Mori Kazunori 森一憲

… Alternative Names

MORI Kazunori 森一憲

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Researcher Number	60349040
Other IDs
Affiliation (Current)	2025: 昭和医科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 昭和大学, 薬学部, 准教授 2016 – 2023: 昭和大学, 薬学部, 講師 2007 – 2016: 昭和大学, 薬学部, 助教 2009: Showa University, 薬学部・腫瘍細胞生物学, 助教 2002 – 2006: 昭和大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Cell biology / Basic Section 48030:Pharmacology-related / Basic Section 49010:Pathological biochemistry-related / Biological pharmacy / Biological pharmacy / Pathological medical chemistry / Biological Sciences
Keywords	Principal Investigator 活性酸素種 / ミトコンドリア / 足場依存性 / 足場非依存性増殖 / Hic-5 / 非依存性増殖 / 足場依存性増殖 / Integrin β4 / 転移抑制 / 細胞接着 … More / Rac1 / integrin beta4 / p21cip1 / 電子伝達系 / ミトコンドリア電子伝達系 / エネルギー代謝 / NAD+ / サイクリン依存性キナーゼ阻害因子p21Cip1 / ミトコンドリア呼吸鎖 / 活性酸素 / NOX4 / MMP-9 / NADPH oxidase 4 / MMP9 / 足場非依存性増殖能 / HIC-5 / がん転移抑制 / p21cipl / p21Cip1 / cyclin D1 / サイクリンD1 … More Except Principal Investigator ミトコンドリア / TGFβ / Hic-5 / c-fos / 活性酸素 / HMGA2 / MMP9 / 代謝ストレス応答 / 臓器横断的癌治療薬 / ミトコンドリアストレス応答機構 / 呼吸鎖 / AMPK / ミトコンドリアストレス応答 / 活性酸素種 / 転移 / レドックス / がん転移 / 足場非依存性増殖 / mitochondria / NADPH oxidase / reactive oxygen species / TGFb / 間葉系遺伝子 / EMT / プロテオーム / DNAアレイ / Nox4 / TGF-β / NADPHオキシダーゼ / focal adhesion / nuclear lozalization / paxillin / 上皮細胞 / p38 / MMP / 接着斑 / パキシリン / 細胞接着斑 / 核移行 / 核マトリクス / LIM蛋白質 / 酸化ストレス / レドクス / E2F1 / ミトコンドリア呼吸鎖活性 / 肝細胞がん / ミトコンドリアDNA変異 / ミトコンドリアDNA / プロテインキチーゼC / チオレドキシン / 膜電位 / CHOP-10 / CREB / matrix metalloproteinase / 遺伝子発現 / マトリックスメタロプロテアーゼ / サイクリンD1 / 足場依存性増殖 / cyclin D1 Less

転移抑制を目指したRac1によるintegrin β4の分解抑制機構の解明Principal Investigator
- Principal Investigator
  
  森一憲
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Showa University
Respiratory chain activity as a target of tumor-agnostic therapy in highly glycolytic/low respiratory tumors
- Principal Investigator
  
  柴沼質子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Showa University
Impact of mitochondrial complex I activity on cancer cell proliferation: importance of NAD+ levelsPrincipal Investigator
- Principal Investigator
  
  Kazunori Mori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Showa University
SUZ12 supresses anoikis by alleviating oxidative stress in cancer cells
- Principal Investigator
  
  Ishikawa Fumihiro
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Showa University
A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS-activated cancer cellsPrincipal Investigator
- Principal Investigator
  
  Mori Kazunori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa University
Significance of mitochondrial DNA mutations in cancer cells: induction of HMGA2 in response to DNA damage
- Principal Investigator
  
  Shibanuma Motoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa University
Suppressive role of the adaptor protein Hic-5 in anchorage-independent cell growthPrincipal Investigator
- Principal Investigator
  
  KAZUNORI Mori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa University
A molecular scaffold HIC-5-and KLF4-dependent mechanism transactivates p21^<Cip1> in response to loss of anchoragePrincipal Investigator
- Principal Investigator
  
  MORI Kazunori
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa University
A potential role of mitochondria-mediated signaling in induction of malignancy and stemness by TGF.
- Principal Investigator
  
  SHIBANUMA Motoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Showa University
Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage-dependence of cell growth and survivalPrincipal Investigator
- Principal Investigator
  
  KAZUNORI Mori
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa University
A novel cascade of TGF-β signaling dependent on mitochondrial reactive oxygen species and its biological significance
- Principal Investigator
  
  SHIBANUMA Motoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Showa University
細胞接着斑-核シャトル複合体による足場依存性増殖のための安全装置の破綻と癌化
- Principal Investigator
  
  SHIBANUMA Motoko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Showa University
Regulation of epithelial-mesenchymal transition (EMT) by redox-based mechanisms
- Principal Investigator
  
  NOSE Kiyoshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Showa University
Redox regulation of cell adhesion signals
- Principal Investigator
  
  NOSE Kiyoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Showa University

[Journal Article] An indispensable role of TAZ in anoikis resistance promoted by OTUB1 deubiquitinating enzyme in basal-like triple-negative breast cancer cells2023
- Author(s)
  Hidetsugu Nakagawa, Masato Higurashi, Fumihiro Ishikawa, Kazunori Mori, Motoko Shibanuma
- Journal Title
  
  Biochem Biophys Res Commun .
  
  Volume: 649 Pages: 1-9
- DOI
  10.1016/j.bbrc.2023.01.080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06917, KAKENHI-PROJECT-22K15516, KAKENHI-PROJECT-21K06809
[Journal Article] HMGA2 drives the IGFBP1/AKT pathway to counteract the increase in P27KIP1 protein levels in mtDNA/RNA-less cancer cells2022
- Author(s)
  Maruyama Tsuyoshi、Saito Koji、Higurashi Masato、Ishikawa Fumihiro、Kohno Yohko、Mori Kazunori、Shibanuma Motoko
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 1 Pages: 152
- DOI
  10.1111/cas.15582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06809, KAKENHI-PROJECT-22K06917, KAKENHI-PROJECT-22K15516
[Journal Article] Rac1-mediated sustained β4 integrin level develops reattachment ability of breast cancer cells after anchorage loss.2021
- Author(s)
  Mori K, Higurashi M, Ishikawa F, Shibanuma M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 112 Issue: 8 Pages: 3205-3217
- DOI
  10.1111/cas.14985
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07390
[Journal Article] Intracellular redox and mitochondrial regulaiton by transforming growth factor-b-its implication in induction of epithelial-mesenchymal transition2016
- Author(s)
  Motoko Shibanuma, Kazunori Mori, Fumihiro Ishikawa
- Journal Title
  
  J. Cell Signal.
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460399
[Journal Article] Linkage of E2F1 transcriptional network and cell proliferation with respiratory chain activity in breast cancer cells2016
- Author(s)
  Kazunori Mori et al.
- Journal Title
  
  Cancer Sci.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460399
[Journal Article] A HIC-5- and KLF4-dependent mechanism transactivates p21(Cip1) in response to anchorage loss.2012
- Author(s)
  Mori K, Hamanaka H, Oshima Y, Araki Y, Ishikawa F, Nose K, Shibanuma M.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 287 Issue: 46 Pages: 38854-38865
- DOI
  10.1074/jbc.m112.377721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590390
[Journal Article] A mobile molecular scaffold regulating the anchorage dependence of cell growth2011
- Author(s)
  Shibanuma, M., et.al.
- Journal Title
  
  Int J.Cell Biol.
  
  Volume: (in press) Pages: 1-8
- DOI
  10.1155/2012/426138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570205, KAKENHI-PROJECT-22790327
[Journal Article] A mobile molecular scaffold regulating the anchorage dependence of cell growth2011
- Author(s)
  柴沼質子、森一憲、野瀬清
- Journal Title
  
  Int J. Cell Biol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790327
[Journal Article] Importance of mitochondrial dysfunction in oxidative stress responses : A comparative study of gene expression profiles2011
- Author(s)
  Shibanuma, M., Inoue, A., Ushida, K., Uchida, T., Ishikawa, F., Mori, K., and Nose, K.
- Journal Title
  
  Free Radic. Res
  
  Volume: 45 Pages: 672-680
- Data Source
  KAKENHI-PROJECT-21570205
[Journal Article] Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage dependence of cell growth and survival.2009
- Author(s)
  Kazunori Mori, Eisuko Hirao, Yosuke Toya, Yukiko Oshima, Fumihiro Ishikawa, Kiyoshi Nose, Motoko Shibanuma
- Journal Title
  
  Molecular Biology of the Cell 20
  
  Pages: 218-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790263
[Journal Article] Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage-dependence of cell growth and survival2009
- Author(s)
  Mori, K., Hirao, E., Toya, Y., Oshima, Y., Ishikawa, F., Nose, K., and Shibanuma, M.
- Journal Title
  
  Mol. Biol Cell
  
  Volume: 20 Pages: 218-232
- Data Source
  KAKENHI-PROJECT-21570205
[Journal Article] Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage-dependence of cell growth and survival.2009
- Author(s)
  Mori, K., et al.
- Journal Title
  
  Mol. Biol Cell. 20
  
  Pages: 218-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570185
[Journal Article] Gene expression profiling identifies a role for CHOP-10 during inhibition of the mitochondrial respiratory chain2009
- Author(s)
  Ishikawa, F., Akimoto, T., Yamamoto, H., Araki, Y., Yoshie, T., Mori, K., Hayashi, H., Nose, K., and Shibanuma, M.
- Journal Title
  
  J. Biochem
  
  Volume: 146 Pages: 123-132
- Data Source
  KAKENHI-PROJECT-21570205
[Journal Article] Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage-dependence of cell growth and survival2009
- Author(s)
  Kazunori Mori, Etsuko Hirao, Yosuke Toya, Yukiko Oshima, Fumihiro Ishikawa, Kiyoshi Nose, Motoko Shibanuma
- Journal Title
  
  Mol. Biol Cell. 20
  
  Pages: 218-232
- Data Source
  KAKENHI-PROJECT-19570185
[Journal Article] Competitive nuclear export of cyclin DI and Hic-5 regulates anchorage dependence of cell growth and survival2009
- Author(s)
  kazunori Mori, Etsuko Hirao Yosuke Toya, Yukiko Oshima, Fumihiro Ishikawa Kivoshi Nose and Motoko
- Journal Title
  
  Molecular Biology of the Cell 20
  
  Pages: 218-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790263
[Journal Article] Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage dependence of cell growth and survival2009
- Author(s)
  Kazunori Mori, Etsuko Hirao, Yosuke Toya, Yukiko Oshima, Fumihiro Ishikawa, Kiyoshi Nose, Motoko Shibanuma
- Journal Title
  
  Molecular Biology of the Cell 20
  
  Pages: 218-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790263
[Journal Article] Anchorage-independent nuclear localization of cyclin D1 in v-ki-ras-expressing NIH3T3 cells2008
- Author(s)
  Kazunori Mori, Yosuke Toya, Kiyoshi Nose, Motoko Shibanuma
- Journal Title
  
  Tissue Culture Research communication 27
  
  Pages: 125-137
- NAID
  10025759271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790263
[Journal Article] Competitive nuclear export of cyclin Dl and Hic-5 regulates anchorage-dependence of cell growth and survival.2008
- Author(s)
  Mori, K., et. al.
- Journal Title
  
  J. Cell Biol. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013047
[Journal Article] 活性化rasによるcyclin D1核局在の接着依存性の喪失2008
- Author(s)
  森一憲、外谷陽介、野瀬清、柴沼質子
- Journal Title
  
  Tissue culture research communications 27
  
  Pages: 125-137
- NAID
  10025759271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790263
[Journal Article] Competitive nuclear export of cyclin Dl and Hic-5 regulates anchorage-dependence of cell growth and survival2008
- Author(s)
  Mori, K., et. al.
- Journal Title
  
  J. Cell Biol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570185
[Journal Article] Downregulation of hepatocyte nuclear factor-4α and its role in regulation of gene expression by TGF-β in mammary epithelial cells2008
- Author(s)
  Fumihiro, Ishikawa, Takashi Akimoto, Haruka Yamamoto, Yuri Araki, Toshihiko Yoshie, Kazunori Mori, Hidetoshi Hayashi, Kiyoshi Nose, Motoko Shibanuma
- Journal Title
  
  Exp. Cell Res. 314
  
  Pages: 2131-2141
- Data Source
  KAKENHI-PROJECT-19570185
[Journal Article] Characterization of Jumping translocation breakpoint (JTB) gene product isolated as a TGF-β1-inducible clone involved in regulation of mitochondrial function, cell growth and death.2007
- Author(s)
  Kanome, T., Itoh, N., Mori, K., Kim-Kaneyama, J., Shibanuma, M., Nose, K.
- Journal Title
  
  Oncogene. (in press)
- Data Source
  KAKENHI-PROJECT-18013047
[Journal Article] Characterization of Jumping translocation breakpoint (JTB) gene product isolated as a TGF-β1-inducible clone involved in regulation of mitochondrial function, cell growth and death.2007
- Author(s)
  Kanome, T., Itoh, N., Mori, K., Kim-Kaneyama, J., Shibanuma, M., Nose, K.
- Journal Title
  
  Oncogene (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Characterization of Jumping translocation breakpoint (JTB) gene product isolated as a TGF-β1-inducible clone involved in regulation of mitochondrial function, cell growth and death.2007
- Author(s)
  Kanome, T., Itho, N., Mori, K., Kim-Kaneyama, J., Shibanuma, M., Nose, K.
- Journal Title
  
  Oncogene. in press
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Oligomerizing potential of a focal adhesion LIM protein Hic-5 organizing a nuclear-cytoplasmic shuttling complex.2006
- Author(s)
  Mori, K., Asakawa, M., Hayashi, M., Imura, M., Ohki, T., Hirao, E., Nose, K., Shibanuma, M.
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 22048-22061
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Oligomerizing potential of a focal adhesion LIM protein Hic-5 organizing a nuclear-cytoplasmic shuttling complex.2006
- Author(s)
  Mori, K., Asakawa, M., Hayashi, M., Imura, M., Ohki, T., Hirao, E., Nose, K., Shibanuma, M.
- Journal Title
  
  J. Biol. Chem. 281巻・31号
  
  Pages: 22048-22061
- Data Source
  KAKENHI-PROJECT-18013047
[Journal Article] Oligomerizing potential of a focal adhesion LIM protein Hic-5 organizing a nuclear-cytoplasmic shuttling complex.2006
- Author(s)
  Mori, K., Asakawa, M., Hayashi, M., Imura, M., Ohki, T., Hirao, E., Nose, K., Shibanuma, M.
- Journal Title
  
  J. Biol. Chem. 281巻・31号
  
  Pages: 22048-22061
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Involvement of FAK and PTP-PEST in the regulation of redox-sensitive nuclear-cytoplasmic shuttling of a LIM protein, Hic-52005
- Author(s)
  M.Shibanuma, K.Mori, J.Kim-Kaneyama, K.Nose.
- Journal Title
  
  Antioxidants ＆ Redox Signaling 7巻・2号
  
  Pages: 335-347
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Involvement of FAX and PTP-PEST in the regulation of redox-sensitive nuclear-cytoplasmic shuttling of a LIM protein, Hic-52005
- Author(s)
  M.Shibanuma, K.Mori, Joo-ri Kim-Kaneyama, K.Nose
- Journal Title
  
  Antioxidants & Redox Signaling (In press)
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Involvement of FAK and PTP-PEST in the regulation of redox-sensitive nuclear-cytoplasmic shuttling of a LIM protein, Hic-5.2005
- Author(s)
  M.Shibanuma, K.Mori, J.Kim-Kaneyama, K.Nose.
- Journal Title
  
  Antioxidants ＆ Redox Signaling 7
  
  Pages: 335-347
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Involvement of FAK and PTP-PEST in the regulation of redox-sensitive nuclear-cytoplasmic shuttling of a LIM protein, Hic-52005
- Author(s)
  M.Shibanuma, K.Mori, Joo-riKim-Kaneyama, K.Nose
- Journal Title
  
  Antioxidants & Redox Signaling 7(3&4)
  
  Pages: 335-347
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Invasive potential induced under long-term oxidative stress in mammary epithelial cells.2004
- Author(s)
  Kazunori Mori, Motoko Shibanuma. Kivoshi Nose
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7464-7472
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] Characterization of Jumping translocation breakpoint (JTB) gene produc1 isolated as a TGF-pl-inducible clone involved in regulation of mitochondrial function, cell growth and death.
- Author(s)
  Kanome, T., Itoh, N., Mori, K., Kim-Kaneyama, J., Shibanuma, M., Nose, K.
- Journal Title
  
  Uncogene (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390025
[Journal Article] HIC-5 : A mobile molecular scaffold regulating the anchorage dependence of cell growth
- Author(s)
  Shibanuma, M., Mori, K., and Nose, K.
- Journal Title
  
  Int J. Cell Biol
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] NAD+-SIRT3/6によるp21Cip1発現制御と癌細胞増殖制御2023
- Author(s)
  日暮大渡、森一憲、中川　英嗣、石川文博、柴沼質子
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06809
[Presentation] Polycomb-group protein SUZ12 suppresses anoikis by alleviating oxidative stress in cancer cells2023
- Author(s)
  Ishikawa F, Mori K, Shibanuma M
- Organizer
  日本薬学会第143年会（札幌）
- Data Source
  KAKENHI-PROJECT-18K06969
[Presentation] HMGA2/IGFBP1/AKT経路によるP27KIP1分解機構の制御と癌治療標的としての意義2022
- Author(s)
  丸山剛、齊藤光次、日暮大渡、石川文博、河野葉子、森一憲、柴沼質子
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06809
[Presentation] Role of TAZ in promoting cell survival upon anchorage loss in breast cancer cells2022
- Author(s)
  Hidetsugu Nakagawa, Fumihiro Ishikawa, Kazunori Mori, Motoko Shibanuma
- Organizer
  The 81 st annual meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-22K06917
[Presentation] Epigenetic control of p21Cip1 expression and cell proliferation by respiratory chain complex I via NAD+ supply2021
- Author(s)
  Masato Higurashi, Kazunori Mori, Fumihiro Ishikawa, Motoko Shibanuma
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07390
[Presentation] ポリコーム群タンパク質SUZ12は酸化ストレスを緩和することでアノイキスを抑制する2021
- Author(s)
  石川文博、森一憲、柴沼質子
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06969
[Presentation] Rac1-mediated and sustained β4 integrin expression supports persistence of reattachment ability in breast cancer cells2021
- Author(s)
  Kazunori Mori, Masato Higurashi, Fumihiro Ishikawa, Motoko Shibanuma
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07390
[Presentation] HMGA2 is critical for sustaining cell proliferation in mtDNA-less hepatocellular carcinoma cells2021
- Author(s)
  Tsuyoshi Maruyama, Masato Higurashi, Kazunori Mori, Motoko Shibanuma
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07390
[Presentation] The impact of mitochondrial complex I activity on p21Cip1 expression: the importance of NAD+ levels2020
- Author(s)
  Kazunori Mori, Masato Higurashi, Fumihiro Ishikawa, Motoko Shibanuma
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07390
[Presentation] Impact of mitochondrial complex I activity on cancer cell proliferation: importance of NAD+ levels2019
- Author(s)
  Mori, K., Higurashi, M., Ishikawa, F., and Shibanuma, M.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07390
[Presentation] ミトコンドリア呼吸鎖複合体IはNAD+の供給を介してp21Cip1の発現を制御する2019
- Author(s)
  日暮大渡、森一憲、石川文博、柴沼質子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07390
[Presentation] Polycomb group protein SUZ12 suppresses anoikis by alleviating oxidative stress in cancer cells2019
- Author(s)
  Fumihiro Ishikawa, Kazunori Mori and Motoko Shibanuma
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06969
[Presentation] The HIC-5-NOX4-mtROS axis regulates metastasis of RAS-activated cancer cells by affecting MMP9 mRNA stability2017
- Author(s)
  Kazunori Mori, Tetsu Uchida, Toshihiko Yoshie, Yuko Mizote, Fumihiro Ishikawa, Masato Katsuyama, and Motoko Shibanuma
- Organizer
  EMBO Conference on Redox Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08317
[Presentation] HIC-5によるNOX4依存性細胞内レドックス制御とMMP-9発現制御2016
- Author(s)
  森一憲、石川文博、柴沼質子
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26460399
[Presentation] ポリコームタンパク質SUZ12は乳がん細胞の足場非依存的な生存を促進する2016
- Author(s)
  石川文博、森一憲、柴沼質子
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-26460399
[Presentation] HIC-5 acts as a negative regulator for MMP-9 expression by inhibiting NOX4 expression in oncogenic RAS-driven cancers2016
- Author(s)
  Kazunori Mori, Fumihiro Ishikawa, and Motoko Shibanuma
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K08317
[Presentation] 肝細胞がんに対する新規治療戦略：ATM/ATR-HMGA2経路の遮断による老化形質誘導の可能性2016
- Author(s)
  日暮大渡、斉藤光次、河野葉子、石川文博、森一憲、青木武士、村上雅彦、瀧本雅文、柴沼質子
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26460399
[Presentation] Phenotypic disruption of mammary epithelial cells caused by mitochondrial dysfunction and the underlying Mechanisms2012
- Author(s)
  Shibanuma, M., Mori, K., Ishikawa, F.
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Albert, Canada
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] Phenotypic disruption of mammary epithelial cells caused by mitochondrial dysfunction and the underlying mechanisms2012
- Author(s)
  Shibanuma, M., Mori, K., Ishikawa, F.
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Albert, Canada
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] Adhesion-sensitive transcriptional regulation of p21Cip is dependent on the molecular scaffold HIC-5 and KLF42012
- Author(s)
  Kazunori Mori, Fumihiro Ishikawa, Motoko Shibanuma
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24590390
[Presentation] A suppressive role of a focal adhesion protein, Hic-5, in anchorage-independent cell growth and tumorigenecity2011
- Author(s)
  森一憲、石川文博、柴沼質子
- Organizer
  70th annual meeting of the Japan cancer association
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22790327
[Presentation] 細胞接着斑蛋白質Hic-5によるがん細胞の足場非依存性増殖/造腫瘍能の抑制性制御2011
- Author(s)
  森一憲、石川文博、柴沼質子
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] Phenotypic disruption of mammary epithelial cells caused by mitochondrial dysfunction and the underlying mechanisms2011
- Author(s)
  Shibanuma, M., Mori, K., Ishikawa, F.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] ミトコンドリア機能不全によるEMTプログラムの活性化と上皮形質の破綻2011
- Author(s)
  柴沼質子、森一憲、石川文博
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] ミトコンドリア機能不全により誘導される上皮細胞形質の変化2010
- Author(s)
  石川文博、森一憲、柴沼質子
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] ミトコンドリア特異的転写因子TFAM発現抑制による腫瘍の転移能抑制の可能性2010
- Author(s)
  内田徹、石川文博、森一憲、柴沼質子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] Cell growth/death control by ROS, p21Cip1, and a focal adhesion protein, Hic-5, upon loss of intrinsic anchorage to ECM2010
- Author(s)
  森一憲、石川文博、柴沼質子
- Organizer
  69th Annual meeting of the Japanese cancer association
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790327
[Presentation] Mitochondria-mediated signaling cascade plays a role in the regulation of gene expression by TGF2010
- Author(s)
  Shibanuma, M., Kaneko, E., Sugimoto, T., Wakamatsu, M., Mori, K., Ishikawa, F.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] 細胞接着異常シグナルとしての活性酸素種、及びp21Cip1、細胞接着斑蛋白質Hic-5による足場依存性細胞増殖/生存制御2010
- Author(s)
  森一憲, 他
- Organizer
  第69回日本癌学会学術大会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21570205
[Presentation] 接着環境異常シグナルとしての活性酸素種、及びp21^<Cip1>による足場依存性細胞増殖/生存の制御2010
- Author(s)
  柴沼質子, 溝手優子, 大島由起子, 濱中浩之, 牛田喬太, 内田徹, 石川文博, 森一憲, 野瀬清
- Organizer
  日本組織培養学会第83回大会
- Place of Presentation
  岡山大学創立五十周年記念館ホール
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22790327
[Presentation] Involvement of focal adhesion-nucleus shuttling protein, Hic-5 imregulation of cell growth/survival of cancer cells2009
- Author(s)
  Toshihiko Yoshic, Kazunori Mori, Teisu Uchida, Hiroyuki Miyoshi, Fumihiro Ishikawa, Motoko Shibanuma
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20790263
[Presentation] Transactivation of the p21^<cipl> promoter by Hic-5, a focal adhesion protein, in response to disruption of cell-matrix interaction2009
- Author(s)
  Kauznori Mori, Fumihiro Ishikawa, Kiyoshi Nose, Motoko
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20790263
[Presentation] 細胞接着斑タンパク質Hic-5による接着応答性、細胞死誘導とがん細胞死制御の可能性2008
- Author(s)
  溝手優子、森一憲、野瀬清、柴沼質子
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20790263
[Presentation] 足場依存性増殖制御に関わる細胞接着斑-核シャトルHic-5複合体によるcyclin D1核局在制御機構の解析2008
- Author(s)
  荒木裕理、森一憲、野瀬清、柴沼質子
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20790263
[Presentation] 細胞接着斑蛋白質Hic-5による細胞接着/生存の足場依存性制御機構2008
- Author(s)
  森一憲、野瀬清、柴沼質子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20790263
[Presentation] HIC-5 regulates TGF-b-stimulated MMP-9 expression, anchorage-independent growth, and metastasis of breast cancer cells
- Author(s)
  Kazunori MORI, Fumihiro ISHIKAWA, Motoko SHIBANUMA
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590390

1. SHIBANUMA Motoko (60245876)

# of Collaborated Projects: 11 results

# of Collaborated Products: 47 results
2. ISHIKAWA Fumihiro (60515667)

# of Collaborated Projects: 8 results

# of Collaborated Products: 33 results
3. KANEYAMA Syuri (10338535)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. NOSE Iyoshi (70012747)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
5. EGAWA K. (00095879)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 日暮大渡 (50882487)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 真下順一 (60054045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 西谷直之 (10286867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Mori Kazunori 森 一憲

MORI Kazunori 森 一憲

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転移抑制を目指したRac1によるintegrin β4の分解抑制機構の解明Principal Investigator

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Impact of mitochondrial complex I activity on cancer cell proliferation: importance of NAD+ levelsPrincipal Investigator

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A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS-activated cancer cellsPrincipal Investigator

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Suppressive role of the adaptor protein Hic-5 in anchorage-independent cell growthPrincipal Investigator

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A molecular scaffold HIC-5-and KLF4-dependent mechanism transactivates p21^<Cip1> in response to loss of anchoragePrincipal Investigator

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Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage-dependence of cell growth and survivalPrincipal Investigator

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Mori Kazunori 森一憲

MORI Kazunori 森一憲