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Chiba Tadashige  千葉 忠成

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… Alternative Names

千葉 忠成  チバ タダシゲ

CHIBA Tadashige  千葉 忠成

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Researcher Number 60350138
Affiliation (Current) 2025: 日本歯科大学, 生命歯学部, 准教授
Affiliation (based on the past Project Information) *help 2014 – 2020: 日本歯科大学, 生命歯学部, 准教授
2011 – 2012: 日本歯科大学, 生命歯学部, 准教授
2010: 日本歯科大学, 生命歯学部, 講師
Review Section/Research Field
Principal Investigator
Functional basic dentistry
Except Principal Investigator
Pathobiological dentistry/Dental radiology / Basic Section 57020:Oral pathobiological science-related
Keywords
Principal Investigator
浸潤・転移能 / 発現ベクター / 質量分析 / 細胞増殖能 / MALT1遺伝子 / 細胞周期 / 浸潤 / 細胞増殖 / MALT1 / 癌 … More
Except Principal Investigator
… More 口腔癌 / プロモーター / MALT1 / 浸潤 / ドメイン / Sp1 / 転写因子 / Sp3 / サイレンサー / 口腔癌細胞 / KLF5 / KLF Less
  • Research Projects

    (4 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (5 People)
  •  Nuclear translocation mechanism of MALT1 and oral carcinoma cell invasion

    • Principal Investigator
      Kazushi IMAI
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      The Nippon Dental University
  •  KLF-dependent cell differentiation- and EMT-inducing factor and suppression of oral carcinoma progression

    • Principal Investigator
      Imai Kazushi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      The Nippon Dental University
  •  Functional analysis of the progress suppressor of mucosa-associated lymphoid tissue 1 with oral carcinomasPrincipal Investigator

    • Principal Investigator
      CHIBA Tadashige
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      The Nippon Dental University
  •  Inhibition of NFκB activity by MALT1 and its involvement in phenotypic alterations of oral carcinoma cells

    • Principal Investigator
      IMAI Kazushi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      The Nippon Dental University

All 2021 2020 2019 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

  • [Book] 口腔癌進展のメカニズムと分子標的薬,歯学100(春期特集号)2013

    • Author(s)
      今井一志、須藤遥、前田元太、千葉忠成
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Book] Chapter 7: Cadherin expression and progression of squamous cell carcinomas of the oral cavity. In Squamous Cell Carcinom2012

    • Author(s)
      Imai K, Maeda G, Chiba T
    • Publisher
      Li X,,ed
    • Data Source
      KAKENHI-PROJECT-22592103
  • [Book] Squamous Cell Carcinoma2012

    • Author(s)
      Kazushi Imai, Genta Maeda and Tadashige Chiba
    • Total Pages
      16
    • Publisher
      InTech-Open Science
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Journal Article] NF-kB subunit RELA suppression of mucosa-associated lymphoi tissue lymphoma tranlocation protein 1 expression in oral carcinoma cells2021

    • Author(s)
      Takaomi Nozawa, Nozomi Mihara-Tomiyama, Tadashige Chiba, Kazushi Imai
    • Journal Title

      Biochemistry and Biophysical Research Communications

      Volume: 542 Pages: 24-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09542
  • [Journal Article] Domain structures of mucosa-associated lymphoid tissue lymphoma translocation 1 protein for nuclear translocation in oral carcinoma cells and the proliferation inhibition2020

    • Author(s)
      H Hayashi, T Chiba, N Mihara-Tomiyama, T Negishi, Y Kodama, H Sakashita, K Imai
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 522 Issue: 3 Pages: 799-804

    • DOI

      10.1016/j.bbrc.2019.11.171

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09542
  • [Journal Article] MALT1 Inhibition of Oral Carcinoma Cell Invasion and ERK/MAPK Activation.2016

    • Author(s)
      Chiba T, Soeno Y, Shirako Y, Sudo H, Yagishita H, Taya Y, Kawashiri S, Okada Y, Imai K.
    • Journal Title

      Journal of Dental Research

      Volume: 95 Issue: 4 Pages: 446-452

    • DOI

      10.1177/0022034515621740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670861, KAKENHI-PROJECT-15H05042, KAKENHI-PROJECT-26462859
  • [Journal Article] Krüppel-like factor 4 expression in oral carcinoma cells and hypermethylation at the gene promoter2015

    • Author(s)
      Yamaguchi A, Kuroyama K, Tokura A, Saito A, Arikawa H, Hasebe T, Usui D, Yamaguchi K, Chiba T, Imai K
    • Journal Title

      BMC Oral Health

      Volume: 16 Pages: 13-13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462859
  • [Journal Article] Kruppel-like factors 4 and 5 expression and their involvement in differentiation of oral carcinomas.2015

    • Author(s)
      Shibata M, Chiba T, Matsuoka T, Mihara N, Kawashiri S, Imai K.
    • Journal Title

      Int J Clin Exp Pathol

      Volume: 8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462859
  • [Journal Article] Krüppel-like factors 4 and 5 expression and their involvement in differentiation of oral carcinomas2015

    • Author(s)
      Shibata M, Chiba T, Matsuoka T, Mihara N, Kawashiri S, Imai K
    • Journal Title

      Int. J. Clin. Exp. Pathol.

      Volume: 8 Pages: 3701-3709

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462859
  • [Journal Article] 口腔癌進展のメカニズムと分子標的薬2013

    • Author(s)
      今井一志、須藤遥、前田元太、千葉忠成
    • Journal Title

      歯学

      Volume: 100 Pages: 177-181

    • Data Source
      KAKENHI-PROJECT-22592103
  • [Journal Article] Inhibition of TGF-beta and EGF pathway gene expression and migration of oral carcinoma cells by mucosa-associated lymphoid tissue 1.

    • Author(s)
      Ohyama Y, Kawamoto H, Chiba T, Maeda G, Sakashita H, Imai K
    • Journal Title

      British J cancer

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22592080
  • [Journal Article] Inhibition of TGF- and EGF pathway gene expression and migration of oral carcinoma cells by mucosa-associated lymphoid tissue 1.

    • Author(s)
      Ohyama Y, Kawamoto Y, Chiba T, Maeda G, Sakashita H, Imai K
    • Journal Title

      Br J Cancer

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592103
  • [Journal Article] Proteomic identification of keratin alterations with enhanced proliferation of oral carcinoma cells by loss of mucosa-associated lymphoid tissue 1 expression

    • Author(s)
      Kawamoto H, Ohyama Y, Chiba T, Yagishita H, Sakashita H, Imai K
    • Journal Title

      Int J Oncol

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 口腔癌細胞におけるMALT1核移行ドメインの解析2019

    • Author(s)
      林宏泰、千葉忠成、冨山希美、今井一志、坂下英明
    • Organizer
      第73回NPO法人日本口腔科学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K09542
  • [Presentation] 口腔癌細胞におけるKruppel-like factor 4発現とプロモーターのメチル化2015

    • Author(s)
      山口光祐,千葉忠成,美原希美,須藤遥,今井一志
    • Organizer
      第57回日本歯科基礎医学会学術大会・総会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26462859
  • [Presentation] Kruppel-like factor 5遺伝子のプロモーター解析2014

    • Author(s)
      美原希美、千葉忠成、須藤遥、今井一志
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-26462859
  • [Presentation] Profiling and network analysis of MALT1-responsive gene datasets in SCC,PROGRAM BOOK2013

    • Author(s)
      Ohyama Y,Kawamoto H,Chiba T,Maeda G, Sakashita H,Imai K
    • Organizer
      91th IADR/AADR/CADR General Session and Exhibition,p.X (No. 1459)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] MALT1-responsive keratin rearrangement and proliferation of oral carcinoma cells,PROGRAM BOOK2013

    • Author(s)
      Kawamoto H,Ohyama Y,Chiba T,YagishitaH,Sakashita H,Imai K
    • Organizer
      91th IADR/AADR/CADR General Session and Exhibition,p.X (No. 2711)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] Profiling and network analysis of MALT1-responsive gene datasets in SCC.2013

    • Author(s)
      Ohyama Y, Kawamoto H, Chiba T, Maeda G, Sakashita H, Imai K.
    • Organizer
      IADR/AADR/CADR General Session and Exhibition
    • Place of Presentation
      Seattle,WA,USA
    • Data Source
      KAKENHI-PROJECT-22592103
  • [Presentation] MALT1-responsive keratin rearrangement and proliferation of oral carcinoma cells.2013

    • Author(s)
      Kawamoto H, Ohyama Y, Chiba T, Yagishita H, Sakashita H, Imai K.
    • Organizer
      IADR/AADR/CADR General Session and Exhibition
    • Place of Presentation
      Seattle, WA,USA
    • Data Source
      KAKENHI-PROJECT-22592103
  • [Presentation] 口腔癌細胞はMALT1 によりケ ラチンの発現と増殖能を変動する2012

    • Author(s)
      川本幸寛、大山嘉人、千葉忠成、坂下英 明、今井一志
    • Organizer
      J Oral Biosci,Suppl:109 (No. P1-9)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 口腔癌の進展におけるMALT1の機能2012

    • Author(s)
      千葉忠成, 川本幸寛, 大山嘉人, 今井一志
    • Organizer
      日本歯科大学学会研究推進フォーラム
    • Place of Presentation
      千代田区、日本歯科大学
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] Progression/metastasis of xenografted oral cancer cell-lines in mouse tongue.2012

    • Author(s)
      Soeno Y, Shirako Y, Fujita K, Taya Y, Shimazu Y, Nakau K, Sato K, Chiba T, ImaiK,AobaT
    • Organizer
      41st Annual Meeting & Exhibition of the AADR
    • Place of Presentation
      Tampa,FL,USA
    • Data Source
      KAKENHI-PROJECT-22592103
  • [Presentation] 口腔癌の進展にはカドヘリンスイ ッチではなく、E-カドヘリンの発現低下が関連する2012

    • Author(s)
      橋本孝志、添野雄一、田谷雄二、青葉孝 昭、那須優則、前田元太、須藤遥、千葉忠成、 今井一志
    • Organizer
      J Oral Biosci,Suppl:137 (No.P1-120)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 口腔癌細胞におけるMALT1 誘 導性遺伝子のマイクロアレイ解析2012

    • Author(s)
      大山嘉人、川本幸寛、千葉忠成、坂下英明、今井一志
    • Organizer
      第85回 日本生化学会大会プログラム・抄録集, Suppl:115 (2P-682)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] Epigenetic loss ofmucosa-associated lymphoid tissue 1 expression in patients with oral carcinoma2012

    • Author(s)
      Chiba T,Maeda G,Kawashiri S,Kato K, Imai K
    • Organizer
      Japan China Dental Conference 2012, Suppl:18 (No. 0407)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 関節リウマチ滑膜線維芽細胞様細2012

    • Author(s)
      山崎典孝、須藤遥、前田元太、千葉忠成、今井一志
    • Organizer
      J Oral Biosci,Suppl:166 (No. P2-113)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 口腔扁平上皮癌細胞における MALT1. 誘導タンパク質のプロテオーム解析2012

    • Author(s)
      川本幸寛, 大山嘉人, 千葉忠成, 坂下英明, 今井一志
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岐阜市、長良川国際会議場
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] ヒト扁平上皮癌モデルにおける解析2012

    • Author(s)
      添野雄一, 白子要一, 藤田和也, 田谷雄二, 島津徳人, 中右かよ, 佐藤かおり, 千葉忠成, 今井一志, 青葉孝昭
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜市、パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] Progression/metastasis of xenografted oral cancer cell-lines in mouse tongue.2012

    • Author(s)
      Y. Soeno, Y. Shirako, K. Fujita, Y. Taya, Y. Shimazu, K. Nakau, K. Sato, T. Chiba, K. Imai, T. Aoba.
    • Organizer
      41st Annual Meeting & Exhibition of the AADR, March 21-24
    • Place of Presentation
      Tampa, FL, USA.
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 口腔癌におけるp120カテニンとβカテニン発現の免疫組織学的解析2012

    • Author(s)
      笹谷和伸、前田元太、須藤遥、千葉忠成、今井一志
    • Organizer
      第54回歯科基礎医学会学術大会・総会
    • Place of Presentation
      郡山市
    • Year and Date
      2012-09-15
    • Data Source
      KAKENHI-PROJECT-22592103
  • [Presentation] 口腔癌の進展にはカドヘリンスイッチではなく、E-カドヘリンの発現低下が関連する2012

    • Author(s)
      橋本孝志、添野雄一、田谷雄二、青葉孝昭、那須優則、前田元太、須藤遥、千葉忠成、今井一志
    • Organizer
      第54回歯科基礎医学会学術大会・総会
    • Place of Presentation
      郡山市
    • Year and Date
      2012-09-15
    • Data Source
      KAKENHI-PROJECT-22592103
  • [Presentation] ヒト舌扁平上皮癌におけるCadherin Switchと細胞形質変化2012

    • Author(s)
      添野雄一, 田谷雄二, 島津徳人, 藤田和也, 佐藤かおり, 千葉忠成, 今井一志, 青葉孝昭
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岐阜市、長良川国際会議場
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 口腔癌におけるp120 カテニンとβ カテニン発現の免疫組織学的解析2012

    • Author(s)
      笹谷和伸、前田元太、須藤遥、千葉忠成、 今井一志
    • Organizer
      J Oral Biosci,Suppl:136 (No. P1-119)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] MALT1 による口腔癌細胞の変動タンパク 質と増殖能について2012

    • Author(s)
      川本幸寛、大山嘉人、瀧澤将太、横塚裕 二、篠原優紀、福田正勝、千葉忠成、坂下英明
    • Organizer
      第57回日本口腔外科 学会プログラム・抄録集,Suppl:115 (No.D3-2)
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] ヒト扁平上皮癌モデルにおける解析2011

    • Author(s)
      添野雄一、白子要一、藤田和也、田谷雄 二、島津徳人、中右かよ、佐藤かおり、千葉 忠成、今井一志、青葉孝昭 腫瘍微小環境と 浸潤転移能
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜市.
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 口腔扁平上皮癌細胞におけるMALT1誘導タンパク質のプロテオーム解析2011

    • Author(s)
      川本幸寛、大山嘉人、千葉忠成、坂下英明、今井一志
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岐阜市
    • Data Source
      KAKENHI-PROJECT-22592103
  • [Presentation] 口腔癌の進展におけるMALT1 の機能2011

    • Author(s)
      千葉忠成、川本幸寛、大山嘉人、今井一 志
    • Organizer
      日本歯科大学歯学会研究推進フォーラム
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] ヒト舌扁平上皮癌におけるCadherinSwitchと細胞形質変化2011

    • Author(s)
      添野雄一、田谷雄二、島津徳人、藤田和也、佐藤かおり、千葉忠成、今井一志、青葉孝昭
    • Organizer
      第53回歯科基礎医学会学術大会・総会 J Oral Biosci、53Suppl:pp.197
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] 口腔扁平上皮癌細胞における MALT1 誘導タンパク質のプロテオーム解析2011

    • Author(s)
      川本幸寛、大山嘉人、千葉忠成、坂下英明、今井一志
    • Organizer
      第53回歯科基礎医学会学術大会・総会 J Oral Biosci、53(Suppl):pp.124
    • Data Source
      KAKENHI-PROJECT-22592080
  • [Presentation] Promoter analysis of Kruppel-like factor 5 gene.

    • Author(s)
      Mihara N, Chiba T, Sudo H, Imai K
    • Organizer
      General Session and Exhibition of the IADR
    • Place of Presentation
      ボストン(米国)
    • Year and Date
      2015-03-11 – 2015-03-14
    • Data Source
      KAKENHI-PROJECT-26462859
  • 1.  IMAI Kazushi (10328859)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 18 results
  • 2.  MIHARA Nozomi (00803264)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 3.  MORIKAWA Masako (80095265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  須藤 遙 (20372980)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  川尻 秀一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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