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OKAMOTO Hiroyuki  岡本 宏之

ORCIDConnect your ORCID iD *help
… Alternative Names

岡本 宏之  オカモト ヒロユキ

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Researcher Number 60348266
Affiliation (based on the past Project Information) *help 2016: 東京大学, 医学部附属病院, 登録研究医
2015: 東京大学, 医学部附属病院, 登録研究員
2014: 東京大学, 医学部附属病院, その他
2014: 東京大学, 医学部附属病院, 登録研究医
2013: 東京大学, 医学部附属病院, 特任教師 … More
2011 – 2013: 東京大学, 医学部附属病院, 特任講師
2009 – 2011: The University of Tokyo, 医学部附属病院, 助教
2008: 東京大学, 医学部・附属病院, 助教
2005: 東京大学, 医学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
General surgery
Except Principal Investigator
General surgery / Cardiovascular surgery
Keywords
Principal Investigator
構造解析 / 腹部大動脈瘤 / 瘤 / シミュレーション / ステントグラフト / 大動脈 / torsion / curvature / aortic aneurysm / migration … More / stent graft / modeling system / simulation / 抗血栓性 / MPCポリマー / 小口径人工血管 … More
Except Principal Investigator
血管外科学 / Surgery / 循環器・高血圧 / 外科 / 腹部大動脈瘤 / Tissue / Cell / Vascular / regenerative medicine / transplant / Signal pathway / 小口径人口血管 / 吻合部内膜肥厚 / 細胞・組織 / 移植・再生医療 / シグナル伝達 / Circulation, Hypertension / Nano-material / ナノ材料 / model / saccular / stent graft migration / 大動脈瘤モデル / 大動脈瘤 / 破裂 / 嚢状瘤 / stress / rupture / aortic aneurysm / simulation / ナノ粒子 / ドラッグデリバリーシステム / PICsome / Drug Delivery System / ドラッグデリバリー / ナノミセル / drug delivery system / 血管外科 / 人工血管 / 塩基性線維芽細胞増殖因子 / ラビット虚血肢モデル / 血管新生療法 / 側副血行路 / 再生医療 / RNA干渉 / 血管再生 / 低酸素誘導因子 / 乳癌抑制遺伝子 / 低酸素応答因子 / 血管新生 / 血管外外科一般 / コラーゲン線維束 / 腹部大動脈 / コラーゲン線維 / 加齢変化 / レボビスト / 無侵襲治療 / 下肢静脈瘤 / HIFU / ステント留置後再狭窄 / electroporation / 炎症性シグナル伝達 / TRAF / 内膜肥厚 / バルーン障害モデル Less
  • Research Projects

    (12 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (18 People)
  •  Medical and Technological approach for creating the guideline of risk prediction of aortic aneurysm rupture

    • Principal Investigator
      Hoshina Katsuyuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      The University of Tokyo
  •  Simulation of chronological changes of the stent graft after implantation in the abdominal aortic aneurysmPrincipal Investigator

    • Principal Investigator
      OKAMOTO Hiroyuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  A novel drug delivery system targeting the aortic wall

    • Principal Investigator
      HOSHINA Katsuyuki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Molecular pathological analyses of collateral augmentation for a development of novel angiogenic therapy

    • Principal Investigator
      MIYATA Tetsurou
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Experimental evaluation of a silk fibroin-coated vascular prosthesis

    • Principal Investigator
      SHIGEMATSU Kunihiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Development of small-diameter vascular graft composed of antithrombogenic phospholipid polymerPrincipal Investigator

    • Principal Investigator
      OKAMOTO Hiroyuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Silencing of Int6 Promotes Recovery of Blood Perfusion after Limb Ischemia via Stabilizing Hypoxia-Inducible Factor 2α

    • Principal Investigator
      KIMURA Hideo
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Development of a less invasive treatment for varicose veins with high intensity focused ultrasound

    • Principal Investigator
      MIYATA Tetsuro, NISHIKAGE Seiji
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Structural analysis of collagen fiber of arterial wall in patients with abdominal aortic aneurysm

    • Principal Investigator
      SHIGEMATSU Kunihiro, 出口 順夫
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  炎症性シグナルの制御による新しいステント内再狭窄発生予防の開発

    • Principal Investigator
      石井 誠之
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Gene delivery using polyion complex micelle for the treatment of aortic aneurysm

    • Principal Investigator
      MIYATA Tetsuro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Signal pathway in anastomotic intimal hyperplasia : to establish the strategy for anastomis intimal hyperplasia after bypass grafting with small diameter prosthesis

    • Principal Investigator
      SHIGEMATSU Kunihiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo

All 2014 2013 2012 2005 Other

All Journal Article Presentation

  • [Journal Article] The effect of recombinant human soluble thrombomodulin on disseminated intravascular coagulation in an abdominal aortic aneurysm2013

    • Author(s)
      Hoshina K, Shigematsu K, Okamoto H, Miyata T, et al.
    • Journal Title

      Blood Coagul Fibrinolysis

      Volume: 25 Pages: 389-391

    • Data Source
      KAKENHI-PROJECT-23591859
  • [Journal Article] – A Device-Specific Analysis –2013

    • Author(s)
      Hoshina K, Okamoto H, Shigematsu K, Miyata T, et al.
    • Journal Title

      Circ J

      Volume: 77 Issue: 8 Pages: 1996-2002

    • DOI

      10.1253/circj.CJ-13-0204

    • NAID

      10031178667

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591859, KAKENHI-PROJECT-24591866
  • [Journal Article] Aortic dissectin occurring 18 months after successful endovascular repair in an anatomical difficult case of abdominal aortic aneurysm.2013

    • Author(s)
      Yamamoto S, Hoshina K, Takazawa Y, Okamoto H, Shigematsu K, Miyata T, Watanabe T.
    • Journal Title

      Case Report Vasc Med

      Volume: 412708 Pages: 412708-412708

    • DOI

      10.1155/2013/412708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591866
  • [Journal Article] The effect of recombinant human soluble thrombomodulin on disseminated intravascular coagulation in an abdominal aortic aneurysm2013

    • Author(s)
      Hoshina K, Shigematsu K, Hosaka A, Okamoto H, Miyata T, Watanabe T.
    • Journal Title

      Blood Coagulation and Fibrinolysis

      Volume: Epub ahead of print Issue: 4 Pages: 1-1

    • DOI

      10.1097/mbc.0000000000000031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Journal Article] Study Design of PROCEDURE Study a Randomized Comparison of the Dose-Dependent Effects of Pitavastatin in Patients with Abdominal Aortic Aneurysm with Massive Aortic Atheroma: Prevention of Cholesterol Embolization during Endovascular and Open Aneurysm Repair with Pitavastatin(PROCEDURE) Study2013

    • Author(s)
      Hoshina K, Nemoto M, Hashimoto T, Miura S, Urabe G, Nakazawa T, Hosaka A, Kato M, Ohkubo N, Miyairi T, Okamoto H, Shigematsu K, Miyata T
    • Journal Title

      Ann Vasc Dis

      Volume: 6 Issue: 1 Pages: 62-66

    • DOI

      10.3400/avd.oa.12.00064

    • NAID

      130004487985

    • ISSN
      1881-641X, 1881-6428
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591859, KAKENHI-PROJECT-24591866
  • [Journal Article] Endovascular Surgery for Inflammatory Abdominal Aortic Aneurysm with Contrast Allergy—Usefulness of Carbon Dioxide Angiography and Intravascular Ultrasound: A Case Report2012

    • Author(s)
      Morito H, Hoshina K, Hosaka A, Okamoto H, Shigematsu K, Miyata T.
    • Journal Title

      Ann Vasc Dis

      Volume: 5 Issue: 1 Pages: 104-108

    • DOI

      10.3400/avd.cr.11.00087

    • NAID

      130004695426

    • ISSN
      1881-641X, 1881-6428
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Journal Article] Outcomes after open surgery and endovascular aneurysm repair for abdominal aortic aneurysm in patients with massive neck atheroma.2012

    • Author(s)
      Hoshina K, Hosaka A, Takayama T, Kato M, Ohkubo N, Okamoto H, Shigematsu K, Miyata T.
    • Journal Title

      Eur J Vasc Endovasc Surg

      Volume: 43 Issue: 3 Pages: 257-261

    • DOI

      10.1016/j.ejvs.2011.11.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Journal Article] Lessons learned from a case of abdominal aortic aneurysm accompanied by unstable coagulopathy.2012

    • Author(s)
      Hoshina K, Kaneko M, Hosaka A, Okamoto H, Shigematsu K, Miyata T.
    • Journal Title

      Case Report in Vascular Medicine

      Volume: 265860 Pages: 1-5

    • DOI

      10.1155/2012/265860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591859, KAKENHI-PROJECT-24591866
  • [Journal Article] Acute Remodeling of an Adjoining Aneurysm after Endovascular Treatment of a Ruptured Splanchnic Arterial Aneurysm: A Case of Clinically Diagnosed Segmental Arterial Mediolysis2012

    • Author(s)
      Nishikawa Y, Hoshina K, Sasaki H, Hosaka A, Yamamoto K, Okamoto H, Shigematsu K, Miyata T.
    • Journal Title

      Ann Vasc Dis

      Volume: 5 Issue: 4 Pages: 449-453

    • DOI

      10.3400/avd.cr.12.00060

    • NAID

      130004713555

    • ISSN
      1881-641X, 1881-6428
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591859, KAKENHI-PROJECT-24591866
  • [Journal Article] Clinical implication of plasma level of soluble fibrin monomer-fibrinogen complex in patients with abdominal aortic aneurysm.2005

    • Author(s)
      Hosaka A, Miyata T, Aramoto H, Shigematsu H, Nakazawa T, Okamoto H, Shigematsu K, Nagawa H.
    • Journal Title

      Journal of Vascular Surgery 42(2)

      Pages: 200-205

    • Data Source
      KAKENHI-PROJECT-17591322
  • [Journal Article] Long-term outcome after surgical treatment of arterial lesions in Behcet disease.2005

    • Author(s)
      Hosaka A, Miyata T, Shigematsu H, Shigematsu K, Okamoto H, Ishii S, Miyahara T, Yamamoto K, Akagi D, Nagayoshi M, Nagawa H.
    • Journal Title

      Journal of Vascular Surgery 42(1)

      Pages: 116-121

    • Data Source
      KAKENHI-PROJECT-17591322
  • [Journal Article] Persistent sciatic artery in a patient with extracranial internal carotid artery aneurysm and infrarenal abdominal aortic aneurysm : A case report.2005

    • Author(s)
      Miyahara T, Miyata T, Shigematsu K, Shigematsu H, Koyama H, Okamoto H, Nakazawa T, Nagawa H.
    • Journal Title

      International Angiology 24(4)

      Pages: 391-394

    • Data Source
      KAKENHI-PROJECT-17591322
  • [Journal Article] Long-term results of combined iliac endovascular intervention and infrainguinal surgical revascularization for treatment of multilevel arterial occlusive disease.2005

    • Author(s)
      Miyahara T, Miyata T, Shigematsu H, Shigematsu K, Okamoto H, Nakazawa T, Nagawa H.
    • Journal Title

      International Angiology 24(4)

      Pages: 340-348

    • NAID

      10016793457

    • Data Source
      KAKENHI-PROJECT-17591322
  • [Presentation] ステントグラフト留置後の形態変化の評価:モデリングシステムの開発2014

    • Author(s)
      保科克行、小林匡治、大島まり、山本創太、赤井隆文、根元洋光、保坂晃弘、宮原拓也、岡本宏之、重松邦広、宮田哲郎、渡邉聡明
    • Organizer
      第44回日本心臓血管外科学会総会
    • Place of Presentation
      熊本(ホテル日航熊本)
    • Data Source
      KAKENHI-PROJECT-24591866
  • [Presentation] 大動脈瘤の二次元構造解析による嚢状瘤の定義2014

    • Author(s)
      保科克行、赤井隆文、竹内浩明、山本創太、大島まり、根元洋光、西山綾子、宮原拓也、保坂晃弘、岡本宏之、重松邦広、宮田哲郎、渡邉聡明
    • Organizer
      日本外科学会定期学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-04-04
    • Data Source
      KAKENHI-PROJECT-26462101
  • [Presentation] 大動脈瘤の二次元構造解析による嚢状瘤の定義2014

    • Author(s)
      保科克行 、赤井隆文、竹内浩明、山本創太、大島まり、根元洋光、西山綾子、宮原拓也、保坂晃弘、岡本宏之、重松邦広、宮田哲郎、渡邊聡明
    • Organizer
      第114回日本外科学会定期学術集会
    • Place of Presentation
      京都(国立京都国際会館)
    • Data Source
      KAKENHI-PROJECT-24591866
  • [Presentation] 腹部ステントグラフト術後3年以上の検討:デバイスと瘤のinteractionにみる有害事象の兆し2013

    • Author(s)
      保科克行、橋本拓弥、加藤雅明、白須拓郎、芳賀真、望月康晃、赤井隆文、谷口良輔、根本卓、松倉満、山本諭、赤井淳、西山綾子、保坂晃弘、宮原拓也、岡本宏之、重松邦広、宮田哲郎
    • Organizer
      第41回日本血管外科学会学術総会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Presentation] 大動脈ステントグラフトのbranch protection:最善の手法とは?2013

    • Author(s)
      保科克行、加藤雅明、根本卓、須原正光、白須拓郎、芳賀真、望月康晃、根元洋光、松倉満、赤井隆文、谷口良輔、山本諭、西山綾子、保坂晃弘、宮原拓也、岡本宏之、重松邦広、宮田哲郎、渡邉聡明
    • Organizer
      第54回日本脈管学会総会
    • Place of Presentation
      東京(ステーションコンファレンス東京)
    • Data Source
      KAKENHI-PROJECT-24591866
  • [Presentation] Type 2 Endoleakに対するコイル塞栓術3例と今後の治療戦略について2013

    • Author(s)
      保科克行、赤羽正章、保坂晃弘、加藤雅明、宮原拓也、岡本宏之、重松邦広、大久保修和、宮田哲郎
    • Organizer
      第17回大動脈ステントグラフト研究会
    • Place of Presentation
      青森(ホテル青森)
    • Data Source
      KAKENHI-PROJECT-24591866
  • [Presentation] Type 2 Endoleakに対するコイル塞栓術3例と今後の治療戦略について2013

    • Author(s)
      保科克行、赤羽正章、保坂晃弘、加藤雅明、宮原拓也、岡本宏之、重松邦広、大久保修和、宮田哲郎
    • Organizer
      第17回大動脈ステントグラフト研究会
    • Place of Presentation
      青森(ホテル青森第二会場)
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Presentation] 腹部ステントグラフト術後3年以上の検討:デバイスと瘤のinteractionにみる有害事象の兆し2013

    • Author(s)
      保科克行、岡本宏之、重松邦広、宮田哲郎, ほか
    • Organizer
      第41回日本血管外科学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2013-05-30
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Presentation] 大動脈ステントグラフトのbranch protection:最善の手法とは?2013

    • Author(s)
      保科克行、加藤雅明、根本卓、須原正光、白須拓郎、芳賀真、望月康晃、根元洋光、松倉満、赤井隆文、谷口良輔、山本諭、西山綾子、保坂晃弘、宮原拓也、岡本宏之、重松邦広、宮田哲郎、渡邉聡明
    • Organizer
      第54回日本脈管学会総会
    • Place of Presentation
      東京(ステーションコンファレンス東京)
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Presentation] 大動脈ステントグラフトのbranch protection:最善の手法とは?2013

    • Author(s)
      保科克行、岡本宏之、重松邦広、宮田哲郎, ほか
    • Organizer
      第54回日本脈管学会総会
    • Place of Presentation
      東京
    • Year and Date
      2013-10-10
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Presentation] Type 2 Endoleakに対するコイル塞栓術3例と今後の治療戦略について2013

    • Author(s)
      保科克行、岡本宏之、重松邦広、宮田哲郎, ほか
    • Organizer
      第17回大動脈ステントグラフト研究会
    • Place of Presentation
      青森
    • Year and Date
      2013-07-20
    • Data Source
      KAKENHI-PROJECT-23591859
  • [Presentation] 絹タンパク(フィブロイン)の人工血管材料としての使用経験2012

    • Author(s)
      岡本宏之
    • Organizer
      第53回日本脈管学会総会
    • Place of Presentation
      東京
    • Year and Date
      2012-10-11
    • Data Source
      KAKENHI-PROJECT-22591398
  • [Presentation] 瘤頸部高度屈曲症例に対するステントグラフト内挿術後の経時的変化と合併症:デバイスごとの検討とシミュレーションの役割2012

    • Author(s)
      保科克行、赤井隆文、加藤雅明、浦部豪、中澤達、大島まり、山本創太、白須拓郎、芳賀真、望月康晃、松倉満、谷口良輔、根本卓、山本諭、赤井淳、西山綾子、保坂晃弘、岡本宏之、重松邦広、宮田哲郎
    • Organizer
      第53回日本脈管学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24591866
  • [Presentation] 絹タンパク(フィブロイン)の人工血管材料としての使用経験

    • Author(s)
      岡本宏之
    • Organizer
      第53回日本脈管学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22591398
  • 1.  MIYATA Tetsuro (70190791)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 21 results
  • 2.  SHIGEMATSU Kunihiro (20215966)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 21 results
  • 3.  KOYAMA Hiroyuki (10241994)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 1 results
  • 4.  KIMURA Hideo (60327070)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 5.  HOSHINA Katsuyuki (90571761)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 6.  OHSHIMA Mari (40242127)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 7.  NISHIKAGE Seiji (30431844)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  石井 誠之 (80365197)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  重松 宏 (40134556)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 10.  出口 順夫 (50242053)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  MATSUMOTO Yoichiro (60111473)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  FUKAYAMA Masahisa (70281293)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ASAKURA Tetsuo (30139208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YAMAMOTO Sota (80293653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  YAMAMOTO Kota (00753542)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  OBA Makoto (20396716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  DEGUCHI Jyun-o (80323591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  片岡 一則 (00130245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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