-fat diet-treated mice2021
- Author(s)
  Kato Yugo、Uchiumi Hayami、Usami Ryo、Takatsu Hirokatsu、Aoki Yoshinori、Yanai Shuichi、Endo Shogo、Fukui Koji
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 69 Issue: 3 Pages: 256-264
- DOI
  10.3164/jcbn.21-10
- NAID
  130008110247
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Functional Aging in Male C57BL/6J Mice Across the Life-Span: A Systematic Behavioral Analysis of Motor, Emotional, and Memory Function to Define an Aging Phenotype2021
- Author(s)
  Yanai Shuichi、Endo Shogo
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 13 Pages: 697621-697621
- DOI
  10.3389/fnagi.2021.697621
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Central, but not peripheral, nervous ERK2 is essential for itch signals in murine allergic skin inflammation.2021
- Author(s)
  Matsuo S, Hashimoto T, Matsuura F, Imamura O, Endo S, Satoh Y, Satoh T.
- Journal Title
  
  Allergy
  
  Volume: 76 Issue: 11 Pages: 3422-3432
- DOI
  10.1111/all.14867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08805, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
[Journal Article] Inhibition of extracellular signal-regulated kinase pathway suppresses tracheal stenosis in a novel mouse model2021
- Author(s)
  Kimura Akari、Araki Koji、Satoh Yasushi、Mogi Sachiyo、Fujitani Kazuko、Kurioka Takaomi、Endo Shogo、Shiotani Akihiro、Yamashita Taku
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 9 Pages: 0256127-0256127
- DOI
  10.1371/journal.pone.0256127
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09390, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752, KAKENHI-PROJECT-19K18782, KAKENHI-PROJECT-20K18263
[Journal Article] 記憶を守る2020
- Author(s)
  遠藤昌吾
- Journal Title
  
  内藤財団時報
  
  Volume: 105 Pages: 37-37
- Data Source
  KAKENHI-PROJECT-19K22834
[Journal Article] 認知症と老化に伴う記憶低下の予防と制御―細胞内シグナル伝達系を標的として―2020
- Author(s)
  柳井修一・遠藤昌吾
- Journal Title
  
  医学のあゆみ
  
  Volume: 273 Pages: 1095-1101
- Data Source
  KAKENHI-PROJECT-19K22834
[Journal Article] 認知症と老化に伴う記憶低下の予防と制御―細胞内シグナル伝達系を標的として― Prevention and control of age-related memory decline and dementia2020
- Author(s)
  柳井修一、遠藤昌吾
- Journal Title
  
  医学のあゆみ
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] 神経細胞レベルのシナプス可塑性（海馬と小脳におけるシナプス可塑性）2020
- Author(s)
  遠藤昌吾
- Journal Title
  
  ヒトの動きの神経科学シリーズ-IV- 運動学習の脳・神経科学（大築、鈴木、柳原編集）
  
  Volume: 4 Pages: 20-39
- Data Source
  KAKENHI-PROJECT-19K22834
[Journal Article] 記憶を守る2020
- Author(s)
  遠藤昌吾
- Journal Title
  
  内藤財団時報
  
  Volume: 105 Pages: 105-105
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] Induction of ICER is superseded by smICER, challenging the impact of ICER under chronic beta‐adrenergic stimulation2020
- Author(s)
  Seidl Matthias D.、Fels Benedikt、Kranick Daniel、Sternberg Alexandra、Grimm Kristina、St?mpel Frank T.、Pluteanu Florentina、Schulte Jan S.、Heinick Alexander、Kojima Nobuhiko、Endo Shogo、Huge Andreas、Stoll Monika、M?ller Frank U.
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 8 Pages: 11272-11291
- DOI
  10.1096/fj.201902301rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-19H04044
[Journal Article] モデルマウスを用いた記憶障害メカニズムの解析2019
- Author(s)
  遠藤昌吾
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 859-863
- NAID
  130007700026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22834
[Journal Article] モデルマウスを用いた記憶障害メカニズムの解析2019
- Author(s)
  遠藤昌吾
- Journal Title
  
  ファルマシア
  
  Volume: 55 Pages: 859-863
- NAID
  130007700026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04044
[Journal Article] JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling2019
- Author(s)
  Katagiri Takaharu、Yamazaki Soh、Fukui Yuto、Aoki Kotaro、Yagita Hideo、Nishina Takashi、Mikami Tetuo、Katagiri Sayaka、Shiraishi Ayako、Kimura Soichiro、Tateda Kazuhiro、Sumimoto Hideki、Endo Shogo、Kameda Hideto、Nakano Hiroyasu
- Journal Title
  
  Mucosal Immunology
  
  Volume: 12 Issue: 5 Pages: 1104-1117
- DOI
  10.1038/s41385-019-0182-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07516, KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-17K08994, KAKENHI-PROJECT-19K07391
[Journal Article] 8-Nitro-cGMP attenuates context-dependent fear memory in mice.2019
- Author(s)
  Kishimoto Y, Kasamatsu S, Yanai S, Endo S, Akaike T, Ihara H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 511 Issue: 1 Pages: 141-147
- DOI
  10.1016/j.bbrc.2019.01.138
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-17K17583, KAKENHI-PROJECT-18K07460, KAKENHI-PROJECT-19K22834, KAKENHI-PROJECT-19H04044
[Journal Article] Up-regulation of NSP3 by Oligomeric Aβ Accelerates Neuronal Death Through Cas-independent Rap1A Activation2018
- Author(s)
  Gomi Fujiya、Uchida Yoko、Endo Shogo
- Journal Title
  
  Neuroscience
  
  Volume: 386 Pages: 182-193
- DOI
  10.1016/j.neuroscience.2018.06.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] PDE3 Inhibitors Repurposed as Treatments for Age-Related Cognitive Impairment2018
- Author(s)
  Yanai Shuichi、Endo Shogo
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 印刷中 Issue: 6 Pages: 4306-4316
- DOI
  10.1007/s12035-018-1374-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-18K07460
[Journal Article] Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages2018
- Author(s)
  Bohn T、Rapp S、Luther N、Klein M、Bruehl T-J、Kojima N、Aranda L P、Hahlbrock J、Muth S、Endo S、Pektor S、Brand A、Renner K、Popp V、Gerlach K、Vogel D、Lueckel C、Arnold-Schild D、Pouyssegur J、Kreutz M、Huber M、Koenig J、Weigmann B、Probst H-C、von Stebut E、Becker C、Schild H、Schmitt E、Bopp T
- Journal Title
  
  Nature Immunology
  
  Volume: 19 Issue: 12 Pages: 1319-1329
- DOI
  10.1038/s41590-018-0226-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] The role of Purkinje cell-derived VEGF in cerebellar astrogliosis in Niemann-Pick type C mice2018
- Author(s)
  Park Min Hee、Lee Ju Youn、Jeong Min Seock、Jang Hyung Sup、Endo Shogo、Bae Jae-sung、Jin Hee Kyung
- Journal Title
  
  BMB Reports
  
  Volume: 51 Issue: 2 Pages: 79-84
- DOI
  10.5483/bmbrep.2018.51.2.168
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Long-term cilostazol administration prevents age-related decline of hippocampus-dependent memory in mice2018
- Author(s)
  Yanai Shuichi、Ito Hideki、Endo Shogo
- Journal Title
  
  Neuropharmacology
  
  Volume: 129 Pages: 57-68
- DOI
  10.1016/j.neuropharm.2017.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] The AP-1 transcription factor JunB is required for Th17 cell differentiation2017
- Author(s)
  Yamazaki Soh、Tanaka Yoshihiko、Araki Hiromitsu、Kohda Akira、Sanematsu Fumiyuki、Arasaki Tomoko、Duan Xuefeng、Miura Fumihito、Katagiri Takaharu、Shindo Ryodai、Nakano Hiroyasu、Ito Takashi、Fukui Yoshinori、Endo Shogo、Sumimoto Hideki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 17402-17402
- DOI
  10.1038/s41598-017-17597-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01378, KAKENHI-PROJECT-16K08627, KAKENHI-PROJECT-16K08747, KAKENHI-PROJECT-17K19533, KAKENHI-PUBLICLY-17H05804, KAKENHI-PLANNED-26110003, KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-17H04371, KAKENHI-PROJECT-15J03454, KAKENHI-PROJECT-16K15681, KAKENHI-PROJECT-16K15792, KAKENHI-PROJECT-17K08994
[Journal Article] Data on the optimization of behavioral tasks for senescence-accelerated mouse prone 8 (SAMP8)2017
- Author(s)
  S. Yanai and S. Endo
- Journal Title
  
  Data in Brief
  
  Volume: 8 Pages: 262-266
- DOI
  10.1016/j.dib.2016.05.044
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Long-term cilostazol administration ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8) through a dual effect on cAMP and blood-brain barrier.2017
- Author(s)
  Yanai S, Toyohara J, Ishiwata K, Ito H, Endo S.
- Journal Title
  
  Neuropharmacology
  
  Volume: 116 Pages: 246-259
- DOI
  10.1016/j.neuropharm.2016.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-15H03103
[Journal Article] cAMP系増強薬と認知症の治療－既存薬再開発の応用－2017
- Author(s)
  柳井修一、遠藤昌吾
- Journal Title
  
  Geriatric Medicine
  
  Volume: 5 Pages: 23-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Early onset of behavioral alterations in senescence-accelerated mouse prone 8 (SAMP8).2016
- Author(s)
  Yanai S, Endo S.
- Journal Title
  
  Behavioural Brain Research
  
  Volume: in press Pages: 187-195
- DOI
  10.1016/j.bbr.2016.04.026
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24730642, KAKENHI-PROJECT-15H03103
[Journal Article] Preclinical and the first-in-man studies on [11C]CB184 for imaging 18 kDa translocator protein by positron emission tomography2016
- Author(s)
  J.Toyohara, M. Sakata, K. Hatano, S. Yanai, S. Endo, K. Ishibashi, K. Wagatsuma, K. Ishii and K. Ishiwata
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 30 Issue: 8 Pages: 534-543
- DOI
  10.1007/s12149-016-1094-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-25293271
[Journal Article] Suppression of ERK phosphorylation through oxidative stress is involved in the mechanism underlying sevoflurane-induced toxicity in the developing brain2016
- Author(s)
  Yufune S, Satoh Y, Akai R, Ｙoshinaga Y, Kobayashi Y., Endo S, Kazama T.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 21859-21859
- DOI
  10.1038/srep21859
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04970, KAKENHI-PROJECT-25293331, KAKENHI-PROJECT-15H03103
[Journal Article] Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.2016
- Author(s)
  Tanahashi, H.;Tian, Q.B.; Hara, Y.;Sakagami, H.;Endo, S.;Suzuki, T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 20241-20241
- DOI
  10.1038/srep20241
- NAID
  120007100143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26115532, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-26430014
[Journal Article] 巨大地震が飼育動物へ及ぼす影響2015
- Author(s)
  柳井修一、遠藤昌吾
- Journal Title
  
  LABIO21
  
  Volume: 59 Pages: 20-24
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Impaired Th2 differentiation of CD4+ T cells from Rap2b knockout mice.2015
- Author(s)
  Y. Uechi, G. Matsuzaki, M. Suzuki, T. Asato, K. Takei, M. Umikawa, M. Oshiro, I. Maruyama, S. Endo and K Kariya
- Journal Title
  
  Ryukyu Med. J
  
  Volume: 34 Pages: 45-52
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26115532
[Journal Article] Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice.2015
- Author(s)
  S. Yufune, Y. Satoh, I. Takamatsu, H. Ohta, Y. Kobayashi, Y. Takaenoki, G. Pages, J. Pouyssgur, S. Endo, and T. Kazama.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Pages: 102521-102521
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Impaired Th2 differentiation of CD4+ T cells from Rap2b knockout mice.2015
- Author(s)
  Y. Uechi, G. Matsuzaki, M. Suzuki, T. Asato, Kimiko Takei, M. Umikawa, M. Oshiro, I. N. Maruyama, S. Endo and K.-I. Kariya
- Journal Title
  
  Ryukyu Med. J.
  
  Volume: 34 Pages: 45-52
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice2015
- Author(s)
  Yufune S., Satoh Y., Takamatsu I., Ohta H., Kobayashi Y., Takaenoki Y., Pagès G, Pouysségur J, Endo S, and Kazama T.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 10252-10252
- DOI
  10.1038/srep10252
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04970, KAKENHI-PROJECT-25293331, KAKENHI-PUBLICLY-26115532
[Journal Article] Knowledge of Signal Transduction Provides an Approach to Attacking Memory Decline.2015
- Author(s)
  S. Yanai and S. Endo
- Journal Title
  
  Aging Mechanisms; Longevity, Metabolism, and Brain Aging (N. Mori, and I. Mook-Jung, Inhee eds),
  
  Volume: 1 Pages: 257-274
- Data Source
  KAKENHI-PUBLICLY-26115532
[Journal Article] 巨大地震が飼育動物へ及ぼす影響2015
- Author(s)
  柳井修一、遠藤昌吾
- Journal Title
  
  LABIO21
  
  Volume: 59 Pages: 20-24
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26115532
[Journal Article] Knowledge of Signal Transduction Provides an Approach to Attacking Memory Decline.2015
- Author(s)
  S. Yanai and S. Endo
- Journal Title
  
  Aging Mechanisms; Longevity, Metabolism, and Brain Aging (N. Mori, and I. Mook-Jung, Inhee eds)
  
  Volume: 1 Pages: 257-274
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03103
[Journal Article] ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss2015
- Author(s)
  Kurioka T, Matsunobu T, Satoh Y, Niwa K, Endo S, Fujioka M, Shiotani A.
- Journal Title
  
  Scientific Reports
  
  Volume: 18;5 Issue: 1 Pages: 16839-16839
- DOI
  10.1038/srep16839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15624, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-15H04970, KAKENHI-PROJECT-15H04991, KAKENHI-PUBLICLY-26115532
[Journal Article] Targeted deletion of ERK2 in cardiomyocytes attenuates hypertrophic response but provokes pathological stress induced cardiac dysfunction.2014
- Author(s)
  Ulm S, Liu W, Zi M, Tsui H, Chowdhury SK, Endo S, Satoh Y, Prehar S, Wang R, Cartwright EJ, Wang X.
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 72C Pages: 104-116
- DOI
  10.1016/j.yjmcc.2014.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293331, KAKENHI-PROJECT-25560382, KAKENHI-PUBLICLY-26115532
[Journal Article] The effect of diazepam on mouse PTSD-like behaviors induced by the 2011 Tohoku earthquake2014
- Author(s)
  S. Yanai, Y. Semba, and S. Endo.
- Journal Title
  
  Behav Sci Res
  
  Volume: 53 Pages: 27-36
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26115532
[Journal Article] Cilostazol improves hippocampus-dependent long-term memory in mice2014
- Author(s)
  Shuichi Yanai, Yuki Semba, Hideki Ito, & Shogo Endo
- Journal Title
  
  Psychopharmacology
  
  Volume: - Issue: 13 Pages: 2681-2693
- DOI
  10.1007/s00213-014-3442-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24730642, KAKENHI-PROJECT-25560382
[Journal Article] Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy.2014
- Author(s)
  P. Srimontri, S. Endo, T. Sakamoto, Y. Nakayama, A. Kurosaka, S. Itohara, Y. Hirabayashi, K Kato.
- Journal Title
  
  J Neurochem.
  
  Volume: 131 Issue: 5 Pages: 675-687
- DOI
  10.1111/jnc.12838
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560382, KAKENHI-PUBLICLY-26115532
[Journal Article] The effect of diazepam on mouse PTSD-like behaviors induced by the 2011 Tohoku earthquake.2014
- Author(s)
  S. Yanai, Y. Semba, and S. Endo.
- Journal Title
  
  Behav Sci Res
  
  Volume: 53 Pages: 27-36
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560382
[Journal Article] Deficits in memory-guided limb movements impair obstacle avoidance locomotion in Alzheimer’s disease mouse model2014
- Author(s)
  Setogawa S, Yamaura H, Arasaki T, Endo S, Yanagihara D
- Journal Title
  
  Scientific Reports
  
  Volume: 4:7200 Issue: 1 Pages: 1-10
- DOI
  10.1038/srep07220
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J09496, KAKENHI-PROJECT-25560295, KAKENHI-PROJECT-25560382, KAKENHI-PUBLICLY-26115532
[Journal Article] MAPKカスケード2013
- Author(s)
  佐藤泰司、遠藤昌吾
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 649-649
- Data Source
  KAKENHI-PROJECT-25560382
[Journal Article] 神経可塑性・記憶におけるMEK1/2-ERK1/2の役割、2013
- Author(s)
  遠藤昌吾
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 688-691
- Data Source
  KAKENHI-PROJECT-25560382
[Journal Article] MAPKカスケード2013
- Author(s)
  佐藤泰司遠藤昌吾
- Journal Title
  
  Clinical Neuroscience「神経系のMAPキナーゼ」
  
  Volume: Vol 31 Pages: 649-649
- URL
  https://www.chugaiigaku.jp/modules/shop/index.php?main_page=product_info&products_id=1357&PHPSESSID=45c0649080e6cbc570e285dc7e914f81
- Data Source
  KAKENHI-PROJECT-22500304
[Journal Article] Deep cerebellar nuclei play an important role in two-tone discrimination on delay eyeblink conditioning in C57BL/6 mice.2013
- Author(s)
  Sakamoto, T., and Endo, S.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 3 Pages: e59880-e59880
- DOI
  10.1371/journal.pone.0059880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240057, KAKENHI-PROJECT-25293331, KAKENHI-PROJECT-25560382
[Journal Article] Hepatic extracellular signal-regulated kinase 2 suppresses endoplasmic reticulum stress and protects from oxidative stress and endothelial dysfunction2013
- Author(s)
  Kujiraoka T, Satoh Y, Ayaori M, Shiraishi Y, Arai-Nakaya Y, Hakuno D, Yada H, Kuwada N, Endo S, Isoda K, Adachi T.
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 2 Issue: 4
- DOI
  10.1161/jaha.113.000361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293331, KAKENHI-PROJECT-25560382
[Journal Article] Mechanical allodynia but not thermal hyperalgesia is impaired in mice deficient for ERK2 in the central nervous system2012
- Author(s)
  Otsubo Y., Satoh Y., Kodama M., Araki Y., Satomoto M., Sakamoto E., Pages G., Pouyssegur J., Endo S., Kazama T.
- Journal Title
  
  PAIN
  
  Volume: 153 Issue: 11 Pages: 2241-2252
- DOI
  10.1016/j.pain.2012.07.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500304, KAKENHI-PROJECT-23593009
[Journal Article] ERK2 contributes to the control of social behaviors in mice2011
- Author(s)
  Satoh Y., Endo S., Nakata T., Kobayashi Y., Yamada K., Ikeda T., Takeuchi A., Hiramoto T., Watanabe Y., Kazama T
- Journal Title
  
  J. Neuroscience
  
  Volume: 31(33) Issue: 33 Pages: 11953-67
- DOI
  10.1523/jneurosci.2349-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500304
[Journal Article] シナプスにおけるERKシグナリングの役割2010
- Author(s)
  佐藤泰司、遠藤昌吾
- Journal Title
  
  生体の科学
  
  Volume: Vol 61 Pages: 460-461
- Data Source
  KAKENHI-PROJECT-22500304
[Journal Article] 神経系におけるMEK1/2の機能2010
- Author(s)
  佐藤泰司、遠藤昌吾
- Journal Title
  
  生体の科学
  
  Volume: Vol 61 Pages: 462-463
- Data Source
  KAKENHI-PROJECT-22500304
[Journal Article] Protein phosphatase 2A inhibition induces cerebellar long-term depression and declustering of synaptic AMPA receptor.2004
- Author(s)
  Launey T., Endo S., Sakai R., Harano J., Ito M.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 101
  
  Pages: 676-681
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] ERKs regulate PKC-dependent synaptic depression and declustering of glutamate receptors in cerebellar Purkinje cells.2003
- Author(s)
  Endo S., Launey T.
- Journal Title
  
  Neuropharmacology 45
  
  Pages: 863-872
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] Nitric oxide activates extracellular signal-regulated kinase 1/2 and enhances declustering of ionotropic glutamate receptor subunit 2/3 in rat cerebellar Purkinje cells.2003
- Author(s)
  Endo S., Launey T.
- Journal Title
  
  Neuroscience Lett. 350
  
  Pages: 37777-37782
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] ERKs regulate PKC-dependent synaptic depression and declustering of glutamate receptors in cerebellar Purkinje cells.2003
- Author(s)
  Endo S., Launey T.
- Journal Title
  
  J.Biol.Chem. 45
  
  Pages: 122-126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] Glial protein S100B modulates long-term neuronal synaptic plasticity.2002
- Author(s)
  Nishiyama H., Knopfel T., Endo S., Itohara S.
- Journal Title
  
  Proc.Natl.Acad.Sci USA. 99
  
  Pages: 4037-4042
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Journal Article] Impairment of conditioned freezing to tone, but not to context, in Fyn-transgenic mice : Relationship to NMDA receptor subunit 2B function.
- Author(s)
  Kojima N., Sakamoto T., Endo S., Niki H.
- Journal Title
  
  Eur.J.Neurosci. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380373
[Patent] 加齢に伴う認知機能の低下予防又は改善用の組成物2020
- Inventor(s)
  遠藤・柳井・飯田・新谷
- Industrial Property Rights Holder
  遠藤・柳井・飯田・新谷
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] 活性酸素による小脳依存的運動学習及び小脳長期抑圧の制御2024
- Author(s)
  柿澤昌、新崎智子、赤池孝章、柳井修一、遠藤昌吾
- Organizer
  NEURO2024
- Data Source
  KAKENHI-PROJECT-23K18456
[Presentation] レセプト及び特定健診データを用いた認知症新規発症因子の検討2023
- Author(s)
  奈良毬那, 杉江正光, 横関智一, 遠藤昌吾, 原田和昌
- Organizer
  第42回認知症学会
- Data Source
  KAKENHI-PROJECT-23K18456
[Presentation] 柿澤　昌、遠藤　昌吾2023
- Author(s)
  柿澤　昌、遠藤　昌吾
- Organizer
  第147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] 活性酸素シグナルの小脳シナプス長期可塑性および可塑性方向性決定機構への関与.2023
- Author(s)
  柿澤昌、遠藤昌吾.
- Organizer
  第147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-23K18456
[Presentation] 老化に伴うマウスの心身機能低下の評価2023
- Author(s)
  柳井修一, 新崎智子, 遠藤昌吾
- Organizer
  TOBIRA第11回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-23K18456
[Presentation] Involvement of 8-nitro-cGMP ? ERK signals in induction of long-term depression in the mouse cerebellum2022
- Author(s)
  柿澤昌、新崎智子、佐藤泰司、遠藤昌吾
- Organizer
  第95回日本薬理学会年会シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Combined administration of donepezil and cilostazol ameliorates spatial memory impairment in APP knock-in mouse model for Alzheimer's disease.2022
- Author(s)
  S Yanai, T Arasaki, T Saito, T Saido & S Endo.
- Organizer
  第45回日本神経科学大会 (Neuro2022)
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] ホスホジエステラーゼ3阻害剤シロスタゾールによる老化マウスの記憶機能低下の改善と予防2022
- Author(s)
  柳井修一・新崎智子,遠藤昌吾
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of 8-nito-cGMP - ERK signals in the induction of long-term depression in the mouse cerebellum.2022
- Author(s)
  S Kakizawa, T Arasaki, Yasushi Satoh, S Endo.
- Organizer
  2022
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of 8-nitro-cGMP ? ERK signals in induction of long-term depression in the mouse cerebellum2022
- Author(s)
  柿澤昌、新崎智子、佐藤泰司、遠藤昌吾
- Organizer
  第95回日本薬理学会年会シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] Assessment of physical and cognitive frailty in aging mouse model. 22nd World Congress of Gerontology and Geriatrics2022
- Author(s)
  S Yanai, T Arasaki & S Endo
- Organizer
  22nd World Congress of Gerontology and Geriatrics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Combined administration of donepezil and cilostazol ameliorates spatial memory impairment in APP knock-in mouse model for Alzheimer's disease.2022
- Author(s)
  S Yanai, T Arasaki, T Saito, T Saido & S Endo.
- Organizer
  第45回日本神経科学大会 (Neuro2022)
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] 24か月齢アルツハイマー病モデルマウスにおける行動と記憶の性差に関する基礎研究2022
- Author(s)
  張碩文,柳井修一,吉原利典,斉藤貴志,西道隆臣,遠藤昌吾,後藤佐多良,内藤久士．
- Organizer
  第77回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] 24か月齢アルツハイマー病モデルマウスにおける行動と記憶の性差に関する基礎研究．2022
- Author(s)
  張碩文,柳井修一,吉原利典,斉藤貴志,西道隆臣,遠藤昌吾,後藤佐多良,内藤久士
- Organizer
  第77回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] ホスホジエステラーゼ3阻害剤シロスタゾールによる老化マウスの記憶機能低下の改善と予防．2022
- Author(s)
  柳井修一・新崎智子,遠藤昌吾．
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] Tocotrienols attenuate diet-induced obesity development.2022
- Author(s)
  Y Kato, S Yanai, S Endo, K Fukui
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Assessment of physical and cognitive frailty in aging mouse model.2022
- Author(s)
  S Yanai, T Arasaki & S Endo.
- Organizer
  22nd World Congress of Gerontology and Geriatrics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] シロスタゾールとドネペジルの低用量併用による老齢マウスの記憶機能改善．2021
- Author(s)
  柳井修一, 新崎智子, 遠藤昌吾
- Organizer
  日本心理学会第85回大会
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] Comparison of age-related multi-domain phenotype in human and mouse using comprehensive behavioral test battery.2021
- Author(s)
  S Yanai, T Arasaki & S Endo
- Organizer
  第44回日本神経科学大会 / CJK第1回国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Comparison of age-related multi-domain phenotype in human and mouse using comprehensive behavioral test battery.2021
- Author(s)
  S Yanai, T Arasaki & S Endo.
- Organizer
  第44回日本神経科学大会 / CJK第1回国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19752
[Presentation] シロスタゾールとドネペジルの低用量併用による老齢マウスの記憶機能改善2021
- Author(s)
  柳井修一, 新崎智子, 遠藤昌吾
- Organizer
  日本心理学会第85回大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] PDE3阻害剤シロスタゾール：抗血小板薬から認知症治療薬へのドラッグ・リポジショニング2020
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  日本心理学会第84回大会，2020.9.8-11.2，Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] MAP kinase：ERK1／2遺伝子改変マウスを用いた小脳依存性記憶の解析2020
- Author(s)
  吉田彩乃、宮本武典、新崎智子、遠藤昌吾
- Organizer
  第72回日本動物学会・関東支部大会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] MAP kinase：ERK1／2遺伝子改変マウスを用いた小脳依存性記憶の解2020
- Author(s)
  吉田彩乃、宮本武典、新崎智子、遠藤昌吾
- Organizer
  第72回日本動物学会・関東支部大会,　Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Inhibitory effect of tocotrienols on weight gain in different mouse models.2020
- Author(s)
  Y. Kato, S. Endo, S. Yanai, K. Fukui.
- Organizer
  第43回日本基礎老化学会大会，誌上開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] MAP kinase：ERK1／2遺伝子改変マウスを用いた小脳依存性記憶の解析2020
- Author(s)
  吉田彩乃、宮本武典、新崎智子、遠藤昌吾
- Organizer
  第72回日本動物学会・関東支部大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of reactive oxygen species (ROS) - 8-nitro-cGMP signals in cerebellar long-term depression.2020
- Author(s)
  Kakizawa S., Endo S
- Organizer
  The 12th Forum of European Neuroscience, Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] 18F-標識ネオペンチルスチリルピリジンアミロイド-β PETプローブの生物学的評価．2020
- Author(s)
  多胡哲郎・豊原潤・ソウエイソウ・龍田真帆・新崎智子・柳井修一・遠藤昌吾・斉藤貴志・西道隆臣・田中浩士
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Ca2+とレドックスシグナルによる小脳シナプス可塑性の極性決定.2020
- Author(s)
  柿澤昌, 遠藤昌吾.
- Organizer
  生理学研究所研究会「細胞システム理解のためのシグナル応答原理解明の最前線」, Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Amelioration of age-related spatial memory impairment by concurrent administration of sub-effective doses of donepezil and cilostazol.2020
- Author(s)
  S. Yanai, T. Arasaki, S. Endo
- Organizer
  第43回日本基礎老化学会大会，誌上開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] The role of extracellular signal-regulated kinase (ERK) 5 in spinal cord on pathological pain in mice2020
- Author(s)
  Fumihiro Matsuura , Yasushi Satoh, Masanori Kawaguchi, Xin Wang, Shogo Endo,　Takehiko Ikeda
- Organizer
  Euroanaesthesia 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08878
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, ameliorates spatial memory in APP knock-in mouse model of Alzheimer’s disease.2020
- Author(s)
  S. Yanai, T. Arasaki, T. Saito, T. Saido, & S. Endo
- Organizer
  第43回日本神経科学大会, Web開催
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] 細胞外シグナル伝達キナーゼ(ERK)5が疼痛シグナル伝達経路に及ぼす影響2019
- Author(s)
  結城充正　渡邊智美　松浦史博　遠藤昌吾　佐藤泰司　池田健彦
- Organizer
  第66回日本麻酔科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08878
[Presentation] 細胞外シグナル制御キナーゼ(ERK)5の疼痛シグナル制御における役割2019
- Author(s)
  松浦史博, 板倉紗也子, 川口慎憲, 遠藤昌吾, 佐藤泰司, 石塚俊晶, 池田健彦
- Organizer
  第53回日本ペインクリニック学会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Concurrent administration of sub-effective doses of donepezil and phosphodiesterase 3 inhibitor cilostazol restores memory impairment in aged mice.2019
- Author(s)
  Shuichi YANAI, Tomoko Arasaki, Shogo Endo
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, improves blood-brain barrier integrity and ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8).2019
- Author(s)
  S.Yanai, T.Arasaki & S.Endo
- Organizer
  「次世代脳」プロジェクト冬のシンポジウム
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, improves blood-brain barrier integrity and ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8).2019
- Author(s)
  S.Yanai, T.Arasaki & S.Endo
- Organizer
  「次世代脳」プロジェクト冬のシンポジウム
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] レドックスシグナルによる小脳機能制御2019
- Author(s)
  柿澤昌, 遠藤昌吾
- Organizer
  生理学研究所研究会「シグナル動態の可視化と操作に基づく多階層機能解析の新展開」
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Amelioration of potentially harmful oxidative and nitrosative protein modifications by regular exercise in aged animals: A molecular mechanism of the beneficial effects2019
- Author(s)
  Sataro Goto, Shuo-wen Chang, Shohei Shinozaki, Shuichi Yanai, Hideko Nakamoto, Ayako Matsumoto, Hisashi Naito, Hiroyuki Kobayshi, Masao Kaneki, Shogo Endo, & Zsolt Radak
- Organizer
  11th International Association of Gerontology and Geriatrics Asia/Oceania Regional Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] PDE3阻害剤シロスタゾールによる血液脳関門・記憶機能の改善2019
- Author(s)
  柳井修一、新崎智子、遠藤昌吾
- Organizer
  第8回　TOBIRA研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of ROS - 8-nitro-cGMP signals in cerebellar long-term depression.2019
- Author(s)
  Sho Kakizawa, Shogo Endo
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] Involvement of ROS - 8-nitro-cGMP signals in cerebellar long-term depression.2019
- Author(s)
  Sho Kakizawa, Shogo Endo
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Amelioration of potentially harmful oxidative and nitrosative protein modifications by regular exercise in aged animals: A molecular mechanism of the beneficial effects2019
- Author(s)
  Sataro Goto, Shuo-wen Chang, Shohei Shinozaki, Shuichi Yanai, Hideko Nakamoto, Ayako Matsumoto, Hisashi Naito, Hiroyuki Kobayshi, Masao Kaneki, Shogo Endo, & Zsolt Radak
- Organizer
  11th International Association of Gerontology and Geriatrics Asia/Oceania Regional Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] 有酸素トレーニングが老齢マウス脳内のインスリン分解酵素のS-ニトロソ化に及ぼす影響2019
- Author(s)
  張碩文・篠崎昇平・柳井修一・松本綾子・中本英子・小林裕幸・金木正夫・遠藤昌吾・後藤佐多良・内藤久士
- Organizer
  第74回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] レドックスシグナルによる小脳機能制御2019
- Author(s)
  柿澤昌, 遠藤昌吾
- Organizer
  生理学研究所研究会「シグナル動態の可視化と操作に基づく多階層機能解析の新展開」
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] 有酸素トレーニングが老齢マウス脳内のインスリン分解酵素のS-ニトロソ化に及ぼす影響2019
- Author(s)
  張碩文・篠崎昇平・柳井修一・松本綾子・中本英子・小林裕幸・金木正夫・遠藤昌吾・後藤佐多良・内藤久士
- Organizer
  第74回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] 細胞外シグナル制御キナーゼ(ERK)5の疼痛シグナル制御における役割2019
- Author(s)
  松浦史博, 板倉紗也子, 川口慎憲, 遠藤昌吾, 佐藤泰司, 石塚俊晶, 池田健彦
- Organizer
  第53回日本ペインクリニック学会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] PDE3阻害剤シロスタゾールによる血液脳関門・記憶機能の改善2019
- Author(s)
  柳井修一、新崎智子、遠藤昌吾
- Organizer
  第8回　TOBIRA研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-19K22834
[Presentation] Concurrent administration of sub-effective doses of donepezil and phosphodiesterase 3 inhibitor cilostazol restores memory impairment in aged mice.2019
- Author(s)
  Shuichi YANAI, Tomoko Arasaki, Shogo Endo
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H04044
[Presentation] 細胞外シグナル制御キナーゼ(ERK) 5の疼痛シグナル制御における役割2019
- Author(s)
  松浦史博　板倉紗也子　川口慎憲　遠藤昌吾　佐藤泰司　池田健彦
- Organizer
  第8回北関東・甲信越ペインクリニック学会
- Data Source
  KAKENHI-PROJECT-18K08878
[Presentation] 活性酸素シグナルによる小脳シナプス機能制御2018
- Author(s)
  柿澤昌、遠藤昌吾
- Organizer
  生理研研究会「シグナル動態の可視化と操作に基づく多階層機能解析の新展開」
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Involvement of ROS/8-nitro-cGMP signals in cerebellar synaptic plasticity in mice.2018
- Author(s)
  S.Kakizawa, S.Endo.
- Organizer
  World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, maintains and improves memory functions in aged mice.2018
- Author(s)
  S.Yanai, T.Arasaki & S.Endo
- Organizer
  Society for Neuroscience Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] The phosphodiesterase 3 inhibitor cilostazol restores memory impairment and enhances cerebral glucose metabolism in aged mice.2018
- Author(s)
  S.Yanai, T.Tago, J.Toyohara, T.Arasaki & S.Endo
- Organizer
  日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Recovery from spatial memory deficits and increase of cerebral glucose uptake in cilostazol-administered aged mice.2018
- Author(s)
  S.Yanai, T.Tago, J.Toyohara, T.Arasaki & S.Endo.
- Organizer
  第41回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, improves blood-brain barrier integrity and ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8).2017
- Author(s)
  S.Yanai, J.Toyohara, K.Ishiwata, T.Arasaki S.Endo.
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Cilostazol administration ameliorates the impaired conditioned fear in senescence-accelerated mouse prone 8 (SAMP8).2017
- Author(s)
  S.Yanai, T.Arasaki, S.Endo.
- Organizer
  第40回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] cAMP系増強薬と記憶障害の治療―既存薬再開発の応用―2017
- Author(s)
  遠藤昌吾
- Organizer
  OYC　バイオシンポジウム　「老化と加齢性疾患」
- Invited
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] シロスタゾール投与マウスを用いたPRECISEによる行動解析.2017
- Author(s)
  柳井修一、新崎智子、遠藤昌吾
- Organizer
  TOBIRA第6回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] The effect of 8-nitro-cGMP on SNARE complex assembly and memory2017
- Author(s)
  Y.Kishimoto, S.Yanai, S.Endo, T.Akaike, H.Ihara.
- Organizer
  第60回日本神経化学大会
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Preclinical and first-in-man studies of imidazopyridineacetamide, [11C]CB184, as a novel 18 kDa translocator protein seeker.2016
- Author(s)
  Jun Toyohara, Muneyuki Sakata, Kenji Ishibashi, Kei Wagatsuma, Kentaro Hatano, Shuichi Yanai, Shogo Endo, Kenji Ishii and Kiichi Ishiwata.
- Organizer
  Society of nuclear medicine and molecular imaging 2016 annual meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2016-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Up-regulation of NSP3 by oligomeric Abeta; accelerates neuronal death through Cas-independent Rap1A activation.2016
- Author(s)
  五味不二也・遠藤昌吾・内田洋子
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 老化に伴う認知機能低下に対するシロスタゾールとドネペジルの併用効果2016
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  第39回日本基礎老化学会大会
- Place of Presentation
  伊勢原市民文化会館（神奈川県伊勢原市）
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 8-nitro-cGMP on hippocampus-dependent long-term memory in mice.2016
- Author(s)
  Yusuke Kishimoto, Suhichi Yanai, Shogo Endo, Takaaki Akaike, & Hideshi Ihara.
- Organizer
  The 9th International Conference on the Bilogy, Chemisty, and Therapeutic Application of Nitric Oxide
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 老化促進モデルマウスSAMP8における記憶、学習機能の評価2016
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  第31回SAM研究発表会
- Place of Presentation
  京都大学芝蘭会館（京都府京都市）
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 8-ニトロ-cGMPによるホスホジエステラーゼの阻害効果2016
- Author(s)
  遠藤昌吾、新崎智子、藤井重元、赤池孝章
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, as a potential therapeutic target for the treatment of dementia.2016
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo.
- Organizer
  31st International Congress of Psychology
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Long-term administration of cilostazol, a phosphodiesterase 3 inhibitor, enhances memory functions and cerebral glucose metabolism in aged mice2016
- Author(s)
  柳井修一・豊原潤・石渡喜一・新崎智子・遠藤昌吾
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 東日本大震災が引き起こしたマウスの行動変化2015
- Author(s)
  遠藤昌吾
- Organizer
  第９０回実験動物コンファレンス
- Place of Presentation
  日本獣医生命科学大学（東京、武蔵野市）
- Year and Date
  2015-06-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] ATTACKING MEMORY DECLINE THROUGH THE KNOWLEDGE OF SIGNAL TRANSDUCTION PATHWAY2015
- Author(s)
  S. Endo
- Organizer
  IAGG2015
- Place of Presentation
  Chiang Mai Convention and Exhibition Center (Chiang Mai, Thailand)
- Year and Date
  2015-10-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] 東日本大震災が引き起こしたマウスの行動変化2015
- Author(s)
  遠藤昌吾
- Organizer
  第９０回実験動物コンファレン
- Place of Presentation
  日本獣医生命科学大学（東京、武蔵野市）
- Year and Date
  2015-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 行動解析を用いたホスホジエステラーゼ3阻害剤シロスタゾールの記憶改善効果の評価2015
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  首都大学東京バイオコンファレンス2015
- Place of Presentation
  首都大学東京（八王子市、東京）
- Year and Date
  2015-11-06
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] 老化に伴う認知機能低下に対するホスホジエステラーゼ3阻害剤cilostazolの効果2015
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  第38回日本基礎老化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川、横浜）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] MP30/αTTP-ダブルノックアウトマウスを用いたアスコルビン酸およびα-トコフェロール欠乏が及ぼす不安、学習、運動機能への影響2015
- Author(s)
  高橋経太・柳井修一・下門顕太郎・遠藤昌吾・新井洋由・石神昭人
- Organizer
  日本心理学会第79回大会
- Place of Presentation
  名古屋国際会議場（愛知、名古屋）
- Year and Date
  2015-09-22
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 行動解析を用いたホスホジエステラーゼ3阻害剤シロスタゾールの記憶改善効果の評価2015
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  首都大学東京バイオコンファレンス２０１５
- Place of Presentation
  首都大学東京（東京、八王子）
- Year and Date
  2015-11-06
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] ATTACKING MEMORY DECLINE THROUGH THE KNOWLEDGE OF SIGNAL TRANSDUCTION PATHWAY2015
- Author(s)
  S. Endo
- Organizer
  IAGG2015
- Place of Presentation
  Chiang Mai International Convention and Exhibition Center(ChiangMai, Thailand)
- Year and Date
  2015-10-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] 老化に伴う認知機能低下に対するホスホジエステラーゼ3阻害剤cilostazolの効果2015
- Author(s)
  柳井修一・新崎智子・遠藤昌吾
- Organizer
  第38回日本基礎老化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川、横浜）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Long-term administration of cilostazol, a phosphodiesterase 3 inhibitor, prevents memory decline in aged mice models.2015
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際展示場（兵庫、神戸）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H03103
[Presentation] Long-term administration of cilostazol, a phosphodiesterase 3 inhibitor, prevents memory decline in aged mice models.2015
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫、神戸）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] SMP30/αTTP-ダブルノックアウトマウスを用いたアスコルビン酸およびα-トコフェロール欠乏が及ぼす不安、学習、運動機能への影響2015
- Author(s)
  高橋経太・柳井修一・下門顕太郎・遠藤昌吾・新井洋由・石神昭人
- Organizer
  日本心理学会第79回大会
- Place of Presentation
  名古屋国際会議場（愛知、名古屋）
- Year and Date
  2015-09-22
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] 記憶改善薬のスクリーニングとSAM2014
- Author(s)
  遠藤昌吾
- Organizer
  第２９回SAM研究協議会研究発表会
- Place of Presentation
  東京都健康長寿医療センター（板橋区、東京）
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] Phosphodiesterase 3 inhibitor cilostazol improves conditioned fear in SAM-P8 mice.2014
- Author(s)
  S. Yanai, K Kojima, T. Arasaki, and S. Endo.
- Organizer
  Annual meeting of Japan Society for Biomedical Gerontology
- Place of Presentation
  あいち健康プラザ（愛知、大府）
- Year and Date
  2014-07-26
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] Maintenance of memory functions by chronic administration of cilostazol, a phosphodiesterase 3 inhibitor, in aged mice models.2014
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo.
- Organizer
  Neuroscience 2014
- Place of Presentation
  Washignton Convention Center (Washington DC, USA)
- Year and Date
  2014-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] 記憶改善薬のスクリーニングとSAM2014
- Author(s)
  遠藤昌吾
- Organizer
  SAM研究協議会研究発表会
- Place of Presentation
  東京
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Allodynia is reduced in mice deficient for ERK2.2014
- Author(s)
  Y. Satoh, Y. Otsubo, G. Pagès, J. Pouysségur, S. Endo, T. Kazama.
- Organizer
  2014
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] PDE3阻害剤シロスタゾールによる老化促進モデルマウスの記憶障害改善効果2014
- Author(s)
  柳井修一・小島開・新崎智子・遠藤昌吾
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川、横浜）
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PUBLICLY-26115532
[Presentation] Deficits in working memory related to obstacle avoidance during locomotion in Alzheimer’s disease mutant mice.2013
- Author(s)
  S. Setogawa, H. Yamaura, S. Endo, D. Yanagihara.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Distribution of 8-nitro-cGMP and S-guanylated proteins in cerebellum.2013
- Author(s)
  S. Endo, M. Nakamura,T. Arasaki,T. Akaike
- Organizer
  Japan Neuroscience Society
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Annormal pain in mice deficient for ERK2 in the central nervous system.2013
- Author(s)
  Y. Otsubo-iwama, Y. Satoh, S.Endo, G. Pages, J. Pouysegur, T. Yamamoto, Y. Takahashi, T. Kazama
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Deep cerebellar nuclei play an important role in two-tone discrimination on delay eyeblink conditioning in C57BL/6 mice.2013
- Author(s)
  T. Sakamoto, S. Endo.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Deletion of hepatic ERK2 decreased the SERCA2 expressions, which can account for vascular oxidative stress and endothelial dysfunction in metabolic stress.2013
- Author(s)
  T. Adachi, T. Nanba, Y. Satoh, M. Ayaori, Y. Shiraishi, Y.Arai-Nakaya, D. Hakuno, H. Yada, K. Isoda, S. Endo, T. Kujiraoka
- Organizer
  11th International symposium on mechanisms on vasodilation,
- Place of Presentation
  Zurich, Switzerland
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Abnormal neuropathic pain in mice deficient for ERK2 in the central nervous system.2013
- Author(s)
  Otsubo Y., Satoh Y., Kodama M., Araki Y., Satomoto M., Sakamoto E., Pages G., Pouyssegur J., Endo S., Kazama T.
- Organizer
  8th “Pain in Europe” Congress
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Deletion of hepatic ERK2 decreased the SERCA2 expressions, which can account for vascular oxidative stress and endothelial dysfunction in metabolic stress2013
- Author(s)
  Adachi T., Nanba T., Satoh Y., Ayaori M., Shiraishi Y., Arai-Nakaya Y., Endo S., Hakuno D., Yada H., Isoda K.,Endo S., Kujiraoka T
- Organizer
  11th International sumposium on mechanisms of vasolidation (MOVD 2013)
- Place of Presentation
  チューリッヒ、スイス
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Cilostazol, a PDE3 inhibitor, improves learning and memory in mice.2013
- Author(s)
  S. Yanai, Y. Semba, S. Endo.
- Organizer
  Japan Neuroscience Society
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Hepatic ERK2 deficiency develops hepatosteatosis with decreased expression of SERCA2, which can account for metabolic remodeling and endothelial dysfunction2012
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M., Shiraishi Y., Nakaya Y., Endo S., Hakuno D., Isoda K., Adachi T
- Organizer
  米国心臓病学会議2012(AHA 2012)
- Place of Presentation
  ロサンゼルス、米国
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Hepatic ERK suppresses endothelial dysfunction with the alleviation of hepatosteatosis and metabolic remodeling in mice fed high-fat and high-sucrose diet2012
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M., Shiraishi Y., Nakaya Y., Endo S., Hakuno D., Isoda K., Adachi T
- Organizer
  欧州心臓学会議2012(ESC2012)
- Place of Presentation
  ミュンヘン、ドイツ
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Mechanical allodynia but not thermal hyperalgesia is impaired in mice deficient for ERK2 in the central nervous system2012
- Author(s)
  Otsubo Y., Satoh Y., Kodama M., Araki Y., Endo S, Kazama T
- Organizer
  世界疼痛学会2012(IASP 2012)
- Place of Presentation
  ミラノ、イタリア
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Hepatic ERK protects from endothelial dysfunction with the suppression of hepatic steatosis in mice fed high-fat and high-sucrose diet2011
- Author(s)
  Kujiraoka T., Satoh Y., Ayaori M, Hakuno D., Endo S., Niida T., Isoda K., Adachi T
- Organizer
  第84回米国心臓協会学術集会
- Place of Presentation
  オーランド, 米国
- Data Source
  KAKENHI-PROJECT-22500304
[Presentation] Maintenance of memory functions by chronic administration of cilostazol, a phosphodiesterase 3 inhibitor, in aged mice models.
- Author(s)
  Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo
- Organizer
  Annual meeting of Society for Neuroscience
- Place of Presentation
  Washignton D.C., USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Cilostazol,a phosphodiesterase 3 inhibitor, improves memories in senescence accelerated mice.
- Author(s)
  S. Yanai, T. Arasaki, and S. Endo.
- Organizer
  Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25560382
[Presentation] Phosphodiesterase 3 inhibitor cilostazol improves conditioned fear in SAM-P8 mice.
- Author(s)
  S. Yanai, K Kojima, T. Arasaki, and S. Endo.
- Organizer
  Annual meeting of Japan Society for Biomedical Gerontology
- Place of Presentation
  Obu, Aichi, Japan
- Year and Date
  2014-07-26 – 2014-07-27
- Data Source
  KAKENHI-PROJECT-25560382
[]

1. SATOH Yasushi (10505267)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. IKEDA Toshio (80252526)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 柿澤昌 (40291059)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
4. YANAI Shuichi (60469070)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
5. ADACHI Takeshi (50231931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. ARASAKI Tomoko (90645855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
7. 池田健彦 (10262817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. KAZAMA TOMIEI (40158837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Kojima Nobuhiko (80215251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. LAUNEY Thomas (30322704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. Masanori Kawaguchi (60614633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 平井宏和 (70291086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 苅谷研一 (40263371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 海川正人 (00325838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 武居公子 (90325861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 神尾陽子 (00252445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 照井克生 (90256074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 鈴木康之 (60179265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 中田隆博 (40273932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 柳原大 (90252725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 後藤典子 (10251448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 福田敦夫 (50254272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 菱木貴子 (10338022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 高橋哲也 (00589905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TAKISHIMA Kunio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ISHIZUKA Toshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. TOYOHARA Jun

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
29. 野村さやか

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 中野裕康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 佐藤貴浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 坂本敏郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 坂本浩隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 山崎創

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 石渡喜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 荒木幸仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 塩谷彰浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 鈴木匡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 鈴木道雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 阪上洋行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 藤岡正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Endo Shogo 遠藤 昌吾

ENDO Shogo 遠藤 昌吾

遠藤 省吾 エンドウ ショウゴ

遠藤 昌吾 エンドウ ショウゴ

Research Projects

Research Products

Co-Researchers

Aging cerebellum and cognitive declinePrincipal Investigator

Principal Investigator

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Review Section

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Cognitive impairment viewed from the aging cerebellumPrincipal Investigator

Principal Investigator

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Review Section

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Principal Investigator

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Review Section

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Principal Investigator

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Roles of 8-nitro-cGMP pathway as the coincident detector for memory formation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

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Reactive oxygen species; physiological role in the brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Association of cognitive frailty and signal transduction disfunction.Principal Investigator

Principal Investigator

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Principal Investigator

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Motor memory and anti-oxidant agentsPrincipal Investigator

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Principal Investigator

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Principal Investigator

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活性酸素種が担うマウス運動記憶の分散効果Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms underlying spacing effect of memoryPrincipal Investigator

Endo Shogo 遠藤昌吾

ENDO Shogo 遠藤昌吾

遠藤省吾エンドウショウゴ

遠藤昌吾エンドウショウゴ

[Book] Clinical　Neuroscience2013

[Book] Clinical　Neuroscience2013