YUKI Yoshikazu 幸義和

Researcher Number	60345030
Other IDs	https://orcid.org/0000-0001-6574-9184
Affiliation (based on the past Project Information) *help	2017 – 2019: 東京大学, 医科学研究所, 特任研究員 2009 – 2014: The University of Tokyo, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Virology / Applied pharmacology Except Principal Investigator Bacteriology (including mycology) / Immunology
Keywords	Principal Investigator ワクチン / 薬学 / 免疫学 / バイオテクノロジー / 医療福祉 / ドラックデリバリー / RNAi / コメ / 経口蛋白医薬 / ドラッグデリバリー / オルガネラ工学 … More Except Principal Investigator … More 感染症 / 結核ワクチン / ドラッグデリバリーシステム / 粘膜免疫応答 / 経鼻ワクチン / カチオン化ナノゲル / フコシル化 / UEA-1 / 粘膜免疫 / 共生細菌 / 抗原取り込み / 上皮細胞 / M細胞 / 粘膜免役 Less

Basic research for the TB vaccine development based on the novel drug delivery system.
- Principal Investigator
  
  Nakahashi Rika
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  The University of Tokyo
New attempt of cold-chain free oral influenza vaccine developmentPrincipal Investigator
- Principal Investigator
  
  YUKI Yoshikazu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Development of cold - chain free oral protein-based drugPrincipal Investigator
- Principal Investigator
  
  YOSHIKAZU Yuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Applied pharmacology
- Research Institution
  The University of Tokyo
Analysis of antigen-uptake network at mucosal epithelial layer
- Principal Investigator
  
  KIYONO Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo

All 2020 2019 2018 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book Patent

[Book] 注射剤・経口製剤に代る新しい薬剤投与ヂバイスの開発―2014
- Author(s)
  幸　義和
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-24659203
[Book] 粘膜ワクチン製剤のＤＤＳ技術の動向と実用化の可能性―2013
- Author(s)
  幸　義和
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-24659203
[Book] ワクチンのDDS技術の開発動向―経鼻投与技術動向―　「ワクチンの市場動向と開発・製造実務集」2012
- Author(s)
  幸　義和ら　多数
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-24659203
[Book] ワクチンのDDS技術の開発動向-経鼻投与技術動向- 「ワクチンの市場動向と開発・製造実務集」2012
- Author(s)
  幸義和
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-21200073
[Book] ワクチンのDDS技術の開発動向-経口投与技術動向- 「ワクチンの市場動向と開発・製造実務集」2012
- Author(s)
  幸義和
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-21200073
[Book] ワクチンの市場動向と開発・製造実務集2012
- Author(s)
  幸義和, ら多数
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-21200073
[Book] 臨床粘膜免疫学(経口ワクチン、p532-539)2010
- Author(s)
  幸義和(清野宏編)
- Total Pages
  722
- Publisher
  (株)シナジー
- Data Source
  KAKENHI-PROJECT-21200073
[Book] Allergy Frontiers : Future Perspectives(Transgenic Rice)2009
- Author(s)
  Y.Yuki, F.Takaiwa, H.Kiyono
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] A role for the CCR5?CCL5 interaction in the preferential migration of HSV-2-specific effector cells to the vaginal mucosa upon nasal immunization2019
- Author(s)
  Joo Sunyi、Suwanto Aldina、Sato Ayuko、Nakahashi-Ouchida Rika、Mori Hiromi、Uchida Yohei、Sato Shintaro、Kurashima Yosuke、Yuki Yoshikazu、Fujihashi Kohtaro、Kawaguchi Yasushi、Kiyono Hiroshi
- Journal Title
  
  Mucosal Immunology
  
  Volume: 12 Issue: 6 Pages: 1391-1403
- DOI
  10.1038/s41385-019-0203-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22524, KAKENHI-PROJECT-19K22532, KAKENHI-PROJECT-19K22634, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06433, KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-17H04080, KAKENHI-PROJECT-18KK0432, KAKENHI-PROJECT-18H05280, KAKENHI-PROJECT-19H03450, KAKENHI-PROJECT-17K08821
[Journal Article] Nanogel-based nasal vaccines for infectious and lifestyle-related diseases.2019
- Author(s)
  Azegami T, Yuki Y, Nakahashi R, Itoh H, Kiyono H.
- Journal Title
  
  Molecular Immunology
  
  Volume: 98 Pages: 19-24
- DOI
  10.1016/j.molimm.2017.10.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08821
[Journal Article] ナノゲルデリバリーシステムによる肺炎球菌経鼻ワクチンの開発2019
- Author(s)
  中橋理佳、幸義和、清野宏
- Journal Title
  
  炎症と免疫
  
  Volume: 27 Pages: 19-24
- Data Source
  KAKENHI-PROJECT-17K08821
[Journal Article] 粘膜ワクチンの潮流と課題2018
- Author(s)
  西村潤、中橋理佳、幸義和、清野宏
- Journal Title
  
  医学のあゆみ
  
  Volume: 264 Pages: 18227-18234
- Data Source
  KAKENHI-PROJECT-17K08821
[Journal Article] Cationic pullulan nanogel as a safe and effective nasal vaccine delivery system for respiratory infectious diseases.2018
- Author(s)
  Nakahashi-Ouchida R., Yuki Y., Kiyono H.
- Journal Title
  
  Human Vaccines & Immunotherapeutics
  
  Volume: 14 Issue: 12 Pages: 2189-2193
- DOI
  10.1080/14760584.2017.1395702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08821
[Journal Article] Novel transgenic rice-based vaccines.2015
- Author(s)
  Azegami, T., Itoh, H., Kiyono, H. and Yuki, Y.
- Journal Title
  
  Arch. Immunol. Ther. Exp.
  
  Volume: 63(2) Issue: 2 Pages: 87-99
- DOI
  10.1007/s00005-014-0303-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203
[Journal Article] Comparative whole-genome analyses of selection marker‐free rice-based cholera toxin B-subunit vaccine lines and wild-type lines.2015
- Author(s)
  Kashima, K., Mejima, M., Kurokawa, S., Kuroda, M., Kiyono, H. and Yuki, Y.
- Journal Title
  
  BMC Genomics
  
  Volume: 48 Issue: 1 Pages: 48-48
- DOI
  10.1186/s12864-015-1285-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203
[Journal Article] Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques.2015
- Author(s)
  Fukuyama, Y., Yuki, Y., Katakai, Y., Harada, N., Takahashi, H., Takeda, S., Mejima, M., Joo, S., Kurokawa, S., Sawada, S., Shibata, H., Park, EJ., Fujihashi., K, Briles, D., Yasutomi, Y., Tsukada, H., Akiyoshi, K., Kiyono, H.
- Journal Title
  
  Mucosal Immunol.
  
  Volume: - Issue: 5 Pages: 1144-1153
- DOI
  10.1038/mi.2015.5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203, KAKENHI-PROJECT-25670225
[Journal Article] Determination of genomic location and structure of the transgenes in marker-free rice-based cholera vaccine by using whole genome resequencing approach.2015
- Author(s)
  Mejima, M., Kashima, K., Kuroda, M., Takeyama, N., Kurokawa S., Fukuyama Y., Kiyono H., Itoh, K., Mitsui, T., and Yuki, Y.
- Journal Title
  
  Plant Cell Tiss. Organ Cult.
  
  Volume: 120 Issue: 1 Pages: 35-48
- DOI
  10.1007/s11240-014-0575-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203
[Journal Article] A rice-based soluble form of a murine TNF-specific ll ama variable domain of heavy-chain antibody suppresses collagen-induced arthr itis in mice.2014
- Author(s)
  M. Abe, Y. Yuki*, S. Kurokawa et.al.
- Journal Title
  
  J. Biotechnol.
  
  Volume: 175 Pages: 45-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659203
[Journal Article] Specific expression of apolipoprotein A-IV in the follicle-associated epithelium of the small intestine.2014
- Author(s)
  Tokuhara, D., Nochi, T., Matsumura, A., Mejima, M., Takahashi, Y., Kurokawa, S., Kiyono, H. and Yuki Y.
- Journal Title
  
  Dig. Dis. Sci.
  
  Volume: 59 Issue: 11 Pages: 2682-2692
- DOI
  10.1007/s10620-014-3203-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203, KAKENHI-PROJECT-26660245
[Journal Article] RNAi-mediated suppression of endogenous storage proteins leadsto a change in localization of overexpressed cholera toxinB-subunit and the allergen protein RAG2 in rice seeds.2014
- Author(s)
  Kurokawa, S., et al.
- Journal Title
  
  Plant Cell Rep.
  
  Volume: 33 Issue: 1 Pages: 75-87
- DOI
  10.1007/s00299-013-1513-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24590171, KAKENHI-PROJECT-24658097, KAKENHI-PROJECT-24659203
[Journal Article] Induction of toxin-specific neutralizing immunity by molecularly uniform rice-based oral cholera toxin B subunit vaccine without plant-associated sugar modification.2013
- Author(s)
  Yuki, Y., et al.
- Journal Title
  
  Plant Biotechnol. J.
  
  Volume: 11 Issue: 7 Pages: 799-808
- DOI
  10.1111/pbi.12071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-24658097, KAKENHI-PROJECT-24659203
[Journal Article] Rice-based oral antibody fragment prophylaxis and therapy against rotavirus infection.2013
- Author(s)
  Tokuhara, D., et al.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 123 Issue: 9 Pages: 3829-3838
- DOI
  10.1172/jci70266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-24659203
[Journal Article] Figihashi. Potential roles of CCR5+CCR6+ dendric cells induced by nasal ovalbumin plus Flt3 ligand expressing adnovirus for mucosal IgA responses2013
- Author(s)
  Y. Fukiyama, D. Tokuhara, S. Sekine, K. Aso, K. Kataoka, J. Davydova, M. Yamamoto, RS Gilbert, Y. Tokuhara, K. Fujihashi, J. Kunisawa, Y. Yuki, H. Kiyono, JR McGhee, K
- Journal Title
  
  PloS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Nanogel-Based PspA Intranasal Vaccine Prevents Invasive Disease and Nasal colnization by Streptococcus pneumoniae2013
- Author(s)
  IG. Kong, A. Sato, Y. Yuki, et.al.
- Journal Title
  
  Infection and Immunity
  
  Volume: 81 Pages: 1825-1634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659203
[Journal Article] Induction of Toxin-specific Neutralizing Immunity by Molecularly Uniform Rice-based Oral Cholera Toxin B Subunit Vaccine without Plant-associated Sugar Modification2013
- Author(s)
  Y. Yuki, M. Mejima, S. Kurokawa, T. Hiroiwa, Y. Takahashi, D. Tokuhara, T. Nochi, Y. Katakai, M. Kuroda, N. Takeyama, K. Kashima, M. Abe, Y. Chen, U. Nakanishi, T. Masumura, Y. Takeuchi, H. Kozuka-Hata, H. Shibata, M. Oyam|, K. Tanaka, H. Kiyono
- Journal Title
  
  Plant Biotechnol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] MucoRice-cholera toxin B-subunit, a rice-based oral cholera vaccine, down-regulates the expression of α-amylase/trypsin inhibitor-like protein family as major rice allergens.2013
- Author(s)
  Kurokawa, S., et al.
- Journal Title
  
  J. Proteome Res.
  
  Volume: 12 Issue: 7 Pages: 3372-3382
- DOI
  10.1021/pr4002146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-24590171, KAKENHI-PROJECT-24658097, KAKENHI-PROJECT-24659203
[Journal Article] Nanogel-based PspA intranasal vaccine prevents invasive disease and nasal colonization by Pneumococcus2013
- Author(s)
  IG. Kong, A. Sato, Y. Yuki, T. Nochi, H. Takahashi, S. Sawada, M. Mejima, S. Kurokawa, K. Okada, S. Sato, D. Briles, J. Kunisawa, Y. Inoue, M. Yamamoto, K. Akiyoshi, and H. Kiyono
- Journal Title
  
  Infect. & Immun
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] RNAi suppression of rice endogenous storage proteins enhances the production of rice-based Botulinum neutrotoxin type A vaccine2012
- Author(s)
  Y. Yuki, M. Mejima, S. Kurokawa, et.al.
- Journal Title
  
  Vaccine
  
  Volume: 30 Pages: 4160-4166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659203
[Journal Article] Transcription factor Spi-B–dependent and –independentpathways for the development of Peyer’s patch M cells.2012
- Author(s)
  S. Sato, S. Kaneto, N. Shibata, Y. Takahashi, H. Okura, J. Kunisawa,, Y. Yuki and H.Kiyono
- Journal Title
  
  Mucosal Immunol
  
  Volume: Dec 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659203
[Journal Article] Transcription factor Spi-B-dependent and -independentpathways for the development of Peyer's patch M cells2012
- Author(s)
  S. Sato, S. Kaneto, N. Shibata, Y. Takahashi, H. Okura, Y. Yuki, J. Kunisawaand H. Kiyono
- Journal Title
  
  Mucosal Immunol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Transcription factor Spi-B-dependent and -independentpathways for the development of Peyer' s patch M cells.2012
- Author(s)
  S. Sato, S. Kaneto, N. Shibata, Y. Takahashi, H. Okura, Y. Yuki., et. al.
- Journal Title
  
  Mucosal Immunol.
  
  Volume: Dec. 5(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] RNAi suppression of rice endogenous storage proteins enhances the production of rice-based Botulinum neutrotoxin type A vaccine2012
- Author(s)
  Y. Yuki, M. Mejima, S. Kurokawa, T. Hiroiwa, IG. Kong, M. Kuroda, Y. Takahashi, T. Nochi, D. Tokuhara, T. Kohda, S. Kozaki, H. Kiyono
- Journal Title
  
  Vaccine
  
  Volume: 30 Pages: 4160-4166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Novel vaccine development strategies for inducing mucosal immunity2012
- Author(s)
  Fujkuyama Y, Tokuhara D, Kataoka K, Gilbert RS, McGhee JR, Yuki Y, Kiyono H, Fujihashi K
- Journal Title
  
  Expert Rev. Vaccines
  
  Volume: 11 Pages: 376-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress2011
- Author(s)
  K. Terahara, T. Nochi, M. Yoshida, Y. Takahashi, Y. Goto, H. Hatai, S. Kurokawa, M-H. Jang, M-N. Kweon, SE. Domino, T. Hiroi, Y. Yuki, Y. Tsunetsugu-Yokota, K. Kobayashi, H. Kiyono
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 404 Pages: 822-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress.2011
- Author(s)
  Terahara K, Nochi T, Yoshida M, Takahashi Y, Goto Y, Hatai H, Kurokawa S, Jang MH, Kweon MN, Domino SE, Hiroi T, Yuki Y, Tsunetsugu-Yokota Y, Kobayashi K, Kiyono H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 404 Pages: 822-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] Secretory IgA-mediated protection against V.cholerae and heat-labileenterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine.2010
- Author(s)
  Tokuhara D, Yuki Y, Nochi T, Kodama T, Mejima M, Kurokawa S, Takahashi Y, Nanno M, Nakanishi U, Takaiwa F, Honda T, Kiyono H.
- Journal Title
  
  Proc Natl Acad Sci USA.
  
  Volume: 107 Pages: 8794-8799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] Secretory IgA-mediated protection against V. cholerae and heat-labile enterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine2010
- Author(s)
  D. Tokuhara, Y. Yuki, T. Nochi, T. Kodama, M. Mejima, S. Kurokawa, Y. Takahashi, M. Nanno, U. Nakanishi, F. Takaiwa, T. Honda, H. Kiyono
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Pages: 8794-8799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] In vivo molecular imaging analysis of a nasal vaccine that induces protective immunity against botulism in non-human primates2010
- Author(s)
  Y. Yuki, T. Nochi, N. Harada, Y. Katakai, H. Shibata, M. Mejima, T. Kohda, D. Tokuhara, S. Kurokawa, Y. Takahashi, F. Ono, S. Kozaki, K. Terao, H. Tsukada, H. Kiyono
- Journal Title
  
  J. Immunol
  
  Volume: 185 Pages: 5436-5443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Antigen-sampling cells in the salmonid intestinal epithelium.2010
- Author(s)
  Fuglem B, Jirillo E, Bjerkas I, Kiyono H, Nochi T, Yuki Y, Raida M, Fischer U, Koppang EO.
- Journal Title
  
  Dev Comp Immunol.
  
  Volume: 34 Pages: 768-774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines2010
- Author(s)
  T. Nochi, Y. Yuki, H. Takahashi, S. Sawada, M. Mejima, T. Kohda, N. Harada, IG. Kong, A. Sato, N. Kataoka, D. Tokuhara, S. Kurokawa, Y. Takahashi, H. Tsukada, S. Kozaki, K. Akiyoshi, H. Kiyono
- Journal Title
  
  Nat. Materials
  
  Volume: 9 Pages: 572-578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines.2010
- Author(s)
  Nochi T, Yuki Y, et al.
- Journal Title
  
  Nat.Mater.
  
  Volume: 9 Pages: 572-578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] In vivo molecular imaging analysis of a nasal vaccine that induces protective immunity against botulism in nonhuman primates.2010
- Author(s)
  Yuki Y., et al.
- Journal Title
  
  J Immunol. 185
  
  Pages: 5436-5443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] In vivo molecular imaging analysis of a nasal vaccine that induces protective immunity against botulism in nonhuman primates.2010
- Author(s)
  Yuki Y, Nochi T, Harada N, Katakai Y, Shibata H, Mejima M, Kohda T, Tokuhara D, Kurokawa S, Takahashi Y, Ono F, Kozaki S, Terao K, Tsukada H, Kiyono H.
- Journal Title
  
  JImmunol.
  
  Volume: 185 Pages: 5436-5443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] In vivo molecular imaging analysis of a nasal vaccine that induces protective immunity against botulism in non-human primates.2010
- Author(s)
  Yuki Y, Nochi T, et al.
- Journal Title
  
  J.Immunol.
  
  Volume: 185 Pages: 5436-5443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines.2010
- Author(s)
  Nochi T, Yuki Y, Takahashi H, Sawada S, Mejima M, Kohda T, Harada N, Kong IG, Sato A, Kataoka N, Tokuhara D, Kurokawa S, Takahashi Y, Tsukada H, Kozaki S, Akiyoshi K, Kiyono H.
- Journal Title
  
  Nat Mater.
  
  Volume: 9 Pages: 572-578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] Secretory IgA-mediated protection against V.cholerae and heat-labile enterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine.2010
- Author(s)
  D.Tokuhara, Y.Yuki, et al
- Journal Title
  
  Proc.Natl.Acad.Sci.USA.
  
  Volume: 107 Pages: 8794-8799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis2010
- Author(s)
  T. Obata, Y. Goto, J. Kunisawa, S. Sato, M. Sakamoto, H. Setoyama, T. Matsuki, K. Nonaka, N. Shibata, M. Gohda, Y. Kagiyama, T. Nochi, Y. Yuki, Y. Fukuyama, A. Mukai, S. Shinzaki, K. Fujihashi, C. Sasakawa, H. Iijima, M. Goto, Y. Umesaki, Y. Benno, H. Kiyono
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Pages: 7419-7424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Indigenous opportunistic bacteria inhabit mammalian gut-associatedlymphoid tissues and share a mucosal antibody-mediated symbiosis.2010
- Author(s)
  Obata T, Goto Y, Kunisawa J, Sato S, Sakamoto M, Setoyama H, Matsuki T, Nonaka K, Shibata N, Gohda M, Kagiyama Y, Nochi T, Yuki Y, Fukuyama Y, Mukai A, Shinzaki S, Fujihashi K, Sasakawa C, Iijima H, Goto M, Umesaki Y, Benno Y, Kiyono H.
- Journal Title
  
  Proc Natl Acad Sci USA.
  
  Volume: 107 Pages: 7419-7424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] A rice-based oral cholera vaccine induces macaque-specific systemic neutralizing Abs but does not influence pre-existing intestinal immunity2009
- Author(s)
  Nochi, T., Yuki, Y., et.al.
- Journal Title
  
  J.Immunol. 183
  
  Pages: 6538-6544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Oral MucoRice expressing double-mutant cholera toxin A and B subunits induces toxin-specific neutralizing immunity2009
- Author(s)
  Yuki, Y., Tokuhara, D., et.al.
- Journal Title
  
  Vaccine 27
  
  Pages: 5982-5988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200073
[Journal Article] Mucosal vaccines : novel advances in technology and delivery.2009
- Author(s)
  Yuki, Y., Kiyono, H.
- Journal Title
  
  Expert Rev Vaccines. 8
  
  Pages: 1083-1097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] Nasal Vaccination with the 40-Kilodalton outer membrane protein of Porphyromonas gingivalis and a nontoxic chimeric enterotoxin adjuvant induces lomg-term protective immunity with reduced levels of immunoglobulin E antibodies.2008
- Author(s)
  Momoi, F., Hashizume, T., Kurita-Ochiai, T., Yuki, Y., Kiyono, H ., and Yamamoto, M.
- Journal Title
  
  Infect Immun. 76
  
  Pages: 7840-7846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] Comprehensive gene expression analysis among peyer's patch M cells, villous M cells and intestinal epithelial cells by DNA microarray analysis.2008
- Author(s)
  Terahara, T., Igarashi, O., Yoshid a, M., Nochi, T., Kurokawa, S.,Takayama, N., Yuki, Y., Low, A W. and Kiyono, H.
- Journal Title
  
  J. Immunol. 180
  
  Pages: 7840-7846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249028
[Journal Article] Novel vaccine development strategies for inducing mucosal immunity
- Author(s)
  Fujkuyama Y, Tokuhara D, Kataoka K, Gilbert RS, McGhee JR, Yuki Y, et al.
- Journal Title
  
  Expert Rev. Vaccines
  
  Volume: 11 Pages: 367-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659203
[Patent] 肺炎球菌表層タンパク質2020
- Inventor(s)
  幸義和・中橋理佳・清野宏
- Industrial Property Rights Holder
  幸義和・中橋理佳・清野宏
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-17K08821
[Patent] 細胞性免疫を誘導する経鼻ワクチン2019
- Inventor(s)
  幸義和・中橋理佳・清野宏
- Industrial Property Rights Holder
  幸義和・中橋理佳・清野宏
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K08821
[Patent] 細胞性免疫を誘導する経鼻ワクチン2018
- Inventor(s)
  清野宏、中橋理佳、幸義和
- Industrial Property Rights Holder
  清野宏、中橋理佳、幸義和
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-014651
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K08821
[Patent] 肺炎球菌経鼻ワクチン2014
- Inventor(s)
  幸義和、清野宏、澤田晋一、秋吉一成
- Industrial Property Rights Holder
  東京大学ＴＬＯ
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-027205
- Filing Date
  2014-02-17
- Data Source
  KAKENHI-PROJECT-24659203
[Patent] 特許2010
- Inventor(s)
  幸義和、徳原大介、清野宏
- Industrial Property Rights Holder
  東大TLO
- Industrial Property Number
  2010-162630
- Filing Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-21200073
[Patent] ナノ抗体を発現するトランスジェニックイネ2010
- Inventor(s)
  幸義和、徳原大介、清野宏
- Industrial Property Rights Holder
  東京大学TLO
- Industrial Property Number
  2010-162630
- Filing Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Heat tolerance evaluation of the rice type oral cholera vaccine, MucoRice-CTB, for a clinical study2012
- Author(s)
  K. Kashima, H. Hiroiwa, Y. Yuki, H. Kiyono.
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Characterization of effector/memory CD4 T cells expanded in the mice vaccinated with MucoRice-CTB2012
- Author(s)
  EJ. Park, S. Joo, S. Kurokawa, H. Kiyono, Y. Yuki
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] コメ型経口ワクチンMucoRice-CTBの研究開発2012
- Author(s)
  幸義和
- Organizer
  日本薬学会
- Place of Presentation
  札幌(招待講演)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] ブタ大腸菌性下痢症予防食べるワクチンの開発研究2012
- Author(s)
  幸義和
- Organizer
  動物ワクチン-バイオ医薬研究会
- Place of Presentation
  盛岡(招待講演)
- Year and Date
  2012-09-04
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] MucoRice-CTB as an oral vaccine for the prevention of entroxigenic E. coli-mediated diarrhea in pigs.2012
- Author(s)
  Takeyama, K. Oroku, D. Tokuhara, S. Nagai, H. Kiyono, Y. Yuki
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Rice-based oral vaccine of cholera toxin B subunit for the protection of enteroxigenic Escherichia coli infection in pigs2011
- Author(s)
  N. Takayama, D. Tokuhara, T. Nochi, K. Oroku, S. Nagai, A. Chubachi, K. Tuchiya, Y. Yuki & H. Kiyono
- Organizer
  3rd World Congress of Vaccine
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] In vivo molecular imaging for a nasal botulism vaccine in mice and nonhuman primates2011
- Author(s)
  Y. Yuki, T. Nochi, N. Harada, Y. Katakai, H. Tsukada, & H. Kiyono
- Organizer
  Vaccine and ISV Annual Global Congress
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] L. Hammarstrom. Rice-based oral antibody prophylaxis and therapy against rotavirus infection2011
- Author(s)
  Y. Yuki, D. Tokuhara, B. A. Gonzalez, H. Marcotte, L. Frenken, M. Iturriza, H. Kiyono
- Organizer
  日本免疫学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] In vivo molecular imaging for a nasal botulism vaccine in mice and nonhuman primates2011
- Author(s)
  Y. Yuki, T. Nochi, N. Harada, Y. Katakai, M. Mejima, D. Tokuhara, S. Kurokawa, Y. Takahashi, H. Shibata, T. Kohda, S. Kozaki, H. Tsukada, & H. Kiyono
- Organizer
  The American Association of Immunologists (AAI)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Passive oral rice-based antibody prophylaxis and therapy against rotavirus infection2011
- Author(s)
  D. Tokuhara, B. Gonzalez, M. Mejima, Y. Takahashi, S. Kurokawa, T. Hiroiwa, M. Kuroda, M. Oyama, H. Kozuka-Hata, T. Nochi, F. Aladin, H. Marcotte, L. Frenken, M. Iturriza, H. Kiyono, L. Hammarstrom, & Y. Yuki
- Organizer
  The American Association of Immunologists (AAI)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] 経鼻ワクチンの安全性:マウスおよびサルに経鼻投与されたワクチンのリアルタイム分子イメージング2011
- Author(s)
  幸義和、清野宏
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] In vivo molecular imaging analysis of a nasal vaccine.2011
- Author(s)
  Y.Yuki, et.al.
- Organizer
  3rd World Congress of Vaccine
- Place of Presentation
  Beijing, China
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Indispensableness of vaccine -delivery to Peyer's patch and villous M cells for the induction of antigen-specific immune response2011
- Author(s)
  GS. Pontes, T. Nochi, H. Nakamura-Adachi, Y. Kurashima, J. Kunisawa, Y. Yuki & H. Kiyono
- Organizer
  International congressof Mucosal Immunology (ICMI)
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Nanogel based adjuvant-free Pneumococcal nasal vaccine induces protective immunity against Pneumococcus2011
- Author(s)
  IG. Kong, Y. Yuki, A. Sato-Kimura, T. Nochi, H. Takahashi, S. Sawada, M. Mejima, S. Kurokawa, D. Tokuhara, K. Okada, S. Sato, D. Briles, K. Akiyoshi & H. Kiyono
- Organizer
  International congressof Mucosal Immunology (ICMI)
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] アジュバント不要ナノゲル型経鼻ワクチンの開発2010
- Author(s)
  幸義和, ら
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京九段会館
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] An efficient rice-based expression system producing nasally immunogenic non-toxic subunit fragment of Clostridium Botulinum type-A neutrotoxin2010
- Author(s)
  Y. Yuki, M. Mejima, M. Kuroda, S. Kurokawa, T. Hiroiwa, IG kong, Y. Takahashi, YG, Chen, T. Nochi, D. Tokuhara, T. Kohda, S. Kozaki & H. Kiyono
- Organizer
  International congressof Mucosal Immunology (ICMI)
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Oral rice-based vaccine induced active and passive immunity against E. coli-mediated diarrhea in pigs2010
- Author(s)
  N. Takeyama, D. Tokuhara, K. Oroku, M. Mijima, S. Kurokawa, Y. Takahashi, M. Kuroda, T. Hiroiwa, YG, Chen, A. Chubachi, T. Nochi, T. Masumura, K. Tanaka, T. Kodama, S. Nagai, T. Nunoya, H. Kiyono & Y. Yuki
- Organizer
  International congressof Mucosal Immunology (ICMI)
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] A rice-based oral cholera vaccine induces macaque-specific systemic neutralizing Abs but does not influence natural intestinal immunity2010
- Author(s)
  Y.Yuki, et.al.
- Organizer
  The American Association of Immunologists
- Place of Presentation
  Baltimore, USA
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Exploit of Novel Delivery System with Nanogel for Development of Adjuvant-Free Nasal Vaccine2010
- Author(s)
  Y. Yuki, T. Nochi, H. Takahashi, S. Sawada, M. Mejima, T. Kohda, N. Harada, N. Kataoka, IG. Kong, A. Sato, D. Tokuhara, S. Kurokawa, Y. Takahashi, H. Tsukada, S. Kozaki, K. Akiyoshi, H. Kiyono
- Organizer
  International conference of Immunology
- Place of Presentation
  Kobe. Japan
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Exploit of Novel Delivery System with Nanogel for Development of Adjuvant-Free Nasal Vaccine.2010
- Author(s)
  Y.Yuki, et.al.
- Organizer
  International conference of Immunology
- Place of Presentation
  Kobe, Japan 神戸国際展示場
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Exploit of Nanogel-based Delivery System for Adjuvant-free Intranasal Vaccines2010
- Author(s)
  Y. Yuki
- Organizer
  8th Annual Vaccines: All Things Considered Conference
- Place of Presentation
  Washington, DC USA
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] A Novel Nanogel-based Delivery System for Adjuvant-free Intranasal Vaccines2010
- Author(s)
  Y. Yuki
- Organizer
  2nd World Congress of Vaccine
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Secretory IgA responses induced by rice-based oral cholera toxin B subunit vaccine are solely responsible for antibody-mediated long-standing cross-protection against Vibrio cholerae- and enterotoxigenic Escherichia coli- induced diarrhea2010
- Author(s)
  D. Tokuhara, Y. Yuki, T. Nochi, T. Kodama, M. Mejima, S. Kurokawa, Y. Takahashi, M. Nanno, F. Takaiwa, T. Honda, H. Kiyono
- Place of Presentation
  Baltimore, USA
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Nanogel antigen delivery system for adjuvant-free intranasal vaccines2010
- Author(s)
  T. Nochi, Y. Yuki, H. Takahashi, S. Sawada, M. Mejima, T. Kohda, N. Harada, N. Kataoka, IG. Kong, A. Sato, D. Tokuhara, S. Kurokawa, Y. Takahashi, H. Tsukada, S. Kozaki, K. Akiyoshi, H. Kiyono
- Place of Presentation
  Baltimore, USA
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] A rice-based oral cholera vaccine induces macaque-specific systemic neutralizing Abs but does not influence natural intestinal immunity2010
- Author(s)
  Y. Yuki, T. Nochi, Y. Katakai, H. Shibata, D. Tokuhara, M. Mejima, S. Kurokawa, Y. Takahashi, H. Hatai, A. Chubachi, U. Nakanishi, K. Terao, H. Kiyono
- Place of Presentation
  Baltimore, USA
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] アジュバント不要ナノゲル型経鼻ワクチンの開発2010
- Author(s)
  幸義和、野地智法、秋吉一成、清野宏
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] In vivo molecular imaging analysis of a nasal vaccine2010
- Author(s)
  Y. Yuki, T. Nochi, N. Harada, Y. Katakai, H. Shibata, M. Mejima, T. Kohda, D. Tokuhara, S. Kurokawa, Y. Takahashi, F. Ono, S. kazaki, K. Terao, H. Tsukada, H. Kiyono
- Organizer
  3rd World Congress of Vaccine
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] 米型コレラ毒素B鎖ワクチンは分泌型IgAを誘導することでコレラ菌による下痢を長期間防御する2010
- Author(s)
  幸義和、徳原大介、野地智法、児玉年央、目島未央、黒河志保、高橋裕子、南野昌信、本田武司、清野宏
- Organizer
  日本細菌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Exploit of Nanogel-based Delivery System for Adjuvant-free Intranasal Vaccines. 8th Annual Vaccines2010
- Author(s)
  Y.Yuki
- Organizer
  8th Annual Vaccines : All Things Considered Conference
- Place of Presentation
  Washington, DC USA(招待講演)
- Year and Date
  2010-11-09
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] コレラ毒素Bサブユニット発現コメ型経口ワクチンによるコレラ菌および毒素原性大腸菌に対する下痢予防効果の検証2009
- Author(s)
  徳原大介、幸義和、野地智法、清野宏
- Organizer
  日本ワクチン学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] コレラ毒素Bサブユニット(CTB)発現米はカニクイザルへの経口投与により血清中にCT特異的IgG抗体を誘導するが、自然抗体として腸管に存在するCT特異的SIgA抗体の免疫応答には影響を与えない2009
- Author(s)
  幸義和、野地智法、徳原大介、清野宏
- Organizer
  日本ワクチン学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Development of a cold-chain free Rice-based oral vaccine : MucoRice2009
- Author(s)
  幸義和
- Organizer
  International collabotarion in Biotechnology : Research and Industry
- Place of Presentation
  osaka
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21200073
[Presentation] Characterization of effector/memory CD4 T cells expanded in the mice vaccinated with MucoRice-CTB
- Author(s)
  EJ. Park, S. Joo, S. Kurokawa, H. Kiyono, Y. Yuki.
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] Critical role of TSLP-TSLPR interaction in inducing secretory IgA responses after mucosal immunization
- Author(s)
  J. Sunyi, Y. Fukuyama, Y. Yuki, et.al.
- Organizer
  日本免疫学会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] Molecularly Uniform Rice-based Oral Cholera Toxin B Subunit Vaccine without Plant-associated Sugar Modification induces toxin-specific neutralizing immunity in mice and macaques
- Author(s)
  Y. Yuki, M. Mejima, S. Kurokawa et.al.
- Organizer
  15th International congress of immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] アジュバントフリーナノゲル型肺炎球菌経鼻ワクチンのサルでの免疫効果と安全性
- Author(s)
  幸　義和、清野宏
- Organizer
  日本ワクチン学会
- Place of Presentation
  福岡
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] Heat tolerance evaluation of the rice type oral cholera vaccine, MucoRice-CTB, for a clinical study
- Author(s)
  K. Kashima, H. Hiroiwa, Y. Yuki, H. Kiyono.
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] Establishment of murine norvirus S7 infection system for vaccine development
- Author(s)
  N. Takayama, Y. Chen et.al.. & Y. Yuki
- Organizer
  15th International congress of immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] ブタ大腸菌性下痢症予防食べるワクチンの開発研究
- Author(s)
  幸　義和
- Organizer
  動物ワクチンーバイオ医薬研究会
- Place of Presentation
  盛岡
- Invited
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] Regional T memory and miRNA biomarkers revealed by oral vaccination with MucoRice-CTB
- Author(s)
  EJ Park, Y. Yuki, H, Kiyono
- Organizer
  日本免疫学会
- Place of Presentation
  幕張、千葉県
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] MucoRice-CTB as an oral vaccine for the prevention of entroxigenic E. coli-mediated diarrhea in pigs.
- Author(s)
  N. Takeyama, K. Oroku, D. Tokuhara, S. Nagai, H. Kiyono, Y. Yuki.
- Organizer
  日本ワクチン学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] Nanogel-based PspA nasal vaccine induces S. pneumoniae-specific neutralizing antibody immune responses in non-human primates.
- Author(s)
  Y. Fukuyama, Y. Yuki, Y. Katakai et.al
- Organizer
  15th International congress of immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] 幸　義和、清野　宏：経鼻投与された粘膜アジュバントであるコレラトキシンは嗅覚神経を破壊する
- Author(s)
  幸　義和、清野　宏
- Organizer
  日本ワクチン学会
- Place of Presentation
  津、三重県
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] Adjuvant-free nanogel-based PspA nasal vaccine for the induction of protective immunity against Pneumococcus
- Author(s)
  Y. Yuki, IG.　Kong, A. Sato,et.al.
- Organizer
  The American Association of Immunologists
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24659203
[Presentation] Establishment of selection marker-free rice-based oral cholera toxin B-subunit vaccine and characterization of location and structure of transgene by using whole genome resequencing analysis
- Author(s)
  Y.Yuki, M. Mejima, K.Kashima et.al.
- Organizer
  International Association for Plant Biotechnology Congress
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2014-08-11 – 2014-08-15
- Data Source
  KAKENHI-PROJECT-24659203

1. KIYONO Hiroshi (10271032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. KUNISAWA Jun (80376615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SATO Shintaro (80447333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. Nakahashi Rika (80391887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUKUYAMA Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. MEJIMA Mio

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. KUROKAWA Shiho

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. SUZUKI Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 川口寧

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 大内田理佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

YUKI Yoshikazu 幸 義和

Research Projects

Research Products

Co-Researchers

Basic research for the TB vaccine development based on the novel drug delivery system.

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New attempt of cold-chain free oral influenza vaccine developmentPrincipal Investigator

Principal Investigator

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Development of cold - chain free oral protein-based drugPrincipal Investigator

Principal Investigator

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Research Institution

Analysis of antigen-uptake network at mucosal epithelial layer

Principal Investigator

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[Book] 注射剤・経口製剤に代る新しい薬剤投与ヂバイスの開発―2014

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[Book] 粘膜ワクチン製剤のＤＤＳ技術の動向と実用化の可能性―2013

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[Book] ワクチンのDDS技術の開発動向―経鼻投与技術動向― 「ワクチンの市場動向と開発・製造実務集」2012

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[Book] ワクチンのDDS技術の開発動向-経鼻投与技術動向- 「ワクチンの市場動向と開発・製造実務集」2012

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[Book] ワクチンのDDS技術の開発動向-経口投与技術動向- 「ワクチンの市場動向と開発・製造実務集」2012

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[Book] ワクチンの市場動向と開発・製造実務集2012

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[Book] 臨床粘膜免疫学(経口ワクチン、p532-539)2010

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[Book] Allergy Frontiers : Future Perspectives(Transgenic Rice)2009

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[Journal Article] A role for the CCR5?CCL5 interaction in the preferential migration of HSV-2-specific effector cells to the vaginal mucosa upon nasal immunization2019

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[Journal Article] Nanogel-based nasal vaccines for infectious and lifestyle-related diseases.2019

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[Journal Article] ナノゲルデリバリーシステムによる肺炎球菌経鼻ワクチンの開発2019

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[Journal Article] 粘膜ワクチンの潮流と課題2018

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[Journal Article] Cationic pullulan nanogel as a safe and effective nasal vaccine delivery system for respiratory infectious diseases.2018

YUKI Yoshikazu 幸義和

[Book] ワクチンのDDS技術の開発動向―経鼻投与技術動向―　「ワクチンの市場動向と開発・製造実務集」2012