Kitamatsu Mizuki 北松瑞生

… Alternative Names

KITAMATSU Mizuki 北松瑞生

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Researcher Number	60379716
Other IDs
Affiliation (Current)	2025: 近畿大学, 理工学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 近畿大学, 理工学部, 准教授 2018: 近畿大学, 理工学部, 准教授 2012 – 2017: 近畿大学, 理工学部, 講師 2010: 岡山大学, 自然科学研究科, 助教 2007 – 2010: Okayama University, 大学院・自然科学研究科, 助教 2006: 岡山大学, 大学院自然科学研究科, 助手 2005: 岡山大学, 工学部, 技術職員
Review Section/Research Field	Principal Investigator Chemistry related to living body / Bio-related chemistry / Basic Section 37010:Bio-related chemistry / Complex Systems Disease Theory Except Principal Investigator Neurosurgery / Radiation science / Periodontology / Periodontal dentistry / Chemical biology / Living organism molecular science / Science and Engineering
Keywords	Principal Investigator ペプチド核酸 / ペプチド / 細胞内運搬ペプチド / 細胞 / 細胞膜透過ペプチド / オートファジー / 蛍光 / UV融解曲線 / マイクロRNA / RNA検出 … More / 蛍光色素 / RNA / 癌 / ナノバイオ / アポトーシス / ドラッグデリバリーシステム / タンパク質 / Beclin-1 / Nanog / p53 / Nanogタンパク質 / p53タンパク質 / ロイシンジッパー / DDS / アルツハイマー / 蛍光アミノ酸 / アミノ酸 / 蛍光スペクトル / アミロイドβ / ペプチドライブラリー / アミロイド / ペプチド固相合成 / 細胞内導入 / 生体機能材料 / 生物有機化学 / 生体機能関連化学 / 細胞導入 / CHO細胞 / DNA / オキシペプチド核酸 … More Except Principal Investigator ペプチド核酸 / 細胞膜通過ペプチド / 悪性脳腫瘍 / ホウ素中性子捕捉療法（BNCT） / 粒子線治療 / ホウ素薬剤 / ＢＮＣＴ / アンチセンス / 歯周病原細菌 / スクリーニング / ペプチド / 2次元蛍光スペクトル / がん細胞 / ペプチドライブラリー / 蛍光性アミノ酸 / 細胞内導入 / 膠芽腫 / 創薬 / 陽電子放射断層撮影（ PET） / ホウ素製剤 / 陽電子放射断層撮影（PET) / BNCT / 癌 / 創薬研究 / ホウ素薬剤開発 / 放射線治療 / ＤＤＳ / がん治療 / 自己会合ペプチド / がん幹細胞 / 脳腫瘍 / ホウ素中性子捕捉療法 / ペプチドシグナル / 薬剤送達法 / 口腔細菌叢 / HSP60 / Porphyromonas gingivalis / 口腔内細菌叢 / 細菌叢 / アンチセンス医療 / キャリアーペプチド / 歯周病 / in vivo imaging / 蛍光 / ペプチドスクリーニング / 細胞識別 / 蛍光標識 / ステルス標識 / インビトロスクリーニング / RNA精製 / アレイ / noncoding RNA / miRNA / PNA / 人工核酸 Less

Intracellular delivery of functional peptides and maintain of the activity by "peptide nucleic acid zipper" methodPrincipal Investigator
- Principal Investigator
  
  KITAMATSU Mizuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Kindai University
Effective functional improvement of proteins and peptides delivered into cell by peptide zipper methodPrincipal Investigator
- Principal Investigator
  
  KITAMATSU Mizuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Kindai University
Live imaging of microRNA by intracellular-invasion peptide nucleic acid beaconPrincipal Investigator
- Principal Investigator
  
  KITAMATSU Mizuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  Kindai University
Growth inhibition of selected bacterial species by peptide nucleic acids for control of oral microflora
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Osaka Dental University
Development of new boron drugs and molecular imaging targeting for cancer stem cell
- Principal Investigator
  
  Matsui Hideki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Okayama University
New BNCT against brain tumor stem cell with BSH-peptide
- Principal Investigator
  
  Michiue Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Okayama University
Development of intracellular delivery method of proteins by hetero-dimerized leucine zippersPrincipal Investigator
- Principal Investigator
  
  KITAMATSU Mizuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Kinki University
Application of antisense PNA as antibiotics against periodontal pathogens
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka Dental University
  Okayama University
A search for peptides binding to assembly of amyloid-beta by novel fluorescence-screeningPrincipal Investigator
- Principal Investigator
  
  KITAMATSU Mizuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Okayama University
Construction of Drug-Discovering System by using Multiple Fluorescent Labels on Peptide Library
- Principal Investigator
  
  SISIDO Masahiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Okayama University
Screening of specific peptide for tumor cell by chemical biology method.
- Principal Investigator
  
  FUTAMI Midori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Okayama University
人工核酸によるRNAの検出と精製
- Principal Investigator
  
  大槻高史
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Okayama University
The development of peptide nucleic acids optimized cellular uptake and expression of their functions in cellsPrincipal Investigator
- Principal Investigator
  
  KITAMATSU Mizuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Okayama University
細胞に導入できる新規ペプチド核酸の開発と応用Principal Investigator
- Principal Investigator
  
  北松瑞生
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Okayama University

[Book] 新規モダリティ医薬品のための新しいDDS技術と製剤化第7章52023
- Author(s)
  北松瑞生、石井康稀、博多義之、宮澤正顯、道上宏之、大槻高史
- Total Pages
  580
- Publisher
  技術情報協会
- ISBN
  9784861049361
- Data Source
  KAKENHI-PROJECT-20K05714
[Journal Article] Adjusting Heterodimeric Coiled-coils (K/E zipper) to Connect Autophagy-inducing Peptide with Cell-penetrating Peptide2023
- Author(s)
  Yoshiyuki Hakata, Kazuma Yamashita, Sonoko Hashimoto, Takashi Ohtsuki, Masaaki Miyazawa, Mizuki Kitamatsu
- Journal Title
  
  Pharmaceutics
  
  Volume: 15 Issue: 4 Pages: 1048-1059
- DOI
  10.3390/pharmaceutics15041048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05714, KAKENHI-PROJECT-23K24120
[Journal Article] Fluorescence Ratiometric DNA Detection by Peptide Nucleic Acid-Pyrene Binary Probes2022
- Author(s)
  Koki Ishii, Sakura Tsuchitani, Miyu Toyama, Hajime Shigeto, Shohei Yamamura, Takashi Ohtsuki, Yoshitane Imai, Mizuki Kitamatsu
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 71 Pages: 128838-128841
- DOI
  10.1016/j.bmcl.2022.128838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05714, KAKENHI-PROJECT-23K25237
[Journal Article] Complementary Leucine Zippering System for Effective Intracellular Delivery of Proteins by Cell-Penetrating Peptides2021
- Author(s)
  Mizuki Kitamatsu, Hiroki Yuasa, Takashi Ohtsuki, Hiroyuki Michiue
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 33 Pages: 116036-116041
- DOI
  10.1016/j.bmc.2021.116036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05714, KAKENHI-PROJECT-18H02090, KAKENHI-PROJECT-18K07324, KAKENHI-PROJECT-18K08944
[Journal Article] A leucine zipper-based peptide hybrid delivers functional Nanog protein inside the cell nucleus.2019
- Author(s)
  Yoshiyuki Hakata, Hiroyuki Michiue, Takashi Ohtsuki, Masaaki Miyazawa and Mizuki Kitamatsu
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Issue: 7 Pages: 878-881
- DOI
  10.1016/j.bmcl.2019.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05199, KAKENHI-PROJECT-16K05856, KAKENHI-PROJECT-16K08821, KAKENHI-PROJECT-18K07324, KAKENHI-PROJECT-18K08944, KAKENHI-PROJECT-19H03481
[Journal Article] Tumor-specific delivery of BSH-3R for boron neutron capture therapy and positron emission tomography imaging in a mouse brain tumor model.2015
- Author(s)
  Iguchi Y, Michiue H, Kitamatsu M, Hayashi Y, Takenaka F, Nishiki T, Matsui H.
- Journal Title
  
  Biomaterials.
  
  Volume: 56 Pages: 10-7
- DOI
  10.1016/j.biomaterials.2015.03.061
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04906
[Journal Article] Tumor-specific delivery of BSH-3R for boron neutron capture therapy and positron emission tomography imaging in a mouse brain tumor model.2015
- Author(s)
  Iguchi Y, Michiue H, Kitamatsu M, Hayashi Y, Takenaka F, Nishiki T, Matsui H.
- Journal Title
  
  Biomaterials.
  
  Volume: 56 Pages: 10-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10333
[Journal Article] Novel leucine zipper motif-based hybrid peptide delivers functional peptide cargo inside cells.2015
- Author(s)
  Hakata, Y., S. Tsuchiya, H. Michiue, T. Ohtsuki, H. Matsui, M. Miyazawa, and M. Kitamatsu
- Journal Title
  
  Chem. Comm.
  
  Volume: 51 Issue: 2 Pages: 413-416
- DOI
  10.1039/c4cc07459a
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390116, KAKENHI-PROJECT-24390293, KAKENHI-PROJECT-24791502, KAKENHI-PROJECT-25282232, KAKENHI-PROJECT-25410181, KAKENHI-PROJECT-25460573, KAKENHI-PROJECT-25560224, KAKENHI-PUBLICLY-26107711
[Journal Article] Antisense effects of pyrrolidine-based oxy-peptide nucleic acids in Escherichia coli2011
- Author(s)
  M.Kitamatsu, S.Kurami, T.Ohtsuki, M.Sisido
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21 Pages: 225-227
- NAID
  120003353368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] A novel method for screening peptides that bind to proteins by using multiple fluorescent amino acids as fluorescent tags.2010
- Author(s)
  Kitamatsu M, Futami M, Sisido M
- Journal Title
  
  Chem Commun (Camb) 46
  
  Pages: 761-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611011
[Journal Article] Quantitative screening of EGF receptor-binding peptides by using a peptide library with multiple fluorescent amino acids as fluorescent tags.2010
- Author(s)
  Kitamatsu M, Yamamoto T, Futami M, Sisido M
- Journal Title
  
  Bioorg Med Chem Lett. 20
  
  Pages: 5976-5978
- NAID
  120003386547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611011
[Journal Article] Quantitative Screening of EGF Receptor-Binding Peptide by Using a Peptide Library with Multiple Fluorescent Amino Acids as Fluorescent Tags2010
- Author(s)
  M.Kitamatsu, T.Yamamoto, M.Futami, M.Sisido
- Journal Title
  
  Bioorg.Med.Chem.Lett
  
  Volume: 20 Pages: 5976-5978
- NAID
  120003386547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] Quantitative screening of EGF receptor-binding peptides by using a peptide library with multiple fluorescent amino acids as fluorescent tags.2010
- Author(s)
  Kitamatsu M, Yamamoto T, Futami M, Sisido M.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 20 Pages: 5976-5978
- NAID
  120003386547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611011
[Journal Article] Prevention of adsorption of fluorescent amino acides to gels by using a peptide containinig dendritic amino acids.2010
- Author(s)
  Mizuki Kitamatsu, Kazumasa Akagi, Masahiko Sisido.
- Journal Title
  
  Chemistry Letters 39
  
  Pages: 1240-1241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750172
[Journal Article] Prevention of Absorption of Fluorescent Amino Acids to Gels by Using a Peptide Containing Dendritic Amino Acids2010
- Author(s)
  M.Kitamatsu, K.Akagi, M.Sisido
- Journal Title
  
  Chem.Lett. 39
  
  Pages: 1240-1241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] A novel method for screening peptides that bind to proteins by using multiple fluorescent amino acids as fluorescent tags.2010
- Author(s)
  Kitamatsu M, Futami M, Sisido M.
- Journal Title
  
  Chem Commun (Camb)
  
  Volume: 46 Pages: 761-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20611011
[Journal Article] A Novel Method for Screeninig Peptides that Bind to Proteins by Using Multiple Fluorescent Amino Acides as Fluorescent Tags2010
- Author(s)
  M.Kitamatsu, M.Futami, M.Sisido
- Journal Title
  
  Chem.Commun
  
  Volume: 46 Pages: 761-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] Synthesis of pyrrolidine-based oxay-peptide nucleic acids carrying four types of nucleobases and their transport into cytoplasm2010
- Author(s)
  M.Kitamatsu, A.Takahashi, T.Ohtsuki M.Sisido
- Journal Title
  
  Tetrahedron
  
  Volume: 66 Pages: 9659-9666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] Prevention of a dsorption of fluorescent amino acides to gels by using a peptide containinig dendritic amino acids2010
- Author(s)
  Mizuki Kitamatsu, Kazumasa Akagi, Masahiko Sisido
- Journal Title
  
  Chemistry Letters
  
  Volume: 39 Pages: 1240-1241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750172
[Journal Article] A Novel Method for Screeninig Peptides that Bind to Proteins by Using Multiple Fluorescent Amino Acides as Fluorescent Tags2010
- Author(s)
  M.Kitamatsu, M.Futami, M.Sisido
- Journal Title
  
  Chem.Comm. 46
  
  Pages: 761-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] Prevention of adsorption of fluorescent amino acides to gels by using a peptide containinig dendritic amino acids.2010
- Author(s)
  Takamitsu Morikawa, Mizuki Kitamatsu, Masahiko Sisido.
- Journal Title
  
  Peptide Science 2009
  
  Pages: 369-370
- Data Source
  KAKENHI-PROJECT-21750172
[Journal Article] A search for peptides binding to assembly of amyloid-beta by novel fluorescence-screening2010
- Author(s)
  Takamitsu Morikawa, Mizuki Kitamatsu, Masahiko Sisido
- Journal Title
  
  Peptide Science 2009
  
  Pages: 369-370
- Data Source
  KAKENHI-PROJECT-21750172
[Journal Article] Prevention of Absorption of Fluorescent Amino Acids to Gels by Using a Peptide Containing Dendritic Amion Acids2010
- Author(s)
  M.Kitamatsu, K.Akagi, M.Sisido
- Journal Title
  
  Chem Lett
  
  Volume: 39 Pages: 1240-1241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] PNA arrays for miRNA detection2009
- Author(s)
  T.Endoh, M.Kitamatsu, M.Sisido, T.Ohtsuki
- Journal Title
  
  Chem. Lett 38
  
  Pages: 438-439
- NAID
  10025121754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] Carrier PNA for shRNA delivery into cells2009
- Author(s)
  M.Kitamatsu, T.Kubo, R.Matsuzaki, T.Endoh, T.Ohtsuki, M.Sisido
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 19
  
  Pages: 3410-3412
- NAID
  120003386546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] PNA arrays for miRNA detection2009
- Author(s)
  Endoh, T., Kitamatsu, M., Sisido M. and Ohtsuki, T.
- Journal Title
  
  Chemistry Letters 38
  
  Pages: 438-439
- NAID
  10025121754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021034
[Journal Article] Isolation of small RNAs using biotinylated PNAs.2008
- Author(s)
  T. Ohtsuki. T. Fujimoto, M. Kamimukai, C. Kumano, M. Kitamatsu, M. Sisido
- Journal Title
  
  Journal of Biochemistry 144
  
  Pages: 415-418
- NAID
  10024912545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241054
[Journal Article] Isolation of small RNAs using biotinylated PNAs2008
- Author(s)
  Ohtsuki, T., Fujimoto, T., Kamimukai, M., Kumano, C., Kitamatsu, M., Sisido, M.
- Journal Title
  
  Journal of Biochemistry 144
  
  Pages: 415-418
- NAID
  10024912545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021034
[Journal Article] Introduction of Pyrrolidine-Based Oxy-PNA into Cytoplasm of CHO Cells2006
- Author(s)
  Akiko TAKAHASHI, Rino MATSUZAKI, Mizuki KITAMATSU, Masahiko SISIDO
- Journal Title
  
  Peptide Science 2006
  
  Pages: 233-233
- NAID
  10020529746
- Data Source
  KAKENHI-PROJECT-17750160
[Journal Article] Antisense Effects of Pyrrolidine-Based Oxy-PNAs Conjugated with a Membrane-Permeable Peptide in Escherichia coli2006
- Author(s)
  Syunsuke KURMI, Mizuki KITAMATSU, Takashi OHTSUKI, Masahiko SISIDO
- Journal Title
  
  Peptide Science 2006
  
  Pages: 234-234
- NAID
  10020529749
- Data Source
  KAKENHI-PROJECT-17750160
[Journal Article] Synthesis of a Novel Pyrrolidine-Based Peptide Nucleic Acid that Contains Tertiary Amines in the Main Chain and its Internalization into Cells2005
- Author(s)
  Mizuki KITAMATSU
- Journal Title
  
  Chemistry Letters 35
  
  Pages: 300-301
- NAID
  10017273480
- Data Source
  KAKENHI-PROJECT-17750160
[Journal Article] Carrier PNA for shRNA delivery into cells
- Author(s)
  Mizuki Kitamatsu, Takanori Kubo, Rino Matsuzaki, Tamaki Endoh, Takashi Ohtsuki, Masahiko Sisido
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 19
  
  Pages: 3410-3413
- NAID
  120003386546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19750143
[Patent] 新規分岐状アミノ酸、新規分岐状アミノ酸と蛍光性アミノ酸の複合体2010
- Inventor(s)
  北松瑞生
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2010-216789
- Filing Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-21750172
[Patent] 新規アミロイドβ凝集体結合性ペプチドおよび新規アミロイドβ凝集体結合性ペプチドを用いたアミロイド病の検査方法2009
- Inventor(s)
  北松瑞生
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2009-206771
- Filing Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-21750172
[Patent] 新規アミロイドβ凝集体結合性ペプチドおよび新規アミロイドβ凝集体結合性ペプチドを用いたアミロイド病の検査方法2009
- Inventor(s)
  北松瑞生
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2009-206771
- Acquisition Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-21750172
[Patent] 修飾型PNA/RNA複合体2008
- Inventor(s)
  北松瑞生・他4名
- Industrial Property Rights Holder
  岡山大学・産業技術総合研究所
- Industrial Property Number
  2008-028986
- Filing Date
  2008-02-08
- Data Source
  KAKENHI-PROJECT-19750143
[Patent] 修飾型PNA/RNA複合体2007
- Inventor(s)
  北松瑞生、大槻高史、宍戸昌彦、久保貴紀、大庭英樹
- Industrial Property Rights Holder
  岡山大学・産業技術総合研究所
- Industrial Property Number
  2007-037041
- Filing Date
  2007-02-16
- Data Source
  KAKENHI-PROJECT-19021034
[Presentation] ナフチル基修飾ロイシンジッパーによる機能性ペプチドハイブリッド形成およびその細胞内運搬2022
- Author(s)
  中村高広, 博多義之, 宮澤正顯, 北松瑞生
- Organizer
  第37回関西地区ペプチドセミナー
- Data Source
  KAKENHI-PROJECT-20K05714
[Presentation] 非天然アミノ酸を含むヘテロ二量体化ロイシンジッパーを用いた機能性ペプチドの細胞内運搬2022
- Author(s)
  中村高広, 井上健, 藤本翔夢, 北松瑞生, 宮澤正顯, 博多義之
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-20K05714
[Presentation] 非天然アミノ酸を含むヘテロ二量体化ロイシンジッパーを用いた機能性ペプチドの細胞内運搬2021
- Author(s)
  中村高広, 井上健, 藤本翔夢, 北松瑞生, 宮澤正顯, 博多義之
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-20K05714
[Presentation] ペプチドジッパーによるオートファジー誘導ペプチドと細胞内運搬ペプチドの合成および評価2021
- Author(s)
  石井康稀, 北松瑞生, 宮澤正顯, 博多義之
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-20K05714
[Presentation] ペプチド核酸ファスナーによる機能性ペプチドと細胞膜透過ペプチドの連結および細胞内活性評価2021
- Author(s)
  石井康稀, 北松瑞生, 星野愛可里, 山口祐史, 宮澤正顯, 博多義之
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-20K05714
[Presentation] ペプチドファスナーによる機能性ペプチドと細胞膜透過ペプチドの連結および細胞内活性評価2021
- Author(s)
  井上健, 北松瑞生, 山下和真, 宮澤正顯, 博多義之
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-20K05714
[Presentation] フルオレセイン基とダブシル基を含むペプチド核酸をプローブとして用いたRNAの蛍光検出2019
- Author(s)
  岸高稚, 北松瑞生, 大槻高史
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-16KT0195
[Presentation] アクリドニル基とベンゾアクリドニル基を含むペプチド核酸をプローブとして用いたRNAの蛍光検出2019
- Author(s)
  松原慶季, 北松瑞生, 大槻高史
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-16KT0195
[Presentation] マイクロRNA検出のための蛍光基/消光基型ペプチド核酸ビーコンの構造最適化2018
- Author(s)
  岸高稚, 北松瑞生, 大槻高史
- Organizer
  第35回関西地区ペプチドセミナー
- Data Source
  KAKENHI-PROJECT-16KT0195
[Presentation] マイクロRNA検出のためのFRET型ペプチド核酸ビーコンの構造最適化2018
- Author(s)
  松原慶季, 北松瑞生, 大槻高史
- Organizer
  第35回関西地区ペプチドセミナー
- Data Source
  KAKENHI-PROJECT-16KT0195
[Presentation] The next generation Boron agents with BSH fused Cell Penetrating Peptide toward clinical application2017
- Author(s)
  Hiroyuki Michiue, Mizuki Kitamatsu, Natsuko Kondo, Yoshinori Sakurai, Hideki Matsui
- Organizer
  9th Young Researchers' BNCT Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10333
[Presentation] 細胞内侵入型ペプチド核酸ビーコンの開発2017
- Author(s)
  松原慶季, 北松瑞生, 大槻高史
- Organizer
  第34回関西地区ペプチドセミナー
- Data Source
  KAKENHI-PROJECT-16KT0195
[Presentation] 光増感剤－機能性ペプチド－細胞内運搬ペプチドによるアポトーシスの光誘起誘導法の開発2016
- Author(s)
  隅田健斗、北松瑞生、大槻高史
- Organizer
  第33回関西地区ペプチドセミナー
- Place of Presentation
  大阪府東大阪市近畿大学
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16KT0195
[Presentation] Cellular Delivery and Apoptosis Induction by a Conjugate of Apoptosis-Inducing Peptide and Cell-Penetrating Peptide Modified with a Photosensitizer2016
- Author(s)
  Mizuki Kitamatsu, Hayato Fujiwara, Kazunori Watanabe, Takashi Ohtsuki
- Organizer
  9th Asian Photochemistry Conferences
- Place of Presentation
  Singapore
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0195
[Presentation] 光増感剤－機能性ペプチド－細胞内運搬ペプチドによるアポトーシスの光誘起誘導法の開発2016
- Author(s)
  隅田健斗、北松瑞生、大槻高史
- Organizer
  第33回関西地区ペプチドセミナー
- Place of Presentation
  大阪府東大阪市近畿大学
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16K05856
[Presentation] Cellular Delivery and Apoptosis Induction by a Conjugate of Apoptosis-Inducing Peptide and Cell-Penetrating Peptide Modified with a Photosensitizer2016
- Author(s)
  Mizuki Kitamatsu, Hayato Fujiwara, Kazunori Watanebe, Takashi Ohtsuki
- Organizer
  9th Asian Photochemistry Conferences
- Place of Presentation
  Singapore
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05856
[Presentation] The Development of BSH Fused Cell-penetrating Peptide towards Clinical Application2015
- Author(s)
  Hiroyuki Michiue1, Yoshiya Iguchi1, Mizuki Kitamatsu2, Hiroaki Matsushita1, Tei-ichi Nishiki1, Hideki Matsui1
- Organizer
  International Congress of Radiation Research 2015
- Place of Presentation
  京都国際会議場
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10333
[Presentation] BSH-peptide delivery system and drug pharmacokinetics by positron emission tomography (PET) imaging2015
- Author(s)
  Hiroyuki Michiue1 , Yoshiya Iguchi1, Mizuki Kitamatsu2, Hiroaki Matsushita1, Tei-ichi Nishiki1, Hideki Matsuil1
- Organizer
  The8th Young Researchers BNCT Meeting
- Place of Presentation
  Pavia, Italy
- Year and Date
  2015-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10333
[Presentation] Peptide nucleic acid that conjugates with a cell-penetrating peptide via a disulfide bond for detecting a specific small RNA inside cells2015
- Author(s)
  Mizuki Kitamatsu and Takashi Ohtsuki
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410181
[Presentation] Development of the new boron agent, BSH-peptide, towards clinical application2015
- Author(s)
  Hiroyuki Michiue, Yoshiya Iguchi, Mizuki Kitamatsu, Hiroaki Matsushita, Tei-ichi Nishiki, Hideki Matsui
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  京都国際会議場
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04906
[Presentation] BSH-peptide delivery system and drug pharmacokinetics by positron emission tomography (PET) imaging2015
- Author(s)
  Hiroyuki Michiue, Yoshiya Iguchi, Mizuki Kitamatsu, Hiroaki Matsushita, Tei-ichi Nishiki, Hideki Matsuil
- Organizer
  8th Young Boron Neutron Capture Therapy
- Place of Presentation
  Pavia in Italy
- Year and Date
  2015-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04906
[Presentation] ペプチド‐ペプチドハイブリッド法によるオートファジー誘導ペプチドの効果的輸送2014
- Author(s)
  鷺森直人、博多義之、北松瑞生
- Organizer
  第46回若手ペプチド夏の勉強会
- Place of Presentation
  京都府・宮津市・京都府立青少年海洋センター
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PROJECT-25410181
[Presentation] ペプチドハイブリッド法によるオートファジー誘導ペプチドの細胞内輸送2014
- Author(s)
  鷺森直人、北松瑞生、博多義之、宮澤正顯
- Organizer
  第29回関西地区ペプチドセミナー
- Place of Presentation
  大阪府・吹田市・関西大学（千里山キャンパス）
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-25410181
[Presentation] Delivery of peptides into cells by peptide-peptide hybrid method2014
- Author(s)
  M. Kitamatsu, T. Ohtsuki
- Organizer
  15th Tetrahedron Symposium
- Place of Presentation
  London, UK
- Year and Date
  2014-06-26
- Data Source
  KAKENHI-PROJECT-25410181
[Presentation] A Method for Screening Peptides Bound to EGFR by Using Multiple Fluorescent Amino Acids as Fluorescent Tags2010
- Author(s)
  M.Kitamatsu, T.Yamamoto, M.Sisido
- Organizer
  The 31st European Peptide Symposium
- Place of Presentation
  Copenhagen, Denmark.
- Year and Date
  2010-09-05
- Data Source
  KAKENHI-PROJECT-20241054
[Presentation] A Method for Screening Peptides Bound to EGFR by Using Multiple Fluorescent Amino Acids as Fluorescent Tags2010
- Author(s)
  M.Kitamatsu, T.Yamamoto, M.Sisido
- Organizer
  The 31st European Peptide Symposium
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2010-09-05
- Data Source
  KAKENHI-PROJECT-20241054
[Presentation] A Search for Peptides Binding to Assembly of Amyloid-Beta by Novel Fluorescence-Screening2009
- Author(s)
  北松瑞生
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  福岡・北九州国際会議場
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-21750172
[Presentation] A Search for Peptides Binding to Assembly of Amyloid-Beta by Novel Fluorescence-Screening2009
- Author(s)
  T.MORIKAWA, M.KITAMATSU, M.SISIDO
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-20241054
[Presentation] A Search for Peptides Binding to EGFR by Novel Fluorescence-Screening2009
- Author(s)
  T.YAMAMOTO, M.KITAMATSU, M.SISIDO
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-20241054
[Presentation] Multi-component Fluorescence labeling method for Efficient Positional Screening of Peptide Library2008
- Author(s)
  M. Kitamatsu, H. Kuroiwa. D. Sakata. S. Neki. S. Yagi, T.
- Organizer
  30th European Peptide Symposium
- Place of Presentation
  Helsinki
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-20241054
[Presentation] 蛍光基を側鎖にもつ非天然アミノ酸群の合成2008
- Author(s)
  北松瑞生
- Organizer
  第57回高分子学会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2008-05-28
- Data Source
  KAKENHI-PROJECT-20611011
[Presentation] Multi-component Fluorescence labeling method for Efficient Positional Screening of Peptide Library2008
- Author(s)
  M.KITAMATSU
- Organizer
  30th European Peptide Symposium.
- Place of Presentation
  ヘルシンキ
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-20611011
[Presentation] Multi-component Fluorescence labeling method for Efficient Positional Screening of Peptide Library2008
- Author(s)
  M. KITAMATSU
- Organizer
  30th European Peptide Symposium
- Place of Presentation
  ヘルシンキ
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-20611011
[Presentation] 「水溶性の高いペプチド核酸の合成」2007
- Author(s)
  北松瑞生、定石圭司、宍戸昌彦
- Organizer
  2007日本化学会西日本大会
- Place of Presentation
  岡山
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19750143
[Presentation] 「ペプチド核酸-細胞内導入ペプチドコンジュゲートを用いたRNA の細胞内送達」2007
- Author(s)
  久保貴紀、北松瑞生、遠藤玉樹、山中智史、大庭英樹、大槻高史、宍戸昌彦
- Organizer
  2007日本化学会西日本大会
- Place of Presentation
  岡山
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19750143
[Presentation] 「ペプチド核酸-膜透過ペプチドオリゴマーをキャリアーとして用いたsiRNA の細胞内輸送」2007
- Author(s)
  北松瑞生、久保貴紀、遠藤玉樹、大庭英樹、大槻高史、宍戸昌彦
- Organizer
  第17回バイオ・高分子シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-07-31
- Data Source
  KAKENHI-PROJECT-19750143
[Presentation] "Synthesis and Cell-internalization of a Cationic Peptide Nucleic Acid that Carries Pyrrolidine Rings"2007
- Author(s)
  T. Kashiwagi, M. Kitamatsu and M. Sisido
- Organizer
  20th American Peptide Symposium
- Place of Presentation
  アメリカ
- Data Source
  KAKENHI-PROJECT-19750143
[Presentation] ペプチド核酸-膜透過ペプチドオリゴマーをキャリアーとして用いたsiRNAの細胞内輸送2007
- Author(s)
  北松瑞生、久保貴紀、大庭英樹、遠藤玉樹、大槻高史、宍戸昌彦
- Organizer
  第17回バイオ・高分子シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-07-31
- Data Source
  KAKENHI-PROJECT-19021034
[Presentation] 水溶性の高いペプチド核酸の合成2007
- Author(s)
  北松瑞生・定石圭司・宍戸昌彦
- Organizer
  2007日本化学会西日本大会
- Place of Presentation
  岡山(岡山大学)
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19750143
[Presentation] 「ペプチド核酸-膜透過ペプチドコンジュゲートによるsiRNAの細胞内輸送」2007
- Author(s)
  久保貴紀、北松瑞生、遠藤玉樹、大槻高史、大庭秀樹、宍戸昌彦
- Organizer
  日本ケミカルバイオロジー研究会第2回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19750143
[Presentation] RNA isolation using biotinylated PNAs2007
- Author(s)
  T. Ohtsuki, T. Fujimoto. M. Kamimukai, M. Kitamatsu, M. Sisido
- Organizer
  The 2nd International Workshop on Approaches to Single Cell Analysis
- Place of Presentation
  Tokyo
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-19021034

1. MICHIUE Hiroyuki (20572499)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. SISIDO Masahiko (60026268)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
3. MAEDA Hiroshi (00274001)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TAKASHIBA Shogo (50226768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KOKEGUCHI Susumu (10144776)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 大槻高史 (80321735)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
7. FUTAMI Midori (10467748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. YAMASHIRO Keisuke (30581087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MINESHIBA Fumi (90346461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Matsui Hideki (30157234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. MIYATAKE Shin-ichi (90209916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MATSUSHITA Hiroaki (60732394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. ISOSHIMA Daichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HAKATA Yoshiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 宮澤正顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kitamatsu Mizuki 北松 瑞生

KITAMATSU Mizuki 北松 瑞生

Research Projects

Research Products

Co-Researchers

Intracellular delivery of functional peptides and maintain of the activity by "peptide nucleic acid zipper" methodPrincipal Investigator

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Effective functional improvement of proteins and peptides delivered into cell by peptide zipper methodPrincipal Investigator

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Live imaging of microRNA by intracellular-invasion peptide nucleic acid beaconPrincipal Investigator

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Growth inhibition of selected bacterial species by peptide nucleic acids for control of oral microflora

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Development of new boron drugs and molecular imaging targeting for cancer stem cell

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New BNCT against brain tumor stem cell with BSH-peptide

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Development of intracellular delivery method of proteins by hetero-dimerized leucine zippersPrincipal Investigator

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Application of antisense PNA as antibiotics against periodontal pathogens

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A search for peptides binding to assembly of amyloid-beta by novel fluorescence-screeningPrincipal Investigator

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Construction of Drug-Discovering System by using Multiple Fluorescent Labels on Peptide Library

Principal Investigator

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Screening of specific peptide for tumor cell by chemical biology method.

Principal Investigator

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人工核酸によるRNAの検出と精製

Principal Investigator

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Review Section

Research Institution

The development of peptide nucleic acids optimized cellular uptake and expression of their functions in cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Kitamatsu Mizuki 北松瑞生

KITAMATSU Mizuki 北松瑞生

[Book] 新規モダリティ医薬品のための新しいDDS技術と製剤化第7章52023