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Kaisho Tsuneyasu  改正 恒康

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KAISHO Tsuneyasu  改正 恒康

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Researcher Number 60224325
Other IDs
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Affiliation (Current) 2025: 和歌山県立医科大学, その他部局等, 学長特命教授
2025: 大阪大学, 免疫学フロンティア研究センター, 招へい教授
Affiliation (based on the past Project Information) *help 2014 – 2024: 和歌山県立医科大学, 先端医学研究所, 教授
2013 – 2014: 大阪大学, 免疫学フロンティア研究センター, 招へい教授
2013: 大阪大学, 免疫学フロンティア研究センター, 教授
2012 – 2013: 大阪大学, 免疫学フロンティア研究センター・寄附研究部門, 教授
2011 – 2013: 大阪大学, 免疫学フロンティア研究センター, 寄附研究部門教授 … More
2011: 大阪大学, 免疫学フロンティア研究センター, 寄付研究部門教授
2009 – 2010: 理化学研究所, 生体防御研究チーム, チームリーダー
2004 – 2010: 独立行政法人理化学研究所, 生体防御研究チーム, チームリーダー
2007: The Institute of Physical and Chemical Research, 生体防御研究チーム, チームリーダー
2006: RIKEN, Japan, Research Center for Allergy and Immunology, Laboratory for Host Defense, Team Leader., 生体防御チーム, チームリーダー
2006: 独立行政法人理化学研究所, 生体防衛チーム, チームリーダー
2005: 独立行政法人理化学研究所理化学研究所, 生体防御研究チーム, チームリーダー
1999 – 2003: Osaka Univ., Res. Inst. For Microbial Diseases, Associate Professor, 微生物病研究所, 助教授
1999: 兵庫医科大学, 医学部, 助教授
1998: 兵庫医科大学, 先端医学研究所, 講師
1990 – 1993: 大阪大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Immunology / Immunology / Biological Sciences / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 49070:Immunology-related / Transformative Research Areas, Section (III) / Pathology, Infection/Immunology, and related fields / Experimental pathology
Except Principal Investigator
Immunology … More / Transformative Research Areas, Section (III) / アレルギー / Biological Sciences / Biological Sciences Less
Keywords
Principal Investigator
樹状細胞 / Toll様受容体 / I型インターフェロン / 遺伝子欠損マウス / 免疫アジュバント / 樹状細胞サブセット / プロテアソーム / 遺伝子改変マウス / 炎症 / シグナル伝達 … More / 獲得免疫 / 自然免疫 / 自己炎症性疾患 / IκBキナーゼ / Dendritic cell / サブセット / CpG DNA / 免疫不全 / 自己炎症 / 遺伝子変異 / タンパク質分解 / Toll-like receptor / T細胞 / クロスプレゼンテーション / クロスプライミング / 2本鎖RNA / ケモカイン受容体 / MyD88 / 免疫応答 / リポ多糖 / 発がん / マクロファージ / 免疫プロテアソーム / type I interferon / immune adjuvant / LPS / Gene targeting / ケモカイン / 腸管免疫 / XCR1 / がん免疫 / サイトカイン / インターフェロン / B細胞 / NK細胞 / インフラマソーム / 細胞内輸送 / 前駆細胞 / DNAセンサー / 血球分化 / タンパク質輸送 / 炎症性サイトカイン / 抗原提示 / 免疫異常 / double-starnded RNA / plasmacytoid dendritic cell / 形質細胞様樹状細胞 / IκB kinase / gene targeting mice / IκBキナ / Lipopolysaccharides / Adaptive immunity / Innate immunity / アダプター分子 / NK cell / adaptive immunity / innate immunity / gene targeting / follicular dendritic cell / B cell / peripheral lymphoid organ / 末梢リンパ器官 / 遺伝子ターゲッティング / 濾胞樹状細胞 / 末消リンパ器管 / ノックイン / インターフェロン制御因子(IRF) / Etsファミリー / インターフェロン制御因子(IRF) / 転写因子 / ジフテリアトキシン / ウイルス免疫 / 病原体センサー / セリンスレオニンキナーゼ / Toll様受受容体 / インターフェロンα / イミダゾキノリン / 骨髄キメラマウス / アポトーシス / NF-κB / 慢性関筋リウマチ / preB細胞増殖 / 骨髄微小環境 … More
Except Principal Investigator
シグナル伝達 / MyD88 / TLR / 自然免疫 / 多発性骨髄腫 / Delta / Jagged / signal transduction / 感染症 / ノックアウトマウス / 受容体 / インターロイキン6 / インタ-ロイキン6 / インタ-ロイキン / 恒常性維持 / 自己認識 / 自己分子 / 免疫センサー / dopamine / estrogen / Notch ligands / adjuvants / dendritic cells / Th2 cells / TN2細胞 / ドーパミン / エストロゲン / Notchリガンド / アジュバント / 樹状細胞 / Th2細胞 / infection / knockout mice / Innate immunity / receptor / rheumatoid arthritis / autoimmune diseases / Interleukin 6 / ウイルス / 接着因子 / 遺伝子発現 / B細胞初期分化 / 慢性関節リウマチ / 自己免疫疾患 / セルソーター / アウトリーチ活動 / 遺伝子改変マウス / 病原体センサー / 炎症 / Toll様受容体 / サイトカイン / Th1反応 / リポ多糖 / Toll-like receptor / 癌免疫 / JunB / ストロ-マ細胞 / junB / トランスジェニックマウス / 形質細胞腫 Less
  • Research Projects

    (42 results)
  • Research Products

    (750 results)
  • Co-Researchers

    (41 People)
  •  自己炎症性疾患モデルマウスを用いた免疫炎症病態の解明Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Wakayama Medical University
  •  Critical roles of tissue resident macrophagesPrincipal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Wakayama Medical University
  •  Clarification of self recognition mechanisms by intracellular protein fluctuationPrincipal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Wakayama Medical University
  •  Self-referential immune perception

    • Principal Investigator
      山崎 晶
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Osaka University
  •  Underlying mechanisms for immune disorders caused by proteasome dysfunctionsPrincipal Investigator

    • Principal Investigator
      Kaisho Tsuneyasu
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Wakayama Medical University
  •  Molecular mechanisms on antigen presenting cell function and generationPrincipal Investigator

    • Principal Investigator
      Kaisho Tsuneyasu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Wakayama Medical University
  •  ネオ・セルフ生成における免疫プロテアソームの機能的および病理的意義の解明Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Wakayama Medical University
  •  Clarification of novel functions of the protein degradation systemPrincipal Investigator

    • Principal Investigator
      Kaisho Tsuneyasu
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Pathology, Infection/Immunology, and related fields
    • Research Institution
      Wakayama Medical University
  •  ネオ・セルフ生成機構としての免疫プロテアソームの機能的意義Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Wakayama Medical University
  •  Elucidation of the immune regulation by dendritic cell subsetsPrincipal Investigator

    • Principal Investigator
      Kaisho Tsuneyasu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Wakayama Medical University
  •  Clarification of the intestinal immune regulatory mechanisms by dendritic cellsPrincipal Investigator

    • Principal Investigator
      Tsuneyasu Kaisho
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Wakayama Medical University
  •  Clarification of molecular mechanisms for regulating dendritic cell subset functionsPrincipal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Elucidation of behavior and functions of a dendritic cell subset with high crosspresenting activityPrincipal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  抗ウイルス免疫応答における樹状細胞サブセット特異的機能分子の役割Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Homeostatic inflammation: Molecular basis and dysregulation

    • Principal Investigator
      MIYAKE Kensuke
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Mechanisms for dendritic cell responses against host-derived moleculesPrincipal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      2009 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
      The Institute of Physical and Chemical Research
  •  クロスプライミング機能に関与する樹状細胞の機能的動態の解明Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  核酸系免疫アジュバントによる樹状細胞活性化機構とその自己免疫における意義Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Molecular mechanisms for type I interferon production by Toll-like receptor-stimulated dendritic cellsPrincipal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  抗ウイルス免疫応答における樹状細胞サブセット特異的活性化機構の解明Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Dendritic cell activation mechanisms by nucleic by nucleic acid immune adjuvants.Principal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  核酸成分による樹状細胞活性化機構Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  形質細胞様樹状細胞活性化機構とその機能的意義の解明Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Adjuvants that enhance Th2 responses

    • Principal Investigator
      MATSUSHITA Sho
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      アレルギー
    • Research Institution
      Saitama Medical University
  •  樹状細胞活性化におけるIkBキナーゼファミリーの役割Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Identification of novel immune adjuvants and their acting mechanism on dendritic cell functionPrincipal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      RIKEN
  •  樹状細胞亜集団の多様性活性化機構の解明Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  樹状細胞によるTh1/Th2バランスの決定機構Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  小分子アジュバントによる自然免疫活性化を介した抗腫瘍免疫増強効果の解析Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Dendritic cell activation mechanism by Toll-like receptorsPrincipal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  癌細胞の認識とそのシグナル伝達

    • Principal Investigator
      SHIZUO Akira
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  遺伝子欠損マウスによるIκBキナーゼ群の機能の解析Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Toll様受容体刺激による樹状細胞の成熟分化機構の解明Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Mechanism of innate immune response triggered by Toll-like receptors

    • Principal Investigator
      SHIZUO Akira
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  遺伝子欠損マウスを用いてのNK細胞、樹状細胞機能分子の解析Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Mechanism of NK cell dysfunction in C/EBP-γ deficient micePrincipal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Mechanism of B cell proliferation and diffentiation in peripheral lymphoid organsPrincipal Investigator

    • Principal Investigator
      KAISHO Tsuneyasu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Research Institue for Microbial Diseases, Osaka University
  •  ヒトB細胞増殖分化に関与骨髄微小環境の分子機構及びその異常機構の解明Principal Investigator

    • Principal Investigator
      改正 恒康
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  IL-6による発癌機構の解析

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  形質細胞腫/骨髄腫発生機構におけるインタ-ロイキン6とその受容体発現異常の解析

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  ILー6による発癌機構の解析

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  Investigation of the molecular mechanisms of immunological disorders with abnormal expression of the interleukin 6 gene.

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] Autoinflammatory diseases due to defects in degradation or transport of intracellular proteins, in Basic Immunology and Its Clinical Application2023

    • Author(s)
      I. Sasaki, T. Kato, N. Kanazawa, T. Kaisho.
    • Total Pages
      13
    • Publisher
      Springer
    • ISBN
      9789819997800
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Book] Autoinflammatory diseases due to defects in degradation or transport of intracellular proteins, in Basic Immunology and Its Clinical Application2023

    • Author(s)
      I. Sasaki, T. Kato, N. Kanazawa, T. Kaisho.
    • Total Pages
      13
    • Publisher
      Springer
    • ISBN
      9789819997800
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Book] 標準免疫学2013

    • Author(s)
      改正恒康
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Book] Principles of innate immunity, in Sixth Edition Rheumatology vol.12013

    • Author(s)
      T. Kaisho, S. Akira.
    • Publisher
      MOSBY, ELSEVIER
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Book] I型インターフェロン. I nサイトカインのすべて(完全改訂版)2012

    • Author(s)
      改正恒康
    • Publisher
      化学評論社
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Book] I型インターフェロン. In サイトカインのすべて2012

    • Author(s)
      改正恒康
    • Publisher
      化学評論社
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Book] サイトカインのすべて2012

    • Author(s)
      改正恒康
    • Publisher
      化学評論社
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Book] 改正恒康 免疫学 Update- 分子病態の解明と治療への展開2012

    • Author(s)
      邊見弘明, 改正恒康
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Book] 樹状細胞の免疫調節機構. In 免疫学Update 分子病態の解明と治療への展開-2012

    • Author(s)
      邊見弘明、改正恒康
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Book] サイトカインのすべて(完全改訂版)2012

    • Author(s)
      改正恒康
    • Publisher
      化学評論社
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Book] 分子病態の解明と治療への展開2012

    • Author(s)
      改正恒康
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Book] Principles of innate immunity, in Fifth Edition Rheumatology vol.12011

    • Author(s)
      T.Kaisho
    • Publisher
      MOSBY, ELSEVIER
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Book] 免疫の事典2011

    • Author(s)
      改正恒康
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Book] 樹状細胞機能を制御する分子基盤 In アジュバント開発研究の新展開2011

    • Author(s)
      改正恒康
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Book] Rheumatology(Marc C. Hochberg 他編)2011

    • Author(s)
      T. Kaisho and S. Akira
    • Publisher
      ELSEVIER
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Book] アジュバント開発研究の新展開2011

    • Author(s)
      改正恒康
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Book] Principles of innate immunity, in Fifth Edition Rheumatology vol.1(edited by Marc C.Hochberg, Alan J.Silman, Josef S.Smolen, Michael E.Weinblatt. Michael H.Weisman)(1600 John F. Kennedy Boulevard, Suite 1800,Philadelphia,PA19103-2899,USA)2011

    • Author(s)
      T.Kaisho, S.Akira
    • Publisher
      MOSBY, ELSEVIER
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Book] Principles of innate immunity, in Fifth Edition Rheumatology vol.12011

    • Author(s)
      T.Kaisho
    • Publisher
      MOSBY, ELSEVIER
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Book] Principles of innate immunity, in Fifth Edition Rheumatology vol.12011

    • Author(s)
      T.Kaisho
    • Publisher
      MOSBY, ELSEVIER
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Book] Principles of innate immunity, in Fifth Edition Rheumatology vol.12011

    • Author(s)
      T.Kaisho
    • Publisher
      ELSEVIER
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Book] Principles of innate immunity, in Fifth Edition Rheumatology vol.1 (edited by Marc C. Hochberg, Alan J. Silman, Josef S. Smolen, Michael E. Weinblatt. Michael H. Weisman).2011

    • Author(s)
      T. Kaisho and S. Akira.
    • Publisher
      MOSBY, ELSEVIER, USA
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Book] Principles of innate immunity, in Fifth Edition Rheumatology vol.12011

    • Author(s)
      T. Kaisho and S. Akira
    • Total Pages
      11
    • Publisher
      ELSEVIER
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Book] Principles of innate immunity, in Fifth Edition Rheumatology vol.12011

    • Author(s)
      T.Kaisho
    • Publisher
      ELSEVIER
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Book] 総合アレルギー学2010

    • Author(s)
      改正恒康
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Book] 総合アレルギー学2010

    • Author(s)
      改正恒康
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Book] 自然免疫とアレルギーIn総合アレルギー学 改訂2版(福田健編)2010

    • Author(s)
      改正恒康
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Book] 総合アレルギー学2010

    • Author(s)
      改正恒康
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Book] 免疫学最新イラストレイテッド(自然免疫とToll様受容体.In改訂第2版)2009

    • Author(s)
      改正恒康
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Book] RHEUMATOLOGY2008

    • Author(s)
      T.Kaisho
    • Total Pages
      8
    • Publisher
      MOSBY ELSEVIER
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Book] Nucleic Asids in Innate Immunity2008

    • Author(s)
      Tsunevasu. Kaisho
    • Total Pages
      16
    • Publisher
      CEC Press, USA
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Book] Nucleic Acids in Innate Immunity2008

    • Author(s)
      Tsuneyasu Kaisho
    • Total Pages
      16
    • Publisher
      CEC Press, USA
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Book] Nucleic Acids in Innate Immunity2008

    • Author(s)
      Tsuneyasu. Kaisho
    • Total Pages
      16
    • Publisher
      CEC Press, USA
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Book] Characteristics of dendritic cell responses to nucleic acids, in Nucleic Acids in Innate Immunity(edited by Ken J.Ishii and Shizuo Akira)2008

    • Author(s)
      T.Kaisho, T.Sugiyama, K. Hoshino
    • Publisher
      CRC Press, USA
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Book] RHEUMATOLOGY FOURTH EDITION2008

    • Author(s)
      T. Kaisho
    • Publisher
      MOSBY ELSEVIER
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Book] RHEUMATOLOGY2008

    • Author(s)
      T. Kaisho
    • Total Pages
      8
    • Publisher
      MOSBY ELSEVIER
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Journal Article] A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs2024

    • Author(s)
      K. English, R. Kwan, L. E. Holz, C. McGuffog, J.M.M. Krol, D. Kempe, T. Kaisho, W.R. Heath, L. Lisowski, M. Biro, G.W. McCaughan, D.G. Bowen, P. Bertolino.
    • Journal Title

      Nature Communications

      Volume: 15 Issue: 1 Pages: 1261-1261

    • DOI

      10.1038/s41467-024-45612-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18222, KAKENHI-PLANNED-22H05187
  • [Journal Article] TLR9-independent CD8+ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling2024

    • Author(s)
      SRP. Kumar, M. Biswas, D. Cao, S. Arisa, MM. Melero, AK. Lam, AR. Pineros, R. Kapur, T. Kaisho, RJ. Kaufman, W. Xiao, DM. Shayakhmetov, C. Terhorst, YP. de Jong, RW. Herzog.
    • Journal Title

      Molecular Therapy

      Volume: 32 Issue: 2 Pages: 325-339

    • DOI

      10.1016/j.ymthe.2023.11.029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18222, KAKENHI-PLANNED-22H05187
  • [Journal Article] A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages2024

    • Author(s)
      I. Sasaki, Y. Fukuda-Ohta, C. Nakai, N. Wakaki-Nishiyama, C. Okamoto, D. Okuzaki, S. Morita, S. Kaji, Y. Furuta, H. Hemmi, T. Kato, A. Yamamoto, E. Tosuji, SI Saitoh, T. Tanaka, K. Hoshino, S. Fukuda, K. Miyake, E. Kuroda, KJ Ishii, T. Iwawaki, K. Furukawa, T. Kaisho.
    • Journal Title

      Cell Reports

      Volume: 43 Issue: 4 Pages: 113981-113981

    • DOI

      10.1016/j.celrep.2024.113981

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18222, KAKENHI-PROJECT-23K19487, KAKENHI-PROJECT-22K07006, KAKENHI-PROJECT-22K19424, KAKENHI-PLANNED-22H05184, KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-21H04800, KAKENHI-PROJECT-23K27421
  • [Journal Article] Mouse model of autoinflammatory disease with dysfunction of intracellular DNA sensor system2024

    • Author(s)
      加藤喬、佐々木泉、改正恒康.
    • Journal Title

      JSIAD Journal

      Volume: 3 Issue: 1 Pages: 2-7

    • DOI

      10.34563/jsiadjournal.3.1_2

    • ISSN
      2435-7693
    • Year and Date
      2024-02-02
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K18222, KAKENHI-PROJECT-23K19487, KAKENHI-PLANNED-22H05187
  • [Journal Article] 自己炎症と獲得免疫不全を呈するプロテアソーム機能異常症. Proteasome disorders manifesting autoinflammation and adaptive immunodeficiency.2023

    • Author(s)
      改正恒康、金澤伸雄、邊見弘明.
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 80 Pages: 49-55

    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Journal Article] 免疫不全を伴うプロテアソーム関連自己炎症症候群. Proteasome-associated autoinflammatory syndrome with immunodeficiency.2023

    • Author(s)
      改正恒康
    • Journal Title

      アレルギーの臨床

      Volume: 43 Pages: 30-34

    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Journal Article] 免疫不全を伴うプロテアソーム関連自己炎症症候群. Proteasome-associated autoinflammatory syndrome with immunodeficiency.2023

    • Author(s)
      改正恒康
    • Journal Title

      アレルギーの臨床

      Volume: 43 Pages: 30-34

    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Journal Article] Factor VIII Trafficking to CD4+ T cells Shapes its Immunogenicity and Requires Several Types of Antigen Presenting Cells2023

    • Author(s)
      R. Kaczmarek, A. R. Pineros, P. E. Patterson, T. B. Bertolini, G. Q. Perrin, A. Sherman, J. Born, S. Arisa, M. C. Arvin, M. M. Kamocka, M. M. Martinez, K. W. Dunn, S. M. Quinn, J. J. Morris, A. R. Wilhelm, T. Kaisho, M. M. Melero, M. Biswas, M. H. Kaplan, A. K. Linnemann, L. A. George, R. M. Camire, R. W. Herzog.
    • Journal Title

      Blood Journal

      Volume: 20 Pages: 290-305

    • DOI

      10.1182/blood.2022018937

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18222, KAKENHI-PLANNED-22H05187
  • [Journal Article] SpiB regulates the expression of B-cell-related genes and increases the longevity of memory B cells2023

    • Author(s)
      S. Horiuchi, T. Koike, H. Takebuchi, K. Hoshino, I. Sasaki, Y. Fukuda-Ohta, T. Kaisho, D. Kitamura.
    • Journal Title

      Frontiers in Immunology

      Volume: 14 Pages: 1250719-1250719

    • DOI

      10.3389/fimmu.2023.1250719

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18222, KAKENHI-PROJECT-22K07006, KAKENHI-PLANNED-22H05187
  • [Journal Article] 免疫不全を伴うプロテアソーム関連自己炎症症候群. Proteasome-associated autoinflammatory syndrome with immunodeficiency.2023

    • Author(s)
      改正恒康
    • Journal Title

      アレルギーの臨床

      Volume: 43 Pages: 30-34

    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Journal Article] Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks2023

    • Author(s)
      M. Ugur, R J. Labios, C. Fenton, K. Knopper, K. Jobin, F. Imdahl, G. Golda, K. Hoh, A. Grafen, T. Kaisho, A. E. Saliba, D. Grun, G. Gasteiger, M. Bajenoff, W. Kastenmuller.
    • Journal Title

      Immunity

      Volume: 56 Issue: 8 Pages: 1778-1793.e10

    • DOI

      10.1016/j.immuni.2023.06.020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18222, KAKENHI-PLANNED-22H05187
  • [Journal Article] XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections.2023

    • Author(s)
      E. Domenjo Vila, V. Casella, R. Iwabuchi, E. Fossum, M. Pedragosa, Q. Castellvi, P. Cebollada Rica, T. Kaisho, K. Terahara, G. Bocharov, J. Argilaguet, A. Meyerhans.
    • Journal Title

      Cell Rep

      Volume: 42 Issue: 2 Pages: 112123-112123

    • DOI

      10.1016/j.celrep.2023.112123

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] 自己炎症と獲得免疫不全を呈するプロテアソーム機能異常症. Proteasome disorders manifesting autoinflammation and adaptive immunodeficiency.2023

    • Author(s)
      改正恒康、金澤伸雄、邊見弘明.
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 80 Pages: 49-55

    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Journal Article] Tmem45b is essential for inflammation- and tissue injury?induced mechanical pain hypersensitivity2022

    • Author(s)
      Tanioku Tadashi、Nishibata Masayuki、Tokinaga Yasuyuki、Konno Kohtaro、Watanabe Masahiko、Hemmi Hiroaki、Fukuda-Ohta Yuri、Kaisho Tsuneyasu、Furue Hidemasa、Kawamata Tomoyuki
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 45 Pages: 119-119

    • DOI

      10.1073/pnas.2121989119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06956, KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-20H04043, KAKENHI-PROJECT-21K19384, KAKENHI-PROJECT-23K24428
  • [Journal Article] Spi-B alleviates food allergy by securing mucosal barrier and immune tolerance in the intestine.2022

    • Author(s)
      N. Ishihara,Y. Nakamura, K. Yakabe, S. Komiyama, Y. Fujimura, T. Kaisho, S. Kimura, K. Hase.
    • Journal Title

      Front Allergy

      Volume: 3 Pages: 996657-996657

    • DOI

      10.3389/falgy.2022.996657

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H00509, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Transcription factor MafB-mediated inhibition of type I interferons in plasmacytoid dendritic cells2022

    • Author(s)
      Hiroyuki Saiga, Masaki Ueno, Takashi Tanaka, Tsuneyasu Kaisho, Katsuaki Hoshino
    • Journal Title

      International Immunology

      Volume: 34 Issue: 3 Pages: 159-172

    • DOI

      10.1093/intimm/dxab103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07482, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-16H06276
  • [Journal Article] Depletion of cDC1 cells upon immunotherapy of established tumors precludes efficacy. Cancer Research Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy2022

    • Author(s)
      A. Teijeira, S. Garasa, C. luri, C. de Andrea, M. Gato, C. Molina, T. Kaisho, A. Cirella, A. Azpilikueta, S. Wculek, J. Egea, I. Olivera, I. Rodriguez, A. Rouzaut, V. Verkhusha, K. Valencia, D. Sancho, P. Berraondo, I. Melero.
    • Journal Title

      Cancer Research

      Volume: 82 Issue: 23 Pages: 4373-4385

    • DOI

      10.1158/0008-5472.can-22-1046

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice2022

    • Author(s)
      Alcantara Mellissa C.、Suzuki Kentaro、Acebedo Alvin R.、Kajioka Daiki、Hirohata Satoshi、Kaisho Tsuneyasu、Hatano Yu、Yamagata Kazuo、Takahashi Satoru、Yamada Gen
    • Journal Title

      iScience

      Volume: 25 Issue: 12 Pages: 105609-105609

    • DOI

      10.1016/j.isci.2022.105609

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06822, KAKENHI-PROJECT-21K19538, KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H00548, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384, KAKENHI-PLANNED-18H05528
  • [Journal Article] A vaccine targeting resistant tumours by dual T cell plus NK cell attack2022

    • Author(s)
      S. Badrinath, MO. Dellacherie, A. Li, S. Zheng, X. Zhang, M. Sobral, JW. Pyrdol, KL. Smith, Y. Lu, S. Haag, H. Ijaz, F. Connor-Stroud, T. Kaisho, G. Dranoff, GC. Yuan, DJ. Mooney, KW. Wucherpfennig.
    • Journal Title

      Nature

      Volume: 606 Issue: 7916 Pages: 992-998

    • DOI

      10.1038/s41586-022-04772-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Preparation and Inflammasome Activation of Murine Bone Marrow-Derived and Resident Peritoneal Macrophages2022

    • Author(s)
      Sasaki I, Kaisho T.
    • Journal Title

      Methods Mol Biol.

      Volume: 2427 Pages: 95-104

    • DOI

      10.1007/978-1-0716-1971-1_9

    • ISBN
      9781071619704, 9781071619711
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07006, KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific CD8+ T cells in pancreatic cancer.2022

    • Author(s)
      A. L. Burrack, Z. C. Schmiechen, M. T. Patterson, E. A. Miller, E. J. Spartz, M. R. Rollins, J. F. Raynor, J. S. Mitchell, T. Kaisho, B. T. Fife, I. M. Stromnes.
    • Journal Title

      JCI Insight

      Volume: 7 Issue: 7 Pages: 151593-151593

    • DOI

      10.1172/jci.insight.151593

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] 免疫不全を伴うプロテアソーム関連自己炎症症候群. Proteasome-associated autoinflammatory syndrome with immunodeficiency.2022

    • Author(s)
      改正恒康
    • Journal Title

      アレルギーの臨床

      Volume: 43 Pages: 30-34

    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Journal Article] The liver contains distinct interconnected networks of CX3CR1+ macrophages, XCR1+ type 1 and CD301a+ type 2 conventional dendritic cells embedded within portal tracts2022

    • Author(s)
      K. English, S. Yang Tan, R. Kwan, L. E Holz, F. Sierro, C. McGuffog, T. Kaisho, W. R Heath, K. Pa MacDonald, G. W McCaughan, D. G Bowen, P. Bertolino.
    • Journal Title

      Immunol Cell Biol

      Volume: 100 Issue: 6 Pages: 394-408

    • DOI

      10.1111/imcb.12559

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells2022

    • Author(s)
      D. A Michelson, K. Hase, T. Kaisho, C. Benoist, D. Mathis.
    • Journal Title

      Cell

      Volume: 185 Issue: 14 Pages: 2542-2558

    • DOI

      10.1016/j.cell.2022.05.018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H00509, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Conventional Type 1 Dendritic Cells in Intestinal Immune Homeostasis.2022

    • Author(s)
      Sasaki I, Kato T, Hemmi H, Fukuda-Ohta Y, Wakaki-Nishiyama N, Yamamoto A, Kaisho T.
    • Journal Title

      Front Immunol.

      Volume: 13 Pages: 857954-857954

    • DOI

      10.3389/fimmu.2022.857954

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07006, KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21J22615, KAKENHI-PROJECT-21K19384
  • [Journal Article] Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches2022

    • Author(s)
      S. Daehling, A. M. Mansilla, K. Knopper, A. Grafen, D. T Utzschneider, M. Ugur, P. G Whitney, A. Bachem, P. Arampatzi, F. Imdahl, T. Kaisho, D. Zehn, F. Klauschen, N. Garbi, A. Kallies, A.-E. Saliba, G. Gasteiger, S. Bedoui, W. Kastenmuller.
    • Journal Title

      Immunity

      Volume: 55 Issue: 4 Pages: 656-670

    • DOI

      10.1016/j.immuni.2022.03.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake2021

    • Author(s)
      de Mingo Pulido Alvaro, et al. 全著者16名中10番目
    • Journal Title

      Immunity

      Volume: S1074-7613 Issue: 6 Pages: 00181-3

    • DOI

      10.1016/j.immuni.2021.04.019

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Radiation inducible MafB gene is required for thymic regeneration2021

    • Author(s)
      Daiki Hashimoto, Jose Gabriel R. Colet, Aki Murashima, Kota Fujimoto, Yuko Ueda, Kentaro Suzuki, Taiju Hyuga, Hiroaki Hemmi, Tsuneyasu Kaisho, Satoru Takahashi, Yousuke Takahama and Gen Yamada1
    • Journal Title

      Scientific Reports

      Volume: - Issue: 1 Pages: 10439-10439

    • DOI

      10.1038/s41598-021-89836-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07229, KAKENHI-PROJECT-17K08495, KAKENHI-PROJECT-18K07071, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K06956, KAKENHI-PROJECT-21K19538, KAKENHI-PROJECT-20K18150
  • [Journal Article] Immunogenic tumor cell death promotes dendritic cell migration and inhibits tumor growth via enhanced T cell immunity2021

    • Author(s)
      Moriya Taiki、Kitagawa Kurumi、Hayakawa Yuuki、Hemmi Hiroaki、Kaisho Tsuneyasu、Ueha Satoshi、Ikebuchi Ryoyo、Yasuda Ippei、Nakanishi Yasutaka、Honda Tetsuya、Matsushima Koji、Kabashima Kenji、Ueda Mizuki、Kusumoto Yutaka、Chtanova Tatyana、Tomura Michio
    • Journal Title

      iScience

      Volume: 24 Issue: 5 Pages: 102424-102424

    • DOI

      10.1016/j.isci.2021.102424

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-18K07071, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384, KAKENHI-PROJECT-18K14598
  • [Journal Article] プロテアソーム機能不全による自己炎症2021

    • Author(s)
      改正恒康
    • Journal Title

      炎症と免疫

      Volume: 29 Pages: 195-200

    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Journal Article] Effect of CpG Depletion of Vector Genome on CD8 + T Cell Responses in AAV Gene Therapy2021

    • Author(s)
      T. B. Bertolini, J. L. Shirley, I. Zolotukhin, X. Li, T. Kaisho, W. Xiao, S. Kumar, R. W. Herzog
    • Journal Title

      Front Immunol

      Volume: 12 Pages: 672449-672449

    • DOI

      10.3389/fimmu.2021.672449

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Journal Article] プロテアソーム機能不全による自己炎症.2021

    • Author(s)
      改正恒康
    • Journal Title

      炎症と免疫

      Volume: 29 Pages: 195-200

    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Journal Article] IFNβ Is a Potent Adjuvant for Cancer Vaccination Strategies.2021

    • Author(s)
      K. M. Audsley, T. Wagner, C. Ta, H. V. Newnes, A. C. Buzzai, S. A. Barnes, B. Wylie, J. Armitage, T. Kaisho, A. Bosco, A. McDonnell, M. Cruickshank, V. S. Fear, B. Foley, J. Waithman
    • Journal Title

      Frontiers Immunol

      Volume: 12 Pages: 735133-735133

    • DOI

      10.3389/fimmu.2021.735133

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Type I interferon mediated induction of somatostatin leads to suppression of ghrelin and appetite thereby promoting viral immunity in mice2021

    • Author(s)
      Stutte Susanne、Ruf Janina、Kugler Ina、Ishikawa-Ankerhold Hellen、Parzefall Andreas、Marconi Peggy、Maeda Takahiro、Kaisho Tsuneyasu、Krug Anne、Popper Bastian、Lauterbach Henning、Colonna Marco、von Andrian Ulrich、Brocker Thomas
    • Journal Title

      Brain, Behavior, and Immunity

      Volume: S0889-1591 Pages: 00176-8

    • DOI

      10.1016/j.bbi.2021.04.018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K19384
  • [Journal Article] Augmentation of STING‐induced type I interferon production in COPA syndrome2021

    • Author(s)
      Kato Takashi、Yamamoto Masaki、Honda Yoshitaka、Orimo Takashi、Sasaki Izumi、Murakami Kohei、Hemmi Hiroaki、Fukuda‐Ohta Yuri、Isono Kyoichi、Takayama Saki、Nakamura Hidenori、Otsuki Yoshiro、Miyamoto Toshiaki、Takita Junko、Yasumi Takahiro、Nishikomori Ryuta、Matsubayashi Tadashi、Izawa Kazushi、Kaisho Tsuneyasu
    • Journal Title

      Arthritis & Rheumatology

      Volume: in press Issue: 11 Pages: 2105-2115

    • DOI

      10.1002/art.41790

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-18K16096, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-19K08299, KAKENHI-PROJECT-20K16289, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21J22615, KAKENHI-PROJECT-21K06956, KAKENHI-PROJECT-21K09216, KAKENHI-PROJECT-21K19384, KAKENHI-PROJECT-21K19405
  • [Journal Article] Effect of CpG Depletion of Vector Genome on CD8 + T Cell Responses in AAV Gene Therapy.2021

    • Author(s)
      Thais B Bertolini, Jamie L Shirley, Irene Zolotukhin, Xin Li, Tsuneyasu Kaisho, Weidong Xiao, Sandeep Kumar, Roland W. Herzog
    • Journal Title

      Front Immunol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Journal Article] 自然免疫が関与する炎症―自然炎症と自己炎症性疾患2020

    • Author(s)
      改正恒康
    • Journal Title

      医学のあゆみ

      Volume: 274 Pages: 379-386

    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Journal Article] PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB2020

    • Author(s)
      Jodo Aya、Shibazaki Azusa、Onuma Asuka、Kaisho Tsuneyasu、Tanaka Takashi
    • Journal Title

      Frontiers in Immunology

      Volume: 11 Pages: 1559-1559

    • DOI

      10.3389/fimmu.2020.01559

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-20H03505
  • [Journal Article] The mechanism of action of Spi-B in the transcriptional activation of the interferon-α4 gene.2020

    • Author(s)
      R. Miyazaki, H. Saiga, T. Kato, T. Bakoshi, R. Senba, A. Shintani, M. Suzuki, K. Takao, I. Sasaki, A. Iizuka, M. Sugiyama, N. Iwami, Y. Fukuda-Ohta, H. Hemmi, T. Tanaka, M. Miyake, T. Kaisho, K. Hoshino.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 30;525 Issue: 2 Pages: 477-482

    • DOI

      10.1016/j.bbrc.2020.02.101

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K16096, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-18K07071
  • [Journal Article] Anticancer effects of chemokine-directed antigen delivery to a cross-presenting dendritic cell subset with immune checkpoint blockade2020

    • Author(s)
      Mizumoto Y, Hemmi H, Katsuda M, Miyazawa M, Kitahata Y, Miyamoto A, Nakamori M, Ojima T, Matsuda K, Nakamura M, Hayata K, Fukuda-Ohta Y, Sugiyama M, Ohta T, Orimo T, Okura S, Sasaki I, Tamada K, Yamaue H, Kaisho T.
    • Journal Title

      British Journal of Cancer

      Volume: 122 Issue: 8 Pages: 1185-1193

    • DOI

      10.1038/s41416-020-0757-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07071, KAKENHI-PROJECT-19K09183, KAKENHI-PROJECT-18K16096, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17K10603, KAKENHI-PROJECT-17K10604, KAKENHI-PROJECT-17K10711, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-20K09063, KAKENHI-PROJECT-19K18101, KAKENHI-PROJECT-20K16289, KAKENHI-PROJECT-17H01580, KAKENHI-PROJECT-19K23848
  • [Journal Article] Osteoprotegerin-dependent Mcell self-regulation balances gut infection and immunity.2020

    • Author(s)
      Kimura S, Nakamura Y, Kobayashi N, Shiroguchi K, KawakamiE, Mutoh M, Takahashi-Iwanaga H, Yamada T, Hisamoto M, Nakamura M, Udagawa N, Sato S, KaishoT, Iwanaga T, Hase K.
    • Journal Title

      Nat Commun

      Volume: 11 Issue: 1 Pages: 234-234

    • DOI

      10.1038/s41467-019-13883-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08504, KAKENHI-PROJECT-19K07239, KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-19K22532, KAKENHI-PROJECT-19K21170, KAKENHI-PUBLICLY-18H04680, KAKENHI-PLANNED-18H05411, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17H04089, KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-17KT0055, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-20K21689
  • [Journal Article] IL-12 From Endogenous cDC1, and Not Vaccine DC, Is Required for Th1 Induction.2020

    • Author(s)
      D. Ashour, P. Arampatzi, V. Pavlovic, K. U Forstner, T. Kaisho, A. Beilhack, F. Erhard, M. B Lutz.
    • Journal Title

      JCI Insight

      Volume: 21;5 Issue: 10 Pages: 135143-135143

    • DOI

      10.1172/jci.insight.135143

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088
  • [Journal Article] Display of Native Antigen on cDC1 That Have Spatial Access to Both T and B Cells Underlies Efficient Humoral Vaccination2020

    • Author(s)
      Kato Yu、Steiner Thiago M.、Park Hae-Young、Hitchcock Rohan O.、Zaid Ali、Hor Jyh Liang、Devi Sapna、Davey Gayle M.、Vremec David、Tullett Kirsteen M.、Tan Peck S.、Ahmet Fatma、Mueller Scott N.、Alonso Sylvie、Tarlinton David M.、Ploegh Hidde L.、Kaisho Tsuneyasu、et al. 全著者24名中17番目
    • Journal Title

      The Journal of Immunology

      Volume: 205 Issue: 7 Pages: 1842-1856

    • DOI

      10.4049/jimmunol.2000549

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-20H03505
  • [Journal Article] Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity2020

    • Author(s)
      Nakamura Yutaka、Mimuro Hitomi、Kunisawa Jun、Furusawa Yukihiro、Takahashi Daisuke、Fujimura Yumiko、Kaisho Tsuneyasu、Kiyono Hiroshi、Hase Koji
    • Journal Title

      Mucosal Immunology

      Volume: in press Issue: 4 Pages: 679-690

    • DOI

      10.1038/s41385-020-0263-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04680, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17H04089, KAKENHI-PROJECT-17KT0055, KAKENHI-PROJECT-19K21170, KAKENHI-PROJECT-18H05280
  • [Journal Article] Systems analysis reveals complex biological processes during virus infection fate decisions.2019

    • Author(s)
      Argilaguet. J, Pedragosa. M, Esteve-Codina. A, Riera. G, Vidal. E, Peligero-Cruz. C, Casella. V, Andreu. D, Kaisho. T, Bocharov. G, Ludewig. B, Heath. S, Meyerhans. A.
    • Journal Title

      Genome Res

      Volume: 29 Issue: 6 Pages: 907-919

    • DOI

      10.1101/gr.241372.118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088
  • [Journal Article] Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome2019

    • Author(s)
      Orimo T, Sasaki I, Hemmi H, Ozasa T, Fukuda-Ohta Y, Ohta T, Morinaka M, Kitauchi M, Yamaguchi T, Sato Y, Tanaka T, Hoshino K, Katayama KI, Fukuda S, Miyake K, Yamamoto M, Satoh T, Furukawa K, Kuroda E, Ishii KJ, Takeda K, Kaisho T
    • Journal Title

      International Immunology

      Volume: 印刷中 Issue: 10 Pages: 657-668

    • DOI

      10.1093/intimm/dxz004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07071, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-19K22518, KAKENHI-PROJECT-18K16096, KAKENHI-PROJECT-19K23848, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17K19616, KAKENHI-PROJECT-18H02628
  • [Journal Article] Identification of a novel CCDC22 mutation in a patient with severe Epstein?Barr virus-associated hemophagocytic lymphohistiocytosis and aggressive natural killer cell leukemia2019

    • Author(s)
      Yamashita Y, Nishikawa A, Iwahashi Y, Fujimoto M, Sasaki I, Mishima H, Kinoshita A, Hemmi H, Kanazawa N, Ohshima K, Imadome KI, Murata SI、Yoshiura KI, Kaisho T, Sonoki T, Tamura S
    • Journal Title

      International Journal of Hematology

      Volume: 印刷中 Issue: 6 Pages: 744-750

    • DOI

      10.1007/s12185-019-02595-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07071, KAKENHI-PROJECT-18K07850, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-19K08821, KAKENHI-PROJECT-19K22913, KAKENHI-PROJECT-18KK0245, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-16KT0112
  • [Journal Article] Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice2019

    • Author(s)
      Kimura Shunsuke、Kobayashi Nobuhide、Nakamura Yutaka、Kanaya Takashi、Takahashi Daisuke、Fujiki Ryoji、Mutoh Mami、Obata Yuuki、Iwanaga Toshihiko、Nakagawa Tomoo、Kato Naoya、Sato Shintaro、Kaisho Tsuneyasu、Ohno Hiroshi、Hase Koji
    • Journal Title

      The Journal of Experimental Medicine

      Volume: 216 Issue: 4 Pages: 831-846

    • DOI

      10.1084/jem.20181604

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-16H05207, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-16J09413, KAKENHI-PROJECT-16K08457, KAKENHI-PROJECT-16K08836, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-19K22532, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-19H03702
  • [Journal Article] Hyperglycemia is associated with psoriatic inflammation in both humans and mice2019

    • Author(s)
      Ikumi K, Odanaka M, Shime H, Imai M, Osaga S, Taguchi O, Nishida E, Hemmi H, Kaisho T, Morita A, Yamazaki S
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 印刷中 Issue: 6 Pages: 1329-1338

    • DOI

      10.1016/j.jid.2019.01.029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07071, KAKENHI-PUBLICLY-17H05798, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-16H05177, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-16K08704, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-19K07510, KAKENHI-PROJECT-19KK0202, KAKENHI-PUBLICLY-19H04812, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04242, KAKENHI-PROJECT-17K11679
  • [Journal Article] A defined commensal consortium elicits CD8 T cells and anti-cancer immunity2019

    • Author(s)
      T.Tanoue, S.Morita, D.R.Plichta, A.N.Skelly, W.Suda, Y.Sugiura, S.Narushima, H.Vlamakis, I.Motoo, K.Sugita, A.Shiota, K.Takeshita, K.Yasuma, D.Riethmacher, T.Kaisho, J.M.Norman, D.Mucida, M.Suematsu, T.Yaguchi, V.Bucci, T.Inoue, Y.Kawakami, B.Olle, B.Roberts, M.Hattori, R.J.Xavier, K.Atarashi, K.Honda
    • Journal Title

      Nature

      Volume: 565 Issue: 7741 Pages: 600-605

    • DOI

      10.1038/s41586-019-0878-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17J01289, KAKENHI-PROJECT-17K19568, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-16K08091
  • [Journal Article] Programmed cell death ligand 1 disruption by clustered regularly interspaced short palindromic repeats/Cas9‐genome editing promotes antitumor immunity and suppresses ovarian cancer progression2019

    • Author(s)
      Yahata T, Mizoguchi M, Kimura A, Orimo T, Toujima S, Kuninaka Y, Nosaka M, Ishida Y, Sasaki I, Fukuda‐Ohta Y, Hemmi H, Iwahashi N, Noguchi T, Kaisho T, Kondo T, Ino K
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 4 Pages: 1279-1292

    • DOI

      10.1111/cas.13958

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07071, KAKENHI-PROJECT-18K10134, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-18K16096, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17K11293, KAKENHI-PROJECT-17K16863
  • [Journal Article] Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells.2019

    • Author(s)
      Tsuchiya N, Zhang R, Iwama T, Ueda N, Liu T, Tatsumi M, Sasaki Y, Shimoda R, Osako Y, Sawada Y, Kubo Y, Miyashita A, Fukushima S, Cheng Z, Nakaki R, Takubo K, Okada S, Kaneko S, Ihn H, Kaisho T, Nishimura Y, Senju S, Endo I, Nakatsura T, Uemura Y.
    • Journal Title

      Cell Rep.

      Volume: 29 Issue: 1 Pages: 162-175

    • DOI

      10.1016/j.celrep.2019.08.086

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08301, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806, KAKENHI-PROJECT-18K19570, KAKENHI-PROJECT-17K16345, KAKENHI-PROJECT-18H02641, KAKENHI-PLANNED-16H06498
  • [Journal Article] antibiotics enhances host resistance to viral infections in a microbiota-independent manner2018

    • Author(s)
      Smita Gopinath, Myoungjoo Kim, Tasfia Rakib, Patrick Wong, Michael Van Zandt, Natasha Barry, Tsuneyasu Kaisho, Andrew Goodman, Akiko Iwasaki
    • Journal Title

      Nature MicrobiologyTopical application of aminoglycoside

      Volume: 3 Issue: 5 Pages: 611-621

    • DOI

      10.1038/s41564-018-0138-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17K19568
  • [Journal Article] 生体内における樹状細胞への腫瘍抗原送達システムによる新規がんペプチドワクチン療法2018

    • Author(s)
      2.水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、尾島敏康、松田健司、邊見弘明、玉田耕治、改正恒康、山上裕機
    • Journal Title

      癌と化学療法

      Volume: 45 Pages: 1469-1471

    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Journal Article] Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles.2018

    • Author(s)
      Kayama H, Kohyama M, Okuzaki D, Motooka D, Barman S, Okumura R, Muneta M, Hoshino K, Sasaki I, Ise W, Matsuno H, Nishimura J, Kurosaki T, Nakamura S, Arase H, Kaisho T, Takeda K.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 115 Issue: 33 Pages: 8418-8423

    • DOI

      10.1073/pnas.1808426115

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07174, KAKENHI-PROJECT-18K19447, KAKENHI-PUBLICLY-17H05793, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-18H04028, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-15K08531, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-15H02545, KAKENHI-PROJECT-18H05279, KAKENHI-PROJECT-18K19450
  • [Journal Article] 生体内における樹状細胞への腫瘍抗原送達システムによる新規がんペプチドワクチン療法2018

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、尾島敏康、松田健司、邊見弘明、玉田耕治、改正恒康、山上裕機
    • Journal Title

      癌と化学療法

      Volume: 45 Pages: 1469-1471

    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Journal Article] 生体内における樹状細胞への腫瘍抗原送達システムによる新規がんペプチドワクチン療法2018

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、尾島敏康、松田健司、邊見弘明、玉田耕治、改正恒康、山上裕機
    • Journal Title

      癌と化学療法

      Volume: 45 Pages: 1469-1471

    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Journal Article] XCR1+樹状細胞による腸管免疫制御機構2018

    • Author(s)
      小笹俊哉、改正恒康
    • Journal Title

      医学のあゆみ

      Volume: 265(13) Pages: 1241-1247

    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Journal Article] XCR1+樹状細胞による腸管免疫制御機構2018

    • Author(s)
      小笹俊哉、改正恒康
    • Journal Title

      医学のあゆみ

      Volume: 265(13) Pages: 1241-1247

    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Journal Article] XCR1+樹状細胞による腸管免疫制御機構2018

    • Author(s)
      小笹俊哉、改正恒康
    • Journal Title

      医学のあゆみ

      Volume: 265(13) Pages: 1241-1247

    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Journal Article] Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration.2017

    • Author(s)
      4.Y. Ishida, A. Kimura, M. Nosaka, Y. Kuninaka, H. Hemmi, I. Sasaki, T. Kaisho, N. Mukaida, T. Kondo.
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 16833-16833

    • DOI

      10.1038/s41598-017-17007-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-26293163, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-15K08431, KAKENHI-PROJECT-15K08880
  • [Journal Article] 樹状細胞による腸管免疫恒常性維持機構2017

    • Author(s)
      大田友和、改正恒康
    • Journal Title

      実験医学

      Volume: 35 Pages: 1103-1109

    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Journal Article] Ultraviolet B?Induced Maturation of CD11b-Type Langerin?Dendritic Cells Controls the Expansion of Foxp3+Regulatory T Cells in the Skin2017

    • Author(s)
      Yamazaki Sayuri、Odanaka Mizuyu、Nishioka Akiko、Kasuya Saori、Shime Hiroaki、Hemmi Hiroaki、Imai Masaki、Riethmacher Dieter、Kaisho Tsuneyasu、Ohkura Naganari、Sakaguchi Shimon、Morita Akimichi
    • Journal Title

      The Journal of Immunology

      Volume: 200 Issue: 1 Pages: 119-129

    • DOI

      10.4049/jimmunol.1701056

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08704, KAKENHI-PROJECT-17K11679, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-16H06295, KAKENHI-PUBLICLY-17H05798, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-15H04744, KAKENHI-PROJECT-16H05177, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-15K08431, KAKENHI-PROJECT-16K15259, KAKENHI-PROJECT-16K15376, KAKENHI-PROJECT-17H04242
  • [Journal Article] 樹状細胞による腸管免疫恒常性維持機構2017

    • Author(s)
      大田友和、改正恒康
    • Journal Title

      実験医学

      Volume: 35 Pages: 1103-1109

    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Journal Article] 樹状細胞2017

    • Author(s)
      改正恒康
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 67 Pages: 606-611

    • NAID

      40021232347

    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Journal Article] CD8+ T cells orchestrate pDC-XCR1+ dendritic cell spatial and functional cooperativity to optimize priming.2017

    • Author(s)
      A. Brewitz, S. Eickhoff, S. Daehling, T. Quast, S. Bedoui, R. A. Kroczek, C. Kurts, N. Garbi, W. Barchet, M. Iannacone, F. Klauschen, W. Kolanus, T. Kaisho, M. Colonna, R. N. Germain, W. Kastenmueller.
    • Journal Title

      Immunity

      Volume: 46 Issue: 2 Pages: 205-219

    • DOI

      10.1016/j.immuni.2017.01.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19568, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-17H04088
  • [Journal Article] 樹状細胞2017

    • Author(s)
      改正恒康
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 67 Pages: 606-611

    • NAID

      40021232347

    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Journal Article] Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections.2017

    • Author(s)
      Shimokawa C, Kanaya T, Hachisuka M, Ishiwata K, Hisaeda H, Kurashima Y, Kiyono H, Yoshimoto T, Kaisho T, Ohno H.
    • Journal Title

      Immunity

      Volume: 46 Issue: 5 Pages: 863-874

    • DOI

      10.1016/j.immuni.2017.04.017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08441, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-15H05274, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-15H04865, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17K19575, KAKENHI-PROJECT-26870849, KAKENHI-PROJECT-16H06243
  • [Journal Article] 樹状細胞2017

    • Author(s)
      改正恒康
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 67 Pages: 606-611

    • NAID

      40021232347

    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Journal Article] Development of a novel CD4+ TCR transgenic line that reveals a dominant role for CD8+ DC and CD40-Signaling in the generation of helper and CTL responses to blood stage malaria.2017

    • Author(s)
      3.D. Fernandez-Ruiz, LS. Lau, N. Ghazanfari, ..names of 12 authors were removed,,, A. Cozijnsen, V. Mollard, AD. Uboldi, CJ. Tonkin, TF. de Koning-Ward, PR. Gilson, T. Kaisho, A. Haque, BS. Crabb, FR. Carbone, GI. McFadden, WR. Heath.
    • Journal Title

      J. Immunol.

      Volume: 199 Issue: 12 Pages: 4165-4179

    • DOI

      10.4049/jimmunol.1700186

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19568, KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-17H04088
  • [Journal Article] 樹状細胞による腸管免疫恒常性維持機構2017

    • Author(s)
      大田友和、改正恒康
    • Journal Title

      実験医学

      Volume: 35 Pages: 1103-1109

    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Journal Article] Critical role for CD103+/CD141+ dendritic cells bearing CCR7 for tumor antigen trafficking and priming of T cell immunity in melanoma.2016

    • Author(s)
      E. W. Roberts, M. L. Broz, M. Binnewies, M. B. Headley, A. E. Nelson, D. M. Wolf, T. Kaisho, D. Bogunovic, N. Bhardwaj, M. F. Krummel.
    • Journal Title

      Cancer Cell

      Volume: 30 Issue: 2 Pages: 324-336

    • DOI

      10.1016/j.ccell.2016.06.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Journal Article] Antigen-specific cytotoxic T lymphocytes target airway CD103(+) and CD11b(+) dendritic cells to suppress allergic inflammation2016

    • Author(s)
      Daniels N. J., Hyde E., Ghosh S., Seo K., Price K. M., Hoshino K., Kaisho T., Okada T. and Ronchese F.
    • Journal Title

      Mucosal immunology

      Volume: 9 Issue: 1 Pages: 229-239

    • DOI

      10.1038/mi.2015.55

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461465, KAKENHI-PROJECT-26293106
  • [Journal Article] Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney2016

    • Author(s)
      Sato Y, Mii A, Hamazaki Y, Fujita H, Nakata H, Masuda K, Nishiyama S, Shibuya S, Haga H, Ogawa O, Shimizu A, Narumiya S, Kaisho T, Arita M, Yanagisawa M, Miyasaka M, Sharma K, Minato N, Kawamoto H, and Yanagita M.
    • Journal Title

      JCI. Insight.

      Volume: 1 Issue: 11

    • DOI

      10.1172/jci.insight.87680

    • NAID

      120005820865

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01154, KAKENHI-PLANNED-24111008, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-15H04743, KAKENHI-PROJECT-25293069, KAKENHI-PROJECT-26293106, KAKENHI-PROJECT-16K09870, KAKENHI-PROJECT-15K15151
  • [Journal Article] Imaging of the cross-presenting dendritic cell subsets in the skin-draining lymph node2016

    • Author(s)
      Kitano M., Yamazaki C., Takumi A., Ikeno T., Hemmi H., Takahashi N., Shimizu K., Fraser S. E., Hoshino K., Kaisho T. and Okada T.
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 113 Issue: 4 Pages: 1044-1049

    • DOI

      10.1073/pnas.1513607113

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461465, KAKENHI-PROJECT-26293106
  • [Journal Article] Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis.2016

    • Author(s)
      Ohta T, Sugiyama M, Hemmi H, Yamazaki C, Okura S, Sasaki I, Fukuda Y, Orimo T, Ishii KJ, Hoshino K, Ginhoux F, Kaisho T.
    • Journal Title

      Scientific Reports

      Volume: 162 Issue: 1 Pages: 23505-23505

    • DOI

      10.1038/srep23505

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08431, KAKENHI-PROJECT-26461465, KAKENHI-PROJECT-15K19077, KAKENHI-PROJECT-14J04735, KAKENHI-PROJECT-26293106, KAKENHI-PROJECT-16K19585
  • [Journal Article] In vivo ablation of dendritic cell subset expressing the chemokine receptor XCR1.2016

    • Author(s)
      H. Hemmi, K. Hoshino, T. Kaisho.
    • Journal Title

      Methods Mol Biol.

      Volume: 1423 Pages: 247-53

    • DOI

      10.1007/978-1-4939-3606-9_17

    • ISBN
      9781493936045, 9781493936069
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293106, KAKENHI-PROJECT-15K08431, KAKENHI-PROJECT-26461465
  • [Journal Article] 自己免疫疾患における自然免疫システムの役割2015

    • Author(s)
      改正恒康
    • Journal Title

      実験医学(増刊)

      Volume: 33 Pages: 1871-76

    • Data Source
      KAKENHI-PROJECT-26293106
  • [Journal Article] PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm.2015

    • Author(s)
      Ono, R., Kaisho, T., Tanaka, T.
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 18327-18327

    • DOI

      10.1038/srep18327

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08536, KAKENHI-PROJECT-26293106
  • [Journal Article] Robust anti-viral immunity requires multiple distinct t cell-dendritic cell interactions.2015

    • Author(s)
      S. Eickhoff, A. Brewitz, M. Y. Gerner, F. Klauschen, K. Komander, H. Hemmi, N. Garbi, T. Kaisho, R. N. Germain, W. Kastenmüller.
    • Journal Title

      Cell

      Volume: 162 Issue: 6 Pages: 1322-1337

    • DOI

      10.1016/j.cell.2015.08.004

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Journal Article] 樹状細胞サブセットと内因性リガンド2015

    • Author(s)
      大田友和、改正恒康
    • Journal Title

      炎症と免疫

      Volume: 23 Pages: 477-482

    • Data Source
      KAKENHI-PROJECT-26293106
  • [Journal Article] Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells.2015

    • Author(s)
      H. Sasaki, D. Kurotaki, N. Osato, H. Sato, I. Sasaki, S. Koizumi, H. Wang, C. Kaneda, A. Nishiyama, T. Kaisho, H. Aburatani, H. C. Morse III, K. Ozato, T. Tamura.
    • Journal Title

      Blood

      Volume: 125(2) Issue: 2 Pages: 358-369

    • DOI

      10.1182/blood-2014-02-557983

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-24390246, KAKENHI-PROJECT-24790322, KAKENHI-PROJECT-25870401, KAKENHI-PROJECT-26293106, KAKENHI-PROJECT-26460373, KAKENHI-PROJECT-15K19077
  • [Journal Article] Homeostasis of thymus-derived Foxp3+ regulatory T cells is controlled by ultraviolet B exposure in the skin.2014

    • Author(s)
      S. Yamazaki, A. Nishioka, S. Kasuya, N. Ohkura, H. Hemmi, T. Kaisho, O. Taguchi, S. Sakaguchi, A. Morita
    • Journal Title

      J Immunol

      Volume: 193(11) Issue: 11 Pages: 5488-97

    • DOI

      10.4049/jimmunol.1400985

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-24590460, KAKENHI-PROJECT-26293106, KAKENHI-PROJECT-26670192
  • [Journal Article] Olfactory plays a key role in spatiotemporal pathogenesis of cerebral malaria.2014

    • Author(s)
      H. Zhao, T. Aoshi, S. Kawai, Y. Mori, A. Konishi, M. Ozkan, Y. Fujita, Y. Haseda, M. Shimizu, M. Kohyama, K. Kobiyama, K. Eto, J. Nabekura, T. Horii, T. Ishino, M. Yuda, H. Hemmi, T. Kaisho, S. Akira, M. Kinoshita, K. Tohyama, Y. Yoshioka, K. J. Ishii, C. Coban
    • Journal Title

      Cell Host Microbe

      Volume: 15 Issue: 5 Pages: 551-563

    • DOI

      10.1016/j.chom.2014.04.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-24249024, KAKENHI-PROJECT-24249077, KAKENHI-PROJECT-24590460, KAKENHI-PROJECT-24590584, KAKENHI-PROJECT-25253027, KAKENHI-PROJECT-25293100, KAKENHI-PROJECT-26293106, KAKENHI-PROJECT-26860996
  • [Journal Article] HSP70 mediates degradation of the p65 subunit of nuclear factor κB to inhibit inflammatory signaling2014

    • Author(s)
      T. Tanaka, A. Shibazaki, R. Ono, T. Kaisho
    • Journal Title

      Sci. Signal

      Volume: 7(356) Issue: 356

    • DOI

      10.1126/scisignal.2005533

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-23590577, KAKENHI-PROJECT-26293106
  • [Journal Article] Homeostatic inflammation in innate immunity.2014

    • Author(s)
      K. Miyake, T. Kaisho
    • Journal Title

      Curr.Opin. Immunol.

      Volume: 30 Pages: 85-90

    • DOI

      10.1016/j.coi.2014.08.003

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-26293106
  • [Journal Article] Single-Cell Imaging of Caspase-1 Dynamics Reveals an All-or-None Inflammasome Signaling Response.2014

    • Author(s)
      Liu, T., Yamaguchi, Y., Shirasaki, Y., Shikada, K., Yamagishi, M., Hoshino, K., Kaisho, T., Takemoto, K., Suzuki, T., Kuranaga, E., Ohara, O., Miura, M.
    • Journal Title

      Cell Reports

      Volume: 8 Issue: 4 Pages: 974-982

    • DOI

      10.1016/j.celrep.2014.07.012

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J12382, KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-25440074, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-26293106, KAKENHI-PROJECT-26461465, KAKENHI-PLANNED-26114003, KAKENHI-PROJECT-24687027
  • [Journal Article] IL-27 affects helper T cell responses via regulation of PGE2 production by macrophages.2014

    • Author(s)
      Y. Sato, H. Hara, T. Okuno, N. Ozaki, S. Suzuki, T. Yokomizo, T. Kaisho, H. Yoshida.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 451 Issue: 2 Pages: 215-221

    • DOI

      10.1016/j.bbrc.2014.07.096

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116002, KAKENHI-PROJECT-25460374, KAKENHI-PROJECT-25460594, KAKENHI-PROJECT-26293106
  • [Journal Article] Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation.2014

    • Author(s)
      N. Akiyama, M. Shinzawa, M. Miyauchi, H. Yanai, R. Tateishi, Y. Shimo, D. Ohshima, K. Matsuo, I. Sasaki, K.Hoshino, G. Wu, S. Yagi, J. Inoue, T. Kaisho, T. Akiyama
    • Journal Title

      J. Exp. Med

      Volume: 211 Issue: 5 Pages: 2425-2438

    • DOI

      10.1084/jem.20140825

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-26293106
  • [Journal Article] Transcriptional Control of dendritic cell differentiation.2014

    • Author(s)
      I. Sasaki, T. Kaisho
    • Journal Title

      Curr. Top. Microbiol. Immunol.

      Volume: 381 Pages: 257-278

    • DOI

      10.1007/82_2014_378

    • ISBN
      9783319073941, 9783319073958
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-25870401, KAKENHI-PROJECT-26293106
  • [Journal Article] Invariant NKT cells induce plasmacytoid DC cross-talk with conventional DCs for efficient memory CD8+ T cell induction2013

    • Author(s)
      Shimizu K, Asakura M, Shinga J, Sato Y, Kitaha Hoshino K, Kaisho T, Schoenberger SP, Ezaki T, Fujii S
    • Journal Title

      J Immunol

      Volume: 190 Issue: 11 Pages: 5609-5619

    • DOI

      10.4049/jimmunol.1300033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23380186, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23659245, KAKENHI-PROJECT-24659904, KAKENHI-PROJECT-25861218
  • [Journal Article] Double-stranded RNA of small intestinal commensal but not pathogenic bacteria triggers TLR3-mediated IFN-β production by dendritic cells2013

    • Author(s)
      T. Kawashima, A. Kosaka, H. Yan, G. Zijin, R. Uchiyama, R. Fukui, D. Kaneko; Y. Kumagai; D.-J. You, J. Carreras, S. Uematsu, M. H. Jang, O. Takeuchi, T. Kaisho, S. Akira, K. Miyake, H. Tsutsui, T. Saito, I. Nishimura, N. M. Tsuji
    • Journal Title

      Immunity

      Volume: 38 Issue: 6 Pages: 1187-1197

    • DOI

      10.1016/j.immuni.2013.02.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24590582, KAKENHI-PROJECT-25460585
  • [Journal Article] 自然免疫とアレルギー2013

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー

      Volume: 62(7) Pages: 789-796

    • Data Source
      KAKENHI-PROJECT-23390124
  • [Journal Article] Double-stranded RNA of small intestinal commensal but not pathogenic bacteria triggers TLR3-mediated IFN-β production by dendritic cells2013

    • Author(s)
      T. Kawashima, A. Kosaka, H. Yan, G. Zijin, R. Uchiyama, R. Fukui, D. Kaneko; Y. Kumagai; D.-J. You, J. Carreras, S. Uematsu, M. H. Jang, O. Takeuchi, T. Kaisho, S. Akira, K. Miyake, H. Tsutsui, T. Saito, I. Nishimura, N. M. Tsuji
    • Journal Title

      Immunity

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] Critical roles of a dendritic cell subset expressing a chemokine receptor, XCR12013

    • Author(s)
      C. Yamazaki, M. Sugiyama, T. Ohta, H. Hemmi, E. Hamada, I. Sasaki, Y. Fukuda, T. Yano, M. Nobuoka, T. Hirashima, A. Iizuka, K. Sato, T. Tanaka, K. Hoshino, T. Kaisho
    • Journal Title

      J. Immunol

      Volume: 190 Issue: 12 Pages: 6071-6082

    • DOI

      10.4049/jimmunol.1202798

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23590577, KAKENHI-PROJECT-23659245, KAKENHI-PROJECT-24590460, KAKENHI-PROJECT-25293117, KAKENHI-PROJECT-25870401
  • [Journal Article] Enhanced Apoptosis by Disruption of the STAT3-I κ B-ζ Signaling Pathway in Epithelial Cells Induces Sjogren' S Syndrome-like Autoimmune Disease.2013

    • Author(s)
      大熊敦史
    • Journal Title

      Immunity

      Volume: 38 Issue: 3 Pages: 450-460

    • DOI

      10.1016/j.immuni.2012.11.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04191, KAKENHI-ORGANIZER-21117001, KAKENHI-PLANNED-21117004, KAKENHI-PROJECT-21390088, KAKENHI-PROJECT-22590345, KAKENHI-PROJECT-22590444, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23659245, KAKENHI-PROJECT-23659541, KAKENHI-PROJECT-24390076, KAKENHI-PLANNED-21117003
  • [Journal Article] Innate immunity and allergy.2013

    • Author(s)
      T. Kaisho
    • Journal Title

      Allergy

      Volume: 62(7) Pages: 789-796

    • NAID

      110009635084

    • Data Source
      KAKENHI-PLANNED-21117003
  • [Journal Article] Panthogen sensors and chemokine receptors in dendric cell subsets.2012

    • Author(s)
      T. Kaisho
    • Journal Title

      Vaccine

      Volume: 30 Pages: 7652-7657

    • URL

      http://dx.doi.org/10.1016/j.vaccine.2012.10.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] Treml4, an Ig Superfamily Member, Mediates Presentation of Several Antigens to T Cells In Vivo, Including Protective Immunity to HER2 Protein2012

    • Author(s)
      Hiroaki Hemmi, Neeha Zaidi, Bei Wang, Ines Matos, Christopher Fiorese, Ashira Lubkin, Lori Zbytnuik, Koji Suda, Kenneth Zhang, Masaki Noda, Tsuneyasu Kaisho, Ralph M. Steinman, and Juliana Idoyaga
    • Journal Title

      J Immunol

      Volume: 188 Issue: 3 Pages: 1147-1155

    • DOI

      10.4049/jimmunol.1102541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790376, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23659245, KAKENHI-PROJECT-23659868, KAKENHI-PLANNED-21117003
  • [Journal Article] CD8 陽性樹状細胞サブセットの動的制御機構の解析2012

    • Author(s)
      邊見弘明, 山崎千尋, 星野克明, 改正恒康
    • Journal Title

      Cytometry Research

      Volume: 22(1) Pages: 31-35

    • NAID

      10030199789

    • Data Source
      KAKENHI-PROJECT-23390124
  • [Journal Article] A chemokine system in CD8 positive dendritic cells2012

    • Author(s)
      邊見弘明、山崎千尋、星野克明、改正恒康
    • Journal Title

      Cytometry Research

      Volume: 22 Pages: 31-35

    • NAID

      10030199789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] 樹状細胞サブセットの機能と生理的意義.2012

    • Author(s)
      佐々木泉、改正恒康
    • Journal Title

      炎症と免疫

      Volume: 20(1) Pages: 21-26

    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] CD8陽性樹状細胞サブセットの動的制御機構の解析2012

    • Author(s)
      邊見弘明、山崎千尋、星野克明、改正恒康
    • Journal Title

      A chemokine system in CD8 positive dendritic cells. Cytometry Research

      Volume: 22(1) Pages: 31-35

    • NAID

      10030199789

    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] 樹状細胞サブセットの機能と生理的意義2012

    • Author(s)
      佐々木泉, 改正恒康
    • Journal Title

      炎症と免疫

      Volume: 20(1) Pages: 21-26

    • Data Source
      KAKENHI-PROJECT-23390124
  • [Journal Article] Pathogen sensors and chemokine receptors in dendritic cell subsets2012

    • Author(s)
      T. Kaisho
    • Journal Title

      Vaccine

      Volume: 30 Issue: 52 Pages: 7652-7657

    • DOI

      10.1016/j.vaccine.2012.10.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23659245, KAKENHI-PLANNED-21117003
  • [Journal Article] Spi-B is critical for plasmacytoid dendritic cell function and development2012

    • Author(s)
      Sasaki, K. Hoshino, T. Sugiyama, C. Yamazaki, T. Yano, A. Iizuka, H. Hemmi, T. Tanaka, M. Saito, M. Sugiyama, Y. Fukuda, T. Ohta, K. Sato, A. Ainai, T. Suzuki, H. Hasegawa, N. Toyama-Sorimachi, H. Kohara, T. Nagasawa, T. Kaisho
    • Journal Title

      Blood

      Volume: 120 Issue: 24 Pages: 4733-4743

    • DOI

      10.1182/blood-2012-06-436527

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21117001, KAKENHI-PROJECT-22390096, KAKENHI-PROJECT-22590444, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23590577, KAKENHI-PROJECT-23659245, KAKENHI-PROJECT-23790454, KAKENHI-PROJECT-24590460, KAKENHI-PLANNED-21117003, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003
  • [Journal Article] Differential MyD88/IRAK4 requirements for cross-priming and tumor rejection induced by heat shock protein 70-model antigen fusion protein.2012

    • Author(s)
      S. Mizukami, C. Kajiwara, M. Tanaka, T. Kaisho, H. Udono.
    • Journal Title

      Cancer Sci.

      Volume: 103(5) Pages: 851-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] Differential MyD88/IRAK4 requirements for cross-priming and tumor rejection induced by hsp70-model Ag fusion protein.2012

    • Author(s)
      MizukamiS, KajiwaraC, TanakaM, KaishoT, Udono H.
    • Journal Title

      Cancer Science

      Volume: 103 Issue: 5 Pages: 851-859

    • DOI

      10.1111/j.1349-7006.2012.02233.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22501027, KAKENHI-PROJECT-23390095, KAKENHI-PROJECT-23390124, KAKENHI-PLANNED-21117003
  • [Journal Article] 樹状細胞サブセットの機能と生理的意義2012

    • Author(s)
      佐々木泉、改正恒康
    • Journal Title

      炎症と免疫

      Volume: 20 Pages: 21-26

    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] 樹状細胞に関する私の初仕事2012

    • Author(s)
      改正恒康
    • Journal Title

      アレルギ - の臨床

      Volume: 32(12) Pages: 13-13

    • Data Source
      KAKENHI-PROJECT-23390124
  • [Journal Article] Lactococcus lactis subsp. cremoris FC triggers IFN-γ production from NK and T cells via IL-12 and IL-182012

    • Author(s)
      A. Kosaka, H. Yan, S. Ohashi, Y. Gotoh, A. Sato, H. Tsutsui, T. Kaisho, T. Toda, Tsuji NM
    • Journal Title

      Int Immunopharmacol

      Volume: 14(4) Issue: 4 Pages: 729-33

    • DOI

      10.1016/j.intimp.2012.10.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23659245, KAKENHI-PLANNED-21117003
  • [Journal Article] The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells2012

    • Author(s)
      Kanaya, T., Hase, K., Takahashi, D., Fukuda, S., Hoshino, K., Sasaki, I., Hemmi, H., Knoop, K. A., Kumar, N., Sato, M., Katsuno, T., Yokosuka, O., Toyooka, K., Nakai, K., Sakamoto, A., Kitahara, Y., Jinnohara, T., McSorley, S. J., Kaisho, T., Williams, I. R., and Ohno, H.
    • Journal Title

      Nat Immunol

      Volume: 13 Issue: 8 Pages: 729-736

    • DOI

      10.1038/ni.2352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590444, KAKENHI-PROJECT-22689017, KAKENHI-PROJECT-22770063, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23659245, KAKENHI-PROJECT-23790550, KAKENHI-PROJECT-24249029, KAKENHI-PROJECT-24380072, KAKENHI-PROJECT-24658129, KAKENHI-PROJECT-24687007, KAKENHI-PLANNED-20113003, KAKENHI-PLANNED-21117003, KAKENHI-PUBLICLY-24117524, KAKENHI-PUBLICLY-24117723
  • [Journal Article] Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo2011

    • Author(s)
      H.Takagi
    • Journal Title

      Immunity

      Volume: 35 Issue: 6 Pages: 958-971

    • DOI

      10.1016/j.immuni.2011.10.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23659245
  • [Journal Article] 樹状細胞サブセット機能を制御する分子機構.2011

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー

      Volume: 60(5) Pages: 559-565

    • NAID

      110008661490

    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] 免疫アジュバントの特性とTh細胞分化誘導. New insights into immune adjuvants and induction of Th cell differentiation2011

    • Author(s)
      大田友和、改正恒康
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 56 Pages: 558-563

    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] 樹状細胞サブセット機能を制御する分子機構2011

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー 60(5)

      Pages: 559-565

    • NAID

      110008661490

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 免疫アジュバントの特性とTh 細胞分化誘導. New insights into immune adjuvants and induction of Th cell differentiation2011

    • Author(s)
      大田友和、改正恒康
    • Journal Title

      臨床免疫・アレルギー科 Clinicl Immunology & Allergology

      Volume: 56(5) Pages: 558-563

    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] 樹状細胞サブセット機能を制御する分子機構2011

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー

      Volume: 60 Pages: 559-565

    • NAID

      110008661490

    • Data Source
      KAKENHI-PLANNED-21117003
  • [Journal Article] 樹状細胞サブセット機能を制御する分子機構2011

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー

      Volume: 60(5) Pages: 559-565

    • NAID

      110008661490

    • Data Source
      KAKENHI-PROJECT-23390124
  • [Journal Article] 免疫アジュバントの特性と Th 細胞分化誘導2011

    • Author(s)
      大田友和, 改正恒康
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 56(5) Pages: 558-563

    • NAID

      40019087195

    • Data Source
      KAKENHI-PROJECT-23390124
  • [Journal Article] PDLIM2 inhibits T helper cell development and granulomatous inflammation through degradation of STAT32011

    • Author(s)
      T.Tanaka
    • Journal Title

      J.Immunol

      Volume: 188 Issue: 202 Pages: 141-151

    • DOI

      10.1126/scisignal.2001637

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21117003, KAKENHI-PROJECT-23390015, KAKENHI-PROJECT-23390124, KAKENHI-PROJECT-23590577, KAKENHI-PROJECT-23659245, KAKENHI-PROJECT-23790067
  • [Journal Article] 樹状細胞サブセット機能を制御する分子機構2011

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー

      Volume: 60 Pages: 559-565

    • NAID

      110008661490

    • Data Source
      KAKENHI-PROJECT-23659245
  • [Journal Article] Conservation of a chemokine system, XCR1 and its ligand, XCL1, between human and mice2010

    • Author(s)
      T.Kaisho
    • Journal Title

      Biochem.Biophys.Res.Commun. 397

      Pages: 756-761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸認識Toll様受容体刺激による樹状細胞からのI型インターフェロン産生誘導機構2010

    • Author(s)
      改正恒康
    • Journal Title

      医学のあゆみ

      Volume: 234 Pages: 357-363

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸に対する樹状細胞応答の制御機構2010

    • Author(s)
      改正恒康
    • Journal Title

      炎症と免疫

      Volume: 18 Pages: 234-237

    • Data Source
      KAKENHI-PROJECT-21659123
  • [Journal Article] 樹状細胞による獲得免疫の制御2010

    • Author(s)
      佐々木泉、改正恒康
    • Journal Title

      侵襲と免疫 19(2)

      Pages: 11-16

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Molecular mechanisms for plasmacytoid dendritic cell function and development2010

    • Author(s)
      T.Kaisho
    • Journal Title

      Vaccine

      Volume: 28 Pages: 8046-8047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Journal Article] 核酸系免疫アジュバントの特性と作用機構2010

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー 59(1)

      Pages: 14-19

    • NAID

      110007539072

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Toll-like receptorによる核酸認識と応答機構2010

    • Author(s)
      佐々木泉、改正恒康
    • Journal Title

      ファルマシア 46(1)

      Pages: 27-31

    • NAID

      110009867577

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸に対する樹状細胞応答の制御機構2010

    • Author(s)
      改正恒康
    • Journal Title

      炎症と免疫 18(3)

      Pages: 234-237

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸認識Toll様受容体刺激による樹状細胞からのI型インターフェロン産生誘導機構2010

    • Author(s)
      改正恒康
    • Journal Title

      医学のあゆみ

      Volume: 234 Pages: 357-363

    • Data Source
      KAKENHI-PLANNED-21117003
  • [Journal Article] Cutting edge : Critical role of IKB Kinase a in TLR7/9-Induced type I interferon production by conventional dendritic cells2010

    • Author(s)
      T.Kaisho
    • Journal Title

      J. Immunol 184

      Pages: 3341-3345

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production2010

    • Author(s)
      T.Kaisho
    • Journal Title

      Arthritis Rheum. 62

      Pages: 2073-2085

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸に対する樹状細胞応答の制御機構2010

    • Author(s)
      改正恒康
    • Journal Title

      炎症と免疫

      Volume: 18 Pages: 234-237

    • Data Source
      KAKENHI-PLANNED-21117003
  • [Journal Article] Molecular mechanisms for plasmacytoid dendritic cell function and development2010

    • Author(s)
      T.Kaisho
    • Journal Title

      Vaccine

      Volume: 28 Pages: 8046-8047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Molecular mechanisms for plasmacytoid dendritic cell function and development2010

    • Author(s)
      T.Kaisho
    • Journal Title

      Vaccine 28

      Pages: 8046-8047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] TLRシグナルによる1型インターフェロンの産生2010

    • Author(s)
      星野克明、改正恒康
    • Journal Title

      臨床免疫・アレルギー科 54(4)

      Pages: 465-471

    • NAID

      40017376787

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Inhibitor of IkappaB kinase activity, BAY11-7082, interferes with the interferon regulatory factor 7 nuclear translocation and type I IFN production by plasmacytoid dendritic cells2010

    • Author(s)
      T.Kaisho
    • Journal Title

      Arthritis Research Therap 12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸認識[Doll様受容体刺激による樹状細胞からの1型インターフェロン産生誘導機構2010

    • Author(s)
      改正恒康
    • Journal Title

      医学のあゆみ 234(5)

      Pages: 357-363

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Molecular mechanisms for plasmacytoid dendritic cell function and development2010

    • Author(s)
      T.Kaisho
    • Journal Title

      Vaccine

      Volume: 28 Pages: 8046-8047

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Journal Article] Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation2010

    • Author(s)
      T.Kaisho
    • Journal Title

      J.Exp.Med. 207

      Pages: 721-730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸に対する樹状細胞応答の制御機構2010

    • Author(s)
      改正恒康
    • Journal Title

      炎症と免疫

      Volume: 18 Pages: 234-237

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice2010

    • Author(s)
      T.Kaisho
    • Journal Title

      J.Clin.Invest. 120

      Pages: 115-126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸認識Toll様受容体刺激による樹状細胞からのI型インターフェロン産生誘導機構2010

    • Author(s)
      改正恒康
    • Journal Title

      医学のあゆみ

      Volume: 234 Pages: 357-363

    • Data Source
      KAKENHI-PROJECT-21659123
  • [Journal Article] The study of innate immunity in Japan : a historical perspective2009

    • Author(s)
      改正恒康
    • Journal Title

      Int.Immunol. 21

      Pages: 313-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] TRAF6 is required for generation of the B-1a B cell compartment as well as T cell-dependent and -independent humoral immune responses2009

    • Author(s)
      T.Kaisho
    • Journal Title

      PLoS ONE 4(3)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 樹状細胞におけるpatternrecognitionreceptorと1型インターフェロンの役割2009

    • Author(s)
      星野克明、改正恒康
    • Journal Title

      炎症と免疫 18(1)

      Pages: 38-43

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸系免疫アジュバントの特性と作用機構2009

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー 59

      Pages: 14-19

    • NAID

      110007539072

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸系免疫アジュバントの特性と作用機構2009

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー 59

      Pages: 14-19

    • NAID

      110007539072

    • Data Source
      KAKENHI-PROJECT-21659123
  • [Journal Article] The study of innate immunity in Japan : a historical perspective.2009

    • Author(s)
      T.Kaisho
    • Journal Title

      Int.Immunolo 21

      Pages: 313-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Journal Article] The study of innate immunity in Japan : a historical perspective.2009

    • Author(s)
      T.Kaisho
    • Journal Title

      Int.Immunolo 21

      Pages: 313-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21022048
  • [Journal Article] 核酸系免疫アジュバントの特性と作用機構2009

    • Author(s)
      改正恒康
    • Journal Title

      アレルギー 59

      Pages: 14-19

    • NAID

      110007539072

    • Data Source
      KAKENHI-PLANNED-21117003
  • [Journal Article] The study of innate immunity in Japan : a historical perspective2009

    • Author(s)
      T.Kaisho
    • Journal Title

      Int.Immunol. 21

      Pages: 313-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Journal Article] 第10回国際樹状細胞シンポジウム学会レポート2009

    • Author(s)
      改正恒康
    • Journal Title

      感染炎症免疫 39(2)

      Pages: 154-156

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] The study of innate immunity in Japan : a historical perspective2009

    • Author(s)
      T.Kaisho, K. Takeda
    • Journal Title

      Int.Immunol. 21

      Pages: 313-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgGl production2009

    • Author(s)
      T.Kaisho
    • Journal Title

      Mol.Immunol. 46(7)

      Pages: 1278-1288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Id2-, RORyt-, and LT(3R-independent initiation of lymphoid organogenesis in ocular immunity2009

    • Author(s)
      T.Kaisho
    • Journal Title

      J.Exp.Med. 206

      Pages: 2351-2364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effects in mouse sepsis model2009

    • Author(s)
      T.Kaisho
    • Journal Title

      British J Pharmacology 157

      Pages: 1250-1262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] The study of innate immunity in Japan : a historical perspective2009

    • Author(s)
      T.Kaisho
    • Journal Title

      Int.Immunol. 21

      Pages: 313-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Journal Article] 核酸系免疫アジュバントによる樹状細胞活性化機構とその病理的意義2008

    • Author(s)
      改正恒康
    • Journal Title

      実験医学増刊樹状細胞による免疫制御と臨床応用 26

      Pages: 59-64

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Immunoadjuvant effects of polyadenylic-polyuridylic acids through TLR3 and TLR72008

    • Author(s)
      T.Kaisho
    • Journal Title

      Int.Immunol. 20

      Pages: 1-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Host-pathogen interactions (Editorial)2008

    • Author(s)
      T. Kaisho, H.Wagner
    • Journal Title

      Curr.Opin.Immunol. 20

      Pages: 369-370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Host-pathogen interactions(Editorial)2008

    • Author(s)
      改正恒康
    • Journal Title

      Curr.Opin.Immunol. 20

      Pages: 369-370

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Turning NF-κB and IRFs on and off in DC2008

    • Author(s)
      改正恒康
    • Journal Title

      Trends Immunol. 29

      Pages: 329-336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 「研究成果報告書概要(欧文)」より2008

    • Author(s)
      T. Kaisho
    • Journal Title

      Frontiers in Bioscience 13

      Pages: 6034-6042

    • Data Source
      KAKENHI-PROJECT-18590483
  • [Journal Article] Type I interferon production by nucleic acid-stimulated dendritic cells.2008

    • Author(s)
      T. Kaisho
    • Journal Title

      Frontiers in Bioscience 13

      Pages: 6034-6042

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Journal Article] TLRシグナルにおけるIKKファミリーの役割-IKKαを中心として2008

    • Author(s)
      星野克明、改正恒康
    • Journal Title

      AnnualReview免疫2008

      Pages: 61-69

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Host-pathogen interactions(Editorial)2008

    • Author(s)
      改正恒康
    • Journal Title

      Curr. Opin. Immunol 20

      Pages: 369-370

    • Data Source
      KAKENHI-PROJECT-20060033
  • [Journal Article] 形質細胞様樹状細胞による1型インターフェロン産生機序2008

    • Author(s)
      杉山孝弘、改正恒康
    • Journal Title

      臨床免疫・アレルギー科 49(4)

      Pages: 470-476

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 核酸系免疫アジュバントによる樹状細胞活性化機構とその病理的意義2008

    • Author(s)
      改正恒康
    • Journal Title

      実験医学増刊樹状細胞による免疫制御と臨床応用 26(20)

      Pages: 59-64

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Turning NF-κB and IRFs on and off in DC2008

    • Author(s)
      改正恒康
    • Journal Title

      Trends Immunol 29

      Pages: 329-336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Journal Article] Type I interferon production by nucleic acid-stimulated dendritic cells2008

    • Author(s)
      改正恒康
    • Journal Title

      Front.Biosci. 13

      Pages: 6034-6042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon2008

    • Author(s)
      T.Kaisho
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 105

      Pages: 2993-2998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity2008

    • Author(s)
      T.Kaisho
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 105

      Pages: 20446-20451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] 樹状細胞における核酸系免疫アジュバント認識機構とその病理的意義2008

    • Author(s)
      矢野貴公、改正恒康
    • Journal Title

      医学のあゆみ 227(5)

      Pages: 398-403

    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Turning NF-κB and IRFs on and off in DC2008

    • Author(s)
      改正恒康
    • Journal Title

      Trends Immunol. 29

      Pages: 329-336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Journal Article] Type I interferon production by nucleic acid-stimulated dendritic cells2008

    • Author(s)
      改正恒康
    • Journal Title

      Front. Biosci. 13

      Pages: 6034-6042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Journal Article] 核酸系免疫アジュバントによる樹状細胞活性化機構とその病理的意義2008

    • Author(s)
      改正恒康
    • Journal Title

      実験医学増刊樹状細胞による免疫制御と臨床応用 26

      Pages: 59-64

    • Data Source
      KAKENHI-PROJECT-20060033
  • [Journal Article] 核酸系免疫アジュバントによる樹状細胞活性化機構とその病理的意義2008

    • Author(s)
      改正恒康
    • Journal Title

      実験医学増刊樹状細胞による免疫制御と臨床応用 26

      Pages: 59-64

    • Data Source
      KAKENHI-PROJECT-19041070
  • [Journal Article] Type I interferon production by nucleic acid-stimulated dendritic cells2008

    • Author(s)
      T.Kaisho
    • Journal Title

      Front.Biosci. 13

      Pages: 6034-6042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Host-pathogen interactions(Editorial)2008

    • Author(s)
      改正恒康
    • Journal Title

      Curr. Opin. Immunol. 20

      Pages: 369-370

    • Data Source
      KAKENHI-PROJECT-19041070
  • [Journal Article] Type I interferon production by nucleic acid-stimulated dendritic cells2008

    • Author(s)
      改正恒康
    • Journal Title

      Front. Biosci. 13

      Pages: 6034-6042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Journal Article] Toll-like receptor signaling is impaired in dendritic cells from patients with X-linked agammagloblinemia2008

    • Author(s)
      T.Kaisho
    • Journal Title

      Clin.Immunol. 126

      Pages: 148-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Turning NF-KB and IRFs on and off in DC2008

    • Author(s)
      T.Kaisho, T.Tanaka
    • Journal Title

      Trends Immunol. 29

      Pages: 329-336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Nucleic acid sensing Toll-like receptors in dendritic cells2008

    • Author(s)
      K.Hoshino, T.Kaisho
    • Journal Title

      Curr.Opin.Immunol. 20

      Pages: 408-413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Journal Article] Principles of innate immunity2007

    • Author(s)
      T. Kaisho S. Akira
    • Journal Title

      Rheumatology vol.1

      Pages: 143-150

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Journal Article] TLR function and signaling2006

    • Author(s)
      T.Kaisho
    • Journal Title

      J. Allergy Clin. Immunol. 117・5

      Pages: 979-987

    • Data Source
      KAKENHI-PROJECT-17047046
  • [Journal Article] TLR function and signaling2006

    • Author(s)
      T. Kaisho
    • Journal Title

      J. Allergy Clin. Immunol. 117・5

      Pages: 979-987

    • Data Source
      KAKENHI-PROJECT-18590483
  • [Journal Article] TLR function and signaling.2006

    • Author(s)
      T. Kaisho
    • Journal Title

      J. Allergy Clin. Immunol. 117

      Pages: 979-987

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Journal Article] Pleiotropic function of Toll-like receptors.2005

    • Author(s)
      T.Kaisho, S.Akira
    • Journal Title

      Microbes and Infection (in press)

    • Data Source
      KAKENHI-PROJECT-16021231
  • [Journal Article] Pleiotropic function of Toll-like receptors.2005

    • Author(s)
      T.Kaisho, S.Akira.
    • Journal Title

      Microbes and Infection (in press)

    • Data Source
      KAKENHI-PROJECT-16590403
  • [Journal Article] Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.2004

    • Author(s)
      S.S.Diebold, T.Kaisho 他
    • Journal Title

      Science 303

      Pages: 1529-1531

    • Data Source
      KAKENHI-PROJECT-16590403
  • [Journal Article] Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.2004

    • Author(s)
      S.S.Diebold, T.Kaisho 他
    • Journal Title

      Science 303

      Pages: 1529-1531

    • Data Source
      KAKENHI-PROJECT-16021231
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志、改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2009-11-05
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2009-11-05
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Number
      2009-112250
    • Filing Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-21022048
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2009-11-05
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志、改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2009-11-05
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Number
      2009-112250
    • Filing Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2009-11-05
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2009-11-05
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2009-11-05
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Patent] 創傷治療剤及びそのスクリーニング方法2009

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2009-11-05
    • Overseas
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Patent] I型IFNの産生阻害剤、及びその探索方法2008

    • Inventor(s)
      改正恒康, 星野克明, 杉山孝弘
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Patent] I型IFNの産生阻害剤、及びその探索方法2008

    • Inventor(s)
      改正恒康、星野克明、杉山孝弘
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Patent] I型IFNの産生阻害剤、及びその探索方法2008

    • Inventor(s)
      改正恒康, 星野克明, 杉山孝弘
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Patent] I型IFNの産生阻害剤、及びその探索方法2008

    • Inventor(s)
      改正恒康, 星野克明, 杉山孝弘
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Patent] p65媒介シグナル伝達の調節剤及びそのスクリーニング方法2007

    • Inventor(s)
      田中 貴志,改正 恒康, Michael J. Grusby
    • Industrial Property Rights Holder
      独立行政法人理化学研究所 President and Fellows of Harvard College
    • Filing Date
      2007-03-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Patent] p65媒介シグナル伝達の調節剤及びそのスクリーニング方法2006

    • Inventor(s)
      田中貴志 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2006-03-21
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Patent] p65媒介シグナル伝達の調節剤及びそのスクリーニング方法2006

    • Inventor(s)
      田中貴志, 改正恒康
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2006-03-21
    • Data Source
      KAKENHI-PROJECT-17047046
  • [Patent] インターフェロン-α制御剤2005

    • Inventor(s)
      改正恒康, 星野克明
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2005-06-03
    • Data Source
      KAKENHI-PROJECT-16590403
  • [Patent] インターフェロン-α制御剤2005

    • Inventor(s)
      改正 恒康, 星野 克明
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2005-06-03
    • Data Source
      KAKENHI-PROJECT-17016082
  • [Patent] インターフェロンーα制御剤2005

    • Inventor(s)
      改正恒康, 星野克明
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2005-06-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590403
  • [Patent] インターフェロン-α制御剤2005

    • Inventor(s)
      改正 恒康, 星野 克明
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2005-06-03
    • Data Source
      KAKENHI-PROJECT-17047046
  • [Presentation] Memory T helper cell differentiation regulated by a type 1 conventional dendritic cell subpopulation.2024

    • Author(s)
      K. Ohki, Y. Matsushima, S. Hojyo, T. Kaisho, K. Tokoyoda.
    • Organizer
      第52回本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissueresident macrophages.2024

    • Author(s)
      I. Sasaki, Y. Fukuda-Ohta, S. Morita, D. Okuzaki, T. Kato, K. Furukawa, T. Kaisho.
    • Organizer
      第52回本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5L/AIMhi hepatic macrophages.2024

    • Author(s)
      R. Sato, K. Liu, T. Shibata, R. Fukui, K. Hoshino, T. Kondo, T. Miyazaki, T. Kaisho, K. Miyake.
    • Organizer
      第52回本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Generation and characterization of thePsmb8 G201V mutation knock-in mice as a model for Nakajo-Nishimura syndrome2024

    • Author(s)
      T. Hara, T. Kato, J. Hamazaki, A. Kinoshita, Y. Inaba, I. Sasaki, K. -I. Yoshiura, M. Jinnin, T. Kaisho, N. Kanazawa.
    • Organizer
      APSID-JSIAD 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Which subset of dendritic cells is critical to the effect of HSV-1 oncolytic virus therapy?2024

    • Author(s)
      S. Uchida, T. Seya, S. Akira, K. Sato, T. Kaisho, R. Fukui, K. Miyake, T. Todo, N. Kadowaki.
    • Organizer
      第52回本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissueresident macrophages.2024

    • Author(s)
      I. Sasaki, Y. Fukuda-Ohta, S. Morita, D. Okuzaki, T. Kato, K. Furukawa, T. Kaisho.
    • Organizer
      第52回本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5L/AIMhi hepatic macrophages.2024

    • Author(s)
      R. Sato, K. Liu, T. Shibata, R. Fukui, K. Hoshino, T. Kondo, T. Miyazaki, T. Kaisho, K. Miyake.
    • Organizer
      第52回本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Memory T helper cell differentiation regulated by a type 1 conventional dendritic cell subpopulation.2024

    • Author(s)
      K. Ohki, Y. Matsushima, S. Hojyo, T. Kaisho, K. Tokoyoda.
    • Organizer
      第52回本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Generation and characterization of thePsmb8 G201V mutation knock-in mice as a model for Nakajo-Nishimura syndrome2024

    • Author(s)
      T. Hara, T. Kato, J. Hamazaki, A. Kinoshita, Y. Inaba, I. Sasaki, K. -I. Yoshiura, M. Jinnin, T. Kaisho, N. Kanazawa.
    • Organizer
      APSID-JSIAD 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Which subset of dendritic cells is critical to the effect of HSV-1 oncolytic virus therapy?2024

    • Author(s)
      S. Uchida, T. Seya, S. Akira, K. Sato, T. Kaisho, R. Fukui, K. Miyake, T. Todo, N. Kadowaki.
    • Organizer
      第52回本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Generation and characterization of thePsmb8 G201V mutation knock-in mice as a model for Nakajo-Nishimura syndrome2023

    • Author(s)
      T. Hara, T. Kato, J. Hamazaki, A. Kinoshita, Y. Inaba, I. Sasaki, K. -I. Yoshiura, M. Jinnin, T. Kaisho, N. Kanazawa.
    • Organizer
      ISID 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] 生体内マクロファージにおけるパイリンインフラマソーム活性化機構の解明.2023

    • Author(s)
      加治汐梨、佐々木泉、古田有希、加藤喬、西山奈央子、山本明日美、北野雅之、改正恒康.
    • Organizer
      第30回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Novel model mice of human inborn errors of immunity manifesting autoinflammation, autoimmunity and/or immunodeficiency.2023

    • Author(s)
      T. Kaisho.
    • Organizer
      The 2nd International Symposium of Clinical Immunology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue resident macrophages.2023

    • Author(s)
      I. Sasaki, N. W-. Nishiyama, D. Okuzaki, S. Morita, T.Kato, A.Yamamoto, K. Furukawa, T.Kaisho.
    • Organizer
      第30回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Human inborn errors of immunity model mice for autoinflammation,autoimmunity and/or immunodeficiency.2023

    • Author(s)
      T. Kaisho.
    • Organizer
      JSICR/MMCB Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue resident macrophages.2023

    • Author(s)
      I. Sasaki, N. W-. Nishiyama, D. Okuzaki, S. Morita, T.Kato, A.Yamamoto, K. Furukawa, T.Kaisho.
    • Organizer
      第30回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Spi-Bは圧負荷に対する心臓の代償応答過程においてマクロファージサブセットの構成を制御して抗炎症性に機能する2023

    • Author(s)
      近藤 稔和、木村 章彦、佐々木 泉、石田 裕子、野坂 みずほ、樽谷 玲、國中 由美、加藤 喬、改正 恒康
    • Organizer
      第44回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Spi-Bは圧負荷に対する心臓の代償応答過程においてマクロファージサブセットの構成を制御して抗炎症性に機能する2023

    • Author(s)
      近藤 稔和、木村 章彦、佐々木 泉、石田 裕子、野坂 みずほ、樽谷 玲、國中 由美、加藤 喬、改正 恒康
    • Organizer
      第44回日本炎症・再生医学会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] 生体内マクロファージにおけるパイリンインフラマソーム活性化機構の解明.2023

    • Author(s)
      加治汐梨、佐々木泉、古田有希、加藤喬、西山奈央子、山本明日美、北野雅之、改正恒康.
    • Organizer
      第30回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Impairment of plasma cell generation in mice carrying a proteasome subunit β1i missense mutation derived from patients with autoinflammation and adaptive immune deficiency.2023

    • Author(s)
      T. Kato, A. Yamamoto, I. Sasaki, N. Wakaki-Nishiyama, H. Hemmi, N. Kanazawa, W. Ise, T. Kaisho.
    • Organizer
      Japan and Australia Meeting on Cell Death 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Generation and characterization of thePsmb8 G201V mutation knock-in mice as a model for Nakajo-Nishimura syndrome2023

    • Author(s)
      T. Hara, T. Kato, J. Hamazaki, A. Kinoshita, Y. Inaba, I. Sasaki, K. -I. Yoshiura, M. Jinnin, T. Kaisho, N. Kanazawa.
    • Organizer
      ISID 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] γδT17 cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation by commensals.2023

    • Author(s)
      S. Komiyama, D. Takahashi, T. Kaisho, K. Hase.
    • Organizer
      18th International Congress of Immunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Impairment of plasma cell generation in mice carrying a proteasome subunit β1i missense mutation derived from patients with autoinflammation and adaptive immune deficiency.2023

    • Author(s)
      T. Kato, A. Yamamoto, I. Sasaki, N. Wakaki-Nishiyama, H. Hemmi, N. Kanazawa, W. Ise, T. Kaisho.
    • Organizer
      Japan and Australia Meeting on Cell Death 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18222
  • [Presentation] Human inborn errors of immunity model mice for autoinflammation,autoimmunity and/or immunodeficiency.2023

    • Author(s)
      T. Kaisho.
    • Organizer
      JSICR/MMCB Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Novel model mice of human inborn errors of immunity manifesting autoinflammation, autoimmunity and/or immunodeficiency.2023

    • Author(s)
      T. Kaisho.
    • Organizer
      The 2nd International Symposium of Clinical Immunology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] γδT17 cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation by commensals.2023

    • Author(s)
      S. Komiyama, D. Takahashi, T. Kaisho, K. Hase.
    • Organizer
      18th International Congress of Immunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] γδT cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation by commensals and exacerbates autoimmune ncephaomyelitis.2022

    • Author(s)
      S. Komiyama, D. Takahashi, T.Kaisho, K. Hase.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] γδT cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation by commensals and exacerbates autoimmune ncephaomyelitis.2022

    • Author(s)
      S. Komiyama, D. Takahashi, T.Kaisho, K. Hase.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] 遺伝子改変マウスを用いた組織常在マクロファージの免疫学的解析2022

    • Author(s)
      加治汐梨、佐々木泉、加藤喬、西山奈央子、山本明日美、脇村一輝、北野雅之、改正恒康
    • Organizer
      第29回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] The role of Rnase T2 in macrophage homeostasis.2022

    • Author(s)
      R.Sato, K.Liu, T.Shibata, R.Fukui, K.Hoshino, T.Kaisho, K.Miyake.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] γδT cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation by commensals and exacerbates autoimmune ncephaomyelitis.2022

    • Author(s)
      S. Komiyama, D. Takahashi, T.Kaisho, K. Hase.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] The role of Rnase T2 in macrophage homeostasis.2022

    • Author(s)
      R. Sato, K.Liu, T.Shibata, R.Fukui, K.Hoshino, T.Kaisho, K.Miyake.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] 遺伝子改変マウスを用いた組織常在マクロファージの免疫学的解析2022

    • Author(s)
      加治汐梨、佐々木泉、加藤喬、西山奈央子、山本明日美、脇村一輝、北野雅之、改正恒康
    • Organizer
      第29回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Activation of type 1 interferon signaling in dendritic cells and T cells of the mouse model of COPA syndrome.2022

    • Author(s)
      T.Kato, R.Yamasaki, N.W-Nishiyama. I.Sasaki, S.Kaji, K.Murakami, H.Hemmi, Y.Honda, K.Izawa, Y.Otsuki, T.Matsubayashi, R.Nishikomori, T.Kaisho.
    • Organizer
      第29回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Type 1 conventional dendritic cells of bone marrow assistthe prograession of multiple myeloma and consist of tumor microenvironment in the transplanted Vk*MYC mouse model.2022

    • Author(s)
      S.Suzuki, S.Tsuda, T.Takubo, H.Toyoshima, M.Yoshino, T.Kaisho, T.Fukuda, K.Tokoyoda.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] 遺伝子改変マウスを用いた組織常在マクロファージの免疫学的解析2022

    • Author(s)
      加治汐梨、佐々木泉、加藤喬、西山奈央子、山本明日美、脇村一輝、北野雅之、改正恒康
    • Organizer
      第29回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Dendritic and T cell abnormalities in an autoinflammatory disease with interstitial lung disease and type 1 interferonopathy caused by a disability of retrongrade protein trafficking.2022

    • Author(s)
      T. Kato, I.Sasaki, H. Hemmi, Y. Honda. K. Izawa, R. Nishikomori, T. Kaisho.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Type 1 conventional dendritic cells of bone marrow assistthe prograession of multiple myeloma and consist of tumor microenvironment in the transplanted Vk*MYC mouse model.2022

    • Author(s)
      S.Suzuki, S.Tsuda, T.Takubo, H.Toyoshima, M.Yoshino, T.Kaisho, T.Fukuda, K.Tokoyoda.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Model mice of human inborn errors of immunity showing mixed manifestations of aouoinflammation,immunodeficiency and/or autoimmunity.2022

    • Author(s)
      T. Kaisho.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Immunotherapy of chronic virus infections: exhausted CD8+ T cell subsets are differentially regulated by XCR1+ DC.2022

    • Author(s)
      A.Meyerhans, E.D-Vila, V.Casella, R.Iwabuxhi, E.Fossum, M.Pedragosa, Q.Castellvi, T.Kaisho, K.Terahara, G.Bocharov, J.Argilaguet.
    • Organizer
      The 16th International Symposium on Dendritic Cells 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] γδT17 cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation by commensals.2022

    • Author(s)
      S. Komiyama, D. Takahashi, T. Kaisho, H. Watarai, K. Hase.
    • Organizer
      The 9th Congress of International Human Microbiome Consortium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Model mice of human inborn errors of immunity showing mixed manifestations of aouoinflammation,immunodeficiency and/or autoimmunity.2022

    • Author(s)
      T. Kaisho
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Hypomorphic mutation of Lig4 gene in mice predisposes to intestinal inflammation driven by Th1 cells2022

    • Author(s)
      Y. Yamashita, T. Kato, H. Kosako, S. Iwabuchi, K. Tanaka, K. Nakashima, I. Sasaki, S. Hashimoto, K. Ohshima, T. Kaisho, T. Sonoki, S. Tamura.
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] Activation of type 1 interferon signaling in dendritic cells and T cells of the mouse model of COPA syndrome.2022

    • Author(s)
      T.Kato, R.Yamasaki, N.W-Nishiyama. I.Sasaki, S.Kaji, K.Murakami, H.Hemmi, Y.Honda, K.Izawa, Y.Otsuki, T.Matsubayashi, R.Nishikomori, T.Kaisho.
    • Organizer
      第29回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Dendritic and T cell abnormalities in an autoinflammatory disease with interstitial lung disease and type 1 interferonopathy caused by a disability of retrongrade protein trafficking.2022

    • Author(s)
      T. Kato, I.Sasaki, H. Hemmi, Y. Honda. K. Izawa, R. Nishikomori, T. Kaisho.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Lig4遺伝子の低形成性変異を有したマウスは異常Th1細胞による炎症性腸疾患を発症する2022

    • Author(s)
      田村志宜、山下友佑、小浴秀樹、加藤喬、岩淵貞弘、佐々木泉、橋本真一、改正恒康
    • Organizer
      第6回日本免疫不全・自己炎症学会総会
    • Data Source
      KAKENHI-PLANNED-22H05187
  • [Presentation] γδT17 cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation by commensals.2022

    • Author(s)
      S. Komiyama, D. Takahashi, T. Kaisho, H. Watarai, K. Hase.
    • Organizer
      The 9th Congress of International Human Microbiome Consortium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Immunotherapy of chronic virus infections: exhausted CD8+ T cell subsets are differentially regulated by XCR1+ DC.2022

    • Author(s)
      A.Meyerhans, E.D-Vila, V.Casella, R.Iwabuxhi, E.Fossum, M.Pedragosa, Q.Castellvi, T.Kaisho, K.Terahara, G.Bocharov, J.Argilaguet.
    • Organizer
      The 16th International Symposium on Dendritic Cells 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Immunotherapy of chronic virus infections: exhausted CD8+ T cell subsets are differentially regulated by XCR1+ DC.2022

    • Author(s)
      A.Meyerhans, E.D-Vila, V.Casella, R.Iwabuxhi, E.Fossum, M.Pedragosa, Q.Castellvi, T.Kaisho, K.Terahara, G.Bocharov, J.Argilaguet.
    • Organizer
      The 16th International Symposium on Dendritic Cells 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Type 1 conventional dendritic cells of bone marrow assistthe prograession of multiple myeloma and consist of tumor microenvironment in the transplanted Vk*MYC mouse model.2022

    • Author(s)
      S.Suzuki, S.Tsuda, T.Takubo, H.Toyoshima, M.Yoshino, T.Kaisho, T.Fukuda, K.Tokoyoda.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Model mice of human inborn errors of immunity showing mixed manifestations of aouoinflammation,immunodeficiency and/or autoimmunity.2022

    • Author(s)
      T. Kaisho.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] γδT17 cells in Peyer’s patches acquire the encephalitogenic phenotype through the activation by commensals.2022

    • Author(s)
      S. Komiyama, D. Takahashi, T. Kaisho, H. Watarai, K. Hase.
    • Organizer
      The 9th Congress of International Human Microbiome Consortium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Dendritic and T cell abnormalities in an autoinflammatory disease with interstitial lung disease and type 1 interferonopathy caused by a disability of retrongrade protein trafficking.2022

    • Author(s)
      T. Kato, I.Sasaki, H. Hemmi, Y. Honda. K. Izawa, R. Nishikomori, T. Kaisho.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Hypomorphic mutation of Lig4 gene in mice predisposes to intestinal inflammation driven by Th1 cells.2022

    • Author(s)
      Y. Yamashita, T. Kato, H. Kosako, S. Iwabuchi, K. Tanaka, K. Nakashima, I. Sasaki, S. Hashimoto, K. Ohshima, T. Kaisho, T. Sonoki, S. Tamura.
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Activation of type 1 interferon signaling in dendritic cells and T cells of the mouse model of COPA syndrome.2022

    • Author(s)
      T.Kato, R.Yamasaki, N.W-Nishiyama. I.Sasaki, S.Kaji, K.Murakami, H.Hemmi, Y.Honda, K.Izawa, Y.Otsuki, T.Matsubayashi, R.Nishikomori, T.Kaisho.
    • Organizer
      第29回日本免疫毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Lig4遺伝子の低形成性変異を有したマウスは異常Th1細胞による炎症性腸疾患を発症する2022

    • Author(s)
      田村志宜、山下友佑、小浴秀樹、加藤喬、岩淵貞弘、佐々木泉、橋本真一、改正恒康
    • Organizer
      第6回日本免疫不全・自己炎症学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Lig4遺伝子の低形成性変異を有したマウスは異常Th1細胞による炎症性腸疾患を発症する2022

    • Author(s)
      田村志宜、山下友佑、小浴秀樹、加藤喬、岩淵貞弘、佐々木泉、橋本真一、改正恒康
    • Organizer
      第6回日本免疫不全・自己炎症学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Hypomorphic mutation of Lig4 gene in mice predisposes to intestinal inflammation driven by Th1 cells2022

    • Author(s)
      Y. Yamashita, T. Kato, H. Kosako, S. Iwabuchi, K. Tanaka, K. Nakashima, I. Sasaki, S. Hashimoto, K. Ohshima, T. Kaisho, T. Sonoki, S. Tamura.
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] The role of Rnase T2 in macrophage homeostasis.2022

    • Author(s)
      R. Sato, K.Liu, T.Shibata, R.Fukui, K.Hoshino, T.Kaisho, K.Miyake.
    • Organizer
      第51回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 自己炎症性疾患COPA症候群モデルマウスにおけるI型IFN症発症の分子基盤2021

    • Author(s)
      加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、村上康平、邊見弘明、本田吉孝、井澤和司、大月寛郎、松林正、西小森隆太、改正恒康
    • Organizer
      第28回日本免疫毒性学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Chemokine-medicated delivery of cancer peptide vaccine to a dendritic cell subset with high crosspresentation activity2021

    • Author(s)
      Y. Mizumoto, H. Hemmi, M. Katsuda, Y. Fukuda-Ohta, T. Orimo, I. Sasaki, K. Tamada, H. Yamaue, T. Kaisho
    • Organizer
      The 27th International Symposium on Molecular Cell Biology of Macrophage (MMCB 2020+1)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] XCR1陽性樹状細胞分化におけるプロテアソームの役割2021

    • Author(s)
      西山奈央子、佐々木泉、邊見弘明、改正恒康
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 樹状細胞サブセット(XCRl+DC)への特異的送達によるがんペプチドワクチン療法2021

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、松田健司、尾島敏康、邊見弘明、玉田耕治、改正恒康、山上裕機
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Hyperactivation of STING-induced type I interferon pathway in dendritic cells from novel mice model for an autoinflammatory disease, COPA syndrome2021

    • Author(s)
      T. Kato, T. Orimo, Y. Fukuda-Ohta, I. Sasaki, H. Hemmi, Y. Honda, K. Izawa, R. Nishikomori, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] An endoplasmic reticulum stress sensor IRE1α is involved in cholera toxin-induced interleukin-1β production from tissue resident macrophages2021

    • Author(s)
      I. Sasaki, Y. Fukuda-Ohta, N. Wakaki-Nishiyama, C. Nakai, S. Morita, D. Okuzaki, M. Kaku, K. Sawase, T. Kato, T. Orimo, K. Furukawa, T. Kaisho
    • Organizer
      第28回日本免疫毒性学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Critical roles of IRE1α in cholera toxin-induced interleukin-1β production from resident peritoneal macrophages2021

    • Author(s)
      I. Sasaki, Y. Fukuda-Ohta, N. Wakaki-Nishiyama, C. Nakai, S. Morita, D. Okuzaki, M. Kaku, K. Sawase, A. Yamamoto, T. Kato, T. Orimo, K. Furukawa, T. Kaisho
    • Organizer
      IEIIS2021: 16th Meeting of the International Endotoxin and Innate Immunity Society (26tth Japanese Endotoxin and innate Immunity Society)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] コレラ毒素による炎症性サイトカインIL-6産生誘導機構の解明2021

    • Author(s)
      賀来美嘉、加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第89回和歌山医学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] XCR1+DCをターゲットにした whole-cell-vaccineの開発2021

    • Author(s)
      宮本篤、勝田将裕、宮澤基樹、北畑裕司、水本有紀、小林良平、尾島敏康、邊見弘明、戸村道夫、改正恒康、山上裕機
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Unique location in the immunoproteasome complex of a variant causing proteasome-associated autoinflammatory syndrome with immunodeficiency2021

    • Author(s)
      N. Kanazawa, H. Hemmi, N. Kinjo, H. Ohnishi, J. Hamazaki, H. Mishima, A. Kinoshita, T. Mizushima, S. Murata, K. Yoshiura, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] コレラ毒素Bサブユニットによる免疫アジュバント活性における小胞体ストレスセンサーIRE1αの機能的意義2021

    • Author(s)
      佐々木泉, 改正恒康
    • Organizer
      第34回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] XCR1陽性樹状細胞分化におけるプロテアソームの役割2021

    • Author(s)
      西山奈央子、佐々木泉、邊見弘明、改正恒康
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] コレラ毒素による免疫アジュバント活性における小胞体ストレスセンサーIRE1αの機能的意義2021

    • Author(s)
      佐々木泉、中井千尋、大田有里、西山奈央子、森田修平、奥崎大介、三並桃佳、林茉里、張江伊水、田中日向子、加藤喬、折茂貴是、古川鋼一、改正恒康
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 自己炎症性疾患COPA症候群変異マウスにおけるSTINGシグナルの活性化2021

    • Author(s)
      加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、張江伊水、田中日向子、佐々木泉、村上康平、邊見弘明、本田吉孝、井澤和司、西小森隆太、改正恒康
    • Organizer
      第85回日本インターフェロン・サイトカイン学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Interstitial Lung Disease and abnormal STING activation in COPA V242G heterozygous variant mice2021

    • Author(s)
      T. Kato, T. Orimo, Y. Fukuda-Ohta, N. Wakaki-Nishiyama, C. Nakai, I. Sasaki, K. Murakami, H. Hemmi, Y. Honda, K. Izawa, Y. Otsuki, T. Matsubayashi, R. Nishikomori, T. Kaisho
    • Organizer
      IEIIS2021: 16th Meeting of the International Endotoxin and Innate Immunity Society (26tth Japanese Endotoxin and innate Immunity Society)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] The role of RNase T2 in macrophage homeostasis2021

    • Author(s)
      R. Sato, K. Liu, T. Shibata, K. Miyake, R. Fukui, K. Hoshino, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Activation of γδT Cells by Commensals Exacerbates Autoimmune Encephalomyelitis2021

    • Author(s)
      S. Komiyama, D. Takahashi, A. Saeki, T. Kaisho
    • Organizer
      The 8th Federation of Immunological Societies of Asia-Oceania
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Analysis of innate immune cells in proteasome subunit mutant mice2021

    • Author(s)
      H. Hemmi, T. Orimo, I. Sasaki, T. Kato, Y. Fukuda-Ohta, N. Kinjo, H. Ohnishi, N. Kanzawa, T. Kaisho
    • Organizer
      IEIIS2021: 16th Meeting of the International Endotoxin and Innate Immunity Society (26tth Japanese Endotoxin and innate Immunity Society)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Impaired development of myeloid cells in proteasome subunit mutant mice2021

    • Author(s)
      H. Hemmi, T. Orimo, I. Sasaki, T. Kato, Y. Fukuda-Ohta, N. Kinjo, H. Ohnishi, N. Kanazawa, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Th1-skewing colitis in mutant mice with homozygous missense mutation of DNA ligase IV2021

    • Author(s)
      S. Tamura, Y. Yamashita, T. Orimo, S. Iwabuchi, I. Sasaki, H. Hemmi, S. Hashimoto, T. Sonoki, T. Kaisho
    • Organizer
      The 27th International Symposium on Molecular Cell Biology of Macrophage (MMCB 2020+1)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 自己炎症性疾患COPA症候群変異マウスにおけるSTINGシグナルの活性化2021

    • Author(s)
      加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、張江伊水、田中日向子、佐々木泉、村上康平、邊見弘明、本田吉孝、井澤和司、西小森隆太、改正恒康
    • Organizer
      第85回日本インターフェロン・サイトカイン学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] 樹状細胞サブセット(XCRl+DC)への特異的送達によるがんペプチドワクチン療法2021

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、松田健司、尾島敏康、邊見弘明、玉田耕治、改正恒康、山上裕機
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] COPA症候群の新規モデルマウスにおけるSTINGの活性化とT細胞の異常. Activation of STING and T cell abnormalities in a novel mouse model of COPA syndrome2021

    • Author(s)
      加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、村上康平、邊見弘明、本田吉孝、井澤和司、八角高裕、大月寛郎、松林正、西小森隆太、改正恒康
    • Organizer
      第5回日本免疫不全・自己炎症学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Chemokine-medicated delivery of cancer peptide vaccine to a dendritic cell subset with high crosspresentation activity2021

    • Author(s)
      Y. Mizumoto, H. Hemmi, M. Katsuda, Y. Fukuda-Ohta, T. Orimo, I. Sasaki, K. Tamada, H. Yamaue, T. Kaisho
    • Organizer
      The 27th International Symposium on Molecular Cell Biology of Macrophage (MMCB 2020+1)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] 自然免疫応答における小胞体ストレスセンサーIRE1αの機能的意義2021

    • Author(s)
      澤瀬幹太、加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第89回和歌山医学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] がん免疫療法における抗原提示細胞の意義2021

    • Author(s)
      改正恒康
    • Organizer
      第25回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] An endoplasmic reticulum stress sensor IRE1α is involved in cholera toxin-induced interleukin-1β production from resident peritoneal macrophages2021

    • Author(s)
      I. Sasaki, Y. Fukuda-Ohta, S. Morita, D. Okuzaki, T. Kato, T. Orimo, K. Furukawa, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Analysis of innate immune cells in proteasome subunit mutant mice2021

    • Author(s)
      H. Hemmi, T. Orimo, I. Sasaki, T. Kato, Y. Fukuda-Ohta, N. Kinjo, H. Ohnishi, N. Kanzawa, T. Kaisho
    • Organizer
      IEIIS2021: 16th Meeting of the International Endotoxin and Innate Immunity Society (26tth Japanese Endotoxin and innate Immunity Society)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] 自己炎症性疾患COPA症候群モデルマウスにおけるI型IFN症発症の分子基盤2021

    • Author(s)
      加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、村上康平、邊見弘明、本田吉孝、井澤和司、大月寛郎、松林正、西小森隆太、改正恒康
    • Organizer
      第28回日本免疫毒性学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Spi-B plays a protective role in pressure overload-induced heart failure through the proliferation of resident macrophages2021

    • Author(s)
      A. Kimura, Y. Ishida, M. Nosaka, Y. Kuninaka, A. Taruya, I. Sasaki, T. Kaisho, Toshikazu Kondo
    • Organizer
      The 27th International Symposium on Molecular Cell Biology of Macrophage (MMCB 2020+1)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 遺伝子改変マウスを用いたCOPA症候群の病態解明2021

    • Author(s)
      加藤喬、川野果歩、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第89回和歌山医学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Hypomorphic mutation of Lig4 gene in mice predisposes to intestinal inflammation driven by CD4+ Th1 cells2021

    • Author(s)
      Y. Yamashita, T. Orimo, T. Kato, Y. Fukuda-Ohta, I. Sasaki, H. Hemmi, S. Tamura, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Sublingual dendritic cell (DC) - T cell clusters and distribution of DCs in the oral cavity2021

    • Author(s)
      Y. Kusumoto, T. Kaisho, H. Hemmi, T. Katakai, T. Honda, J. Kikuta, K. Kataoka, T. Moriya, M. Ishii, K. Kabashima, M. Tomura
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Sublingual dendritic cell (DC) - T cell clusters and distribution of DCs in the oral cavity2021

    • Author(s)
      Y. Kusumoto, T. Kaisho, H. Hemmi, T. Katakai, T. Honda, J. Kikuta, K. Kataoka, T. Moriya, M. Ishii, K. Kabashima, M. Tomura
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 遺伝子改変マウスを用いたCOPA症候群の病態解明2021

    • Author(s)
      加藤喬、川野果歩、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第89回和歌山医学会総会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] XCR1+DCをターゲットにした whole-cell-vaccineの開発2021

    • Author(s)
      宮本篤、勝田将裕、宮澤基樹、北畑裕司、水本有紀、小林良平、尾島敏康、邊見弘明、戸村道夫、改正恒康、山上裕機
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Interstitial Lung Disease and abnormal STING activation in COPA V242G heterozygous variant mice2021

    • Author(s)
      T. Kato, T. Orimo, Y. Fukuda-Ohta, N. Wakaki-Nishiyama, C. Nakai, I. Sasaki, K. Murakami, H. Hemmi, Y. Honda, K. Izawa, Y. Otsuki, T. Matsubayashi, R. Nishikomori, T. Kaisho
    • Organizer
      IEIIS2021: 16th Meeting of the International Endotoxin and Innate Immunity Society (26tth Japanese Endotoxin and innate Immunity Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 腸管におけるIL-17産生性γδT細胞の活性化と実験的自己免疫性脳脊髄炎への関与2021

    • Author(s)
      込山星河、髙橋大輔、佐伯愛子、改正恒康、長谷耕二
    • Organizer
      第33回日本神経免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] COPA症候群の新規モデルマウスにおけるSTINGの活性化とT細胞の異常. Activation of STING and T cell abnormalities in a novel mouse model of COPA syndrome2021

    • Author(s)
      加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、村上康平、邊見弘明、本田吉孝、井澤和司、八角高裕、大月寛郎、松林正、西小森隆太、改正恒康
    • Organizer
      第5回日本免疫不全・自己炎症学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Impaired monocyte and dendritic cell development in mice carrying a mutation identified from the proteasome-associated autoinflammation and immunodeficiency disease patient.2021

    • Author(s)
      H. Hemmi, T. Orimo, Naoko Nishiyama, T. Kato, T. Ozasa, I. Sasaki, H. Ohnishi, N. Kinjo, N. Kanzawa, T. Kaisho
    • Organizer
      The 27th International Symposium on Molecular Cell Biology of Macrophage (MMCB 2020+1)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] 腸内細菌による腸管γδT細胞の活性化と自己免疫性脳脊髄炎への寄与2021

    • Author(s)
      込山星河、髙橋大輔、佐伯愛子、改正恒康、長谷耕二
    • Organizer
      薬学会フォーラム
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Unique location in the immunoproteasome complex of a variant causing proteasome-associated autoinflammatory syndrome with immunodeficiency2021

    • Author(s)
      N. Kanazawa, H. Hemmi, N. Kinjo, H. Ohnishi, J. Hamazaki, H. Mishima, A. Kinoshita, T. Mizushima, S. Murata, K. Yoshiura, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Impaired development of myeloid cells in proteasome subunit mutant mice2021

    • Author(s)
      H. Hemmi, T. Orimo, I. Sasaki, T. Kato, Y. Fukuda-Ohta, N. Kinjo, H. Ohnishi, N. Kanazawa, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Impaired monocyte and dendritic cell development in mice carrying a mutation identified from the proteasome-associated autoinflammation and immunodeficiency disease patient2021

    • Author(s)
      H. Hemmi, T. Orimo, Naoko Nishiyama, T. Kato, T. Ozasa, I. Sasaki, H. Ohnishi, N. Kinjo, N. Kanzawa, T. Kaisho
    • Organizer
      The 27th International Symposium on Molecular Cell Biology of Macrophage (MMCB 2020+1)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Hyperactivation of STING-induced type I interferon pathway in dendritic cells from novel mice model for an autoinflammatory disease, COPA syndrome2021

    • Author(s)
      T. Kato, T. Orimo, Y. Fukuda-Ohta, I. Sasaki, H. Hemmi, Y. Honda, K. Izawa, R. Nishikomori, T. Kaisho
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] コレラ毒素Bサブユニットによる炎症性サイトカインIL-1βの産生誘導機構2021

    • Author(s)
      大田有里、佐々木泉、古川鋼一、改正恒康
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] がん免疫療法における抗原提示細胞の意義2021

    • Author(s)
      改正恒康
    • Organizer
      第25回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19384
  • [Presentation] Role of cross-presenting dendritic cells in anti-PD-L1 immunotherapy of chronic viral infections.2020

    • Author(s)
      E. Domenjo-Vila, V. Casella, R. Iwabuchi, E. Fossum, M. Pedragosa, Q. Castellvi, T. Kaisho, K. Terahara, G. Bocharov, J. Argilaguet, A. Meyerhans.
    • Organizer
      2nd Research Symposium on Coronavirus / XIX Jornada de Virologia / Virology Meeting 2020. Online meeting.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] Role of cross-presenting dendritic cells in anti-PD-L1 immunotherapy of chronic viral infections.2020

    • Author(s)
      E. Domenjo-Vila, V. Casella, R. Iwabuchi, E. Fossum, M. Pedragosa, Q. Castellvi, T. Kaisho, K. Terahara, G. Bocharov, J. Argilaguet, A. Meyerhans.
    • Organizer
      2nd Research Symposium on Coronavirus / XIX Jornada de Virologia / Virology Meeting 2020. Online meeting.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] 遺伝性炎症性疾患COPA症候群のモデルマウスの樹立とその解析2020

    • Author(s)
      張江伊水、滝沢優子、加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第88回和歌山医学会総会(WEB開催)
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Impaired development of myeloid cells in mice carrying a patient-derived proteasome subunit mutation.2020

    • Author(s)
      邊見弘明、折茂貴是、佐々木泉、加藤喬、大田(福田)有里、金城紀子、濱田聡、木下晃、吉浦孝一郎、大西秀典、金澤伸雄、改正恒康
    • Organizer
      第3回日本免疫不全・自己炎症学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] The roles of unfold protein responses in cholera toxinB-induced interleukin-1β production.2020

    • Author(s)
      佐々木泉、折茂貴是、張江伊水、滝沢優子、古川綱一、改正恒康
    • Organizer
      第27回日本免疫毒性学会学術年会(WEB開催)
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] 自然免疫応答における小胞体ストレスセンサ ー IREla の機能的意義2020

    • Author(s)
      三並桃花、石田エヴァ如月、加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第88回和歌山医学会総会(WEB開催)
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 遺伝性炎症性疾患COPA症候群の分子基盤の解明2020

    • Author(s)
      田中日尚子、林茉里、加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第88回和歌山医学会総会(WEB開催)
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 遺伝性炎症性疾患COPA症候群の分子基盤の解明2020

    • Author(s)
      田中日尚子、林茉里、加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第88回和歌山医学会総会(WEB開催)
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Impaired development of myeloid cells in mice carrying a patient-derived proteasome subunit mutation.2020

    • Author(s)
      邊見弘明、折茂貴是、佐々木泉、加藤喬、大田(福田)有里、金城紀子、濱田聡、木下晃、吉浦孝一郎、大西秀典、金澤伸雄、改正恒康
    • Organizer
      第3回日本免疫不全・自己炎症学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 自然免疫応答における小胞体ストレスセンサ ー IREla の機能的意義2020

    • Author(s)
      三並桃花、石田エヴァ如月、加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第88回和歌山医学会総会(WEB開催)
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] The roles of unfold protein responses in cholera toxinB-induced interleukin-1β production.2020

    • Author(s)
      佐々木泉、折茂貴是、張江伊水、滝沢優子、古川綱一、改正恒康
    • Organizer
      第27回日本免疫毒性学会学術年会(WEB開催)
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] 遺伝性炎症性疾患COPA症候群のモデルマウスの樹立とその解析2020

    • Author(s)
      張江伊水、滝沢優子、加藤喬、折茂貴是、大田(福田)有里、西山奈央子、中井千尋、佐々木泉、改正恒康
    • Organizer
      第88回和歌山医学会総会(WEB開催)
    • Data Source
      KAKENHI-PROJECT-20H03505
  • [Presentation] ヒト疾患由来プロテアソームサブユニット突然変異導入マウスにおける樹状細胞分化障害2019

    • Author(s)
      邊見弘明、小笹俊哉、加藤喬、折茂貴是、大田(福田)有里、金澤伸雄、改正恒康
    • Organizer
      第29回日本樹状細胞研究会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Generation and analysis of mice carrying a novel heterozygous missense mutation of a protease subunit, PSMB9, in patients with autoinflammation and immunodeficiency.2019

    • Author(s)
      H. Hemmi, N. Kanazawa, N. Kinjo, S. Hamada, H. Ohnishi, T. Mizushima, A. Kinoshita, K.-I. Yoshiura, T. Kaisho.
    • Organizer
      The 10th Biannual Meeting of the International Society of Systemic Auto-Inflammatory Diseases (ISSAID)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Lig4遺伝子改変マウスを用いた腸管免疫寛容破綻の病態解明2019

    • Author(s)
      田村志宣、山下友佑、折茂貴是、大田(福田)有里、小笹俊哉、中嶋一貴、金澤伸雄、邊見弘明、大島孝一、改正恒康、園木孝志
    • Organizer
      第47回日本臨床免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Sox8 is essential for the maturation of M cells and accelerates IgA response at the early stage after weaning.2019

    • Author(s)
      N. Kobayashi, S. Kimura, Y. Nakamura, T. Kanaya, T. Kaisho, H. Ohno, T. Iwanaga, K. Hase
    • Organizer
      The 18th Awaji International Forum on Infection and Immunity.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Novel proteasome-related autoinflammation and immunodeficiency disease caused by a distinct heterozygous missense mutation in the PSMB9 gene.2019

    • Author(s)
      N. Kanazawa, Y. Nakatani, Y. Inaba, K. Kunimoto, N. Kinjo, S. Hamada, T. Mizushima, A. Kinoshita, K. Yoshiura, J. Hamazaki, S. Murata, H. Ohnishi, T. Orimo, H. Hemmi, T. Kaisho.
    • Organizer
      The 44th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Novel proteasome-related autoinflammation and immunodeficiency disease caused by a distinct heterozygous missense mutation in the PSMB9 gene.2019

    • Author(s)
      N. Kanazawa, N. Kinjo, S. Hamada, T. Mizushima, A. Kinoshita, K. Yoshiura, J. Hamazaki, S. Murata, H. Ohnishi, T. Orimo, H. Hemmi, T. Kaisho.
    • Organizer
      第48回日本免疫学会総会・学術集会記録
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Regulatory T cells with a distinctive feature expand through dermal dendritic cells in the ultraviolet B exposed skin.2019

    • Author(s)
      S. Yamazaki, M. Odanaka, H. Shime, M. Imai, H. Hemmi, T. Kaisho, N. Ohkura, S. Sakaguchi, A. Morita.
    • Organizer
      16th International Workshop on Langerhans Cells
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] 乳児期から発熱と凍瘡様皮疹を反復し、新規のインターフェロン調節遺伝子異常が疑われた親子例2019

    • Author(s)
      本田尭、土橋隆俊、番場正博、大方詩子、渡辺絵美子、宮川俊一、杉浦仁、稲葉豊、神人正寿、井澤和司、邊見弘明、改正恒康、三嶋博之、木下晃、吉浦孝一郎、金澤伸雄
    • Organizer
      第2回日本免疫不全・自己炎症学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 乳児期から発熱と凍瘡様皮疹を反復し、新規のインターフェロン調節遺伝子異常が疑われた親子例2019

    • Author(s)
      本田尭、土橋隆俊、番場正博、大方詩子、渡辺絵美子、宮川俊一、杉浦仁、稲葉豊、神人正寿、井澤和司、邊見弘明、改正恒康、三嶋博之、木下晃、吉浦孝一郎、金澤伸雄
    • Organizer
      第2回日本免疫不全・自己炎症学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Novel proteasome-related autoinflammation and immunodeficiency disease caused by a distinct heterozygous missense mutation in the PSMB9 gene.2019

    • Author(s)
      N. Kanazawa, Y. Nakatani, Y. Inaba, K. Kunimoto, N. Kinjo, S. Hamada, T. Mizushima, A. Kinoshita, K. Yoshiura, J. Hamazaki, S. Murata, H. Ohnishi, T. Orimo, H. Hemmi, T. Kaisho
    • Organizer
      The 44th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 複合免疫不全症を来す新規LIG4症候群モデルマウスは炎症性腸疾患を自然発症する2019

    • Author(s)
      田村志宣、山下友佑、大田(福田)有里、小笹俊哉、金澤伸雄、安岡弘直, 邊見弘明, 大島孝一、改正恒康、園木孝志
    • Organizer
      第59回リンパ網内系学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Analysis of mice carrying a novel mutation in a proteasome subunit gene identifed in an autoinammatory disease patient2019

    • Author(s)
      金澤伸雄、小笹俊哉、邊見弘明、加藤喬、折茂貴是、佐々木泉、福田(大田)有里、改正恒康、木下晃、吉浦孝一郎、金城紀子、水島恒裕
    • Organizer
      第2回日本免疫不全・自己炎症学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Analysis of mice carrying a novel mutation in a proteasome subunit gene identifed in an autoinammatory disease patient2019

    • Author(s)
      金澤伸雄、小笹俊哉、邊見弘明、加藤喬、折茂貴是、佐々木泉、福田(大田)有里、改正恒康、木下晃、吉浦孝一郎、金城紀子、水島恒裕
    • Organizer
      第2回日本免疫不全・自己炎症学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Roles of endoplasmic reticulum stress in cholera toxinB-induced interleukine-1β production from resident peritoneal macrophages.2019

    • Author(s)
      I. Sasaki, S. Morita, D. Okuzaki, T. Orimo, H. Hemmi, K. Furukawa, T. Kaisho.
    • Organizer
      第48回日本免疫学会総会・学術集会記録
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Generation and analysis of mice carrying a novel heterozygous missense mutation of a protease subunit, PSMB9, in patients with autoinflammation and immunodeficiency.2019

    • Author(s)
      H. Hemmi, N. Kanazawa, N. Kinjo, S. Hamada, H. Ohnishi, T. Mizushima, A. Kinoshita, K.-I. Yoshiura, T. Kaisho.
    • Organizer
      The 10th Biannual Meeting of the International Society of Systemic Auto-Inflammatory Diseases (ISSAID).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 実験的自己免疫性脳脊髄炎の病態形成における腸管免疫系の重要性の検証2019

    • Author(s)
      込山星河、江川愛子、高橋大輔、改正恒康、長谷耕二
    • Organizer
      日本薬学会関東支部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] ヒト疾患由来プロテアソームサブユニット突然変異導入マウスにおける樹状細胞分化障害2019

    • Author(s)
      邊見弘明、小笹俊哉、加藤喬、折茂貴是、大田(福田)有里、金澤伸雄、改正恒康
    • Organizer
      第29回日本樹状細胞研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] コレラ毒素Bサブユニットによる炎症性サイトカインIL-1β産生誘導機構2019

    • Author(s)
      佐々木泉、折茂貴是、邊見弘明、土屋慧馬、井上正一、熊谷直光、古川鋼一、改正恒康
    • Organizer
      第26回日本免疫毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Defective dendritic cell and monocyte development in proteasome subunit mutant miceDefective dendritic cell and monocyte development in proteasome subunit mutant mice.2019

    • Author(s)
      H. Hemmi, T. Orimo, I. Sasaki, T. Kato, Y. Fukuda-Ohta, N. Kinjo, S. Hamada, A. Kinoshita, K. Yoshiura, H. Ohnishi, N. Kanazawa, T. Kaisho.
    • Organizer
      第48回日本免疫学会総会・学術集会記録
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Cholera toxin B can induce interleukine-1β production from resident peritoneal macrophages in synergy with lipopolysaccharides.2019

    • Author(s)
      I. Sasaki, T. Orimo, H. Hemmi, K. Furukawa, T. Kaisho.
    • Organizer
      The 18th Awaji International Forum on Infection and Immunity.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Analysis of mice carrying a novel mutation in a proteasome subunit gene identifed in an autoinammatory disease patient2019

    • Author(s)
      金澤伸雄、小笹俊哉、邊見弘明、加藤喬、折茂貴是、佐々木泉、福田(大田)有里、改正恒康、木下晃、吉浦孝一郎、金城紀子、水島恒裕
    • Organizer
      第2回日本免疫不全・自己炎症学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] A case of neonatal-onset proteasome-associated autoinflammation and immunodeficiency disease resembling but distinct from Nakajo-Nishimura syndrome.2019

    • Author(s)
      Kinjo, S. Hamads, K. Nakanishi, H. Mishima, A. Kinoshita, K.-I. Yoshiura, T. Mizushima, J. Hamazaki, S. Murata, H. Hemmi, T. Kaisho, N. Kanazawa.
    • Organizer
      The 10th Biannual Meeting of the International Society of Systemic Auto-Inflammatory Diseases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Defective dendritic cell and monocyte development in proteasome subunit mutant miceDefective dendritic cell and monocyte development in proteasome subunit mutant mice.2019

    • Author(s)
      H. Hemmi, T. Orimo, I. Sasaki, T. Kato, Y. Fukuda-Ohta, N. Kinjo, S. Hamada, A. Kinoshita, K. Yoshiura, H. Ohnishi, N. Kanazawa, T. Kaisho.
    • Organizer
      第48回日本免疫学会総会・学術集会記録
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Lig4遺伝子改変マウスを用いた腸管免疫寛容破綻の病態解明2019

    • Author(s)
      田村志宣、山下友佑、折茂貴是、大田(福田)有里、小笹俊哉、中嶋一貴、金澤伸雄、邊見弘明、大島孝一、改正恒康、園木孝志
    • Organizer
      第47回日本臨床免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Roles of endoplasmic reticulum stress in cholera toxinB-induced interleukine-1β production from resident peritoneal macrophages.2019

    • Author(s)
      I. Sasaki, S. Morita, D. Okuzaki, T. Orimo, H. Hemmi, K. Furukawa, T. Kaisho.
    • Organizer
      第48回日本免疫学会総会・学術集会記録
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Cholera toxin B can induce interleukine-1β production from resident peritoneal macrophages in synergy with lipopolysaccharides.2019

    • Author(s)
      I. Sasaki, T. Orimo, H. Hemmi, K. Furukawa, T. Kaisho.
    • Organizer
      The 18th Awaji International Forum on Infection and Immunity.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Akimichi Morita, Sayuri Yamazaki.Successful treatment of psoriatic inflammation improves hyperglycemia in humans and mice.2019

    • Author(s)
      M. Odanaka, K. Ikumi, H. Shime, M. Imai, E. Nishida, H. Hemmi, T. Kaisho.
    • Organizer
      第48回日本免疫学会総会・学術集会記録
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Novel proteasome-related autoinflammation and immunodeficiency disease caused by a distinct heterozygous missense mutation in the PSMB9 gene.2019

    • Author(s)
      N. Kanazawa, N. Kinjo, S. Hamada, T. Mizushima, A. Kinoshita, K. Yoshiura, J. Hamazaki, S. Murata, H. Ohnishi, T. Orimo, H. Hemmi, T. Kaisho.
    • Organizer
      第48回日本免疫学会総会・学術集会記録
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] A case of neonatal-onset proteasome-associated autoinflammation and immunodeficiency disease resembling but distinct from Nakajo-Nishimura syndrome.2019

    • Author(s)
      Kinjo, S. Hamads, K. Nakanishi, H. Mishima, A. Kinoshita, K.-I. Yoshiura, T. Mizushima, J. Hamazaki, S. Murata, H. Hemmi, T. Kaisho, N. Kanazawa.
    • Organizer
      The 10th Biannual Meeting of the International Society of Systemic Auto-Inflammatory Diseases (ISSAID).
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] コレラ毒素Bサブユニットは細胞内病原体センサーNLRP3とPyrinを介して炎症性サイトカインIL-1βの産生を誘導する2019

    • Author(s)
      佐々木泉、折茂貴是、邊見弘明、古川鋼一、改正恒康
    • Organizer
      第29回日本樹状細胞研究会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] コレラ毒素Bサブユニットによる炎症性サイトカインIL-1β産生誘導機構2019

    • Author(s)
      佐々木泉、折茂貴是、邊見弘明、土屋慧馬、井上正一、熊谷直光、古川鋼一、改正恒康
    • Organizer
      第26回日本免疫毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Regulatory T cells with a distinctive feature expand through dermal dendritic cells in the ultraviolet B exposed skin.2019

    • Author(s)
      S. Yamazaki, M. Odanaka, H. Shime, M. Imai, H. Hemmi, T. Kaisho, N. Ohkura, S. Sakaguchi, A. Morita.
    • Organizer
      16th International Workshop on Langerhans Cells
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Sox8 is essential for the maturation of M cells and accelerates IgA response at the early stage after weaning. The 18th Awaji International Forum on Infection and Immunity.2019

    • Author(s)
      N. Kobayashi, S. Kimura, Y. Nakamura, T. Kanaya, T. Kaisho, H. Ohno, T. Iwanaga, K. Hase.
    • Organizer
      Awaji Yumebutai International Conference Center
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] 実験的自己免疫性脳脊髄炎の病態形成における腸管免疫系の重要性の検証2019

    • Author(s)
      込山星河、江川愛子、高橋大輔、改正恒康、長谷耕二
    • Organizer
      日本薬学会関東支部会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Akimichi Morita, Sayuri Yamazaki.Successful treatment of psoriatic inflammation improves hyperglycemia in humans and mice.2019

    • Author(s)
      M. Odanaka, K. Ikumi, H. Shime, M. Imai, E. Nishida, H. Hemmi, T. Kaisho
    • Organizer
      第48回日本免疫学会総会・学術集会記録
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 複合免疫不全症を来す新規LIG4症候群モデルマウスは炎症性腸疾患を自然発症する2019

    • Author(s)
      田村志宣、山下友佑、大田(福田)有里、小笹俊哉、金澤伸雄、安岡弘直, 邊見弘明, 大島孝一、改正恒康、園木孝志
    • Organizer
      第59回リンパ網内系学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] ケモカイン受容体XCR1を発現する樹状細胞サブセットによる免疫制御2019

    • Author(s)
      改正恒康
    • Organizer
      近畿大学薬学部
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] コレラ毒素Bサブユニットは細胞内病原体センサーNLRP3とPyrinを介して炎症性サイトカインIL-1βの産生を誘導する2019

    • Author(s)
      佐々木泉、折茂貴是、邊見弘明、古川鋼一、改正恒康
    • Organizer
      第29回日本樹状細胞研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] ケモカイン受容体XCR1を発現する樹状細胞サブセットによる免疫制御2019

    • Author(s)
      改正恒康.
    • Organizer
      近畿大学薬学部
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04813
  • [Presentation] Immune regulation by a dendritic cell subset expressing a chemokine receptor, XCR12018

    • Author(s)
      Tsuneyasu Kaisho
    • Organizer
      15th International Symposium on Dendritic Cells
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Impaired development of dendritic cells in proteasome subunit mutant mice2018

    • Author(s)
      Hiroaki Hemmi, Toshiya Ozasa, Akira Kinoshita, Takashi Kato, Takashi Orimo, Izumi Sasaki, Yuri Fukuda-Ohta, Noriko Kinjo, Koh-Ichiro Yoshiura, Tsunehiro Mizushima,Nobuo Kanazawa, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Immune regulation by a dendritic cell subset expressing a chemokine receptor, XCR12018

    • Author(s)
      Tsuneyasu Kaisho
    • Organizer
      15th International Symposium on Dendritic Cells
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Cholera toxin B can induce interleukine-1β production in peritoneal macrophages through activation of pyrin inflammasome2018

    • Author(s)
      Izumi Sasaki, Takashi Orimo, Hiroaki Hemmi, Toshiya Ozasa, Yuri Fukuda-Ohta, Mio Morinaka, Shinji Fukuda, Koichi Furukawa, Etsushi Kuroda, Ken J. Ishii, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] 新規LIG4遺伝子変異を導入したLIG4症候群モデルマウス A mouse model of LIG4 syndrome with novel LIG4 mutation2018

    • Author(s)
      山下友佑、田村志宣、福田有里、小笹俊哉、金澤伸雄、邊見弘明、吉浦孝一郎、改正恒康、園木孝志
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] 皮膚科医に知っていただきたい樹状細胞の機能的および病理的意義2018

    • Author(s)
      改正恒康、邊見弘明、小笹俊哉
    • Organizer
      第117回日本日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Cancer Vaccine Composed of Whole Tumor Cells Genetically Modified to Secrete the XCL12018

    • Author(s)
      Atsushi Miyamoto, Hemmi Hiroaki, Yuki Mizumoto, Masahiro Katsuda, Yuri Ohta,Katsuaki Hoshino, Hiroki Yamaue, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] CRISPR/Cas9による腫瘍上のPD-L1欠損はマウス卵巣癌モデルにおいて抗腫瘍免疫を促進し、腫瘍進展を抑制する2018

    • Author(s)
      八幡環、岩橋尚幸、野口智子、溝口美佳、東嶋左緒里、改正恒康、近藤稔和、井篦一彦
    • Organizer
      第46回和歌山悪性腫瘍研究会
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Time-resolved systems analysis of virus infection fate regulation: the XCL1-XCR1 communication axis links T cell exhaustion with effector maintenance2018

    • Author(s)
      J. Argilaguet, M. Pedragosa, A. Esteve-Codina, G. Riera, E. Vidal, C. Peligero-Cruz, D. Andreu, T. Kaisho, G. Bocharov, B. Ludewig, S. Heath, A. Meyerhans
    • Organizer
      15th International Symposium on Dendritic Cells
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Osteoprotegerin-dependent M-cell self-regulation balances gut infection and immunity2018

    • Author(s)
      Shunsuke Kimura, Yutaka Nakamura, Nobuhide Kobayashi, Tsuneyasu Kaisho, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Foxp3+ regulatory T cells are expanded by ultraviolet B-exposed PD-L1+ skin dendritic cell expressing a unique set of genes in a CSF1-independent manner2018

    • Author(s)
      Sayuri Yamazaki, Mizuyu Odanaka, Hiroaki Shime, Masaki Imai, Akiko Nishioka, Saori Kasuya, Dieter Riethmacher, Hiroaki Hemmi, Tsuneyasu Kaisho, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita
    • Organizer
      International Investigative Dermatology 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] A case of neonatal-onset proteasome-associated autoinflammatory syndrome resembling but distinct from Nakajo-Nishimura syndrome2018

    • Author(s)
      Noriko Kinjo, Hiroyuki Mishima, Akira Kinoshita, Koh-Ichiro Yoshiura,Tsunehiro Mizushima, Jun Hamazaki, Shigeo Murata, Hiroaki Hemmi, Tsuneyasu Kaisho,Nobuo Kanazawa
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Foxp3+ regulatory T cells are expanded by ultraviolet B-exposed PD-L1+ skin dendritic cell expressing a unique set of genes in a CSF1-independent manner2018

    • Author(s)
      Sayuri Yamazaki, Mizuyu Odanaka, Hiroaki Shime, Masaki Imai, Akiko Nishioka, Saori Kasuya, Dieter Riethmacher, Hiroaki Hemmi, Tsuneyasu Kaisho, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita
    • Organizer
      International Investigative Dermatology 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] 中條-西村症候群からプロテアソーム関連自己炎症/免疫不全症候群へ2018

    • Author(s)
      金澤伸雄、中谷友美、原知之、稲葉豊、国本佳代、古川福実、神人正寿、金城紀子、水島恒裕、三嶋博之、木下晃、吉浦孝一郎、加藤喬、福田有里、邊見弘明、改正恒康
    • Organizer
      第25回分子皮膚科学フォーラム
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] XCR1+DCへの選択的な送達を目的とした新規抗がんワクチンの開発2018

    • Author(s)
      宮本篤、勝田将裕、邊見弘明、宮澤基樹、北畑裕司、水本有紀、小林良平、改正恒康、山上裕機
    • Organizer
      第46回和歌山悪性腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Cholera toxin B can induce interleukine-1β production in peritoneal macrophages through activation of pyrin inflammasome2018

    • Author(s)
      Izumi Sasaki, Takashi Orimo, Hiroaki Hemmi, Toshiya Ozasa, Yuri Fukuda-Ohta, Mio Morinaka, Shinji Fukuda, Koichi Furukawa, Etsushi Kuroda, Ken J. Ishii, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Dendritic cells expressing a unique set of genes associated with immunological tolerance are specialized to expand thymus-derived Foxp3+ regulatory T cells in the ultraviolet B-exposed skin2018

    • Author(s)
      Sayuri Yamazaki, Mizuyu Odanaka, Akiko Nishioka, Hiroaki Shime, Hiroaki Hemmi,Masaki Imai, Tsuneyasu Kaisho, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections2018

    • Author(s)
      Chikako Shimokawa, Takashi Kanaya, Masami Hachisuka, Kenji Ishiwata, Hajime Hisaeda, Yosuke Kurashima, Hiroshi Kiyono, Tomohiro Yoshimoto, Tsuneyasu Kaisho, Hiroshi Ohno
    • Organizer
      The 3rd International Conference on Innate Lymphoid Cells (ILC2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Hyperglycemia is associated with psoriatic inflammation in both humans and mice2018

    • Author(s)
      Mizuyu Odanaka, Kyoko Ikumi, Hiroaki Shime, Masaki Imai, Hiroaki Hemmi, Tsuneyasu Kaisho, Akimichi Morita, Sayuri Yamazaki
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] プロテアソーム関連自己炎症性症候群のマウスモデル2018

    • Author(s)
      改正恒康、邊見弘明、金澤伸雄、加藤喬、稲葉豊、小笹俊哉
    • Organizer
      第39回日本炎症・再生学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Dendritic cells expressing a unique set of genes associated with immunological tolerance are specialized to expand thymus-derived Foxp3+ regulatory T cells in the ultraviolet B-exposed skin2018

    • Author(s)
      Sayuri Yamazaki, Mizuyu Odanaka, Akiko Nishioka, Hiroaki Shime, Hiroaki Hemmi,Masaki Imai, Tsuneyasu Kaisho, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Analysis of mice carrying a novel mutation in a proteasome subunit gene identified in anautoinflammatory disease patient2018

    • Author(s)
      Toshiya Ozasa, Hiroaki Hemmi, Akira Kinoshita, Takashi Kato, Takashi Orimo, Izumi Sasaki, Yuri Fukuda-Ohta, Noriko Kinjo, Koh-Ichiro Yoshiura, Tsunehiro Mizushima, Nobuo Kanazawa, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Dendritic cells expressing a unique set of genes associated with immunological tolerance are specialized to expand thymus-derived Foxp3+ regulatory T cells in the ultraviolet B-exposed skin2018

    • Author(s)
      Sayuri Yamazaki, Mizuyu Odanaka, Akiko Nishioka, Hiroaki Shime, Hiroaki Hemmi,Masaki Imai, Tsuneyasu Kaisho, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Sox8 is essential for the differentiation of M cells and antigen-specific IgA response2018

    • Author(s)
      Nobuhide Kobayashi, Shunsuke Kimura, Yutaka Nakamura, Takashi Kanaya, Tsuneyasu Kaisho, Hiroshi Ohno, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 中條-西村症候群からプロテアソーム関連自己炎症/免疫不全症候群へ2018

    • Author(s)
      金澤伸雄、中谷友美、原知之、稲葉豊、国本佳代、古川福実、神人正寿、金城紀子、水島恒裕、三嶋博之、木下晃、吉浦孝一郎、加藤喬、福田有里、邊見弘明、改正恒康
    • Organizer
      第25回分子皮膚科学フォーラム
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] CRISPR/Cas9による腫瘍上のPD-L1欠損はマウス卵巣癌モデルにおいて抗腫瘍免疫を促進し、腫瘍進展を抑制する2018

    • Author(s)
      八幡環、岩橋尚幸、野口智子、溝口美佳、東嶋左緒里、改正恒康、近藤稔和、井篦一彦
    • Organizer
      第46回和歌山悪性腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Cancer Vaccine Composed of Whole Tumor Cells Genetically Modified to Secrete the XCL12018

    • Author(s)
      Atsushi Miyamoto, Hemmi Hiroaki, Yuki Mizumoto, Masahiro Katsuda, Yuri Ohta,Katsuaki Hoshino, Hiroki Yamaue, Tsuneyasu Kaisho.
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] M-cell-dependent antigen uptake mitigates infectious colitis by shaping mucosal barrier function2018

    • Author(s)
      Yutaka Nakamura, Hitomi Mimuro, Jun Kunisawa, Tsuneyasu Kaisho, Hiroshi Kiyono, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Sox8 is essential for the differentiation of M cells and antigen-specific IgA response2018

    • Author(s)
      Nobuhide Kobayashi, Shunsuke Kimura, Yutaka Nakamura, Takashi Kanaya, Tsuneyasu Kaisho, Hiroshi Ohno, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Impaired development of dendritic cells in proteasome subunit mutant mice2018

    • Author(s)
      Hiroaki Hemmi, Toshiya Ozasa, Akira Kinoshita, Takashi Kato, Takashi Orimo, Izumi Sasaki, Yuri Fukuda-Ohta, Noriko Kinjo, Koh-Ichiro Yoshiura, Tsunehiro Mizushima,Nobuo Kanazawa, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] CRISPR/Cas9による腫瘍上のPD-L1欠損はマウス卵巣癌モデルにおいて抗腫瘍免疫を促進し、腫瘍進展を抑制する2018

    • Author(s)
      八幡環、岩橋尚幸、野口智子、溝口美佳、東嶋左緒里、改正恒康、近藤稔和、井篦一彦
    • Organizer
      第46回和歌山悪性腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] M-cell-dependent antigen uptake mitigates infectious colitis by shaping mucosal barrier function2018

    • Author(s)
      Yutaka Nakamura, Hitomi Mimuro, Jun Kunisawa, Tsuneyasu Kaisho, Hiroshi Kiyono, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Time-resolved systems analysis of virus infection fate regulation: the XCL1-XCR1 communication axis links T cell exhaustion with effector maintenance2018

    • Author(s)
      J. Argilaguet, M. Pedragosa, A. Esteve-Codina, G. Riera, E. Vidal, C. Peligero-Cruz, D. Andreu, T. Kaisho, G. Bocharov, B. Ludewig, S. Heath, A. Meyerhans
    • Organizer
      15th International Symposium on Dendritic Cells
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] A case of neonatal-onset proteasome-associated autoinflammatory syndrome resembling but distinct from Nakajo-Nishimura syndrome2018

    • Author(s)
      Noriko Kinjo, Hiroyuki Mishima, Akira Kinoshita, Koh-Ichiro Yoshiura,Tsunehiro Mizushima, Jun Hamazaki, Shigeo Murata, Hiroaki Hemmi, Tsuneyasu Kaisho,Nobuo Kanazawa
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Hyperglycemia is associated with psoriatic inflammation in both humans and mice2018

    • Author(s)
      Mizuyu Odanaka, Kyoko Ikumi, Hiroaki Shime, Masaki Imai, Hiroaki Hemmi, Tsuneyasu Kaisho, Akimichi Morita, Sayuri Yamazaki
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] プロテアソーム関連自己炎症性症候群のマウスモデル2018

    • Author(s)
      改正恒康、邊見弘明、金澤伸雄、加藤喬、稲葉豊、小笹俊哉
    • Organizer
      第39回日本炎症・再生学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Successful treatment of psoriatic inflammation restores hyperglycemia2018

    • Author(s)
      Kyoko Ikumi, Mizuyu Odanaka, Hiroaki Shime, Masaki Imai, Osamu Taguchi, Hiroaki Hemmi, Tsuneyasu Kaisho, Sayuri Yamazaki, Akimichi Morita
    • Organizer
      International Investigative Dermatology 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] M-cell-dependent antigen uptake mitigates infectious colitis by shaping mucosal barrier function2018

    • Author(s)
      Yutaka Nakamura, Hitomi Mimuro, Jun Kunisawa, Tsuneyasu Kaisho, Hiroshi Kiyono, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] プロテアソーム関連自己炎症性症候群のマウスモデル2018

    • Author(s)
      改正恒康、邊見弘明、金澤伸雄、加藤喬、稲葉豊、小笹俊哉
    • Organizer
      第39回日本炎症・再生学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Hyperglycemia is associated with psoriatic inflammation in both humans and mice2018

    • Author(s)
      Mizuyu Odanaka, Kyoko Ikumi, Hiroaki Shime, Masaki Imai, Hiroaki Hemmi, Tsuneyasu Kaisho, Akimichi Morita, Sayuri Yamazaki
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections2018

    • Author(s)
      Chikako Shimokawa, Takashi Kanaya, Masami Hachisuka, Kenji Ishiwata, Hajime Hisaeda, Yosuke Kurashima, Hiroshi Kiyono, Tomohiro Yoshimoto, Tsuneyasu Kaisho, Hiroshi Ohno
    • Organizer
      The 3rd International Conference on Innate Lymphoid Cells (ILC2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections2018

    • Author(s)
      Chikako Shimokawa, Takashi Kanaya, Masami Hachisuka, Kenji Ishiwata, Hajime Hisaeda, Yosuke Kurashima, Hiroshi Kiyono, Tomohiro Yoshimoto, Tsuneyasu Kaisho, Hiroshi Ohno
    • Organizer
      The 3rd International Conference on Innate Lymphoid Cells (ILC2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] The mechanism of action of Spi-B in transcriptional activation of the interferon-α4 gene2018

    • Author(s)
      Ryo Miyazaki, Hiroyuki Saiga, Tsuneyasu Kaisho, Katsuaki Hoshino
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Successful treatment of psoriatic inflammation restores hyperglycemia2018

    • Author(s)
      Kyoko Ikumi, Mizuyu Odanaka, Hiroaki Shime, Masaki Imai, Osamu Taguchi, Hiroaki Hemmi, Tsuneyasu Kaisho, Sayuri Yamazaki, Akimichi Morita
    • Organizer
      International Investigative Dermatology 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Immune regulation by a dendritic cell subset expressing a chemokine receptor, XCR12018

    • Author(s)
      Tsuneyasu Kaisho
    • Organizer
      15th International Symposium on Dendritic Cells
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] A case of neonatal-onset proteasome-associated autoinflammatory syndrome resembling but distinct from Nakajo-Nishimura syndrome2018

    • Author(s)
      Noriko Kinjo, Hiroyuki Mishima, Akira Kinoshita, Koh-Ichiro Yoshiura,Tsunehiro Mizushima, Jun Hamazaki, Shigeo Murata, Hiroaki Hemmi, Tsuneyasu Kaisho,Nobuo Kanazawa
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] 新規LIG4遺伝子変異を導入したLIG4症候群モデルマウス A mouse model of LIG4 syndrome with novel LIG4 mutation2018

    • Author(s)
      山下友佑、田村志宣、福田有里、小笹俊哉、金澤伸雄、邊見弘明、吉浦孝一郎、改正恒康、園木孝志
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Impaired development of dendritic cells in proteasome subunit mutant mice2018

    • Author(s)
      Hiroaki Hemmi, Toshiya Ozasa, Akira Kinoshita, Takashi Kato, Takashi Orimo, Izumi Sasaki, Yuri Fukuda-Ohta, Noriko Kinjo, Koh-Ichiro Yoshiura, Tsunehiro Mizushima,Nobuo Kanazawa, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 新規LIG4遺伝子変異を導入したLIG4症候群モデルマウス A mouse model of LIG4 syndrome with novel LIG4 mutation2018

    • Author(s)
      山下友佑、田村志宣、福田有里、小笹俊哉、金澤伸雄、邊見弘明、吉浦孝一郎、改正恒康、園木孝志
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Current overview of functions and development of dendritic cells2018

    • Author(s)
      Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] The mechanism of action of Spi-B in transcriptional activation of the interferon-α4 gene2018

    • Author(s)
      Ryo Miyazaki, Hiroyuki Saiga, Tsuneyasu Kaisho, Katsuaki Hoshino.
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Analysis of mice carrying a novel mutation in a proteasome subunit gene identified in anautoinflammatory disease patient2018

    • Author(s)
      Toshiya Ozasa, Hiroaki Hemmi, Akira Kinoshita, Takashi Kato, Takashi Orimo, Izumi Sasaki, Yuri Fukuda-Ohta, Noriko Kinjo, Koh-Ichiro Yoshiura, Tsunehiro Mizushima, Nobuo Kanazawa, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Time-resolved systems analysis of virus infection fate regulation: the XCL1-XCR1 communication axis links T cell exhaustion with effector maintenance2018

    • Author(s)
      J. Argilaguet, M. Pedragosa, A. Esteve-Codina, G. Riera, E. Vidal, C. Peligero-Cruz, D. Andreu, T. Kaisho, G. Bocharov, B. Ludewig, S. Heath, A. Meyerhans
    • Organizer
      15th International Symposium on Dendritic Cells
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Osteoprotegerin-dependent M-cell self-regulation balances gut infection and immunity2018

    • Author(s)
      Shunsuke Kimura, Yutaka Nakamura, Nobuhide Kobayashi, Tsuneyasu Kaisho, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Sox8 is essential for the differentiation of M cells and antigen-specific IgA response2018

    • Author(s)
      Nobuhide Kobayashi, Shunsuke Kimura, Yutaka Nakamura, Takashi Kanaya, Tsuneyasu Kaisho, Hiroshi Ohno, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] XCR1+DCへの選択的な送達を目的とした新規抗がんワクチンの開発2018

    • Author(s)
      宮本篤、勝田将裕、邊見弘明、宮澤基樹、北畑裕司、水本有紀、小林良平、改正恒康、山上裕機
    • Organizer
      第46回和歌山悪性腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Foxp3+ regulatory T cells are expanded by ultraviolet B-exposed PD-L1+ skin dendritic cell expressing a unique set of genes in a CSF1-independent manner2018

    • Author(s)
      Sayuri Yamazaki, Mizuyu Odanaka, Hiroaki Shime, Masaki Imai, Akiko Nishioka, Saori Kasuya, Dieter Riethmacher, Hiroaki Hemmi, Tsuneyasu Kaisho, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita
    • Organizer
      International Investigative Dermatology 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] 皮膚科医に知っていただきたい樹状細胞の機能的および病理的意義2018

    • Author(s)
      改正恒康、邊見弘明、小笹俊哉
    • Organizer
      第117回日本日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Cancer Vaccine Composed of Whole Tumor Cells Genetically Modified to Secrete the XCL12018

    • Author(s)
      Atsushi Miyamoto, Hemmi Hiroaki, Yuki Mizumoto, Masahiro Katsuda, Yuri Ohta,Katsuaki Hoshino, Hiroki Yamaue, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] The mechanism of action of Spi-B in transcriptional activation of the interferon-α4 gene2018

    • Author(s)
      Ryo Miyazaki, Hiroyuki Saiga, Tsuneyasu Kaisho, Katsuaki Hoshino
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Current overview of functions and development of dendritic cells2018

    • Author(s)
      Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 皮膚科医に知っていただきたい樹状細胞の機能的および病理的意義2018

    • Author(s)
      改正恒康、邊見弘明、小笹俊哉
    • Organizer
      第117回日本日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Cholera toxin B can induce interleukine-1β production in peritoneal macrophages through activation of pyrin inflammasome2018

    • Author(s)
      Izumi Sasaki, Takashi Orimo, Hiroaki Hemmi, Toshiya Ozasa, Yuri Fukuda-Ohta, Mio Morinaka, Shinji Fukuda, Koichi Furukawa, Etsushi Kuroda, Ken J. Ishii, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] XCR1+DCへの選択的な送達を目的とした新規抗がんワクチンの開発2018

    • Author(s)
      宮本篤、勝田将裕、邊見弘明、宮澤基樹、北畑裕司、水本有紀、小林良平、改正恒康、山上裕機
    • Organizer
      第46回和歌山悪性腫瘍研究会
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Current overview of functions and development of dendritic cells2018

    • Author(s)
      Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Successful treatment of psoriatic inflammation restores hyperglycemia2018

    • Author(s)
      Kyoko Ikumi, Mizuyu Odanaka, Hiroaki Shime, Masaki Imai, Osamu Taguchi, Hiroaki Hemmi, Tsuneyasu Kaisho, Sayuri Yamazaki, Akimichi Morita
    • Organizer
      International Investigative Dermatology 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Analysis of mice carrying a novel mutation in a proteasome subunit gene identified in anautoinflammatory disease patient2018

    • Author(s)
      Toshiya Ozasa, Hiroaki Hemmi, Akira Kinoshita, Takashi Kato, Takashi Orimo, Izumi Sasaki, Yuri Fukuda-Ohta, Noriko Kinjo, Koh-Ichiro Yoshiura, Tsunehiro Mizushima, Nobuo Kanazawa, Tsuneyasu Kaisho
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] 中條-西村症候群からプロテアソーム関連自己炎症/免疫不全症候群へ2018

    • Author(s)
      金澤伸雄、中谷友美、原知之、稲葉豊、国本佳代、古川福実、神人正寿、金城紀子、水島恒裕、三嶋博之、木下晃、吉浦孝一郎、加藤喬、福田有里、邊見弘明、改正恒康
    • Organizer
      第25回分子皮膚科学フォーラム
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Osteoprotegerin-dependent M-cell self-regulation balances gut infection and immunity2018

    • Author(s)
      Shunsuke Kimura, Yutaka Nakamura, Nobuhide Kobayashi, Tsuneyasu Kaisho, Koji Hase
    • Organizer
      第47回日本免疫学会総会・学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Roles of arginine and methionine metabolism in cholera toxin-induced adjuvant effects.2017

    • Author(s)
      I. Sasaki, T. Orimo, H. Hemmi, T. Ozasa, Y. Fukuda, S. Fukuda, T. Kaisho.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Decline of lysyl oxidase protein causes acute aortic dissection in Spi-B knockout mice.2017

    • Author(s)
      A. Taruya, A. Kimura, Y. Ishida, M. Nosaka, K. Yumi, I. Sasaki, T. Kaisho, T. Kondo.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Spi-Bは圧負荷による心不全の病態形成において炎症と線維化を抑制して保護的に機能する2017

    • Author(s)
      1.木村章彦、福田有里、加藤喬、佐々木泉、改正恒康、近藤稔和
    • Organizer
      第38回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] An Ets family member, Ets2 is required for Cholera toxin-induced arginase-1 gene expression.2017

    • Author(s)
      K. Negoro, M. Tane, M. Morinaka, Y. Fukuda, I. Sasaki, T. Kaisho
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Spi-B plays a protective role in pressure overload-induced heart failure through attenuation of cardiac inflammation.2017

    • Author(s)
      1.A. Kimura, Y. Ihida, M. Nosaka, I. Sasaki, H. Yamamoto, Y. Kuninaka, T. Kato, Y. Fukuda, T. Kaisho, T. Kondo.
    • Organizer
      22nd World Congress Heart Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 樹状細胞サブセットに注目したがんペプチドワクチンの開発2017

    • Author(s)
      2.水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、松田健司、尾島敏康 早田啓治、邊見弘明、改正恒康、山上裕機
    • Organizer
      第38回 癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] がん抗原ペプチドの生体内樹状細胞サブセット送達によるワクチン療法の開発2017

    • Author(s)
      4.水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、尾島敏康、松田健司、早田啓治、邊見弘明、改正恒康、山上裕機
    • Organizer
      第30回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Spi-C inhibits expression of a subset of Toll-like receptor 4-inducible genes in intestinal CX3CR1high macrophages and prevents colonic inflammation.2017

    • Author(s)
      H. Kayama, M. Kohyama, H. Arase, T. Kaisho, K. Takeda.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Spi-Bは圧負荷による心不全の病態形成において炎症と線維化を抑制して保護的に機能する2017

    • Author(s)
      1.木村章彦、福田有里、加藤喬、佐々木泉、改正恒康、近藤稔和
    • Organizer
      第38回日本炎症・再生医学会
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] Spi-C inhibits expression of a subset of Toll-like receptor 4-inducible genes in intestinal CX3CR1high macrophages and prevents colonic inflammation.2017

    • Author(s)
      H. Kayama, M. Kohyama, H. Arase, T. Kaisho, K. Takeda.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Spi-B plays a protective role in pressure overload-induced heart failure through attenuation of cardiac inflammation.2017

    • Author(s)
      1.A. Kimura, Y. Ihida, M. Nosaka, I. Sasaki, H. Yamamoto, Y. Kuninaka, T. Kato, Y. Fukuda, T. Kaisho, T. Kondo.
    • Organizer
      22nd World Congress Heart Disease(国際学会)
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] 樹状細胞サブセットに注目したがんペプチドワクチンの開発2017

    • Author(s)
      2.水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、松田健司、尾島敏康 早田啓治、邊見弘明、改正恒康、山上裕機
    • Organizer
      第38回 癌免疫外科研究会
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] 粘膜感染防御における腸管特殊上皮M細胞の役割の解明2017

    • Author(s)
      中村有孝、國澤純、改正恒康、清野宏、長谷耕二
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] An Ets family member, Ets2 is required for Cholera toxin-induced arginase-1 gene expression.2017

    • Author(s)
      K. Negoro, M. Tane, M. Morinaka, Y. Fukuda, I. Sasaki, T. Kaisho
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] An Ets family member, Ets2 is required for Cholera toxin-induced arginase-1 gene expression.2017

    • Author(s)
      K. Negoro, M. Tane, M. Morinaka, Y. Fukuda, I. Sasaki, T. Kaisho
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Decline of lysyl oxidase protein causes acute aortic dissection in Spi-B knockout mice.2017

    • Author(s)
      A.Taruya, A. Kimura, Y. Ishida, M. Nosaka, K. Yumi, I. Sasaki, T. Kaisho, T. Kondo.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] がん抗原ペプチドの生体内樹状細胞サブセット送達によるワクチン療法の開発2017

    • Author(s)
      4.水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、尾島敏康、松田健司、早田啓治、邊見弘明、改正恒康、山上裕機
    • Organizer
      第30回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Roles of arginine and methionine metabolism in cholera toxin-induced adjuvant effects.2017

    • Author(s)
      I.Sasaki, T. Orimo, H. Hemmi, T. Ozasa, Y. Fukuda, S. Fukuda, T. Kaisho.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] 樹状細胞サブセットに注目したがんペプチドワクチンの開発2017

    • Author(s)
      2.水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、松田健司、尾島敏康 早田啓治、邊見弘明、改正恒康、山上裕機
    • Organizer
      第38回 癌免疫外科研究会
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Roles of arginine and methionine metabolism in cholera toxin-induced adjuvant effects.2017

    • Author(s)
      I.Sasaki, T. Orimo, H. Hemmi, T. Ozasa, Y. Fukuda, S. Fukuda, T. Kaisho.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Spi-B plays a protective role in pressure overload-induced heart failure through attenuation of cardiac inflammation.2017

    • Author(s)
      1.A. Kimura, Y. Ihida, M. Nosaka, I. Sasaki, H. Yamamoto, Y. Kuninaka, T. Kato, Y. Fukuda, T. Kaisho, T. Kondo.
    • Organizer
      22nd World Congress Heart Disease(国際学会)
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] がん抗原ペプチドの生体内樹状細胞サブセット送達によるワクチン療法の開発2017

    • Author(s)
      4.水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、尾島敏康、松田健司、早田啓治、邊見弘明、改正恒康、山上裕機
    • Organizer
      第30回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Spi-Bは圧負荷による心不全の病態形成において炎症と線維化を抑制して保護的に機能する2017

    • Author(s)
      1.木村章彦、福田有里、加藤喬、佐々木泉、改正恒康、近藤稔和
    • Organizer
      第38回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] Spi-C inhibits expression of a subset of Toll-like receptor 4-inducible genes in intestinal CX3CR1high macrophages and prevents colonic inflammation.2017

    • Author(s)
      H. Kayama, M. Kohyama, H. Arase, T. Kaisho, K. Takeda.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] 粘膜感染防御における腸管特殊上皮M細胞の役割の解明2017

    • Author(s)
      中村有孝、國澤純、改正恒康、清野宏、長谷耕二
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04088
  • [Presentation] Decline of lysyl oxidase protein causes acute aortic dissection in Spi-B knockout mice.2017

    • Author(s)
      A.Taruya, A. Kimura, Y. Ishida, M. Nosaka, K. Yumi, I. Sasaki, T. Kaisho, T. Kondo.
    • Organizer
      第46回日本免疫学会総会学術集会記録
    • Data Source
      KAKENHI-PROJECT-17K19568
  • [Presentation] 粘膜感染防御における腸管特殊上皮M細胞の役割の解明2017

    • Author(s)
      中村有孝、國澤純、改正恒康、清野宏、長谷耕二
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-17H05799
  • [Presentation] 治療抵抗性EBウイルス関連血球貪食症候群を発症したX連鎖性知的障害例における新規CCDC22遺伝子変異の同定2017

    • Author(s)
      山下友佑, 田村志宣, 岩橋吉史, 佐々木泉, 西川彰則, 金澤伸雄, 邊見弘明, 村田晋一, 改正恒康, 大島孝一, 今留謙一, 吉浦孝一郎, 園木孝志.
    • Organizer
      第10回日本免疫不全症研究会
    • Place of Presentation
      東京(千代田)
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Involvement of XCR1-expressing dendritic cells through the XCR1-XCL1 chemokine axis in intestinal immune homeostasis.2016

    • Author(s)
      T. Ohta, H. Hemmi, T. Kaisho.
    • Organizer
      International Congress of Immunology
    • Place of Presentation
      (Melbourne, Australia)
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Dose Juzen-Taiho-To have immuno-suppressive effect?2016

    • Author(s)
      K. Kanno, M. Odanaka, M. Imai, A. Nishioka, M. Nose, H. Hemmi, T. Kaisho, A. Morita, S. Yamazaki.
    • Organizer
      第45回日本免疫学会総会
    • Place of Presentation
      沖縄(宜野湾)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] The absence of Spi-B exaggerates acute aortic dissection in mice.2016

    • Author(s)
      A. Taruya, A. Kimura, M. Nosaka, Y. Ishida, Y. Kuninaka, I. Sasaki, Y. Fukuda, T. Kaisho, T. Kondo.
    • Organizer
      第45回日本免疫学会総会
    • Place of Presentation
      沖縄(宜野湾)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] How do XCR1-expressing dendritic cells function in vivo?2016

    • Author(s)
      T. Kaisho
    • Organizer
      4th Cluster Science Days
    • Place of Presentation
      (Bonn, Germany)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Intestinal M cells contribute to maintenance of gut immune homeostasis.2016

    • Author(s)
      Y. Nakamura, C. Yarimizu, T. Kaisho, J. Kunisawa, H. Kiyono, K. Hase.
    • Organizer
      第45回日本免疫学会総会
    • Place of Presentation
      沖縄(宜野湾)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] XCR1+樹状細胞をターゲットとした新規がんペプチドワクチン療法の開発2016

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、宮本篤、中森幹人、尾島敏康、早田啓治、北谷純也、邊見弘明、改正恒康、山上裕機
    • Organizer
      第29回日本バイオセラピィ学会学術集会総会
    • Place of Presentation
      福岡(久留米)
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] XCR1+樹状細胞をターゲットとした新規がんペプチドワクチン療法の開発2016

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、津村亜矢子、尾島敏康、中森幹人、邊見弘明、改正恒康、山上裕機
    • Organizer
      第71回日本消化器外科学会総会
    • Place of Presentation
      徳島(徳島)
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Chemokine-directed cancer antigen peptide delivery to the XCR1+ dendritic cell subset.2016

    • Author(s)
      Y. Mizumoto, H. Hemmi, M. Katsuda, M. Sugiyama, T. Ohta, Y. Fukuda, A. Miyamoto, H. Yamaue T. Kaisho.
    • Organizer
      第45回日本免疫学会総会
    • Place of Presentation
      沖縄(宜野湾)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Dynamic control of inflammatory signaling by organelles in DC/macrophages.2016

    • Author(s)
      T. Kaisho
    • Organizer
      第45回日本免疫学会総会
    • Place of Presentation
      沖縄(宜野湾)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Crosstalk between XCR1-expressing dendritic cells and intenstinal T cells keeps intenstinal homeostasis through the XCR1-XCL1 chemokine axis.2016

    • Author(s)
      T. Ohta, H. Hemmi, Y. Fukuda, I. Sasaki, T. Orimo, T. Kaisho.
    • Organizer
      第45回日本免疫学会総会
    • Place of Presentation
      沖縄(宜野湾)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Clec9A-mediated induction of Tfh and B cell responses.2016

    • Author(s)
      Y. Kato, M. Lahoud, T. Kaisho, K. Shortman, S. Mueller, I. Caminschi, W. Heath.
    • Organizer
      International Congress of Immunology
    • Place of Presentation
      (Melbourne, Australia)
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Intestinal immune homeostasis regulated by a dendritic cell subset expressing a chemokine, XCR1.2016

    • Author(s)
      T. Kaisho, T. Ohta, I. Sasaki, T. Orimo, T. Kato and H. Hemmi.
    • Organizer
      Shandong-Wakayama Medical & Nursing Plenary Lecture 2016
    • Place of Presentation
      (Wakayama, Japan)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] XCR1+樹状細胞をターゲットとした新規がんペプチドワクチン療法の開発2016

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、津村亜矢子、宮本篤、尾島敏康、中森幹人、松田健司 早田啓治、改正恒康、山上裕機
    • Organizer
      第37回 癌免疫外科研究会
    • Place of Presentation
      埼玉(川越)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Homeostatic roles of intestinal dendritic cells expressing a chemokine receptor, XCR1, and XCL1-XCR1 chemokine system.2016

    • Author(s)
      T. Ohta, H. Hemmi, T. Kaisho.
    • Organizer
      The 24th International Symposium on Molecular Cell Biology of Macrophages
    • Place of Presentation
      (Tokyo, Japan)
    • Year and Date
      2016-06-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Critical roles of a dendritic cell subset expressing a chemokine receptor, XCR1.2016

    • Author(s)
      T. Kaisho
    • Organizer
      Mechanisms of Molecular and Cellular Immunity
    • Place of Presentation
      (Berlin, Germany)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] CD8 T cells orchestrate pDC-XCR1 DC spatial and functional cooperativity to optimize priming.2016

    • Author(s)
      A. Brewitz, S. Eickhoff, S. Dahling, T. Quast, S. Bedoui, R. A. Kroczek, C. Kurts, N. Garbi, T. Kaisho, W. Kolanus, M. Colonna, M. lannacone, R. N. Germain and W. Kastenmuller.
    • Organizer
      4th Cluster Science Days
    • Place of Presentation
      (Bonn, Germany)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Spi-B plays a protective role in pressure overload-induced heart failure through attenuation of cardiac inflammation.2016

    • Author(s)
      A. Kimura, Y. Ishida, M. Nosaka, Y. Kuninaka, I. Sasaki, Y. Fukuda, T. Kaisho, T. Kondo.
    • Organizer
      第45回日本免疫学会総会
    • Place of Presentation
      沖縄(宜野湾)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Development of new cancer peptide vaccine therapy that targets XCR1+ dendritic cell2016

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、津村亜矢子、宮本篤、中森幹人、尾島敏康、邊見弘明、改正恒康、山上裕機
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      神奈川(横浜)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] XCR1+樹状細胞をターゲットとしたがんワクチン療法の開発2016

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、津村亜矢子、宮本篤、尾島敏康、中森幹人、松田健司、早田啓治、邊見弘明、改正恒康、山上裕機
    • Organizer
      第27回 日本消化器癌発生学会総会
    • Place of Presentation
      鹿児島(鹿児島)
    • Year and Date
      2016-09-15
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Metabolic basis for cholera toxin-induced IL-1beta production in synergy with lipopolysaccharides.2016

    • Author(s)
      I. Sasaki, S. Fukuda, T. Orimo, H. Hemmi, Y. Fukuda, T. Ohta, T. Kaisho.
    • Organizer
      第45回日本免疫学会総会
    • Place of Presentation
      沖縄(宜野湾)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] In vivo behavior and functions of a dendritic cell subset expressing a chemokine receptor, XCR1.2015

    • Author(s)
      T. Kaisho
    • Organizer
      Shandong University-Wakayama Medical University Medical and Nursing Symposium
    • Place of Presentation
      Shandong, China
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Intestinal immune homeostasis is regulated by XCR1-expressing dendritic cells through XCL1-XCR1 axis.2015

    • Author(s)
      T. Ohta, H. Hemmi, T. Kaisho.
    • Organizer
      LC2015 14th Intermnational Workshop on Langerhans Cells
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] XCR1+樹状細胞をターゲットとした新規がんペプチドワクチン療法の開発2015

    • Author(s)
      水本有紀、勝田将裕、宮澤基樹、北畑裕司、津村亜矢子、尾島敏康、早田啓治、北谷純也、堀田司、松田健司、改正恒康、山上裕機
    • Organizer
      第28回日本バイオセラピィ学会学術集会総会
    • Place of Presentation
      Saitama, Japan
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Role of the polyamine pathway in Choleta toxin-induces production of proinflammatory cytokines.2015

    • Author(s)
      T. Orimo, I. Sasaki, S. Fukuda, H. Hemmi, Y. Fukuda, T. Kaisho.
    • Organizer
      第44回日本免疫学会総会
    • Place of Presentation
      Hokkaido, Japan
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Intestinal Immune Homeostasis Regulated by Dendritic Cells.2015

    • Author(s)
      改正恒康
    • Organizer
      The 3rd Homeostatic Inflammation International Symposium
    • Place of Presentation
      東京
    • Year and Date
      2015-01-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Effective anti-tumor immunity provoked by chemokine-directed delivering to a DC subset with high CTL-inducing ability.2015

    • Author(s)
      Y. Mizumoto, H. Hemmi, M. Katsuda, T.Ohta, Y. Fukuda, H, Yamaue, T. Kaisho.
    • Organizer
      第44回日本免疫学会総会
    • Place of Presentation
      Hokkaido, Japan
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Fbxo21, a component of ubiquitin E3 ligase complex, associates with PDLIM2 and specifically rerulates NF-κB-mediated inflammatory sighnaling.2015

    • Author(s)
      T. Tanaka, A. Shibazaki, R. Ono, T. Kaisho.
    • Organizer
      第44回日本免疫学会総会
    • Place of Presentation
      Hokkaido, Japan
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] Intestinal Immune Homeostasis Regulated by Dendritic Cells.2015

    • Author(s)
      改正恒康
    • Organizer
      The 3rd Homeostatic Inflammation International Symposium
    • Place of Presentation
      東京大学医科学研究所(東京都、港区)
    • Year and Date
      2015-01-31
    • Invited
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Regulatory mechanisms for inflammatory cytokine production by metabolic pathways.2014

    • Author(s)
      改正恒康
    • Organizer
      第87回日本生化学会大会 The 87th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      京都国際会館
    • Year and Date
      2014-10-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] 樹状細胞を介した新規の生体恒常性維持機構2014

    • Author(s)
      改正恒康
    • Organizer
      第50回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      和歌山
    • Year and Date
      2014-12-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293106
  • [Presentation] 樹状細胞を介した新規の生体恒常性維持機構2014

    • Author(s)
      改正恒康
    • Organizer
      第50回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      和歌山県立医科大学(和歌山県、和歌山市)
    • Year and Date
      2014-12-05
    • Invited
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Regulatory mechanisms for inflammatory cytokine production by metabolic pathways.2014

    • Author(s)
      改正恒康
    • Organizer
      第87回日本生化学会大会 The 87th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      京都国際会館(京都府、京都市)
    • Year and Date
      2014-10-16
    • Invited
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Function of XCR1-expressing dendric cells in oral tolerance2013

    • Author(s)
      H. Hemmi, M. Sugiyama, T. Ohta, I. Sasaki, C. Yamazaki, T. Tanaka, K. Hoshino, T. Kaisho
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective IFN- β2013

    • Author(s)
      T. Kawashima, H Yan, Z. Guo, J. Carreras, R. Uchiyama, R. Fukui, T. Kaisho , S. Akira, K. Miyake, H. Tsutsui, T. Saito, N.M.Tsuji
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] The role of M cells in intestinal helminthic infection2013

    • Author(s)
      C. Shimokawa, T. Kanaya, T. Kaisho
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Molecular mechanisms for dendritic cell subset functions.2013

    • Author(s)
      T. Kaisho
    • Organizer
      Agricultural Biotechnology Symposium ‘Immune Modulation and Bioconvergence
    • Place of Presentation
      ソウル、韓国
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Critical in vivo roles of dendritic cells expressing a chemokine receptor, XCR12013

    • Author(s)
      T. Kaisho
    • Organizer
      The 2013 Fall Conference of the Korean Association of Immunologists
    • Place of Presentation
      ソウル、韓国
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] The transcription factor IRF8 is required for basophil development2013

    • Author(s)
      H. Sasaki, D. Kurotaki, N. Osato, I. Sasaki, C. Kaneda, A. Nishiyama, T.Kaisho , H. C. III. Morse, K. Ozato, T. Tamura
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Long-term memory T cell response induced by adjuvant role of iNKT cells2013

    • Author(s)
      K. Shimizu, Y. Sato, J. Shinga, M. Asakura, T. Kaisho
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Critical roles of dendritic cells expressing a chemokine receptor XCR1.2013

    • Author(s)
      T. Kaisho, H. Hemmi, M. Sugiyama, T. Ohta.
    • Organizer
      The Joint international Meeting of The 78th Meeting of the Japanese Society of Interferon and Cytokine Research and The 21st International Symposium on Molecular Cell Biology of Macrophage
    • Place of Presentation
      都市センターホテル、東京
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Molecular mechanisms for dendritic cell subset functions.2013

    • Author(s)
      T. Kaisho.
    • Organizer
      Agricultural Biotechnology Symposium ‘Immune Modulation and Bioconvergence
    • Place of Presentation
      Seoul(Korea)
    • Year and Date
      2013-11-06
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] A novel mechanism to generate the intestinal intraepithelial T lymphocytes by XCR-expressing dendric cells2013

    • Author(s)
      T. Ohta, H. Hemmi, C. Yamazaki, M. Sugiyama, I. Sasaki, K. Hoshino, T. Kaisho
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] The crucial role of Spi-B transcription factor in M-cell differentiation.2013

    • Author(s)
      T. Kanaya, K. Hase, T. Kaisho, I.R.Williams, H.Ohno.
    • Organizer
      The 16th International Congress of Mucosal Immunology.
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Lactococcus lactis subsp. cremoris FC triggers IFN-ɤproduction from NK and T cells via IL-12 and IL-182013

    • Author(s)
      Kosaka, H. Yan, H. Tsutsui, T. Kaisho , N. Tsuji
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] In vivo roles of XCR1-expressing dendric cells2013

    • Author(s)
      T. Kaisho
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Year and Date
      2013-12-12
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] In vivo roles of XC chemokine receptor 1-expressing dendritic cells.2013

    • Author(s)
      T. Ohta, H. Hemmi, C. Yamazaki, M. Sugiyama, I. Sasaki, K. Hoshino, T. Kaisho.
    • Organizer
      The 15th International Congress of Immunology
    • Place of Presentation
      ミラノ、イタリア
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] In vivo roles of dendritic cells expressing a chemokine receptor, XCR12013

    • Author(s)
      T. Kaisho
    • Organizer
      France-Japan Joint Forum “Frontiers in Innate Immunity'
    • Place of Presentation
      ストラスブルグ、フランス
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] In vivo roles of XCR1-expressing dendric cells.2013

    • Author(s)
      T. Kaisho
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張メッセ 千葉
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] IL-27 affects immune responses via regulation of prostaglandin E2 production by macrophages2012

    • Author(s)
      Y. Sato, S. Suzuki, H. Hara, T. Kaisho , H. Yoshida
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Dendritic cell subsets in inflammation.2012

    • Author(s)
      T. Kaisho
    • Organizer
      The 12th Biennial International Endotoxin & Innate Immunity Society (IEIIS) Meeting
    • Place of Presentation
      学術総合センター(東京都千代田区)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Ablation of a dendritic cell subset expressing XC chemokine receptor 1 in vivo.2012

    • Author(s)
      H. Hemmi, C. Yamazaki, M. Sugiyama, T.Ohta, I. Sasaki, K. Hoshino, T. Kaisho
    • Organizer
      The 12th International Symposium on Dendritic Cells, DC 2012
    • Place of Presentation
      Daegu, Korea
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] A non-synonymous SNP (single nucleotide polymorphism) of PDLIM4 is associated with susceptibility of rheumatoid arthritis and Graves diseases2012

    • Author(s)
      T. Tanaka, Y. Kochi, K. Yamamoto, T. Kaisho
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake.2012

    • Author(s)
      T. Kanaya, K. Hase, T Kaisho, I. Williams, H. Ohno
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Island, Hyogo
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Roles of an Ets family transcription factor, Spi-B, in plasmacytoid dendritic cell development in the bone marrow.2012

    • Author(s)
      I. Sasaki, K. Hoshino, H. Hemmi, M.Sugiyama, T. Yamaguchi, T. Kaisho
    • Organizer
      IEIIS2012 Homeostatic Inflammation Symposium
    • Place of Presentation
      Tokyo, Japan.
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] A non-synonymous SNP(single nucleotide polymorphism) of PDLIM4 is associated with susceptibility of rheumatoid arthritis and Graves diseases.2012

    • Author(s)
      T. Tanaka, Y. Kochi, K. Yamamoto, T. Kaisho
    • Organizer
      第41回日本免疫学会総会・学術集会記録41:74, 2012
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Visualization of Inflammasome activation : monitoring caspase-1 activity in living cells by a genetically-encoded probe SCAT12012

    • Author(s)
      劉霆, 山口良文, 星野克明, 改正恒康, 竹本研, 倉永英里奈, 三浦正幸
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] 樹状細胞サブセット機能を制御する分子機構2012

    • Author(s)
      改正恒
    • Place of Presentation
      大阪市立大学(大阪)
    • Year and Date
      2012-01-12
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] IκB-ζ-deficiency in Epithelial Cells Elicits Sjogren's Syndrome-like Autoimmune Disease2012

    • Author(s)
      A. Okuma, K. Hoshino, T.Kaisho , T. Muta
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Critical role of Siglec-H in the function of plasmacytoid dendritic cells for the regulation of inflammation and T cell immunity in vivo2012

    • Author(s)
      R. Murakami, H. Takagi, T. Fukaya, O. Ohara, T. Kaisho, B. Malissen, K. Sato.
    • Organizer
      The 12th International Symposium on Dendritic Cells, DC 2012
    • Place of Presentation
      Daegu, Korea
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] IL-27 affects immune responses via regulation of prostaglandin E2 production by macrophages.2012

    • Author(s)
      Y. Sato, S. Suzuki, H. Hara, T. Kaisho, H. Yoshida
    • Organizer
      第41回日本免疫学会総会・学術集会記録41:92,2012
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] The Ets transcription factor Spi-B is essential for M-cell differentiation2012

    • Author(s)
      T. Kanaya, K. Hase, T. Kaisho , R. W. Ifor, H Ohno
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Analysis of in vivo function of XC chemokine receptor-expressing dendric cells.2012

    • Author(s)
      M. Sugiyama, H. Hemmi, C. Yamazaki, T. Ohta, I. Sasaki, K. Hoshino, T. Kaisho
    • Organizer
      第41回日本免疫学会総会・学術集会記録41:158, 2012
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo2012

    • Author(s)
      H. Takagi, R. Murakami, T. Fukaya, O. Ohara, T. Kaisho, B. Malissen, K. Sato
    • Organizer
      The 12th International Symposium on Dendritic Cells, DC 2012
    • Place of Presentation
      Daegu, Korea
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] サイエンスカフェ免疫研究の最前線2012

    • Author(s)
      改正恒
    • Organizer
      樹状細胞は免疫のキープレーヤー
    • Place of Presentation
      大阪
    • Year and Date
      2012-04-30
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] -deficiency in Epithelial Cells Elicits Sjogren's Syndrome-like Autoimmune Disease.2012

    • Author(s)
      A. Okuma, K. Hoshino, T.Kaisho, T. Muta
    • Organizer
      第41回日本免疫学会総会・学術集会記録 41:33,2012
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] In vivo roles of XC chemokine receptor 1-expressing dendritic cells.2012

    • Author(s)
      M. Sugiyama, H. Hemmi, C. Yamazaki, T.Ohta, I. Sasaki, K. Hoshino, T. Kaisho
    • Organizer
      IEIIS2012 Homeostatic Inflammation Symposium
    • Place of Presentation
      Tokyo, Japan.
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Spi-B is critical for plasmacytoid dendric cell development in bone marrow2012

    • Author(s)
      I. Sasaki, K. Hoshino, H. Hemmi, M. Sugiyama, T. Yamaguchi, T. Kaisho
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] I B --deficient Mice Develop Sjogren's Syndrome-like Chronic Inflammation Caused by Dysregulation of Epithelial Homeostasis.2012

    • Author(s)
      A. Okuma, K. Hoshino, T. Kaisho, T. Muta
    • Organizer
      IEIIS2012 Homeostatic Inflammation Symposium
    • Place of Presentation
      Tokyo, Japan.
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Dendritic cell subsets in inflammation2012

    • Author(s)
      T. Kaisho
    • Organizer
      The 12th Biennial International Endotoxin Innate Immunity Society (IEIIS) Meeting
    • Place of Presentation
      学術総合センター(東京千代田区)
    • Year and Date
      2012-10-23
    • Invited
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake2012

    • Author(s)
      T. Kanaya, K. Hase, T Kaisho, I. Williams, H. Ohno.
    • Organizer
      DC2012
    • Place of Presentation
      Daege, Korea
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Visualization of Inflammasome activation: monitoring caspase-1 activity in living cells by a genetically-encoded probe SCAT12012

    • Author(s)
      T. Liu, Y. Yamaguchi, K. Hoshino, T. Kaisho, K. Takemoto, E. Kuranaga, M. Miura
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] The Ets transcription factor Spi-B is essential for M-cell differentiation2012

    • Author(s)
      T. Kanaya, K. Hase, T. Kaisho, R. W. Ifor, H Ohno
    • Organizer
      第41回日本免疫学会総会・学術集会記録 41:210,2012
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Analysis of in vivo function of XC chemokine receptor-expressing dendric cells2012

    • Author(s)
      M. Sugiyama, H. Hemmi, C. Yamazaki, T. Ohta, I. Sasaki, K. Hoshino, T. Kaisho
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Long-term memory T cell response induced by adjuvant role of iNKT cells2012

    • Author(s)
      K. Shimizu, M. Asakura, J. Shinga, Y. Sato, K. Hoshino, T.Kaisho , T. Ezaki, S. Fujii
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Spi-B is critical for plasmacytoid dendric cell development in bone marrow.2012

    • Author(s)
      I. Sasaki, K. Hoshino, H. Hemmi, M. Sugiyama, T. Yamaguchi, T. Kaisho
    • Organizer
      第41回日本免疫学会総会・学術集会記録 41:162,2012
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Long-term memory T cell response induced by adjuvant role of iNKT cells.2012

    • Author(s)
      K. Shimizu, M. Asakura, J. Shinga, Y. Sato, K. Hoshino, T.Kaisho, T. Ezaki, S. Fujii.
    • Organizer
      第41回日本免疫学会総会・学術集会記録41:133,2012
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Dendritic cell subsets in inflammation.2012

    • Author(s)
      T. Kaisho
    • Organizer
      The 12th Biennial International Endotoxin & Innate Immunity Society (IEIIS) Meeting
    • Place of Presentation
      学術総合センター(東京都)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] In vivo ablation of XC chemokine receptor 1-expressing dendritic cell subset.2012

    • Author(s)
      M. Sugiyama, H. Hemmi, C. Yamazaki, I. Sasaki, T. Ohta, K. Hoshino, T. Kaisho.
    • Organizer
      20th International Symposium on Molecular Cell Biology of Macrophages 2012
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] 自然免疫~感染の検知システム2011

    • Author(s)
      改正恒康
    • Organizer
      免疫ふしぎ未来
    • Place of Presentation
      日本科学未来館(東京)
    • Year and Date
      2011-08-21
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 核酸系免疫アジュバントに対する樹状細胞サブセットの応答機構2011

    • Author(s)
      改正恒康
    • Organizer
      第29回日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      大分
    • Year and Date
      2011-02-10
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] PDLIM4 negatively regulates STAT signaling by recruiting protein tyrosine phosphatases.2011

    • Author(s)
      T. Hirashima, T. Kaisho, T. Tanaka.
    • Organizer
      第40回日本免疫学会総会・学術集会記録 40:109, 2011
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Importance of chemokines system between human BDCA3+ dendritic cells and NK cells in innate cytotoxic response2011

    • Author(s)
      T. Ito, R. Miyamoto, C. Yamazaki, K. Hoshino, T. Kaisho, S. Nomura.
    • Organizer
      第40回日本免疫学会総会・学術集会記録 40:197, 2011
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Evaluation of SCAT1: a genetically-encoded probe for detecting activation of caspase-1 in living cells2011

    • Author(s)
      K. Shikada, Y. Yamaguchi, T. Liu, K. Takemoto, K. Hoshino, T. Kaisho. E. Kuranaga, M. Miura
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] PDLIM4による STAT シグナルの負の制御機構2011

    • Author(s)
      平島健志, 改正恒康, 田中貴志
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] 核酸系免疫アジュバントに対する樹状細胞サブセットの応答機構2011

    • Author(s)
      改正恒康
    • Organizer
      第29回日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      大分
    • Year and Date
      2011-02-10
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 樹状細胞機能制御の分子基盤2011

    • Author(s)
      改正恒康
    • Organizer
      免疫サマースクール
    • Place of Presentation
      ラフォーレ蔵王(宮城県)
    • Year and Date
      2011-08-01
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Dendritic cell sensing and responses for nucleic acid adjuvants2011

    • Author(s)
      T.Kaisho
    • Organizer
      IVI seminar
    • Place of Presentation
      International Vaccine Institute(韓国)
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] 核酸系免疫アジュバントに対する樹状細胞サブセットの応答機構2011

    • Author(s)
      改正恒康
    • Organizer
      第29回日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      大分
    • Year and Date
      2011-02-10
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] Dendritic cell sensing and responses for nucleic acid adjuvants.2011

    • Author(s)
      T. Kaisho
    • Organizer
      KSBMB 2011 Annual Meeting
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] 樹状細胞サブセット機能を制御する分子機構2011

    • Author(s)
      改正恒
    • Organizer
      鳥取大学生命科学科講義
    • Place of Presentation
      米子
    • Year and Date
      2011-12-07
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Double-stranded RNA of lactic acid bacteria triggers TLR3-mediated IFN-・production by dendritic cells.2011

    • Author(s)
      T. Kawashima, H. Yan, Z. Guo, R. Uchiyama, J. Carreras, T. Kaisho, O. Takeuchi, S. Akira, H. Tsutsui, T. Saito, I. Nishimura, N. Tsuji
    • Organizer
      第40回日本免疫学会総会・学術集会記録 40:121, 2011
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] 樹状細胞機能制御の分子基盤2011

    • Author(s)
      改正恒
    • Organizer
      免疫サマースクール
    • Place of Presentation
      宮城
    • Year and Date
      2011-08-01
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] HSP70 is essential for PDLIM2-mediated termination of NF-・B signaling.2011

    • Author(s)
      T. Tanaka, T. Kaisho.
    • Organizer
      第40回日本免疫学会総会・学術集会記録 40:36, 2011
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] 核酸系免疫アジュバントに対する樹状細胞サブセットの応答機構2011

    • Author(s)
      改正恒康
    • Organizer
      第29回日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      大分
    • Year and Date
      2011-02-10
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] ケモカイン受容体Xcrl発現樹状細胞のin vivo における機能的意義/Critical roles of murine XC chemokine receptor 1-expressing DC subset in viv2011

    • Author(s)
      6.C. Yamazaki, H. Hemmi, R. Miyamoto, I. Sasaki, T. Ito, K. Hoshino, T. Kaisho
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Dendritic cell sensing and responses for nucleic acid adjuvants2011

    • Author(s)
      T.Kaisho
    • Organizer
      KSBMB
    • Place of Presentation
      COEX, Inter Continental Seoul(韓国)(招待講演)
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] ケモカイン受容体 Xcrl 発現樹状細胞の in vivo における機能的意義2011

    • Author(s)
      C. Yamazaki, H. Hemmi, R. Miyamoto, I. Sasaki, T. Ito, K. Hoshino, T. Kaisho
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] HSP70はPDLIMによるNF-Bシグナルの負の制御に必須である/ HSP70 is essential for PDLIM2-mediated termination of NF-κB signaling2011

    • Author(s)
      田中貴志、改正恒康
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] PDLIM4によるSTATシグナルの負の制御機構/PDLIM4 negatively regulates STAT signaling by recruiting protein tyrosine phosphatases2011

    • Author(s)
      平島健志、改正恒康、田中貴志
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] BDCA3+DC の発現するケモカインレセプター XCR1 と NK 細胞活性化能の解析2011

    • Author(s)
      伊藤量基, 宮本理恵, 山崎千尋, 星野克明, 改正恒康, 野村昌作
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Crucial role of plasmacytoid dendritic cells in the regulation of inflammation and T Cell immunity in vivo.2011

    • Author(s)
      H. Takagi, T. Fukaya, Y. Sato, K. Sato, A. Shibazaki, A. Hijikata, O. Ohara, T Kaisho, B. Malissen, K. Sato.
    • Organizer
      第40回日本免疫学会総会・学術集会記録40:118, 2011
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] TLR3を介した乳酸菌2本鎖RNAのIFN-β産生誘導/Double-stranded RNA of lactic acid bacteria triggers TLR3-mediated IFN- production by dendritic cells2011

    • Author(s)
      7.T. Kawashima, H. Yan, Z. Guo, R. Uchiyama, J. Carreras, T. Kaisho, O. Takeuchi, S. Akira, H. Tsutsui, T. Saito, I. Nishimura, N. Tsuji
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] B. Malissen. Critical role of siglec-H in the function of plasmacytoid dendritic cells for the regulation of inflammation and T Cell immunity in vivo2011

    • Author(s)
      K. Sato, H. Takagi, T. Fukaya, Y. Sato, K. Sato, A. Shibazaki, A. Hijikata, O. Ohara, T Kaisho
    • Organizer
      第40回日本免疫学会総会・学術集会記録 40:118, 2011
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Dendritic cell sensing and responses for nucleic acid adjuvants.2011

    • Author(s)
      T. Kaisho
    • Organizer
      KSBMB(招待講演)
    • Place of Presentation
      COEX intercontinental Seoul(Korea)
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Dendritic cell sensing and responses for nucleic acid adjuvants2011

    • Author(s)
      T.Kaisho
    • Organizer
      IVI seminar
    • Place of Presentation
      International Vaccine Institute(韓国)
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] ショートトーク自然免疫~感染の検知システム2011

    • Author(s)
      改正恒
    • Organizer
      免疫ふしぎ未来
    • Place of Presentation
      東京
    • Year and Date
      2011-08-21
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] 核酸系免疫アジュバントに対する樹状細胞サブセットの応答機構2011

    • Author(s)
      改正恒康
    • Organizer
      第29回日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      大分
    • Year and Date
      2011-02-10
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Dendritic cell sensing and responses for nucleic acid adjuvants2011

    • Author(s)
      T.Kaisho
    • Organizer
      KSBMB
    • Place of Presentation
      COEX, Inter Continental Seoul(韓国)(招待講演)
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Critical roles of murine XC chemokine receptor 1-expressing DC subset in vivo.2011

    • Author(s)
      C. Yamazaki, H. Hemmi, R. Miyamoto, I. Sasaki, T. Ito, K. Hoshino, T. Kaisho
    • Organizer
      第40回日本免疫学会総会・学術集会記録 40:119, 2011
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] 樹状細胞機能制御の分子基盤2011

    • Author(s)
      改正恒康
    • Organizer
      免疫サマースクール
    • Place of Presentation
      ラフォーレ蔵王(宮城県)
    • Year and Date
      2011-08-01
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 自然免疫~感染の検知システム2011

    • Author(s)
      改正恒康
    • Organizer
      免疫ふしぎ未来
    • Place of Presentation
      日本科学未来館(東京)
    • Year and Date
      2011-08-21
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Evaluation of SCAT1: a genetically-encoded probe for detecting activation of caspase-1 in living cells.2011

    • Author(s)
      K. Shikada, Y. Yamaguchi, T. Liu, K. Takemoto, K. Hoshino, T. Kaisho. E. Kuranaga, M. Miura.
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] TLR3を介した乳酸菌2本鎖RNA の IFN-β産生誘導/Double-stranded RNA of lactic acid bacteria triggers TLR3 -mediated IFN-ɤ production by dendritic cells2011

    • Author(s)
      T. Kawashima, H. Yan, Z. Guo, R. Uchiyama, J. Carreras, T. Kaisho , O. Takeuchi, S. Akira, H. Tsutsui, T. Saito, I. Nishimura, N. Tsuji
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] HSP70 は PDLIM による NF-κB シグナルの負の制御に必須である2011

    • Author(s)
      田中貴志, 改正恒康
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] Dendritic cell sensing and responses for nucleic acid adjuvants2011

    • Author(s)
      T. Kaisho.
    • Organizer
      IVI seminar
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-05-17
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Evaluation of SCAT1 : a genetically-encoded probe for detecting activation of caspase-1 in living cells2011

    • Author(s)
      K. Shikada, Y. Yamaguchi, T. Liu, K. Takemoto, K. Hoshino, T. Kaisho . E. Kuranaga, M. Miura
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23390124
  • [Presentation] BDCA3+DCの発現するケモカインレセプターXCR1とNK細胞活性化能の解析/ Importance of chemokines system between human BDCA3+ dendritic cells and NK cells in innate cytotoxic response.2011

    • Author(s)
      T. Ito, R. Miyamoto, C. Yamazaki, K. Hoshino, T. Kaisho
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] 樹状細胞機能を制御する分子基盤-マウスからヒトへ-2010

    • Author(s)
      改正恒康
    • Organizer
      林原生物化学研究所セミナー
    • Place of Presentation
      岡山
    • Year and Date
      2010-07-09
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 核酸アジュバントによる樹状細胞サブセット活性化を制御する分子機構-マウスからヒトへ-2010

    • Author(s)
      改正恒康
    • Organizer
      北海道大学院薬学研究院大学院特別講義
    • Place of Presentation
      札幌
    • Year and Date
      2010-11-09
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Dendritic cell subsets in inflammation.2010

    • Author(s)
      T. Kaisho
    • Organizer
      The 12th Biennial International Endotoxin & Innate Immunity Society (IEIIS) Meeting
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] Inhibitor of IkB kinase activity, BAY11-7082, interferes with the IRF7 nuclear translocation and type I IFN production by plasmacytoid dendritic cells2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 11th International Symposium on Dendritic Cells, DC2010
    • Place of Presentation
      Lugano, Switzerland
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 樹状細胞機能を制御する分子基盤-マウスからヒトへ-2010

    • Author(s)
      改正恒康
    • Organizer
      林原生物化学研究所セミナー
    • Place of Presentation
      岡山
    • Year and Date
      2010-07-09
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 遺伝子改変マウスによる樹状細胞機能制御機構の解明2010

    • Author(s)
      改正恒康
    • Organizer
      第53回未来医療セミナー
    • Place of Presentation
      大阪大学(大阪)
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] How dendritic cells respond to nucleic acid adjivants2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 9th International Veterinary Immunology Symposium
    • Place of Presentation
      東京
    • Year and Date
      2010-08-17
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 樹状細胞機能を制御する分子基盤-マウスからヒトへ-2010

    • Author(s)
      改正恒康
    • Organizer
      林原生物化学研究所セミナー
    • Place of Presentation
      岡山
    • Year and Date
      2010-07-09
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] Critical role of DOCK2 in type I IFN induction in plasmacytoid dendritic cells2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan(Oral presentation)
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸アジュバントによる樹状細胞活性化の分子メカニズム2010

    • Author(s)
      改正恒康
    • Organizer
      ワクチンフォーラム2010
    • Place of Presentation
      東京
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 遺伝子改変マウスによる樹状細胞機能制御機構の解明2010

    • Author(s)
      改正恒康
    • Organizer
      第53回未来医療セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Molecular mechanisms for Dendritic cell responses against nucleic acid adjuvants2010

    • Author(s)
      T.Kaisho
    • Organizer
      LIAI-RCAI Joint Workshop
    • Place of Presentation
      横浜
    • Year and Date
      2010-11-12
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] 核酸アジュバントによる樹状細胞活性化の分子メカニズム2010

    • Author(s)
      改正恒康
    • Organizer
      ワクチンフォーラム2010
    • Place of Presentation
      東京
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Conservation of a chemokine system, XCRI and its ligand, XCL1, between human and mice2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 11th International Symposium on Dendritic Cells, DC2010
    • Place of Presentation
      Lugano, Switzerland
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 1分子顕微鏡によるNFKB分解誘導の時空間制御機構解明2010

    • Author(s)
      T.Kaisho
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学川内キャンパス
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 樹状細胞サブセット機能を制御する分子機構2010

    • Author(s)
      改正恒康
    • Organizer
      第60回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-25
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Lactic acid bacteria induce Toll-like receptor 3-mediated IFN-beta production by dendritic cells in vitro and in vivo2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan(Oral presentation)
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸に対する樹状細胞応答の制御機構2010

    • Author(s)
      改正恒康
    • Organizer
      新学術領域「自然炎症」第1回公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-01-13
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] How dendritic cells sense and respond to nucleic acid adjuvants2010

    • Author(s)
      T.Kaisho
    • Organizer
      RCAI International Summer Program 2010
    • Place of Presentation
      横浜
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Molecular mechanisms for Dendritic cell responses against nucleic acid adjuvants2010

    • Author(s)
      T.Kaisho
    • Organizer
      LIAI-RCAI Joint Workshop
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2010-11-12
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸アジュバントによる樹状細胞サブセット活性化を制御する分子機構-マウスからヒトへ-2010

    • Author(s)
      改正恒康
    • Organizer
      北海道大学院薬学研究院大学院特別講義
    • Place of Presentation
      札幌
    • Year and Date
      2010-11-09
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] 樹状細胞サブセット機能を制御する分子機構2010

    • Author(s)
      改正恒康
    • Organizer
      第60回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-25
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Molecular mechanisms for dendritic cell heterogeneity2010

    • Author(s)
      T.Kaisho
    • Organizer
      NZ-RIKEN-CHIBA Joint Workshop
    • Place of Presentation
      横浜
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 核酸に対する樹状細胞応答の制御機構2010

    • Author(s)
      改正恒康
    • Organizer
      新学術領域「自然炎症」第1回公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-01-13
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸アジュバントによる樹状細胞サブセット活性化を制御する分子機構-マウスからヒトへ-2010

    • Author(s)
      改正恒康
    • Organizer
      北海道大学院薬学研究院大学院特別講義
    • Place of Presentation
      札幌
    • Year and Date
      2010-11-09
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 核酸に対する樹状細胞応答の制御機構2010

    • Author(s)
      改正恒康
    • Organizer
      新学術領域「自然炎症」第1回公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-01-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 核酸アジュバントによる樹状細胞活性化の分子メカニズム2010

    • Author(s)
      改正恒康
    • Organizer
      ワクチンフォーラム2010
    • Place of Presentation
      東京
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] Critical roles of an Ets family member, Spi-B, in pDC maturation2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan(Oral presentation)
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] How dendritic cells respond to nucleic acid adjivants2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 9th International Veterinary Immunology Symposium
    • Place of Presentation
      東京
    • Year and Date
      2010-08-17
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] How dendritic cells respond to nucleic acid adjivants2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 9th International Veterinary Immunology Symposium(16-20)
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2010-08-17
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸アジュバントによる樹状細胞サブセット活性化を制御する分子機構2010

    • Author(s)
      改正恒康
    • Organizer
      マウスからヒトへ.大学院特別講義
    • Place of Presentation
      北海道大学院薬学研究院(札幌)
    • Year and Date
      2010-11-09
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Statins, inhibitors of HMG-CoA reductase, function as inhibitors for cellular and molecular components involved in type I IFN production2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 11th International Symposium on Dendritic Cells, DC2010
    • Place of Presentation
      Lugano, Switzerland
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] How dendritic cells sense and respond to nucleic acid adjuvants2010

    • Author(s)
      T.Kaisho
    • Organizer
      RCAI International Summer Program 2010
    • Place of Presentation
      横浜
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸アジュバントによる樹状細胞活性化の分子メカニズム2010

    • Author(s)
      改正恒康
    • Organizer
      ワクチンフォーラム2010
    • Place of Presentation
      新宿明治生命安田ホール(東京)
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Molecular mechanisms for Dendritic cell responses against nucleic acid adjuvants2010

    • Author(s)
      T.Kaisho
    • Organizer
      LIAI-RCAI Joint Workshop
    • Place of Presentation
      横浜
    • Year and Date
      2010-11-12
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 遺伝子改変マウスによる樹状細胞機能制御機構の解明2010

    • Author(s)
      改正恒康
    • Organizer
      第53回未来医療セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Molecular mechanisms for Dendritic cell responses against nucleic acid adjuvants2010

    • Author(s)
      T.Kaisho
    • Organizer
      LIAI-RCAI Joint Workshop
    • Place of Presentation
      横浜
    • Year and Date
      2010-11-12
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 遺伝子改変マウスによる樹状細胞機能制御機構の解明2010

    • Author(s)
      改正恒康
    • Organizer
      第53回未来医療セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] How dendritic cells sense and respond to nucleic acid adjuvants2010

    • Author(s)
      T.Kaisho
    • Organizer
      RCAI International Summer Program 2010
    • Place of Presentation
      横浜
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] Molecular mechanisms for dendritic cell heterogeneity2010

    • Author(s)
      T.Kaisho
    • Organizer
      NZ-RIKEN-CHIBA Joint Workshop
    • Place of Presentation
      横浜
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] 樹状細胞サブセット機能を制御する分子機構第60回日本アレルギー2010

    • Author(s)
      改正恒康
    • Organizer
      学会秋季学術大会(特別講演)
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2010-11-25
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 樹状細胞サブセット機能を制御する分子機構2010

    • Author(s)
      改正恒康
    • Organizer
      第60回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-25
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] PDLIM2 regulates Th17-mediated responses through degradation of STAT3 transcription factor2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan(Oral presentation)
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Molecular mechanisms for dendritic cell heterogeneity2010

    • Author(s)
      T.Kaisho
    • Organizer
      NZ-RIKEN-CHIBA Joint Workshop
    • Place of Presentation
      横浜
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] How dendritic cells respond to nucleic acid adjivants2010

    • Author(s)
      T.Kaisho
    • Organizer
      The 9th International Veterinary Immunology Symposium
    • Place of Presentation
      東京
    • Year and Date
      2010-08-17
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] The role of M cells in intestinal immunity.2010

    • Author(s)
      T. Kanaya, K. Hase, G. Nakato, T. Kaisho, I. R. Williams, H. Ohno
    • Organizer
      The 12th Biennial International Endotoxin & Innate Immunity Society (IEIIS) Meeting
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-23659245
  • [Presentation] An Ets family member, Spi-B, transactivates type I interferon promoters through the cooperation with IRF-72010

    • Author(s)
      T.Kaisho
    • Organizer
      The 14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan(Oral presentation)
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Molecular mechanisms for dendritic cell heterogeneity2010

    • Author(s)
      T.Kaisho
    • Organizer
      NZ-RIKEN-CHIBA Joint Workshop
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸成分による樹状細胞からのI型インターフェロン産生機構とその病理的意義2009

    • Author(s)
      改正恒康
    • Organizer
      第37回日本臨床免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-13
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸成分による樹状細胞からのI型インターフェロン産生機構とその病理的意義2009

    • Author(s)
      改正恒康
    • Organizer
      第37回日本臨床免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] 自然免疫による疾患制御:核酸系免疫アジュバントによる樹状細胞活性化機構2009

    • Author(s)
      改正恒康
    • Organizer
      第21回日本アレルギー学会春季臨床大会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-21022048
  • [Presentation] 自然免疫による疾患制御:核酸系免疫アジュバントによる樹状細胞活性化機構2009

    • Author(s)
      改正恒康
    • Organizer
      第21回日本アレルギー学会春季臨床大会
    • Place of Presentation
      岐阜
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 形質細胞様樹状細胞のワクチン開発における意義2009

    • Author(s)
      改正恒康
    • Organizer
      第13回日本ワクチン学会
    • Place of Presentation
      札幌
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] 核酸成分による樹状細胞からのI型インターフェロン産生機構とその病理的意義2009

    • Author(s)
      改正恒康
    • Organizer
      第37回日本臨床免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-13
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] 乳酸菌は樹状細胞エンドソーム内TLRを介してIFN-βを誘導する2009

    • Author(s)
      T.Kawashima, R.Uchiyama, H.Tsutsui,(閻会敏Dong-Ju You or Myoung Ho Jang), T.Kaisho, T.Saito, I.Nishimura, N.Tsuji
    • Organizer
      第39回日本免疫学会総会・学術集会記録39,181,2009
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 形質細胞様樹状細胞のワクチン開発における意義2009

    • Author(s)
      改正恒康
    • Organizer
      第13回日本ワクチン学会
    • Place of Presentation
      札幌
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Spi-B is critical fpr plasmacytoid dendritic cell development and function2009

    • Author(s)
      T.Kaisho
    • Organizer
      Keystone Symposia on Molecular and Cellular Biology
    • Place of Presentation
      Keystone, Banff, Alberta, Canada
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] TRAF6 is required for generation of the B-la B cell compartment as well as T cell-dependent and -independent humoral immune responses2009

    • Author(s)
      T.Kaisho
    • Organizer
      The First International Kishimoto Foundation Symposium. Immune Regulation : Present and Future
    • Place of Presentation
      Osaka, Japan
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 自然免疫による疾患制御:核酸系免疫アジュバントによる樹状細胞活性化機構2009

    • Author(s)
      改正恒康
    • Organizer
      第21回日本アレルギー学会春季臨床大会
    • Place of Presentation
      長良川
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] PDHM2はTh17細胞分化を負に制御する2009

    • Author(s)
      T.Tanaka, T.Matsuda, T.Kaisho
    • Organizer
      第39回日本免疫学会総会・学術集会記録39,69,2009
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 形質細胞様樹状細胞のワクチン開発における意義2009

    • Author(s)
      改正恒康
    • Organizer
      第13回日本ワクチン学会
    • Place of Presentation
      札幌
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 自然免疫による疾患制御:核酸系免疫アジュバントによる樹状細胞活性化機構2009

    • Author(s)
      改正恒康
    • Organizer
      第21回日本アレルギー学会春季臨床大会
    • Place of Presentation
      岐阜
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-21659123
  • [Presentation] 形質細胞様樹状細胞機能における転写因子Spi-Bの役割2009

    • Author(s)
      I.Sasaki, K.Hoshino, T.Kaisho
    • Organizer
      第39回日本免疫学会総会・学術集会記録39,110,2009
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 自然免疫による疾患制御:核酸系免疫アジュバントによる樹状細胞活性化機構2009

    • Author(s)
      改正恒康
    • Organizer
      第21回日本アレルギー学会春季臨床大会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Presentation] Training course 2(Immunology)2008

    • Author(s)
      改正恒康
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-07
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] ユビキチンE3リガーゼPDLIM2によるTGF-βシグナル伝達の制御2008

    • Author(s)
      T.Kaisho
    • Organizer
      第38回日本免疫学会総会・学術集会記録38,217,2008
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 2本鎖RNApolyAUは主にTLR3を介してCD8陽性T細胞応答を誘導する2008

    • Author(s)
      T.Kaisho
    • Organizer
      第38回日本免疫学会総会・学術集会記録38,120,2008
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 核酸系免疫アジュバントに対する樹状細胞応答機構2008

    • Author(s)
      改正恒康
    • Organizer
      Dendritic cell responses against nucleic acid adjuvants)第3回生態適応セミナー(第5回細胞認識応答学セミナー)
    • Place of Presentation
      東北大学大学院生命科学研究科
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] PDLIM2 and HSP70 cooperatively terminate Toll-like receptor-mediated NF-KB activation2008

    • Author(s)
      T.Tanaka, T.Kaisho
    • Organizer
      The 10th International Symposium on Dendritic Cells, DC2008
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Training course 22008

    • Author(s)
      改正恒康
    • Organizer
      The Awaji International Forum on Infection and Immunity(Immunology)
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-07
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Presentation] Molecular mechanism of type I interferon production from plasmacytoid dendritic cell2008

    • Author(s)
      改正恒康
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-09
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] PDC-TREM, a new plasmacytoid dendritic cell receptor, is responsible for augmentation of type I interferon production2008

    • Author(s)
      T.Kaisho
    • Organizer
      The 10th International Symposium on Dendritic Cells, DC2008
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Molecular mechanism of type I interferon production from plasmacytoid dendritic cell2008

    • Author(s)
      改正恒康
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-07
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Presentation] Critical roles of IKKa in dendritic cell subsets2008

    • Author(s)
      T.Kaisho
    • Organizer
      The 10th International Symposium on Dendritic Cells, DC2008
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Critical roles of IKKa in dendritic cell subsets2008

    • Author(s)
      改正恒康
    • Organizer
      The 10th International Symposium on Dendritic Cells, DC 2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-10-05
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Presentation] 樹状細胞による免疫機能制御2008

    • Author(s)
      改正恒康
    • Organizer
      大学院特別講義
    • Place of Presentation
      北海道大学院薬学研究院(札幌)
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 共生細菌によるTLR3依存的なIFN-β産生とTh1免疫応答2008

    • Author(s)
      T.Kaisho
    • Organizer
      第38回日本免疫学会総会・学術集会記録38,122,2008
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Critical roles of IKKa in dendritic cell subsets2008

    • Author(s)
      改正恒康
    • Organizer
      The 10th International Symposium on Dendritic Cells, DC2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-10-05
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Presentation] Training course 2 (Immunology)2008

    • Author(s)
      T.Kaisho
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Island, Hyogo, Japan
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Critical roles of IKKα in dendritic cell subsets2008

    • Author(s)
      改正恒康
    • Organizer
      The 10th International Symposium on Dendritic Cells, DC2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-10-05
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Cholera toxin can induce arginase I gene expression in plasmacytoid dendritic cell2008

    • Author(s)
      I.Sasaki, K.Hoshino, T.Kaisho
    • Organizer
      第38回日本免疫学会総会・学術集会記録38,205,2008
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 自己免疫疾患における核酸系免疫アジュバント刺激樹状細胞の意義2008

    • Author(s)
      改正恒康
    • Organizer
      第52回日本リウマチ学会総会・学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2008-04-23
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Molecular mechanism of type I interferon production from plasmacytoid dendritic cell2008

    • Author(s)
      T.Kaisho
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji Island, Hyogo, Japan
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Cholera toxin can induce arginase I gene expression in plasmacytoid dendritic cell2008

    • Author(s)
      T.Kaisho
    • Organizer
      The 10th International Symposium on Dendritic Cells, DC2008
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] 自己免疫疾患における核酸系免疫アジュバント刺激樹状細胞の意義2008

    • Author(s)
      改正恒康
    • Organizer
      第52回日本リウマチ学会総会・学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2008-04-23
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Presentation] Molecular mechanism of type I interferon production from plasmacytoid dendritic cell2008

    • Author(s)
      改正恒康
    • Organizer
      The Awaji International Forum on Infection and Immunitv
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-09
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Presentation] Training course 2(Immunology)2008

    • Author(s)
      改正恒康
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-07
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Presentation] 自己免疫疾患における核酸系免疫アジュバント刺激樹状細胞の意義2008

    • Author(s)
      改正恒康
    • Organizer
      第52回日本リウマチ学会総会・学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2008-04-23
    • Data Source
      KAKENHI-PROJECT-20060033
  • [Presentation] 核酸系免疫アジュバントによる樹状細胞活性化とアレルギー制御2008

    • Author(s)
      改正恒康
    • Organizer
      第11回Forum on Allergy in Nagoya
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] PDLIM2欠損マウスにおける皮膚創傷治癒反応の充進2008

    • Author(s)
      T.Tanaka, T.Kaisho
    • Organizer
      第38回日本免疫学会総会・学術集会記録38,148,2008
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-20390146
  • [Presentation] Dendritic cell function regulated by nucleic acid adjuvants.2008

    • Author(s)
      T. Kaisho
    • Organizer
      RIKEN-INSERM/Pasteur Joint Symposium
    • Place of Presentation
      Auffargis, France
    • Year and Date
      2008-03-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Critical involvement of IkB kinase-αin TLR7/9-induced type I IFN production.2007

    • Author(s)
      T. Kaisho
    • Organizer
      Keystone Symposia, Intracellular and Intercellular Signaling in Dendritic Cell Function
    • Place of Presentation
      Colorado, USA
    • Year and Date
      2007-02-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] IκB Kinase-α as a Critical Regulator for Dendritic Cell Function2007

    • Author(s)
      T. Kaisho
    • Organizer
      The 20th Naito Conference "Innate Immunity in medicine and Biology [III]".
    • Place of Presentation
      Shonan, Japan
    • Year and Date
      2007-10-10
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] 樹状細胞におけるIKKαの機能的意義2007

    • Author(s)
      改正 恒康
    • Organizer
      第28回日本炎症・再生医学会
    • Place of Presentation
      東京
    • Year and Date
      2007-08-02
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Presentation] Critical involvement of IκB kinase-α in TLR7/9-induced type I IFN production.2007

    • Author(s)
      T. Kaisho
    • Organizer
      Keystone Symposia, Intracellular and Intercellular Signaling in Dendritic Cell Function
    • Place of Presentation
      Colorado, USA
    • Year and Date
      2007-02-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] 樹状細胞におけるIKKαの機能的意義2007

    • Author(s)
      改正 恒康
    • Organizer
      第28回日本炎症・再生医学会
    • Place of Presentation
      東京
    • Year and Date
      2007-08-02
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Immunological phenotype of pattern recognition receptor defects-from knockout mice to human immune disorders.2007

    • Author(s)
      T. Kaisho
    • Organizer
      The 2nd RCAI-JSI Workshop
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2007-05-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Immunological phenotype of pattern recognition receptor defects-from knockout mice to human immune disorders2007

    • Author(s)
      改正 恒康
    • Organizer
      The 2nd RCAI-JSI Workshop
    • Place of Presentation
      横浜
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Presentation] Immunological phenotype of pattern recognition receptor defects…from knockout mice to human immune disorders2007

    • Author(s)
      改正 恒康
    • Organizer
      The 2^<nd>RCAI-JSI Workshop
    • Place of Presentation
      横浜
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] IkB Kinase-αas a Critical Regulator for Dendritic Cell Function.2007

    • Author(s)
      T. Kaisho
    • Organizer
      The 20th Naito Conference Innate Immunity in medicine and Biology [III]
    • Place of Presentation
      Shonan, Japan
    • Year and Date
      2007-10-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] IκB Kinase-α as a Critical Regulator for Dendritic Cell Function2007

    • Author(s)
      T. Kaisho
    • Organizer
      The 20th Naito Conference "Innate Immunity in medicine and Biology [III]"
    • Place of Presentation
      神奈川
    • Year and Date
      2007-10-10
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Presentation] Immunological phentype of pattern recognition receptor defects … from knockout mice to human immune disorders.2007

    • Author(s)
      T. Kaisho
    • Organizer
      The 2nd RCAI-JSI Workshop
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2007-05-25
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] IκB Kinase-α as a Critical Regulator for Dendritic Cell Function2007

    • Author(s)
      T. Kaisho
    • Organizer
      The 20^<th>Naito Conference"Innate Immunity in medicine and Biology[III]"
    • Place of Presentation
      神奈川
    • Year and Date
      2007-10-10
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Regulation of Innate Immunity.2007

    • Author(s)
      T. Kaisho
    • Organizer
      The 5th EAASCI-GA3LEN-Davos Meeting
    • Place of Presentation
      Davos, Swizzerland
    • Year and Date
      2007-02-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Type I interferon induction mechanism in dendritic cells.2007

    • Author(s)
      T. Kaisho
    • Organizer
      RCAI-MPI Joint Workshop
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2007-04-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Type I interferon induction mechanism in dendritic cells2007

    • Author(s)
      T. Kaisho
    • Organizer
      RCAI-MPI Joint Workshop
    • Place of Presentation
      ドイツ(ベルリン)
    • Year and Date
      2007-04-16
    • Data Source
      KAKENHI-PROJECT-19041070
  • [Presentation] Type I interferon induction mechanism in dendritic cells2007

    • Author(s)
      T. Kaisho
    • Organizer
      RCAI-MPI Joint Workshop
    • Place of Presentation
      ドイツ(ベルリン)
    • Year and Date
      2007-04-16
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Regulation of Innate Immunity.2007

    • Author(s)
      T. Kaisho
    • Organizer
      The 5th EAACI-GA2LEN-Davos Meeting
    • Place of Presentation
      Davos, Swizzerland
    • Year and Date
      2007-02-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Critical roles of IkB kinase-α in TLR7/9-induced type IIFN production.2006

    • Author(s)
      T. Kaisho
    • Organizer
      RCAI-JSI International Symposium on Immunology 2006
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Critical of IKKαin TLR7/9-stimulated DC.2006

    • Author(s)
      T. Kaisho
    • Organizer
      The 36th annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2006-12-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Critical roles of IκB kinase-α in TLR7/9-induced type I IFN production.2006

    • Author(s)
      T. Kaisho
    • Organizer
      RCAI-JSI International Symposium on Immunology 2006
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2006-06-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] Critical roles of IKKα in TLR7/9-stimulated DC.2006

    • Author(s)
      T. Kaisho
    • Organizer
      The 36th Annual Meeting of the Japanese Society for Immunology
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2006-12-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590483
  • [Presentation] In vivo roles of dendritic cells expressing a chemokine receptor, XCR1.

    • Author(s)
      T. Kaisho.
    • Organizer
      France-Japan Joint Forum “Frontiers in Innate Immunity''
    • Place of Presentation
      Strasbourg(France)
    • Year and Date
      2013-06-05 – 2013-06-08
    • Invited
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Long-term memory T cell response induced by adjuvant role of iNKT cells.

    • Author(s)
      K. Shimizu, Y. Sato, J. Shinga, M. Asakura, T. Kaisho.
    • Organizer
      第42回日本免疫学会総会;学術集会記録42:163, 2013
    • Place of Presentation
      幕張メッセ(千葉県、千葉市)
    • Year and Date
      2013-12-11 – 2013-12-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] In vivo roles of XC chemokine receptor 1-expressing dendritic cells.

    • Author(s)
      T. Ohta, H. Hemmi, C. Yamazaki, M. Sugiyama, I. Sasaki, K. Hoshino, T. Kaisho.
    • Organizer
      The 15th International Congress of Immunology
    • Place of Presentation
      Milan(Italy)
    • Year and Date
      2013-08-22 – 2013-08-27
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Roles of ArginaseⅠ in Cholera toxin-induced production of proinflammatory cytokines.

    • Author(s)
      I. Sasaki, S. Fukuda, T. Orimo, H. Hemmi, T. Kaisho.
    • Organizer
      第43回日本免疫学会総会;学術集会記録43:99, 2014
    • Place of Presentation
      京都国際会館(京都府、京都市)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] A novel mechanism to generate the intestinal intraepithelial T lymphocytes by XCR-expressing dendric cells.

    • Author(s)
      T. Ohta, H. Hemmi, C. Yamazaki, M. Sugiyama, I. Sasaki, K. Hoshino, T. Kaisho.
    • Organizer
      第42回日本免疫学会総会;学術集会記録42:124, 2013
    • Place of Presentation
      幕張メッセ(千葉県、千葉市)
    • Year and Date
      2013-12-11 – 2013-12-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] In vivo roles of XCR1-expressing dendritic cells.

    • Author(s)
      T.Kaisho
    • Organizer
      The 42th Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      幕張メッセ(千葉県、千葉市)
    • Year and Date
      2013-12-11 – 2013-12-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Critical in vivo roles of dendritic cells expressing a chemokine receptor, XCR1.

    • Author(s)
      T.Kaisho
    • Organizer
      The 2013 Fall Conference of the Korean Association of Immunologists
    • Place of Presentation
      Seoul(Korea)
    • Year and Date
      2013-11-07 – 2013-11-08
    • Invited
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Critical roles of dendritic cells expressing a chemokine receptor XCR1.

    • Author(s)
      T. Kaisho, H. Hemmi, M. Sugiyama, T. Ohta.
    • Organizer
      The Joint international Meeting of The 78th Meeting of the Japanese Society of Interferon and Cytokine Research and The 21st International Symposium on Molecular Cell Biology of Macrophage
    • Place of Presentation
      都市センターホテル(東京都、千代田区)
    • Year and Date
      2013-05-20 – 2013-05-21
    • Invited
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] The transcription factor IRF8 is required for basophil development.

    • Author(s)
      H. Sasaki, D. Kurotaki, N. Osato, I. Sasaki, C. Kaneda, A. Nishiyama, T.Kaisho, H. C. III. Morse, K. Ozato, T. Tamura.
    • Organizer
      第42回日本免疫学会総会;学術集会記録42:80, 2013
    • Place of Presentation
      幕張メッセ(千葉県、千葉市)
    • Year and Date
      2013-12-11 – 2013-12-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] The role of M cells in intestinal helminthic infection.

    • Author(s)
      C. Shimokawa, T. Kanaya, T. Kaisho.
    • Organizer
      第42回日本免疫学会総会;学術集会記録42:211, 2013
    • Place of Presentation
      幕張メッセ(千葉県、千葉市)
    • Year and Date
      2013-12-11 – 2013-12-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] XCL1 and XCR1 are involved in intestinal immne homeostasis by dendritic cells.

    • Author(s)
      1T. Ohta, S. Okura, H. Hemmi, M. Sugiyama, I. Sasaki, C. Yamazaki, K. Hoshino, T. Kaisho.
    • Organizer
      第43回日本免疫学会総会;学術集会記録43:203, 2014
    • Place of Presentation
      京都国際会館(京都府、京都市)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Enhanced apoptosis by disruption of the STAT3-IκBζ signaling pathway in epithelial cells induces Sjoegren”s syndrome-like autoimmune diseases.

    • Author(s)
      A. Okuma, K. Hoshino, T. Kaisho, T. Muta.
    • Organizer
      The 15th International Congress of Immunology
    • Place of Presentation
      Milan(Italy)
    • Year and Date
      2013-08-22 – 2013-08-27
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] IL-27 affects helper T cell response via regulation of PGE2 production by macrophages.

    • Author(s)
      Y. Sato, H. Hara, S. Suzuki, T. Kaisho and H. Yoshida.
    • Organizer
      The Joint international Meeting of The 78th Meeting of the Japanese Society of Interferon and Cytokine Research and The 21st International Symposium on Molecular Cell Biology of Macrophage
    • Place of Presentation
      都市センターホテル(東京都、千代田区)
    • Year and Date
      2013-05-20 – 2013-05-21
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Homeostasis of thymus-derived Foxp3+ regulatory T cells is controlled by ultraviolet B exposure in the skin.

    • Author(s)
      S. Yamazaki, A. Nishioka, T. Kaisho, O. Taguchi, S. Sakaguchi, A.Morita.
    • Organizer
      第43回日本免疫学会総会;学術集会記録43:176, 2014
    • Place of Presentation
      京都国際会館(京都府、京都市)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Resistance to a helminthic infection is dependent on mast cell activation mediated by ATP in Spi-B-deficient mice.

    • Author(s)
      C. Shimokawa, T. Kanaya, K. Ishiwata, Y. Kurashima, H. Kiyono, T. Kaisho, H. Ohno.
    • Organizer
      第43回日本免疫学会総会;学術集会記録43:213, 2014
    • Place of Presentation
      京都国際会館(京都府、京都市)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective IFN-β.

    • Author(s)
      T. Kawashima, H Yan, Z. Guo, J. Carreras, R. Uchiyama, R. Fukui, T. Kaisho, S. Akira, K. Miyake, H. Tsutsui, T. Saito, N.M.Tsuji.
    • Organizer
      第42回日本免疫学会総会;学術集会記録42:123, 2013
    • Place of Presentation
      幕張メッセ(千葉県、千葉市)
    • Year and Date
      2013-12-11 – 2013-12-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Lactococcus lactis subsp. cremoris FC triggers IFN -γ production from NK and T cells via IL-12 and IL-18.

    • Author(s)
      Kosaka, H. Yan, H. Tsutsui, T. Kaisho, N. Tsuji.
    • Organizer
      第42回日本免疫学会総会;学術集会記録42:165, 2013
    • Place of Presentation
      幕張メッセ(千葉県、千葉市)
    • Year and Date
      2013-12-11 – 2013-12-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • [Presentation] Function of XCR1-expressing dendric cells in oral tolerance.

    • Author(s)
      H. Hemmi, M. Sugiyama, T. Ohta, I. Sasaki, C. Yamazaki, T. Tanaka, K. Hoshino, T. Kaisho.
    • Organizer
      第42回日本免疫学会総会;学術集会記録42:163, 2013
    • Place of Presentation
      幕張メッセ(千葉県、千葉市)
    • Year and Date
      2013-12-11 – 2013-12-13
    • Data Source
      KAKENHI-PLANNED-21117003
  • 1.  HOSHINO Katsuaki (50324843)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 9 results
  • 2.  HIRANO Toshio (40136718)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  MATSUDA Tadashi (20212219)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  TANAKA Takashi (00415225)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 5.  SHIZUO Akira (50192919)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  TAKEDA Kiyoshi (20309446)
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    # of Collaborated Products: 0 results
  • 7.  MIYAKE Kensuke (60229812)
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  • 8.  中嶋 弘一 (00227787)
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  • 9.  金澤 伸雄 (90343227)
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    # of Collaborated Products: 0 results
  • 11.  KURATA Shoichiro (90221944)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KURANAGA Erina (90376591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  OGAWA Yoshihiro (70291424)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MARU Yoshiro (00251447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MATSUSHITA Sho (50167649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  UEMURA Yasushi (40364781)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  佐々木 泉 (80611037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 18.  山崎 晶 (40312946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  和泉 自泰 (70622166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  瀬川 勝盛 (20542971)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  安友 康二 (30333511)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  木村 元子 (00345018)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  浅野 謙一 (10513400)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  堀 昌平 (50392113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  ISE Masako
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  FUJII Shinーichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  FUKUDA Yuri
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 28.  FUKUSHIMA Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  邊見 弘明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 8 results
  • 30.  財賀 大行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  濱崎 洋子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  清水 佳奈子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  村嶋 亜紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  山田 源
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  志馬 寛明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  岩永 ひろみ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  大熊 敦史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 38.  鵜殿 平一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  久枝 一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  長谷 耕二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  尹 浩信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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