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Shimabukuro Michio  島袋 充生

… Alternative Names

島袋 充生  シマブクロ ミチオ

SHIMABUKURO Michio  島袋 充生

Less
Researcher Number 60271144
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7835-7665
External Links
Affiliation (Current) 2025: 福島県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2025: 福島県立医科大学, 医学部, 教授
2022 – 2023: 福島県立医科大学, 医学部, 教授
2016 – 2020: 福島県立医科大学, 医学部, 教授
2014: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 特任教授
2014: 徳島大学, 大学院医歯薬学研究部 心臓血管病態医学分野, 特任教授 … More
2012 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 教授
2011 – 2013: 徳島大学, ヘルスバイオサイエンス研究部, 特任教授
2012: 琉球大学, 医学部附属病院, 講師
2010: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 特任教授
2002 – 2010: University of the Ryukyus, Department of Medicine, Assistant Professor, 医学部附属病院, 講師
2007: University of the Ryukyus, Department of Internal Medicine, Associate Professor
2001: 琉球大学, 医学部・付属病院, 講師
2000 – 2001: UNIV OF THE RYUKYUS, MEDICINE, ASSISTANT PROFESSOR, 医学部, 講師
1999 – 2001: 琉球大学, 医学部・附属病院, 講師
1998: 琉球大学, 医学部, 助手
1995: 琉球大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Metabolomics / Applied health science / Metabolomics / Public health/Health science / Circulatory organs internal medicine
Except Principal Investigator
Endocrinology / Basic Section 08030:Family and consumer sciences, and culture and living-related / Eating habits / Pediatrics … More / Circulatory organs internal medicine / Metabolomics / Metabolomics / Circulatory organs internal medicine / Endocrinology / Applied pharmacology / Biological Sciences Less
Keywords
Principal Investigator
糖尿病 / インスリン抵抗性 / 異所性脂肪 / 内臓肥満症 / 遺伝子多型 / 身体活動 / 食行動 / 2型糖尿病 / 生活習慣病 / サルコペニア … More / 心臓血管病 / leptin / insulin / diabetes mellitus / レプチン / インスリン / 遊離脂肪酸 / 内蔵肥満症 / メタボリックシンドローム / 活性酸素種 / 心筋梗塞 / 血管内皮機能 / lipotoxicity(脂肪毒性) / 膵β細胞 / 肥満 / 冠動脈血管内皮細胞機能 / 冠動脈攣縮性狭心症 / Syndrome X / 高インスリン血症 … More
Except Principal Investigator
糖尿病 / 動脈硬化 / CTLA-4 / octn2 / 食行動 / 脂質異常症 / 分子シャペロン / 視床下部 / 肥満 / インスリン抵抗性 / 血管内皮機能 / 腸内フローラ / 食行動異常 / 脳腸相関 / adipocytokine / metabolic syndrome / atherosclerosis / Dyslipidemia / life-style related disease in children / CRP / アディポネクチン / 小児肥満 / 生下時体重 / IMT / FMD / アディポサイトカイン / メタボリック症候群 / 小児生活習慣病 / TRAb (TSH receptor Ab) / TSAb (thyroid stimulating Ab) / Remission / Hyperthyroidism / Graves' disease / CTLA-4遺伝子多形 / 高感度TSAb / 遺伝子異常 / 放射線療法 / CTLA-4遺伝子多型 / 抗甲状腺剤 / 緩解 / 甲状腺刺激抗体(TSAb) / TSH受容体抗体(TRAb) / バセドウ病 / RCT of diuretics / Nitric Oxide / AGE inhibitor / oxidative stress / bradykinin / Angiotensin II / angiotensin(1-7) / プレシスモグラフ / 前腕血流量 / アンジオテンシン変換酵素 / ACE阻害薬 / 心不全 / 降圧利尿薬臨床試験 / NOクランプ法 / 抗酸化作用 / 酸化ストレス / ブラジキニン / アンジオテンシンII / アンジオテンシン(1-7) / fatty acid / 2-DG uptake / glucagon / JVS mouse / insulin / carintine transporter / carnitine / 膵ラ氏島 / 脂肪毒性 / 高血糖 / 長鎖脂肪酸 / 膵β細胞 / 脂肪酸 / 2-DG取り込み / グルカゴン / octn 2 / JVSマウス / インスリン / カルニチン輸送担体 / カルニチン / RENIN-ANGIPTENSIN SYSTEM / POLYMORPHISM / CYTOCHROME P-450 / ALDOSTERONE / HYPERTENSION, ESSENTIAL / レニン活性 / アルドステロン / 遺伝子多型 / CYP11B2 / 本態性高血圧 / γオリザノール / 肥満症 / γ-オリザノール / 嗜好性 / 小胞体ストレス / 高脂肪食 / 血管内皮機能障害 / 玄米 / キサンチンオキシダーゼ / メタボリックシンドローム / 視床下部小胞体ストレス / レプチン抵抗性 / 代替エンドポイント / 薬効評価 / 臨床薬理学 / エピジェネティクス / 多因子疾患 / レトロトランスポゾン / ヒト内在性レトロウイルス Less
  • Research Projects

    (20 results)
  • Research Products

    (161 results)
  • Co-Researchers

    (46 People)
  •  GWASを用いた糖尿病サブクラス病態の解明:多遺伝子リスクスコアの開発Principal Investigator

    • Principal Investigator
      島袋 充生
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Fukushima Medical University
  •  Interpretation of pathophysiology of new diabetes subclass: genetic background of alteration of eating behavior and physical activityPrincipal Investigator

    • Principal Investigator
      島袋 充生
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Fukushima Medical University
  •  Mechanism of new diabetes onset in low fasting glucose level

    • Principal Investigator
      Ogata Emi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 08030:Family and consumer sciences, and culture and living-related
    • Research Institution
      Fukushima Medical University
  •  Dietary Behavior and Diabetes: An Analysis of Brain-Gut Axis Mechanisms

    • Principal Investigator
      KUDO AKIHIRO
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Eating habits
    • Research Institution
      Fukushima Medical University
  •  Elucidation of concept of ectopic fat consortium of cardiac fat, ectopic fat and sarcopenia and life-style diseasesPrincipal Investigator

    • Principal Investigator
      Shimabukuro Michio
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Fukushima Medical University
  •  mechanisms of vascular endothelial function in metabolic syndrome subjects and novel therapeutic approach

    • Principal Investigator
      YAMAKAWA Ken
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of the Ryukyus
  •  Exploration of novel hypothalamic mechanism on fatty food preference and its application to clinical science on obesity-diabetes syndrome

    • Principal Investigator
      MASUZAKI Hiroaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      University of the Ryukyus
  •  Role of ectopic fat in the mechanism of cardiovascular diseasesPrincipal Investigator

    • Principal Investigator
      SHIMABUKURO Michio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokushima
  •  Exposure to Artificial Sweetener in Juvenile Mice Intensifies Addictionto High-Fat Diet and Exaggerates Leptin Resistance in Adulthood

    • Principal Investigator
      YABIKU Kouichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      University of the Ryukyus
  •  Development of pharmacometric system for anti-atherogenic effect based on vascular endothelial function

    • Principal Investigator
      YAMAKAWA Ken
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      University of the Ryukyus
  •  Mechanism for vascular dysfunction caused by visceral fat-derived reactive oxygen speciesPrincipal Investigator

    • Principal Investigator
      SHIMABUKURO Michio
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Public health/Health science
    • Research Institution
      University of the Ryukyus
  •  Relationship between lifestyle-related diseases in childhood and the risk for atherosclerotic coronary heart disease in adulthood (studies on lipoprotein abnormality, adipocytokine, vascular endothelial function and related genes)

    • Principal Investigator
      OHTA Takao
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      University of the Ryukyus
  •  Molecular mechanism of lipotoxicity Functional analysis by adnovirus OBORb and PPARaPrincipal Investigator

    • Principal Investigator
      SHIMABUKURO Michio
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      University of the Ryukyus
  •  活性型内在性レトロウイルス遺伝子の包括的単離と多因子疾患への関わり

    • Principal Investigator
      小田 高也
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      University of the Ryukyus
  •  Role of Angiotensin (1-7) in therapeutic application of inhibition of rennin-angiotensin system in man

    • Principal Investigator
      UEDA Shinichiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of the Ryukyus
      Yokohama City University
  •  Remission of Graves' Hyperthyroidism and CTLA-4-Gene

    • Principal Investigator
      TAKASU Nobuyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      University of the Ryukyus
  •  Is lipotoxicity caused by the intracellular accumulation ofacyl CoA ?

    • Principal Investigator
      KUWAJIMA Masamichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokushima
  •  膵β細胞lipotoxicityの糖尿病発症における役割とその分子機構Principal Investigator

    • Principal Investigator
      島袋 充生
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Metabolomics
    • Research Institution
      University of the Ryukyus
  •  ANALYSIS OF GENES IN PATIENTS WITH ESSENTIAL HYPERTENSION : ADRENAL ENZYME ABNORMALITY AND HYPERTENSION

    • Principal Investigator
      KOMIYA Ichiro
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      UNIVERSITY OF THE RYUKYUS
  •  高インスリン血症と耐糖能障害の冠動脈血管内皮細胞機能におよぼす影響Principal Investigator

    • Principal Investigator
      島袋 充生
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of the Ryukyus

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] 慢性的 高脂肪食習慣 に伴う 視床下部の炎症と小胞体ストレス (特集:臓器間 代謝ネットワークと糖尿病):Diabetes Frontier2014

    • Author(s)
      益崎 裕章、小塚 智沙代、中山 良朗、島袋 充生
    • Publisher
      メデイカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Book] 沖縄クライシスの現状と新たなチャレンジ:最新医学 肥満症 - 病態・診断・治療2013

    • Author(s)
      益崎 裕章、島袋 充生
    • Publisher
      最新医学社
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Book] メタボリックシンドローム における 肝臓の役割:内分泌学 からの アプローチ 特集:肝疾患における臓器相関のup-to-date: 肝臓2012

    • Author(s)
      益崎 裕章、平良 伸一郎、小塚 智沙代、屋比久 浩市、島袋 充生
    • Publisher
      日本肝臓学会
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Book] メタボリックシンドロームと糖尿病:最近の知見: 糖尿病学の進歩 第46集2012

    • Author(s)
      益崎 裕章、小塚 智沙代、島袋 充生、 屋比久 浩市
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Book] 肥満と肥満症:糖尿病 発症 との 関わり 最新 臨床糖尿病学(上)2012

    • Author(s)
      益崎 裕章、屋比久 浩市、小塚 智沙代、平良 伸一郎、島袋 充生
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Book] 海外文献紹介・ビリルビンを増加させるHIV治療薬アタザナビルは2型糖尿病患者の血管内皮機能を改善する.Angiology Frontier. 102011

    • Author(s)
      島袋充生, 山川研, 益崎裕章
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-20590542
  • [Book] 肥満の脂肪組織における炎症.血管医学.122011

    • Author(s)
      小塚智沙代, 比嘉盛丈, 屋比久浩市, 島袋充生, 山川研, 益崎裕章
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-20590542
  • [Book] テルミサルタン内服により降圧とともに内臓脂肪面積減少と糖代謝改善が得られた症例.セラピューティックリサーチ.322011

    • Author(s)
      山川研, 島袋充生, 比嘉盛丈, 島袋毅, 田仲秀明, 益崎裕章
    • Publisher
      ライフサイエンス出版
    • Data Source
      KAKENHI-PROJECT-20590542
  • [Book] 脂肪組織グルココルチコイド作用過剰とアディポサイエンス.アディポサイエンス,72010

    • Author(s)
      益崎裕章, 山川研, 島袋充生
    • Publisher
      フジメディカル出版
    • Data Source
      KAKENHI-PROJECT-20590542
  • [Book] 異所性脂肪《メタボリックシンドロームの新常識》2010

    • Author(s)
      島袋充生、益崎裕章
    • Publisher
      日本医事新報
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Book] チーム医療レベルアップ糖尿病セミナー(第3巻)ケアネットDVD2009

    • Author(s)
      田中逸、赤井裕輝、島袋充生、穴澤園子
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Book] 糖尿病学の進歩 第42集2008

    • Author(s)
      島袋充生
    • Total Pages
      289
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Book] 糖尿病学2005

    • Author(s)
      島袋充生(共著)
    • Publisher
      西村書店(印刷中)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 動脈硬化性疾患治療の新たなストラテジー:メタボリックシンドロームとしてとらえる脂質代謝異常2005

    • Author(s)
      島袋充生(共著)
    • Publisher
      先端医学社(印刷中)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] アンチエイジング医学の基礎と臨床2004

    • Author(s)
      島袋充生
    • Total Pages
      340
    • Publisher
      メディカルビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 興和医報別冊 メタボリックシンドロー厶(共著)2004

    • Author(s)
      島袋充生(共著)
    • Total Pages
      103
    • Publisher
      医事出版社
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] シミュレイション内科学 糖尿病を探る2004

    • Author(s)
      島袋充生(共著)
    • Total Pages
      183
    • Publisher
      金原出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 興和医報別冊 メタボリックシンドローム(共著)2004

    • Author(s)
      島袋充生(共著)
    • Total Pages
      103
    • Publisher
      医事出版社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 糖尿病・代謝症候群 state of arts 2004-20062004

    • Author(s)
      島袋充生(共著)
    • Total Pages
      861
    • Publisher
      医歯薬出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 糖尿病・代謝症候群state of arts 2004-20062004

    • Author(s)
      島袋充生(共著)
    • Total Pages
      861
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] The Frontier in Medical Sciences:メタボリックシンドローム:メカニズムと治療の分子生物学2004

    • Author(s)
      島袋充生(共著)
    • Total Pages
      176
    • Publisher
      南山堂
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 糖尿病カレントライブラリー:インスリン分泌2004

    • Author(s)
      島袋充生(共著)
    • Total Pages
      195
    • Publisher
      文光堂
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 血管不全フロンティア2004

    • Author(s)
      島袋充生(共著)
    • Total Pages
      374
    • Publisher
      メディカルレビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 食後高血糖:循環器医が治療する糖尿病と大血管障害2004

    • Author(s)
      島袋充生
    • Total Pages
      323
    • Publisher
      メディカルビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Book] 食後高血糖/IGTと大血管障害2003

    • Author(s)
      島袋充生
    • Total Pages
      323
    • Publisher
      メディカルビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Fast walking is a preventive factor against new-onset diabetes mellitus in a large cohort from a Japanese general population2021

    • Author(s)
      Iwasaki M, Kudo A, Asahi K, Machii N, Iseki K, Satoh H, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Shibagaki Y, Kasahara M, Watanabe T, Shimabukuro M
    • Journal Title

      Sci Rep

      Volume: 11(1) Issue: 1 Pages: 716-716

    • DOI

      10.1038/s41598-020-80572-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11131, KAKENHI-PROJECT-17K00924, KAKENHI-PROJECT-20K11654
  • [Journal Article] Association of Local Epicardial Adipose Tissue Depots and Left Ventricular Diastolic Performance in Patients With Preserved Left Ventricular Ejection Fraction2020

    • Author(s)
      Maimaituxun Gulinu、Yamada Hirotsugu、Fukuda Daiju、Yagi Shusuke、Kusunose Kenya、Hirata Yukina、Nishio Susumu、Soeki Takeshi、Masuzaki Hiroaki、Sata Masataka、Shimabukuro Michio
    • Journal Title

      Circ J

      Volume: 84 Issue: 2 Pages: 203-216

    • DOI

      10.1253/circj.CJ-19-0793

    • NAID

      130007789877

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2020-01-24
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-19K08584, KAKENHI-PROJECT-20K08912, KAKENHI-PROJECT-19H03654
  • [Journal Article] Levels of Adiponectin Expression in Peri-Renal and Subcutaneous Adipose Tissue and Its Determinants in Human Biopsied Samples2020

    • Author(s)
      Maimaituxun Gulinu、Fukuda Daiju、Izaki Hirofumi、Hirata Yoichiro、Kanayama Hiro-omi、Masuzaki Hiroaki、Sata Masataka、Shimabukuro Michio
    • Journal Title

      Frontiers in Endocrinology

      Volume: 10 Pages: 897-897

    • DOI

      10.3389/fendo.2019.00897

    • NAID

      120006953545

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08584, KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-20K08912, KAKENHI-PROJECT-19H03654
  • [Journal Article] Walking Speed is the Sole Determinant Criterion of Sarcopenia of Mild Cognitive Impairment in Japanese Elderly Patients with Type 2 Diabetes Mellitus2020

    • Author(s)
      Machii Noritaka、Kudo Akihiro、Saito Haruka、Tanabe Hayato、Iwasaki Mariko、Hirai Hiroyuki、Masuzaki Hiroaki、Shimabukuro Michio
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 7 Pages: 2133-2133

    • DOI

      10.3390/jcm9072133

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08912, KAKENHI-PROJECT-17K00924
  • [Journal Article] New risk prediction model of coronary heart disease in participants with and without diabetes: Assessments of the Framingham risk and Suita scores in 3-year longitudinal database in a Japanese population2019

    • Author(s)
      Hirai Hiroyuki、Asahi Koichi、Yamaguchi Satoshi、Mori Hirotaka、Satoh Hiroaki、Iseki Kunitoshi、Moriyama Toshiki、Yamagata Kunihiro、Tsuruya Kazuhiko、Fujimoto Shouichi、Narita Ichiei、Konta Tsuneo、Kondo Masahide、Shibagaki Yugo、Kasahara Masato、Watanabe Tsuyoshi、Shimabukuro Michio
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 2813-2813

    • DOI

      10.1038/s41598-019-39049-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08860, KAKENHI-PROJECT-16K09363, KAKENHI-PROJECT-16K01823
  • [Journal Article] Low fasting plasma glucose level as a predictor of new-onset diabetes mellitus on a large cohort from a Japanese general population2018

    • Author(s)
      Ogata Emi、Asahi Koichi、Yamaguchi Satoshi、Iseki Kunitoshi、Sato Hiroaki、Moriyama Toshiki、Yamagata Kunihiro、Tsuruya Kazuhiko、Fujimoto Shouichi、Narita Ichiei、Konta Tsuneo、Kondo Masahide、Shibagaki Yugo、Kasahara Masato、Watanabe Tsuyoshi、Shimabukuro Michio
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 13927-13927

    • DOI

      10.1038/s41598-018-31744-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K02242, KAKENHI-PROJECT-16K08860, KAKENHI-PROJECT-16K09363
  • [Journal Article] Local Thickness of Epicardial Adipose Tissue Surrounding the Left Anterior Descending Artery Is a Simple Predictor of Coronary Artery Disease ― New Prediction Model in Combination With Framingham Risk Score ―2018

    • Author(s)
      Maimaituxun Gulinu、Shimabukuro Michio、Fukuda Daiju、Yagi Shusuke、Hirata Yukina、Iwase Takashi、Takao Shoichiro、Matsuura Tomomi、Ise Takayuki、Kusunose Kenya、Tobiume Takeshi、Yamaguchi Koji、Yamada Hirotsugu、Soeki Takeshi、Wakatsuki Tetsuzo、Harada Masafumi、Sata Masataka
    • Journal Title

      Circ J

      Volume: 82 Issue: 5 Pages: 1369-1378

    • DOI

      10.1253/circj.CJ-17-1289

    • NAID

      130006725981

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05299, KAKENHI-PROJECT-16K09517, KAKENHI-PROJECT-16K01823
  • [Journal Article] Effect of the Epicardial Adipose Tissue Volume on the Prevalence of Paroxysmal and Persistent Atrial Fibrillation2018

    • Author(s)
      Oba Kageyuki、Maeda Minetaka、Maimaituxun Gulinu、Yamaguchi Satoshi、Arasaki Osamu、Fukuda Daiju、Yagi Shusuke、Hirata Yukina、Nishio Susumu、Iwase Takashi、Takao Shoichiro、Kusunose Kenya、Yamada Hirotsugu、Soeki Takeshi、Wakatsuki Tetsuzo、Harada Masafumi、Masuzaki Hiroaki、Sata Masataka、Shimabukuro Michio
    • Journal Title

      Circ J

      Volume: 82 Issue: 7 Pages: 1778-1787

    • DOI

      10.1253/circj.CJ-18-0021

    • NAID

      130007410632

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2018-06-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05299, KAKENHI-PROJECT-16K09517, KAKENHI-PROJECT-17K09839, KAKENHI-PROJECT-16K01823
  • [Journal Article] Usefulness of Epicardial Adipose Tissue Volume to Predict Recurrent Atrial Fibrillation After Radiofrequency Catheter Ablation2018

    • Author(s)
      Maeda Minetaka、Oba Kageyuki、Yamaguchi Satoshi、Arasaki Osamu、Sata Masataka、Masuzaki Hiroaki、Shimabukuro Michio
    • Journal Title

      The American Journal of Cardiology

      Volume: 122 Issue: 10 Pages: 1694-1700

    • DOI

      10.1016/j.amjcard.2018.08.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05299, KAKENHI-PROJECT-17K09839, KAKENHI-PROJECT-16K01823
  • [Journal Article] Plasma brain natriuretic peptide levels are elevated in patients with cancer.2017

    • Author(s)
      Bando S, Soeki T, Matsuura T, Tobiume T, Ise T, Kusunose K, Yamaguchi K, Yagi S, Fukuda D, Iwase T, Yamada H, Wakatsuki T, Shimabukuro M, Muguruma N, Takayama T, Kishimoto I, Kangawa K, Sata M.
    • Journal Title

      PLoSOne

      Volume: 12 Issue: 6 Pages: e0178607-e0178607

    • DOI

      10.1371/journal.pone.0178607

    • NAID

      120006534961

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16K09517
  • [Journal Article] Gender-linked impact of epicardial adipose tissue volume in patients who underwent coronary artery bypass graft surgery or non-coronary valve surgery.2017

    • Author(s)
      Maimaituxun G, Shimabukuro M, Salim HM, Tabata M, Yuji D, Morimoto Y, Akasaka T, Matsuura T, Yagi S, Fukuda D, Yamada H, Soeki T, Sugimoto T, Tanaka M, Takanashi S, Sata M.
    • Journal Title

      PLoSOne

      Volume: 12 Issue: 6 Pages: e0177170-e0177170

    • DOI

      10.1371/journal.pone.0177170

    • NAID

      120006534964

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16K09517
  • [Journal Article] Teneligliptin, a dipeptidyl peptidase-4 inhibitor, attenuated pro-inflammatory phenotype of perivascular adipose tissue and inhibited atherogenesis in normoglycemic apolipoprotein-E-deficient mice.2017

    • Author(s)
      Hotimah Masdan Salim, Daiju Fukuda, Yasutomi Higashikuni, Kimie Tanaka, Yoichiro Hirata, Shusuke Yagi, Takeshi Soeki, Michio Shimabukuro, Masataka Sata.
    • Journal Title

      Vascular Pharmacology

      Volume: 印刷中 Pages: 19-25

    • DOI

      10.1016/j.vph.2017.03.003

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461141, KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16K09517
  • [Journal Article] Echocardiographic Epicardial Adipose Tissue Thickness Is Associated with Symptomatic Coronary Vasospasm during Provocative Testing.2017

    • Author(s)
      Nishio S, Kusunose K, Yamada H, Hirata Y, Ise T, Yamaguchi K, Yagi S, Soeki T, Wakatsuki T, Shimabukuro M, Sata M.
    • Journal Title

      J Am Soc Echocardiogr

      Volume: 30 Issue: 10 Pages: 1021-1027

    • DOI

      10.1016/j.echo.2017.06.024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16H05299
  • [Journal Article] α-Glucosidase inhibitor miglitol attenuates glucose fluctuation, heart rate variability and sympathetic activity in patients with type 2 diabetes and acute coronary syndrome: a multicenter randomized controlled (MACS) study2017

    • Author(s)
      Shimabukuro M, Tanaka A, Sata M, Dai K, Shibata Y, Inoue Y, Ikenaga H, Kishimoto S, Ogasawara K, Takashima A, Niki T, Arasaki O, Oshiro K, Mori Y, Ishihara M, Node K
    • Journal Title

      Cardiovascular Diabetology

      Volume: 16 Issue: 1 Pages: 86-86

    • DOI

      10.1186/s12933-017-0571-1

    • NAID

      120006937640

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16H05299
  • [Journal Article] Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue2016

    • Author(s)
      Nishimoto S, Fukuda D, Higashikuni Y, Tanaka K, Hirata Y, Murata C, Kim-Kaneyama JR, Sato F, Bando M, Yagi S, Soeki T, Hayashi T, Imoto I, Sakaue H, Shimabukuro M, Sata M.
    • Journal Title

      Sci Adv.

      Volume: 2(3) Issue: 3

    • DOI

      10.1126/sciadv.1501332

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-25460369, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-16H05299, KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16K09517, KAKENHI-PROJECT-16K09753
  • [Journal Article] The pathophysiological role of oxidized cholesterols in epicardial fat accumulation and cardiac dysfunction: a study in swine fed a high caloric diet with an inhibitor of intestinal cholesterol absorption, ezetimibe.2016

    • Author(s)
      Shimabukuro M, Okawa C, Yamada H, Yanagi S, Uematsu E, Sugasawa N, Kurobe H, Hirata Y, Kim-Kaneyama JR, Lei XF, Takao S, Tanaka Y, Fukuda D, Yagi S, Soeki T, Kitagawa T, Masuzaki H, Sato M, Sata M.
    • Journal Title

      J Nutr Biochem.

      Volume: 35 Pages: 66-73

    • DOI

      10.1016/j.jnutbio.2016.05.010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-26860588, KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16K09517, KAKENHI-PROJECT-16K10553, KAKENHI-PROJECT-16K15632
  • [Journal Article] Glycemic control with ipragliflozin, a novel selective SGLT2 inhibitor, ameliorated endothelial dysfunction in streptozotocin-induced diabetic mouse2016

    • Author(s)
      Salim HM, Fukuda D, Yagi S, Soeki T, Shimabukuro M, Sata M
    • Journal Title

      Front Cardiovasc Med

      Volume: 3 Pages: 43-43

    • DOI

      10.3389/fcvm.2016.00043

    • NAID

      120006937668

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05299, KAKENHI-PROJECT-16K01823, KAKENHI-PROJECT-16K09517
  • [Journal Article] 玄米と高脂肪食2015

    • Author(s)
      益崎 裕章、小塚 智沙代、田仲 秀明、島袋 充生
    • Journal Title

      Annual Review 糖尿病・代謝・内分泌2015

      Volume: 1 Pages: 38-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] Gamma-oryzanol prorects pancreatic β-cell against endoplasmic reticulum stress in male mice2015

    • Author(s)
      C.Kozuka,S.Sunagawa,R.Ueda,S.M.Higa,H.Tanaka,C.Shimizu-Okabe,S.Ishiuchi,C.Takayama,M.Matsushita,M.Tsutsui,J.Miyazaki,S.Oyadomari,M.Shimabukuro,H.Masuzaki
    • Journal Title

      Endocrinology

      Volume: 156 Pages: 1242-1250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] 食欲は操れるのか?食欲を調節する食品は存在するのか インクレチン関連薬は減量に有効か2014

    • Author(s)
      益崎 裕章、小塚 智沙代、島袋 充生
    • Journal Title

      メタボリックドミノに挑む 俺流処方 糖尿病・腎・内分泌疾患

      Volume: 2 Pages: 83-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] 慢性的高脂肪食習慣に伴う視床下部の炎症と小胞体ストレス2014

    • Author(s)
      益崎 裕章、小塚 智沙代、中山 良朗、島袋 充生
    • Journal Title

      (特集:臓器間 代謝ネットワークと糖尿病)Diabetes Frontier

      Volume: 25 Pages: 51-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] Association of lower limb muscle mass and energy expenditure with visceral fat mass in healthy men2014

    • Author(s)
      Yagi S, Kadota M, Aihara K, Nishikawa K, Hara T, Ise T, Ueda Y, Iwase T, Akaike M, Shimabukuro M, Katoh S, Sata M.
    • Journal Title

      Diabetology & metabolic syndrome

      Volume: 6 Issue: 1 Pages: 27-27

    • DOI

      10.1186/1758-5996-6-27

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591046, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-25461131
  • [Journal Article] αグルコシダーゼ阻害剤以外の薬物療法の可能性2014

    • Author(s)
      益崎 裕章、島袋 充生
    • Journal Title

      (特集:境界型糖尿病の診断と治療管理)月刊糖尿病

      Volume: 6 Pages: 73-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] Azilsartan,au angitensin ll receptor blocker,restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser1177/Thr497 of endothelial nitric oxide synthase in diabetic mice2014

    • Author(s)
      S.Matsumoto,M.Shimabukuro,D.Fukuda,T.Soeki,K.Yamakawa,H.Masuzaki,M.Sata
    • Journal Title

      Cardiovasc Diabetology

      Volume: 13 Pages: 30-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] Azilsartan, an angiotensin II type 1 receptor blocker, restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser1177/Thr497 of endothelial nitric oxide synthase in diabetic mice.2014

    • Author(s)
      Matsumoto S, Shimabukuro M, Fukuda D, Soeki T, Yamakawa K, Masuzaki H, Sata M.
    • Journal Title

      Cardiovasc Diabetol

      Volume: 13 Issue: 1 Pages: 30-30

    • DOI

      10.1186/1475-2840-13-30

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24591063, KAKENHI-PROJECT-25293184
  • [Journal Article] Effects of brown rice diet on visceral obesity and endothelial function: the BRAVO study.2014

    • Author(s)
      1. Shimabukuro M, Higa M, Kinjo R, Yamakawa K, Tanaka H, Kozuka C, Yabiku K, Taira S, Sata M, Masuzaki H.
    • Journal Title

      Br J Nutr

      Volume: 111 Issue: 2 Pages: 310-320

    • DOI

      10.1017/s0007114513002432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24591063, KAKENHI-PROJECT-24591338, KAKENHI-PROJECT-25293184
  • [Journal Article] MicroRNA-378 Regulates Adiponectin Expression in Adipose Tissue: A New Plausible Mechanism.2014

    • Author(s)
      Ishida M, Shimabukuro M, Yagi S, Nishimoto S, Kozuka C, Fukuda D, Soeki T, Masuzaki H, Tsutsui M, Sata M
    • Journal Title

      PLoS One

      Volume: 9 Issue: 11 Pages: e111537-e111537

    • DOI

      10.1371/journal.pone.0111537

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J09668, KAKENHI-PROJECT-24591338, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-25461131
  • [Journal Article] 沖縄クライシスの現状と今後の課題2014

    • Author(s)
      益崎 裕章、田仲 秀明、上江冽 良尚、島袋 充生
    • Journal Title

      日本臨牀 増刊号:最新 肥満症学:基礎・臨床研究の最前線

      Volume: 72 Pages: 675-681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] Association of borderline ankle-brachial index with mortality and the incidence of peripheral artery disease in diabetic patients.2014

    • Author(s)
      Natsuaki C, Inoguchi T, Maeda Y, Yamada T, Sasaki S, Sonoda N, Shimabukuro M, Nawata H, Takayanagi R.
    • Journal Title

      Atherosclerosis

      Volume: 234 Issue: 2 Pages: 360-365

    • DOI

      10.1016/j.atherosclerosis.2014.03.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314
  • [Journal Article] Epicardial adipose tissue volume and adipocytokine imbalance are strongly linked to human coronary atherosclerosis.2013

    • Author(s)
      Shimabukuro M et al.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 33 Pages: 1077-1084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314
  • [Journal Article] Ectopic Fat Deposition and Global Cardiometabolic Risk: New Paradigm in Cardiovascular Medicine2013

    • Author(s)
      M. Shimabukuro, C. Kozuka, S.Taira, K.Yabiku, N. Dagvasumberel, M. Ishida, S.Matsumoto, S.Yagi, D. Fukuda, K. Yamakawa, M. Higa, T. Soeki, H. Yoshida, H. Masuzaki, M. Sata.
    • Journal Title

      J Med Invest

      Volume: 60 Pages: 1-14

    • NAID

      130004465276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] Lipid deposition in various sites of skeletal muscle and liver shows correlation with visceral fat accumulation in male patients with metabolic syndrome.2013

    • Author(s)
      Taira S, Shimabukuro M, Higa M, Yabiku K, Kozuka C, Ueda R, Sunagawa S, Ohshiro Y, Doi M, Nanba T, Kawamoto E, Nakayama Y, Nakamura H, Iha T, Nakachi S, Tomoyose T, Ikema T, Yamakawa K, Masuzaki H.
    • Journal Title

      Intern Med

      Volume: 52 Pages: 1561-1571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314
  • [Journal Article] Ectopic fat deposition and global cardiometabolic risk: New paradigm in cardiovascular medicine.2013

    • Author(s)
      Shimabukuro M et al.
    • Journal Title

      J Med Invest.

      Volume: 60 Pages: 1-14

    • NAID

      130004465276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314
  • [Journal Article] Miglitol,α-glycosidase inhibitor, reduces visceral fat accumulation and cardiovascular risk factors in subjects with the metabolic syndrome2013

    • Author(s)
      Shimabukuro M, et al
    • Journal Title

      Int J Cardiol

      Volume: 167 Issue: 5 Pages: 2108-2113

    • DOI

      10.1016/j.ijcard.2012.05.109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24591063, KAKENHI-PROJECT-24591338, KAKENHI-PROJECT-24659392, KAKENHI-PROJECT-25670390
  • [Journal Article] Epicardial adipose tissue volume and adipocytokine imbalance are strongly linked to human coronary atherosclerosis2013

    • Author(s)
      M. Shimabukuro, Y. Hirata, M. Tabata, M. Dagvasumberel, H. Sato, H. Kurobe, D. Fukuda, T. Soeki, T. Kitagawa, S. Takanashi, M. Sata
    • Journal Title

      Arterioscler. Thromb. Vasc. Biol.

      Volume: 33 Issue: 5 Pages: 1077-1084

    • DOI

      10.1161/atvbaha.112.300829

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21117007, KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24390331, KAKENHI-PROJECT-24659392, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-25670390
  • [Journal Article] Natural Food based Novel Approach toward Prevention and Treatment of Obesity and Type 2 Diabetes: Recent Studies on Brown Rice and γ-Oryzanol2013

    • Author(s)
      C. Kozuka, K.Yabiku, C.Takayama, M.Matsushita, M.Shimabukuro, H. Masuzaki (corresponding author)
    • Journal Title

      Obes Res Clin Pract

      Volume: 7 Issue: 3 Pages: e165-e172

    • DOI

      10.1016/j.orcp.2013.02.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] Defects of vascular nitric oxide bioavailability in subjects with impaired glucose tolerance: A potential link to insulin resistance.2013

    • Author(s)
      Michio Shimabukuro
    • Journal Title

      International Journal of Cardiology

      Volume: in press Issue: 1 Pages: 298-300

    • DOI

      10.1016/j.ijcard.2012.09.194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-22590503, KAKENHI-PROJECT-23500990, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24659392, KAKENHI-PROJECT-25670390
  • [Journal Article] Lipid deposition in various sites of the skeletal muscles and liver exhibits a positive correlation with visceral fat accumulation in middle-aged Japanese men with metabolic syndrome.2013

    • Author(s)
      Taira S, Shimabukuro M, Higa M, Yabiku K, Kozuka C, Ueda R, Sunagawa S, Ohshiro Y, Doi M, Nanba T, Kawamoto E, Nakayama Y, Nakamura H, Iha T, Nakachi S, Tomoyose T, Ikema T, Yamakawa K, Masuzaki H.
    • Journal Title

      Intern Med.

      Volume: 52 Pages: 1561-71

    • NAID

      130003365715

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Journal Article] Role of macrophage-derived hypoxia-inducible factor (HIF)-1α as a mediator of vascular remodelling2013

    • Author(s)
      Nakayama T, Kurobe H, Sugasawa N, Kinoshita H, Higashida M, Matsuoka Y, Yoshida Y, Hirata Y, Sakata M, Maxfield M, Shimabukuro M, Takahama Y, Sata M, Tamaki T, Kitagawa T, Tomita S.
    • Journal Title

      Cardiovasc Res

      Volume: 99 Issue: 4 Pages: 705-715

    • DOI

      10.1093/cvr/cvt146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249025, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-23592040, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-24390331, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24592068, KAKENHI-PROJECT-25670390
  • [Journal Article] Lipid Deposition in Various Sites of Skeletal Muscle and Liver Exhibits a Positive Correlation with Visceral Fat Accumulation in Middle-Aged Japanese Men with Metabolic Syndrome2013

    • Author(s)
      S. Taira, M. Shimabukuro, M. Higa, K. Yabiku, C. Kozuka, R. Ueda, S. Sunagawa, Y. Ohshiro, M. Doi, E. Kawamoto, Y. Nakayama, H. Nakamura, T. Iha, S. Nakachi, T. Tomoyose, T. Ikema, K. Yamakawa, H. Masuzaki (corresponding author)
    • Journal Title

      Intern Med

      Volume: 52 Pages: 1561-1571

    • NAID

      130003365715

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591338
  • [Journal Article] Protective effects of selective mineralocorticoid receptor antagonist against aortic aneurysm progression in a novel murine model.2013

    • Author(s)
      Kurobe H, Hirata Y, Matsuoka Y, Sugasawa N, Higashida M, Nakayama T, Maxfield MW, Yoshida Y, Shimabukuro M, Kitagawa T, Sata M.
    • Journal Title

      J Surg Res

      Volume: 185 Issue: 1 Pages: 455-462

    • DOI

      10.1016/j.jss.2013.05.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-23592040, KAKENHI-PROJECT-24390331, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-25670390
  • [Journal Article] – Unsolved Questions –2012

    • Author(s)
      Shimabukuro, M, et al
    • Journal Title

      Circ J

      Volume: 76 Issue: 3 Pages: 593-595

    • DOI

      10.1253/circj.CJ-12-0062

    • NAID

      10030129723

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-23659420, KAKENHI-PROJECT-24591338, KAKENHI-PROJECT-24659392
  • [Journal Article] Eicosapentaenoic acid supplementation changes fatty acid composition and corrects endothelial dysfunction in hyperlipidemic patients.2012

    • Author(s)
      Ken Yamakawa
    • Journal Title

      Cardiology Research and Practice

      Volume: 2012 Pages: 754181-754181

    • DOI

      10.1155/2012/754181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-22590503, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24591063, KAKENHI-PROJECT-24591338, KAKENHI-PROJECT-24659392
  • [Journal Article] Activation of AMPK-Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects2012

    • Author(s)
      Shiota A, Shimabukuro M, Fukuda D, Soeki T, Sato H, Uematsu E, Hirata Y, Kurobe H, Sakaue H, Nakaya Y, Masuzaki H, Sata M
    • Journal Title

      Eur J Pharmacol

      Volume: 692 Issue: 1-3 Pages: 84-90

    • DOI

      10.1016/j.ejphar.2012.07.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24591333, KAKENHI-PROJECT-24591338, KAKENHI-PROJECT-24659392, KAKENHI-PUBLICLY-23126520
  • [Journal Article] Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice2012

    • Author(s)
      Shiota A, Shimabukuro M, Fukuda D, Soeki T, Sato H, Uematsu E, Hirata Y, Kurobe H, Maeda N, Sakaue H, Masuzaki H, Shimomura I, Sata M.
    • Journal Title

      Cardiovascular Diabetol.

      Volume: 11 Issue: 1 Pages: 139-139

    • DOI

      10.1186/1475-2840-11-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-22590979, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24591333, KAKENHI-PROJECT-24591338, KAKENHI-PROJECT-24659392, KAKENHI-PUBLICLY-23126520
  • [Journal Article] Brown Rice and Its Component, γ-Oryzanol, Attenuate the Preference for High-Fat Diet by Decreasing Hypothalamic Endoplasmic Reticulum Stress in Mice2012

    • Author(s)
      Kozuka C, Oyadomari S
    • Journal Title

      Diabetes

      Volume: 61 Issue: 12 Pages: 3084-93

    • DOI

      10.2337/db11-1767

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390061, KAKENHI-PROJECT-23500413, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-23650481, KAKENHI-PROJECT-23659114, KAKENHI-PROJECT-24591063, KAKENHI-PROJECT-24591338, KAKENHI-PUBLICLY-24116519
  • [Journal Article] Impaired glucose tolerance, but not impaired fasting glucose, underlies left ventricular diastolic dysfunction.2011

    • Author(s)
      Shimabukuro M, et al.
    • Journal Title

      Diabetes Care

      Volume: 34 Pages: 686-690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] Impaired glucose tolerance, but not impaired fasting glucose, underlies left ventricular diastolic dysfunction.2011

    • Author(s)
      Shimabukuro M, Higa N, Asahi T, Yamakawa K, Oshiro Y, Higa M, Masuzaki H.
    • Journal Title

      Diabetes Care. 34

      Pages: 686-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590542
  • [Journal Article] Impaired glucose tolerance, but not impaired fasting glucose, underlies left ventricular diastolic dysfunction2011

    • Author(s)
      Shimabukuro M, et al
    • Journal Title

      Diabetes Care

      Volume: 34 Issue: 3 Pages: 686-690

    • DOI

      10.2337/dc10-1141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314
  • [Journal Article] Distinct effects of pitavastatin and atorvastatin on lipoprotein subclasses in patients of type 2 diabetes mellitus2011

    • Author(s)
      Shimabukuro M, et al
    • Journal Title

      Diabetic Med

      Volume: 28 Issue: 7 Pages: 856-864

    • DOI

      10.1111/j.1464-5491.2011.03240.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591314
  • [Journal Article] Impaired glucose tolerance, but not impaired fasting glucose, underlies left ventricular diastolic dysfunction.2011

    • Author(s)
      Shimabukuro M, et al.
    • Journal Title

      Diabetes Care

      Volume: 34 Pages: 686-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590542
  • [Journal Article] Distinct effects of pitavastatin and atorvastatin on lipoprotein subclasses in patients with Type 2 diabetes mellitus. Epub ahead of print2011

    • Author(s)
      Shimabukuro M, Higa M, Tanaka H, Shimabukuro T, Yamakawa K, Masuzaki H.
    • Journal Title

      Diabet Med.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590542
  • [Journal Article] Distinct effects of pitavastatin and atorvastatin on lipoprotein subclasses in patients of type 2 diabetes mellitus.2011

    • Author(s)
      Shimabukuro M, Higa M, Tanaka H, Shimabukuro T, Yamakawa K, Masuzaki H
    • Journal Title

      Diabetic Med 28

      Pages: 856-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] Impaired glucose tolerance, but not impaired fasting glucose, underlies left ventricular diastolic dysfunction.2011

    • Author(s)
      Shimabukuro M
    • Journal Title

      Diabetes Care

      Volume: 34

    • Data Source
      KAKENHI-PROJECT-23591314
  • [Journal Article] Impaired glucose tolerance, but not impaired fasting glucose, underlies left ventricular diastolic dysfunction.2011

    • Author(s)
      Shimabukuro M, Higa N, Asahi T, PhD, Yamakawa K, Oshiro Y, Higa M, Masuzaki H.
    • Journal Title

      Diabetes Care 34

      Pages: 686-690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] Distinct effects of pitavastatin and atorvastatin on lipoprotein subclasses in patients of type 2 diabetes mellitus.2011

    • Author(s)
      Shimabukuro M, et al.
    • Journal Title

      Diabetic Medicine

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] Human Catalase Gene is Regulated by Peroxisome Proliferator Activated Receptor-gamma through a Response Element Distinct from That of Mouse.2010

    • Author(s)
      Okuno Y, Matsuda M, Miyata Y, Fukuhara A, Komuro R, Shimabukuro M, Shimomura I.
    • Journal Title

      Endocr J. 57

      Pages: 303-309

    • NAID

      10029584294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] J Metab Synd2010

    • Author(s)
      Yabiku K, Ohshiro Y, Sunagawa S, Kozuka C, Taira S, Ueda R, Nakamoto K, Iwabuchi K, Yonaha M, Yamakawa K, Higa M, Shimabukuro M, Masuzaki H
    • Journal Title

      J Metab Synd

      Volume: 7 Pages: 26-30

    • Data Source
      KAKENHI-PROJECT-22591014
  • [Journal Article] Cardiac adiposity and global cardiometabolic risk.2009

    • Author(s)
      Shimabukuro M.
    • Journal Title

      Circ J. 73

      Pages: 27-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance.2009

    • Author(s)
      Tabata M, Kadomatsu T, Fukuhara S, Miyata K, Ito Y, Endo M, Urano T, Zhu HJ, Tsukano H, Tazume H, Kaikita K, Miyashita K, Iwawaki T, Shimabukuro M, Sakaguchi K, Ito T, Nakagata N, Yamada T, Katagiri H, Kasuga M, Ando Y, Ogawa H, Mochizuki N, Itoh H, Suda T, Oike Y.
    • Journal Title

      Cell Metab. 10

      Pages: 178-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] Adipose expression of catalase is regulated via a novel remote PPAR γ-responsive region.2008

    • Author(s)
      Okuno Y 、Matsuda M 、Kobayashi H 、Nakamura H 、Suzuki E 、Morita K 、Fukuhara A、Komuro R、Shimabukuro M、 Shimomura I.
    • Journal Title

      Biochem Biophys Res Commun 366

      Pages: 698-704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] Adipose expression of catalase is regulated via a novel remote PPAR γ-responsive region.2008

    • Author(s)
      Okuno Y, Matsuda M, Kobayashi H, Nakamura H, Suzuki E, Morita K, Fukuhara A, Komuro R, Shimabukuro M, Shimomura I.
    • Journal Title

      Biochem Biophys Res Commun 366

      Pages: 698-704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] High prevalence of peripheral arterial disease diagnosed by low ankle-brachial index in Japanese patients with diabetes : The Kyushu Prevention Study for Atherosclerosis.2008

    • Author(s)
      Maeda Y, Inoguchi T, Tsubouchi H, Sawada F, Sasaki S, Fujii M, Saito R, Yanase T, Shimabukuro M, Nawata H, Takayanagi R.
    • Journal Title

      Diabetes Res Clin Pract 82

      Pages: 378-382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] High prevalence of peripheral arterial disease diagnosed by low ankle-brachial index in Japanese patients with diabetes: The Kyushu Prevention study for Atherosclerosis.2008

    • Author(s)
      Maeda Y, Inoguchi T, Tsubouchi H, Sawada F, Sasaki S, Fujii M, Saito R, Yanase T, Shimabukuro M, Nawata H, Takayanagi R.
    • Journal Title

      Diabetes Res Clin Pract 82

      Pages: 378-382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Journal Article] Effects of dietary composition on postprandial endothelial function and adiponectin concentrations in healthy humans: a crossover controlled study2007

    • Author(s)
      Shimabukuro M, Chinen I, Higa N, Takasu N, Yamakawa K, Ueda S
    • Journal Title

      Am J Clin Nutr 86

      Pages: 923-928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390303
  • [Journal Article] Effects of dietary composition on postprandial endothelial function and adiponectin concentrations in healthy humans : a crossover controlled study2007

    • Author(s)
      Shimabukuro M, Chinen I, Higa N, Takasu N, Yamakawa K, Ueda S
    • Journal Title

      Am J Clin Nutr 86

      Pages: 923-928

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390303
  • [Journal Article] Effects of dietary composition on postprandial endothelial function and adiponectin concentrations in healthy humans: a crossover controlled study2007

    • Author(s)
      Shimabukuro M, Chinen I, Higa N, Takasu N, Yamakawa K, Ueda S.
    • Journal Title

      Am J Clin Nutr 86

      Pages: 923-928

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390303
  • [Journal Article] Serum C-Reactive Protein and Its Relation to Cardiovascular Risk Factors and Adipocytokines in Japanese Children.2006

    • Author(s)
      Yoshida T, Kaneshi T, Shimabukuro M, Sunagawa M, Ohshiro T, Asato Y, Ohta T
    • Journal Title

      J Clin Endocrinol Metab 91

      Pages: 2133-2137

    • Data Source
      KAKENHI-PROJECT-17390303
  • [Journal Article] Relationship between lipid abnormalities and insulin resistance in Japanese school children.2006

    • Author(s)
      Asato Y, Katsuren K, Ohshiro T, Kikawa K, Shimabukuro T, Ohta T
    • Journal Title

      Arterioscler Thromb Vasc Biol. 26

      Pages: 2781-2786

    • Data Source
      KAKENHI-PROJECT-17390303
  • [Journal Article] メタボリックシンドロームにおける血管内皮機能:脂肪毒性が関与するのか?2005

    • Author(s)
      島袋充生, 比嘉南夫, 知念一郎, 高須信行, 山川研, 田川辰也, 植田真一郎, 松崎俊博, 野口克彦
    • Journal Title

      血圧 (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 遊離脂肪酸とインスリン抵抗性:脂肪毒性2005

    • Author(s)
      島袋充生
    • Journal Title

      治療学 (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Protein kinase B/Akt signaling is required for palmitate-induced β-cell lipotoxicity.2005

    • Author(s)
      Higa M, Shimabukuro S, Shimajiri Y, Takasu N, Shinjyo T, Inaba T.
    • Journal Title

      Diab Obes Metab. (in press)

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Protein kinase B/Akt signaling is required for palmitate-induced β-cell lipotoxicity.2005

    • Author(s)
      Higa M, Shimabukuro S, Shimajiri Y, Takasu N, Shinjyo T, Inaba T.
    • Journal Title

      Diab Obes Metab.

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Electrophysiologic Characteristics of Atrial Myocytes in Levo-thyroxine-Treated Rats.2005

    • Author(s)
      Sunagawa M, Yamakawa M, Shimabukuro M, Higa N, Takasu N, Kosugi T.
    • Journal Title

      Thyroid 15

      Pages: 3-11

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] インスリン抵抗性と脂質代謝異常2005

    • Author(s)
      島袋充生
    • Journal Title

      総合臨床 54巻

      Pages: 1615-1621

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 脂肪毒性と糖尿病:日本人に多い肥満しているがインスリン分泌が低下していく現象とは?2004

    • Author(s)
      島袋充生
    • Journal Title

      治療

      Pages: 2937-2942

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Cutting Edge:遊離脂肪酸2004

    • Author(s)
      島袋充生
    • Journal Title

      Medical Science Digest 33

      Pages: 44-46

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Increased oxidative stress in obesity and its impact on metabolic syndrome.2004

    • Author(s)
      Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I.
    • Journal Title

      J Clin Invest 114

      Pages: 1752-1761

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 血管内皮障害と治療効果:肥満2004

    • Author(s)
      島袋充生
    • Journal Title

      治療学 38・8

      Pages: 55-59

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 脂質代謝とレニン・アンジオテンシン・アルドステロン系2004

    • Author(s)
      島袋充生
    • Journal Title

      Angiotensin Research 1・3

      Pages: 25-30

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 日本人のメタボリックシンドロームとは-脂肪毒性2004

    • Author(s)
      島袋充生
    • Journal Title

      Progress in Medicine 24巻9号

      Pages: 96-99

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 肥満症とメタボリック症候群2004

    • Author(s)
      島袋充生
    • Journal Title

      日本医事新報

      Pages: 89-89

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Fluvastatin Improves Endothelial Dysfunction in Overweight Post-Menopausal Women through Small Dense LDL Reduction.2004

    • Author(s)
      Shimabukuro M, Higa N, Asahi T, Oshiro Y, Takasu N.
    • Journal Title

      Metabolism 53

      Pages: 733-739

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] メタボリックシンドロー厶の中での肥満の位置づけ2004

    • Author(s)
      島袋充生
    • Journal Title

      The Lipid 15・4(in press)

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 肥満症とメタボリック症候群2004

    • Author(s)
      島袋充生
    • Journal Title

      日本医事新報 4206号

      Pages: 89-89

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 脂肪毒性によるインスリン分泌障害2004

    • Author(s)
      島袋充生
    • Journal Title

      Medical Science Digest 30

      Pages: 272-275

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 高脂肪酸血症と膵β細胞機能2004

    • Author(s)
      島袋充生
    • Journal Title

      Diabetes Frontier

      Pages: 459-464

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] メタボリックシンドロームの真実と実際:脂肪毒性と糖尿病:日本人に多い肥満しているがインスリン分泌が低下していく現象とは?2004

    • Author(s)
      島袋充生
    • Journal Title

      治療 (in press)

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Cutting Edge:遊離脂肪酸2004

    • Author(s)
      島袋充生
    • Journal Title

      Medical Science Digest 30・2

      Pages: 44-46

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Increased oxidative stress in obesity and its impact on metabolic syndrome.2004

    • Author(s)
      Furukawa S, Fujita T, Shimabukuro M, Iwali M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I.
    • Journal Title

      J Clin Invest 114

      Pages: 1752-1761

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Cilostazol, a phosphodiesterase inhibitor, reduces microalbuminuria in the insulin-resistant Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.2004

    • Author(s)
      Tohma T, Shimabukuro M, Oshiro Y, Yamakawa M, Shimajiri Y, Takasu N.
    • Journal Title

      Metabolism 2004

      Pages: 1405-1410

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Cilostazol, a phosphodiesterase inhibitor, reduces microalbuminuria in the insulin-resistant Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.2004

    • Author(s)
      Tohma T, Shimabukuro M, Oshiro Y, Yamakawa M, Shimajiri Y, Takasu N.
    • Journal Title

      Metabolism 53

      Pages: 1405-1410

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] A single dose of nateglinide improves postprandial endothelial dysfunction in type 2 diabetic patients.2004

    • Author(s)
      Shimabukuro M, Higa N, Takasu N, Tagawa T, Ueda S.
    • Journal Title

      Diabet Med 21

      Pages: 983-986

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Nitroglycerin spray rapidly improved the pain in a patient with chronic painful diabetic neuropathy.2004

    • Author(s)
      Higa M, Takasau N, Tamanaha T, Nakamura K, Shimabukuro M, Sasara T, Tawata M.
    • Journal Title

      Diabet Med 21

      Pages: 1053-1054

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] メタボリックシンドロームの中での肥満の位置づけ2004

    • Author(s)
      島袋充生
    • Journal Title

      The Lipid

      Pages: 194-200

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 脂質代謝とレニン・アンジオテンシン・アルドステロン系2004

    • Author(s)
      島袋充生
    • Journal Title

      Angiotensin Research

      Pages: 213-218

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 血管内皮障害と治療効果:肥満2004

    • Author(s)
      島袋充生
    • Journal Title

      治療学

      Pages: 903-907

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] A single dose of nateglinide improves postprandial endothelial dysfunction in type 2 diabetic patients.2004

    • Author(s)
      Shimabukuro M, Higa N, Takasu N, Tagawa T, Ueda S.
    • Journal Title

      Diabet Med 2004 21

      Pages: 983-986

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 高脂肪酸血症と膵β細胞機能2004

    • Author(s)
      島袋充生
    • Journal Title

      Diabetes Frontier 15・4

      Pages: 459-464

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 日本人のメタボリックシンドロームとは、脂肪毒性2004

    • Author(s)
      島袋充生
    • Journal Title

      Progress in Medicine (in press)

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 脂肪毒性によるインスリン分泌障害2004

    • Author(s)
      島袋充生
    • Journal Title

      Medical Science Digest 30・7

      Pages: 272-275

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 血管内皮依存性拡張反応に及ぼすPitavastatinの効果 インスリン抵抗性モデルにおける検討2003

    • Author(s)
      島袋充生, 比嘉南夫, 松崎俊博
    • Journal Title

      Therapeutic Research 24巻7号

      Pages: 1383-1389

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 血栓の後天的要因 糖尿病,高脂血症と動脈硬化2003

    • Author(s)
      島袋充生
    • Journal Title

      カレントテラピー 21巻・6号

      Pages: 542-546

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] 遊離脂肪酸の生理活性:脂肪毒性の基礎と臨床2003

    • Author(s)
      島袋充生
    • Journal Title

      Annual Review 内分泌,代謝

      Pages: 24-29

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Hypoadiponectinemia is closely linked to endothelial dysfunction in man.2003

    • Author(s)
      Shimabukuro M, Higa N, Asahi T, Oshiro Y, Takasu N, Tagawa T, Ueda S, Shimomura I, Funahashi T, Matsuzawa Y.
    • Journal Title

      J Clin Endocrinol Metab 88

      Pages: 3236-3240

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] PAX4 mutation (R121W) as a prodiabetic variant in Okinawans, Japan.2003

    • Author(s)
      Shimajiri Y, Shimabukuro M, Tomoyose T, Yogi H, Komiya I, Takasu N.
    • Journal Title

      Biochem Biophys Res Commun 302

      Pages: 342-344

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] メタボリック症候群における脂肪毒性の役割と分子標的2003

    • Author(s)
      島袋充生
    • Journal Title

      分子心血管病 4巻4号

      Pages: 385-392

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Hypoadiponectinemia is closely linked to endothelial dysfunction in man.2003

    • Author(s)
      Shimabukuro M, Higa N, Asahi T, Oshiro Y, Takasu N, Tagawa T, Ueda S, Shimomura I, Funahashi T, Matsuzawa Y.
    • Journal Title

      J Clin Endocrinol Metab. 88

      Pages: 3236-3240

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Hypoadiponectinemia is closely linked to endothelial dysfunction in man.2003

    • Author(s)
      Shimabukuro M, Higa N, Asahi T, Oshiro Y, Takasu N, Tagawa T, Ueda S, Shimomura I, Funahashi T, Matsuzawa Y
    • Journal Title

      J Clin Endocrinol Metab. 88

      Pages: 3236-3240

    • Data Source
      KAKENHI-PROJECT-14571103
  • [Journal Article] Protein kinase B/Akt signaling is required for palmitate-induced β-cell lipotoxicity.

    • Author(s)
      Higa M, Shimabukuro M, Shimajiri Y, Takasu N, Shinjyo T, Inaba T.
    • Journal Title

      Diab Obes Metab (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571103
  • [Presentation] 高脂肪食負荷db/dbマウスにおけるキサンチンオキシダーゼ阻害薬の血管内皮機能改善効果2013

    • Author(s)
      山川 研, 岩渕 敬子, 白倉 尚, 田村 みずほ, 比嘉 盛丈, 島袋 充生, 砂川 澄人, 屋比久 浩市, 小塚 智沙代, 植田 玲, 平良 伸一郎, 池間 朋己, 大城 譲, 益崎 裕章
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本市
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] Gender-based risk stratification of coronary artery disease in asymptomatic diabetic subjects : a multi-clinic study using multi-detector computed tomography2013

    • Author(s)
      Shimabukuro M, Saito T, Higa T, Nkamura K, Sata M
    • Organizer
      ESC Congress 2013
    • Place of Presentation
      Amsterdam RAI Exhibition and Convention Centre (Amsterdam, Netherlands)(一般演題)
    • Data Source
      KAKENHI-PROJECT-23591314
  • [Presentation] 玄米由来成分を活用した新規の糖尿病予防メカニズムの解明と臨床応用2013

    • Author(s)
      小塚 智沙代, 屋比久 浩市, 砂川 澄人, 平良 伸一郎, 植田 玲, 比嘉 盛丈, 池間 朋己, 山川 研, 高山 千利, 松下 正之, 親泊 政一, 島袋 充生, 益崎 裕章
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本市
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] 玄米由来成分γ-オリザノールによる膵島機能改善・抗肥満症効果の分子メカニズム2013

    • Author(s)
      小塚 智沙代, 屋比久 浩市, 砂川 澄人, 土井 基嗣, 中山 良朗, 平良 伸一郎, 植田 玲, 比嘉 盛丈, 池間 朋己, 山川 研, 高山 千利, 松下 正之, 親泊 政一, 島袋 充生, 益崎 裕章
    • Organizer
      第34回日本肥満学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] 動脈硬化を操る代謝シグナルネットワークの解明から治療へ 高尿酸血症と血管機能異常・動脈硬化2012

    • Author(s)
      益崎 裕章, 山川 研, 岩渕 敬子, 屋比久 浩市, 砂川 澄人, 小塚 智沙代, 植田 玲, 平良 伸一郎, 池間 朋己, 比嘉 盛丈, 島袋 充生
    • Organizer
      日本動脈硬化学会総会
    • Place of Presentation
      ヒルトン福岡シーホーク 福岡県福岡市
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] 医食同源 「食」のセンシングとメタボエイジング 日本屈指のメタボ県、沖縄から健康長寿復興を目指す食と新しい医療を考える2012

    • Author(s)
      益崎 裕章, 小塚 智沙代, 屋比久 浩市, 平良 伸一郎, 砂川 澄人, 植田 玲, 大城 譲, 池間 朋己, 山川 研, 比嘉 盛丈, 島袋 充生
    • Organizer
      日本抗加齢医学会
    • Place of Presentation
      パシフィコ横浜 神奈川県横浜市
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] 玄米成分γ-オリザノールは視床下部小胞体ストレス抑制を介して高脂肪食嗜好性を軽減する2012

    • Author(s)
      小塚 智沙代, 屋比久 浩市, 砂川 澄人, 植田 玲, 平良 伸一郎, 比嘉 盛丈, 池間 朋己, 山川 研, 高山 千利, 松下 正之, 親泊 政一, 島袋 充生, 益崎 裕章
    • Organizer
      日本肥満学会
    • Place of Presentation
      ホテルグランヴィア京都 京都府京都市
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] 玄米による新規抗肥満・抗糖尿病効果 視床下部小胞体ストレス抑制を介した高脂肪食嗜好性の軽減2012

    • Author(s)
      小塚 智沙代, 屋比久 浩市, 砂川 澄人, 平良 伸一郎, 植田 玲, 比嘉 盛丈, 池間 朋己, 山川 研, 高山 千利, 松下 正之, 親泊 政一, 島袋 充生, 益崎 裕章
    • Organizer
      日本内分泌学会
    • Place of Presentation
      北九州国際会議場 福岡県北九州市
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] Effects of miglitol on fat distribution and insulin sensitivity in subjects with metabolic syndrome., Kyoto, Japan2010

    • Author(s)
      Shimabukuro M
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      京都国際会議場(京都府)
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] 肥満糖尿病の病態:沖縄クライシスの現場からの考察2010

    • Author(s)
      益崎裕章, 島袋充生, 山川研, 屋比久浩市, 池間朋己, 比嘉盛丈
    • Organizer
      第48回日本糖尿病学会九州地方会シンポジウム1
    • Place of Presentation
      別府市
    • Year and Date
      2010-10-29
    • Data Source
      KAKENHI-PROJECT-20590542
  • [Presentation] Ectopic fat deposition(EFD), metabolic syndrome, and type 2 diabetes2010

    • Author(s)
      Shimabukuro M
    • Organizer
      ICE 2010 Satellite program, Obesity and Metabolic Syndrome
    • Place of Presentation
      京都国際会議場(京都府)
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] 若齢期に対する人工甘味料曝露給餌によるレプチン抵抗性獲得と高尿酸血症の誘導高尿酸血症2010

    • Author(s)
      屋比久浩市(代表者)、大城譲、砂川澄人、小塚智沙代、平良伸一郎、植田玲、仲本桂子、岩渕敬子、與那覇恵、山川研、比嘉盛丈、島袋充生、高山千利、益崎裕章
    • Organizer
      メタボリックシンドロームリサーチフォーラム第6回研究集会
    • Place of Presentation
      大阪府大阪市ホテルグランヴィア大阪
    • Year and Date
      2010-08-06
    • Data Source
      KAKENHI-PROJECT-22591014
  • [Presentation] Ectopic fat deposition (EFD), metabolic syndrome, and type 2 diabetes.2010

    • Author(s)
      Shimabukuro M, Masuzaki H.
    • Organizer
      ICE 2010 Satellite program, Obesity and Metabolic Syndrome.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] Ectopic fat deposition and lipotoxic disorders.2010

    • Author(s)
      Shimabukuro M, Masuzaki H.
    • Organizer
      JES-Sponsored Symposia, 14th International Congress of Endocrinology
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-03-28
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] Ectopic fat deposition and lipotoxic disorders2010

    • Author(s)
      Shimabukuro M
    • Organizer
      JES-Sponsored Symposia, 14th International Congress of Endocrinology
    • Place of Presentation
      京都国際会議場(京都府)
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] Visceral adiposity strongly predicts delayed hyperinsulinemia in obese and non-obese subjects2010

    • Author(s)
      Shimabukuro M
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      京都国際会議場(京都府)
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] 若齢期の人工甘味料曝露によるレプチン抵抗性獲得機構の解明2010

    • Author(s)
      屋比久浩市(代表者)、大城譲、砂川澄人、小塚智沙代、 幸喜毅、平良伸一郎、植田玲、仲本桂子、岩渕敬子、山川研、比嘉盛丈、島袋充生、高山千利、益崎裕章
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山県岡山市デジタルミュージアム
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-22591014
  • [Presentation] Effects of miglitol on fat distribution and insulin sensitivity in subjects with metabolic syndrome.2010

    • Author(s)
      Shimabukuro M, Higa M, Tanaka H, Uezu Y. Masuzaki H.
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] Visceral adiposity strongly predicts delayed hyperinsulinemia in obese and non-obese subjects.2010

    • Author(s)
      Shimabukuro M, Higa M, Masuzaki H.
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] Effects of brown and white rice diet on visceral adiposity and endothelial function : The BRAVO study.2010

    • Author(s)
      Hasegawa J, Higa M, Tanaka H, Shimabukuro M, Masuzaki H.
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] Effects of a single ingestion of brown and white rice on metabolic parameters and endothelial function.2008

    • Author(s)
      Higa M, Tanaka H, Shimabukuro M.
    • Organizer
      2nd International Symposium on Rice and Disease Prevention
    • Place of Presentation
      Wakayama Prefectural Culture Hall, Wakayama, Japan
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] Effects of abdominal obesity and insulin resistance on blood pressure and cardiovascular events : A prospective study in 6975 community-based subjects.2008

    • Author(s)
      Shimabukuro M, Higa M, Tanaka H, Shiohira Y, Miyahira M.
    • Organizer
      World Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension (CODHy)
    • Place of Presentation
      Catalonia Palace of Congresses, Barcelona, Spain
    • Year and Date
      2008-11-01
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] Visceral adiposity causes delayed hyperinsulinemia even in non-obese subjects.2008

    • Author(s)
      Higa M, Shimabukuro M, Shiohira Y.
    • Organizer
      World Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension (CODHy)
    • Place of Presentation
      Catalonia Palace of Congresses, Barcelona, Spain
    • Year and Date
      2008-11-01
    • Data Source
      KAKENHI-PROJECT-20590651
  • [Presentation] 玄米による食行動の改善を介した血管機能異常改善効果

    • Author(s)
      小塚 智沙代, 砂川 澄人, 比嘉 盛丈, 池間 朋己, 山川 研, 高山 千利, 松下 正之, 親泊 政一, 島袋 充生, 益崎 裕章
    • Organizer
      第18回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      横浜市開港記念会館
    • Year and Date
      2014-11-21 – 2014-11-22
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] 玄米有効成分による膵β細胞保護効果の新規メカニズム

    • Author(s)
      小塚 智沙代, 砂川 澄人, 中山 良朗, 土井 基嗣, 平良 伸一郎, 植田 玲, 比嘉 盛丈, 池間 朋己, 山川 研, 高山 千利, 松下 正之, 親泊 政一, 島袋 充生, 益崎 裕章
    • Organizer
      第87回日本内分泌学会学術総会
    • Place of Presentation
      福岡国際会議場・福岡サンパレス
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-24591063
  • [Presentation] メタボリックストレスモデルにおけるキサンチンオキシダーゼ阻害薬の血管内皮機能改善効果について

    • Author(s)
      砂川 澄人, 山川 研, 岩渕 敬子, 小塚 智沙代, 白倉 尚, 田村 みずほ, 仲村 英昭, 土井 基嗣, 中山 良朗, 植田 玲, 新垣 多賀子, 平良 伸一郎, 池間 朋己, 友寄 毅昭, 島尻 佳典, 大城 譲, 比嘉 盛丈, 島袋 充生, 益崎 裕章
    • Organizer
      第87回日本内分泌学会学術総会
    • Place of Presentation
      福岡国際会議場・福岡サンパレス
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-24591063
  • 1.  MASUZAKI Hiroaki (00291899)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 33 results
  • 2.  KOUKI Tsuyoshi (80273415)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  YAMAKAWA Ken (00363664)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 18 results
  • 4.  UEDA Shinichiro (80285105)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YABIKU Kouichi (70545748)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 6.  TAKAYAMA Chitoshi (60197217)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 7.  KOMIYA Ichiro (50162061)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  旭 浩一 (60274966)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 9.  YASU Takanori (40265278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KARIYA Kenichi (40263371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HIGA Moritake (70347152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 12.  YOSHIDA Hisashi (50210711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KUWAJIMA Masamichi (00205262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MIZUNO Akira (80219641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NOMA Yoshihiko (10218349)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  DOI Toshio (60183498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ISHIMURA Kazunori (90112185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKISHITA Syuichi (90108712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YASUNARI Kenichi (90231646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TAKASU Nobuyuki (20020927)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  OHTA Takao (70185271)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 22.  SAKU Keijiro (40183371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  AWATA Hisataka (00325862)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  YOSHIDA Tomohide (20363682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  SHIMABURURO Tadao (20336382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  KUDO AKIHIRO (20528096)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  Ogata Emi (80627307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 28.  小田 高也 (10332909)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  村上 尚 (40210009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  梅村 敏 (00128589)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  砂川 信 (60332904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  MATUSHITA Masayuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  KOZUKA Chisayo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 34.  AIHARA Ken-ihchi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  IWASE Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  KUROBE Hirotsugu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 37.  OYADOMARI Seiichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  佐田 政隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 39.  福田 大受
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 40.  田中 君枝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  金山 朱里
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 42.  平田 恭信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 43.  添木 武
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 44.  高浜 洋介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  近藤 正英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  親泊 美帆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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