MIYASAKA Takehiro 宮坂武寛

… Alternative Names

宮坂武寛ミヤサカタケヒロ

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Researcher Number	60308195
Other IDs
External Links
Affiliation (Current)	2025: 湘南工科大学, 工学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 湘南工科大学, 工学部, 教授 2012: 姫路獨協大学, 公私立大学の部局等, 教授 2006 – 2011: 姫路獨協大学, 医療保健学部, 教授 2010: 姫路獨協大学, 保健医療学部, 教授 2006 – 2007: 姫路獨協大学, 健康保健学部, 教授 … More 2005: 岡山大学, 大学院医歯薬学総合研究科, 助手 2004 – 2005: 岡山大学, 医学部, 助手 2003 – 2005: 岡山大学, 大学院・医歯学総合研究科・医学部, 助手 2003 – 2004: Okayama University Medical School, Dept.of Cardiovascular Physiology, Research Associate, 大学院・医歯学総合研究科, 助手 2003: 岡山大学, 大学院・医歯学総合研究所, 助手 2000 – 2002: 川崎医科大学, 医学部, 助手 2001: 川崎医科大学, 生理学, 助手 Less
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Biomedical engineering/Biological material science Except Principal Investigator Biomedical engineering/Biological material science / Basic Section 55060:Emergency medicine-related / Ophthalmology / Circulatory organs internal medicine / Biomedical engineering/Biological material science / 生物・生体工学
Keywords	Principal Investigator 血液透析 / 一酸化窒素 / 活性酸素 / 酸化ストレス / 化学工学 / 人工臓器 / 虚血再灌流モデル / ビタミンEコーティング / 血液透析膜 / リアルタイムモニタリング … More / スーパーオキサイドセンサ / バイオセンサ / スーパーオキサイド / 透析液清浄度 / インラインモニタリングシステム / 透析液 / エンドトキシン … More Except Principal Investigator SPring-8 / Frank Starling Law / Contraction / Crossbridge / X-ray Diffraction / X線回折 / Myofilament Lattice / クロスブリッジ / アクチン / Transmural Heterogeneity / 筋線維 / 完全液体換気 / ARDS / 液体呼吸 / ファインバブル / マイクロ・ナノバブル / 肺洗浄 / 急性呼吸窮迫症候群 / Ca Transient / Hypoxia / ミオシン / 心臓 / Heart / superoxide dismutase (SOD) / superoxide / 心機能 / 心不全 / カルシウム / 心肥大 / 冠循環 / スーパーオキサイド / 心筋線維六角格子 / 再生医療 / クロスブリッジ動態 / 六角格子 / 心筋細胞 / Total Liquid Ventilation / LPS / 敗血症 / 急性呼吸窮迫性症候群 / 完全液体呼吸 / ラット / 左心室自由壁 / Heart Rate / srcomere / laser diffraction / x-ray diffraction / crossbridge / myosin head / actin / cardiac muscle / synchrotron radiation x-ray / レーザ回折 / サルコメア / レーザ解析 / X線回折像 / ミオシンヘッド / 心筋 / 放射光 / X線回析 / ミオシン格子間隔 / マクロモレキュール / 心筋線維配向 / X線回折像解析 / アクチン・ミオシン / 筋節長 / Miofilament Lattice / endothelial function / catheter / sensor / nitric oxide (NO) / in vivo計測 / センサー / 冠状静脈洞 / 酸化窒素(NO) / 血管内皮機能 / カテーテル / センサ / 一酸化窒素(NO) / フィジオーム / 機械受容 / 酸素環境 / 心筋分裂 / 心臓超音波 / 可変弾性モデル / Na^+-Ca^<2+>交換体 / 拡張性 / 収縮性 / 心室形熊 / Caトランスポータ / 拡張能 / 収縮能 / マイクロチップ / アロステリック効果 / 酸素分圧 / 周産期 / 胎児循環 / 胎児ヘモグロビン / 血管新生 / 酸素親和度 / ヘモグロビン / 未熟児網膜症 / ナトリウムカルシウム交換体 / クリスタリン / 水晶体 / 高血圧 / 酸化ストレス / NO / 心肥大・発達 / 収縮蛋白 / 可逆的不死化 / 心筋細胞培養 / 発達 / 筋節構造 / 六角格子構造 / 細胞不死化 / 心筋組織 / 細胞移植 / 培養心筋 / マクロモレキュル / アクチン・ミオシン分子動態 / ナノ機能評価 / 心筋肥大 / 三次元構築 Less

Evaluation of therapeutic effects of short-time liquid ventilation and novel drug delivery systems in a rat ARDS model.
- Principal Investigator
  
  Harii Norikazu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  University of Yamanashi
Total liquid ventilation with oxygen micro/nano bubble dispersion ameliorates lipopolysaccharide-induced acute respiratory distress syndrome in rats.
- Principal Investigator
  
  HARII Norikazu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  University of Yamanashi
Physiomic analyses of cardiac hypertrophy and ventricular geometry of in cardiac regulation
- Principal Investigator
  
  MOHRI Satoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki Medical School
Coronary Circulation-Cardiac Mechanics Coupling
- Principal Investigator
  
  MOHRI Satoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki Medical School
未熟児網膜症におけるヘモグロビン変換の関与
- Principal Investigator
  
  毛利聡
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kawasaki Medical School
  Okayama University
血液透析時の血圧低下に対する一酸化窒素と酸化ストレスの関与Principal Investigator
- Principal Investigator
  
  宮坂武寛
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Himeji Dokkyo University
水晶体発育期のクリスタリン構造調節因子:SPring-8X線回折による統合的解析
- Principal Investigator
  
  毛利聡
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Okayama University
Pathophysiological analysis of myocardial dysfunction by observing nanometer ordernanometer-order dynamics of actin-myosin, interaction
- Principal Investigator
  
  SHIMIZU Juichiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nara Medical University
高血圧症の発症および進展におけるスーパーオキサイドと一酸化窒素(NO)の役割
- Principal Investigator
  
  越智和典
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki Medical School
生体内連続計測用スーパーオキサイドセンサの開発Principal Investigator
- Principal Investigator
  
  宮坂武寛
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Okayama University
医工学的再構築心筋組織の作成およびナノオーダー機能評価
- Principal Investigator
  
  KAJIYA Fumihiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Okayama University
可逆性完全不死化心筋細胞株の樹立およびナノオーダー機能評価
- Principal Investigator
  
  清水壽一郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Okayama University
Integrated analysis of three-dimensional molecular dynamics of actin and myosin, and macro-dynamics of cardiac muscle and left ventricle
- Principal Investigator
  
  TSUJIOKA Katsuhiko
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki Medical School
Analyses of transmural difference of myocardial crossbridge dynamics using SPring-8 synchrotron facility
- Principal Investigator
  
  SHIMIZU Jyuichiro, 荒木淳一
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  OKAYAMA UNIVERSITY
Development of an in vivo real-time measurement system of nitric oxide and superoxide and their clinical applications
- Principal Investigator
  
  MOCHIZUKI Seiichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  Kawasaki College of Allied Health Professions
透析液中エンドトキシンインラインモニタリングシステムの開発Principal Investigator
- Principal Investigator
  
  宮坂武寛
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki Medical School

All 2023 2022 2021 2020 2019 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Do Ultrafine Bubbles Work as Oxygen Carriers?2023
- Author(s)
  Kakiuchi Kenta、Kozuka Tomoki、Mase Nobuyuki、Miyasaka Takehiro、Harii Norikazu、Takeoka Shinji
- Journal Title
  
  Langmuir
  
  Volume: 39 Issue: 4 Pages: 1354-1363
- DOI
  10.1021/acs.langmuir.2c01209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18189, KAKENHI-PROJECT-21H01974, KAKENHI-PROJECT-21K09013
[Journal Article] Development of quantitative and concise measurement method of oxygen in fine bubble dispersion2022
- Author(s)
  Kakiuchi Kenta、Miyasaka Takehiro、Harii Norikazu、Takeoka Shinji
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 2 Pages: 1-13
- DOI
  10.1371/journal.pone.0264083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22506, KAKENHI-PROJECT-21K09013
[Journal Article] Total alveolar lavage with oxygen fine bubble dispersion directly improves lipopolysaccharide-induced acute respiratory distress syndrome of rats2020
- Author(s)
  Kakiuchi Kenta、Miyasaka Takehiro、Takeoka Shinji、Matsuda Kenichi、Harii Norikazu
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-020-73768-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22506, KAKENHI-PROJECT-18K08913
[Journal Article] Heart slice NMR2007
- Author(s)
  Uetani T, Yamashita D, Shimizu J, Misawa H, Tatematsu Y, Hamaguchi Y, Miyasaka T, Katanosaka Y, Kato T,
- Journal Title
  
  Am J physiol Heart Circ Physiol 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390231
[Journal Article] Measurements of CO_2, lactic acid and sodium bicarbonate secreted by cultured cells using a flow-through type pH/CO_2 sensor system based on ISFET.2006
- Author(s)
  Mohri S, Shimizu J, Goda N, Miyasaka T, Fujita A, Nakamura M, Kajiya F
- Journal Title
  
  Sensors and Actuators B : Chemical 115(1)
  
  Pages: 519-525
- Data Source
  KAKENHI-PROJECT-17659548
[Journal Article] Iris movement mediates vascular apoptosis during rat pupillary membrane regression.2006
- Author(s)
  Monzane Y, Mohri S, Kosaka J, Tone S, Kiyooka T, Miyasaka T, Shimizu J, Ogasawara Y, Shiraga F, Minatogawa Y, Sasaki J, Ohtsuki H, Kajiya F.
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol. 290・3
- Data Source
  KAKENHI-PROJECT-17390231
[Journal Article] Changes in lattice spacing during afterloaded contraction in rat papillary muscle.2005
- Author(s)
  Hiroshi Okuyama, Hiroko Toyota, Naoto Yagi, Juichiro Shimizu, Satoshi Mohri, Takehiro Miyasaka, Yuhki Morizane, Katsuhiko Tsujioka, Fumihiko Kajiya
- Journal Title
  
  SPring-8 User Experiment Report No.14(2004B)
  
  Pages: 228-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300175
[Journal Article] Changes in lattice spacing during afterloaded contraction in rat papillary muscle.2005
- Author(s)
  Hiroshi Okuyama, Toyota Hiroko, Naoto Yagi, Juichiro Shimizu, Satoshi Mohri, Takehiro Miyasaka, Yuhki Morizane, Katsuhiko Tsujioka, Fumihiko Kajiya
- Journal Title
  
  Spring-8 User Experiment Report No.14(2004B)
  
  Pages: 228-228
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300175
[Journal Article] Regression of capillary network in atrophied soleus muscle induced by hindlimb unweighting.2005
- Author(s)
  Fujino H, Kohzuki H, Takeda I, Kiyooka T, Miyasaka T, Mohri S, Shimizu J, Kajiya F.
- Journal Title
  
  J Appl Physiol. 98・4
  
  Pages: 1407-1413
- Data Source
  KAKENHI-PROJECT-17390231
[Presentation] 酸酸ファインバブル分散水中の酸素含量測定方法の確立および酸素運搬体としての物性評価2023
- Author(s)
  垣内健太、小塚智貴、間瀬暢之、宮坂武寛、針井則一、武岡真司
- Organizer
  日本化学会第103春季年会，東京，2023.3
- Data Source
  KAKENHI-PROJECT-21K09013
[Presentation] 酸素ファインバブルは酸素運搬体として機能するのか？2023
- Author(s)
  垣内健太、小塚智貴、間瀬暢之、宮坂武寛、針井則一、武岡真司
- Organizer
  化学工学会第88年会，東京，2023.3
- Data Source
  KAKENHI-PROJECT-21K09013
[Presentation] 酸素ファインバブルは酸素運搬体として機能するのか？2023
- Author(s)
  垣内健太、小塚智貴、間瀬暢之、宮坂武寛、針井則一、武岡真司
- Organizer
  化学工学会第88年会，東京，2023.3
- Data Source
  KAKENHI-PROJECT-21K09013
[Presentation] 酸素ファインバブル分散水中の酸素含量測定方法の確立および酸素運搬体としての物性評価2023
- Author(s)
  垣内健太、小塚智貴、間瀬暢之、宮坂武寛、針井則一、武岡真司
- Organizer
  日本化学会第 103春季年会，東京，2023.3（国内、ポスター）
- Data Source
  KAKENHI-PROJECT-21K09013
[Presentation] 酸素ファインバブルの酸素運搬体としての物性評価2022
- Author(s)
  垣内健太、小塚智貴、間瀬暢之、宮坂武寛、針井則一、武岡真司
- Organizer
  第29回日本血液代替物学会年次大会，東京，2022.12
- Data Source
  KAKENHI-PROJECT-21K09013
[Presentation] 酸素ファインバブル分散液を用いた完全液体換気技術の開発と肺洗浄治療効果2022
- Author(s)
  垣内健太，針井則一、宮坂武寛、松田兼一、武岡真司
- Organizer
  医工学治療学会第38回学術大会，愛媛，2022.5
- Data Source
  KAKENHI-PROJECT-21K09013
[Presentation] Fundamental property of fine bubble dispersion as an oxygen carrier2021
- Author(s)
  Kenta Kakiuchi, Tomoki Kozuka, Nobuyuki Mase, Takehiro Miyasaka, Norikazu Harii, Shinji Takeoka
- Organizer
  The 8th Asia biomaterials Federation, Aichi, 2021.11.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09013
[Presentation] 酸素ファインバブル分散液を用いた完全液体換気技術の開発2020
- Author(s)
  垣内健太，針井則一，宮坂武寛，武岡真司
- Organizer
  第24回酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] 酸素マイクロ・ナノバブル分散酸素富化液を用いた完全液体換気の確立2019
- Author(s)
  垣内健太，松田兼一，針井則一，宮坂武寛，武岡真司
- Organizer
  第2回　稲門医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] Total liquid ventilation with oxygen fine bubbles for acute lung injury,2019
- Author(s)
  Kenta Kakiuchi, Norikazu Harii, Takehiro Miyasaka, Shinji Takeoka, Kenichi Matsuda
- Organizer
  The 17th International Symposium on Blood Substitutes and Oxygen Therapeutics, Nara, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] Total Liquid Ventilation with Oxygen Fine Bubble Dispersion Prevents from Acute Lung Injury in Rats2019
- Author(s)
  Kenta Kakiuchi, Norikazu Harii, Takehiro Miyasaka, Shinji Takeoka, Kenichi Matsuda
- Organizer
  The 8th Meeting of the International Federation for Artificial Organs, Osaka, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] TOTAL LIQUID VENTILATION WITH OXYGEN MICRO/NANO BUBBLE DISPERSED SALINE PREVENTS FROM LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY IN RATS2019
- Author(s)
  Kenta Kakiuchi, Shinji Takeoka, Norikazu Harii, Takehiro Miyasaka, Kenichi Matsuda
- Organizer
  The 46th European Society for Artificial Organs, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08913
[Presentation] Increasing preload attenuates crossbridge formation under hypoxia.2008
- Author(s)
  Shimizu J, Yagi N, Miyasaka T, Sakata S, Nakajima-Takenaka C, Misawa H, Takaki M
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-17390231
[Presentation] Increasing preload attenuates crossbridge formation under hypoxia2008
- Author(s)
  Juichiro Shimizu, Yamato Tamura, Takehiro Miyasaka, Daisuke Takeshita, Miako Takaki,
- Organizer
  第72回日本循環器学会
- Place of Presentation
  福岡
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-17390231

1. MOHRI Satoshi (00294413)

# of Collaborated Projects: 8 results

# of Collaborated Products: 3 results
2. SHIMIZU Jyuichiro (80294403)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
3. NAKAMURA Kazufumi (10335630)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. KAJIYA Fumihiko (70029114)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
5. YAGI Naoto (80133940)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
6. KATAOKA Noriyuki (20250681)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. TSUJIOKA Katsuhiko (30163801)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. HASHIMOTO Ken (80341080)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. NARUSE Keiji (40252233)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. KATANOSAKA Yuki (60432639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. HARII Norikazu (80377522)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
12. 武岡真司 (20222094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 森口武史 (60422680)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 菅原久徳 (70746776)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 高三野淳一 (70769281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. IRIBE Genntarou (90284885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. UJIHARA Yoshihiro (80610021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MOCHIZUKI Seiichi (60259596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HIRAMATSU Osamu (50208849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. GOTO Masami (50148699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YOSHIDA Kiyoshi (60322583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. OKUYAMA Hiroshi (30133333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. TAKAKI Miyako (00033358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. 小林直哉 (10325102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 越智和典 (50069077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 遠藤恒介 (00350463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 酒井清孝 (00063727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 大月洋 (70093672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 森実祐基 (50432646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 荒木淳一 (80271055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 松田兼一 (60282480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
32. 垣内健太 (30875422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
33. 後藤順子 (60530102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 土田英俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results

MIYASAKA Takehiro 宮坂 武寛

宮坂 武寛 ミヤサカ タケヒロ

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血液透析時の血圧低下に対する一酸化窒素と酸化ストレスの関与Principal Investigator

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生体内連続計測用スーパーオキサイドセンサの開発Principal Investigator

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MIYASAKA Takehiro 宮坂武寛

宮坂武寛ミヤサカタケヒロ