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Yoshihara Toshihiro  吉原 俊博

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… Alternative Names

YOSHIHARA Toshihiro  吉原 俊博

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Researcher Number 60261319
Other IDs
External Links
Affiliation (Current) 2021: 北海道大学, 歯学研究院, 准教授
Affiliation (based on the past Project Information) *help 2017 – 2019: 北海道大学, 歯学研究院, 准教授
2016: 北海道大学, 歯学研究科, 准教授
2012 – 2015: 北海道大学, 歯学研究科(研究院), 准教授
2012: 北海道大学, 大学院・歯学研究科, 准教授
2011: 北海道大学, 大学病院, 講師 … More
2010: 北海道大学, 病院, 講師
2008: Hokkaido University, 病院, 講師
2008: 北海道大学病院, 歯科診療センター, 講師
2007 – 2008: Hokkaido University, 北海道大学病院, 講師
2006: 鹿児島大学, 医学部・歯学部附属病院, 講師
2003: Kagoshirna University, University Hospital, Faculty of Medicine and Dentistry, Assistant Professor, 医学部・歯学部附属病院, 講師
2001 – 2002: 鹿児島大学, 歯学部附属病院, 講師
1999 – 2001: Kagoshima University, Dental Hospital, Assistant Professor, 歯学部・附属病院, 講師
1997 – 1998: 北海道大学, 歯学部, 助手
1995 – 1996: 北海道大学, 歯学部・附属病院, 助手
1995: Hokkaido Univ., Dent. Hospital, Inct., 歯学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
矯正・小児・社会系歯学 / Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry / Basic Section 57070:Developmental dentistry-related
Except Principal Investigator
矯正・小児・社会系歯学 / Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry
Keywords
Principal Investigator
ラット / 身体抑制 / ストレス / 視床下部 / 中枢神経 / 中枢神経系 / HPA axis / ストレス反応性 / 成長 / 咬合の不調和 … More / 学習 / 記憶 / learning / memory / コルチコステロン / corticosterone / PCR法 / 唾液 / 単純ヘルペス / 身体抑制ストレス / 不正咬合 / マウス / フウス / ストレス反応 / HPAaxis / 咀嚼 / ニューロペプタイドY / 迷路学習 / mastication / neuropeptide Y / rat / 周期的制限給餌 / restricted daily feeding / 行動量 / 睡眠 / occlusal disharmony / locomotor activity / restrsleeping / hypothalamus / stress / 視床下部下垂体副腎皮質系 / 大脳辺縁系 … More
Except Principal Investigator
単純ヘルペスウイルス / 唾液 / PCR / polymerase chain reaction / in situ hybridization / STAI / 永久歯 / 先天性欠如 / 疫学調査 / 全国調査 / 発生頻度 / 歯種別 / 小児歯科学 / 発現頻度 / 頻度 / 歯列咬合異常 / 歯学 / 口唇閉鎖力 / アンケート / 顔面形態計測 / 口呼吸 / PCR法 / 急性疱疹性歯肉口内炎 / 電気泳動 / 単純ヘルペスウィルス / P.C.R法 / 口腔内ウィルス / 院内感染防止対策 / Herpes Simplex / Saliva / Herpetic Gingivostomatitis / マイコプラズマ / ポリメラーゼチェイン反応 / 一酸化窒素 / 一酸化窒素合成酵素 / in situハイブリダイゼーション / in situ PCR / 単純ヘルペスウイルス(HSV) / 一酸化窒素(NO) / NO合成酵素(NOS) / 培養線維芽細胞 / 口腔粘膜病変 / in situ ハイブリダイゼーション / HSV-1 / 一酸化窒素合成酵素(NOS) / herpes simplex virus / Mycoplasma salivarium / saliva / nitric oxide / nitric oxide synthase / 若年者 / 顎関節症 / 疫学 / 顎関節症症状 / 思春期 / 三次元有限要素モデル / 顎関節部負荷 / 顎関節症患者 / JRA / MRI / 画像診断 / Adolescent / Temporomandibular joint dysfunction (TMD) / epidemiology / sign of TMD / Puberty / Three-dimensional finite element model / TMJ loading Less
  • Research Projects

    (14 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (39 People)
  •  幼少期に身体抑制を経験したラットの成長後のストレス反応性亢進を緩和できるか。Principal InvestigatorOngoing

    • Principal Investigator
      吉原 俊博
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Hokkaido University
  •  The relationship between the stress response and central nervous system in the the adult rat experienced immobilization stress in the early postnatal periodPrincipal Investigator

    • Principal Investigator
      YOSHIHARA TOSHIHIRO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Hokkaido University
  •  Effects of repeated immobilization stress in the early postnatal period on central nervous system, especially the hypothalamus in adult ratsPrincipal Investigator

    • Principal Investigator
      Yoshihara Toshihiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Hokkaido University
  •  Relationship between mouth breathing and lip-closing strength and relevant factors for mouth breathing in children

    • Principal Investigator
      Ishitani Norihito
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Kagoshima University
  •  The central nervous system in mice that spontaneously develop anterior transverse crossbitePrincipal Investigator

    • Principal Investigator
      YOSHIHARA Toshihiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Hokkaido University
  •  An epidemiological survey about the prevalence of congenitally missing permanent teeth of Japanese children

    • Principal Investigator
      YAMASAKI Youichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Kagoshima University
  •  The effect of repeated immobilization stress in the early postnatal period on the central nervous system in the adulthoodPrincipal Investigator

    • Principal Investigator
      YOSHIHARA Toshihiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Hokkaido University
      Kagoshima University
  •  The relationship between occiusal disharmony and hypothalamus in the ratPrincipal Investigator

    • Principal Investigator
      YOSHIHARA Toshihiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Kagoshima University
  •  The relationship between activation ofneurotransmitters by the mastication, learning, and memory : investigation of the mechanism by chronobiological methodPrincipal Investigator

    • Principal Investigator
      YOSHIHARA Toshihiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Kagoshima University
  •  A investigation or temporomandibular joint dysfunction syndrome in adolescents

    • Principal Investigator
      OGURA Tadashi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Kagoshima University
  •  A neuroendocrinological study on the mechanism of activation of neurotransmitter by masticationPrincipal Investigator

    • Principal Investigator
      YOSHIHARA Toshihiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Kagoshima University
      Hokkaido University
  •  小児歯科患者の単純ヘルペスウィルスと口腔粘膜疾患との関連に関する遺伝子学的研究Principal Investigator

    • Principal Investigator
      吉原 俊博
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Hokkaido University
  •  Application of in situ PCR to the diagnosis of oral diseases

    • Principal Investigator
      OGUCHI Haruhisa
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  The relation of Rerpes simplex and oral disease in Pediatric dentist, Patients.

    • Principal Investigator
      KAGA Masayuki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Hokkaido University

All 2019 2018 2015 2013 2012 2011 2010 2008 2007 2006 Other

All Journal Article Presentation Book

  • [Book] 時間生物学事典2008

    • Author(s)
      吉原俊博
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-18592246
  • [Book] 第3版 小児歯科学(編者 赤坂守人, 佐々龍二, 高木裕三, 田村康夫, 西野瑞穂), 第2編 成長発達, 4章 頭蓋, 顎顔面の発育, I頭蓋の発育, II顎の発育, III発育の評価2007

    • Author(s)
      吉原俊博, 山崎要一
    • Total Pages
      442
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-19390532
  • [Journal Article] Daily life habits associated with eveningness lead to a higher prevalence of dental caries in children2019

    • Author(s)
      Shinya Nishide, Toshihiro Yoshihara, Hirohisa Hongo, Takashi Kanehira, Yasutaka Yawaka
    • Journal Title

      Journal of Dental Sciences

      Volume: 印刷中 Pages: 302-308

    • DOI

      10.1016/j.jds.2019.01.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11799, KAKENHI-PROJECT-19K10394
  • [Journal Article] Oral findings in a patient with megacystis microcolon intestinal hypoperistalsis2018

    • Author(s)
      Chihiro Takasaki, Toshihiro Yoshihara, Yasutaka Yawaka
    • Journal Title

      Pediatric Dental Journal

      Volume: 28(2) Pages: 57-61

    • DOI

      10.1016/j.pdj.2018.05.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11799
  • [Journal Article] Restricted daily feeding of liquid meal reduces the motivation of rats to get food2015

    • Author(s)
      Toshihiro Yoshihara, Yasutaka Yawaka
    • Journal Title

      Journal of Behavioral and Brain Science

      Volume: Vol.5 No.4 Pages: 130-136

    • DOI

      10.4236/jbbs.2015.54013

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25463160
  • [Journal Article] The ventral ascending noradrenergic bundles are involved in the stress response to immobilization2015

    • Author(s)
      Toshihiro Yoshihara, Yasutaka Yawaka
    • Journal Title

      Journal of Behavioral and Brain Science

      Volume: Vol.5 No.3 Pages: 88-95

    • DOI

      10.4236/jbbs.2015.53008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25463160
  • [Journal Article] Differential effects of repeated immobilization stress in early versus late postnatal period on stress-induced corticosterone response in adult rats2013

    • Author(s)
      Toshihiro Yoshihara, Yasutaka Yawaka
    • Journal Title

      Neuroscience Letters

      Volume: 534 Pages: 30-34

    • DOI

      10.1016/j.neulet.2012.12.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592275
  • [Journal Article] Condylar Shape in Relation to Anterior Disk Displacement in Juvenile Females2011

    • Author(s)
      Hiroko Hasegawa,Issei,Saitoh, Kuniko Nakamura-Ohshima,Koki Shigeta, Toshihiro Yoshihara, Shigeaki Suenaga, Emi Inada, Tomonori Iwasaki,Yuko Matsumoto Hauaki Hayasaki, Youichi Yamasaki
    • Journal Title

      The Journal of Craniomandibular Practice

      Volume: (印刷中,印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592275
  • [Journal Article] Lesions of the ventral ascending noradrenergic bundles decrease the stress response to occlusal disharmony in rats2011

    • Author(s)
      Toshihiro Yoshihara, Yasutaka Yawaka
    • Journal Title

      Neuroscience Letters

      Volume: 503(1) Pages: 43-47

    • DOI

      10.1016/j.neulet.2011.08.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592275
  • [Journal Article] Youichi YamasakiCondylar Shape in Relation to Anterior Disk Displacement in Juvenile Females2011

    • Author(s)
      Hiroko Hasegawa, Issei Saitoh, KunikoNakakura-Ohshima, Koki Shigeta,Toshihiro Yoshihara, Shigeaki Suenaga, Emi Inada, Tomonori Iwasaki, Yuko Matsumoto, Haruaki Hayasaki
    • Journal Title

      The Journal of Craniomandibular Practice

      Volume: 29(2) Pages: 100-110

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed?cmd=Search&term=Condylar%20Shape%20in%20Relation%20to%20Anterior%20Disk%20Displacement%20in%20Juvenile%20Females&dispmax=20&relpubdate=No%20Limit

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592275
  • [Journal Article] Anomaly of cervical vertebrae that was first found on orthodontic examination : an 8-year-old boy with cleft lip and palate diagnosed with Klippel-Feil syndrome2010

    • Author(s)
      Toshihiro Yoshihara, Junichi Suzuki, Yasutaka Yawaka
    • Journal Title

      Angle orthodontist

      Volume: Sep ; 80(5) Pages: 975-980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592275
  • [Journal Article] Yasutaka YawakaAnomaly of cervical vertebrae that was first found on orthodontic examination: an 8-year-old boy with cleft lip and palate diagnosed with Klippel-Feil syndrome2010

    • Author(s)
      Toshihiro Yoshihara, Junichi Suzuki
    • Journal Title

      Angle Orthodontist

      Volume: 80(5) Pages: 975-80

    • DOI

      10.2319/110409-620.1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592275
  • [Journal Article] Repeated immobilization stress in the early postnatal period increases stress response in adult rats2008

    • Author(s)
      Toshihiro Yoshihara, Yasutaka Yawaka
    • Journal Title

      Physiology and Behavior 93(1-2)

      Pages: 322-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592246
  • [Journal Article] 生後の環境が中枢神経系に与える影響についての統合的理解2008

    • Author(s)
      吉原俊博
    • Journal Title

      小児歯科学雑誌 46(5)

      Pages: 497-500

    • NAID

      10027487044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592246
  • [Journal Article] 精神身体的状態が顎顔面部における圧痛閾値測定結果に及ぼす影響について2008

    • Author(s)
      石谷徳人, 吉原俊博, 舛元康浩, 齋藤一誠, 稲田絵美, 山崎要一
    • Journal Title

      小児歯科学雑誌 46(1)

      Pages: 19-25

    • NAID

      10024179458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592246
  • [Journal Article] Repeated immobilization stress in the early postnatal period in creases stress response in adult rats.2008

    • Author(s)
      Toshihiro Yoshihara
    • Journal Title

      Physiology and Behavior 93

      Pages: 322-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592246
  • [Journal Article] Maternal deprivation in the early versus late postnatal period differentially affects growth and stress-induced corticosterone responses in adolescent rats2006

    • Author(s)
      Yuko Matsumoto, Toshihiro Yoshihara, Youichi Yamasaki
    • Journal Title

      Brain Research 1115(1)

      Pages: 155-161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592246
  • [Journal Article] Repeated immobilization stress in the early postnatal period increases stress resnonse in adult rats

    • Author(s)
      Toshihiro Yoshihara
    • Journal Title

      Physiology and Behavior 93(1-2)

      Pages: 322-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592246
  • [Presentation] ラット身体抑制による血中コルチコステロン上昇には脳幹からの上行性カテコールアミンニューロンが関与する2012

    • Author(s)
      吉原俊博,八若保孝
    • Organizer
      第29回日本障害者歯科学会総会および学術大会
    • Place of Presentation
      札幌コンベンションセンター,札幌
    • Data Source
      KAKENHI-PROJECT-22592275
  • [Presentation] ラット身体抑制による血中コルチコステロン上昇には脳幹からの上行性カテコールアミンニューロンが関与する2012

    • Author(s)
      吉原俊博
    • Organizer
      第29回日本障害者歯科学会総会および学術大会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Data Source
      KAKENHI-PROJECT-22592275
  • [Presentation] 生後の環境が中枢神経系に与える影響についての統合的理解2008

    • Author(s)
      吉原俊博
    • Organizer
      第46回日本小児歯科学会大会
    • Place of Presentation
      埼玉
    • Data Source
      KAKENHI-PROJECT-18592246
  • [Presentation] 生後の環境が中枢神経系に与える影響についての統合的理解2008

    • Author(s)
      吉原俊博
    • Organizer
      第46回日本小児歯科学会大会
    • Place of Presentation
      大宮ソニックシティ(さいたま市)
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-18592246
  • 1.  OSHIMA Shohei (00374546)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  TAKASAKI Chihiro (60451449)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  SAITHO Issei (90404540)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  ISHITANI Norihito (90343368)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  HASEGAWA Hiroko (00295271)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  INADA Emi (30448568)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KIKUIRI TAKASHI (10322819)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SHIRAKAWA Tetsuo (00187527)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  MATSUMOTO Yuko (20315443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  YAMASAKI Youichi (30200645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  IWASAKI Tomonori (10264433)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HAYASAKI Haruaki (60238095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TOKUTOMI Junko (80433077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YAWAKA Yasutaka (60230603)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  INOUE Mitsuko (20112724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ASADA Yoshinobu (20184145)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TAMURA Yasuo (40113047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KANOMI Ryuzo (70411444)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MAKI Kenshi (60209400)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  FUNATSU Takahiro (50337169)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TESHIMA Yoko (50433826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  UESATO Chika (30449087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  YAMASHITA Kazue (60514990)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  IDE Masamichi (50193462)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KURIYAMA Tihiro (00410051)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MUKAI Ayako (50460233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  KONDO Tsuguko (10350878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KATOH Mikio (60131380)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  WATANABE Kyoko (80434794)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  FUJITA Yuuko (90514670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  KAIHARA Yasutaka (60274106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  KAGA Masayuki (70125300)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  OGUCHI Haruhisa (30124689)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  KUDO Masaki (10164500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  OGURA Tadashi (00059362)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  SHIGETA Koki (10274854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  MORINUSHI Takanobu (60128460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  IMANAKA Hiroyuki (80223329)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  NISHIDE Shinya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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