SHIMIZU Hiroyasu 清水宏泰

Researcher Number	60340551
Other IDs
Affiliation (based on the past Project Information) *help	2015: 大阪医科大学, 医学部, 准教授 2010 – 2013: 大阪医科大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Hygiene Except Principal Investigator Risk sciences of radiation/Chemicals / Hygiene
Keywords	Principal Investigator イオンチャネル / 環境毒性 / 水生動物 / スクリーニング / バイオアッセイ / 毒性 / パッチクランプ / 化学物質 / 水生生物 / メダカ … More Except Principal Investigator … More DT40細胞 / データマイニング / 情報学 / はいスループットスクリーニング / 小核試験 / レギュラトリーサイエンス / ハイスループットスクリーニング / 小核実験 / 変異原 / 発がん物質 / 遺伝毒物学 / 化審法 / 有害化学物質 / DNA修復機能 / ハイスループット / メダカ / 遺伝子修復経路 / 環境化学物質 / スクリーニング / DNA障害 / 変異原性 / 発がん性 / DNA 修復経路 / バイオアッセイ / 化学物質 Less

Establishment of high-throughput screening of toxic chemical compounds.
- Principal Investigator
  
  Takeda Shunichi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Assessment of the combined effect of chemicals on the ion channels of freshwater fish.Principal Investigator
- Principal Investigator
  
  SHIMIZU Hiroyasu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene
- Research Institution
  Osaka Medical College
Assessment of combined effect of chemicals with using mutant DT40s and gene knock out Medaka.
- Principal Investigator
  
  KOUNO Kouichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Osaka Medical College

All 2015 2014 2013 2011 2010

All Journal Article Presentation

[Journal Article] Distinct DNA damage spectra induced by ionizing radiation in normoxic and hypoxic cells.2015
- Author(s)
  Shimizu N, Ooka M, Takagi T, Takeda S, Hirota K.
- Journal Title
  
  Radiation Res
  
  Volume: 184(4) Issue: 4 Pages: 442-8
- DOI
  10.1667/rr14117.1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26116518, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-25281021
[Journal Article] A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes.2014
- Author(s)
  Mohiuddin, Keka IS, Evans TJ, Hirota K, Shimizu H, Kono K, Takeda S, Hirano S
- Journal Title
  
  Arch Toxicol.
  
  Volume: 88 Issue: 1 Pages: 145-160
- DOI
  10.1007/s00204-013-1084-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23221005, KAKENHI-PUBLICLY-24114509, KAKENHI-PROJECT-25281021
[Journal Article] Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.2014
- Author(s)
  Maede Y, Shimizu H, Fukushima T, Kogame T, Nakamura T, Miki T, Takeda S, Pommier Y, Murai J
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 13 Issue: 1 Pages: 214-220
- DOI
  10.1158/1535-7163.mct-13-0551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-25740016
[Journal Article] A stable ATP binding to the nucleotide binding domain is important for reliable gating cycle in an ABC transporter CFTR.2010
- Author(s)
  Shimizu H, Yu YC, Kono K, Kubota T, Yasui M, Li M, Hwang TC, Sohma Y.
- Journal Title
  
  J.Physiol Sci
  
  Volume: 60 Pages: 353-62
- NAID
  10027504627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390126
[Journal Article] Optimization of the degenerated interfacial ATP binding site improves the function of disease-related mutant cystic fibrosis transmembrane conductance regulator (CFTR) channels.2010
- Author(s)
  Tsai MF, Jih KY, Shimizu H, Li M, Hwang TC.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 37663-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390126
[Presentation] 酸素の有無による電離放射線照射時のDNA損傷の種類の解析2015
- Author(s)
  大岡　正人、清水　直登、高木　季代、武田　俊一、廣田　耕志
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-23221005
[Presentation] 遺伝子破壊ニワトリBリンパ球を用いたクロロ酢酸のDNA障害とアポトーシス阻害の検討2013
- Author(s)
  清水　宏泰
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23221005
[Presentation] 遺伝子破壊ニワトリ B リンパ球を用いたクロロ酢酸の DNA 障害とアポトーシス阻害の検討2013
- Author(s)
  清水宏泰、モヒウディン、武田俊一、河野公一
- Organizer
  第83回日本衛生学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22390126
[Presentation] 遺伝子破壊ニワトリBリンパ球を用いたクロロ酢酸のDNA障害とアポトーシス阻害の検討2013
- Author(s)
  清水宏泰
- Organizer
  第83回日本衛生学会総会
- Place of Presentation
  金沢大学（金沢）
- Data Source
  KAKENHI-PROJECT-22390126
[Presentation] 産業現場で使用される有害化学物質スクリーニングとしてのニワトリBリンパ球(DT40)によるバイオアッセイの確立2011
- Author(s)
  清水宏泰、栗田晃宏、Mohiuddin、武田俊一、河野公一
- Organizer
  近畿産業衛生学会
- Place of Presentation
  奈良県
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-22390126
[Presentation] 産業現場で使用される有害化学物質スクリーニングとしてのニワトリBリンパ球(DT40)によるバイオアッセイの確立2011
- Author(s)
  清水宏泰、武田俊一, 他と河野公一
- Organizer
  第51回近畿産業衛生学会
- Place of Presentation
  奈良県文化会館(奈良県)
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23221005

1. TAKEDA Shunichi (60188191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. KOUNO Kouichi (30111016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. HIROTA Kouji (00342840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. YAMADA Ryo (50301106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OKADA Tetsuya (70378529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SASANUMA Hiroyuki (00531691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAHASHI Ryosuke (90216771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMIZU Hiroyasu 清水 宏泰

Research Projects

Research Products

Co-Researchers

Establishment of high-throughput screening of toxic chemical compounds.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Assessment of the combined effect of chemicals on the ion channels of freshwater fish.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Assessment of combined effect of chemicals with using mutant DT40s and gene knock out Medaka.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Distinct DNA damage spectra induced by ionizing radiation in normoxic and hypoxic cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A stable ATP binding to the nucleotide binding domain is important for reliable gating cycle in an ABC transporter CFTR.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Optimization of the degenerated interfacial ATP binding site improves the function of disease-related mutant cystic fibrosis transmembrane conductance regulator (CFTR) channels.2010

Author(s)

Journal Title

Data Source

[Presentation] 酸素の有無による電離放射線照射時のDNA損傷の種類の解析2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 遺伝子破壊ニワトリBリンパ球を用いたクロロ酢酸のDNA障害とアポトーシス阻害の検討2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 遺伝子破壊ニワトリ B リンパ球を用いた クロロ酢酸の DNA 障害とアポトーシス阻害の検討2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 遺伝子破壊ニワトリBリンパ球を用いたクロロ酢酸のDNA障害とアポトーシス阻害の検討2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 産業現場で使用される有害化学物質スクリーニングとしてのニワトリBリンパ球(DT40)によるバイオアッセイの確立2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 産業現場で使用される有害化学物質スクリーニングとしてのニワトリBリンパ球(DT40)によるバイオアッセイの確立2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

SHIMIZU Hiroyasu 清水宏泰

[Presentation] 遺伝子破壊ニワトリ B リンパ球を用いたクロロ酢酸の DNA 障害とアポトーシス阻害の検討2013