Katsuyama Masato 勝山真人

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KATSUYAMA Masato 勝山真人

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Researcher Number	60315934
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help	2024: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2013 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2010: 京都府立医科大学, 大学院・医学研究科, 准教授 2009 – 2010: Kyoto Prefectural University of Medicine, 医学研究科, 准教授 2006 – 2008: 京都府立医科大学, 医学研究科, 講師 2003 – 2005: 京都府立医科大学, 医学研究科, 助手 2001 – 2002: 京都府立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General pharmacology / Basic Section 48030:Pharmacology-related / Applied pharmacology / General pharmacology Except Principal Investigator Urology / Applied pharmacology / Urology / General pharmacology
Keywords	Principal Investigator NADPHオキシダーゼ / 活性酸素 / 活性酸素種 / 組織線維化 / 血管平滑筋細胞 / プロスタグランジンF_<2α> / プロスタグランジンF2alpha / NOX1 / 酸化ストレス / 銅 … More / 細胞死 / 薬害スモン / キノホルム / 薬理学 / 線維化 / Sp3 / クリオキノール / NOX / アレルギー / マスト細胞 / 転写調節 / 大腸上皮細胞 / ミトコンドリア / PI3キナーゼ / ERK / EGF受容体 / ATF-1 / 血管平滑筋 … More Except Principal Investigator IGFBP-3 / IGF-I / IGF-1 / 糖尿病 / erectile dysfunction / diabetes mellitus / penis / 陰茎海綿体平滑筋 / ラット / 勃起障害 / transgenic mouse / ischemia-reperfusion injury / heart / aldose reductase / 虚血・再灌流障害 / 遺伝子改変マウス / 虚血・再還流障害 / 心臓 / アルドース還元酵素 / Erectile Dysfunction (ED) / IGFBP-1 / 勃起障害(ED) / 薬理学 / シグナル伝達 / 循環器・高血圧 Less

A study on molecular mechanisms of quinoform-induced cell death dependent on copper and oxidative stressPrincipal Investigator
- Principal Investigator
  
  勝山真人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Study on mechanisms of exacerbation of tissue fibrogenesis by NOX4-derived reactive oxygen speciesPrincipal Investigator
- Principal Investigator
  
  Katsuyama Masato
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Clarification of new oxidative signaling involved in tissue fibrogenesis and its application to therapeutic strategyPrincipal Investigator
- Principal Investigator
  
  Katsuyama Masato
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
A study on signaling pathways associated with NOX4/NADPH oxidase for the development of new antifibrotic drugsPrincipal Investigator
- Principal Investigator
  
  Katsuyama Masato
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
Study on the molecular basis of the exertion of adverse effects of drugs mediated by regulation of NADPH oxidase activitiesPrincipal Investigator
- Principal Investigator
  
  KATSUYAMA Masato
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases
- Principal Investigator
  
  YABE Chihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
A study on the involvement of NADPH oxidase in allergic diseasesPrincipal Investigator
- Principal Investigator
  
  KATSUYAMA Masato
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
血管平滑筋に発現する種特異的な活性酸素産生酵素の解析Principal Investigator
- Principal Investigator
  
  勝山真人
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
Paradoxical roles of the aldehyde-metabolizing enzyme, aldose reductase in cardioprotection
- Principal Investigator
  
  YABE Chihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
Clarification of the sexual dysfunction by diabetes
- Principal Investigator
  
  SHO Jintetsu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kyoto Prefectural University of Medicine
プロスタノイドによる血管平滑筋NADPHオキシダーゼの活性化機構の解明Principal Investigator
- Principal Investigator
  
  勝山真人
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
Effects of insulin - like growth factor binding protein-3 (IGFBP-3) on diabetes - induced erectile dysfunction (ED)
- Principal Investigator
  
  SOU Jintetsu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2022 2019 2015 2014 2011 2010 2009 2008 2006 2005 2004

All Journal Article Presentation

[Journal Article] A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS-activated cancer cells.2019
- Author(s)
  Mori K, Uchida T, Yoshie T, Mizote Y, Ishikawa F, Katsuyama M, and Shibanuma M.
- Journal Title
  
  FEBS Journal
  
  Volume: 286 Issue: 3 Pages: 459-478
- DOI
  10.1111/febs.14671
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08552
[Journal Article] Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene.2011
- Author(s)
  Katsuyama M, Hirai H, Iwata K, Ibi M, Matsuno K, Matsumoto M, Yabe-Nishimura C.
- Journal Title
  
  FEBS J 278
  
  Pages: 964-972
- Data Source
  KAKENHI-PROJECT-21790525
[Journal Article] Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene2011
- Author(s)
  Katsuyama M, Hirai H, Iwata K, Ibi M, Matsuno K, Matsumoto M, Yabe-Nishimura C.
- Journal Title
  
  FEBS Journal
  
  Volume: 278 Pages: 964-972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790525
[Journal Article] NADPH oxidase isoforms and anti-hypertensive effects of atorvastatin demonstrated in two animal models.2009
- Author(s)
  Cui W, Matsuno K, Iwata K, Ibi M, Katsuyama M, Kakehi T, Sasaki M, Ikami K, Zhu K, Yabe-Nishimura C.
- Journal Title
  
  J Pharmacol Sci 111
  
  Pages: 260-268
- NAID
  10026154161
- Data Source
  KAKENHI-PROJECT-20390071
[Journal Article] The AP-1 site is essential for the promoter activity of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme : Possible involvement of the ERK1/2-JunB pathway.2008
- Author(s)
  Cevik MO, Katsuyama M, Kanda S, Kaneko T, Iwata K, Ibi M, Matsuno K, Kakehi T, Cui W, Sasaki M, Yabe-Nishimura C.
- Journal Title
  
  Biochem Biophys Res Commun 374
  
  Pages: 351-355
- Data Source
  KAKENHI-PROJECT-20390071
[Journal Article] Novel transcripts of Nox1 are regulated by alternative promoters and expressed under phenotypic modulation of vascular smooth muscle cells.2006
- Author(s)
  Arakawa N, Katsuyama M, Matsuno K, Urao N, Tabuchi Y, Okigaki M, Matsubara H, Yabe-Nishimura C
- Journal Title
  
  Biochemical Journal 398・2
  
  Pages: 303-310
- Data Source
  KAKENHI-PROJECT-17790173
[Journal Article] Essential role of ATF-1 in induction of NOX1, a catalytic subunit of NADPH oxidase: involvement of mitochondrial resoiratory chain2005
- Author(s)
  Katsuyama M, Fan C, Arakawa N, et al.
- Journal Title
  
  Biochemical Journal 386・2
  
  Pages: 255-261
- Data Source
  KAKENHI-PROJECT-14770036
[Journal Article] Transactivation of the EGF receptor and a PI3 kinase-ATF-1 pathway is involved in the upreeulation of NOX1, a catalytic subunit of NADPH oxidase2005
- Author(s)
  Fan C, Katsuyama M, Nishinaka T, Yabe-Nishimura C.
- Journal Title
  
  FEBS Letters 579・5
  
  Pages: 1301-1305
- Data Source
  KAKENHI-PROJECT-14770036
[Journal Article] PKC-delta mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor : possible involvement of PKCdelta in vascular hypertrophy.2005
- Author(s)
  Fan CY, Katsuyama M, Yabe-Nishimura C.
- Journal Title
  
  Biochemical Journal 390・3
  
  Pages: 761-767
- Data Source
  KAKENHI-PROJECT-17790173
[Journal Article] Characterization of htAKR, a novel gene product in the aldo-keto reductase family specifically expressed in human testis.2004
- Author(s)
  Azuma Y., Soh J., Katsuyama M., Yabe C., et al.
- Journal Title
  
  Molecular Human Reproduction 2
  
  Pages: 209-212
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591706
[Presentation] NOX研究の歴史と阻害薬開発の動向2022
- Author(s)
  勝山真人
- Organizer
  第95回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07326
[Presentation] NOX4/NADPHオキシダーゼによるTGF-β共役受容体エンドグリンの発現制御2019
- Author(s)
  勝山真人、荒川憲昭、矢部千尋
- Organizer
  第92回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K08552
[Presentation] NOX4/NADPHオキシダーゼ由来活性酸素種の標的蛋白の探索2015
- Author(s)
  勝山真人、荒川憲昭、矢部千尋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-25460339
[Presentation] ほ乳類におけるNOX/NADPH oxidaseの生理機能2015
- Author(s)
  勝山真人、矢部千尋
- Organizer
  BMB2015（第38回日本分子生物学会年会・第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25460339
[Presentation] NOX/NADPHオキシダーゼの多彩な機能と病態への関与2014
- Author(s)
  勝山真人
- Organizer
  第31回臨床フリーラジカル会議
- Place of Presentation
  亀岡
- Year and Date
  2014-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-25460339
[Presentation] クリオキノールの細胞毒性にNOX4/NADPHオキシダーゼが関与する2010
- Author(s)
  勝山真人、矢部千尋
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21790525
[Presentation] NOX1/NADPHオキシダーゼのマスト細胞における発現2009
- Author(s)
  勝山真人、谷川成佑、田中智之、阪中麻利子、矢部千尋
- Organizer
  第82回日本薬理学会年会.
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19790192
[Presentation] NOX1/NADPHオキシダーゼのマスト細胞における発現2009
- Author(s)
  勝山真人、谷川成佑、田中智之、阪中麻利子、矢部千尋
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19790192

1. YABE Chihiro (70150571)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
2. IWATA Kazumi (60305571)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. SOU Jintetsu (40305587)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. ARAKAWA Noriaki (60398394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. KAWAUCHI Akihiro (90240952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MIKI Tsuneharu (10243239)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HIRAYAMA Aki (20323298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. KAKEHI Tomoko (20433279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. NAKAMURA Naoto (40227921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIZUTANI Yoichi (10243031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松野邦晴 (50420708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 西村千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

Katsuyama Masato 勝山 真人

KATSUYAMA Masato 勝山 真人

Research Projects

Research Products

Co-Researchers

A study on molecular mechanisms of quinoform-induced cell death dependent on copper and oxidative stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on mechanisms of exacerbation of tissue fibrogenesis by NOX4-derived reactive oxygen speciesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of new oxidative signaling involved in tissue fibrogenesis and its application to therapeutic strategyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on signaling pathways associated with NOX4/NADPH oxidase for the development of new antifibrotic drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the molecular basis of the exertion of adverse effects of drugs mediated by regulation of NADPH oxidase activitiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on the involvement of NADPH oxidase in allergic diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血管平滑筋に発現する種特異的な活性酸素産生酵素の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Paradoxical roles of the aldehyde-metabolizing enzyme, aldose reductase in cardioprotection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of the sexual dysfunction by diabetes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プロスタノイドによる血管平滑筋NADPHオキシダーゼの活性化機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of insulin - like growth factor binding protein-3 (IGFBP-3) on diabetes - induced erectile dysfunction (ED)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS-activated cancer cells.2019

Author(s)

Journal Title

Katsuyama Masato 勝山真人

KATSUYAMA Masato 勝山真人