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Mizuno Noriyoshi  水野 智仁

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MIZUNO Noriyoshi  水野 智仁

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Researcher Number 60325181
Other IDs
External Links
Affiliation (Current) 2025: 広島大学, 医系科学研究科(歯), 教授
Affiliation (based on the past Project Information) *help 2020 – 2025: 広島大学, 医系科学研究科(歯), 教授
2016 – 2020: 広島大学, 病院(歯), 講師
2015: 広島大学, 大学病院, 講師
2014: 広島大学, 大学院医歯薬保健学研究院(歯), 助教
2012 – 2014: 広島大学, 医歯薬保健学研究院(歯), 助教 … More
2012 – 2013: 広島大学, 医歯薬保健学研究院, 助教
2012: 広島大学, 大学院・医歯薬保健学研究院, 助教
2011: 広島大学, 医歯(薬)学総合研究科, 助教
2011: 広島大学, 医歯薬学総合研究科, 助教
2010 – 2011: Hiroshima University, 大学院・医歯薬学総合研究科, 助教
2009: 広島大学, 医歯薬学総合研究科, 助教
2009: Hiroshima University, 大学院・医歯学薬学総合研究科, 助教
2007 – 2008: Hiroshima University, Graduate school of Biomedical Sciences, Assistant Professor
2005 – 2006: 広島大学, 大学院医歯薬学総合研究科, 助手
2002 – 2005: Hiroshima Univ. Graduate Sch. Biomed. Sci., Research Associate, 大学院・医歯薬学総合研究科, 助手
2001: 広島大学, 歯学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Periodontal dentistry / Basic Section 57030:Conservative dentistry-related / Periodontology / Periodontal dentistry
Except Principal Investigator
Periodontal dentistry / Basic Section 57030:Conservative dentistry-related / Periodontal dentistry / Basic Section 57080:Social dentistry-related / Periodontology / Dental engineering/Regenerative dentistry
Keywords
Principal Investigator
侵襲性歯周炎 / 原因遺伝子 / 骨関連タンパク質 / 遺伝子改変マウス / 浸襲性歯周炎 / ゲノム編集 / エクソームシークエンス / KIマウス / 硬組織関連タンパク質 / 歯周靱帯細胞 … More / メカニカルストレス / レプチン / 歯周組織再生 / ヒト歯周靱帯細胞 / NT-4 / NT-3 / BDNF / NGF / 機械的伸展力負荷 / エナメル蛋白質 / 骨関連蛋白質 / ヒト歯周靭帯線維芽細胞 / データベース / 質量分析 / 2次元電気泳動 / エナメルタンパク質 / ヒトマラッセ上皮細胞 / ヒト歯周靱帯線維芽細胞 … More
Except Principal Investigator
歯周組織再生 / 間葉系幹細胞 / C-MSCs / 間葉系幹細胞集塊 / HIF-1α / DEC1 / periodontal tissue regeneration / 歯周組織再生療法 / 歯肉線維芽細胞 / 歯周靭帯細胞 / セメント芽細胞 / 再生医療 / 口腔保健 / 指標 / 線維化 / インテグリン / 特発性歯肉線維腫症 / 薬物性歯肉増殖症 / 歯周組織構成細胞 / microRNA / エクソソーム / ヒストン脱アセチル化酵素 / ヒストンアセチル化 / HDAC / 立体複合化 / iPS細胞 / 神経堤細胞由来間葉系幹細胞 / 3Dプリンター / 3Dプリンター / 立体組織化 / 3Dバイオプリンター / 立体化 / C-MSC / 細胞集塊 / 凍結保存 / 免疫制御能 / 立体組織 / 歯周組織再生治療 / サイトカイン / 再生歯学 / 転写因子 / micro RNA / osteogenesis / mesenchymal stem cell / hypoxia / clock genes / HIF1α / 骨分化 / 低酸素 / 時計遺伝子 / periodontal osseous defect / pre clinical study / green fluorescent protein / osteopontin / Atelocollagen / regenerative medicine / mesenchymal stem cells / GFP / コラーゲンゲル / 実験的歯周組織欠損 / 骨シアロプロテイン / 歯周組織欠損炎症モデル / 歯周組織欠損 / 前臨床試験 / green fluorescent / オステオポンチン / アテロコラーゲン / 骨髄間葉系幹細胞 / cementum repair / epithelial cell rests of Malassez / 培養細胞 / セメント質再生 / マラッセ上皮遺残 / periostium / periodontal regeneration / gingival epithelial cell / gingival fibroblast / stress proteins / molecular chaperones / 骨膜結合組織 / 歯肉上皮細胞 / ストレス蛋白 / シャペロン分子 / セメント質形成 / マイクロRNA / マイクロRNA / 関連遺伝子 / 劣性遺伝 / 侵襲性歯周炎 / 宿主応答 / オーダーメード / サイトカイン療法 / siRNA / MyD-88 / c-Raf / trkB / Elk-1 / 42 / p44 / 抗炎症作用 / 骨・セメント質関連タンパク質 / 歯周組織 / 脳由来神経栄養因子 / 歯周外科学 / ヒト歯周靭帯由来細胞 / マイクロアレイ / ヒト歯周靱帯由来細胞 / 象牙質 / ヒトセメント芽細胞 Less
  • Research Projects

    (24 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (29 People)
  •  MMD2に変異を有する侵襲性歯周炎患者に対する新規特異的分子標的の探索Principal Investigator

    • Principal Investigator
      水野 智仁
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  Development of core indicators and item bank for oral health assessment

    • Principal Investigator
      内藤 真理子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Hiroshima University
  •  侵襲性歯周炎の新規責任遺伝子の同定と病態解析Principal Investigator

    • Principal Investigator
      水野 智仁
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  インテグリンを標的とした薬物性歯肉増殖症の新規治療法の開発

    • Principal Investigator
      岡信 愛
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  Elucidation of mechanism for periodontal regeneration via exosome and application for periodontal regenerative therapy

    • Principal Investigator
      Iwata Tomoyuki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  Elucidation of the pathophysiology of aggressive periodontitis using MMD2 mutant micePrincipal Investigator

    • Principal Investigator
      Mizuno Noriyoshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  Development of periodontal tissue regenerative therapy by using neural crest-derived MSCs and cell clumps culture technique

    • Principal Investigator
      Kurihara Hidemi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  Establishment of order-made periodontal regenerative therapy based on micro RNA profile

    • Principal Investigator
      Iwata Tomoyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Hiroshima University
  •  Identification of reated gene and pathologic analysis in familial aggressie periodontitisPrincipal Investigator

    • Principal Investigator
      Mizuno Noriyoshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Hiroshima University
  •  The development of periodontal regenerative cell therapy by using clumps of MSCs/ECM complexes

    • Principal Investigator
      Hidemi Kuriha
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontology
    • Research Institution
      Hiroshima University
  •  Induction of cementoblastic differentiation from mesenchymal stem cells and cementogenesis on dentin surface

    • Principal Investigator
      KURIHARA HIDEMI
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  Identification of responsible gene involved with aggressive periodontitis by homozygosity haplotype analysisPrincipal Investigator

    • Principal Investigator
      MIZUNO Noriyoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  Detection of disease causing genes of aggressive periodontitis by recessive analysis

    • Principal Investigator
      KURIHARA Hidemi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  The basic study for the progression of the order-made medicine by cytokines for periodontal tissue regeneration

    • Principal Investigator
      KURIHARA Hidemi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  Identification of responsible gene involved with aggressive periodontitis in consanguinityPrincipal Investigator

    • Principal Investigator
      MIZUNO Noriyoshi
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  Development of periodontal tissue regeneration using leptinPrincipal Investigator

    • Principal Investigator
      MIZUNO Noriyoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  脳由来神経栄養因子を用いた歯周組織再生療法の確立

    • Principal Investigator
      栗原 英見
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  Investigation of the mechanism of osteogenic induction by clock genes

    • Principal Investigator
      FUJIOKA Daisuke, 岩田 倫幸
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  ヒトセメント芽細胞の特異的マーカーの探究

    • Principal Investigator
      KURIHARA Hidemi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  神経栄養因子を用いた歯周組織再生療法の開発Principal Investigator

    • Principal Investigator
      水野 智仁
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  Periodontal tissue regeneration by transplantation of own bone marrow mesenchymal stem cells

    • Principal Investigator
      KAWAGUCHI Hiroyuki
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  歯周靭帯に由来する上皮間葉系細胞相互作用に及ぼすメカニカルストレスの影響Principal Investigator

    • Principal Investigator
      水野 智仁
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Hiroshima University
  •  Study of roles of epithelial cell rests of Malassez in periodontal regeneration

    • Principal Investigator
      OGAWA Tetsuji
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  A new regenerative therapy of periodontal tissue using periostium and molecular chaperones induction

    • Principal Investigator
      KAWAGUCHI Hiroyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY

All 2022 2020 2019 2017 2011 2010 2008 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Xenotransplantation of cryopreserved human clumps of mesenchymal stem cells/extracellular matrix complexes pretreated with IFN-γ induces rat calvarial bone regeneration2022

    • Author(s)
      Ogawa Tomoya、Kajiya Mikihito、Horikoshi Susumu、Yoshii Hiroki、Yoshino Mai、Motoike Souta、Morimoto Shin、Sone Hisakatsu、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi
    • Journal Title

      Regenerative Therapy

      Volume: 20 Pages: 117-125

    • DOI

      10.1016/j.reth.2022.04.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-20K09975, KAKENHI-PROJECT-21K21066
  • [Journal Article] Clumps of mesenchymal stem cells/extracellular matrix complexes directly reconstruct the functional periodontal tissue in a rat periodontal defect model2022

    • Author(s)
      Sone Hisakatsu、Kajiya Mikihito、Takeda Katsuhiro、Sasaki Shinya、Horikoshi Susumu、Motoike Souta、Morimoto Shin、Yoshii Hiroki、Yoshino Mai、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi
    • Journal Title

      Journal of Tissue Engineering and Regenerative Medicine

      Volume: 16 Issue: 10 Pages: 945-955

    • DOI

      10.1002/term.3343

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-20K09975, KAKENHI-PROJECT-21K21066, KAKENHI-PROJECT-23K24533
  • [Journal Article] Regulation of osteogenesis in bone marrow‐derived mesenchymal stem cells via histone deacetylase 1 and 2 co‐cultured with human gingival fibroblasts and periodontal ligament cells2022

    • Author(s)
      Iwata Tomoyuki、Kaneda‐Ikeda Eri、Takahashi Keita、Takeda Katsuhiro、Nagahara Takayoshi、Kajiya Mikihito、Sasaki Shinya、Ishida Shu、Yoshioka Minami、Matsuda Shinji、Ouhara Kazuhisa、Fujita Tsuyoshi、Kurihara Hidemi、Mizuno Noriyoshi
    • Journal Title

      Journal of Periodontal Research

      Volume: 58 Issue: 1 Pages: 83-96

    • DOI

      10.1111/jre.13070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-20K09975
  • [Journal Article] Optineurin regulates osteoblastogenesis through STAT12020

    • Author(s)
      Mizuno Noriyoshi、Iwata Tomoyuki、Ohsawa Ryosuke、Ouhara Kazuhisa、Matsuda Shinji、Kajiya Mikihito、Matsuda Yukiko、Kume Kodai、Tada Yui、Morino Hiroyuki、Yoshimoto Tetsuya、Ueki Yasuyoshi、Mihara Keichiro、Sotomaru Yusuke
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 525(4) Issue: 4 Pages: 889-894

    • DOI

      10.1016/j.bbrc.2020.03.028

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02978, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K18999
  • [Journal Article] Cox2-mediated PGE2 production via p38/JNK-c-fos signaling inhibits cell apoptosis in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes2020

    • Author(s)
      Komatsu Nao、Kajiya Mikihito、Morimoto Shin、Motoike Souta、Yoshii Hiroki、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi、Kurihara Hidemi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 530 Issue: 2 Pages: 448-454

    • DOI

      10.1016/j.bbrc.2020.05.100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-18H02977, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K19030
  • [Journal Article] Aggressive periodontitis and NOD2 variants2020

    • Author(s)
      Mizuno Noriyoshi, Kume Kodai, Nagatani Yukiko, Matsuda Shinji, Iwata Tomoyuki, Ouhara Kazuhisa, Kajiya Mikihito, Takeda Katsuhiro, Matsuda Yukiko, Tada Yui, Ohsawa Ryosuke, Morino Hiroyuki, Mihara Keichiro, Fujita Tsuyoshi, Kawaguchi Hiroyuki, Shiba Hideki, Kawakami Hideshi, Kurihara Hidemi
    • Journal Title

      Journal of Human Genetics

      Volume: 65(10) Issue: 10 Pages: 841-846

    • DOI

      10.1038/s10038-020-0777-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02978, KAKENHI-PROJECT-18K09599
  • [Journal Article] Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis2019

    • Author(s)
      Motoike Souta、Kajiya Mikihito、Komatsu Nao、Horikoshi Susumu、Ogawa Tomoya、Sone Hisakatsu、Matsuda Shinji、Ouhara Kazuhisa、Iwata Tomoyuki、Mizuno Noriyoshi、Fujita Tsuyoshi、Ikeya Makoto、Kurihara Hidemi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 16 Pages: 3970-3970

    • DOI

      10.3390/ijms20163970

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-19K19030, KAKENHI-PROJECT-18H02977, KAKENHI-PROJECT-18J13726
  • [Journal Article] MSC/ECM cellular complexes induce periodontal tissue regeneration2017

    • Author(s)
      Manabu Takewaki, Mikihito Kajiya*, Katsuhiro Takeda, Shinya Sasaki, Souta Motoike, Nao Komatsu, Shinji Matsuda, Kazuhisa Ouhara, Noriyoshi Mizuno, Tsuyoshi Fujita, and Hidemi Kurihara
    • Journal Title

      Journal of Dental Research

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H05053
  • [Journal Article] Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration2017

    • Author(s)
      Kei Takeshita, Souta Motoike1, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Noriyoshi Mizuno, Tsuyoshi Fujita, and Hidemi Kurihara
    • Journal Title

      Stem Cell Research & Therapy

      Volume: 8:101 Issue: 1 Pages: 101-101

    • DOI

      10.1186/s13287-017-0550-1

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H07004, KAKENHI-PROJECT-15K11215, KAKENHI-PROJECT-15K11390
  • [Journal Article] Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration2017

    • Author(s)
      Kei Takeshita, Souta Motoike, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Noriyoshi Mizuno, Tsuyoshi Fujita, and Hidemi Kurihara
    • Journal Title

      Stem Cell Research & Therapy

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05053
  • [Journal Article] Proteome analysis of proteins related to aggressive periodontitis combined with neutrophil chemotaxis dysfunction.2011

    • Author(s)
      Mizuno N, Niitani M, Shiba H, et al.
    • Journal Title

      Journal of Clinical Periodontology

      Volume: 38(4) Pages: 310-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21792122
  • [Journal Article] 侵襲性歯周炎に関する最近の話題2011

    • Author(s)
      水野智仁、八木亮一、岩田倫幸, 他
    • Journal Title

      広島歯科医学雑誌

      Volume: 38(1) Pages: 10-16

    • Data Source
      KAKENHI-PROJECT-21792122
  • [Journal Article] Proteome analysis of proteins related to aggressive periodontitis combined withneutrophil chemo taxis dysfunction2011

    • Author(s)
      Mizuno N, Niitani M, Shiba H, Iwata T, Hayashi I, Kawaguchi H, Kurihara H.
    • Journal Title

      J Clin Periodontol

      Volume: 38 Issue: 4 Pages: 310-7

    • DOI

      10.1111/j.1600-051x.2010.01693.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310035, KAKENHI-PROJECT-21390557
  • [Journal Article] The antimicrobial peptide LL37 induces the migration of human pulp cells : a possible adjunct for regenerative endodontics2010

    • Author(s)
      Kajiya M, Shiba H, Komatsuzawa H, Ouhara K, Fujita T, Takeda K, Uchida Y, Mizuno N, KawaguchiH, Kurihara H
    • Journal Title

      J Endod

      Volume: 36(6) Pages: 1009-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390557
  • [Journal Article] Humoral factors released from human periodontal ligament cells influence calcification and proliferation in human bone marrow mesenchymal stem cells2008

    • Author(s)
      N, Mizuno, Y, Ozeki, H, Shiba et al
    • Journal Title

      Journal of periodontology 79(12)

      Pages: 2361-2370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791614
  • [Journal Article] 自家骨髄間葉系幹細胞移植による歯周組織再生療法の開発2005

    • Author(s)
      河口浩之, 水野智仁, 栗原英見, 他
    • Journal Title

      再生医療 4・1

      Pages: 69-77

    • Data Source
      KAKENHI-PROJECT-15390647
  • [Journal Article] 骨髄間葉系幹細胞移植による歯周組織再生治療2004

    • Author(s)
      河口浩之, 水野智仁, 栗原英見, 他
    • Journal Title

      ザ・クインテッセンス 23・9

      Pages: 57-61

    • Data Source
      KAKENHI-PROJECT-15390647
  • [Journal Article] 骨髄間葉系幹細胞を用いた歯周組織再生医療2004

    • Author(s)
      河口浩之, 水野智仁, 栗原英見, 他
    • Journal Title

      日本歯科医師会雑誌 57・4

    • Data Source
      KAKENHI-PROJECT-15390647
  • [Journal Article] Enhancement of periodontal tissue regeneration by transplantation of bone marrow mesenchymal stem cells2004

    • Author(s)
      Kawaguchi H, Mizuno T, Kurihara H et al.
    • Journal Title

      Journal of Periodontology 75

      Pages: 1281-1287

    • Data Source
      KAKENHI-PROJECT-15390647
  • [Journal Article] Human autologous serum obtained using a completely closed bag system as a substitute for foetal calf serum in human mesenchymal stem cell cultures

    • Author(s)
      Noriyoshi Mizuno
    • Journal Title

      Cell Biology Internathional (In press)

    • Data Source
      KAKENHI-PROJECT-16791314
  • [Presentation] Clumps of MSCs/ECM complexes は自身の分化能によって歯周組織再生を促進する2022

    • Author(s)
      曽根 久勝,加治屋 幹人, 佐々木 慎也, 堀越 励, 小川 智也, 森本 慎 , 吉井 寛毅, 吉野 舞, 松田 真司, 岩田 倫幸, 應原 一久, 水野 智仁
    • Organizer
      第65回春季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K09975
  • [Presentation] 3次元培養間葉系幹細胞集塊を用いた骨髄脂肪組織様in vitroモデルの開発2022

    • Author(s)
      吉野 舞,加治屋 幹人, 森本 慎 , 吉井 寛毅, 堀越 励, 曽根 久勝, 岩田 倫幸, 應原 一久, 松田 真司, 水野 智仁
    • Organizer
      第43回日本炎症・再生学会
    • Data Source
      KAKENHI-PROJECT-20K09975
  • [Presentation] 軟骨分化・骨便化誘導を併用した間葉系幹細胞集塊 Clumps of MSCs/ECM complexesの移植は軟骨内骨化の様式を経て骨再生を促進する2022

    • Author(s)
      森本 慎,加治屋 幹人, 吉井 寛毅, 吉野 舞, 岩田 倫幸, 水野 智仁
    • Organizer
      第40回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K09975
  • [Presentation] 侵襲性歯周炎の家族内発症を考える2020

    • Author(s)
      水野智仁
    • Organizer
      第5回日本歯周病学会近畿地区臨床研修会
    • Data Source
      KAKENHI-PROJECT-18H02978
  • [Presentation] Clumps of a mesenchymal stem cell/extracellular matrix complex induces periodontal tissue regeneration2017

    • Author(s)
      竹脇学、加治屋幹人、武田克浩、佐々木慎也、本池総太、小松奈央、松田真司、應原一久、水野智仁、藤田 剛、栗原英見
    • Organizer
      第12回アジア太平洋歯周病学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05053
  • [Presentation] 間葉系幹細胞の細胞機能制御に関するmicro RNAの探索2017

    • Author(s)
      岩田倫幸、永原隆吉、兼田英里、吉岡みなみ、水野智仁、柴 秀樹、栗原英見
    • Organizer
      第59回春季日本歯周病学会学術大会
    • Place of Presentation
      鹿児島市 かごしま県民交流センター
    • Year and Date
      2017-05-20
    • Data Source
      KAKENHI-PROJECT-15K11215
  • [Presentation] 間葉系幹細胞から歯周組織構成細胞への分化制御遺伝子の探索2017

    • Author(s)
      岩田倫幸、永原隆吉、池田英里、八木亮一、間 悠介、小西昭弘、吉岡みなみ、石田 充、水野智仁、柴 秀樹、栗原英見
    • Organizer
      第59回秋季日本歯周病学会学術大会
    • Place of Presentation
      新潟市 朱鷺メッセ
    • Year and Date
      2017-10-07
    • Data Source
      KAKENHI-PROJECT-15K11215
  • 1.  KURIHARA Hidemi (40161765)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 8 results
  • 2.  IWATA Tomoyuki (30418793)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 6 results
  • 3.  KAWAGUCHI Hiroyuki (10224750)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 4.  SHIBA Hideki (60260668)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 5.  FUJITA Tsuyoshi (80379883)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 6.  KAWAKAMI Hideshi (70253060)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  加治屋 幹人 (00633041)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 8.  KATO Kouichi (50283875)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  OUHARA Kazuhisa (80550425)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 10.  OGAWA Tetsuji (50112206)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TAKATA Takashi (10154783)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  FUJIOKA Daisuke (20379879)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  松田 真司 (30611321)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  TAKEDA Katsuhiro (10452591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  HINO Takamune (20274102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HAYASHIDA Kouichi (10437585)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  UCHIDA Yuushi (40363080)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  YOSHINO Hiroshi (50240338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  兼田 英里 (30736426)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  池谷 真 (20442923)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  岡信 愛 (00806581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  横崎 恭之 (80210607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  内藤 真理子 (10378010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  若井 建志 (50270989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  吉田 光由 (50284211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  西村 瑠美 (80758219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  MORINO Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 28.  HAYASHI Ikue
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  松田 由喜子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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