Yoshihara Toshihiro 吉原俊博

… Alternative Names

Researcher Number	60261319
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Affiliation (Current)	2020: 北海道大学, 歯学研究院, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2019: 北海道大学, 歯学研究院, 准教授 2016: 北海道大学, 歯学研究科, 准教授 2012 – 2015: 北海道大学, 歯学研究科(研究院), 准教授 2012: 北海道大学, 大学院・歯学研究科, 准教授 2011: 北海道大学, 大学病院, 講師 … More
Review Section/Research Field	Principal Investigator 矯正・小児・社会系歯学 / Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry / Basic Section 57070:Developmental dentistry-related Except Principal Investigator 矯正・小児・社会系歯学 / Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry
Keywords	Principal Investigator ラット / 身体抑制 / ストレス / 視床下部 / 中枢神経 / 中枢神経系 / HPA axis / ストレス反応性 / 成長 / 咬合の不調和 … More Except Principal Investigator 単純ヘルペスウイルス / 唾液 / PCR / polymerase chain reaction / in situ hybridization / STAI / 永久歯 / 先天性欠如 / 疫学調査 / 全国調査 / 発生頻度 / 歯種別 / 小児歯科学 / 発現頻度 / 頻度 / 歯列咬合異常 / 歯学 / 口唇閉鎖力 / アンケート / 顔面形態計測 / 口呼吸 / PCR法 / 急性疱疹性歯肉口内炎 / 電気泳動 / 単純ヘルペスウィルス / P.C.R法 / 口腔内ウィルス / 院内感染防止対策 / Herpes Simplex / Saliva / Herpetic Gingivostomatitis / マイコプラズマ / ポリメラーゼチェイン反応 / 一酸化窒素 / 一酸化窒素合成酵素 / in situハイブリダイゼーション / in situ PCR / 単純ヘルペスウイルス(HSV) / 一酸化窒素(NO) / NO合成酵素(NOS) / 培養線維芽細胞 / 口腔粘膜病変 / in situ ハイブリダイゼーション / HSV-1 / 一酸化窒素合成酵素(NOS) / herpes simplex virus / Mycoplasma salivarium / saliva / nitric oxide / nitric oxide synthase / 若年者 / 顎関節症 / 疫学 / 顎関節症症状 / 思春期 / 三次元有限要素モデル / 顎関節部負荷 / 顎関節症患者 / JRA / MRI / 画像診断 / Adolescent / Temporomandibular joint dysfunction (TMD) / epidemiology / sign of TMD / Puberty / Three-dimensional finite element model / TMJ loading Less

幼少期に身体抑制を経験したラットの成長後のストレス反応性亢進を緩和できるか。Principal InvestigatorOngoing
- Principal Investigator
  
  吉原俊博
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Hokkaido University
The relationship between the stress response and central nervous system in the the adult rat experienced immobilization stress in the early postnatal periodPrincipal Investigator
- Principal Investigator
  
  YOSHIHARA TOSHIHIRO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Hokkaido University
Effects of repeated immobilization stress in the early postnatal period on central nervous system, especially the hypothalamus in adult ratsPrincipal Investigator
- Principal Investigator
  
  Yoshihara Toshihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Hokkaido University
Relationship between mouth breathing and lip-closing strength and relevant factors for mouth breathing in children
- Principal Investigator
  
  Ishitani Norihito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Kagoshima University
The central nervous system in mice that spontaneously develop anterior transverse crossbitePrincipal Investigator
- Principal Investigator
  
  YOSHIHARA Toshihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Hokkaido University
An epidemiological survey about the prevalence of congenitally missing permanent teeth of Japanese children
- Principal Investigator
  
  YAMASAKI Youichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kagoshima University
The effect of repeated immobilization stress in the early postnatal period on the central nervous system in the adulthoodPrincipal Investigator
- Principal Investigator
  
  YOSHIHARA Toshihiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Hokkaido University
  Kagoshima University
The relationship between occiusal disharmony and hypothalamus in the ratPrincipal Investigator
- Principal Investigator
  
  YOSHIHARA Toshihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kagoshima University
The relationship between activation ofneurotransmitters by the mastication, learning, and memory : investigation of the mechanism by chronobiological methodPrincipal Investigator
- Principal Investigator
  
  YOSHIHARA Toshihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kagoshima University
A investigation or temporomandibular joint dysfunction syndrome in adolescents
- Principal Investigator
  
  OGURA Tadashi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kagoshima University
A neuroendocrinological study on the mechanism of activation of neurotransmitter by masticationPrincipal Investigator
- Principal Investigator
  
  YOSHIHARA Toshihiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kagoshima University
  Hokkaido University
小児歯科患者の単純ヘルペスウィルスと口腔粘膜疾患との関連に関する遺伝子学的研究Principal Investigator
- Principal Investigator
  
  吉原俊博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Hokkaido University
Application of in situ PCR to the diagnosis of oral diseases
- Principal Investigator
  
  OGUCHI Haruhisa
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  HOKKAIDO UNIVERSITY
The relation of Rerpes simplex and oral disease in Pediatric dentist, Patients.
- Principal Investigator
  
  KAGA Masayuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Hokkaido University

All 2019 2018 2015 2013 2012 2011 2010 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 時間生物学事典2008
- Author(s)
  吉原俊博
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-18592246
[Book] 第3版小児歯科学(編者赤坂守人, 佐々龍二, 高木裕三, 田村康夫, 西野瑞穂), 第2編成長発達, 4章頭蓋, 顎顔面の発育, I頭蓋の発育, II顎の発育, III発育の評価2007
- Author(s)
  吉原俊博, 山崎要一
- Total Pages
  442
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-19390532
[Journal Article] Daily life habits associated with eveningness lead to a higher prevalence of dental caries in children2019
- Author(s)
  Shinya Nishide, Toshihiro Yoshihara, Hirohisa Hongo, Takashi Kanehira, Yasutaka Yawaka
- Journal Title
  
  Journal of Dental Sciences
  
  Volume: 印刷中 Pages: 302-308
- DOI
  10.1016/j.jds.2019.01.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11799, KAKENHI-PROJECT-19K10394
[Journal Article] Oral findings in a patient with megacystis microcolon intestinal hypoperistalsis2018
- Author(s)
  Chihiro Takasaki, Toshihiro Yoshihara, Yasutaka Yawaka
- Journal Title
  
  Pediatric Dental Journal
  
  Volume: 28(2) Pages: 57-61
- DOI
  10.1016/j.pdj.2018.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11799
[Journal Article] The ventral ascending noradrenergic bundles are involved in the stress response to immobilization2015
- Author(s)
  Toshihiro Yoshihara, Yasutaka Yawaka
- Journal Title
  
  Journal of Behavioral and Brain Science
  
  Volume: Vol.5 No.3 Pages: 88-95
- DOI
  10.4236/jbbs.2015.53008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25463160
[Journal Article] Restricted daily feeding of liquid meal reduces the motivation of rats to get food2015
- Author(s)
  Toshihiro Yoshihara, Yasutaka Yawaka
- Journal Title
  
  Journal of Behavioral and Brain Science
  
  Volume: Vol.5 No.4 Pages: 130-136
- DOI
  10.4236/jbbs.2015.54013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25463160
[Journal Article] Differential effects of repeated immobilization stress in early versus late postnatal period on stress-induced corticosterone response in adult rats2013
- Author(s)
  Toshihiro Yoshihara, Yasutaka Yawaka
- Journal Title
  
  Neuroscience Letters
  
  Volume: 534 Pages: 30-34
- DOI
  10.1016/j.neulet.2012.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592275
[Journal Article] Lesions of the ventral ascending noradrenergic bundles decrease the stress response to occlusal disharmony in rats2011
- Author(s)
  Toshihiro Yoshihara, Yasutaka Yawaka
- Journal Title
  
  Neuroscience Letters
  
  Volume: 503(1) Pages: 43-47
- DOI
  10.1016/j.neulet.2011.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592275
[Journal Article] Condylar Shape in Relation to Anterior Disk Displacement in Juvenile Females2011
- Author(s)
  Hiroko Hasegawa,Issei,Saitoh, Kuniko Nakamura-Ohshima,Koki Shigeta, Toshihiro Yoshihara, Shigeaki Suenaga, Emi Inada, Tomonori Iwasaki,Yuko Matsumoto Hauaki Hayasaki, Youichi Yamasaki
- Journal Title
  
  The Journal of Craniomandibular Practice
  
  Volume: (印刷中,印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592275
[Journal Article] Youichi YamasakiCondylar Shape in Relation to Anterior Disk Displacement in Juvenile Females2011
- Author(s)
  Hiroko Hasegawa, Issei Saitoh, KunikoNakakura-Ohshima, Koki Shigeta,Toshihiro Yoshihara, Shigeaki Suenaga, Emi Inada, Tomonori Iwasaki, Yuko Matsumoto, Haruaki Hayasaki
- Journal Title
  
  The Journal of Craniomandibular Practice
  
  Volume: 29(2) Pages: 100-110
- URL
  http://www.ncbi.nlm.nih.gov/pubmed?cmd=Search&term=Condylar%20Shape%20in%20Relation%20to%20Anterior%20Disk%20Displacement%20in%20Juvenile%20Females&dispmax=20&relpubdate=No%20Limit
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592275
[Journal Article] Yasutaka YawakaAnomaly of cervical vertebrae that was first found on orthodontic examination: an 8-year-old boy with cleft lip and palate diagnosed with Klippel-Feil syndrome2010
- Author(s)
  Toshihiro Yoshihara, Junichi Suzuki
- Journal Title
  
  Angle Orthodontist
  
  Volume: 80(5) Pages: 975-80
- DOI
  10.2319/110409-620.1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592275
[Journal Article] Anomaly of cervical vertebrae that was first found on orthodontic examination : an 8-year-old boy with cleft lip and palate diagnosed with Klippel-Feil syndrome2010
- Author(s)
  Toshihiro Yoshihara, Junichi Suzuki, Yasutaka Yawaka
- Journal Title
  
  Angle orthodontist
  
  Volume: Sep ; 80(5) Pages: 975-980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592275
[Journal Article] 精神身体的状態が顎顔面部における圧痛閾値測定結果に及ぼす影響について2008
- Author(s)
  石谷徳人, 吉原俊博, 舛元康浩, 齋藤一誠, 稲田絵美, 山崎要一
- Journal Title
  
  小児歯科学雑誌 46(1)
  
  Pages: 19-25
- NAID
  10024179458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592246
[Journal Article] Repeated immobilization stress in the early postnatal period in creases stress response in adult rats.2008
- Author(s)
  Toshihiro Yoshihara
- Journal Title
  
  Physiology and Behavior 93
  
  Pages: 322-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592246
[Journal Article] Repeated immobilization stress in the early postnatal period increases stress response in adult rats2008
- Author(s)
  Toshihiro Yoshihara, Yasutaka Yawaka
- Journal Title
  
  Physiology and Behavior 93(1-2)
  
  Pages: 322-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592246
[Journal Article] 生後の環境が中枢神経系に与える影響についての統合的理解2008
- Author(s)
  吉原俊博
- Journal Title
  
  小児歯科学雑誌 46(5)
  
  Pages: 497-500
- NAID
  10027487044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592246
[Journal Article] Maternal deprivation in the early versus late postnatal period differentially affects growth and stress-induced corticosterone responses in adolescent rats2006
- Author(s)
  Yuko Matsumoto, Toshihiro Yoshihara, Youichi Yamasaki
- Journal Title
  
  Brain Research 1115(1)
  
  Pages: 155-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592246
[Journal Article] Repeated immobilization stress in the early postnatal period increases stress resnonse in adult rats
- Author(s)
  Toshihiro Yoshihara
- Journal Title
  
  Physiology and Behavior 93(1-2)
  
  Pages: 322-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592246
[Presentation] ラット身体抑制による血中コルチコステロン上昇には脳幹からの上行性カテコールアミンニューロンが関与する2012
- Author(s)
  吉原俊博
- Organizer
  第２９回日本障害者歯科学会総会および学術大会
- Place of Presentation
  札幌コンベンションセンター（札幌市）
- Data Source
  KAKENHI-PROJECT-22592275
[Presentation] ラット身体抑制による血中コルチコステロン上昇には脳幹からの上行性カテコールアミンニューロンが関与する2012
- Author(s)
  吉原俊博,八若保孝
- Organizer
  第29回日本障害者歯科学会総会および学術大会
- Place of Presentation
  札幌コンベンションセンター,札幌
- Data Source
  KAKENHI-PROJECT-22592275
[Presentation] 生後の環境が中枢神経系に与える影響についての統合的理解2008
- Author(s)
  吉原俊博
- Organizer
  第46回日本小児歯科学会大会
- Place of Presentation
  大宮ソニックシティ(さいたま市)
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-18592246
[Presentation] 生後の環境が中枢神経系に与える影響についての統合的理解2008
- Author(s)
  吉原俊博
- Organizer
  第46回日本小児歯科学会大会
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-18592246

1. OSHIMA Shohei (00374546)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. TAKASAKI Chihiro (60451449)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. SAITHO Issei (90404540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ISHITANI Norihito (90343368)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. HASEGAWA Hiroko (00295271)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. INADA Emi (30448568)

# of Collaborated Projects: 2 results

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7. KIKUIRI TAKASHI (10322819)

# of Collaborated Projects: 2 results

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8. SHIRAKAWA Tetsuo (00187527)

# of Collaborated Projects: 2 results

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9. MATSUMOTO Yuko (20315443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. YAMASAKI Youichi (30200645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. IWASAKI Tomonori (10264433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAYASAKI Haruaki (60238095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOKUTOMI Junko (80433077)

# of Collaborated Projects: 1 results

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14. YAWAKA Yasutaka (60230603)

# of Collaborated Projects: 1 results

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15. INOUE Mitsuko (20112724)

# of Collaborated Projects: 1 results

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16. ASADA Yoshinobu (20184145)

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17. TAMURA Yasuo (40113047)

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18. KANOMI Ryuzo (70411444)

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19. MAKI Kenshi (60209400)

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20. FUNATSU Takahiro (50337169)

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21. TESHIMA Yoko (50433826)

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22. UESATO Chika (30449087)

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23. YAMASHITA Kazue (60514990)

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24. IDE Masamichi (50193462)

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25. KURIYAMA Tihiro (00410051)

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26. MUKAI Ayako (50460233)

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27. KONDO Tsuguko (10350878)

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28. KATOH Mikio (60131380)

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29. WATANABE Kyoko (80434794)

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30. FUJITA Yuuko (90514670)

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31. KAIHARA Yasutaka (60274106)

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32. KAGA Masayuki (70125300)

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33. OGUCHI Haruhisa (30124689)

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34. KUDO Masaki (10164500)

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35. OGURA Tadashi (00059362)

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36. SHIGETA Koki (10274854)

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37. MORINUSHI Takanobu (60128460)

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38. IMANAKA Hiroyuki (80223329)

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39. NISHIDE Shinya

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# of Collaborated Products: 1 results

Yoshihara Toshihiro 吉原 俊博

YOSHIHARA Toshihiro 吉原 俊博

Research Projects

Research Products

Co-Researchers

幼少期に身体抑制を経験したラットの成長後のストレス反応性亢進を緩和できるか。Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The relationship between the stress response and central nervous system in the the adult rat experienced immobilization stress in the early postnatal periodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of repeated immobilization stress in the early postnatal period on central nervous system, especially the hypothalamus in adult ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relationship between mouth breathing and lip-closing strength and relevant factors for mouth breathing in children

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The central nervous system in mice that spontaneously develop anterior transverse crossbitePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An epidemiological survey about the prevalence of congenitally missing permanent teeth of Japanese children

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of repeated immobilization stress in the early postnatal period on the central nervous system in the adulthoodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The relationship between occiusal disharmony and hypothalamus in the ratPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The relationship between activation ofneurotransmitters by the mastication, learning, and memory : investigation of the mechanism by chronobiological methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A investigation or temporomandibular joint dysfunction syndrome in adolescents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A neuroendocrinological study on the mechanism of activation of neurotransmitter by masticationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

小児歯科患者の単純ヘルペスウィルスと口腔粘膜疾患との関連に関する遺伝子学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of in situ PCR to the diagnosis of oral diseases

Principal Investigator

Project Period (FY)

Yoshihara Toshihiro 吉原俊博

YOSHIHARA Toshihiro 吉原俊博

[Book] 第3版小児歯科学(編者赤坂守人, 佐々龍二, 高木裕三, 田村康夫, 西野瑞穂), 第2編成長発達, 4章頭蓋, 顎顔面の発育, I頭蓋の発育, II顎の発育, III発育の評価2007