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Ushiku Tetsuo  牛久 哲男

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USHIKU Tetsuo  牛久 哲男

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Researcher Number 60376415
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院医学系研究科(医学部), 教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 東京大学, 大学院医学系研究科(医学部), 教授
2016 – 2018: 東京大学, 大学院医学系研究科(医学部), 准教授
2015: 東京大学, 医学(系)研究科(研究院), 准教授
2011 – 2013: 東京大学, 医学部附属病院, 助教
2007 – 2008: The University of Tokyo, 医学部附属病院, 助教 … More
2007: The University of Tokyo, Hospital, Research Associate
2006: 東京大学, 医学部附属病院, 助手
2004: 東京大学, 大学院・医学研究科, 助手
2004: The University of Tokyo, Graduate School of Medicine, Research Associate, 大学院・医学系研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 49020:Human pathology-related / Human pathology
Except Principal Investigator
Human pathology / Basic Section 90130:Medical systems-related / Broad Section I / Medium-sized Section 20:Mechanical dynamics, robotics, and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related / Human pathology
Keywords
Principal Investigator
胃癌 / 胎児形質 / 免疫回避機構 / 治療標的 / SALL4 / AFP / 胎児型形質 / 悪性度 / ゲノム異常 / 治療標的分子 … More / 免疫回避 / 高悪性度 / 分子標的 / 腫瘍免疫回避機構 / ARHGAPs / RHOA / CLDN6 / Glypican-3 / Claudin-6 / 分子分類 / びまん型胃癌 / 肝転移 / Glypican3 / Epstein-Barrウイルス / Glypican 3 / Glypican 3, Epstein-Barr ウイルス / 内視鏡治療 / 早期胃癌 … More
Except Principal Investigator
胃癌 / 胃癌細胞株 / EBウイルス / EBウイルス関連胃癌 / promoter / gastric carcinoma / プロモーター / 組織損傷 / 低侵襲手術 / 治療デバイス / 膵液漏 / 手術支援ロボット / 低侵襲手術支援デバイス / コンピュータ外科 / ゲノム / 病理画像 / 人工知能 / 自動化 / 切断 / 病理 / AI / 遠隔操作 / ロボット / 断端 / 癌 / 蛍光 / 手術 / 前立腺 / gastric carcinoma cell line / carcinogenesis / DNA methylation / infectious agent and host interaction / Epstein-Barr virus / EBV-associated gastric carcinoma / 発癌 / DNAメチル化 / 病原体・宿主相互作用 / AIDS lymphoma / methylation / genetic polymorphism / interleukin 1-b / pyothorax-associated lymphoma / EB virus / プロモーター領域 / SCIDマウス移植株 / 遺伝子発現プロファイル / DNAチップ / アポトーシス / IL1-β / EBウイルス関連腫瘍 / AIDSリンパ腫 / メチル化 / 遺伝子多型 / インターロイキン1-β / 膿胸関連リンパ腫 / 上皮間葉転換 / miR200 / RRM2 / 転写因子 / STAT3 / DNMT1 / エクソソーム / 幹細胞 / マイクロRNA / トランスジェニックマウス / SP細胞 / LMP2A / エピジェネティクス Less
  • Research Projects

    (13 results)
  • Research Products

    (96 results)
  • Co-Researchers

    (49 People)
  •  Molecular characterization of gastric carcinoma with a primitive phenotypePrincipal Investigator

    • Principal Investigator
      牛久 哲男
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      The University of Tokyo
  •  A New Definition of Gastric Cancer Diversity through Quantitative Integration of histological and Genomic Information

    • Principal Investigator
      石川 俊平
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      The University of Tokyo
  •  組織破壊特性を考慮した膵液漏防止ステープラーデバイスの研究

    • Principal Investigator
      小林 英津子
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      The University of Tokyo
  •  Fluorescent Substrates for Cancer Detection Using Clinical Specimens and Animal Models Aiming for Negative Margin of Prostate Cancer Surgery

    • Principal Investigator
      山田 大介
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      The University of Tokyo
  •  Molecular characterization and therapeutic target identification of gastric cancer with primitive phenotypePrincipal Investigator

    • Principal Investigator
      Ushiku Tetsuo
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      The University of Tokyo
  •  Autonomous pathology grossing robot

    • Principal Investigator
      光石 衛
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 20:Mechanical dynamics, robotics, and related fields
    • Research Institution
      Teikyo University
      The University of Tokyo
  •  Clinicopathological and molecular analyses of primitive phenotypic transformation in cancer developmentPrincipal Investigator

    • Principal Investigator
      Ushiku Tetsuo
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      The University of Tokyo
  •  Pathological and molecular characterization of gastric cancer with aggressive phenotypePrincipal Investigator

    • Principal Investigator
      Ushiku Tetsuo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  Clinicopathologic features of gastric cancer associated with liver metastasisPrincipal Investigator

    • Principal Investigator
      USHIKU Tetsuo
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  EB virus-associated gastric carcinoma. Molecular mechanisms of DNA hypermethylation and strategy for gastric cancer therapy.

    • Principal Investigator
      FUKAYAMA Masashi
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  Histopathologic analysis of early gastric cancer to establish better criteria for endoscopic treatment.Principal Investigator

    • Principal Investigator
      USHIKU Tetsuo
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  Carcinogenesis of EB virus-associated gastric carcinoma. Mutual DNA-methylation of host and infective agent.

    • Principal Investigator
      FUKAYAMA Masashi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  Pathogenesis of EB virus-associated neoplasms

    • Principal Investigator
      FUKAYAMA Masashi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Other

  • [Book] 癌の分子病理学(分担)2016

    • Author(s)
      牛久哲男
    • Total Pages
      349
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Book] 病理診断クイックリファレンス(分担)2015

    • Author(s)
      牛久哲男
    • Total Pages
      355
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Book] 腫瘍病理鑑別診断アトラス「胃癌」第2版(分担)2015

    • Author(s)
      牛久哲男
    • Total Pages
      318
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Journal Article] Pathology and Clinical Relevance of Gastric Epithelial Dysplasia2024

    • Author(s)
      Ushiku Tetsuo、Lauwers Gregory Y.
    • Journal Title

      Gastroenterology Clinics of North America

      Volume: 53 Issue: 1 Pages: 39-55

    • DOI

      10.1016/j.gtc.2023.11.003

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Journal Article] Stomach encyclopedia: Combined single-cell and spatial transcriptomics reveal cell diversity and homeostatic regulation of human stomach2023

    • Author(s)
      Tsubosaka Ayumu、Komura Daisuke、Kakiuchi Miwako、Katoh Hiroto、Onoyama Takumi、Yamamoto Asami、Abe Hiroyuki、Seto Yasuyuki、Ushiku Tetsuo、Ishikawa Shumpei
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 10 Pages: 113236-113236

    • DOI

      10.1016/j.celrep.2023.113236

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ1012, KAKENHI-PROJECT-21K06882, KAKENHI-PROJECT-22H04990, KAKENHI-PROJECT-19H01032
  • [Journal Article] Aberrant Cadherin11 expression predicts distant metastasis of gastric cancer2023

    • Author(s)
      Mita Hideaki, Katoh Hiroto, Komura Daisuke, Kakiuchi Miwako, Abe Hiroyuki, Rokutan Hirofumi, Yagi Koichi, Nomura Sachiyo, Ushiku Tetsuo, Seto Yasuyuki, Ishikawa Shumpei.
    • Journal Title

      Pathology - Research and Practice

      Volume: 242 Pages: 154294-154294

    • DOI

      10.1016/j.prp.2022.154294

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-22H04990, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-20KK0174, KAKENHI-ORGANIZER-22H05021
  • [Journal Article] Restaining-based annotation for cancer histology segmentation to overcome annotation-related limitations among pathologists.2023

    • Author(s)
      Komura D, Onoyama T, Shinbo K, Odaka H, Hayakawa M, Ochi M, Herdiantoputri RR, Endo H, Katoh H, Ikeda T, Ushiku T, Ishikawa S.
    • Journal Title

      Patterns

      Volume: 4(2) Issue: 2 Pages: 100688-100688

    • DOI

      10.1016/j.patter.2023.100688

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H04990, KAKENHI-PROJECT-23K21859
  • [Journal Article] Carcinosarcoma of the stomach: four cases that expand the morphologic spectrum of gastric cancer with a primitive phenotype2022

    • Author(s)
      Yamazawa Sho、Ushiku Tetsuo
    • Journal Title

      Virchows Archiv

      Volume: 480 Issue: 5 Pages: 1051-1062

    • DOI

      10.1007/s00428-022-03307-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K16581, KAKENHI-PROJECT-21K06882
  • [Journal Article] 高悪性度胃癌の分子病理学的特徴2022

    • Author(s)
      牛久哲男
    • Journal Title

      胃と腸

      Volume: 57 Pages: 434-439

    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Journal Article] Cross-species chromatin interactions drive transcriptional rewiring in Epstein-Barr virus-positive gastric adenocarcinoma2020

    • Author(s)
      Okabe Atsushi, Huang Kie Kyon, Matsusaka Keisuke, Fukuyo Masaki, Xing Manjie, Ong Xuewen, Hoshii Takayuki, Usui Genki, Seki Motoaki, Mano Yasunobu, Rahmutulla Bahityar, Kanda Teru, Suzuki Takayoshi, Rha Sun Young, Ushiku Tetsuo, Fukayama Masashi, Tan Patrick, Kaneda Atsushi
    • Journal Title

      Nature Genetics

      Volume: 52 Issue: 9 Pages: 919-930

    • DOI

      10.1038/s41588-020-0665-7

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K09184, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03690, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-18J00861, KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-19K22399, KAKENHI-PROJECT-19K16101
  • [Journal Article] Defined lifestyle and germline factors predispose Asian populations to gastric cancer2020

    • Author(s)
      Suzuki A, Katoh H, Komura D, Kakiuchi M, Tagashira A, Yamamoto S, Tatsuno K, Ueda H, Nagae G, Fukuda S, Umeda T, Totoki Y, Abe H, Ushiku T, Matsuura T, Sakai E, Ohshima T, Nomura S, Seto Y, Shibata T, Rino Y, Nakajima A, Fukayama M, Ishikawa S, Aburatani H.
    • Journal Title

      Science Advances

      Volume: 6 Issue: 19 Pages: 9778-9778

    • DOI

      10.1126/sciadv.aav9778

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-17K07195, KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-18K07963, KAKENHI-PROJECT-16H02481
  • [Journal Article] DNA Methylation and Genetic Aberrations in Gastric Cancer2020

    • Author(s)
      Usui Genki、Matsusaka Keisuke、Mano Yasunobu、Urabe Masayuki、Funata Sayaka、Fukayama Masashi、Ushiku Tetsuo、Kaneda Atsushi
    • Journal Title

      Digestion

      Volume: 102 Issue: 1 Pages: 25-32

    • DOI

      10.1159/000511243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21625, KAKENHI-PROJECT-18J00861, KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-20K16166
  • [Journal Article] Programmed cell death protein 1/programmed death ligand 1 but not HER2 is a potential therapeutic target in gastric neuroendocrine carcinoma2020

    • Author(s)
      Yamashita Satoshi、Abe Hiroyuki、Kunita Akiko、Yamashita Hiroharu、Seto Yasuyuki、Ushiku Tetsuo
    • Journal Title

      Histopathology

      Volume: 78 Issue: 3 Pages: 381-391

    • DOI

      10.1111/his.14230

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07422, KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-18K07012
  • [Journal Article] Initial and crucial genetic events in intestinal-type gastric intramucosal neoplasia2019

    • Author(s)
      Rokutan Hirofumi、Abe Hiroyuki、Nakamura Hiromi、Ushiku Tetsuo、Arakawa Erika、Hosoda Fumie、Yachida Shinichi、Tsuji Yosuke、Fujishiro Mitsuhiro、Koike Kazuhiko、Totoki Yasushi、Fukayama Masashi、Shibata Tatsuhiro
    • Journal Title

      The Journal of Pathology

      Volume: 247 Issue: 4 Pages: 494-504

    • DOI

      10.1002/path.5208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-18K15229
  • [Journal Article] Adenocarcinoma of the esophagogastric junction and its background mucosal pathology: A comparative analysis according to Siewert classification in a Japanese cohort2018

    • Author(s)
      Urabe Masayuki、Ushiku Tetsuo、Shinozaki-Ushiku Aya、Iwasaki Akiko、Yamazawa Sho、Yamashita Hiroharu、Seto Yasuyuki、Fukayama Masashi
    • Journal Title

      Cancer Medicine

      Volume: 7 Issue: 10 Pages: 5145-5154

    • DOI

      10.1002/cam4.1763

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-17K19673
  • [Journal Article] Frequent <i>CLDN18-ARHGAP</i> fusion in highly metastatic diffuse-type gastric cancer with relatively early onset2018

    • Author(s)
      Tanaka Atsushi、Ishikawa Shumpei、Ushiku Tetsuo、Yamazawa Sho、Katoh Hiroto、Hayashi Akimasa、Kunita Akiko、Fukayama Masashi
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 50 Pages: 29336-50

    • DOI

      10.18632/oncotarget.25464

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-17K15611, KAKENHI-PROJECT-17K15636, KAKENHI-PROJECT-26253021
  • [Journal Article] Gastric cancer with primitive enterocyte phenotype: an aggressive subgroup of intestinal-type adenocarcinoma2017

    • Author(s)
      Yamazawa S, Ushiku T, Shinozaki-Ushiku A, Hayashi A, Iwasaki A, Abe H, Tagashira A, Yamashita H, Seto Y, Aburatani H, Fukayama M
    • Journal Title

      American Journal of Surgical Pathology

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Journal Article] 胚細胞腫瘍に類似した体細胞腫瘍の組織発生と分化2017

    • Author(s)
      牛久哲男、山澤翔、深山正久
    • Journal Title

      病理と臨床

      Volume: 35 Pages: 1126-1132

    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Journal Article] Gastric Cancer With Primitive Enterocyte Phenotype: An Aggressive Subgroup of Intestinal-type Adenocarcinoma.2017

    • Author(s)
      Yamazawa S, Ushiku T, Shinozaki-Ushiku A, Hayashi A, Iwasaki A, Abe H, Tagashira A, Yamashita H, Seto Y, Aburatani H, Fukayama M.
    • Journal Title

      Am J Surg Pathol

      Volume: 41 Issue: 7 Pages: 989-997

    • DOI

      10.1097/pas.0000000000000869

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-15K08340
  • [Journal Article] RHOA mutation in diffuse-type gastric cancer: a comparativeclinicopathology analysis of 87 cases.2016

    • Author(s)
      Ushiku T, Ishikawa S, Kakiuchi M, Tanaka A, Katoh H, Aburatani H, Lauwers GY, Fukayama M.
    • Journal Title

      Gastric Cancer

      Volume: 19 Issue: 2 Pages: 403-411

    • DOI

      10.1007/s10120-015-0493-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08340, KAKENHI-PROJECT-24221011
  • [Journal Article] Pathologic response of HER2-positive gastric cancer to Trastuzumab-based chemotherapy.2016

    • Author(s)
      Urabe M, Ushiku T, Seto Y, Fukayama M
    • Journal Title

      Am J Surg Pathol

      Volume: 40 Issue: 10 Pages: 1326-1333

    • DOI

      10.1097/pas.0000000000000672

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-15K08340
  • [Journal Article] 癌の分子病理診断の現状と将来・胃癌2016

    • Author(s)
      牛久哲男
    • Journal Title

      病理と臨床

      Volume: 34 Pages: 280-286

    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Journal Article] 胎児消化管上皮類似癌2016

    • Author(s)
      牛久哲男
    • Journal Title

      病理と臨床

      Volume: 34 Pages: 954-958

    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Journal Article] Very well-differentiated gastric carcinoma of intestinal type analysis of diagnostic criteria2013

    • Author(s)
      Ushiku T, Arnason T, Ban S, Hishima T, Shimizu M, Fukayama M, Lauwers GY.
    • Journal Title

      Modern Pathology.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790390
  • [Journal Article] Distinct expression pattern of claudin-6, a primitive phenotypic tight junction molecule, in germ cell tumours and visceral carcinomas.2012

    • Author(s)
      Ushiku T, Shinozaki-Ushiku A, Maeda D, Morita S, Fukayama M.
    • Journal Title

      Histopathology.

      Volume: 61(6) Issue: 6 Pages: 1043-56

    • DOI

      10.1111/j.1365-2559.2012.04314.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790390
  • [Journal Article] 専門医のためのアトラス EBV関連胃癌2011

    • Author(s)
      牛久哲男、深山正久
    • Journal Title

      胃癌perspective

      Volume: 4(4) Pages: 260-264

    • Data Source
      KAKENHI-PROJECT-23790390
  • [Journal Article] Transcriptional factor typing with SOX2, HNF4aP1, and CDX2 closely relates to tumor invasion and Epstein-Barr virus status in gastric cancer2011

    • Author(s)
      Uozaki H, Barua RR, Minhua S, Ushiku T, Hino R, Shinozaki A,Sakatani T, Fukayama M
    • Journal Title

      International Journal of Clinicaland Experimental Pathology

      Volume: Vol.4 Pages: 230-240

    • URL

      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071656/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] 専門医のためのアトラスEBV関連胃癌2011

    • Author(s)
      牛久哲男, 深山正久
    • Journal Title

      胃がんperspective

      Volume: 4 Pages: 260-264

    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] Epstein-Barr virus-associated gastric carcinoma.Pathology2011

    • Author(s)
      Fukayama M, Ushiku T
    • Journal Title

      Research and Practice

      Volume: Vol.207 Issue: 9 Pages: 529-53

    • DOI

      10.1016/j.prp.2011.07.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022, KAKENHI-PROJECT-23790390
  • [Journal Article] Gastric carcinoma with invasive micropapillary pattern and its association with node metastasis.2011

    • Author(s)
      Ushiku T, Matsusaka K, Iwasaki Y,Tateishi Y, Funata N, Seto Y,Fukayama M.
    • Journal Title

      Histopathology.

      Volume: 59(6) Issue: 6 Pages: 1081-89

    • DOI

      10.1111/j.1365-2559.2011.04055.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790390
  • [Journal Article] Gastric carcinoma with osteoclast-like giant cells. Lymphoepithelioma-like carcinoma with Epstein-Barr virus infection is the predominant type.2010

    • Author(s)
      Ushiku T, et al.
    • Journal Title

      Pathology International

      Volume: 60 Pages: 551-558

    • NAID

      10030720996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] Downregulation of microRNA-200 in EBV-associated gastric carcinoma2010

    • Author(s)
      Shinozaki A, Sakatani T, Ushiku T, Hino R, Isogai M, Ishikawa S, Uozaki H, Takada K, Fukayama M
    • Journal Title

      Cancer Research

      Volume: Vol.70 Issue: 11 Pages: 4719-4727

    • DOI

      10.1158/0008-5472.can-09-4620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] Downregulation of microRNA-200 in EBV-associated gastric carcinoma.2010

    • Author(s)
      Shinozaki A, Sakatani T, Ushiku T, Hino R, Isogai M, Ishikawa S, Uozaki H, Takada K, Fukayama M.
    • Journal Title

      Cancer Research. 70巻

      Pages: 4719-4727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] Expression of ribonucleotide reductase M2subunit in gastric cancer and effects of RRM2 inhibition in vitro2010

    • Author(s)
      Morikawa T, Hino R, Uozaki H, Maeda D, Ushiku T, Shinozaki A,Sakatani T, Fukayama M
    • Journal Title

      Human Pathology

      Volume: Vol.41 Issue: 12 Pages: 1742-1748

    • DOI

      10.1016/j.humpath.2010.06.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022, KAKENHI-PROJECT-22890037
  • [Journal Article] Prominent Mott cell proliferation in Epstein-Barr virus-associated gastric carcinoma2010

    • Author(s)
      Shinozaki A, Ushiku T, Fukayama M
    • Journal Title

      Human Pathology

      Volume: Vol.41 Issue: 1 Pages: 134-138

    • DOI

      10.1016/j.humpath.2009.07.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] 特殊な成り立ちの早期胃癌1)Epstein-Barr virus関連胃癌2009

    • Author(s)
      牛久哲男
    • Journal Title

      胃と腸 44

      Pages: 723-729

    • Data Source
      KAKENHI-PROJECT-19790251
  • [Journal Article] Epstein-Barr virus関連胃癌.2009

    • Author(s)
      牛久哲男, 他
    • Journal Title

      胃と腸 44

      Pages: 723-729

    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] Glypican 3-expressing gastric carcinoma : Distinct subgroup unifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomas.2009

    • Author(s)
      Tetsuo Ushiku, et.al.
    • Journal Title

      Cancer Sci 100

      Pages: 626-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790251
  • [Journal Article] Epstein-Barr virus-associated gastric carcinoma : a distinct carcinoma of gastric phenotype by claudin expression profiling.2009

    • Author(s)
      Shinozaki A, Ushiku T, Morikawa T, HinoR, Sakatani T, Uozaki H, Fukayama M.
    • Journal Title

      Journal of Histochemistry and Cytochemistry. 57巻

      Pages: 75-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] Glypican 3-expressing gastric carcinoma : Distinct subgroup u nifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomas2009

    • Author(s)
      Tetsuo Ushiku
    • Journal Title

      Cancer Science

      Pages: 626-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790251
  • [Journal Article] 特殊な成り立ちの早期胃癌 1) Epstein-Barr virus 関連胃癌2009

    • Author(s)
      牛久哲男, 他2名
    • Journal Title

      胃と腸

      Pages: 44-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790251
  • [Journal Article] Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinoma.2009

    • Author(s)
      Hino R, Uozaki H, Murakami N, Ushiku T, Shinozaki A, Ishikawa S, Morikawa T, Nakaya T, Sakatani T, Takada K, Fukayama M.
    • Journal Title

      Cancer Research. 69巻

      Pages: 2766-2774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Journal Article] P73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma2007

    • Author(s)
      Ushiku T, et. al.
    • Journal Title

      International Journal of Cancer 120

      Pages: 60-66

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390110
  • [Journal Article] p73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma.2007

    • Author(s)
      Ushiku T, et. al.
    • Journal Title

      International Journal of Cancer 120

      Pages: 60-66

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390110
  • [Journal Article] p73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma2007

    • Author(s)
      Ushiku T, et. al.
    • Journal Title

      Int J Cancer 120

      Pages: 60-66

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390110
  • [Presentation] 胃癌診療におけるバイオマーカーの基礎2024

    • Author(s)
      牛久哲男
    • Organizer
      第96回日本胃癌学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Presentation] 胃癌・食道がんにおけるPD-L1 検査2024

    • Author(s)
      牛久哲男
    • Organizer
      第113回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Presentation] 知っておきたい!胃がんBiomarkerの基礎知識 ~Her2からClaudin18.2まで~2023

    • Author(s)
      牛久哲男
    • Organizer
      第95回日本胃癌学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Presentation] 病理検体切り出し動作の計測と分析2023

    • Author(s)
      山下樹里, 鎮西清行, 小関義彦, 金子伸行, 日向宗利, 牛久哲男, 牛久哲男, 原田香奈子, 光石衛
    • Organizer
      日本コンピュータ外科学会
    • Data Source
      KAKENHI-PROJECT-20H00227
  • [Presentation] 胎児形質胃がんのクロマチンアクセシビリティ解析2023

    • Author(s)
      鯉沼 代造, 山本 周, 牛久 哲男
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Presentation] ヒト正常及び腸上皮化生胃粘膜のシングルセルRNA-seqと空間転写解析の統合的解析2023

    • Author(s)
      坪坂歩、垣内美和子、河村大輔、加藤洋人、牛久哲男、石川俊平
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22H04990
  • [Presentation] 病理検体切り出し作業の自動化のための切除力の最適化2023

    • Author(s)
      光石衛, 森公平, 原田香奈子, MARINHO Murilo Marques, 鎮西清行, 小関義彦, 山下樹里, 牛久哲男, 牛久哲男, 金子伸行, 日向宗利
    • Organizer
      日本コンピュータ外科学会
    • Data Source
      KAKENHI-PROJECT-20H00227
  • [Presentation] ゲノム医療の基礎と実際2023

    • Author(s)
      牛久哲男
    • Organizer
      第95回日本胃癌学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Presentation] 症例から学び、最先端に触れ、病理医の力を発揮する腫瘍病理学研究2023

    • Author(s)
      牛久哲男
    • Organizer
      第111回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Presentation] 胎児形質胃癌のアクセシブルクロマチン領域の解析2023

    • Author(s)
      岡本なつめ,鯉沼代造,山本周,九嶋亮治,牛久哲男
    • Organizer
      第112回 日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Presentation] PD-L1 Testing in Gastric Cancer2023

    • Author(s)
      牛久哲男
    • Organizer
      第20回日本臨床腫瘍学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06882
  • [Presentation] 同一標本に対するH&E染色と免疫染色を利用した細胞セグメンテーションのための癌病理組織像データセットの開発2022

    • Author(s)
      河村大輔, 斧山匠, 新保幸輝, 小高滉人, 遠藤春哉, 越智三枝子, 加藤洋人, 牛久哲男, & 石川俊平
    • Organizer
      第68回日本病理学会 秋季特別総会
    • Data Source
      KAKENHI-PROJECT-22H04990
  • [Presentation] ディープラーニングを用いた細胞セグメンテーションのための癌病理組織画像データセット.2022

    • Author(s)
      河村大輔, 斧山巧, 新保幸輝, 小高滉人, 遠藤春哉, 越智三枝子, 加藤洋人, 牛久哲男, & 石川俊平
    • Organizer
      The 81st Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-22H04990
  • [Presentation] 多種染色条件および撮像媒体による多彩な色調を呈するH&E染色病理組織画像データセットの構築.2022

    • Author(s)
      越智三枝子, 河村大輔, 斧山巧, 新保幸輝, 小高滉人, 遠藤春哉, 牛久哲男, & 石川俊平
    • Organizer
      The 81st Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-22H04990
  • [Presentation] Towards Automation and Optimization of Robotic Cutting for Pathology Grossing2021

    • Author(s)
      Hung-Ching Lin, Murilo Marques Marinho, Munetoshi Hinata, Kunihiko Kaneko, Tetsuo Ushiku, Juli Yamashita, Kiyoyuki Chinzei, Mamoru Mitsuishi, Kankako Harada
    • Organizer
      The 17th Asian Conference on Computer Aided Surgery
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00227
  • [Presentation] Pathology of the gastric cancer; WHO classification “Special subtypes of gastric cancer”2020

    • Author(s)
      牛久哲男
    • Organizer
      第92回日本胃癌学会総会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] 病理切り出し作業の自動化に向けた,FEM解析およびその応用に関する研究2020

    • Author(s)
      森公平, 野田清敬, ブエンディーア ジャンレイン マグノ, マルケス・マリニョ ムリロ, 原田香奈子, 日向宗利, 金子伸行, 牛久哲男, 光石衛
    • Organizer
      日本機械学会ロボティクス・メカトロニクス講演会
    • Data Source
      KAKENHI-PROJECT-20H00227
  • [Presentation] 病理切り出し作業の自動化に向けた柔軟物体の切断方法とその影響に関する研究2020

    • Author(s)
      森公平, マルケス・マリニョ ムリロ, 原田香奈子, 日向宗利, 金子伸行, 牛久哲男, 光石衛
    • Organizer
      第29回日本コンピュータ外科学会大会
    • Data Source
      KAKENHI-PROJECT-20H00227
  • [Presentation] AFP産生胃癌におけるHLA-G発現の検討.2020

    • Author(s)
      深澤京, 山澤翔, 岩﨑晶子, 国田朱子, 牛久綾, 牛久哲男.
    • Organizer
      第109回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] Precision treatment for gastric cancer in the era of genomic medicine “Precision treatment for early gastric cancer”2020

    • Author(s)
      牛久哲男
    • Organizer
      第92回日本胃癌学会総会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] 胎児型形質胃癌2019

    • Author(s)
      牛久哲男
    • Organizer
      第108回 日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] 免疫チェックポイント阻害薬時代の消化管病理学2019

    • Author(s)
      牛久哲男
    • Organizer
      第15回日本消化管学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] 胎児型形質胃癌2019

    • Author(s)
      牛久哲男
    • Organizer
      第108回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] 胃癌におけるSWI/SNF複合体異常は腫瘍内不均一性が高くEBV・MSI陽性群で高頻度に認められる.2018

    • Author(s)
      岩崎晶子,牛久哲男,山澤翔,阿部浩幸,牛久綾,深山正久
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] Moving towards gastric cancer subtyping for precision medicine: molecular classification and beyond2018

    • Author(s)
      Tetsuo Ushiku
    • Organizer
      日本胃癌学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Presentation] 免疫組織学的に診断されたAFP産生胃癌の長期予後の検討.2018

    • Author(s)
      前澤幸男,利野靖,鈴木昭宏,青山徹,山田貴允,佐藤勉,大島貴,湯川寛夫,吉川貴己,牛久哲男,深山正久,石川俊平,油谷浩幸
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] 病理からみた胃腫瘍における個別化医療の現状と課題2018

    • Author(s)
      牛久哲男
    • Organizer
      第16回上部消化管外科懇話会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06983
  • [Presentation] ゲノム医療時代の胃癌病理学研究 基礎研究成果を生かし個別化医療の実現を目指す2017

    • Author(s)
      牛久 哲男
    • Organizer
      日本病理学会秋季特別総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Presentation] Gastric Cancer with Primitive Enterocyte Phenotype: An Aggressive Subgroup of Intestinal-Type Adenocarcinoma2017

    • Author(s)
      Tetsuo Ushiku; Sho Yamazawa; Aya Shinozaki-Ushiku; Masashi Fukayama
    • Organizer
      10th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Presentation] Carcinoma with primitive phenotype: an aggressive subgroup of intestinal-type gastric cancer2017

    • Author(s)
      Ushiku T, Yamazawa S, Iwasaki A, Shinozaki-Ushiku A, Seto Y, Fukayama M
    • Organizer
      日本胃癌学会総会
    • Place of Presentation
      広島
    • Year and Date
      2017-03-08
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Presentation] 特異な変異シグネチャーを有するびまん型胃癌の1 例2016

    • Author(s)
      牛久哲男、石川俊平、垣内美和子、油谷浩幸、深山正久
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Presentation] 胃癌におけるClaudin6の発現とその臨床病理学的意義についての検討2016

    • Author(s)
      山澤翔、牛久綾、牛久哲男、 深山 正久
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Presentation] びまん型胃癌におけるRHOA変異とCLDN18-ARHGAP転座の意義2016

    • Author(s)
      田中淳、牛久哲男、国田朱子、石川俊平、深山正久
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Presentation] 特異な変異シグネチャーを有するびまん型胃癌の1例2016

    • Author(s)
      牛久 哲男, 石川 俊平, 垣内 美和子, 油谷 浩幸, 深山 正久
    • Organizer
      日本病理学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K08340
  • [Presentation] Very Well Differentiated Gastric Cancer of Intestinal Metaplasia-Type: A Systemic Analysis2013

    • Author(s)
      Tetsuo Ushiku
    • Organizer
      The United States & Canadian Academy of Pathology’s 102nd Annual Meeting
    • Place of Presentation
      Boltimore, USA
    • Data Source
      KAKENHI-PROJECT-23790390
  • [Presentation] Focally enhanced gastritis in pediatric inflammatory bowel disease: patterns,associations and significance2013

    • Author(s)
      Ushiku T.
    • Organizer
      The United States & Canadian Academy of Pathology's 102 Annual Meeting.
    • Place of Presentation
      Baltimore, USA.
    • Year and Date
      2013-03-04
    • Data Source
      KAKENHI-PROJECT-23790390
  • [Presentation] Very well differentiated gastric cancer of intestinal metaplasia-type: a systemic analysis2013

    • Author(s)
      Ushiku T.
    • Organizer
      The United States & Canadian Academy of Pathology's 102nd Annual Meeting.
    • Place of Presentation
      Baltimore, USA.
    • Year and Date
      2013-03-05
    • Data Source
      KAKENHI-PROJECT-23790390
  • [Presentation] Glypican3を発現する胃癌の臨床病理学的特徴2009

    • Author(s)
      牛久哲男
    • Organizer
      第5回日本消化管学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-12
    • Data Source
      KAKENHI-PROJECT-19790251
  • [Presentation] Glypican 3を発現する胃癌の臨床病理学的特徴2009

    • Author(s)
      牛久哲男
    • Organizer
      第5回日本消化管学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-12
    • Data Source
      KAKENHI-PROJECT-19790251
  • [Presentation] Epstein-Barrウイルス関連早期胃癌の特徴と内視鏡治療適応の検討2009

    • Author(s)
      牛久哲男, 他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都国立京都国際会館
    • Year and Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Presentation] Epstein-Barrウイルス関連早期胃癌の特徴と内視鏡治療適応の検討2009

    • Author(s)
      牛久哲男
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Year and Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-19790251
  • [Presentation] Epstein-Barr ウイルス関連早期胃癌の特徴と内視鏡治療適応の検討2009

    • Author(s)
      牛久哲男
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Year and Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-19790251
  • [Presentation] 破骨細胞型巨細胞の出現を伴った胃癌の4例.2008

    • Author(s)
      牛久哲男ら
    • Organizer
      第97回日本病理学会総会
    • Place of Presentation
      金沢 もてなしドーム地下広場
    • Year and Date
      2008-05-15
    • Data Source
      KAKENHI-PROJECT-20249022
  • [Presentation] 胃癌におけるGlypican 3発現の意義およびAFP産生胃癌との関連2008

    • Author(s)
      牛久哲男
    • Organizer
      第80回日本胃癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-02-12
    • Data Source
      KAKENHI-PROJECT-19790251
  • [Presentation] 胃癌におけるGlypican3発現の意義およびAFP産生胃癌との関連2008

    • Author(s)
      牛久 哲男
    • Organizer
      第80回日本胃癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-02-28
    • Data Source
      KAKENHI-PROJECT-19790251
  • []

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  • 1.  FUKAYAMA Masashi (70281293)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 2.  UOZAKI Hiroshi (10296246)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 3.  SAKATANI Takashi (50431903)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 4.  HINO Rumi (60451770)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  MORIKAWA Teppei (80451772)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  KIKUCHI Yoshinao (90512260)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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  • 21.  鈴木 基文 (50401063)
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  • 28.  鎮西 清行 (60357506)
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  • 29.  Heredia Saul (00996788)
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  • 30.  MarquesMarinho Murilo (70837468)
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  • 38.  長谷川 潔 (20292906)
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  • 42.  OHTA Yasunori
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  • 45.  USHIKU Aya
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  • 46.  ABE Hiroyuki
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  • 47.  KANEDA Atsushi
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  • 48.  油谷 浩幸
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  • 49.  野村 幸世
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