Saito Shin 齋藤心

Researcher Number	60382909
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 自治医科大学, 医学部, 准教授 2018 – 2020: 自治医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 質量分析 / 免疫逃避 / トロゴサイトーシス / 接着分子 / リンパ球 / がん転移 / トルゴサイトーシス / 上皮間葉移行 / 浸潤 / 平滑筋細胞 / スキルス胃癌 … More Except Principal Investigator … More 腹膜播種 / 胃癌 / 遺伝子治療 / エクソソーム / 大網乳斑 / microRNA / がん微小環境 / 発がん / 再発 / 上部消化管癌 / 大網 / 腹腔内マクロファージ / がん免疫微小環境 / 肝転移 / 大網乳班 / T細胞 / マクロファージ / 腹腔免疫 / 大腸乳斑 / コリン作動性シグナル / 迷走神経 Less

Development of novel therapy targeting microRNA for peritoneal dissemination and elucidation of its immunological mechanism
- Principal Investigator
  
  北山丈二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jichi Medical University
Role of trogositosis in tumor immune escapePrincipal Investigator
- Principal Investigator
  
  Saito Shin
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jichi Medical University
Oncological significance of vagotomy in upper gastrointestinal surgery
- Principal Investigator
  
  Hosoya Yoshinori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jichi Medical University
Role of smooth muscle cells in invasion and metastasis of scirrhous gastric cancerPrincipal Investigator
- Principal Investigator
  
  Saito Shin
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jichi Medical University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] miR－29b内包エクソソームの腹腔内補充は胃癌腹膜播種を抑制する2023
- Author(s)
  木村有希, 大澤英之, 勇希, 金子, 倉科憲太郎, 齋藤心, 山口博紀, 細谷好則, 宮戸秀世, 佐田尚宏,北山丈二.
- Journal Title
  
  癌と化学療法
  
  Volume: 50 Pages: 1435-1437
- Data Source
  KAKENHI-PROJECT-23K27676
[Journal Article] Intraperitoneal transfer of microRNA‐29b‐containing small extracellular vesicles can suppress peritoneal metastases of gastric cancer2023
- Author(s)
  Kimura Yuki、Ohzawa Hideyuki、Miyato Hideyo、Kaneko Yuki、Kuchimaru Takahiro、Takahashi Rei、Yamaguchi Hironori、Kurashina Kentaro、Saito Shin、Hosoya Yoshinori、Lefor Alan Kawarai、Sata Naohiro、Kitayama Joji
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 7 Pages: 2939-2950
- DOI
  10.1111/cas.15793
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07704, KAKENHI-PROJECT-21K08649, KAKENHI-PROJECT-23K27676
[Journal Article] Synopsis of a clinical practice guideline for pancreatic ductal adenocarcinoma with peritoneal dissemination in Japan; Japan Peritoneal Malignancy Study Group.2022
- Author(s)
  Satoi, S., N. Takahara, T. Fujii, H. Isayama, S. Yamada, Y. Tsuji, H. Miyato, H. Yamaguchi, T. Yamamoto, D. Hashimoto, S. Yamaki, Y. Nakai, K. Saito, H. Baba, T. Watanabe, S. Ishii, M. Hayashi, K. Kurimoto, H. Shimada,J. Kitayama
- Journal Title
  
  J Hepatobiliary Pancreat Sci 29(6):600-608.
  
  Volume: 29(6) Issue: 6 Pages: 600-608
- DOI
  10.1002/jhbp.1085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08649
[Journal Article] MiR-29b may suppresses peritoneal metastases through inhibition of the mesothelial?mesenchymal transition (MMT) of human peritoneal mesothelial cells2022
- Author(s)
  Kimura Yuki、Ohzawa Hideyuki、Miyato Hideyo、Kaneko Yuki、Saito Akira、Takahashi Kazuya、Tojo Mineyuki、Yamaguchi Hironori、Kurashina Kentaro、Saito Shin、Hosoya Yoshinori、Lefor Alan Kawarai、Sata Naohiro、Kitayama Joji
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 205-205
- DOI
  10.1038/s41598-021-04065-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08740, KAKENHI-PROJECT-20K07704, KAKENHI-PROJECT-20K08989
[Journal Article] Altered intraperitoneal immune microenvironment in patients with peritoneal metastases from gastric cancer2022
- Author(s)
  Takahashi Kazuya、Kurashina Kentaro、Yamaguchi Hironori、Kanamaru Rihito、Ohzawa Hideyuki、Miyato Hideyo、Saito Shin、Hosoya Yoshinori、Lefor Alan Kawarai、Sata Naohiro、Kitayama Joji
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 01-10
- DOI
  10.3389/fimmu.2022.969468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08740, KAKENHI-PROJECT-21K16432
[Journal Article] Effect of Systemic or Intraperitoneal Administration of Anti-PD-1 Antibody for Peritoneal Metastases from Gastric Cancer2022
- Author(s)
  KUMAGAI YUKO、FUTOH YURIE、MIYATO HIDEYO、OHZAWA HIDEYUKI、YAMAGUCHI HIRONORI、SAITO SHIN、KURASHINA KENTARO、HOSOYA YOSHINORI、LEFOR ALAN KAWARAI、SATA NAOHIRO、KITAYAMA JOJI
- Journal Title
  
  In Vivo
  
  Volume: 36 Issue: 3 Pages: 1126-1135
- DOI
  10.21873/invivo.12811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08740, KAKENHI-PROJECT-22K16543, KAKENHI-PROJECT-20K08989, KAKENHI-PROJECT-21K20958
[Journal Article] Intraperitoneal Administration of Paclitaxel Combined with S-1 Plus Oxaliplatin as Induction Therapy for Patients with Advanced Gastric Cancer with Peritoneal Metastases2020
- Author(s)
  S. Saito, H. Yamaguchi, H. Ohzawa, H. Miyato, R. Kanamaru, K. Kurashina, Y. Hosoya, A. K. Lefor, N. Sata,J. Kitayama.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: - Issue: 7 Pages: 1-8
- DOI
  10.1245/s10434-020-09388-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07704, KAKENHI-PROJECT-20K22960, KAKENHI-PROJECT-18K08691, KAKENHI-PROJECT-20K08989
[Journal Article] Synchronous gastric leiomyoma and intramuscular abdominal wall granular cell tumor with similar imaging features: A case report.2018
- Author(s)
  Saito S, Yan C, Fukuda H, Hosoya Y, Matsumoto S, Matsubara D, Kitayama J,Lefor AK, Sata N.
- Journal Title
  
  Int J Surg Case Rep
  
  Volume: 44 Pages: 207-211
- DOI
  10.1016/j.ijscr.2018.03.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-18K08691
[Presentation] Eosinophil might be related with the response of peritoneal metastases against intraperitoneal chemotherapy in patients with gastric caner.2023
- Author(s)
  Kazuya Takahashi, Misaski Masumiya, Yuki Kaneko, Kentaro Kurashina, Shin Saito, Hideyo Miyato, Yoshinori Hosoya, Naohiro Sata, Hideyuki Ohzawa, Hironori Yamaguchi, Joji Kitayama.
- Organizer
  The 13th PSOGI International Congres on Peritoneal Surface Malignancies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27676
[Presentation] Conversion gastrectomy after SOX+intraperitoneal paclitaxel for the patients with peritoneal dissemination from gastric cancer -Outcome analysis by ascites Volume-2023
- Author(s)
  Joji Kitayama, Hironori Yamaguchi, Hideyuki Ohzawa, Kazuya Takahashi, Rihito Kanamaru, Shin Saito, Yoshinori Hosoya,Naohiro Sata
- Organizer
  International Gastric Cancer Congress 2023
- Data Source
  KAKENHI-PROJECT-21K08649
[Presentation] Conversion gastrectomy after SOX+intraperitoneal paclitaxel for the patients with peritoneal dissemination from gastric cancer -Outcome analysis by ascites Volume-2023
- Author(s)
  Joji Kitayama, Hironori Yamaguchi, Hideyuki Ohzawa, Kazuya Takahashi, Rihito Kanamaru, Shin Saito, Yoshinori Hosoya,Naohiro Sata.
- Organizer
  International Gastric Cancer Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27676
[Presentation] Eosinophil might be related with the response of peritoneal metastases against intraperitoneal chemotherapy in patients with gastric caner.2023
- Author(s)
  Kazuya Takahashi, Misaski Masumiya, Yuki Kaneko, Kentaro Kurashina, Shin Saito, Hideyo Miyato, Yoshinori Hosoya, Naohiro Sata, Hideyuki Ohzawa, Hironori Yamaguchi, Joji Kitayama
- Organizer
  The 13th PSOGI International Congres on Peritoneal Surface Malignancies
- Data Source
  KAKENHI-PROJECT-21K08649
[Presentation] Conversion surgery after intraperitoneal paclitaxel combined with systemic oxaliplatin and oral S-1 (SOX) for patients with peritoneal metastasis from gastric cancer.2023
- Author(s)
  Rihito Kanamaru, Hironori Yamaguchi, Yuki Kimra, Kazuya Takahashi, Takehiro Kagaya, Toru Takagi, Shiro Matsumoto, Kentaro Kurashina, Shin Saito, Yoshinori Hosoya, Naohiro Sata,Joji Kitayama
- Organizer
  Advanced Caner Therapies 2023 (SSO)
- Data Source
  KAKENHI-PROJECT-21K08649
[Presentation] 当院における高度肥満症に対する減量・代謝改善手術の治療成績.2022
- Author(s)
  齋藤心, 千葉小夜, 春田英律, 小池瑛, 岡田健太, 鈴木昭広 , 橋本愛, 山野井徳,北山丈二 , 細谷好則, 佐田尚宏
- Organizer
  第42回日本肥満学会・第39回日本肥満症治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08740
[Presentation] Flow cytometryを用いた胃癌患者腹腔内免疫細胞の解析2022
- Author(s)
  髙橋和也, 大澤英之, 金丸理人, 倉科憲太郎, 齋藤心, 山口博紀, 細谷好則, 北山丈二,佐田尚宏
- Organizer
  第77回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K08740
[Presentation] 高度肥満症に対する減量・代謝改善手術の治療成績2022
- Author(s)
  齋藤心, 春田英律, 千葉蒔七, 千葉小夜, 小池瑛, 細谷好則, 倉科憲太郎, 岡田健太, 北山丈二,佐田尚宏
- Organizer
  第55回日本成人病（生活習慣病）学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08740
[Presentation] 腹膜播種陽性胃癌に対するパクリタキセル腹腔内投与併用SOX療法の有害事象と治療効果2022
- Author(s)
  齋藤心, 山口博紀, 金丸理人, 高橋和也, 金子勇貴, 松本志郎, 加賀谷丈紘, 風當ゆりえ, 齋藤晶, 大澤英之, 宮戸秀世, 倉科憲太郎, 細谷好則, 北山丈二,佐田尚宏
- Organizer
  第84回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-21K08649
[Presentation] 腹膜播種陽性胃癌に対するパクリタキセル腹腔内投与(IP-PTX)併用SOX療法とConversion Surgeryの治療効果2022
- Author(s)
  齋藤心, 山口博紀, 金丸理人, 大澤英之, 高橋和也, 齋藤晶, 倉科憲太郎, 金子勇貴, 細谷好則, 佐田尚宏,北山丈二
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08649
[Presentation] 減量・代謝改善手術としての腹腔鏡下スリーブ状胃切除術の適応と限界　腹腔鏡下スリーブ状胃切除術の治療成績と改善点.2022
- Author(s)
  齋藤心, 小池瑛 , 春田英律, 千葉蒔七, 岡田健太, 倉科憲太郎,金丸理人,高木徹,高橋和也,金子勇貴, 細谷好則, 北山丈二,佐田尚宏
- Organizer
  第47回日本外科系連合学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08740
[Presentation] The mechanistic analysis of peritoneal dissemination using mouse syngenic gastric cancer cells.2021
- Author(s)
  Yurie Futoh, Hideyo Miyato, Yuki Kaneko, Kohei Tamura, Kazuya Takahashi, Yuki Kimura, Akira Saito, Mineyuki Tojo, Yuko Kumagai, Hiedyuki Ohzawa, Yoshinori Hosoya, Joji Kitayama, Naohiro Sata
- Organizer
  自治医科大学シンポジウム2021
- Data Source
  KAKENHI-PROJECT-21K08740
[Presentation] マウス同種胃がん細胞を用いた腹膜播種の成立機序の検討2021
- Author(s)
  風當ゆりえ, 宮戸秀世, 金子勇貴, 高橋和也, 木村有希, 齋藤晶, 東條峰之, 大澤英之, 細谷好則、北山丈二，佐田尚宏
- Organizer
  第76回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K08740
[Presentation] IP-PTX+SOX療法に奏功を認めた腹膜播種陽性胃癌症例に対するconversoin surgeryの適応と成績2020
- Author(s)
  齋藤心, 山口博紀, 倉科憲太郎, 春田英律, 川平洋, 佐久間康成, 堀江久永, 細谷好則, 佐田尚宏, 北山丈二
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08691
[Presentation] Intraperitoneal Paclitaxel Treatment Conbined with S-1+Oxaliplatin(SOX) for Gastric Cancer with Peritoneal Metastasis.2019
- Author(s)
  Shin Saito., Hironori Yamaguchi., Shiro Matsumoto., Rihito Kanamaru., Kentaro Kurashina., Hidenori Haruta., Yoshinori Hosoya., Sadatomo. Ai, Hirofumi Fujii., Hideyuki Ohzawa., Alan K Lefor., Naohiro Sata., Joji Kitayama.
- Organizer
  14th International Symposium on Regional Cancer Therapies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08691
[Presentation] 胃管癌8例の臨床病理学的検討．2019
- Author(s)
  齋藤　心，細谷　好則，松原　大祐，春田　英律，倉科　憲太郎，松本　志郎，北山　丈二，山口　博紀，佐久間　康成，堀江　久永，佐田　尚宏．
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08691
[Presentation] 腹膜播種陽性胃癌に対するSOX+PTX腹腔内投与併用療法．2019
- Author(s)
  齋藤　心，山口　博紀，細谷　好則，金丸　理人，春田　英律，倉科　憲太郎，堀江　久永，佐久間　康成，佐田　尚宏，北山　丈二．
- Organizer
  第74回日本消化器外科学会
- Data Source
  KAKENHI-PROJECT-18K08691

1. 北山丈二 (20251308)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. 宮戸秀世 (90813163)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
3. 倉科憲太郎 (70382900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. 山口博紀 (20376445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. 佐田友藍 (40528585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Hosoya Yoshinori (30275698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. 春田英律 (20406143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 相澤健一 (70436484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 堀江久永 (20316532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 大澤英之 (60458271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 金丸理人 (10625544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 寺谷工 (70373404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 水上浩明 (20311938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 綿野亮太 (60883915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MATSYBARA Daisuk

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 佐田尚宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Saito Shin 齋藤 心

Research Projects

Research Products

Co-Researchers

Development of novel therapy targeting microRNA for peritoneal dissemination and elucidation of its immunological mechanism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of trogositosis in tumor immune escapePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Oncological significance of vagotomy in upper gastrointestinal surgery

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of smooth muscle cells in invasion and metastasis of scirrhous gastric cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] miR－29b内包エクソソームの腹腔内補充は胃癌腹膜播種を抑制する2023

Author(s)

Journal Title

Data Source

[Journal Article] Intraperitoneal transfer of microRNA‐29b‐containing small extracellular vesicles can suppress peritoneal metastases of gastric cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synopsis of a clinical practice guideline for pancreatic ductal adenocarcinoma with peritoneal dissemination in Japan; Japan Peritoneal Malignancy Study Group.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MiR-29b may suppresses peritoneal metastases through inhibition of the mesothelial?mesenchymal transition (MMT) of human peritoneal mesothelial cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Altered intraperitoneal immune microenvironment in patients with peritoneal metastases from gastric cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Systemic or Intraperitoneal Administration of Anti-PD-1 Antibody for Peritoneal Metastases from Gastric Cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intraperitoneal Administration of Paclitaxel Combined with S-1 Plus Oxaliplatin as Induction Therapy for Patients with Advanced Gastric Cancer with Peritoneal Metastases2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synchronous gastric leiomyoma and intramuscular abdominal wall granular cell tumor with similar imaging features: A case report.2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Eosinophil might be related with the response of peritoneal metastases against intraperitoneal chemotherapy in patients with gastric caner.2023

Author(s)

Organizer

Data Source

[Presentation] Conversion gastrectomy after SOX+intraperitoneal paclitaxel for the patients with peritoneal dissemination from gastric cancer -Outcome analysis by ascites Volume-2023

Author(s)

Organizer

Data Source

[Presentation] Conversion gastrectomy after SOX+intraperitoneal paclitaxel for the patients with peritoneal dissemination from gastric cancer -Outcome analysis by ascites Volume-2023

Author(s)

Organizer

Data Source

[Presentation] Eosinophil might be related with the response of peritoneal metastases against intraperitoneal chemotherapy in patients with gastric caner.2023

Saito Shin 齋藤心

[Presentation] 減量・代謝改善手術としての腹腔鏡下スリーブ状胃切除術の適応と限界　腹腔鏡下スリーブ状胃切除術の治療成績と改善点.2022