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Awaji Takeo  淡路 健雄

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AWAJI Takeo  淡路 健雄

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Researcher Number 60297546
Other IDs
Affiliation (Current) 2025: 埼玉医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2021: 埼玉医科大学, 医学部, 准教授
2014 – 2016: 埼玉医科大学, 医学部, 准教授
2011 – 2013: 埼玉医科大学, 医学部, 講師
2007 – 2009: Saitama Medical University, 医学部, 講師
2002 – 2007: TWMU, Department of Physiology, Lecturer, 医学部, 講師
1997 – 2002: Tokyo Women's Medical College, School of Medicine, Researchi assistant, 医学部, 助手
1998: 東京女子医科大学, 医学部
Review Section/Research Field
Principal Investigator
Basic Section 56030:Urology-related / General physiology / General pharmacology / General pharmacology / General physiology
Except Principal Investigator
General physiology / Biological pharmacy / Metabolomics / General physiology / Metabolomics / General pharmacology
Keywords
Principal Investigator
GPR120 / 不飽和脂肪酸受容体 / green fluorescent protein / 抗体 / 三量体G蛋白共役型受容体 / 三量体Gタンパク質共役型受容体 / 多価不飽和脂肪酸 / 不飽和脂肪酸 / αリノレン酸 / 精子 … More / 長鎖不飽和脂肪酸受容体 / 長鎖不飽和脂肪酸 / Hydrion density / subcellular localization / Ca^<2+> oscillations / α_1-adrenoceptor / α1受容体 / 細胞内局在 / GFP / α_1受容体 / pH可視化測定 / GPR40 / 細胞内カルシウム濃度 / 可視化解析 / GPR 40 / 三量体共役形受容体 / 細胞内シグナル伝達機構 / ミトコンドリア機能 / 水素イオン濃度 / 細胞内カルシウムイオン濃度測定 / 生命現象可視化 / Green Fluorescent Protein / 細胞内移行 / アドレナリン受容体 / 可視化測定 / 水素イオン / 細胞内微小環境 / 情報伝達機構 / GFP(Green Fluorescent Protein) / α_<1b>受容体 / adrenoceptor / internalization / Green fluorescent protein … More
Except Principal Investigator
MODY / 受精 / カルシウムオシレーション / 哺乳動物卵 / 細胞内カルシウムイオン / 精子因子 / 卵活性化 / HNF4α / 卵活性化蛋白質 / 核移行 / ホスフォリパーゼCゼータ / Fertilization / 精子細胞質因子 / 脂肪酸受容体 / GPR120 / ミトコンドリア / genome / pharmaceutical sciences / Microarray / signal transduction / Proteome / 質量分析 / ペプチド / 分泌 / 脂肪酸 / オーファン受容体 / ゲノム / 薬学 / マイクロアレイ / シグナル伝達 / プロテオーム / Nuclear transpotation abity / Phospholipase C-zeta / Egg-activating Protein / Cytosolic Sperm Factor / Calcium Oscillation / Mammalian Eggs / Intracellular Calcium Ion / 核移行能 / ホスホリパーゼCゼータ / Ca^<2+> oscillations / green fluorescent protein / insulin secreting cell / ミトコンドリア機能 / 細胞内局在 / PH可視化測定 / β細胞 / GFP / pH可視化測定 / Diabetes Mellitus / SHP / HNF4 α / 転写因子 / 糖尿病 / nuclear translocation / phospholipase C zeta / sperm factor / calcium oscillation / intracellular calcium ion / egg activation / mammalian egg / fertilization / 卵細胞内精子注入法(ICSI) / CD9 / 精子一卵融合 / 前核 / Calpain 10 / Mitochondrial gene / mutation / hepatocyte nuclear factor / gene / type 2 diabetes / genome-wide scan / HNF-1β / MODY4 / 1PF-1 / NKX2,2 / NEUROD1 / BETA2 / NIDDM / 罹患同胞対法 / β3 adrenergic receptor / 妊婦糖尿病 / 体重増加 / HNF1β / MODY5 / 疾患感受性遺伝子座位 / 羅患同胞対法 / カルパイン10 / NIDDM1 / 発症遺伝子 / 疾患感受性座位 / 日本人2型糖尿病 / 全ゲノムスギャン / ESRD / ミトコンドリア遺伝子 / 多因子疾患 / 罹患同胞対(法) / HNF / 遺伝子 / 2型糖尿病 / Sperm Factor / Egg Activation / Ca^<2+> Oscillation / Intracellular Ca^<2+> / Mammalian Egg / 精子蛋白質 / Ca^<2+>オシレーション / 細胞内Ca^<2+>イオン / Ca^<2+> OSCILLATION / Ca^<2+> WAVE / INTRACELLUAR Ca^<2+> / EGG ACTIVATION / SPERM / EGG / FERTILIZATION / 細胞内カルシウム / 卵活性化因子 / 哺乳動物精子 / カルシウム振動 / カルシウム波 / 精子 / 卵子 / 天然由来成分 / 生活習慣病 / 野生型マウス / 天然化合物 / タウ / タウタンパク質 / アミロイドβタンパク質 / アルツハイマー病 / ドッキングシミュレーション / シミュレーション / 肥満 / 蛍光プローブ / GPR40 / 分子生物学脂肪酸受容体 / ゲノム創薬科学 / フローサイトメーター / GPCR / 薬理学 / Green Fluorescent Protein / Green fluorescent Protein / 可視化解析 / 遺伝子発現 / 哺乳類卵細胞 Less
  • Research Projects

    (17 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (22 People)
  •  Analysis of sperm function mediated by polyunsaturated fatty acid receptor GPR120Principal Investigator

    • Principal Investigator
      Awaji Takeo
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Saitama Medical University
  •  Readjustment of "amyloid hypothesis" for developing methods to treat Alzheimer disease

    • Principal Investigator
      Maruyama Kei
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Saitama Medical University
  •  Elucidation of physiological role of the fatty acid receptor bycomputer simulation and the fluorescent probe detection system

    • Principal Investigator
      HIRASAWA Akira
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Physiological role of free fatty acid receptor GPR120.

    • Principal Investigator
      HIRASAWA Akira
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Long chain fatty acid receptor function using visualization of mitochondrial functionPrincipal Investigator

    • Principal Investigator
      AWAJI Takeo
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Saitama Medical University
  •  Regulation of peptides secretion by orphan G protein coupled receptor

    • Principal Investigator
      HIRASAWA Akira
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Characterization and functional analysis of phospholipase C-zeta, a candidate of mammalian egg-activating sperm factor

    • Principal Investigator
      MIYAZAKI Shunichi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Tokyo Women's Medical University
  •  Relationship between subcellular localization of α-adrenoceptor subtypes and function on ischemiaPrincipal Investigator

    • Principal Investigator
      AWAJI Takeo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Tokyo Women's Medical University
  •  Mithochondrial pH in virtal inslinoma cell line INS-1 with glucose stimulant Ca release

    • Principal Investigator
      OGATA Makiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Tokyo Women's Medical University
  •  pHプローブ融合アドレナリンα_1受容体作成による受容体調節機構の解析Principal Investigator

    • Principal Investigator
      淡路 健雄
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Tokyo Women's Medical University
  •  哺乳類卵子での遺伝子発現系の開発と応用

    • Principal Investigator
      MIYAZAKI Shunichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General physiology
    • Research Institution
      Tokyo Women's Medical University
  •  Identification of sperm-derived egg-activating protein at fertilization of mammalian eggs

    • Principal Investigator
      MIYAZAKI Shunichi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Tokyo Women's Medical University
  •  Study for onset of MODY, by gene mutation of transcriptional factor, using cellular localization

    • Principal Investigator
      OGATA Makiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Tokyo Women's Medical University
  •  Identification of Ca^<2+>-oscillation-inducing Protein and Analysis of Its Action

    • Principal Investigator
      MIYAZAKI Shunichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General physiology
    • Research Institution
      Tokyo Women's Medical University
  •  新規蛋白相互作用可視化技術によるG蛋白質共役型受容体調節機構の時空間的解析Principal Investigator

    • Principal Investigator
      淡路 健雄
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General physiology
    • Research Institution
      Tokyo Women's Medical University
  •  Searching for the responsible genes for developing type 2 diabetes mellitus in Japanese

    • Principal Investigator
      NAOKO Iwasaki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Tokyo Women's Medical University
  •  Identification of sperm-derived egg-activating factor and analysis of molecular mechanisms of intracellular Ca^<2+> increase at fertilization of mammalian eggs

    • Principal Investigator
      MIYAZAKI Shunichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Tokyo Women's Medical College

All 2021 2017 2016 2015 2014 2013 2009 2008 2006 2005 2004 Other

All Journal Article Presentation Patent

  • [Journal Article] A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus2021

    • Author(s)
      Iwasa Kensuke、Yamamoto Shinji、Yamashina Kota、Yagishita-kyo Nan、Maruyama Kei、Awaji Takeo、Takei Yoshinori、Hirasawa Akira、Yoshikawa Keisuke
    • Journal Title

      Journal of Neuroinflammation

      Volume: 18 Issue: 1 Pages: 304-304

    • DOI

      10.1186/s12974-021-02361-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09148, KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-21K06807, KAKENHI-PROJECT-18K17933
  • [Journal Article] Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging.2017

    • Author(s)
      Yagishita S, Suzuki S, Yoshikawa K, Iida K, Hirata A, Suzuki M, Takashima A, Maruyama K, Hirasawa A, Awaji T.
    • Journal Title

      Mol Brain

      Volume: 10 Issue: 1 Pages: 2-2

    • DOI

      10.1186/s13041-016-0282-7

    • NAID

      120005971848

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460341, KAKENHI-PROJECT-25870677, KAKENHI-PROJECT-16K15777, KAKENHI-PROJECT-16K21328, KAKENHI-PLANNED-26117004
  • [Journal Article] Prostaglandin F2α FP receptor inhibitor reduces demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model2014

    • Author(s)
      Iwasa K, Yamamoto S, Takahashi M, Suzuki S, Yagishita S, Awaji T, Maruyama K, Yoshikawa K
    • Journal Title

      Prostaglandins, Leukotrienes and Essential Fatty Acids

      Volume: 91 Issue: 5 Pages: 175-182

    • DOI

      10.1016/j.plefa.2014.08.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460341, KAKENHI-PROJECT-25670781, KAKENHI-PROJECT-25870677, KAKENHI-PROJECT-26670126
  • [Journal Article] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction in mice2014

    • Author(s)
      Yamamoto S, Gotoh M, Kawamura Y, Yamashina K, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K.
    • Journal Title

      European Journal of Pharmacology

      Volume: 741 Pages: 17-24

    • DOI

      10.1016/j.ejphar.2014.07.040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460341, KAKENHI-PROJECT-25670781, KAKENHI-PROJECT-25870677, KAKENHI-PROJECT-26860144
  • [Journal Article] FFA1-selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models2013

    • Author(s)
      Takeuchi M, Hirasawa A, Hara T, Kimura I, Hirano T, Suzuki T, Miyata N, Awaji T, Ishiguro M, Tsujimoto G
    • Journal Title

      Br J Pharmacol

      Volume: 168 Pages: 1570-1583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Flow cytometry-based binding assay for GPR40(FFAR1; free fatty acid receptor 1).2009

    • Author(s)
      Hara T, Hirasawa A, Sun Q, Koshimizu TA, Itsubo C, Sadakane K, Awaji T, Tsujimoto G.
    • Journal Title

      Molecular Pharmacology 75(1)

      Pages: 85-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590260
  • [Journal Article] The role of X/Y linker region and N-terminal EF-hand domain in nuclear translocation and Ca^<2+> oscillation-inducing activities of phospholipase C a mammalian egg-activating factor2006

    • Author(s)
      Kuroda, K., Ito, M., Shikano, T., Awaji, T., Yoda, A., Takeuchi, H., Kinoshita, K., Miyazaki, S.
    • Journal Title

      Journal of Biological Chemistry 281

      Pages: 27794-27805

    • Data Source
      KAKENHI-PROJECT-16390055
  • [Journal Article] The role of X/Y linker region and N-terminal EF-hand domain in nuclear translocation and Ca^<2+> oscillation-inducing activities of phospholipase Cζ, a mammalian egg-activating factor2006

    • Author(s)
      Kuroda, K., Ito, M., Shikano, T., Awaji, T., Yoda, A., Takeuchi, H., Kinoshita, K., Miyazaki.S.
    • Journal Title

      Journal of Biological Chemistry 281

      Pages: 27794-27805

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390055
  • [Journal Article] The role of X/Y linker region and N-terminal EF-hand domain in nuclear translocation and Ca^<2+> oscillation-inducing activities of phospholipase Cζ, a mammalian egg-activating factor2006

    • Author(s)
      Kuroda K, Ito M, Shikano T, Awaji T, Yoda A, Takeuchi H, Kinoshita K, Miyazaki S
    • Journal Title

      Journal of Biological Chemistry 281

      Pages: 27794-27805

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390055
  • [Journal Article] Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR1202005

    • Author(s)
      Hirasawa, A., Awaji, T.et al.
    • Journal Title

      Nat Med 11

      Pages: 90-94

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590192
  • [Journal Article] Ca2+ oscillation-inducing phospholipase C zeta expressed in mouse eggs is accumulated to the pronucleus during egg activation2005

    • Author(s)
      Yoda, A., Awaji, T.
    • Journal Title

      Dev Biol 268

      Pages: 245-257

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590957
  • [Journal Article] Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR1202005

    • Author(s)
      Hirasawa, A., Awaji, T.et al.
    • Journal Title

      Nat Med 11

      Pages: 90-94

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590957
  • [Journal Article] Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR 120.2005

    • Author(s)
      Hirasawa, A., K.Tsumaya, T.Awaji, S.Katsuma, T.Adachi, M.Yamada, Y.Sugimoto, S.Miyazaki, G.Tsujimoto
    • Journal Title

      Nat Med. 11

      Pages: 90-94

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590192
  • [Journal Article] Ca2+ oscillation-inducing phospholipase C zeta expressed in mouse eggs is accumulated to the pronucleus during egg activation2005

    • Author(s)
      Yoda, A., Awaji, T.
    • Journal Title

      Dev Biol 268

      Pages: 245-257

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590192
  • [Journal Article] Ca^<2+> oscillation-inducing phospholipase C zeta expressed in mouse eggs is accumulated to the pronucleus during egg activation2004

    • Author(s)
      Yoda A, Oda S, Shikano T, Kouchi Z, Awaji T, Shirakawa H, Kinoshita K, Miyazaki S
    • Journal Title

      Developmental Biology 268

      Pages: 245-257

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390055
  • [Journal Article] Ca^<2+> oscillation-inducing phospholipase C zeta expressed in mouse eggs is accumulated to the pronucleus during egg activation2004

    • Author(s)
      Yoda A, Oda S, Shikano T, Kouchi Z, Awaji T, Shirakawa H, Kinoshita K, Miyazaki S.
    • Journal Title

      Developmental Biology 268

      Pages: 245-257

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390055
  • [Journal Article] Ca^<2+> oscillation-inducing phospholipase C zeta expressed in mouse eggs is accumulated to the pronucleus during egg activation.2004

    • Author(s)
      Yoda, A., S.Oda, T.Shikano, Z.Kouchi, T.Awaji, H.Shirakawa, K.Kinoshita, S.Miyazaki
    • Journal Title

      Dev Biol. 268

      Pages: 245-257

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590192
  • [Patent] タウタンパク質のリン酸化が亢進された非ヒトモデル動物の製造方法2013

    • Inventor(s)
      栁下聡介,鈴木正彦,淡路健雄,吉川圭介,丸山敬,鈴木星也
    • Industrial Property Rights Holder
      学校法人埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-130358
    • Filing Date
      2013-06-21
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] 内在性タウのリン酸化亢進モデルマウスのマイクロアレイ解析2016

    • Author(s)
      柳下聡介,淡路健雄,鈴木星也,飯田桂子,平田理子,鈴木正彦,丸山敬,平澤明
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-03-10
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] 内在性リン酸化タウ増加モデルのマイクロアレイ解析2016

    • Author(s)
      栁下聡介,鈴木星也,吉川圭介,飯田桂子,平田理子,鈴木正彦,高島明彦,丸山敬,平澤明,淡路健雄
    • Organizer
      第35回 日本認知症学会
    • Place of Presentation
      東京
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction2015

    • Author(s)
      Yamamoto S, Gotoh M, Kawamura Y, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K
    • Organizer
      ECTRIMS (European committee for treatment and research in Multiple Sclerosis)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2015-10-07
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] プロスタグランジンF2α FPレセプター阻害は多発性硬化症モデルマウスの神経脱髄と運動障害を改善する2015

    • Author(s)
      岩佐健介、山本梓司、高橋茉莉香、鈴木星也、柳下聡介、淡路健雄、丸山敬、吉川圭介
    • Organizer
      第57回日本脂質生化学会
    • Place of Presentation
      東京都(一橋大学)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] Prostaglandin F2α FP receptor inhibitor reduces demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model2015

    • Author(s)
      岩佐健介、山本梓司、高橋茉莉香、鈴木星也、柳下聡介、淡路健雄、丸山敬、吉川圭介
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-03-20
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] 内在性タウのリン酸化亢進モデルマウスはアルツハイマー病様の表現型を呈する2015

    • Author(s)
      柳下聡介,鈴木星也,鈴木正彦,丸山敬,平澤明,淡路健雄
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-03-20
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] リン酸化タウが増加する新規モデルマウスの作製及びその解析2014

    • Author(s)
      栁下聡介,鈴木星也,淡路健雄,平澤明,鈴木正彦,丸山敬
    • Organizer
      日本薬理学会関東部会(第131回)
    • Place of Presentation
      横浜市立大学福浦キャンパス(横浜市金沢区)
    • Year and Date
      2014-10-11
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] Establishment of a new mouse model with accelerated phosphorylation of endogenous tau2014

    • Author(s)
      Seiya Suzuki, Sosuke Yagishita, Ayaka Sorimachi, Maya Moriizumi, Takeo Awaji, Masahiko Suzuki, Kei Maruyama
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      宮城県 仙台市
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] 間歇的低酸素負荷による内在性タウのリン酸化亢進モデルマウスの作製2013

    • Author(s)
      鈴木星也,柳下聡介,淡路健雄,鈴木正彦,丸山敬
    • Organizer
      第129回 日本薬理学会関東部会
    • Place of Presentation
      順天堂大学(本郷キャンパス)
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] 野生型マウスを用いた内在性タウのリン酸化亢進モデルマウスの作製2013

    • Author(s)
      鈴木星也,柳下聡介,淡路健雄,鈴木正彦,丸山敬
    • Organizer
      日本認知症学会
    • Place of Presentation
      長野県 松本市
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] 内在性タウのリン酸化亢進マウスモデルの作製2013

    • Author(s)
      鈴木星也,柳下聡介,淡路健雄,鈴木正彦,丸山敬
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] A new system to determine the Mitochondrial pH in cultured living β-cell2009

    • Author(s)
      Makiko Ogata, Takeo Awaji, Naoko Iwasaki, Risa Fujimaki, Miho Takizawa, Yasuhiko Iwamoto, Kei Maruyama
    • Organizer
      第82回日本薬理学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-17
    • Data Source
      KAKENHI-PROJECT-19590260
  • [Presentation] 培養膵β生細胞を用いたミトコンドリア機能の経時的定量評価の検討2008

    • Author(s)
      尾形真規子, 淡路健雄, 岩崎直子, 藤巻理沙, 滝沢美保, 丸山敬, 岩本安彦
    • Organizer
      第51回日本糖尿病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19590260
  • [Presentation] A new system to determine the Mitochondrial pH in cultured living・・cell2008

    • Author(s)
      Makiko Ogata, Naoko Iwasaki, Takeo Awaji, Risa Fujimaki, Miho Takizawa, Kei Maruyama, Yasuhiko Iwamoto
    • Organizer
      第8回日本ミトコンドリア学会年会
    • Place of Presentation
      東京
    • Year and Date
      2008-12-18
    • Data Source
      KAKENHI-PROJECT-19590260
  • [Presentation] Establishment of a non-transgenic mouse model of neurodegenerative diseases with accelerated phosphorylation of endogenous tau

    • Author(s)
      Sosuke Yagishita, Seiya Suzuki, Takeo Awaji, Keisuke Yoshikawa, Masahiko Suzuki, Akira Hirasawa, Kei Maruyama
    • Organizer
      第12回 RCGM フロンティア国際シンポジウム
    • Place of Presentation
      埼玉医科大学日高キャンパス(埼玉県日高市)
    • Year and Date
      2014-10-31 – 2014-11-01
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction

    • Author(s)
      Yamamoto S, Gotoh M, Kawamura Y, Yamashina K, Yagishita S, Awaji T, Tanaka M, Maruyama K, Murakami-Murofushi K, Yoshikawa K
    • Organizer
      PLM2015 (Phospholipase and other lipid mediators)
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-02-10 – 2015-02-12
    • Data Source
      KAKENHI-PROJECT-25460341
  • [Presentation] Prostaglandin F2α FP receptor inhibitor reduce demyelination and motor dysfunction in a cuprizone-induced multiple sclerosis mouse model

    • Author(s)
      Iwasa K, Yamamoto S, Takahashi M, Suzuki S, Yagishita S, Awaji T, Maruyama K, Yoshikawa K
    • Organizer
      PLM2015 (Phospholipase and other lipid mediators)
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-02-10 – 2015-02-12
    • Data Source
      KAKENHI-PROJECT-25460341
  • 1.  HIRASAWA Akira (70242633)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 2.  MIYAZAKI Shunichi (80010081)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 3.  KOHCHI Zen (70322485)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 4.  OGATA Makiko (10233404)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  ODA Shoji (50266714)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 6.  NAOKO Iwasaki (70203370)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  LIU Ning (70464196)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  IIDA Keiko (00422999)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SHIRAKAWA Hideki (40241070)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 10.  KOSHIMIZU Taka-aki (20392491)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Maruyama Kei (30211577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 12.  Kondo Ryuichiro (80091370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Kuniyoshi Shimizu (20346836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SHIRAISHI Koichi (50256476)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MOHRI Tatsuma (60290912)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ITO Masahiko (50385423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 17.  HAYANO Toshiya (90332303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  吉川 圭介 (10435860)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 19.  柳下 聡介 (30585592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 20.  田丸 文信 (70337541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  梶原 健 (80286103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  河村 真規子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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