Saito Hiroyuki 斎藤博幸

… Alternative Names

斎藤博幸サイトウヒロユキ

SAITO Hiroyuki 斎藤博幸

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Researcher Number	60300919
External Links
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 京都薬科大学, 薬学部, 教授 2022 – 2023: 京都薬科大学, 薬学部, 教授 2015 – 2020: 京都薬科大学, 薬学部, 教授 2012 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 教授 2010 – 2012: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 … More 2007 – 2008: Kobe Pharmaceutical University, 薬学部, 教授 2004: 医薬品食品衛生研, 研究員 1998 – 2003: 国立医薬品食品衛生研究所, 大阪支所・薬品試験部, 研究員 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Functional materials/Devices
Keywords	Principal Investigator 脂質膜 / アミロイドーシス / アポリポタンパク質 / 抗体 / 薬学 / 生物物理化学 / 蛋白質 / ABCトランスポーター / アミロイド / HDL … More / アミロイド線維 / 脂質異常症 / リポタンパク質 / ペプチド / アポA-I / NMR / 蛍光プローブ / コレステロール / エマルション / タンパク質 / 構造特異抗体 / 遺伝子変異 / 重金属結合タンパク質 / 安定化人工脂質 / 高密度リポタンパク質 / 膜タンパク質 / 再構成 / 脂質膜ディスク / コレステロール代謝 / ＨＤＬ / 糖鎖 / コンフォメーション / 部位特異的蛍光標識 / 脂質結合構造 / フォールディング構造 / フォールディング構造異常 / グリコサミノグリカン / アルツハイマー病 / 脂質代謝異常 / 超高感度マイクロカロリメータ / 国際研究者交流(米国) / ヘパラン硫酸プロテオグリカン / ヘパリン / 表面プラズモン共鳴(SPR) / 遺伝分子多型 / アポリポタンパク質E / リボソーム / アポリポタンパク質A-I / 超高感度熱量測定 / 励起エネルギー移動 / 蛍光異方性 / アポE / リポ蛋白質 / 血中滞留性 / スフィンゴミエリン / アポリポ蛋白質 / リポ蛋白質リパーゼ … More Except Principal Investigator バイオセンサ / 蛋白質 / 脂質 / 超薄膜 / 生物物理 / 生体機能応用デバイス Less

タンパク質の自己凝集・アミロイド線維化を促進する体内分子ネットワークの解明と制御Principal Investigator
- Principal Investigator
  
  斎藤博幸
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto Pharmaceutical University
Mechanisms of aggregation and fibril formation of amyloidogenic proteins with amyloid cofactorsPrincipal Investigator
- Principal Investigator
  
  斎藤博幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto Pharmaceutical University
Physicochemical mechanisms of amyloid fibril formation by amyloidogenic apolipoproteinsPrincipal Investigator
- Principal Investigator
  
  Saito Hiroyuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Physicochemical mechanism on formation and metabolism of HDL particles by apolipoproteinsPrincipal Investigator
- Principal Investigator
  
  Saito Hiroyuki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
  The University of Tokushima
Development of HDL-like lipid membrane discs for reconstitution of membrane proteinsPrincipal Investigator
- Principal Investigator
  
  SAITO Hiroyuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Basic research on handling of heavy-metal ion transporter protein as a sensor element
- Principal Investigator
  
  BABA Teruhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional materials/Devices
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Structural basis of dysfunctional apolipoprotein-induced dyslipidemiaPrincipal Investigator
- Principal Investigator
  
  SAITO Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Role of Apolipoprotein E Structure in Disorders of Lipid Metabolism in BrainPrincipal Investigator
- Principal Investigator
  
  SAITO Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kobe Pharmaceutical University
アポリポタンパク質Eの脂質及び細胞受容体結合の分子機構Principal Investigator
- Principal Investigator
  
  斎藤博幸
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Health Sciences
モデルペプチドを用いたアポリポタンパク質脂質膜結合機構に関する研究Principal Investigator
- Principal Investigator
  
  斎藤博幸
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Health Sciences
血漿アポリポ蛋白質の結合選択性を利用した脂質エマルションの体内代謝の制御Principal Investigator
- Principal Investigator
  
  斎藤博幸
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Health Sciences

[Book] Lipids in Protein Misfolding2015
- Author(s)
  Gorbenko, G., Trusova, V., Girych, M., Adachi, E., Mizuguchi, C., and Saito, H.
- Total Pages
  260
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25293006
[Book] 製剤への物理化学第2版2012
- Author(s)
  斎藤博幸、田中秀治編
- Total Pages
  302
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-22590046
[Book] 製剤への物理化学第2版2012
- Author(s)
  斎藤博幸,他
- Total Pages
  302
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Generation of novel anti‐apo<scp>E</scp> monoclonal antibodies that selectively recognize apo<scp>E</scp> isoforms2024
- Author(s)
  Ohgita Takashi、Sakai Koto、Fukui Nodoka、Namba Norihiro、Nakano Miyu、Kiguchi Yuki、Morita Izumi、Oyama Hiroyuki、Yamaki Kouya、Nagao Kohjiro、Kobayashi Norihiro、Saito Hiroyuki
- Journal Title
  
  FEBS Letters
  
  Volume: in press. Issue: 8 Pages: 902-914
- DOI
  10.1002/1873-3468.14858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-21K15245
[Journal Article] Host-to-graft propagation of inoculated α-synuclein into transplanted human induced pluripotent stem cell-derived midbrain dopaminergic neurons2024
- Author(s)
  Gima Serina、Oe Kazuya、Nishimura Kaneyasu、Ohgita Takashi、Ito Haruka、Kimura Hiroyuki、Saito Hiroyuki、Takata Kazuyuki
- Journal Title
  
  Regenerative Therapy
  
  Volume: 25 Pages: 229-237
- DOI
  10.1016/j.reth.2023.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-21K15245, KAKENHI-PROJECT-20H03569
[Journal Article] Intramolecular interaction kinetically regulates fibril formation by human and mouse α-synuclein2023
- Author(s)
  Ohgita Takashi、Kono Hiroki、Morita Izumi、Oyama Hiroyuki、Shimanouchi Toshinori、Kobayashi Norihiro、Saito Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 10885-10885
- DOI
  10.1038/s41598-023-38070-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-21K15245
[Journal Article] Amyloidogenic 60?71 deletion/ValThr insertion mutation of apolipoprotein A-I generates a new aggregation-prone segment that promotes nucleation through entropic effects2023
- Author(s)
  Namba Norihiro、Ohgita Takashi、Tamagaki-Asahina Hiroko、Nishitsuji Kazuchika、Shimanouchi Toshinori、Sato Takeshi、Saito Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 18514-18514
- DOI
  10.1038/s41598-023-45803-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-21K15245
[Journal Article] Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability2023
- Author(s)
  Takechi-Haraya Yuki、Ohgita Takashi、Usui Akiko、Nishitsuji Kazuchika、Uchimura Kenji、Abe Yasuhiro、Kawano Ryuji、Konaklieva Monika I.、Reimund Mart、Remaley Alan T.、Sato Yoji、Izutsu Ken-ichi、Saito Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 19396-19396
- DOI
  10.1038/s41598-023-46754-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-23K06092, KAKENHI-PROJECT-21K15245
[Journal Article] Plantainoside B in <i>Bacopa monniera</i> Binds to Aβ Aggregates Attenuating Neuronal Damage and Memory Deficits Induced by Aβ2023
- Author(s)
  Fukuda Aina、Nakashima Souichi、Oda Yoshimi、Nishimura Kaneyasu、Kawashima Hidekazu、Kimura Hiroyuki、Ohgita Takashi、Kawashita Eri、Ishihara Keiichi、Hanaki Aoi、Okazaki Mizuki、Matsuda Erika、Tanaka Yui、Nakamura Seikou、Matsumoto Takahiro、Akiba Satoshi、Saito Hiroyuki、Matsuda Hisashi、Takata Kazuyuki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 2 Pages: 320-333
- DOI
  10.1248/bpb.b22-00797
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06637, KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-22K07382, KAKENHI-PROJECT-21K15245, KAKENHI-PROJECT-20H03569
[Journal Article] Design and Synthesis of 6-O-Phosphorylated Heparan Sulfate Oligosaccharides to Inhibit Amyloid β Aggregation.2022
- Author(s)
  Uchimura K., Nishitsuji K, Chiu L.-T., Ohgita T., Saito H., Allain F., Gannedi V., Wong C.-H., and Hung S.-C.
- Journal Title
  
  ChemBioChem
  
  Volume: 23 Issue: 15 Pages: 4543-4543
- DOI
  10.1002/cbic.202200191
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-21K15245, KAKENHI-PROJECT-20K09605
[Journal Article] Mechanisms of enhanced aggregation and fibril formation of Parkinson’s disease-related variants of α-synuclein.2022
- Author(s)
  Ohgita T., Namba N., Kono H., Shimanouchi T., and Saito H.
- Journal Title
  
  Sci. Rep.
  
  Volume: 12 Issue: 1 Pages: 6770-6770
- DOI
  10.1038/s41598-022-10789-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-21K15245
[Journal Article] Analysis of the interaction of cyclosporine congeners with cell membrane models2022
- Author(s)
  Nakao Mizuka、Takechi-Haraya Yuki、Ohgita Takashi、Saito Hiroyuki、Demizu Yosuke、Izutsu Ken-Ichi、Sakai-Kato Kumiko
- Journal Title
  
  Journal of Pharmaceutical and Biomedical Analysis
  
  Volume: 218 Pages: 114874-114874
- DOI
  10.1016/j.jpba.2022.114874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05320, KAKENHI-PROJECT-22K06556
[Journal Article] Mechanisms of Aggregation and Amyloid Fibril Formation of Apolipoproteins on Lipid Membranes2021
- Author(s)
  Mizuguchi Chiharu、Ohgita Takashi、Saito Hiroyuki
- Journal Title
  
  MEMBRANE
  
  Volume: 46 Issue: 1 Pages: 25-31
- DOI
  10.5360/membrane.46.25
- NAID
  130007977581
- ISSN
  0385-1036, 1884-6440
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-21K15245
[Journal Article] Novel conformation‐selective monoclonal antibodies against apoA‐I amyloid fibrils2021
- Author(s)
  Takashi Ohgita, Yuki Furutani, Miyu Nakano, Megumi Hattori, Ayane Suzuki, Miho Nakagawa, Sera Naniwa, Izumi Morita, Hiroyuki Oyama, Kazuchika Nishitsuji, Norihiro Kobayashi, Hiroyuki Saito
- Journal Title
  
  FEBS Journal
  
  Volume: 288 Issue: 5 Pages: 1496-1513
- DOI
  10.1111/febs.15487
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-21K15245
[Journal Article] Phosphatidylethanolamine accelerates aggregation of the amyloidogenic N-terminal fragment of apoA-I.2020
- Author(s)
  Kurimitsu N., Mizuguchi C., Fujita K., Taguchi S., Ohgita T., Nishitsuji K., Shimanouchi T., and Saito H.
- Journal Title
  
  FEBS Lett.
  
  Volume: - Issue: 9 Pages: 1443-1452
- DOI
  10.1002/1873-3468.13737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03979
[Journal Article] Enhancement of direct membrane penetration of arginine-rich peptides by polyproline II helix structure2020
- Author(s)
  Takashi Ohgita, YukiTakechi-Haraya, KeisukeOkada, Saki Matsui, Misaki Takeuchi, Chihiro Saito, Kazuchika Nishitsuji, Kenji Uchimura, Ryuji Kawano, Koki Hasegawa, Kumiko Sakai-Kato, Kenichi Akaji, Ken-ichi Izutsu, Hiroyuki Saito
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1862 Issue: 10 Pages: 1-11
- DOI
  10.1016/j.bbamem.2020.183403
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-17H03979
[Journal Article] Nanomechanical Characterization of Apolipoprotein A-I Amyloid Fibrils2020
- Author(s)
  Trusova V., Vus K., Zhytniakivska O, Tarabara U., Saito H., and Gorbenko G.
- Journal Title
  
  East Eur. J. Phys.
  
  Volume: 2 Issue: 2 Pages: 118-123
- DOI
  10.26565/2312-4334-2020-2-11
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03979
[Journal Article] Sulfated glycosaminoglycans mediate prion-like behavior of p53 aggregates2020
- Author(s)
  Naoyuki Iwahashi, Midori Ikezaki, Taro Nishikawa, Norihiro Namba, Takashi Ohgita, Hiroyuki Saito, Yoshito Ihara, Toshinori Shimanouchi, Kazuhiko Ino, Kenji Uchimura, Kazuchika Nishitsuji
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 117 Issue: 52 Pages: 33225-33234
- DOI
  10.1073/pnas.2009931117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-17H03979
[Journal Article] A novel amphipathic cell-penetrating peptide based on the N-terminal glycosaminoglycan binding region of human apolipoprotein E2019
- Author(s)
  Ohgita Takashi、Takechi-Haraya Yuki、Nadai Ryo、Kotani Mana、Tamura Yuki、Nishikiori Karin、Nishitsuji Kazuchika、Uchimura Kenji、Hasegawa Koki、Sakai-Kato Kumiko、Akaji Kenichi、Saito Hiroyuki
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1861 Issue: 3 Pages: 541-549
- DOI
  10.1016/j.bbamem.2018.12.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08749, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-15K21774
[Journal Article] Biophysical Mechanism of Protein Export by Bacterial Type III Secretion System2019
- Author(s)
  Ohgita T, Saito H
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 4 Pages: 341-344
- DOI
  10.1248/cpb.c18-00947
- NAID
  130007621736
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18529, KAKENHI-PROJECT-17H03979
[Journal Article] The Accumulation of Heparan Sulfate S-Domains in Kidney Transthyretin Deposits Accelerates Fibril Formation and Promotes Cytotoxicity2019
- Author(s)
  Kameyama H, Uchimura K, Yamashita T, Kuwabara K, Mizuguchi M, Hung SC, Okuhira K, Masuda T, Kosugi T, Ohgita T, Saito H, Ando Y, Nishitsuji K.
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 189 Issue: 2 Pages: 308-319
- DOI
  10.1016/j.ajpath.2018.09.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-17K09694, KAKENHI-PROJECT-17K16123
[Journal Article] Two-step FRET as a tool for probing the amyloid state of proteins.2019
- Author(s)
  Gorbenko G., Trusova V., Gadjev N., Deligeorgiev T., Mizuguchi C., and Saito H.
- Journal Title
  
  J. Mol. Liquids
  
  Volume: 294 Pages: 111675-111675
- DOI
  10.1016/j.molliq.2019.111675
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03979
[Journal Article] Refining Calibration Procedures of Circular Dichroism Spectrometer to Improve Usability2019
- Author(s)
  K. Sakai-Kato,* K. Yoshida, T. Ohgita, Y. Takechi-Haraya, Y. Demizu, H. Saito
- Journal Title
  
  Anal. Sci.
  
  Volume: 35 Issue: 11 Pages: 1275-1278
- DOI
  10.2116/analsci.19N022
- NAID
  130007743081
- ISSN
  0910-6340, 1348-2246
- Year and Date
  2019-11-10
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-17H03979
[Journal Article] Mechanisms of Aggregation and Fibril Formation of the Amyloidogenic N-terminal Fragment of Apolipoprotein A-I2019
- Author(s)
  Mizuguchi C., Nakagawa M., Namba N., Sakai M., Kurimitsu N., Suzuki A., Fujita K., Horiuchi S., Baba T., Ohgita T., Nishitsuji K., and Saito H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 294 Issue: 36 Pages: 13515-13524
- DOI
  10.1074/jbc.ra119.008000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03979
[Journal Article] Effect of Phosphatidylserine and Cholesterol on Membrane-mediated Fibril Formation by the N-terminal Amyloidogenic Fragment of Apolipoprotein A-I2018
- Author(s)
  Mizuguchi Chiharu、Nakamura Mitsuki、Kurimitsu Naoko、Ohgita Takashi、Nishitsuji Kazuchika、Baba Teruhiko、Shigenaga Akira、Shimanouchi Toshinori、Okuhira Keiichiro、Otaka Akira、Saito Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 5497-5497
- DOI
  10.1038/s41598-018-23920-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02611, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-17K19492, KAKENHI-PROJECT-17K16123
[Journal Article] Current Understanding of Physicochemical Mechanisms for Cell Membrane Penetration of Arginine-rich Cell Penetrating Peptides: Role of Glycosaminoglycan Interactions2018
- Author(s)
  Takechi-Haraya Yuki、Saito Hiroyuki
- Journal Title
  
  Current Protein & Peptide Science
  
  Volume: 19 Issue: 6 Pages: 623-630
- DOI
  10.2174/1389203719666180112100747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03979
[Journal Article] Lipid Bilayer Interactions of Amyloidogenic N-Terminal Fragment of Apolipoprotein A-I Probed by F?rster Resonance Energy Transfer and Molecular Dynamics Simulations2018
- Author(s)
  Gorbenko Galyna P.、Trusova Valeriya、Mizuguchi Chiharu、Saito Hiroyuki
- Journal Title
  
  Journal of Fluorescence
  
  Volume: 28 Issue: 5 Pages: 1037-1047
- DOI
  10.1007/s10895-018-2267-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03979
[Journal Article] Immunochemical Approach for Monitoring of Structural Transition of ApoA-I upon HDL Formation Using Novel Monoclonal Antibodies2017
- Author(s)
  H. Kimura, S. Mikawa, C. Mizuguchi, Y. Horie, I. Morita, H. Oyama, T. Ohgita, K. Nishitsuji, A. Takeuchi, S. Lund-Katz, K. Akaji, N. Kobayashi, H. Saito
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 2988-2988
- DOI
  10.1038/s41598-017-03208-8
- NAID
  120006534990
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08953, KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-15K08629
[Journal Article] Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.2017
- Author(s)
  Okuhira, K., Shoda, T., Omura, R., Ohoka, N., Hattori, T., Shibata, N., Demizu, Y., Sugihara, R., Ichino, A., Kawahara, H., Itoh, Y., Ishikawa, M., Hashimoto, Y., Kurihara, M., Itoh, S., Saito, H. & Naito, M.
- Journal Title
  
  Mol pharmacol
  
  Volume: 91 Issue: 3 Pages: 159-166
- DOI
  10.1124/mol.116.105569
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05090, KAKENHI-PROJECT-25293027, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-26460169, KAKENHI-PROJECT-16K15121, KAKENHI-PROJECT-16K18916, KAKENHI-PROJECT-16K08340, KAKENHI-PROJECT-17H03979
[Journal Article] Fluorescence study of the effect of the oxidized phospholipids on amyloid fibril formation by the apolipoprotein A-I N-terminal fragment2017
- Author(s)
  Vus Kateryna、Girych Mykhailo、Trusova Valeriya、Gorbenko Galyna、Kinnunen Paavo、Mizuguchi Chiharu、Saito Hiroyuki
- Journal Title
  
  Chem. Phys. Lett.
  
  Volume: 688 Pages: 1-6
- DOI
  10.1016/j.cplett.2017.09.037
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-16J01828
[Journal Article] Glycosaminoglycan Binding and Non-endocytic Membrane Translocation of Cell-permeable Octaarginine Monitored by Real Time In-cell NMR Spectroscopy2017
- Author(s)
  Y. Takechi-Haraya, K. Aki, Y. Tohyama, Y. Harano, T. Kawakami, H. Saito, E. Okamura
- Journal Title
  
  Pharmaceuticals
  
  Volume: 10 Issue: 2 Pages: 42-60
- DOI
  10.3390/ph10020042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K05254, KAKENHI-PROJECT-15K05401, KAKENHI-PROJECT-17H03979
[Journal Article] Combined thioflavin T - Congo red fluorescence assay for amyloid fibril detection2016
- Author(s)
  Girych, M., Gorbenko, G., Maliyov, I., Trusova, V., Mizuguchi, C., Saito, H., Kinnunen, P.
- Journal Title
  
  Methods and Applications in Fluorescence
  
  Volume: 4(3) Issue: 3 Pages: 034010-034010
- DOI
  10.1088/2050-6120/4/3/034010
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-25293006
[Journal Article] Enzymatic Remodeling of Heparan Sulfate: A Therapeutic Strategy for Systemic and Localized Amyloidoses?2016
- Author(s)
  Nishitsuji K. Saito H., and Uchimura K.
- Journal Title
  
  Neur. Regener. Res.
  
  Volume: 11 Issue: 3 Pages: 408-409
- DOI
  10.4103/1673-5374.179043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-15K08265
[Journal Article] The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity.2016
- Author(s)
  Nakajima H, Nishitsuji K, Kawashima H, Kuwabara K, Mikawa S, Uchimura K, Akaji K, Kashiwada Y, Kobayashi N, Saito H, Sakashita N
- Journal Title
  
  Amyloid
  
  Volume: 23 Issue: 1 Pages: 17-25
- DOI
  10.3109/13506129.2015.1113167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08265, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-15K08629, KAKENHI-PROJECT-16K08712
[Journal Article] Conformational Plasticity of JRAB/MICAL-L2 Provides 'Law and Order'2016
- Author(s)
  A. Sakane, S. Yoshizawa, M. Nishimura, Y. Tsuchiya, N. Matsushita, K. Miyake, K. Horikawa, I. Imoto, C. Mizuguchi, H. Saito, T. Ueno, S. Matsushita, H. Haga, S. Deguchi, K. Mizuguchi, H.
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 27 Issue: 20 Pages: 3095-3108
- DOI
  10.1091/mbc.e16-05-0332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05858, KAKENHI-PLANNED-15H05954, KAKENHI-PROJECT-15H03004, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26460370, KAKENHI-PROJECT-15K15084, KAKENHI-PROJECT-16K12872, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856
[Journal Article] Enthalpy-driven interactions with sulfated glycosaminoglycans promote cell membrane penetration of arginine peptides2016
- Author(s)
  Takechi-Haraya, Y., Nadai, R., Kimura, H., Nishitsuji, K., Uchimura, K., Sakai-Kato, K., Kawakami, K. Shigenaga, A., Kawakami, T., Otaka, A., Hojo, H., Sakashita, N., and Saito, H.
- Journal Title
  
  BBA - Biomembranes
  
  Volume: 1858 Pages: 1339-1349
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293006
[Journal Article] Dependence of intestinal absorption profile of insulin on carrier morphology composed of β-cyclodextrin-grafted chitosan2016
- Author(s)
  Yuki Daimon; Noriyasu Kamei; Kohsaku Kawakami; Mariko Takeda-Morishita; Hironori Izawa; Yuki Takechi-Haraya; Hiroyuki Saito; Hideki Sakai; Masahiko Abe; Katsuhiko Ariga
- Journal Title
  
  Mol. Pharmaceutics
  
  Volume: 13 Issue: 12 Pages: 4034-4042
- DOI
  10.1021/acs.molpharmaceut.6b00561
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06518, KAKENHI-PROJECT-25293006
[Journal Article] Iowa Mutant Apolipoprotein A-I (ApoA-IIowa) Fibrils Target Lysosomes.2016
- Author(s)
  Kameyama H., Nakajima H., Nishitsuji K., Mikawa S., Uchimura K., Kobayashi N., Okuhira K., Saito H., and Sakashita N.
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 30391-30391
- DOI
  10.1038/srep30391
- NAID
  120006534966
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-15K08629, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-16K08712, KAKENHI-PROJECT-15K08265
[Journal Article] Formation of stable nanodiscs by bihelical apolipoprotein A-I mimetic peptide2016
- Author(s)
  Kariyazono, H., Nadai, R., Miyajima, R., Takechi-Haraya, Y., Baba, T., Shigenaga, A., Okuhira, K., Otaka, A., and Saito, H.
- Journal Title
  
  J. Peptide Sci.
  
  Volume: 22 Issue: 2 Pages: 116-122
- DOI
  10.1002/psc.2847
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-16K08236
[Journal Article] Heparin promotes fibril formation by the N-terminal fragment of amyloidogenic apolipoprotein A-I2016
- Author(s)
  Mikawa, S., Mizuguchi, C., Nishitsuji, K., Baba, T., Shigenaga,A., Shimanouchi, T., Sakashita, N., Otaka, A., Akaji, K., Saito, H.
- Journal Title
  
  FEBS Letters
  
  Volume: 590(20) Issue: 20 Pages: 3492-3500
- DOI
  10.1002/1873-3468.12426
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-16K08712
[Journal Article] The novel functional nucleic acid iRed effectively regulates target genes following cytoplasmic delivery by faint electric treatment2016
- Author(s)
  Mahadi Hasan, Noriko Tarashima, Koki Fujikawa, Takashi Ohgita, Susumu Hama, Tamotsu Tanaka, Hiroyuki Saito, Noriaki Minakawa, Kentaro Kogure
- Journal Title
  
  Science and Technology of Advanced Materials
  
  Volume: 17 Issue: 1 Pages: 554-562
- DOI
  10.1080/14686996.2016.1221726
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-WRAPUP-16H01692, KAKENHI-PROJECT-15H04656, KAKENHI-PROJECT-15H06446, KAKENHI-PROJECT-25293006
[Journal Article] Molecular complex composed of β-cyclodextrin-grafted chitosan and pH-sensitive amphipathic peptide for enhancing cellular cholesterol efflux under acidic pH.2015
- Author(s)
  Takechi-Haraya, Y., Tanaka, K., Tsuji, K., Asami, Y., Izawa, H., Shigenaga, A., Otaka, A., Saito, H., and Kawakami, K.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 26 Issue: 3 Pages: 572-581
- DOI
  10.1021/acs.bioconjchem.5b00037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293006
[Journal Article] K604, a specific acyl-CoA:CoA:cholesterol acyltransferase 1 inhibitor, suppresses proliferation of U251-MG glioblastoma cells2015
- Author(s)
  Ohmoto, Takuji Nishitsuji, Kazuchika Yoshitani, Nobuyuki Mizuguchi, Makoto Yanagisawa, Yuto Saito, Hiroyuki Sakashita, Naomi
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 12 Issue: 4 Pages: 6037-6042
- DOI
  10.3892/mmr.2015.4200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-26670190, KAKENHI-PROJECT-25293006
[Journal Article] Membrane Effects of N-Terminal Fragment of Apolipoprotein A-I: A Fluorescent Probe Study.2015
- Author(s)
  Trusova, V., Gorbenko, G., Girych, M., Adachi, E., Mizuguchi, C., Sood, R., Kinnunen, P., and Saito, H.
- Journal Title
  
  J. Fluoresc.
  
  Volume: 25 Issue: 2 Pages: 253-261
- DOI
  10.1007/s10895-015-1501-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293006
[Journal Article] Cellular Interaction and Cytotoxicity of the Iowa Mutation of Apolipoprotein A-I (ApoA-IIowa) Amyloid Mediated by Sulfate Moieties of Heparan Sulfate2015
- Author(s)
  Kuwabara, K., Nishitsuji, K., Uchimura, K., Hung, S.C., Mizuguchi, M., Nakajima, H., Mikawa, S., Kobayashi, N., Saito, H., and Sakashita, N.
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 40 Pages: 24210-24221
- DOI
  10.1074/jbc.m115.652545
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08265, KAKENHI-PROJECT-15K08629, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-25460709, KAKENHI-PROJECT-25293006
[Journal Article] Amyloidogenic Mutation Promotes Fibril Formation of the N-terminal Apolipoprotein A-I on Lipid Membranes.2015
- Author(s)
  Mizuguchi, C., Ogata, F., Mikawa, S., Tsuji, K., Baba, T., Shigenaga, A., Shimanouchi, T., Okuhira, K., Otaka, A., and Saito, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 34 Pages: 20947-20959
- DOI
  10.1074/jbc.m115.664227
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293006
[Journal Article] FRET evidence for untwisting of amyloid fibrils on the surface of model membranes2015
- Author(s)
  Gorbenko, G., Trusova, V., Girych, M., Adachi, E., Mizuguchi, C., Akaji, K., and Saito, H.
- Journal Title
  
  Soft Matter
  
  Volume: 11 Issue: 31 Pages: 6223-6234
- DOI
  10.1039/c5sm00183h
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293006
[Journal Article] Kinetic and Thermodynamic Analyses of Spontaneous Exchange between High Density Lipoprotein-Bound and Lipid-Free Apolipoprotein A-I.2015
- Author(s)
  Handa, D., Kimura, H., Oka, T., Takechi, Y., Okuhira, K., Phillips, M. C., and Saito, H.
- Journal Title
  
  Biochemistry
  
  Volume: 54 Issue: 4 Pages: 1123-1131
- DOI
  10.1021/bi501345j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-25670014
[Journal Article] Direct detection of ABCA1-dependent HDL formation based on lipidation-induced hydrophobicity change in apoA-I.2014
- Author(s)
  Risa Omura, Kohjiro Nagao, Norihiro Kobayashi, Kazumitsu Ueda, and Hiroyuki Saito
- Journal Title
  
  J Lipid Res.
  
  Volume: 55 Issue: 11 Pages: 2423-2431
- DOI
  10.1194/jlr.d049445
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-25460709, KAKENHI-PROJECT-25670014, KAKENHI-PROJECT-25670280, KAKENHI-PROJECT-25850070
[Journal Article] Fluorescence Study of Domain Structure and Lipid Interaction of Human Apolipoproteins E3 and E4.2014
- Author(s)
  Mizuguchi, C., Hata, M., Dhanasekaran, P., Nickel, M., Phillips, M. C., Lund-Katz, S., and Saito, H.
- Journal Title
  
  Biochim. Biophys. Acta - Mol. Cell Biol. Lipids
  
  Volume: 1841 Issue: 12 Pages: 1716-1724
- DOI
  10.1016/j.bbalip.2014.09.019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-25670014
[Journal Article] Interaction of Thioflavin T with Amyloid Fibrils of Apolipoprotein A-I N-terminal Fragment: Resonance Energy Transfer Study.2014
- Author(s)
  Girych, M., Gorbenko, G., Trusova, V., Adachi, E., Mizuguchi, C., Nagao, K., Kawashima, H., Akaji, K., Lund-Katz, S., Phillips, M. C., and Saito, H.
- Journal Title
  
  J. Struct. Biol.
  
  Volume: 185 Issue: 1 Pages: 116-124
- DOI
  10.1016/j.jsb.2013.10.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-25670014, KAKENHI-PROJECT-25850070
[Journal Article] The Extreme N-terminal Region of Human Apolipoprotein A-I Has a Strong Propensity to Form Amyloid Fibrils2014
- Author(s)
  Adachi, E., Kosaka, A., Tsuji, K., Mizuguchi, C., Kawashima, H., Shigenaga, A., Nagao, K., Akaji, K., Otaka, A., and Saito, H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 588 Issue: 3 Pages: 389-394
- DOI
  10.1016/j.febslet.2013.11.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-25670014, KAKENHI-PROJECT-25850070
[Journal Article] The roles of C-terminal helices of human apolipoprotein A-I in formation of high-density lipoprotein particles.2014
- Author(s)
  Nagao, K., Hata, M., Tanaka, K., Takechi, Y., Nguyen, D., Dhanasekaran, P., Lund-Katz, S., Phillips, M. C., and Saito, H.
- Journal Title
  
  Biochim. Biophys. Acta-Mol. Cell Biol. Lipids
  
  Volume: 1841 Issue: 1 Pages: 80-87
- DOI
  10.1016/j.bbalip.2013.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-25670014, KAKENHI-PROJECT-25850070
[Journal Article] Influence of Domain Stability on the Properties of Human Apolipoprotein E3 and E4 and Mouse Apolipoprotein E.2014
- Author(s)
  Nguyen, D., Dhanasekaran, P., Nickel, M., Mizuguchi, C., Watanabe, M., Saito, H., Phillips, M. C., and Lund-Katz, S
- Journal Title
  
  Biochemistry
  
  Volume: 53 Issue: 24 Pages: 4025-4033
- DOI
  10.1021/bi500340z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-25670014
[Journal Article] Slow Tumbling but Large Protrusion of Phospholipids in the Cell Sized Giant Vesicle.2013
- Author(s)
  Takechi, Y., Saito, H., and Okamura, E
- Journal Title
  
  Chem. Phys. Lett
  
  Volume: 570 Pages: 136-140
- DOI
  10.1016/j.cplett.2013.03.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046, KAKENHI-PROJECT-24550035, KAKENHI-PROJECT-25293006
[Journal Article] Interactions of Apolipoprotein A-I with High Density Lipoprotein Particles2013
- Author(s)
  Nguyen, D., Nickel, M., Mizuguchi, C., Saito, H., Lund-Katz, S., and Phillips, M. C
- Journal Title
  
  Biochemistry
  
  Volume: 52(11) Issue: 11 Pages: 1963-1972
- DOI
  10.1021/bi400032y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046, KAKENHI-PROJECT-25293006
[Journal Article] Dual role of an N-terminal amyloidogenic mutationin apolipoprotein A-I.2013
- Author(s)
  足立愛美
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 228 Issue: 4 Pages: 2848-2856
- DOI
  10.1074/jbc.m112.428052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08493, KAKENHI-PROJECT-22590046, KAKENHI-PROJECT-25293006
[Journal Article] Effect of Amino Acid Distribution of Amphipathic Helical Peptide Derived from Human Apolipoprotein A-I on Membrane Curvature Sensing.2013
- Author(s)
  Tanaka, M., Takamura, Y., Kawakami, T., Aimoto, S., Saito, H., and Mukai, T
- Journal Title
  
  FEBS Lett
  
  Volume: 587(5) Issue: 5 Pages: 510-515
- DOI
  10.1016/j.febslet.2013.01.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046, KAKENHI-PROJECT-25293006
[Journal Article] Influence of C-Terminal α-Helix Hydrophobicity and Aromatic Amino Acid Content on Apolipoprotein A-I Functionality.2012
- Author(s)
  Lyssenko, N. N., Hata, M., Dhanasekaran, P., Nickel, M., Chetty, P. S., Saito, H., Lund-KatzS., and Phillips, M. C
- Journal Title
  
  Biochim. Biophys. Acta-Mol. Cell Biol. Lipids
  
  Volume: 1821(3) Issue: 3 Pages: 456-463
- DOI
  10.1016/j.bbalip.2011.07.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Comparative Study on the Interaction of Cell-Penetrating Polycationic Polymers with Lipid Membranes2012
- Author(s)
  Takechi, Y., Tanaka, H., Kitayama, H., Yoshii, H., Tanaka, M., and Saito, H
- Journal Title
  
  Chem. Phys. Lipids
  
  Volume: 165(1) Issue: 1 Pages: 51-58
- DOI
  10.1016/j.chemphyslip.2011.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Physicochemical Mechanism for the Lipid Membrane Binding of Polyarginine: the Favorable Enthalpy Change with Structural Transition from Random Coil to α-Helix2012
- Author(s)
  Takechi, Y., Mizuguchi, C., Tanaka, M., Kawakami, T., Aimoto, S., Okamura, E., and Saito, H
- Journal Title
  
  Chem. Lett
  
  Volume: 41(10) Issue: 10 Pages: 1374-1376
- DOI
  10.1246/cl.2012.1374
- NAID
  10031120691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046, KAKENHI-PROJECT-24550035
[Journal Article] Fluorescence Analysis of the Lipid Binding-induced Conformational Change of Apolipoprotein E42012
- Author(s)
  Mizuguchi, C., Hata, M., Dhanasekaran, P.,Nickel, M., Phillips, M. C., Lund-Katz, S., and Saito, H
- Journal Title
  
  Biochemistry
  
  Volume: 51(28) Issue: 28 Pages: 5580-5588
- DOI
  10.1021/bi300672s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Effects of the Iowa and Milano Mutations on Apolipoprotein A-I Structure and Dynamics Determined by Hydrogen Exchange and Mass Spectrometry2012
- Author(s)
  Chetty, P. S., Ohshiro, M., Saito, H., Dhanasekaran, P., Lund-Katz, S., Mayne, L., Englander, W., and Phillips, M. C
- Journal Title
  
  Biochemistry
  
  Volume: 51(44) Issue: 44 Pages: 8993-9001
- DOI
  10.1021/bi300926j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Influence of N-Terminal Helix Bundle Stability on the Lipid-Binding Properties of Human Apolipoprotein A-I.2011
- Author(s)
  Tanaka, M., Dhanasekaran, P., Nguyen, D., Nickel, M., Takechi, Y., Lund-Katz, S., Phillips, M. C., and Saito, H
- Journal Title
  
  Biochim. Biophys. Acta-Mol. Cell Biol. Lipids
  
  Volume: 1811(1) Issue: 1 Pages: 25-30
- DOI
  10.1016/j.bbalip.2010.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Physicochemical Mechanism for the Enhanced Ability of Lipid Membrane Penetration of Polyarginine2011
- Author(s)
  Takechi, Y., Yoshii, H., Tanaka, M., Kawakami, T., Aimoto, S., and Saito, H
- Journal Title
  
  Langmuir
  
  Volume: 27(11) Issue: 11 Pages: 7099-7107
- DOI
  10.1021/la200917y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Identification of Regions Responsible for Heparin-Induced Amyloidogenesis of Human Serum Amyloid A Using Its Fragment Peptides.2011
- Author(s)
  Egashira, M., Takase, H., Yamamoto, I., Tanaka, M., and Saito, H
- Journal Title
  
  Arch. Biochem. Biophys
  
  Volume: 511(1-2) Issue: 1-2 Pages: 101-106
- DOI
  10.1016/j.abb.2011.04.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Surface Plasmon Resonance Analysis of the Mechanism of Binding of ApoA-I to High Density Lipoprotein Particles.2010
- Author(s)
  Lund-Katz, S., Nguyen, D., Dhanasekaran, P., Kono, M., Nickel, M., Saito, H., and Phillips, M. C
- Journal Title
  
  J. Lipid Res
  
  Volume: 51(3) Issue: 3 Pages: 606-617
- DOI
  10.1194/jlr.m002055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Molecular Basis for the Differences in Lipid and Lipoprotein Binding Properties of Human Apolipoproteins E3 and E42010
- Author(s)
  Nguyen, D., Dhanasekaran, P., Nickel, M., Nakatani, R., Saito, H., Phillips, M. C., and Lund-Katz, S
- Journal Title
  
  Biochemistry
  
  Volume: 49(51) Issue: 51 Pages: 10881-10889
- DOI
  10.1021/bi1017655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Disruption of the C-terminal Helix by Single Amino Acid Deletion is Directly Responsible for Impaired Cholesterol Efflux Ability of Apolipoprotein A-I Nichinan.2010
- Author(s)
  Kono, M., Tanaka, T., Tanaka, M., Vedhachalam, C., Chetty, P. S., Nguyen, D., Dhanasekaran, P., Lund-Katz, S., Phillips, M. C., and Saito, H
- Journal Title
  
  J. Lipid Res
  
  Volume: 51(4) Issue: 4 Pages: 809-818
- DOI
  10.1194/jlr.m002113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590046
[Journal Article] Underlying Apolipoprotein E (ApoE) Isoform-Dependent Lipid Efflux from Neural Cells in Culture.2009
- Author(s)
  Watanabe, A., Lund-Katz, S., Phillips, M. C., Saito, H., Michikawa, M., Mechanism
- Journal Title
  
  J. Neurosci. Res. in press
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Evaluation of Lipid-Binding Properties of the N-Terminal Helical Segments in Human Apolipoprotein A-I Using Fragment Peptides.2009
- Author(s)
  Tanaka, M., Tanaka, T., Ohta, S., Kawakami, T., Konno, H., Akaji, K., Aimoto, S., and Saito, H.
- Journal Title
  
  J. Peptide Sci. 15
  
  Pages: 36-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Interaction between the N- and C-Terminal Domains Modulates the Stability and Lipid Binding of Apolipoprotein A-I.2009
- Author(s)
  Koyama, M., Tanaka, M., Dhanasekaran, P., Lund-Katz, S., Phillips, M. C., Saito, H.
- Journal Title
  
  Biochemistry 48
  
  Pages: 2529-2537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Contributions of the Carboxyl-Terminal Helical Segment to the Self-Association and Lipoprotein Preferences of Human Apolipoprotein E3 and E4 Isoforms.2008
- Author(s)
  Sakamoto, T., Tanaka, M., Vedhachalam, C., Nickel, M., Nguyen, D., Dhanasekaran, P., Phillips, M. C., Lund-Katz, S., Saito, H.
- Journal Title
  
  Biochemistry 47
  
  Pages: 2968-2977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Conformational Change of Apolipoprotein A-I and HDL Formation from Model Membranes under Intercellular Acidic Conditions.2008
- Author(s)
  Fukuda, M., Nakano, M., Miyazaki, M., Tanaka, M., Saito, H., Kobayashi, S., Ueno, M., Handa, T.
- Journal Title
  
  J. Lipid Res. 49
  
  Pages: 2419-2426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Conformational Flexibility of the N-terminal Domain of Apolipoprotein A-I Bound to Spherical Lipid Particles.2008
- Author(s)
  Kono, M., Okumura, Y., Tanaka, M., Nguyen, D., Dhanasekaran, P., Lund-Katz, S., Phillips, M. C., Saito, H.
- Journal Title
  
  Biochemistry 47
  
  Pages: 11340-11347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Influence of Tertiary Structure Domain Properties on the Functionality of Apolipoprotein A-I.2008
- Author(s)
  Tanaka, M., Koyama, M., Dhanasekaran, P., Nguyen, D., Nickel, M., Lund-Katz, S., Saito, H., Phillips, M. C.
- Journal Title
  
  Biochemistry 47
  
  Pages: 2127-2180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Evaluation of Peptide-Aldehyde Inhibitors Using R188I Mutant of SARS 3CL Protease as a Proteolysis-Resistant Mutant.2008
- Author(s)
  Akaji, K., Konno, H., Onozuka, M., Makino, A., Saito, H., Nosaka, K.
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 9400-9408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Chk1 Is a Histone H3 Threonine 11 Kinase that Regulates DNA Damage-Induced Transcriptional Repression.2008
- Author(s)
  Shimada, M., Niida, H., Zineldeen, D. H., Tagami, H., Tanaka, M., Saito, H., Nakanishi, M.
- Journal Title
  
  Cell 132
  
  Pages: 221-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Role of the N- and C-Terminal Domains in Binding of Apolipoprotein E Isoforms to Heparan Sulfate and Dermatan Sulfate: A Surface Plasmon Study.2008
- Author(s)
  Yamauchi, Y., Deguchi, N., Takagi, C., Tanaka, M., Dhanasekaran, P., Nakano, M., Handa, T., Phillips, M. C., Lund-Katz, S., Saito, H.
- Journal Title
  
  Biochemistry 47
  
  Pages: 6702-6710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Journal Article] Mechanism of ATP-Binding Cassette Transporter A1 (ABCA1)-mediated Cellular Lipid Efflux to Apolipoprotein A-I and Formation of High Density Lipoprotein Particles.2007
- Author(s)
  Vedhachalam, C., Duong, P.T., Nickel, M., Nguyen, D., Dhanasekaran, P., Saito, H., Rothblat, G.H., Lund-Katz, S., Phillips, M. C.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 25123-25130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] 炭酸脱水酵素によるリン脂質の脂肪酸組成の制御2024
- Author(s)
  松本佳菜，長尾耕治郎，斎藤博幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] アポリポタンパク質E由来両親媒性ペプチドの脂質膜相互作用および細胞通過へ及ぼすコンフォメーション制限の影響2024
- Author(s)
  原矢佑樹，扇田隆司，臼井明子，西辻和親，内村健治，阿部康弘，川野竜司，Monika I. Konaklieva，Mart Reimund，Alan T. Remaley，佐藤陽治，伊豆津健一，斎藤博幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] カイロミクロンタンパク質apoA-IVのアミロイド線維形成の物理化学的メカニズム2024
- Author(s)
  南波憲宏，段上時子，北川裕一朗，扇田隆司，島内寿徳，斎藤博幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] 生合成酵素の局在に着目したリン脂質組成の制御機構の解明2024
- Author(s)
  平岡優里佳，宮田友花，長尾耕治郎，斎藤博幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] ABCA1による高密度リポタンパク質形成に一価不飽和脂肪酸含有リン脂質が与える影響2024
- Author(s)
  松尾茉祐，南波憲宏，長尾耕治郎，斎藤博幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] パーキンソン病αシヌクレインの凝集・線維化に対する脂質膜組成の影響2024
- Author(s)
  河野弘樹，南波憲宏，扇田隆司，長尾耕治郎，斎藤博幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] アミロイド共存タンパク質アポA-IVの物性とアミロイド線維形成促進効果2023
- Author(s)
  内藤禎人、南波憲宏、扇田隆司、斎藤博幸
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] アミロイド形成タンパク質の凝集核形成特性の速度論的解析2023
- Author(s)
  扇田隆司、南波憲宏、河野弘樹、斎藤博幸
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] ライトシート顕微鏡を用いたα-シヌクレインの脳内伝播の空間的可視化法の解析2023
- Author(s)
  宗野虎滋、西村周泰、扇田隆司、伊東春香、斎藤博幸、高田和幸
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] Amyloidogenic mutation of the N-terminal fragment of apolipoprotein A-I generates a new aggregation-prone segment that acts as an entropic driver of aggregation2023
- Author(s)
  Norihiro Namba, Takashi Ohgita, Hiroko Tamagaki-Asahina, Toshinori Shimanouchi, Takeshi Sato, Hiroyuki Saito
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] Bacopa monnieraに含有されるAβ結合物質plantainoside BによるAβ凝集体の検出と神経保護作用2023
- Author(s)
  福田愛菜、中嶋聡一、尾田好美、西村周泰、河嶋秀和、木村寛之、扇田隆司、河下映里、石原慶一、花木葵、岡崎瑞紀、松田英里香、田中雪衣、中村誠宏、松本崇宏、秋葉聡、斎藤博幸、松田久司、高田和幸
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] 新規抗アポEモノクローナル抗体のアポEアイソフォーム反応特性の物理化学的評価2023
- Author(s)
  坂井瑚都、福井和華、南波憲宏、扇田隆司、木口裕貴、森田いずみ、大山浩之、長尾耕治郎、小林典裕、斎藤博幸
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] 脳に生着したヒトiPS細胞由来神経細胞へのα-シヌクレイン伝播の組織学的評価2023
- Author(s)
  西村周泰、儀間芹菜、扇田隆司、斎藤博幸、高田和幸
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] ApoA-Iの構造安定性とアミロイド線維形成性に及ぼすアミロイドーシス変異の影響2023
- Author(s)
  南波憲宏、上野美羽、朝比奈裕子、扇田隆司、島内寿徳、佐藤毅、斎藤博幸
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] カイロミクロンタンパク質apoA-IVのN末フラグメントは強いアミロイド凝集特性を有する2023
- Author(s)
  北川裕一朗、内藤禎人、南波憲宏、扇田隆司、斎藤博幸
- Organizer
  第73回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] 形質膜ホスファチジルセリンの組成制御機構2023
- Author(s)
  越智彩乃、長尾耕治郎、斎藤博幸
- Organizer
  第73回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] シクロスポリン類縁体と細胞膜モデルとの相互作用に関する研究2022
- Author(s)
  中尾瑞佳、原矢佑樹、扇田隆司、斎藤博幸、出水庸介、伊豆津健一、加藤くみ子
- Organizer
  第29回クロマトグラフィーシンポジウム
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] アミロイドーシス変異によるapoA-Iの凝集・線維化促進機構の解明2022
- Author(s)
  南波憲宏、扇田隆司、島内寿徳、斎藤博幸
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] αシヌクレインの線維化及び細胞毒性に対する高凝集性領域の寄与2022
- Author(s)
  河野弘樹、鎌田真央、南波憲宏、扇田隆司、森田いずみ、大山浩之、長尾耕治郎、小林典裕、斎藤博幸
- Organizer
  第70回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] 両親媒性アルギニンペプチドの脂質膜相互作用および細胞膜透過に及ぼす疎水性モーメントの影響2022
- Author(s)
  原矢佑樹、扇田隆司、小谷真菜、河野弘樹、斉藤千尋、朝比奈裕子、西辻和親、内村健治、佐藤毅、川野竜司、加藤くみ子、伊豆津健一、斎藤博幸
- Organizer
  日本膜学会第44年会
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] 脂質膜環境におけるヒト及びマウスαシヌクレインの凝集・線維化挙動2022
- Author(s)
  扇田隆司、河野弘樹、島内寿德、斎藤博幸
- Organizer
  膜シンポジウム2022
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] 第9回日本アミロイドーシス研究会学術集会2022
- Author(s)
  南波憲宏、扇田隆司、島内寿德、斎藤博幸
- Organizer
  アミロイドーシス変異apoA-Iの線維核形成はエントロピー駆動的に促進される
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] ヒトとマウス間の比較によるαシヌクレイン線維化制御機構の解析2022
- Author(s)
  扇田隆司、河野弘樹、森田いずみ、大山浩之、島内寿徳、小林典裕、斎藤博幸
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] ApoA-Iアミロイド線維形成過程の速度論的並びに熱力学的解析2022
- Author(s)
  南波憲宏、扇田隆司、島内寿徳、斎藤博幸
- Organizer
  第19回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-22K06556
[Presentation] 新規抗アポA-Iアミロイド抗体は配列非依存的に線維構造を認識する2021
- Author(s)
  中野未悠、扇田隆司、森田いずみ、大山浩之、小林典裕、斎藤博幸
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Effects of Parkinson’s Disease-Related Familial Mutation and C-terminal Truncation on Nucleation and Fibril Elongation of α-Synuclein2021
- Author(s)
  Ohgita T., Mamba N., Kono H., Saito H.
- Organizer
  Biophysical Society 65th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] パーキンソン病変異又はC末欠損によるαシヌクレインアミロイド凝集促進機構2021
- Author(s)
  扇田隆司、南波憲宏、河野弘樹、島内寿德、斎藤博幸
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] α-シヌクレインのアミロイド凝集・線維化反応の熱力学的特性－ApoA-Iとの比較2021
- Author(s)
  南波憲宏、河野弘樹、扇田隆司、島内寿德、斎藤博幸
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] がん抑制タンパク質p53のアミロイド線維形成性2020
- Author(s)
  南波憲宏、扇田隆司、島内寿德、西辻和親、斎藤博幸
- Organizer
  第70回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ApoA-Iアミロイドのエントロピー駆動型核形成における線維化領域の寄与2020
- Author(s)
  南波憲宏、中川美穂、木村美月、坂井美冴、扇田隆司、斎藤博幸
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ホスファチジルエタノールアミンによるIowa変異型アポA-Iの凝集・線維化促進機構2020
- Author(s)
  栗光直子、水口智晴、藤田かほ、田口鈴乃、扇田隆司、島内寿徳、斎藤博幸
- Organizer
  日本膜学会第42年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] アポA-I線維形成におけるアミロイド共存タンパク質アポEの二相性効果2020
- Author(s)
  中野未悠、鎌田真央、水口智晴、扇田隆司、斎藤博幸
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ポリプロリンIIヘリックス構造によるアルギニンペプチド細胞膜透過促進機構2020
- Author(s)
  扇田隆司、原矢佑樹、岡田圭祐、松井早希、竹内美紗紀、齋藤千尋、西辻和親、内村健治、川野竜司、長谷川功紀、加藤くみ子、赤路健一、伊豆津健一、斎藤博幸
- Organizer
  膜シンポジウム2020
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ホスファチジルエタノールアミンはIowa変異型アポA-Iの線維化を促進する2020
- Author(s)
  栗光直子、水口智晴、藤田かほ、堀内爽加、扇田隆司、島内寿徳、斎藤博幸
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ポリプロリンⅡヘリックス構造によるアルギニンペプチドの細胞膜透過性の亢進2020
- Author(s)
  松井早希、岡田圭祐、竹内美紗紀、扇田隆司、原矢佑樹、西辻和親、内村健治、長谷川功紀、加藤くみ子、赤路健一、斎藤博幸
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] トランスサイレチンによるアミロイド凝集に及ぼす脂質膜の影響2020
- Author(s)
  横田舞、島内寿徳、斎藤博幸、木村幸敬
- Organizer
  膜シンポジウム2020
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ApoE糖鎖結合ドメイン改変型両親媒性アルギニンペプチドの細胞膜透過機構2019
- Author(s)
  小谷真菜、田村悠樹、扇田隆司、原矢佑樹、西辻和親、内村健治、長谷川功紀、加藤くみ子、赤路健一、斎藤博幸
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ApoE由来アルギニンペプチドの細胞膜透過における糖鎖依存性の評価2019
- Author(s)
  田村悠樹、小谷真菜、扇田隆司、原矢佑樹、西辻和親、内村健治、長谷川功紀、加藤くみ子、赤路健一、斎藤博幸
- Organizer
  日本膜学会第41年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 熱力学的解析によるIowa変異型ApoA-Iの線維化機構の解明2019
- Author(s)
  南波憲宏、中川美穂、坂井美冴、鈴木彩音、扇田隆司、斎藤博幸
- Organizer
  第69回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 両親媒性環状ペプチドの細胞膜透過機構解明に向けたペプチドの合成2019
- Author(s)
  錦織花梨、長谷川功紀、原矢佑樹、扇田隆司、加藤くみ子、赤路健一、斎藤博幸
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ApoA-Iアミロイド線維形成における各構造領域の役割に関する物理化学的解析2019
- Author(s)
  扇田隆司、中川美穂、坂井美冴、南波憲宏、鈴木彩音、藤田かほ、堀内爽加、水口智晴、斎藤博幸
- Organizer
  第7回日本アミロイドーシス研究会学術集会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] パーキンソン病原因タンパク質α-シヌクレインの作製と物性評価2019
- Author(s)
  田中翔子、平松彩羅、原田航吉、扇田隆司、斎藤博幸
- Organizer
  第69回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Iowa変異型アポA-Iのアミロイド線維形成過程に関する速度論的・熱力学的解析2019
- Author(s)
  坂井美冴、藤田かほ、堀内爽加、水口智晴、扇田隆司、斎藤博幸
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 部位特異的蛍光標識によるアポA-Iアミロイド線維詳細構造の評価2019
- Author(s)
  水口智晴、藤田かほ、堀内爽加、扇田隆司、斎藤博幸
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Heparan sulfate S-domains that accumulate in kidney transthyretin deposits accelerate fibril formation and promote cytotoxicity2019
- Author(s)
  Kazuchika Nishitsuji, Kenji Uchimura, Taro Yamashita, Kaori Kuwabara, Hirokazu Kameyama, Mineyuki Mizuguchi, Keiichiro Okuhira, Takashi Ohgita, Hiroyuki Saito, Yukio Ando
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ApoA-Iアミロイド形成過程に及ぼすApoEの濃度依存的影響2019
- Author(s)
  中野未悠、水口智晴、扇田隆司、斎藤博幸
- Organizer
  第69回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Iowa変異型アポA-Iのアミロイド線維形成機構の解明2019
- Author(s)
  水口智晴、栗光直子、中川美穂、扇田隆司、斎藤博幸
- Organizer
  第69回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] A NOVEL AMPHIPATHIC CELL-PENETRATING PEPTIDE BASED ON THE N-TERMINAL GLYCOSAMINOGLYCAN BINDING REGION OF HUMAN APOLIPOPROTEIN E2019
- Author(s)
  Yuki Tamura, Mana Kotani, Takashi Ohgita, Yuki Takechi-Haraya, Kazuchika Nishitsuji, Kenji Uchimura, Koki Hasegawa, Kumiko Sakai-Kato, Kenichi Akaji and Hiroyuki Saito
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ApoA-Iアミロイド構造を特異的に認識する新規モノクローナル抗体の開発2018
- Author(s)
  扇田隆司、服部恵美、古谷優樹、森田いずみ、大山浩之、小林典裕、斎藤博幸
- Organizer
  第6回日本アミロイドーシス研究会学術集会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 抗ApoA-I線維モノクローナル抗体の反応特異性の評価2018
- Author(s)
  服部恵美、中川美穂、原田航吉、古谷優樹、扇田隆司、森田いずみ、大山浩之、小林典裕、斎藤博幸
- Organizer
  第68回日本薬学会近畿支部大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 新規両親媒性アルギニンペプチドの細胞膜透過性の評価2018
- Author(s)
  田村悠樹、灘井亮、扇田隆司、原矢佑樹、西辻和親、内村健治、長谷川功紀、加藤くみ子、赤路健一、斎藤博幸
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 新規apoA-I構造特異抗体によるアミロイド線維反応性の評価2018
- Author(s)
  古谷優樹、服部恵美、扇田隆司、森田いずみ、大山浩之、小林典裕、斎藤博幸
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Iowa変異型アポA-Iのアミロイド形成過程における各線維化領域の役割2018
- Author(s)
  中川美穂、藤田かほ、堀内爽加、水口智晴、扇田隆司、斎藤博幸
- Organizer
  第68回日本薬学会近畿支部大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Iowa変異型アポA-Iの脂質膜相互作用・アミロイド線維化に及ぼすリン脂質組成の影響2018
- Author(s)
  水口智晴、栗光直子、扇田隆司、島内寿徳、斎藤博幸
- Organizer
  膜シンポジウム2018
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] アルギニンペプチドの両親媒性が細胞膜透過性に及ぼす影響2018
- Author(s)
  扇田隆司、灘井亮、田村悠樹、小谷真奈、田中翔子、原矢佑樹、西辻和親、内村健治、長谷川功紀、加藤くみ子、赤路健一、斎藤博幸
- Organizer
  日本膜学会第40年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] アミロイドーシス変異アポA-Iのホスファチジルセリンとの相互作用領域の特定2018
- Author(s)
  中村光希、栗光直子、水口智晴、扇田隆司、斎藤博幸
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Pathological roles of heparan sulfate S-domains in ATTR amyloidosis2018
- Author(s)
  Nishitsuji K., Uchimura K., Yamashita T., Kuwabara K., Kameyama H., Mizuguchi M., Okuhira K., Ohgita T., Saito H., Ando Y.
- Organizer
  The XVIth International Symposium on Amyloidosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Effects of Iowa (G26R) mutation on fibril formation by an amyloidogenic N-terminal fragment of apoA-I2018
- Author(s)
  Mizuguchi C., Ito E., Nakamura M., Ohgita T., Baba T., Shimanouchi T., Okuhira K., Saito H.
- Organizer
  The XVIth International Symposium on Amyloidosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ApoA-Iアミロイド線維検出のための新規構造特異抗体の開発2018
- Author(s)
  扇田隆司、古谷優樹、服部恵美、森田いずみ、大山浩之、小林典裕、斎藤博幸
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] HS S-domains that accumulate in ATTR amyloidosis patients accelerate and mediate formation and cytotoxicity of transthyretin fibrils2018
- Author(s)
  Nishitsuji K., Uchimura K., Yamashita T., Kameyama H., Kuwabara K., Mizuguchi M., Hung S.-C., Okuhira K., Ohgita T., Saito H., Ando Y.
- Organizer
  Society for Glycobiology Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 欠損変異体を用いたアポ A-Iアミロイド線維形成過程の解明2018
- Author(s)
  水口智晴、中川美穂、堀内爽加、藤田かほ、扇田隆司、奥平桂一郎、斎藤博幸
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 新規モノクローナル抗体を用いたApoA-I高次構造変化の検出2018
- Author(s)
  扇田隆司、服部恵美、古谷優樹、森田いずみ、大山浩之、小林典裕、斎藤博幸
- Organizer
  第16回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] アポA-Iアミロイド形成に対するホスファチジルエタノールアミンの影響2018
- Author(s)
  栗光直子、中村光希、水口智晴、島内寿徳、斎藤博幸
- Organizer
  第68回日本薬学会近畿支部大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 脂質膜組成によるIowa変異型アポA-Iの線維化制御メカニズムの解明2017
- Author(s)
  水口智晴，伊藤恵理子、中村光希、扇田隆司、馬場照彦，重永章，島内寿徳，奥平桂一郎，大高章，斎藤博幸
- Organizer
  膜シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Iowa変異型アポA-Iのアミロイド線維形成に及ぼすホスファチジルセリンとコレステロールの影響2017
- Author(s)
  水口智晴、伊藤恵理子、中村光希、扇田隆司、馬場照彦、島内寿德、奥平桂一郎、斎藤博幸
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] アルギニンペプチドのグリコサミノグリカン糖鎖を介した細胞膜透過機構に関する物理化学的解析2017
- Author(s)
  灘井亮，原矢佑樹，西辻和親，内村健治，加藤くみ子，重永章，川上徹，大高章，北條裕信，坂下直実，斎藤博幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ATTRアミロイドーシスにおけるヘパラン硫酸多硫酸化ドメイン（S-ドメイン）の役割の解明2017
- Author(s)
  亀山泰和、内村健治、山下太郎、水口峰之、坂下直実、斎藤博幸、奥平桂一郎、安東由喜雄、西辻和親
- Organizer
  第5回日本アミロイドーシス研究会学術集会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ATTRアミロイドーシスにおけるヘパラン硫酸多硫酸化ドメインの役割の解明2017
- Author(s)
  亀山泰和、内村健治、山下太郎、水口峰之、坂下直実、斎藤博幸、奥平桂一郎、安東由喜雄、西辻和親
- Organizer
  膜シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] 脂質膜組成によるIowa変異型アポA-Iのアミロイド線維形成性の変化2017
- Author(s)
  水口智晴、三河志穂、扇田隆司、馬場照彦、島内寿徳、奥平桂一郎、斎藤博幸
- Organizer
  日本膜学会第39年会
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] ApoA-I構造特異抗体の開発に向けた抗体評価系の確立2017
- Author(s)
  三河志穂,木村仁,扇田隆司,森田いずみ,大山浩之,小林典裕,斎藤博幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Iowa変異型アポA-Iのアミロイド形成はホスファチジルセリンによって抑制される2017
- Author(s)
  水口智晴、伊藤恵理子、中村光希、扇田隆司、馬場照彦、島内寿德、奥平桂一郎、斎藤博幸
- Organizer
  第15回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Development of Novel Conformational-specific Monoclonal Antibodies against Amyloid Fibril Form of ApoA-I2017
- Author(s)
  Yuki Furutani, Mitsuki Nakamura, Shiho Mikawa, Takashi Ohgita, Izumi Morita, Hiroyuki Oyama, Norihiro Kobayashi, Hiroyuki Saito
- Organizer
  第11回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] The Iowa mutation enhances fibril formation by an amyloidogenic N-terminal fragment of apoA-I2017
- Author(s)
  Chiharu Mizuguchi, Eriko Ito, Mitsuki Nakamura, Takashi Ohgita, Teruhiko Baba, Toshinori Shimanouchi, Keiichiro Okuhira, Hiroyuki Saito
- Organizer
  第11回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03979
[Presentation] Iowa変異型アポA-Iのアミロイド形成に及ぼす脂質組成の影響2017
- Author(s)
  水口智晴,三河志穂,馬場照彦,奥平桂一郎,斎藤博幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Cellular interaction and cytotoxicity of amyloid fibrils of the Iowa mutant of apolipoprotein A-I (apoA-IIowa) are mediated by sulfate moieties of heparan sulfate.2016
- Author(s)
  Nishitsuji K., Kuwabara K., Uchimura K., Hung SC., Kobayashi N., Saito H., Sakashita N.
- Organizer
  The XVth International Symposium on Amyloidosis
- Place of Presentation
  Uppsala Consert and Congress (Sweden)
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] SULFATED GLYCOSAMINOGLYCANS PROMOTE CELL MEMBRANE PENETRATION OF ARGININE PEPTIDES VIA ENTHALPY-DRIVEN INTERACTIONS2016
- Author(s)
  Ryo Nadai, Yuki Haraya, Kazuchika Nishitsuji, Kenji Uchimura, Kumiko Kato, Akira Shigenaga, Toru Kawakami, Akira Otaka, Hironobu Hojo, Naomi Sakashita, Hiroyuki Saito
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] HDL-apoA-I微小構造変化の検出を目的とした新規抗apoA-I抗体の開発2016
- Author(s)
  木村仁，三河志穂，森田いずみ，大山浩之，小林典裕，斎藤博幸
- Organizer
  第38回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  名古屋市立大学薬学部（愛知県名古屋市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] グリア細胞におけるABCA7発現制御機構の検討2016
- Author(s)
  市野晨人、奥平桂一郎、川原遙華、木村仁、辻大輔、西辻和親、堂前純子、道川誠、坂下直実、伊藤孝司、斎藤博幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 光応答性アポA-I模倣ペプチドの開発研究2016
- Author(s)
  川原遙華、奥平桂一郎、辻耕平、津田雄介、森本恭平、木村仁、假屋園大和、大村理沙、市野晨人、杉原涼、西辻和親、重永章、坂下直実、大高章、斎藤博幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Effect of heparin on amyloid fibril formation of apoA-I fragment peptides2016
- Author(s)
  Shiho Mikawa, Chiharu Mizuguchi, Izumi Morita, Hiroyuki Oyama, Teruhiko Baba, Akira Shigenaga, Toshinori Shimanouchi, Norihiro Kobayashi, Akira Otaka, Kenichi Akaji, and Hiroyuki Saito
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Needle-like type III secretion apparatus regulates effector transport by rotational motion2016
- Author(s)
  Takashi Ohgita, Kohei Fukuda, Kyoko Momiyama, Naoki Hayashi, Naomasa Gotoh, Hiroyuki Saito
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 腫瘍内透過性と微弱低pH応答性を併せ持つ薬物キャリアーの開発2016
- Author(s)
  松井諒、濱進、鈴木智子、板倉祥子、小暮健太朗、斎藤博幸
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ（静岡県静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アルギニンペプチドの細胞膜透過はグリコサミノグリカン糖鎖へのエンタルピー依存的結合によって促進される2016
- Author(s)
  灘井亮，原矢佑樹，西辻和親，内村健治，加藤くみ子，重永章，川上徹，大高章，北條裕信，坂下直実，斎藤博幸
- Organizer
  日本膜学会第38年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都新宿区）
- Year and Date
  2016-05-10
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Intracellular delivery of a novel functional nucleic acid iRed by faint electric treatment for effective regulation of target genes2016
- Author(s)
  Mahadi Hasan, Noriko Tarashima, Kohki Fujikawa, Takashi Ohgita, Susumu Hama, Tamotsu Tanaka, Hiroyuki Saito, Noriaki Minakawa, Kentaro Kogure.
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ（静岡県静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Iowa変異型アポA-Iによる脂質膜環境下でのアミロイド線維形成2016
- Author(s)
  水口智晴、三河志穂、馬場照彦、島内寿徳、重永章、奥平桂一郎、大高章、斎藤博幸
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ApoA-I線維はオートファジー/リソソーム系の機能を障害する2016
- Author(s)
  亀山泰和，西辻和親，小林典裕，斎藤博幸，坂下直実
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 細菌Ⅲ型分泌機構の解明を目指した分泌装置の回転-分泌相関の検討2016
- Author(s)
  扇田隆司, 林直樹, 上川翼, 籾山京子, 福田昂平, 小暮健太朗, 後藤直正, 斎藤博幸
- Organizer
  第11回トランスポーター研究会年会
- Place of Presentation
  京都大学宇治キャンパスきはだホール（京都府宇治市）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 腹腔内貯留型トコフェロールコハク酸含有ナノ粒子の腹膜播種治療への応用2016
- Author(s)
  西貴之、濱進、西本明功、鈴木智子、桐村直子、斎藤博幸、福澤健治、小暮健太朗
- Organizer
  日本ビタミン学会第68回大会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] タンパク質分泌の新規リアルタイム評価系を用いた細菌Ⅲ型分泌メカニズムの検討2016
- Author(s)
  扇田隆司、林直樹、後藤直正、小暮健太朗、斎藤博幸
- Organizer
  日本膜学会第38年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都新宿区）
- Year and Date
  2016-05-10
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アミロイドーシス変異アポA-I Iowaの脂質膜結合状態の解析2016
- Author(s)
  水口智晴，三河志穂，馬場照彦，島内寿徳，重永章，奥平桂一郎，大高章，斎藤博幸
- Organizer
  膜シンポジウム2016
- Place of Presentation
  関西大学（大阪府吹田市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アポA-I Iowa変異は脂質膜上でのアミロイド形成を促進する2016
- Author(s)
  水口智晴、緒方風夏、三河志穂、馬場照彦、島内寿徳、斎藤博幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 細菌Ⅲ型分泌装置のエフェクター輸送機構解明のための回転-分泌相関の検討2016
- Author(s)
  扇田隆司, 林直樹, 福田昂平, 籾山京子, 小暮健太朗, 後藤直正, 斎藤博幸
- Organizer
  第14回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  ロッジ舞州（大阪府大阪市）
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] G26R変異型アポリポタンパク質A1線維の細胞毒性はリソソーム依存的である2016
- Author(s)
  亀山泰和、西辻和親、奥平桂一郎、小林典裕、斎藤博幸、坂下直実
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] シクロデキストリン架橋型キトサン-pH応答性ペプチド複合体による細胞コレステロール排出促進作用2015
- Author(s)
  武知佑樹, 田中健斗，辻耕平，麻見安雄，井澤浩則，重永章，大高章，川上亘作，斎藤博幸
- Organizer
  日本膜学会第37年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] キネティクスに基づく細胞へのオクタアルギニンの物理的膜透過メカニズム2015
- Author(s)
  武知（原矢）佑樹，安岐健三，通山由美，原野雄一，川上徹，斎藤博幸，岡村恵美子
- Organizer
  日本膜学会第37年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] HDL-apoA-Iの結合構造を特異的に認識する抗apoA-I抗体の開発と相互作用評価2015
- Author(s)
  木村仁，三河志穂，小林典裕，斎藤博幸
- Organizer
  膜シンポジウム2015
- Place of Presentation
  神戸大学（兵庫県）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] AApoAIアミロイドーシスにおけるヘパラン硫酸多硫酸化ドメインの役割2015
- Author(s)
  桑原香織，西辻和親，山下太郎，小林典裕，内村健治，安東由喜雄，斎藤博幸，坂下直実
- Organizer
  第3回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京都）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アポA-I結合タンパク質AIBPの機能解明に向けた研究2015
- Author(s)
  杉原涼、木村仁、奥平桂一郎、斎藤博幸
- Organizer
  日本膜学会第37年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アポEアイソフォームの脂質結合挙動に対する自己会合性の影響2015
- Author(s)
  水口智晴、Phillips, M.C.，Lund-Katz, S，斎藤博幸
- Organizer
  日本膜学会第37年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アポA-Iアミロイド線維形成に与える脂質膜とヘパリンの影響2015
- Author(s)
  三河志穂、水口智晴、辻耕平、重永章、島内寿徳、大高章、斎藤博幸
- Organizer
  日本膜学会第37年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ApoAIアミロイドの毒性に対するヘパラン硫酸糖鎖の影響2015
- Author(s)
  西辻和親，桑原香織，小林典裕，内村健治，坂下直実，斎藤博幸
- Organizer
  日本膜学会第37年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 脂質膜上でのアポA-Iアミロイド形成に及ぼすコレステロールの影響2015
- Author(s)
  緒方風夏、水口智晴、三河志穂、斎藤博幸
- Organizer
  第54回日本薬学会中国四国支部学術大会
- Place of Presentation
  高知市文化プラザ（高知県）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Studies on the functions of apoA-I binding protein, AIBP2015
- Author(s)
  R Sugihara, H Kimura, S Tsuchiya, N Kobayashi, K Okuhira, H Saito
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] HDL産生過程でABCA1が二量体化することの生理的意味の解明2015
- Author(s)
  石神正登，永田紅，永岩耕太，笠井倫志，楠見明弘，長尾耕治郎，斎藤博幸，木村泰久，木岡紀幸，植田和光
- Organizer
  第57回脂質生化学会
- Place of Presentation
  一橋大学一橋講堂（東京都）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ApoA-I アミロイドーシスにおけるオートファジー-リソソーム系の役割2015
- Author(s)
  亀山泰和，西辻和親，小林典裕，斎藤博幸，坂下直実
- Organizer
  第61回日本病理学会秋期特別総会
- Place of Presentation
  東京大学安田講堂（東京都）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 脂質膜環境におけるアポA-Iアミロイド形成機構の解明2015
- Author(s)
  水口智晴、緒方風夏、三河志穂、馬場照彦、島内寿徳、斎藤博幸
- Organizer
  第54回日本薬学会中国四国支部学術大会
- Place of Presentation
  高知市文化プラザ（高知県）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] MicroCal iTC200による細胞膜透過ペプチド－糖鎖間相互作用の熱力学的解析2014
- Author(s)
  武知佑樹, 水口智晴，川上徹，斎藤博幸
- Organizer
  GE Life Sciences Day 2014
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-08-01
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ApoAIアミロイドの毒性に対するヘパラン硫酸糖鎖の影響2014
- Author(s)
  桑原香織，西辻和親，小林典裕，内村健治，坂下直実，斎藤博幸
- Organizer
  第2回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京都千代田区）
- Year and Date
  2014-08-22
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Apolipoprotein A-I周囲環境変化に着目した新規HDL形成測定法の開発2014
- Author(s)
  長尾耕治郎，大村理紗，斎藤博幸
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] フラグメントペプチドを用いたアポA-Iアミロイド線維形成領域の同定2014
- Author(s)
  足立愛美，辻耕平，川島浩之，重永章，長尾耕治郎，赤路健一，大高章，斎藤博幸
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館（熊本県）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] HDL形成におけるapolipoprotein A-IのC末端領域の機能2013
- Author(s)
  長尾耕治郎，端茉美，田中健斗，川上　徹，相本三郎，斎藤博幸
- Organizer
  膜シンポジウム2013
- Place of Presentation
  京都府立医科大学（京都府）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 環境感受性プローブを用いた新規HDL形成評価法の開発2013
- Author(s)
  大村理紗，長尾耕治郎，斎藤博幸
- Organizer
  第52回日本薬学会中国四国支部学術大会
- Place of Presentation
  松山大学（愛媛県）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アミロイドーシス変異アポA-Iの線維形成に及ぼす脂質膜の影響2013
- Author(s)
  水口智晴，足立愛美，川島浩之，長尾耕治郎，赤路健一，斎藤博幸
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学薬学部（東京都）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Interaction of heavy metal ions with artificial tetraether-type phospholipid membranes2013
- Author(s)
  馬場照彦，高木俊之，金森敏幸，岡辰也，斎藤博幸
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都国際会議場（京都府京都市）
- Data Source
  KAKENHI-PROJECT-25670014
[Presentation] 脂質膜環境下でのアポA-Iアミロイド線維形成2013
- Author(s)
  水口智晴，足立愛美，川島浩之，長尾耕治郎，赤路健一，斎藤博幸
- Organizer
  日本膜学会第35年会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アポE含有脂質ナノディスクの腫瘍細胞への集積性評価2013
- Author(s)
  星川梢、辻野奈緒美、田中将史，斎藤博幸，向高弘
- Organizer
  第63回日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学（京都府京田辺市）
- Data Source
  KAKENHI-PROJECT-25670014
[Presentation] HDL形成におけるapoA-IのＣ末端領域の役割2013
- Author(s)
  田中健斗，端茉美，長尾耕治郎， Lund-Katz, S.，Phillips, M.C.，斎藤博幸
- Organizer
  第52回日本薬学会中国四国支部学術大会
- Place of Presentation
  松山大学（愛媛県）
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 安定膜形成性人工リン脂質とアポリポタンパク質A-Iからの膜ディスク形成とその安定性2012
- Author(s)
  馬場照彦, 高木俊之, 金森敏幸, 岡辰也, 斎藤博幸
- Organizer
  平成23年度第11回産業技術総合研究所・産業技術連携推進会議ライフサイエンス部会・バイオナノテクノロジー分科会合同研究発表会
- Place of Presentation
  茨城県・産業技術総合研究所つくばセンター共用講堂
- Year and Date
  2012-01-31
- Data Source
  KAKENHI-PROJECT-22550170
[Presentation] Physicochemical Mechanism for the Enhanced Ability of Lipid Membrane Penetration of Polyarginine2012
- Author(s)
  Takechi, Y., Yoshii, H., Tanaka, M., Kawakami, T., Aimoto, S., Okamura, E., Saito, H
- Organizer
  International Association of Colloid and Interface Scientists 2012
- Place of Presentation
  仙台国際センター,宮城県
- Data Source
  KAKENHI-PROJECT-22590046
[Presentation] 分枝鎖人工リン脂質とアポリポタンパク質A-Iからの膜ディスク形成2012
- Author(s)
  馬場照彦, 高木俊之, 金森敏幸, 半田大祐, 岡辰也, 斎藤博幸
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  神奈川県・慶應義塾大学日吉キャンパス
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22550170
[Presentation] 安定膜形成性リン脂質と脂質親和性タンパク質との自己組織化構造2012
- Author(s)
  馬場照彦, 高木俊之, 金森敏幸, 岡辰也, 斎藤博幸
- Organizer
  平成23年度産業技術連携推進会議ナノテクノロジー・材料部会/製造プロセス部会合同研究発表会
- Place of Presentation
  茨城県・産業技術総合研究所つくばセンター共用講堂
- Year and Date
  2012-02-02
- Data Source
  KAKENHI-PROJECT-22550170
[Presentation] 部分フッ素化リン脂質と脂質親和性タンパク質からの膜ディスク形成2012
- Author(s)
  馬場照彦、高木俊之、金森敏幸、岡辰也、斎藤博幸
- Organizer
  日本膜学会第34年会
- Place of Presentation
  早稲田大学西早稲田キャンパス63号館（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-22550170
[Presentation] Interactions of apoA-I with HDL particles2012
- Author(s)
  Lund-Katz, S., Nguyen, D., Dhanasekaran, P., Nickel, M., Hata, M., Saito, H., Phillips, M. C
- Organizer
  XVI International Symposium on Atherosclerosis HDL Satellite Meeting
- Place of Presentation
  Hilton Cairns, Cairns, Australia
- Data Source
  KAKENHI-PROJECT-22590046
[Presentation] テトラエーテル型人工リン脂質とアポリポタンパク質からの膜ディスク形成2012
- Author(s)
  馬場照彦、高木俊之、金森敏幸、半田大祐、岡辰也、斎藤博幸
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学東山キャンパス（名古屋市）
- Data Source
  KAKENHI-PROJECT-22550170
[Presentation] 安定膜形成性人工リン脂質と脂質親和性タンパク質との複合体形成2011
- Author(s)
  馬場照彦, 高木俊之, 金森敏幸, 岡辰也, 斎藤博幸
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  茨城県・つくば国際会議場
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-22550170
[Presentation] テトテエーテル型リン脂質類縁体の膜特性と脂質親和性タンパク質との複合体形成2011
- Author(s)
  馬場照彦, 高木俊之, 金森敏幸, 岡辰也, 斎藤博幸
- Organizer
  日本膜学会第33年会
- Place of Presentation
  東京都・産業技術総合研究所臨海副都心センター別館
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-22550170
[Presentation] Amide hydrogen-deuterium exchange as a tool to probe the effects of point-mutations on apolipoprotein A-I structure-function2011
- Author(s)
  Chetty, P. S., Takase, H., Saito, H., Lund-Katz, S., Mayne, L., Englander, W., Phillips, M. C
- Organizer
  Arteriosclerosis, Thrombosis and Vascular Biology 2011
- Place of Presentation
  Hilton Chicago, Chicago, USA
- Data Source
  KAKENHI-PROJECT-22590046
[Presentation] 安定膜形成性人工リン脂質とアポリポタンパク質A-Iからの膜ディスク形成とその安定性2011
- Author(s)
  馬場照彦, 高木俊之, 金森敏幸, 岡辰也, 斎藤博幸
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  日本化学会第91春季年会(2011)講演予稿集
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-22550170
[Presentation] Interactions of apolipoprotein A-I with spherical HDL particles2010
- Author(s)
  Lund-Katz, S., Nguyen, D., Dhanasekaran, P., Kono, M., Nickel, M., Saito, H., Phillips, M. C
- Organizer
  6thIAS-sponsored Workshop on HDL
- Place of Presentation
  Westin Whistler, Whistler, Canada
- Data Source
  KAKENHI-PROJECT-22590046
[Presentation] Effect of amino acid residues on membrane curvature sensing of amphipathic helix in human apolipoprotein A-I2010
- Author(s)
  Tanaka, M., Takamura, Y., Kawakami, T., Aimoto, S., Saito, H
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  京都国際会議場,京都府
- Data Source
  KAKENHI-PROJECT-22590046
[Presentation] C末端ヘリックス変異体apoA-I Nichinanの構造と脂質結合性の評価2009
- Author(s)
  河野百恵, 田中将史, Lund-Katz, S., Phillips, M. C., 斎藤博幸
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] 環境感受性蛍光プローブ標識によるアポA-IのC末端ヘリックス領域の構造評価2009
- Author(s)
  小山真央, 田中将史, Lund-Katz, S., Phillips, M.C., 斎藤博幸
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] アポE3N末ドメインの構造と脂質搬出機能に及ぼすダイマー化の影響2009
- Author(s)
  高木千佳, 源川博久, Lund-Katz, S., Phillips, M. C., 道川誠, 斎藤博幸
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] ApoA-I Nichinan脂質搬出機能部位ペプチドの脂質膜との相互作用2009
- Author(s)
  田中俊充, 岩田真季, 河野百恵, 田中将史, Lund-Katz, S.,斎藤博幸
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] C末端フラグメントペプチドによるapoA-I Nichinan変異体の構造と脂質結合性の評価2008
- Author(s)
  田中俊充, 久留島祐未, 田中将史, 杉浦眞喜子, Lund-Katz, S., 斎藤博幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] アポA-I-脂質複合ナノ粒子の創製とその物性・機能評価2008
- Author(s)
  田中将史, 澤井治子, 坂倉広大, 北川英俊, 奥村優介, 斎藤博幸
- Organizer
  膜シンポジウム2008
- Place of Presentation
  豊中
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] 低HDL血症apoA-I変異体の脂質結合部位ペプチドの構造と機能評価2008
- Author(s)
  田中俊充, 中寺麻理子, 岩田真季, 田中将史, 杉浦眞喜子, Lund-Katz, S., 斎藤博幸
- Organizer
  第58回日本薬学会近畿支部大会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] アポリポ蛋白質EのN末、C末ドメインのグリコサミノグリカン結合性への寄2008
- Author(s)
  出口敬子, 山内悠子, 中野実, 半田哲郎, 斎藤博幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] ヒト/マウスキメラ型アポA-Iを用いたN末-C末ドメイン間相互作用の解析2008
- Author(s)
  小山真央, 木澤愛実, 田中将史, Lund-Katz, S., Phillips, M.C., 斎藤博幸
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-08-07
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] 急性期タンパク質血清アミロイドA(SAA)の脂質結合部位の特定2008
- Author(s)
  大田慎也, 田中将史, 川上徹, 相本三郎, 斎藤博幸
- Organizer
  第58回日本薬学会近畿支部大会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] フラグメントペプチドを用いた血清アミロイドA(SAA)各領域の脂質結合性の比較2008
- Author(s)
  大田慎也, 田中将史, 川上徹, 相本三郎, 斎藤博幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] C末端単一トリプトファン変異体を用いたアポE-脂質複合体の構造評価2008
- Author(s)
  奥村優介, 高木千佳, 田中将史, Lund-Katz, S., 斎藤博幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] 低HDL血症変異体apoA-I Milano(R173C)の水溶液構造と脂質結合性2008
- Author(s)
  河野百恵, 坂倉広大, 田中将史, Lund-Katz, S., Phillips, M.C., 斎藤博幸
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-08-07
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] アポA-Iの脂質結合性に及ぼすN末及びC末ドメイン構造の影響2008
- Author(s)
  斎藤博幸, 小山真央, 田中将史, Lund-Katz, S., Phillips, M. C.
- Organizer
  日本膜学会第30年会
- Place of Presentation
  東京
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] 単一トリプトファン変異体を用いたアポEアイソフォームC末ドメインの構造評価2008
- Author(s)
  高木千佳, 岡田愛弓, 奥村優介, 田中将史, Lund-Katz, S., Phillips, M.C., 斎藤博幸
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-08-07
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] ヒトSerum Amyloid AのN末端領域は脂質結合に重要な役割を果たす2008
- Author(s)
  大田慎也, 田中将史, 川上徹, 相本三郎, 斎藤博幸
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] マウスアポA-Iにおけるドメイン構造と脂質結合性2007
- Author(s)
  斎藤博幸, 小山真央, 田中将史, Lund-Katz, S., Phillips, M.C.
- Organizer
  第29回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-11-26
- Data Source
  KAKENHI-PROJECT-19590048
[Presentation] 環境感受性蛍光プローブ標識アポA-Iを利用した新規HDL形成検出法の開発
- Author(s)
  大村理紗，長尾耕治郎，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 部位特異的蛍光標識によるアポEアイソフォームの脂質結合挙動の解析
- Author(s)
  水口智晴，端茉美，Phillips, M.C.，Lund-Katz, S.，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] オクタアルギニンの物理的膜透過に関するリアルタイムin cell NMR研究
- Author(s)
  武知佑樹, 安岐健三，通山由美，川上徹，斎藤博幸，岡村恵美子
- Organizer
  日本膜学会第36年会
- Place of Presentation
  早稲田大学（東京都新宿区）
- Year and Date
  2014-05-12 – 2014-05-13
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] アミロイドーシスの病態解明を目指したApoA-Iモノクローナル抗体の作製
- Author(s)
  堀江有紀，土屋沙織，大山浩之，小林典裕，斎藤博幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Real Time in-Cell 19F NMR Spectroscopy on the Cell Membrane Permeation of Octaarginine.
- Author(s)
  Takechi, Y., Aki, K., Tohyama, Y., Kawakami, T., Saito, H., Okamura, E.
- Organizer
  International Conference on Magnetic Resonance for Biological Systems 2014
- Place of Presentation
  Dallas (Texas, USA)
- Year and Date
  2014-08-24 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] DESIGN OF NANODISC SCAFFOLD PEPTIDE (NSP)
- Author(s)
  假屋園大和, 新村航，辻耕平，重永章，大高章，斎藤博幸
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学蔵本キャンパス（徳島県徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25670014
[Presentation] ApoA-I欠損変異体を用いたナノディスクの作製及び物性評価
- Author(s)
  新村航，假屋園大和，奥平桂一郎，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] HDLアポA-Iの自発的交換反応に関する速度論的・熱力学的解析
- Author(s)
  半田大祐，岡辰也，武知佑樹，奥平桂一郎，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学蔵本キャンパス（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25670014
[Presentation] バイオレイヤー干渉法を用いた人工HDL粒子と抗apoA-I抗体との相互作用評価
- Author(s)
  木村仁，原矢佑樹，小林典裕，斎藤博幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] バイオレイヤー干渉法を用いた人工HDL粒子と抗apoA-I抗体との相互作用評価
- Author(s)
  木村仁，原矢佑樹，小林典裕，斎藤博幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25670014
[Presentation] アルギニン変異apoA-Iフラグメントのアミロイド線維形成性
- Author(s)
  三河志穂，水口智晴，辻耕平，馬場照彦，重永章，大高章，斎藤博幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] Arginine- Glycosaminoglycan Interaction Regulates Penetration Efficiency of Arginine-rich Cell-penetrating Peptides in Biological Membrane.
- Author(s)
  Takechi Y., Yanagisawa Y., Nishitsuji K., Uchimura K., Kawakami T., Kawakami K., Okuhira K., Saito H.
- Organizer
  Biophysical Society 59th Annual Meeting
- Place of Presentation
  Baltimore (Maryland, USA)
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ApoAIアミロイドの毒性に対するヘパラン硫酸糖鎖の影響
- Author(s)
  桑原香織，西辻和親，小林典裕，内村健治，坂下直実，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] In cell NMRによるオクタアルギニンペプチドの細胞内輸送のリアルタイム計測と速度論
- Author(s)
  武知佑樹, 安岐健三，通山由美，川上徹，斎藤博幸，岡村恵美子
- Organizer
  第65回コロイドおよび界面化学討論会
- Place of Presentation
  東京理科大学（東京都新宿区）
- Year and Date
  2014-09-03 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] DESIGN OF NANODISC SCAFFOLD PEPTIDE (NSP)
- Author(s)
  假屋園大和, 新村航，辻耕平，重永章，大高章，斎藤博幸
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 環境感受性蛍光プローブ標識アポA-Iを利用した新規HDL形成検出法の開発
- Author(s)
  大村理紗，長尾耕治郎，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学蔵本キャンパス（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25670014
[Presentation] アルギニンペプチドの細胞膜透過性に与えるグリコサミノグリカン糖鎖相互作用の影響
- Author(s)
  武知佑樹, 柳澤悠登，西辻和親，川上徹，奥平桂一郎，斎藤博幸
- Organizer
  膜シンポジウム2014
- Place of Presentation
  神戸大学（兵庫県神戸市）
- Year and Date
  2014-11-26 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] HDLアポA-Iの自発的交換反応に関する速度論的・熱力学的解析
- Author(s)
  半田大祐，岡辰也，武知佑樹，奥平桂一郎，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ROLE OF GAG INTERCTION IN BIOLOGICAL MEMBRANE PENETRATION OF ARGININE-RICH CELL-PENETRATING PEPTIDE
- Author(s)
  武知佑樹, 柳澤悠登，西辻和親，川上徹，奥平桂一郎，斎藤博幸
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ApoA-I欠損変異体を用いたナノディスクの作製及び物性評価
- Author(s)
  新村航，假屋園大和，奥平桂一郎，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学蔵本キャンパス（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25670014
[Presentation] トリプトファン変異導入によるアポEアイソフォームの二ドメイン構造の比較評価
- Author(s)
  水口智晴，端茉美，Phillips, M.C.，Lund-Katz, S，斎藤博幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] ヒトアポA-I結合タンパク質AIBPの大腸菌発現系の構築と細胞内局在
- Author(s)
  杉原涼，長尾耕治郎，奥平桂一郎，斎藤博幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] カチオン性ペプチドの細胞膜透過促進機構～アルギニンペプチドのグリコサミノグリカン糖鎖への特異的結合によるα-ヘリックス構造形成～
- Author(s)
  武知佑樹, 柳澤悠登，西辻和親，川上徹，川上亘作，奥平桂一郎，斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学（徳島県徳島市）
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25293006

1. TANAKA Masafumi (40411904)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
2. NAGAO Kohjiro (40587325)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. BABA Teruhiko (40357794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. KOBAYASHI Norihiro (90205477)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
5. TAKAGI Toshiyuki (10248065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. KIYONO Masako (30239842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. AKAJI Kenichi (60142296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. OTAKA Akira (20201973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OKAMURA Emiko (00160705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. KITAGAWA Shuji (00108911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MICHIKAWA Makoto (40270912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KAWAKAMI Toru (70273711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 笠原二郎 (10295131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 坂下直実 (90284752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. HASEGAWA Koki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. OYAMA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. UCHIMURA Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. DEMIZU YOSUKE

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. HARANO Yuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 大高章

# of Collaborated Projects: 0 results

# of Collaborated Products: 18 results
21. 植田和光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 伊藤隆明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 西辻和親

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
24. 安東由喜雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 山下太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 森田いずみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 内藤幹彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 服部隆行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 芳賀永

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 有賀克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 池崎みどり

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 井原義人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 岩橋尚幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saito Hiroyuki 斎藤 博幸

斎藤 博幸 サイトウ ヒロユキ

SAITO Hiroyuki 斎藤 博幸

Research Projects

Research Products

Co-Researchers

タンパク質の自己凝集・アミロイド線維化を促進する体内分子ネットワークの解明と制御Principal Investigator

Principal Investigator

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Review Section

Research Institution

Mechanisms of aggregation and fibril formation of amyloidogenic proteins with amyloid cofactorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physicochemical mechanisms of amyloid fibril formation by amyloidogenic apolipoproteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physicochemical mechanism on formation and metabolism of HDL particles by apolipoproteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of HDL-like lipid membrane discs for reconstitution of membrane proteinsPrincipal Investigator

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Basic research on handling of heavy-metal ion transporter protein as a sensor element

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Structural basis of dysfunctional apolipoprotein-induced dyslipidemiaPrincipal Investigator

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Role of Apolipoprotein E Structure in Disorders of Lipid Metabolism in BrainPrincipal Investigator

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アポリポタンパク質Eの脂質及び細胞受容体結合の分子機構Principal Investigator

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モデルペプチドを用いたアポリポタンパク質脂質膜結合機構に関する研究Principal Investigator

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血漿アポリポ蛋白質の結合選択性を利用した脂質エマルションの体内代謝の制御Principal Investigator

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[Book] Lipids in Protein Misfolding2015

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[Book] 製剤への物理化学第2版2012

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Saito Hiroyuki 斎藤博幸

斎藤博幸サイトウヒロユキ

SAITO Hiroyuki 斎藤博幸

[Book] 製剤への物理化学第2版2012