WATADA Hirotaka 綿田裕孝

Researcher Number	60343480
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 順天堂大学, 大学院医学研究科, 教授 2017 – 2020: 順天堂大学, 医学(系)研究科(研究院), 教授 2010 – 2017: Juntendo University, 医学部, 教授 2007 – 2011: Juntendo University, Dept. of Medicien, Associate Professor 2008: 順天堂大学, 医学部, 先任准教授 2006: 順天堂大学, 医学部, 助教授 2002 – 2005: 順天堂大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Metabolomics / Biological Sciences / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 54040:Metabolism and endocrinology-related / Biological Sciences / Metabolomics Except Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related / Basic Section 54040:Metabolism and endocrinology-related / Applied health science … More / Biological Sciences / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Environmental physiology (including Physical medicine and Nutritional physiology) / Metabolomics Less
Keywords	Principal Investigator 膵β細胞 / オートファジー / 糖尿病 / インスリン / ２型糖尿病 / 膵ラ氏島 / 発生 / 分化 / 膵α細胞 / グルカゴン … More / Ptc / 細胞分化 / 動脈硬化 / 2型糖尿病 / 血管内皮 / VEGF-A / 骨髄移植 / 膵臓 / 転写因子 / Smad / neurogenin 3 / Activin / マイトファジー / 細胞運命 / lineage tracing / 膵島 / 細胞死 / 大動脈瘤 / 平滑筋細胞 / 細胞老化 / Type 2 Diabetes / Hedgehog / Insulin / Islet / シグナル / 膵発生 / パッチド / ヘッジホッグ / 発生分化 / ApoE / 妊娠糖尿病 / 細胞増殖 / 妊娠 / セロトニン / 膵 ss細胞 / エネルギー・糖質代謝異常 / アミロイド / 糖脂質代謝 / アミリン / アポトーシス / インスリン抵抗性 / Neurogenin3 / Pur1 / Nkx2.2 … More Except Principal Investigator 糖尿病 / 膵β細胞 / オートファジー / インスリン / β細胞 / インスリン抵抗性 / インスリン分泌 / Atg7 / オートファジー不全 / p62 / Cre recombinase / VEGF-A / 骨格筋細胞内脂質 / 発生 / 周産期 / 妊娠糖尿病 / 耐糖能異常 / 妊娠 / 代謝性疾患 / 血液疾患 / 神経変性疾患 / 選択的オートファジー / 糖尿病再生医療 / 前駆細胞 / Neurog3 / 擬絶食療法 / 再生医療 / β細胞新生 / heterogeneity / インスリン分泌不全 / db/dbマウス / sick beta cells / spatial heterogeneity / β細胞不全 / β-cell heterogeneity / sick β cells / 代謝 / 認知症 / 骨格筋機能 / 脳血管障害 / 認知機能 / 介護予防 / フレイル / 介護 / 無症候性ラクナ梗塞 / サルコペニア / 筋力 / Sprr1a / 膵α細胞 / グルカゴン分泌 / グルカゴン / α細胞 / INSULIN RESISTANCE / INTRACELLULAR LIPID / SNP / DIABETES MELLITUS / PREVENTION OF DISEASE / OXIDATIVE STRESS / 疫病予防 / 細胞内脂質 / 遺伝子多型 / 疾病予防 / 酸化ストレス / Insulin / Diabetes Mellitus / Pancreatic microcirculation / Pancreatic β cell / Cre recombinas / 膵微少循環 / 血管内皮 / 膵微小循環 / 亜鉛トランスポーター / 膵ベータ細胞 / 糖代謝 / 2型糖尿病 / トランスポーター / 亜鉛 / アディポネクチン / 身体活動 / 転写因子 / 分化 / アセチル化蛋白 / 発生学 / CD9 / インテグリン Less

Mechanisms of autophagy regulation and its disruption in pancreatic beta cellsPrincipal Investigator
- Principal Investigator
  
  綿田裕孝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Juntendo University
Pathophysiology of pancreatic beta cell insufficiency using a novel in vivo gene screening methodPrincipal Investigator
- Principal Investigator
  
  綿田裕孝
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Juntendo University
Interdisciplinary research on autophagy: From working principles to pathophysiology
- Principal Investigator
  
  小松雅明
- Project Period (FY)
  2023 – 2029
- Research Category
  
  Fund for the Promotion of Joint International Research (International Leading Research )
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
妊娠期膵β細胞量増大および妊娠糖尿病発症におけるオートファジーの意義の解明
- Principal Investigator
  
  池田富貴
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Juntendo University
Discovery of new anti-diabetic drugs activating autophagy in beta cellsPrincipal Investigator
- Principal Investigator
  
  Watada Hirotaka
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Juntendo University
Molecular Mechanism of beta cell failure due to autophagic failurePrincipal Investigator
- Principal Investigator
  
  Hirotaka Watada
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Juntendo University
Chronology of beta-cell failure with a novel time-resolved reporter system in mice
- Principal Investigator
  
  Miyatsuka Takeshi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Juntendo University
Optimization of beta-cell reprogramming driven by fasting-mimicking diet
- Principal Investigator
  
  Miyatsuka Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kitasato University
  Juntendo University
Loss of p62 in pancreatic beta cells under autophagy deficiency had little effect on glucose tolerance and insulin secretion.
- Principal Investigator
  
  Ikeda Fuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Juntendo University
Research on "quantity" and "quality" of skeletal muscle aiming at comprehensive prevention of long-term care
- Principal Investigator
  
  Kawamori Ryuzo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
Cellular autophagy in alpha cells plays a role in the maintenance of islet architecture.
- Principal Investigator
  
  Goto Hiromasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
Autophagy deficiency cumulatively causes beta-cell failure.
- Principal Investigator
  
  Komiya Koji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
Autophagic failure in isletsPrincipal Investigator
- Principal Investigator
  
  WATADA HIROTAKA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
Autophagic failure of smooth muscle cellsPrincipal Investigator
- Principal Investigator
  
  綿田裕孝
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Mechanism of pancreatice alpha cell neogenesis and maturationPrincipal Investigator
- Principal Investigator
  
  Watada Hirotaka
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
膵β細胞オートファジー不全とp62陽性の封入体形成Principal Investigator
- Principal Investigator
  
  綿田裕孝
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Alteration of cellular status in diabetes and autophagyPrincipal Investigator
- Principal Investigator
  
  Watada Hirotaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
Maturation Process of beta cells using New-timer mousePrincipal Investigator
- Principal Investigator
  
  Hirotaka Watada
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
Physiological substrate of beta cell autophagyPrincipal Investigator
- Principal Investigator
  
  WATADA Hirotaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
Regulation of the pancreatic beta-cell proliferation during non-pregnant periodPrincipal Investigator
- Principal Investigator
  
  WATADA Hirotaka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
Role of zinc transporters in beta-cell-autophagy induction
- Principal Investigator
  
  FUJITANI Yoshio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
2型糖尿病の原因因子としての膵β細胞オートファジー機能不全Principal Investigator
- Principal Investigator
  
  綿田裕孝
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
New insulin resistance regulatory factor "susceptibility to fat loading"
- Principal Investigator
  
  KAWAMORI Ryuzo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Mechanism of pancreatic beta cell expansion by bone marrow transplantationPrincipal Investigator
- Principal Investigator
  
  WATADA Hirotaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
Role of Hedgehog Signaling on the differentiation of pancreas and pancreatic beta-cell functionPrincipal Investigator
- Principal Investigator
  
  WATADA Hirotaka
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
高脂肪食負荷時における膵β細胞オートファジー機構の解析Principal Investigator
- Principal Investigator
  
  綿田裕孝
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
New insulin resistance regulatory factor "susceptibility to fat loading"
- Principal Investigator
  
  KAWAMORI Ryuzo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Molecular mechanism controlling PDX1 expression in vivo
- Principal Investigator
  
  FUJITANI Yoshio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
膵β細胞に関わる転写因子の網羅的検索-プロテオミックスの手法を用いて-
- Principal Investigator
  
  河盛隆造
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
膜4回貫通型蛋白CD9の膵ラ氏島分化及びインスリン分泌能における重要性の解明
- Principal Investigator
  
  河盛隆造
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
膵ランゲルハンス島前駆細胞の単離とそれを用いた再生療法の試みPrincipal Investigator
- Principal Investigator
  
  綿田裕孝
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
膵臓前駆細胞から膵ラ氏島前駆細胞への分化メカニズムの解明Principal Investigator
- Principal Investigator
  
  綿田裕孝
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Juntendo University
The relation between the impaired islet microcirculation and diabetes
- Principal Investigator
  
  KAWAMORI Ryuzo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  JUNTENDO UNIVERSITY
OXIDATIVE STRESS AND EXERCISE : ESTABLISHMENT OF EXERCISE THERAPY FOR HEALTH PROMOTION AND PREVENTION OF DIABETES
- Principal Investigator
  
  TANAKA Yasushi
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  JUNTENDO UNIVERSITY

[Journal Article] Monitoring autophagic flux in vivo revealed its physiological response and significance of heterogeneity in pancreatic beta cells2023
- Author(s)
  Aoyama Shuhei、Nishida Yuya、Uzawa Hirotsugu、Himuro Miwa、Kanai Akiko、Ueki Kyosei、Ito Minami、Iida Hitoshi、Tanida Isei、Miyatsuka Takeshi、Fujitani Yoshio、Matsumoto Masaki、Watada Hirotaka
- Journal Title
  
  Cell Chemical Biology
  
  Volume: - Issue: 6 Pages: 658-671.e4
- DOI
  10.1016/j.chembiol.2023.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19288, KAKENHI-PROJECT-21K16373, KAKENHI-PROJECT-22K16402, KAKENHI-PROJECT-20H03735, KAKENHI-PROJECT-20K08917, KAKENHI-PROJECT-20K21386, KAKENHI-PUBLICLY-22H04655, KAKENHI-PUBLICLY-22H04652, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-23K23870
[Journal Article] Genetic ablation of p62/SQSTM1 demonstrates little effect on pancreatic β-cell function under autophagy deficiency2022
- Author(s)
  Fukae Toshinaru、Miyatsuka Takeshi、Himuro Miwa、Wakabayashi Yuka、Iida Hitoshi、Aoyama Shuhei、Mita Tomoya、Ikeda Fuki、Haruna Hidenori、Takubo Noriyuki、Nishida Yuya、Shimizu Toshiaki、Watada Hirotaka
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 612 Pages: 99-104
- DOI
  10.1016/j.bbrc.2022.04.092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03735
[Journal Article] Spatial and transcriptional heterogeneity of pancreatic beta cell neogenesis revealed by a time-resolved reporter system2022
- Author(s)
  Sasaki Shugo、Lee Michelle Y. Y.、Wakabayashi Yuka、Suzuki Luka、Winata Helena、Himuro Miwa、Matsuoka Taka-aki、Shimomura Iichiro、Watada Hirotaka、Lynn Francis C.、Miyatsuka Takeshi
- Journal Title
  
  Diabetologia
  
  Volume: 65 Issue: 5 Pages: 811-828
- DOI
  10.1007/s00125-022-05662-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04060, KAKENHI-PROJECT-22K16395, KAKENHI-PROJECT-21K20902
[Journal Article] Cumulative autophagy insufficiency in mice leads to progression of β-cell failure2022
- Author(s)
  Suzuki L, Miyatsuka T, Himuro M, Wakabayashi Y, Osonoi S, Miura M, Katahira T, Fujitani Y, Iida H, Mizukami H, Nishida Y, Watada H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 611 Pages: 38-45
- DOI
  10.1016/j.bbrc.2022.04.040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19421, KAKENHI-PROJECT-20H03463, KAKENHI-PROJECT-20H03735
[Journal Article] Reduced muscle strength of knee extensors is a risk factor for silent lacunar infarcts among Japanese elderly people: the Bunkyo Health Study.2020
- Author(s)
  Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, Aoki S, Hattori N, Motoi Y, Shimada K, Daida H, Ishijima M, Kaneko K, Nojiri S, Kawamori R, Watada H
- Journal Title
  
  JCSM Clinical Reports
  
  Volume: 5 Issue: 3 Pages: 79-85
- DOI
  10.1002/crt2.24
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03184
[Journal Article] Cellular autophagy in α cells plays a role in the maintenance of islet architecture2019
- Author(s)
  Himuro Miwa、Miyatsuka Takeshi、Suzuki Luka、Miura Masaki、Katahira Takehiro、Goto Hiromasa、Nishida Yuya、Sasaki Shugo、Koike Masato、Shiota Chiyo、Gittes George K、Fujitani Yoshio、Watada Hirotaka
- Journal Title
  
  Journal of the Endocrine Society
  
  Volume: 3 Pages: 1979-92
- DOI
  10.1210/js.2019-00075
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04202, KAKENHI-PROJECT-16K09765, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-17K09848
[Journal Article] Normal pancreatic β-cell function in mice with <i>RIP-Cre</i>-mediated inactivation of p62/SQSTM12018
- Author(s)
  Honda A, Komiya K, Hara A, Fukunaka A, Suzuki L, Miyatsuka T, Ogihara T, Fujitani Y, Watada H.
- Journal Title
  
  Endocr J
  
  Volume: 65 Issue: 1 Pages: 83-89
- DOI
  10.1507/endocrj.EJ17-0333
- NAID
  130006321958
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09764, KAKENHI-PROJECT-16K09765, KAKENHI-PROJECT-17H04202
[Journal Article] Heterogeneity of autophagic status in pancreatic β cells under metabolic stress.2018
- Author(s)
  Kamitani M, Miyatsuka T, Miura M, Azuma K, Suzuki L, Himuro M, Katahira T, Nishida Y, Fujitani Y, Watada H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 496 Issue: 2 Pages: 328-334
- DOI
  10.1016/j.bbrc.2018.01.070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09765, KAKENHI-PROJECT-17H04202
[Journal Article] Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis2018
- Author(s)
  Osonoi Y., Mita T., Azuma K., Nakajima K., Masuyama A., Goto H., Nishida Y., Miyatsuka T., Fujitani Y., Koike M., Mitsumata M., Watada H.
- Journal Title
  
  Autophagy
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01205
[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)2016
- Author(s)
  Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R,　Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Watada H. et al.
- Journal Title
  
  Autophagy
  
  Volume: 12 Pages: 1-222
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293220
[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)2016
- Author(s)
  Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R,　Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Watada H. et al.
- Journal Title
  
  Autophagy
  
  Volume: 12 Pages: 1-222
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111518
[Journal Article] Minireview: Autophagy in pancreatic beta cells and its implication in diabetes.2015
- Author(s)
  Watada H, Fujitani Y
- Journal Title
  
  Molecular Endocrinology
  
  Volume: 29 Issue: 3 Pages: 338-348
- DOI
  10.1210/me.2014-1367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461364, KAKENHI-PUBLICLY-26111518, KAKENHI-PROJECT-26293220
[Journal Article] Human IAPP-induced pancreatic beta-cell toxicity and its regulation by autophagy2014
- Author(s)
  Shigihara N., Fukunaka A., Hara A., Komiya K., Honda A., Uchida T., Abe H., Toyofuku Y., Tamaki M., Ogihara T., Miyatsuka T., Hiddinga HJ, Sakagashira S, Koike M., Uchiyama Y., Yoshimori T., Eberhardt NL, Fujitani Y., Watada H
- Journal Title
  
  J. Clin. Invest
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23390244
[Journal Article] Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy.2014
- Author(s)
  Shigihara N, Fukunaka A, Hara A, Komiya K, Honda A, Uchida T, Abe H, Toyofuku Y, Tamaki M, Ogihara T, Miyatsuka T, Hiddinga HJ, Sakagashira S, Koike M, Uchiyama Y, Yoshimori T, Eberhardt NL, Fujitani Y, Watada H.
- Journal Title
  
  J Clin Invest.
  
  Volume: 124 Issue: 8 Pages: 3634-44
- DOI
  10.1172/jci69866
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25111002, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-25461364, KAKENHI-PROJECT-25860757, KAKENHI-PUBLICLY-26111518, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-26251020, KAKENHI-PROJECT-26293220, KAKENHI-PROJECT-26860700
[Journal Article] Increased expression of ERp57/GRP58 is protective against pancreatic beta cell death caused by autophagic failure.2014
- Author(s)
  Yamamoto E, Uchida T, Abe H, Taka H, Fujimura T, Komiya K, Hara A, Ogihara T, Fujitani Y, Ueno T, Takeda S, Watada H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 453 Pages: 19-24
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26111518
[Journal Article] Exendin-4 improves beta-cell function in autophagy-deficient beta-cells2013
- Author(s)
  Abe H, Uchida T, Hara A, Mizukami H, Komiya K, Koike M, Shigihara N, Toyofuku Y, Ogihara T, Uchiyama Y, Yagihashi S, Fujitani Y, Watada H
- Journal Title
  
  Endocrinology
  
  Volume: 154 Pages: 4512-4524
- Data Source
  KAKENHI-PROJECT-23390244
[Journal Article] 膵ss細胞の分子増殖:妊娠時の膵ss細胞2012
- Author(s)
  豊福優希子,内田豊義,綿田裕孝
- Journal Title
  
  Islet equality
  
  Volume: 1 Pages: 20-24
- Data Source
  KAKENHI-PROJECT-23659472
[Journal Article] 妊娠時の膵ss細胞機能における新知見2012
- Author(s)
  豊福優希子,内田豊義,綿田裕孝
- Journal Title
  
  Daiabetes Frontier
  
  Volume: 23 Pages: 407-412
- Data Source
  KAKENHI-PROJECT-23659472
[Journal Article] 妊娠に伴う膵ss細胞増殖のメカニズム2011
- Author(s)
  綿田裕孝,豊福優希子,内田豊義
- Journal Title
  
  Diabetes Journal:糖尿病と代謝
  
  Volume: 39 Pages: 193-199
- Data Source
  KAKENHI-PROJECT-23659472
[Journal Article] Determinants of intramyocellular lipid accumulation after dietary fat loading in non-obese men.2011
- Author(s)
  櫻井裕子、田村好史、河盛隆造、綿田裕孝
- Journal Title
  
  J Diabetes Invest
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300255
[Journal Article] セロトニンによる妊娠時の膵 ss 細胞機能・容積変化のメカニズム2011
- Author(s)
  綿田裕孝,豊福優希子,内田豊義
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 1226-1232
- Data Source
  KAKENHI-PROJECT-23659472
[Journal Article] Determinants of intramyocellular lipid accumulation after dietary fat loading in non-obese men2011
- Author(s)
  Sakurai Y, Tamura Y, Takeno K, Kumashiro N, Sato F, Kakehi S, Ikeda S, Katamoto S, Ogura Y, Saga N, Naito H, Fujitani Y, Hirose T, Kawamori R, Watada H
- Journal Title
  
  Diabetes Invest
  
  Volume: 2 Pages: 310-317
- Data Source
  KAKENHI-PROJECT-21300255
[Journal Article] Association of T2 relaxation time determined by magnetic resonance imaging and intramyocellular lipid content of the soleus muscle in healthy subjects2011
- Author(s)
  櫻井裕子、田村好史、河盛隆造、綿田裕孝
- Journal Title
  
  J Diabetes Invest
  
  Volume: 2 Issue: 5 Pages: 356-358
- DOI
  10.1111/j.2040-1124.2011.00108.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300255, KAKENHI-PROJECT-23500857
[Journal Article] 妊娠による膵 ss細胞機能、容積変化のメカニズム2011
- Author(s)
  豊福優希子,綿田裕孝
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 32 Pages: 197-203
- Data Source
  KAKENHI-PROJECT-23659472
[Journal Article] Determinants of intramyocellular lipid accumulation after dietary fat loading in non-obese men2011
- Author(s)
  櫻井裕子、田村好史、河盛隆造、綿田裕孝
- Journal Title
  
  J Diabetes Invest
  
  Volume: 2 Pages: 310-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300255
[Journal Article] Role of VEGF-A in pancreatic beta cells.2010
- Author(s)
  Watada H.
- Journal Title
  
  Endocr J.
  
  Volume: 57(3) Pages: 185-91
- NAID
  10029583836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591073
[Journal Article] Role of VEGF-A in pancreatic beta cells.2010
- Author(s)
  Watada H
- Journal Title
  
  Endocr J. 57(3)
  
  Pages: 185-91
- NAID
  10029583836
- Data Source
  KAKENHI-PROJECT-20591073
[Journal Article] Autophagy in health and disease. 4. The role of pancreatic beta-cell autophagy in health and diabetes2010
- Author(s)
  Fujitani, Y., Ueno, T., Watada, H.
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025031
[Journal Article] Impact of whole body irradiation and vascular endothelial growth factor-A on increased beta cell mass after bone marrow transplantation in a mouse model of diabetes induced by streptozotocin.2009
- Author(s)
  Nakayama S, Uchida T, Choi JB, Fujitani Y, Ogihara T, Iwashita N, Azuma K, Mochizuki H, Hirose T, Kawamori R, Inoue M, Watada H
- Journal Title
  
  Diabetologia. 52(1)
  
  Pages: 115-24
- Data Source
  KAKENHI-PROJECT-20591073
[Journal Article] Normal islet vascularization is dispensable for expansion of beta-cell mass in response to high-fat diet induced insulin resistance.2009
- Author(s)
  Toyofuku Y, Uchida T, Nakayama S, Hirose T, Kawamori R, Fujitani Y, Inoue M, Watada H
- Journal Title
  
  Biochem Biophys Res Commun. 383(3)
  
  Pages: 303-7
- Data Source
  KAKENHI-PROJECT-20591073
[Journal Article] Combined expression of transcription factors induces AR42J-B13 cells to differentiate into insulin-producing cells2008
- Author(s)
  Ogihara T, Fujitani Y, Uchida T, Kanno R, Choi JB, Hirose T, Kawamori R, Watada H
- Journal Title
  
  Endocr J 55
  
  Pages: 691-698
- NAID
  10022609145
- Data Source
  KAKENHI-PROJECT-19591067
[Journal Article] Dose-dependent requirement of patched homologue 1 in mouse pancreatic beta cell mass2008
- Author(s)
  Nakayama S, Arakawa M, Uchida T, Ogihara T, Kanno R, Ikeda F, Azuma K, Hirose T, Kawamori R, Fujitani Y, Watada H
- Journal Title
  
  Diabetologia 51
  
  Pages: 1883-1892
- Data Source
  KAKENHI-PROJECT-19591067
[Presentation] 急性巣状細菌性腎炎が疑われた1型糖尿病の一例2023
- Author(s)
  綾目達宏, 門脇聡, 持田曜弘, 舩山崇, 佐藤淳子, 後藤広昌, 池田富貴, 綿田裕孝
- Organizer
  第60回日本糖尿病学会関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-23K08018
[Presentation] 順天堂成人1型糖尿病コホート研究(Jun One Study)死亡症例の検討2023
- Author(s)
  岩本達也, 佐藤淳子,栗田実佳, 小澁真実, 中島健一, 山崎望, 小貝俊樹, 佐野里奈, 池田富貴, 麻生克己, 綿田裕孝
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K08018
[Presentation] ミニメド770Gシステム(ハイブリッドクローズドループシステム)が1型糖尿病のコントロールに与える影響の観察研究2023
- Author(s)
  小貝俊樹, 佐藤淳子, 栗田実佳, 小澁真実, 常見亜佐子, 山崎望, 岩本達也, 池田恒基, 佐野里奈, 池田富貴, 成瀬明日華, 平野直美, 綿田裕孝
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K08018
[Presentation] Identification of Novel Compounds That Regulate Autophagy Flux and Their Application to Drug Discovery2022
- Author(s)
  Minami Ito, Yuya Nishida, Shuhei Aoyama, Hirotsugu Uzawa, Tastuya Iwamoto, Akiko Kanai, Kyosei Ueki, Hirotatsu Kojima, Hirotaka Watada
- Organizer
  The 10th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19515
[Presentation] Reduced insulin sensitivity and muscle strength are independent risk factors for silent lacunar infarcts and synergistically increase the risk among japanese elderly people: the bunkyo health study.2020
- Author(s)
  Someya Y, Tamura Y, Kaga H, Sugimoto D, Kadowaki S, Suzuki R, Kawamori R, Watada H.
- Organizer
  80th American Diabetes Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03184
[Presentation] 下肢伸展筋力と無症候性ラクナ梗塞の関連：Bunkyo Health Study.2020
- Author(s)
  染谷由希, 田村好史, 加賀英義, 青木茂樹, 服部信孝, 本井ゆみ子, 島田和典, 代田浩之, 河盛隆造, 綿田裕孝.
- Organizer
  第62回日本老年医学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03184
[Presentation] 都市部在住高齢者におけるサルコペニア肥満と認知機能低下の関連：Bunkyo Health Study.2020
- Author(s)
  染谷由希, 田村好史, 加賀英義, 青木茂樹, 服部信孝, 本井ゆみ子, 島田和典, 代田浩之, 河盛隆造, 綿田裕孝.
- Organizer
  第7回日本サルコペニア・フレイル学会大会
- Data Source
  KAKENHI-PROJECT-18H03184
[Presentation] Autophagy Deficiency Cumulatively Causes β-Cell Failure in Mice2019
- Author(s)
  Suzuki, L., Miyatsuka, T., Himuro, M., Miura, M., Katahira, T., Komiya, K., Fujitani, Y., Nishida, Y.,Watada, H.
- Organizer
  79th American Diabetes Association, San Francisco(USA), 2019.6.7-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04202
[Presentation] Exploring the Role of Autophagy in Pancreatic Alpha Cells2019
- Author(s)
  Himuro, M., Miyatsuka, T., Suzuki, L., Miura, M., Katahira, T., Goto, H., Nishida, Y., Sasaki, S., Fujitani, Y.,Watada, H.
- Organizer
  79th American Diabetes Association, San Francisco(USA), 2019.6.7-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04202
[Presentation] Autophagy Deficiency Cumulatively Causes β-Cell Failure in Mice2019
- Author(s)
  Suzuki L., Miyatsuka T., Himuro M., Miura M., Katahira T., Komiya K., Fujitani Y., Nishida Y., Watada H.
- Organizer
  79th American Diabetes Association Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09849
[Presentation] 膵β細胞における時期特異的オートファジー不全モデルマウスの作製とその機能解析2019
- Author(s)
  鈴木路可, 宮塚健, 氷室美和, 三浦正樹, 片平雄大, 三田智也, 小宮幸次, 西田友哉, 藤谷与士夫, 綿田裕孝
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09849
[Presentation] Role of autophagy in pancreatic beta cells and atherosclerosis2018
- Author(s)
  Watada H.
- Organizer
  The 4th IMCR Symposium on Endocrine and Metabolim: At the Cutting Edge of Metabolic Regulation Research Gunmaken
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04202
[Presentation] 膵β細胞における時間特異的Atg7欠損マウスの作製と機能解析2017
- Author(s)
  鈴木路可, 宮塚健, 氷室美和, 神谷麻衣, 三浦正樹, 小宮幸次, 藤谷与士夫, 西田友哉, 綿田裕孝
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04202
[Presentation] Cumulative autophagy deficiency causes progressive β-cell failure.2017
- Author(s)
  Suzuki L., Miyatsuka T., Himuro M., Miura M., Fujitani Y., Nishida Y., Watada H.
- Organizer
  The 8th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04202
[Presentation] Defect of autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis2017
- Author(s)
  Osonoi Y., Mita T., Azuma K., Nakajima K., Masuyama A., Nishida Y., Miyatsuka T., Fujitani Y., Koike M., Mitsumata M., Watada H.
- Organizer
  The 8th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01205
[Presentation] Exploring the autophagy mechanism in pancreatic alpha cell2017
- Author(s)
  Himuro M., Miyatsuka T., Suzuki L., Koike M., Shiota C., Gittes G. K., Fujitani Y., Watada H.
- Organizer
  53rd Annual meeting of the European Association for the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04202
[Presentation] 膵α細胞特異的オートファジー不全モデルマウスの作成とその機能解析2017
- Author(s)
  氷室美和, 宮塚健, 鈴木路可, 神谷麻衣, 三浦正樹, 片平雄大, 小池正人, Shiota C., Gittes G. K., 藤谷与士夫, 綿田裕孝
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04202
[Presentation] 膵β細胞特異的オートファジー欠損マウスにおいて, エキセナチドは耐糖能と膵β細胞機能を改善する2013
- Author(s)
  阿部浩子, 内田豊義, 原朱美, 水上浩哉, 小宮幸次, 小池正人, 内山安男, 八木橋操六, 藤谷与士夫, 綿田裕孝
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  宮城県(日本)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] ERp57はオートファジー不全に伴う膵β細胞障害に保護的に作用する2013
- Author(s)
  山本恵理子, 内田豊義, 阿部浩子, 小宮幸次, 原朱美, 荻原健, 武田省, 藤谷与士夫, 綿田裕孝
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本県(日本)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] ERp57 protects autophagy deficient beta-cells from cellular damage2013
- Author(s)
  Yamamoto E, Uchida T, Abe H, Komiya K, Hara A, Ogihara T, Takeda S, Fujitani Y, Watada H
- Organizer
  American Diabetes Association 73rd Scientific Sessions
- Place of Presentation
  Chicago (America)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] Exendin-4 treatment improves glucose and beta-cell function of beta-cell-specific autophagy deficient mice2012
- Author(s)
  Abe H, Uchida T, Komiya K, Shigihara N, Toyofuku Y, Hara A, Hirose T, Fujitani Y, Watada H
- Organizer
  American Diabetes Association 72nd Scientific Sessions
- Place of Presentation
  Philadelphia (America)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] 膵β細胞特異的オートファジー欠損マウスにおいて, エキセナチドは耐糖能と膵β細胞機能を改善する2012
- Author(s)
  阿部浩子, 内田豊義, 小宮幸次, 鴫原奈弓, 豊福優希子, 原朱美, 弘世貴久, 藤谷与士夫, 綿田裕孝
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  神奈川県(日本)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] 膵β細胞におけるオートファジーの意義2012
- Author(s)
  綿田裕孝
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  愛知県(日本)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] 膵β細胞特異的Atg7欠損マウスに対するExenatide作用の検討2011
- Author(s)
  阿部浩子, 内田豊義, 鴫原奈弓, 小宮幸次, 豊福優希子, 弘世貴久, 藤谷与士夫, 綿田裕孝
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道(日本)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] Changes in intramyocellular lipid accumulation and Insulin sensitivity after High-Fat Loading are associated with transcriptional response in human skeletal muscle2011
- Author(s)
  Kakehi S, Tamura Y, Kawamori R, Watada H., et al
- Organizer
  American Diabetes Association 71st scientific sessions
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Autophagy in the beta cells2011
- Author(s)
  Watada H
- Organizer
  The 16th Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  Tokyo (Japan)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] Autophagy and Quality Control in the Beta CellQuality Control in the Beta Cell. Nutrient Control over Autophagy in the Beta Cell2011
- Author(s)
  Watada H
- Organizer
  American Diabetes Association 71st scientific sessions
- Place of Presentation
  San Diego (America)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] 膵β細胞において, 遊離脂肪酸投与による急性期のオートファジー活性化は小胞体ストレスを介さずに誘導される2011
- Author(s)
  小宮幸次, 内田豊義, 阿部浩子, 田蒔基行, 河盛隆造, 弘世貴久, 藤谷与士夫, 綿田裕孝
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道(日本)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] 膵β細胞における遊離脂肪酸誘導性オートファジーのメカニズム解析2011
- Author(s)
  小宮幸次, 内田豊義, 阿部浩子, 河盛隆造, 藤谷与士夫 , 綿田裕孝
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  兵庫県(日本)
- Data Source
  KAKENHI-PROJECT-23390244
[Presentation] Intramyocellular lipid accumulation and insulin sensitivity2010
- Author(s)
  田村好史、綿田裕孝、河盛隆造
- Organizer
  日本農芸化学会
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Autophagy in pancreatic beta cells.2010
- Author(s)
  Watada H
- Organizer
  14th International Congress of Endocrinology (ICE 2010)
- Place of Presentation
  Kyoto (Japan)
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PUBLICLY-21025031
[Presentation] Susceptible Factors for Intramyocellular Lipid Accumulation by Dietary Fat Loading in Non-Obese Men.2010
- Author(s)
  櫻井裕子、田村好史、河盛隆造、綿田裕孝
- Organizer
  American Diabetes Association 70^<th> Scientific sessions
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Intramyocellular lipid accumulation and insulin sensitivity2010
- Author(s)
  田村好史, 綿田裕孝, 河盛隆造, 他
- Organizer
  日本農芸化学会
- Place of Presentation
  東京
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Susceptible Factors for Intramyocellular Lipid Accumulation by Dietary Fat Loading in Non-Obese Men2010
- Author(s)
  櫻井裕子、田村好史、河盛隆造、綿田裕孝
- Organizer
  American Diabetes Association 70^<th> Scientific sessions
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] 肝、骨格筋の糖取り込みの評価法と細胞内脂質蓄積との関連性2009
- Author(s)
  田村好史、綿田裕孝、河盛隆造
- Organizer
  第43回糖尿病学の進歩
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-19300232
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発生に与える影響とその規定因子2009
- Author(s)
  櫻井裕子、田村好史、綿田裕孝、河盛隆造
- Organizer
  第52回日本糖尿病学会年次学術集会
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Anatomic and functional imaging of the body2009
- Author(s)
  田村好史, 綿田裕孝, 河盛隆造, 他
- Organizer
  日米医学協力研究会合同会議
- Place of Presentation
  Baton Rouge, USA
- Year and Date
  2009-11-09
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Diabetes and Exercise : Intramycellular Lipid Accumulation and Insulin Sensitivity2009
- Author(s)
  田村好史, 綿田裕孝, 河盛隆造, 他
- Organizer
  The 15th Korea-Japan Symposium on Diabetes Mellitus
- Place of Presentation
  Jeju, Korea
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Anatomic and functional imaging of the body2009
- Author(s)
  田村好史、綿田裕孝、河盛隆造
- Organizer
  日米医学協力研究会合同会議
- Year and Date
  2009-11-09
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発生に与える影響とその規定因子2009
- Author(s)
  櫻井裕子, 田村好史, 綿田裕孝, 河盛隆造, 他
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発生に与える影響とその規定因子2009
- Author(s)
  田村好史、綿田裕孝、河盛隆造
- Organizer
  第64回日本体力医学会
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発生に与える影響とその規定因子2009
- Author(s)
  田村好史、綿田裕孝、河盛隆造
- Organizer
  第59回日本体質医学会
- Year and Date
  2009-07-26
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発生に与える影響とその規定因子2009
- Author(s)
  櫻井裕子, 田村好史, 竹野景海, 熊代尚記, 池田真一, 筧佐織, 綿田裕孝, 河盛隆造
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19300232
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発生に与える影響とその規定因子2009
- Author(s)
  田村好史, 綿田裕孝, 河盛隆造, 他
- Organizer
  第64回日本体力医学会
- Place of Presentation
  新潟
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Diabetes and Exercise : Intramycellular Lipid Accumulation and Insulin Sensitivity2009
- Author(s)
  田村好史、綿田裕孝、河盛隆造
- Organizer
  The 15th Korea-Japan Symposium on Diabetes Mellitus
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発生に与える影響とその規定因子2009
- Author(s)
  田村好史, 綿田裕孝, 河盛隆造, 他
- Organizer
  第59回日本体質医学会
- Place of Presentation
  東京・学士会館
- Year and Date
  2009-07-26
- Data Source
  KAKENHI-PROJECT-21300255
[Presentation] Effect of Hedgehog Signal Intensity on pancreas Morphogenesis2007
- Author(s)
  Nakayama S, Watada H, Fujitani Y, Igarashi Y, Iwashita N, Ikeda F, Kanno R, Uchida T, Ogihara T, Motoyama J and Kawamori R
- Organizer
  American Diabetes Association's 67th Scientific sessions
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-19591067

1. KAWAMORI Ryuzo (00116021)

# of Collaborated Projects: 9 results

# of Collaborated Products: 25 results
2. Miyatsuka Takeshi (60622363)

# of Collaborated Projects: 9 results

# of Collaborated Products: 11 results
3. FUJITANI Yoshio (30433783)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
4. 西田友哉 (10581449)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
5. TANAKA Yasuhi (40276499)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TAMURA Yoshifumi (80420834)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
7. Ikeda Fuki (80445494)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. 多田昇弘 (50338315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TOYOFUKU Yukiko (70598078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. INOUE Masahiro (10342990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HASHIZUME Hiroya (90261289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAKAI Ken (70333044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MAEDA Shiro (50314159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KATAMOTO Shizuo (50053343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KANAZAWA Akio (30407259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Goto Hiromasa (90622746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Komiya Koji (50385077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 柳田光昭 (80365569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 三田智也 (90532557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 染谷由希 (10597090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. 加賀英義 (90814757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
22. 小松雅明 (90356254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 笹澤有紀子 (20594922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 野田展生 (40396297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 中戸川仁 (90414010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 安藤美樹 (10424251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 服部信孝 (80218510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 洲崎悦生 (10444803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 日置寛之 (00402850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 松本雅記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 吉森保

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WATADA Hirotaka 綿田 裕孝

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Mechanisms of autophagy regulation and its disruption in pancreatic beta cellsPrincipal Investigator

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Pathophysiology of pancreatic beta cell insufficiency using a novel in vivo gene screening methodPrincipal Investigator

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Discovery of new anti-diabetic drugs activating autophagy in beta cellsPrincipal Investigator

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Molecular Mechanism of beta cell failure due to autophagic failurePrincipal Investigator

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Autophagic failure in isletsPrincipal Investigator

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Autophagic failure of smooth muscle cellsPrincipal Investigator

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WATADA Hirotaka 綿田裕孝