Fujii Shinya 藤井晋也

… Alternative Names

藤井晋也フジイシンヤ

FUJII Shinya 藤井晋也

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Researcher Number	60389179
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 薬学部, 教授 2025: 東京科学大学, 総合研究院, 准教授
Affiliation (based on the past Project Information) *help	2023: 東京医科歯科大学, 生体材料工学研究所, 准教授 2019 – 2021: 東京医科歯科大学, 生体材料工学研究所, 准教授 2018: 東京大学, 定量生命科学研究所, 講師 2013 – 2017: 東京大学, 分子細胞生物学研究所, 講師 2012 – 2014: 東京医科歯科大学, 生体材料工学研究所, 助教 … More 2012: 東京医科歯科大学, 疾患生命科学研究部, 助教 2011: 東京医科歯科大学, 大学院疾患生命科学研究部, 助教 2009 – 2010: Tokyo Medical and Dental University, 大学院・疾患生命科学研究部, 助教 2007: Tokyo Medical and Dental University, 大学院・疾患生命科学研究部, 特任助教 2006: 徳島文理大学, 香川薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Drug development chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Medium-sized Section 47:Pharmaceutical sciences and related fields Except Principal Investigator Drug development chemistry / Complex systems
Keywords	Principal Investigator 創薬化学 / リン / 構造活性相関 / ケイ素 / 核内受容体 / 医薬化学 / ホスフィンアミド / 元素化学 / 構造物性相関 / 多元素創薬化学 … More / プロゲステロン / アンドロゲン受容体 / 転写因子 / 医薬品化学 / 有機化学 / 構造展開 / ケミカルスペース / ホスフィンボラン / リン酸アミド / 医薬分子設計 / メタロセン / 多元素有機化合物 / 有機金属化合物 / ホウ素 / 人工翻訳後修飾 / ケミカルバイオロジー / 化学的翻訳後修飾 / 前立腺癌 / クルクミン / ファーマコフォア / PPAR / グルココルチコイド / アンドロゲン / グルココルチコイド受容体 / プロゲステロン受容体 / ステロイドホルモン / 生物活性化合物 / 分配係数 / ゲルマニウム / 疎水性 / 定量的構造活性相関 / エストロゲン / 有機元素化学 / 疎水性相互作用 / ビタミンD / ノンセコステロイド / ホウ素クラスター / 生理活性 / 薬学 … More Except Principal Investigator 核内受容体 / ビタミンK / アンドロゲン受容体 / 薬理シャペロン / 分子設計 / マルチテンプレート / 生理活性物質 / ケイ素 / ブロモドメイン / ハンチンチン / プロテインノックダウン / 阻害剤 / 構造展開 / 核内受容体リガンド / 多重薬理 / 抗腫瘍活性 / SXR / HepG2細胞 / K acid II / K acid I / メナキノン-4 / 抗炎症作用 / 細胞増殖 / 抗炎症効果 / 増殖抑制 / 癌細胞 / 酸化誘導体 / メナキノン / 不飽和脂肪酸 / 結晶構造 / アンドロゲン / プロゲステロン / アダマンタン / ファーマコフォア / 蛍光プローブ / ビタミンD / レチノイド / クマリン / 蛍光センサー / ケイ素含有生理活性物質 / カルシウム濃度制御 / 脂溶性ビタミン / 蛍光性リガンド / 高周期第１４族元素 / カルボラン / 脂溶性ファーマコフォア / 遺伝子転写制御 / 分子認識 / ホウ素クラスター / アンタゴニスト / 疎水性相互作用 / エストロゲン受容体 / 医薬分子設計 / 医薬品化学 Less

Development of novel structural options in medicinal chemistry using phosphorus functionalitiesPrincipal Investigator
- Principal Investigator
  
  藤井晋也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo Medical and Dental University
Phosphinamide as 'the third amide species' in medicinal chemistry - expanding the chemical space of biofunctional moleculesPrincipal Investigator
- Principal Investigator
  
  Fujii Shinya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo Medical and Dental University
Fundamentals of multi-elemental medicinal chemistry for developing the novel and innovative drug candidatesPrincipal Investigator
- Principal Investigator
  
  Fujii Shinya
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
  The University of Tokyo
Development of novel nuclear receptor modulators based on the chemical posttranslational modificationsPrincipal Investigator
- Principal Investigator
  
  Fujii Shinya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
Polypharmacology based on dynamism of the target protein
- Principal Investigator
  
  Hashimoto Yuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
Development of novel transcription modulators based on de novo design of scaffoldsPrincipal Investigator
- Principal Investigator
  
  Fujii Shinya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
Development of novel vitamin K derivatives and elucidation of their biological functions
- Principal Investigator
  
  KAGECHIKA Hiroyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Characterization and application of hydrophobic functionalities bearing heavier group 14 atomsPrincipal Investigator
- Principal Investigator
  
  FUJII Shinya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of specific modulators for nuclear receptors and elucidation of their functions
- Principal Investigator
  
  KAGECHIKA Hiroyuki
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
Development of non-secosteroidal vitamin D receptor ligands based on novel hydrophobic core structurePrincipal Investigator
- Principal Investigator
  
  FUJII Shinya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of Receptor Regulators Utilizing Novel HydrophobicStructure and Its Application for Medicinal Drug Design
- Principal Investigator
  
  ENDO Yasuyuki
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tohoku Pharmaceutical University
イオン間相互作用をファーマコフォアとする次世代ビタミンD受容体リガンドの創製Principal Investigator
- Principal Investigator
  
  藤井晋也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
  Tokushima Bunri University

[Journal Article] Design, Synthesis, and Evaluation of B-(Trifluoromethyl)phenyl Phosphine?Borane Derivatives as Novel Progesterone Receptor Antagonists2024
- Author(s)
  Miyajima Yu、Ochiai Kotaro、Fujii Shinya
- Journal Title
  
  Molecules
  
  Volume: 29 Issue: 7 Pages: 1587-1587
- DOI
  10.3390/molecules29071587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06046
[Journal Article] Structural Development of Androgen Receptor Antagonists Using Phenylferrocene Framework as a Hydrophobic Pharmacophore2024
- Author(s)
  Ochiai Kotaro、Yonezawa Ryo、Fujii Shinya
- Journal Title
  
  ChemMedChem
  
  Volume: 19 Issue: 6
- DOI
  10.1002/cmdc.202400040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ1209, KAKENHI-PROJECT-23K06046
[Journal Article] Physicochemical characterization of B-hydroxyphenyl phosphine borane derivatives and their evaluation as nuclear estrogen receptor ligands2024
- Author(s)
 Miyajima Yu、Noguchi-Yachide Tomomi、Ochiai Kotaro、Fujii Shinya
- Journal Title
 
 RSC Medicinal Chemistry
 
 Volume: 15 Issue: 1 Pages: 119-126
- DOI
 10.1039/d3md00350g
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-23K06046
[Journal Article] Solvent-Dependent Conformational Switching of N-Methyl-N,N'- diarylsquaramide.2023
- Author(s)
  Tanaka.; Takeda,F.; Kanda, M.; Kawahata,M.; Fujii,S.; Katagiri,K.; Masu, H.; Kagechika,H.; Tanatani, A.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 88 Issue: 17 Pages: 12289-12293
- DOI
  10.1021/acs.joc.3c00918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23KK0134, KAKENHI-PROJECT-23K06046
[Journal Article] Development of subtype-selective estrogen receptor modulators using the bis(4-hydroxyphenyl)silanol core as a stable isostere of bis(4-hydroxyphenyl)methanol2023
- Author(s)
  Matsumoto Yuichiro、Hashimoto Yuichi、Fujii Shinya
- Journal Title
  
  RSC Advances
  
  Volume: 13 Issue: 39 Pages: 27359-27362
- DOI
  10.1039/d3ra04656g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06046
[Journal Article] Structural Development of Silicon‐Containing Retinoids: Structure?Activity Relationship Study of the Hydrophobic Pharmacophore of Retinobenzoic Acids Using Silyl Functionalities2022
- Author(s)
  Oikawa Tsuyoshi、Fujii Shinya、Mori Shuichi、Masuno Hiroyuki、Kawachi Emiko、Kagechika Hiroyuki
- Journal Title
  
  ChemMedChem
  
  Volume: in press Issue: 12
- DOI
  10.1002/cmdc.202200176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Design, synthesis and structure?activity relationship of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyisoprop-2-yl)phenylsilane derivatives as liver X receptor agonists2022
- Author(s)
  Namba Nao、Noguchi-Yachide Tomomi、Matsumoto Yuichiro、Hashimoto Yuichi、Fujii Shinya
- Journal Title
  
  Bioorganic and Medicinal Chemistry
  
  Volume: 66 Pages: 116792-116792
- DOI
  10.1016/j.bmc.2022.116792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Design, synthesis and antitumor activity of phthalazine-1,4-dione-based menaquinone analogs2021
- Author(s)
  Fujii Shinya、Miura Takahiro、Oikawa Tsuyoshi、Qin Xian-Yang、Kojima Soichi、Kagechika Hiroyuki
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 43 Pages: 128065-128065
- DOI
  10.1016/j.bmcl.2021.128065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-20K07349
[Journal Article] Structure-property and structure?activity relationships of phenylferrocene derivatives as androgen receptor antagonists2021
- Author(s)
  Ochiai Kotaro、Fujii Shinya
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 46 Pages: 128141-128141
- DOI
  10.1016/j.bmcl.2021.128141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Construction of Aromatic Multilayered Structures Based on the Conformational Properties of N,N’-Dimethylated Squaramide2021
- Author(s)
  Arimura, M.; Tanaka, K.; Kanda, M.; Urushibara, K.; Fujii, S.; Katagiri, K.; Azumaya, I.; Kagechika, H.; Tanatani, A.
- Journal Title
  
  ChemPlusChem
  
  Volume: 86 Issue: 1 Pages: 198-205
- DOI
  10.1002/cplu.202000678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06963, KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Structural Development of Salicylanilide‐Based SPAK Inhibitors as Candidate Antihypertensive Agents2021
- Author(s)
  Fujii Shinya、Kikuchi Eriko、Suzuyama Honoka、Watanabe Yuko、Ishigami‐Yuasa Mari、Masuno Hiroyuki、Mori Takayasu、Isobe Kiyoshi、Uchida Shinichi、Kagechika Hiroyuki
- Journal Title
  
  ChemMedChem
  
  Volume: 16 Issue: 18 Pages: 2817-2822
- DOI
  10.1002/cmdc.202100273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-20K17244, KAKENHI-PROJECT-17H03997
[Journal Article] Synthesis and structure-activity relationship study of 1,12-dicarba-closo-dodecaborane-based triol derivatives as novel nonsecosteroidal vitamin D analogs.2021
- Author(s)
  Fujii, S.; Kano, A.; Sekine R.; Emiko K.; Kagechika, H.
- Journal Title
  
  Heterocycles
  
  Volume: 103 Issue: 1 Pages: 444-444
- DOI
  10.3987/com-20-s(k)30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] リン官能基を用いた創薬化学研究の現状と新たな展開2020
- Author(s)
  藤井晋也
- Journal Title
  
  ファルマシア
  
  Volume: 56 Pages: 406-410
- NAID
  130007841813
- Data Source
  KAKENHI-PROJECT-17H03997
[Journal Article] Phosphine boranes as less hydrophobic building blocks than alkanes and silanes: Structure-property relationship and estrogen-receptor-modulating potency of 4-phosphinophenol derivatives2020
- Author(s)
  Saito Hiroki、Matsumoto Yuichiro、Hashimoto Yuichi、Fujii Shinya
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 4 Pages: 115310-115310
- DOI
  10.1016/j.bmc.2020.115310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03996, KAKENHI-PROJECT-17H03997
[Journal Article] リン官能基を用いた創薬化学研究の現状と新たな展開2020
- Author(s)
  藤井晋也
- Journal Title
  
  ファルマシア
  
  Volume: 56 Pages: 406-410
- NAID
  130007841813
- Data Source
  KAKENHI-PROJECT-19K22486
[Journal Article] Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore2020
- Author(s)
  Koga, H.; Negishi, M.; Kinoshita, M.; Fujii, S.; Mori, S.; Ishigami-Yuasa, M.; Kawachi, E.; Kagechika, H.; Tanatani, A.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 15 Pages: 5584-5584
- DOI
  10.3390/ijms21155584
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06963, KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-18K06572
[Journal Article] Development of Novel AKR1C3 Inhibitors as New Potential Treatment for Castration-Resistant Prostate Cancer2020
- Author(s)
  Endo Satoshi、Oguri Hiroaki、Segawa Jin、Kawai Mina、Hu Dawei、Xia Shuang、Okada Takuya、Irie Katsumasa、Fujii Shinya、Gouda Hiroaki、Iguchi Kazuhiro、Matsukawa Takuo、Fujimoto Naohiro、Nakayama Toshiyuki、Toyooka Naoki、Matsunaga Toshiyuki、Ikari Akira
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 63 Issue: 18 Pages: 10396-10411
- DOI
  10.1021/acs.jmedchem.0c00939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Structural development of N-(4-phenoxyphenyl)benzamide derivatives as novel SPAK inhibitors blocking WNK kinase signaling2020
- Author(s)
  Fujii Shinya、Kikuchi Eriko、Watanabe Yuko、Suzuyama Honoka、Ishigami-Yuasa Mari、Mori Takayasu、Isobe Kiyoshi、Uchida Shinichi、Kagechika Hiroyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 17 Pages: 127408-127408
- DOI
  10.1016/j.bmcl.2020.127408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-20K17244, KAKENHI-PROJECT-17H03997
[Journal Article] Spontaneous chiral resolution of N,N′-diarylsquaramides: Formation of various types of one-handed helical networks during crystallization2019
- Author(s)
  Kanda Midori、Urushibara Ko、Park Soyoung、Fujii Shinya、Masu Hyuma、Katagiri Kosuke、Azumaya Isao、Kagechika Hiroyuki、Tanatani Aya
- Journal Title
  
  Tetrahedron
  
  Volume: 75 Issue: 19 Pages: 2771-2777
- DOI
  10.1016/j.tet.2019.03.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J00036, KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Design, Synthesis and Biological Evaluation of Novel Nonsteroidal Progesterone Receptor Antagonists Based on Phenylamino-1,3,5-triazine Scaffold2019
- Author(s)
  Kaitoh Kazuma、Nakatsu Aki、Mori Shuichi、Kagechika Hiroyuki、Hashimoto Yuichi、Fujii Shinya
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 6 Pages: 566-575
- DOI
  10.1248/cpb.c19-00094
- NAID
  130007657391
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Development of novel lithocholic acid derivatives as vitamin D receptor agonists2019
- Author(s)
  Masuno Hiroyuki、Kazui Yuko、Tanatani Aya、Fujii Shinya、Kawachi Emiko、Ikura Teikichi、Ito Nobutoshi、Yamamoto Keiko、Kagechika Hiroyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 16 Pages: 3674-3681
- DOI
  10.1016/j.bmc.2019.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Development of Boron-Cluster-Based Progesterone Receptor Antagonists Bearing a Pentafluorosulfanyl (SF5) Group2019
- Author(s)
 Mori Shuichi、Tsuemoto Nozomi、Kasagawa Tomoya、Nakano Eiichi、Fujii Shinya、Kagechika Hiroyuki
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 67 Issue: 12 Pages: 1278-1283
- DOI
 10.1248/cpb.c19-00522
- NAID
 130007754093
- ISSN
 0009-2363, 1347-5223
- Year and Date
 2019-12-01
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Design and Synthesis of Cyclohexenyl-p-carborane Derivatives as a New Class of Progesterone Receptor Antagonists2019
- Author(s)
  Kagechika Hiroyuki、Fujii Shinya、Yanagida Naoki、Mori Shuichi、Kawachi Emiko
- Journal Title
  
  HETEROCYCLES
  
  Volume: 99 Issue: 1 Pages: 425-425
- DOI
  10.3987/com-18-s(f)38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03997
[Journal Article] A new LC-MS assay for the quantitative analysis of vitamin K metabolites in human urine2019
- Author(s)
  McDonald Matthew G.、Yeung Catherine K.、Teitelbaum Aaron M.、Johnson Amanda L.、Fujii Shinya、Kagechika Hiroyuki、Rettie Allan E.
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 60 Issue: 4 Pages: 892-899
- DOI
  10.1194/jlr.d087916
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997
[Journal Article] Novel androgen receptor full antagonists: Design, synthesis, and a docking study of glycerol and aminoglycerol derivatives that contain p -carborane cages2018
- Author(s)
  Kaise Asako、Ohta Kiminori、Fujii Shinya、Oda Akifumi、Goto Tokuhito、Endo Yasuyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 13 Pages: 3805-3811
- DOI
  10.1016/j.bmc.2018.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08029, KAKENHI-PROJECT-17K08257, KAKENHI-PROJECT-17H03997
[Journal Article] Efficient Lead Finding, Activity Enhancement and Preliminary Selectivity Control of Nuclear Receptor Ligands Bearing a Phenanthridinone Skeleton2018
- Author(s)
  Nishiyama Yuko、Fujii Shinya、Makishima Makoto、Hashimoto Yuichi、Ishikawa Minoru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 7 Pages: 2090-2090
- DOI
  10.3390/ijms19072090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-18H02551
[Journal Article] Novel Nonsteroidal Progesterone Receptor (PR) Antagonists with a Phenanthridinone Skeleton2018
- Author(s)
  Nishiyama Yuko、Mori Shuichi、Makishima Makoto、Fujii Shinya、Kagechika Hiroyuki、Hashimoto Yuichi、Ishikawa Minoru
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 9 Issue: 7 Pages: 641-645
- DOI
  10.1021/acsmedchemlett.8b00058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-18H02551
[Journal Article] Structure-activity relationship of novel (benzoylaminophenoxy)phenol derivatives as anti-prostate cancer agents2018
- Author(s)
  Kazui Yuko、Fujii Shinya、Yamada Ayumi、Ishigami-Yuasa Mari、Kagechika Hiroyuki、Tanatani Aya
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 18 Pages: 5118-5127
- DOI
  10.1016/j.bmc.2018.09.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-16K08318
[Journal Article] Development of novel silanol-based human pregnane X receptor (PXR) agonists with improved receptor selectivity.2018
- Author(s)
  Toyama H, Shirakawa H, Komai M, Hashimoto Y, Fujii S.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 26 Issue: 15 Pages: 4493-4501
- DOI
  10.1016/j.bmc.2018.07.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03814, KAKENHI-PROJECT-17H03996, KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-16K15137
[Journal Article] Development of biotin-retinoid conjugates as chemical probes for analysis of retinoid function2018
- Author(s)
  Fujii Shinya、Mori Shuichi、Kagechika Hiroyuki、Mendoza Parra Marco Antonio、Gronemeyer Hinrich
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 28 Issue: 14 Pages: 2442-2445
- DOI
  10.1016/j.bmcl.2018.06.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Journal Article] Structural Development of Tetrachlorophthalimides as Liver X Receptor β (LXRβ)-Selective Agonists with Improved Aqueous Solubility2018
- Author(s)
  Sayaka Nomura, Kaori Endo-Umeda, Shinya Fujii, Makoto Makishima, Yuichi Hashimoto, Minoru Ishikawa
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 28 Issue: 4 Pages: 796-801
- DOI
  10.1016/j.bmcl.2017.12.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293027, KAKENHI-PROJECT-17H03996, KAKENHI-PROJECT-17H03997
[Journal Article] Progress in the medicinal chemistry of silicon. -C/Si-Exchange and beyond-2017
- Author(s)
  Fujii, S.,* Hashimoto, Y.
- Journal Title
  
  Future Med. Chem.
  
  Volume: in press Issue: 5 Pages: 485-505
- DOI
  10.4155/fmc-2016-0193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15138, KAKENHI-PROJECT-16K15137, KAKENHI-PROJECT-17H03997
[Journal Article] Development of Novel Hydrophobic Pharmacophores Based on Three-dimensional Molecular Architectures and Elements Chemistry2017
- Author(s)
  藤井晋也
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 137 Issue: 1 Pages: 31-41
- DOI
  10.1248/yakushi.16-00201
- NAID
  130005180853
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2017-01-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15138
[Journal Article] Novel Non-steroidal Progesterone Receptor Ligands Based on m-Carborane Containing a Secondary Alcohol: Effect of Chirality on Ligand Activity2017
- Author(s)
 Mori, S.; Takagaki, R.; Fujii, S.; Urushibara, K.; Tanatani, A.; Kagechika, H.
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 65 Issue: 11 Pages: 1051-1057
- DOI
 10.1248/cpb.c17-00544
- NAID
 130006191500
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-16K08318, KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-16K15138
[Journal Article] Design and synthesis of 1, 3, 5-triazine derivatives as novel inverse agonist of nuclear retinoic acid receptor-related orphan receptor-γ2017
- Author(s)
  Kaitoh. K, Toyama. H, Hashimoto. Y, Fujii. S
- Journal Title
  
  Heterocycles
  
  Volume: 95 Issue: 1 Pages: 547-556
- DOI
  10.3987/com-16-s(s)16
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J07278, KAKENHI-PROJECT-16K15138
[Journal Article] Development of nonsteroidal glucocorticoid receptor modulators based on N -benzyl- N -(4-phenoxyphenyl)benzenesulfonamide scaffold2017
- Author(s)
  Yoshioka Hiromasa、Yamada Ayumi、Nishiyama Yuko、Kagechika Hiroyuki、Hashimoto Yuichi、Fujii Shinya
- Journal Title
  
  Bioorganig and Medicinal Chemistry
  
  Volume: 25 Issue: 13 Pages: 3461-3470
- DOI
  10.1016/j.bmc.2017.04.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03996, KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-16K15138
[Journal Article] 新たなファーマコフォアの創出を基盤としたビタミンD受容体リガンドの創製2017
- Author(s)
  藤井晋也
- Journal Title
  
  ビタミン
  
  Volume: 91 Pages: 28-37
- NAID
  130006694334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15138
[Journal Article] Development of WNK signaling inhibitors as a new class of antihypertensive drugs2017
- Author(s)
  Ishigami-Yuasa Mari、Watanabe Yuko、Mori Takayasu、Masuno Hiroyuki、Fujii Shinya、Kikuchi Eriko、Uchida Shinichi、Kagechika Hiroyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 25 Issue: 14 Pages: 3845-3852
- DOI
  10.1016/j.bmc.2017.05.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-16K15138
[Journal Article] Development of 6-Arylcoumarins as Nonsteroidal Progesterone Antagonists. Structure-activity Relationships and Fluorescence Properties.2016
- Author(s)
  Marie Kinoshita, Mai Negishi, Haruka Sakai, Tomoya Hirano, Shuichi Mori, Shinya Fujii, Hiroyuki Kagechika, Aya Tanatani
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 24 Issue: 21 Pages: 5602-5610
- DOI
  10.1016/j.bmc.2016.09.020
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08019, KAKENHI-PROJECT-16K08318, KAKENHI-PROJECT-16K15138
[Journal Article] Altered activity profile of a tertiary silanol analog of multi-targeting nuclear receptor modulator T09013172016
- Author(s)
  Toyama, H.; Sato, S.; Shirakawa, H.; Komai, M.; Hashimoto, Y.; Fujii, S.*
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 26 Pages: 1817-1820
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460146
[Journal Article] Development of N-(4-phenoxyphenyl)benzenesulfonamide derivatives as novel nonsteroidal progesterone receptor antagonists2016
- Author(s)
  Yamada, A.; Kazui, Y.; Yoshioka, H.; Tanatani, A.; Mori, S.; Kagechika, H.; Fujii, S.
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 7 Issue: 12 Pages: 1028-1033
- DOI
  10.1021/acsmedchemlett.6b00184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08318, KAKENHI-PROJECT-16K15138
[Journal Article] Expanding the chemical space of hydrophobic pharmacophores: Role of hydrophobic substructures in the development of novel transcription modulators2016
- Author(s)
  Fujii, S. *
- Journal Title
  
  Med. Chem. Commum.
  
  Volume: 7 Issue: 6 Pages: 1082-1092
- DOI
  10.1039/c6md00012f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15138
[Journal Article] Altered activity profile of a tertiary silanol analog of multi-targeting nuclear receptor modulator T0901317.2016
- Author(s)
  Toyama H, Sato S, Shirakawa H, Komai M, Hashimoto Y, Fujii, S.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 26 Issue: 7 Pages: 1817-1820
- DOI
  10.1016/j.bmcl.2016.02.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26292063, KAKENHI-PROJECT-26293025
[Journal Article] Development of 1,3-diphenyladamantane derivatives as nonsteroidal progesterone receptor antagonists.2015
- Author(s)
  Mori, S.; Takeuchi, Y.; Tanatani, A.; Kagechika, H.; Fujii, S.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 23 Issue: 4 Pages: 803-809
- DOI
  10.1016/j.bmc.2014.12.047
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-24590137, KAKENHI-PROJECT-25460146
[Journal Article] Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists2015
- Author(s)
  Kazumi Inoue, Ko Urushibara, Misae Kanai, Kei Yura, Shinya Fujii, Mari Ishigami-Yuasa, Yuichi Hashimoto, Shuichi Mori, Emiko Kawachi, Mio Matsumura, Tomoya Hirano, Hiroyuki Kagechika, Aya Tanatani
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 102 Pages: 310-319
- DOI
  10.1016/j.ejmech.2015.08.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08019, KAKENHI-PROJECT-25460146
[Journal Article] Design and synthesis of novel ROR inverse agonists based on dibenzosilole scaffolds as a hydrophobic core structure2015
- Author(s)
  Toyama, H.; Nakamura, M.; Hashimoto, Y.; Fujii, S.*
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 13 Pages: 2982-2988
- DOI
  10.1016/j.bmc.2015.05.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-26293025
[Journal Article] Carboxylic derivatives of vitamin K2 inhibit hepatocellular carcinoma cell growth through caspase/transglutaminase-related signaling pathways2015
- Author(s)
  Qin, X.-Y.; Fujii, S.; Shimizu, A.; Kagechika, H.; Kojima, S.
- Journal Title
  
  J. Nutr. Sci. Vitaminol.
  
  Volume: 61 Pages: 285-290
- NAID
  130005102615
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460146
[Journal Article] Systematic synthesis and anti-inflammatory activity of ω-carboxylated menaquinone derivatives -Investigation on identified and putative vitamin K metabolites-2015
- Author(s)
  Fujii, S.; Shimizu, A.; Takeda, N.; Oguchi, K.; Katsurai, T.; Shirakawa, H.; Komai, M.; Kagechika, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 10 Pages: 2344-2352
- DOI
  10.1016/j.bmc.2015.03.070
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-26292063
[Journal Article] 新規ファーマコフォアの構築に基づくアンドロゲン受容体パンアンタゴニストの創製2015
- Author(s)
  藤井晋也，山田歩，森修一，影近弘之
- Journal Title
  
  ケミカルバイオロジー
  
  Volume: 18 Pages: 6-8
- Data Source
  KAKENHI-PROJECT-25460146
[Journal Article] Design and synthesis of silicon-containing fatty acid amide derivatives as novel peroxisome proliferator-activated receptor (PPAR) agonists2015
- Author(s)
  Daisuke Kajita, Masaharu Nakamura, Yotaro Matsumoto, Minoru Ishikawa, Yuichi Hashimoto and Shinya Fujii
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letter
  
  Volume: 25 Issue: 16 Pages: 3350-3354
- DOI
  10.1016/j.bmcl.2015.05.045
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J12421, KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-25293027, KAKENHI-PROJECT-26293025
[Journal Article] Design and synthesis of tetraol derivatives of 1,12-dicarba-closo-dodecaborane as non-secosteroidal vitamin D analogs.2014
- Author(s)
  Fujii, S.; Kano, A.; Masuno, H.; Songkram, C.; Kawachi, E.; Hirano, T.; Tanatani, A.; Kagechika, H
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Issue: 18 Pages: 4515-4519
- DOI
  10.1016/j.bmcl.2014.07.075
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-24590005, KAKENHI-PROJECT-24590137, KAKENHI-PROJECT-25460146
[Journal Article] 球状疎水性ファーマコフォアを有する非セコステロイド型ＶＤＲリガンドの創製研究2014
- Author(s)
  藤井晋也，棚谷綾，平野智也，影近弘之
- Journal Title
  
  ビタミン
  
  Volume: 88 Pages: 389-395
- NAID
  110009843773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460146
[Journal Article] Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters2014
- Author(s)
  Kikuchi E, Mori T, Zeniya M, Isobe K, Ishigami-Yuasa M, Fujii S, Kagechika H, Ishihara T, Mizushima T, Sasaki S, Sohara E, Rai T, Uchida S
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 26 Issue: 7 Pages: 1525-1536
- DOI
  10.1681/asn.2014060560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-26670428
[Journal Article] Synthesis and structure-activity relationship of p-carborane-based non-secosteroidal vitamin D analogs.2014
- Author(s)
  Fujii, S.; Kano, A.; Songkram, C.; Masuno, H.; Tao da, Y.; Kawachi, E.; Hirano, T.; Tanatani, A.; Kagechika, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 4 Pages: 1227-1235
- DOI
  10.1016/j.bmc.2014.01.015
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-23659051, KAKENHI-PROJECT-24590005, KAKENHI-PROJECT-24590137, KAKENHI-PROJECT-25460146
[Journal Article] Lipase-catalyzed asymmetric acylation of boron cluster-containing secondary alcohols.2014
- Author(s)
  Mori, S.; Takagaki, R.; Fujii, S.; Matsumura, M.; Tanatani, A.; Kagechika, H.
- Journal Title
  
  Tetrahedron Asymm.
  
  Volume: 25 Issue: 23 Pages: 1505-1512
- DOI
  10.1016/j.tetasy.2014.10.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-24590137, KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-26670052
[Journal Article] Development of 2-Thioxoquinazoline-4-one Derivatives as Dual and Selective Inhibitors of Dynamin-Related Protein 1 (Drp1) and Puromycin-Sensitive Aminopeptidase (PSA)2014
- Author(s)
  Numadate, A.; Mita, Y.; Matsumoto, Y.; Fujii, S.; Hashimoto, Y.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 62 Issue: 10 Pages: 979-988
- DOI
  10.1248/cpb.c14-00333
- NAID
  130004693775
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460146
[Journal Article] Development of p-carborane-based nonsteroidal progesterone receptor antagonists.2014
- Author(s)
  Fujii, S.; Nakano, E.; Yanagida, N.; Mori, S.; Masuno, H.; Kagechika, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 19 Pages: 5329-5337
- DOI
  10.1016/j.bmc.2014.07.049
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-25460146
[Journal Article] Synthesis and Structure–Activity Relationship Study of Triazine-Based Inhibitors of the DNA Binding of NF-κB2014
- Author(s)
  Fujii, S.; Kobayashi, T.; Nakatsu, A.; Miyazawa, H.; Kagechika, H.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 62 Issue: 7 Pages: 700-708
- DOI
  10.1248/cpb.c14-00218
- NAID
  130004053804
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-25460146
[Journal Article] Structural development of p-carborane-based potent non-secosteroidal vitamin D analogs.2014
- Author(s)
  Fujii, S.; Sekine, R.; Kano, A.; Masuno, H.; Songkram, C.; Kawachi, E.; Hirano, T.; Tanatani, A.; Kagechika, H.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 22 Issue: 21 Pages: 5891-5901
- DOI
  10.1016/j.bmc.2014.09.020
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-24590005, KAKENHI-PROJECT-24590137, KAKENHI-PROJECT-25460146
[Journal Article] Design and synthesis of nonsteroidal progesterone receptor antagonists based on C,C’-diphenylcarborane scaffold as a hydrophobic pharmacophore.2014
- Author(s)
  Fujii, S.; Yamada, A.; Nakano, E.; Takeuchi, Y.; Mori, S.; Masuno, H.; Kagechika, H.
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 84 Pages: 264-277
- DOI
  10.1016/j.ejmech.2014.07.034
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-25460146
[Journal Article] Increased Hydrophobicity and Estrogenic Activity of Simple Phenols with Silicon and Germanium- Containing Substituents2013
- Author(s)
  Fujii, S.
- Journal Title
  
  J. Med. Chem.
  
  Volume: 56 Issue: 1 Pages: 160-166
- DOI
  10.1021/jm3013757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659051, KAKENHI-PROJECT-23790128, KAKENHI-PLANNED-22136013
[Journal Article] Copper-mediated C-C Cross-Coupling Reaction of Monocarba-closo-dodecaborate Anion for Construction of Functional Molecules2013
- Author(s)
  Junichiro Kanazawa, Ryo Takita, Aleksandra Jankowiak, Shinya Fujii, Hiroyuki Kagechika, Daisuke Hashizume, Koichi Shudo, Piotr Kaszynski, and Masanobu Uchiyama
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 52 Issue: 31 Pages: 8017-8021
- DOI
  10.1002/anie.201302448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229001, KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-25713001
[Journal Article] Design and synthesis of 4-(4-benzoylaminophenoxy)phenol derivatives as androgen receptor antagonists.2013
- Author(s)
  Yamada, A.; Fujii, S.; Mori, S.; Kagechika, H.
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 4 Issue: 10 Pages: 937-941
- DOI
  10.1021/ml4001744
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-23659051, KAKENHI-PROJECT-25460146
[Journal Article] Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy.2013
- Author(s)
  Mori, T.; Kikuchi, E.; Watanabe, Y.; Fujii, S.; Ishigami-Yuasa, M.; Kagechika, H.; Sohara, E.; Rai, T.; Sasaki, S.; Uchida, S.
- Journal Title
  
  Biochem. J.
  
  Volume: 455 Issue: 3 Pages: 339-345
- DOI
  10.1042/bj20130597
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-22249032, KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25460146, KAKENHI-PROJECT-25670406
[Journal Article] Novel vitamin D receptor ligands bearing a spherical hydrophobic core structure-Comparison of bicyclic hydrocarbon derivatives with boron cluster derivatives2012
- Author(s)
  Wongmayura, A.
- Journal Title
  
  Bioorg.Med Chem.Lett.
  
  Volume: 22 Issue: 4 Pages: 1756-1760
- DOI
  10.1016/j.bmcl.2011.12.137
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-23790128, KAKENHI-PROJECT-24590137
[Journal Article] Development of Androgen Recby Application of Ten-vertex p-Carborane as a Novel Hydrophobic Core Structure2012
- Author(s)
  Shinya Fujii, Kiminori Ohta, Tokuhito Goto, Akifumi Oda, Hiroyuki Masuno, Ysuyuki Endo, Hiroyuki Kagechika
- Journal Title
  
  Med. Chem. Commun
  
  Volume: 3 Issue: 6 Pages: 680-684
- DOI
  10.1039/c2md00294a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035, KAKENHI-PROJECT-23659051, KAKENHI-PROJECT-23790128, KAKENHI-PROJECT-23790137, KAKENHI-PROJECT-24790115, KAKENHI-PLANNED-22136013
[Journal Article] p-Carborane Based AndrogenActive in LNCaP Cells with a Mutated Androgen Receptor2011
- Author(s)
  Shinya Fujii, Ayumi Yamada, Keiko Tomita, Mao Nagano, Tokuhito Goto, Kiminori Ohta, Takashi Harayama, Yasuyuki Endo, Hiroyuki Kagechika
- Journal Title
  
  Med. Chem. Commun
  
  Volume: 2 Issue: 9 Pages: 877-880
- DOI
  10.1039/c1md00001b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035, KAKENHI-PROJECT-21790116, KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-23659051, KAKENHI-PROJECT-23790128
[Journal Article] Efficient and diversity-oriented total synthesis of Riccardin C and application to develop novel macrolactam derivatives2011
- Author(s)
  Iwashita, M.
- Journal Title
  
  Tetrahedron
  
  Volume: 67 Issue: 33 Pages: 6073-6082
- DOI
  10.1016/j.tet.2011.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-23659051, KAKENHI-PROJECT-23790128
[Journal Article] Crystal Structure, Docking SStructure-activity Relationship of Carborane-containing Androgen2011
- Author(s)
  Kiminori Ohta, Tokuhito Goto, Synya Fujii, Masatoshi Kawahata, Akifumi Oda, Shigeru Ohta, Kentaro Yamaguchi, Shuichi Hirono,Yasuyuki Endo
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 19 Issue: 11 Pages: 3540-3548
- DOI
  10.1016/j.bmc.2011.04.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035, KAKENHI-PROJECT-21790116, KAKENHI-PROJECT-23790128
[Journal Article] 6-Arylcoumarins as novel nonsteroidal type progesterone antagonists : An example with receptor-binding-dependent fluorescence2011
- Author(s)
  Sakai, H.
- Journal Title
  
  J.Med.Chem.
  
  Volume: 54 Issue: 20 Pages: 7055-7065
- DOI
  10.1021/jm2005404
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-22790106, KAKENHI-PROJECT-23659051, KAKENHI-PROJECT-23790127, KAKENHI-PROJECT-23790128
[Journal Article] Boron Cluster-based DevNon-Secosteroidal Vitamin D Receptor Ligands: Direct Observation of Hydrophobic Interaction between Protein Surface and Carborane2011
- Author(s)
  Shinya Fujii, Hiroyuki Masuno, Yoshiyuki Taoda, Atsushi Kano, Angsuma Wongmayura, Makoto Nakabayashi, Nobutoshi Ito, Masato Shimizu, Emiko Kawachi, Tomoya Hirano, YasuyukiEndo, Aya Tanatani, Hiroyuki Kagechika
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 133 Issue: 51 Pages: 20933-20941
- DOI
  10.1021/ja208797n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035, KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-22790106, KAKENHI-PROJECT-23659051, KAKENHI-PROJECT-23790128
[Journal Article] Synthesis and Biological Activity of Fluorinated Vitamin D.2010
- Author(s)
  Fujishima T., Fujii S., Harayama T.
- Journal Title
  
  Current Organic Chemistry
  
  Volume: 14 Pages: 962-976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Design and Synthesis oReceptor (AR) Antagonists Bearing a p-Carborane Cage: Promising Ligand for Antiandrogen Withdrawal Syndrome2010
- Author(s)
  Tokuhito Goto, Kiminori Ohta, Shinya Fujii, Tomoharu Suzuki, Shigeru Ohta, Yasuyuki Endo
- Journal Title
  
  J. Med. Chem
  
  Volume: 53 Issue: 13 Pages: 4917-4926
- DOI
  10.1021/jm100316f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035, KAKENHI-PROJECT-21790116
[Journal Article] Design and Synthesis of Potent Androgen Receptor (AR) Antagonists Bearing a p-Carborane Cage : Promising Ligand for Antiandrogen Withdrawal Syndrome.2010
- Author(s)
  Goto, T., Ohta, K., Fujii, S., Suzuki, T., Ohta, S., Endo, Y.
- Journal Title
  
  J.Med.Chem. 53
  
  Pages: 4917-4926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035
[Journal Article] Design and synthesis of androgen receptor full antagonists bearing a p-carborane cage : Promising ligands for anti-androgen withdrawal syndrome.2010
- Author(s)
  Goto T., Ohta K., Fujii S., Ohta S., Endo Y.
- Journal Title
  
  Journal of Medicinal-Chemistry
  
  Volume: 53 Pages: 4917-4926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Development of novel androgen antagonists based on hydrophobic boron clusters.2010
- Author(s)
  Fujii S., Yamada A., Ohta K., Endo Y., Kagechika H.
- Journal Title
  
  Drugs of the Future
  
  Volume: 35A Pages: 258-259
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Development of novel androgen antagonists based on hydrophobic boron clusters.2010
- Author(s)
  Shinya Fujii, Ayumi, Yamada, Kiminori Ohta, Yasuyuki Endo, Hiroyuki Kagechika
- Journal Title
  
  Drugs of the Future 35 suppl.A
  
  Pages: 258-259
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Design and synthesis of androgen receptor full antagonists bearing a p-carborane cage : Promising ligands for anti-androgen withdrawal syndrome.2010
- Author(s)
  Tokuhito Goto, Kiminori Ohta, Shinya Fujii, Sigeru Ohta, Yasuyuki Endo
- Journal Title
  
  J.Med.Chem. 53
  
  Pages: 4917-4926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Effect of oxygen substituent in the aniline part of benzanilide on the regioselectivity in direct arylation using palladium-phosphine reagents.2010
- Author(s)
  Takashi Harayama, Mariko Asai, Taeko Miyagoe, Hitoshi Abe, Yasuo Takeuchi, Ayako Yamaguchi, Shinya Fujii
- Journal Title
  
  Heterocycles 81
  
  Pages: 1881-1889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Synthesis and Biological Activity of Fluorinated Vitamin D.2010
- Author(s)
  Toshie Fujishima, Shinya Fujii, Takashi Harayama
- Journal Title
  
  Curr.Org.Chem. 14
  
  Pages: 962-976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Effect of oxygen substituent in the aniline part of benzanilide on the regioselectivity in direct arylation using palladium-phosphine reagents2010
- Author(s)
  Harayama T., Asai M., Miyagoe T., Abe H., Takeuchi Y., Yamaguchi A., Fujii S.
- Journal Title
  
  Heterocyclees
  
  Volume: 81 Pages: 1881-1889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Acidic heterocycles as novel hydrophilic pharmacophore of androgen receptor ligands with a carborane core structure2009
- Author(s)
  Shinya Fujii
- Journal Title
  
  Bioorg. Med. Chem. 17
  
  Pages: 344-350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035
[Journal Article] A novel carborane analog, BE360, with a carbon-containing polyhedral boron-cluster is a new selective estrogen receptor modulator for bone2009
- Author(s)
  Shinya Fujii
- Journal Title
  
  Biochem. Biophys. Res. Commun. 380
  
  Pages: 218-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035
[Journal Article] Acidic heterocycles as novel hydrophilic pharmacophore of androgen receptor ligands with a carborane core structure.2009
- Author(s)
  Shinya Fujii, Kiminori Ohta, Tokuhito Goto, Hiroyuki Kagechika, Yasuyuki Endo
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 344-350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Fluorescent visualization of the conformational change of aromatic amide or urea induced by N-methylation2009
- Author(s)
  Hirano T, Ohsaki T, Fujii S, Komatsu D, Azumaya I, Tanatani A, Kagechika H
- Journal Title
  
  Tetrahedron Letters 50
  
  Pages: 488-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Journal Article] Synthesis and Biological Evaluation of p-Carborane Bisphenols anf Their Derivatives : Structure-Activity Relationship for Estrogenic Activity2009
- Author(s)
  Shinya Fujii
- Journal Title
  
  Bioorg. Med. Chem. 17
  
  Pages: 1109-1117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035
[Journal Article] Acidic heterocycles as novel hydrophilic pharmacophore of androgen receptor ligands with a carborane core structure2009
- Author(s)
  Shinya Fujii, Kiminori Ohta, TokuhitoGoto, Hiroyuki Kagechika, Yasuyuki Endo
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 17 Issue: 1 Pages: 344-350
- DOI
  10.1016/j.bmc.2008.10.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035, KAKENHI-PROJECT-21790116
[Journal Article] Identification of an intermediate in the deboronation of ortho-carborane: an adduct of ortho-carborane with two nucleophiles on one boron atom2008
- Author(s)
  Yoshiyuki Taoda, Takehiko Sawabe, Yasuyuki Endo, Kentaro Yamaguchi, Shinya Fujii, Hiroyuki Kagechika
- Journal Title
  
  Chem. Commun
  
  Issue: 17 Pages: 2049-2051
- DOI
  10.1039/b716079h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390035
[Journal Article] Potent androgen antagonists based on carborane as a hydrophobic core structure2007
- Author(s)
  Fujii, S., Ohta, K., Goto, T., Hashimoto, Y., Suzuki, T., Ohta, S., Endo, Y.
- Journal Title
  
  Drugs of the Future 32 Suppl.A
  
  Pages: 105-106
- Data Source
  KAKENHI-PROJECT-18790094
[Journal Article] Methyl-introduced A-ring analogues of 1α,25-dihydroxyvitamin D_3 : Synthesis and biological evaluation2006
- Author(s)
  Toshie Fujishima, Ryuji Tsutsumi, Yoichi Negishi, Shinya Fujii, Hiroaki Takayama, Atsushi Kittaka, Masaaki Kurihara
- Journal Title
  
  Anticancer Research 26
  
  Pages: 2633-2636
- Data Source
  KAKENHI-PROJECT-18790094
[Journal Article] Crystal structure, docking study and structure-activity relationship of carborane-containing androgen receptor antagonist 3-(12-hydroxymethyl-1,12-dicarba- closo-do decaboran-1-yl)benzonitrile.
- Author(s)
  Kiminori Ohta, Tokuhito Goto, Shinya Fujii, Masatoshi Kawahata, Akifumi Oda, Shigeru Ohta, Kentaro Yamaguchi, Shuichi Hirono, Yasuyuki Endo
- Journal Title
  
  Bioorg.Med.Chem. in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790110
[Patent] 新規アンドロゲン受容体アンタゴニスト2013
- Inventor(s)
  影近弘之、藤井晋也、山田歩
- Industrial Property Rights Holder
  影近弘之、藤井晋也、山田歩
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-28
- Overseas
- Data Source
  KAKENHI-PROJECT-23790128
[Patent] 新規アンドロゲン受容体アンタゴニスト2012
- Inventor(s)
  影近弘之、藤井晋也、山田歩
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Number
  2012-043959
- Filing Date
  2012
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] フェニルフェロセンを疎水性骨格に用いたアンドロゲン受容体アンタゴニストの構造活性2024
- Author(s)
  米澤亮、落合幸太郎、影近弘之、藤井晋也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] B-ヒドロキシフェニルホスフィンボラン誘導体の構造物性相関とERリガンド活性2024
- Author(s)
  宮島友，谷内出友美，影近弘之，藤井晋也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] Structure-activity relationship (SAR) study of hydrophobic moiety of nonsecosteroidal VDR ligands using diphenylsilane scaffold2024
- Author(s)
  N. M. Hansaka N. Thilakarathne, Takashi Misawa, Yosuke Demizu, Yuya Hanazono, Nobutoshi Ito, Hiroyuki Kagechika, Shinya Fujii
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] Ferrocene as a Three-Dimensional Platform for Molecular Building: Development of Ferrocene-Based Nuclear Receptor Ligands2023
- Author(s)
  Ochiai, K., Kagechika, H., Fujii, S.
- Organizer
  International Chemical Biology Society (ICBS2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] B-ヒドロキシフェニルホスフォンボランの合成と構造物性相関およびERリガンド活性2023
- Author(s)
  宮島友，谷内出友美，影近弘之，藤井晋也
- Organizer
  第49回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] P－B Bond as a Novel Structural Option in Medicinal Chemists' Toolbox: Physicochemical Properties and Estrogenic Activity of Phosphine Borane-Based Phenols.2023
- Author(s)
  Fujii, S., Miyajima, Y., Noguchi-Yachide, T., Saito, H., Kagechika, H.
- Organizer
  24th International Conference on Phosphorus Chemistry (ICPC24)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] ヒドロホウ素化によるシリルエタノール合成の位置選択性と疎水性部分構造としての応用2023
- Author(s)
  難波奈央，影近弘之，藤井晋也
- Organizer
  第49回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] Development of Androgen Receptor Antagonist by Bioisosteric Replacement of Hydrophobic Pharmacophore with Ferrocene.2023
- Author(s)
  Ochiai, K., Kagechika, H., Fujii, S.
- Organizer
  第69回有機金属化学討論会
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] Phosphineboranes as Novel Options in Medicinal Chemists' Toolbox: Physicochemical Properties and Estrogenic Activity of B-(Hydroxyphenyl)phosphineborane Derivatives.2023
- Author(s)
  Fujii, S., Miyajima, Y., Noguchi-Yachide, T., Kagechika, H.
- Organizer
  14th AFMC International Medicinal Chemistry Symposium (AIMECS 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] Physicochemical Properties and Estrogenic Activity of B-Hydroxyphenyl Phosphine Borane Derivatives: Phosphine Boranes as Novel Structural Options of Functional Molecules.2023
- Author(s)
  Fujii, S., Miyajima, Y., Noguchi-Yachide, T., Kagechika, H.
- Organizer
  The 8th International Symposium on Biomedical Engineering (ISBE2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] 創薬化学における元素多様化の試み2023
- Author(s)
  藤井晋也
- Organizer
  第10回バイオ関連化学シンポジウム若手フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] フェロセンを三次元プラットフォーム構造として用いた核内受容体リガンドの創製2023
- Author(s)
  落合幸太郎，影近弘之，藤井晋也
- Organizer
  第40回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] Development of Progesterone Receptor Antagonists Using Ferrocene as a Three-Dimensional Platform Structure2023
- Author(s)
  Ochiai, K., Kagechika, H., Fujii, S.
- Organizer
  The 8th International Symposium on Biomedical Engineering (ISBE2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] リン‐ホウ素結合を活用した生物活性化合物の創製－ホスフィンボランを基盤とするERリガンドの構造展開－2023
- Author(s)
  宮島友，谷内出友美，影近弘之，藤井晋也
- Organizer
  日本ケミカルバイオロジー学会第17回年会
- Data Source
  KAKENHI-PROJECT-23K06046
[Presentation] 含ケイ素化合物の構造展開によるLXRβ選択的リガンドの創製2022
- Author(s)
  難波奈央，谷内出友美，松本雄一朗，橋本祐一，影近弘之，藤井晋也．
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 含ケイ素化合物の構造展開によるLXRβ選択的リガンドの創製2022
- Author(s)
  難波奈央，谷内出友美，松本雄一朗，橋本祐一，影近弘之，藤井晋也．
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] 二置換フェロセン誘導体の構造展開による新規アンドロゲン受容体アンタゴニストの創製2022
- Author(s)
  落合幸太郎，影近弘之，藤井晋也．
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] 二置換フェロセン誘導体の構造展開による新規アンドロゲン受容体アンタゴニストの創製2022
- Author(s)
  落合幸太郎，影近弘之，藤井晋也．
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 疎水性構造としてフェロセンを有する新規ARアンタゴニストの創製2021
- Author(s)
  落合幸太郎，影近弘之，藤井晋也．
- Organizer
  日本レチノイド研究会第32回学術集会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ビタミンK を構造基盤とした抗腫瘍化合物の創製研究2021
- Author(s)
  藤井晋也
- Organizer
  日本ビタミン学会第73回大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Structure Development of Silicon-Containing Derivatives of T0901317 as Novel Liver X Receptor (LXR) Ligands.2021
- Author(s)
  Namba, N., Matsumoto, Y., Hashimoto, Y., Noguchi-Yachide, T., Kagechika, H., Fujii, S.
- Organizer
  The 6th International Symposium on Biomedical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] フェロセンを疎水性ファーマコフォアとする核内受容体リガンドの創製2021
- Author(s)
  落合幸太郎，影近弘之，藤井晋也
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] サブタイプ選択的LXRリガンドを指向したケイ素化合物の構造展開．2021
- Author(s)
  難波奈央，松本雄一朗，橋本祐一，谷内出友美，影近弘之，藤井晋也．
- Organizer
  日本レチノイド研究会第32回学術集会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] アンドロゲン受容体リガンドを指向した二置換フェロセン誘導体の設計・合成と構造活性相関．2021
- Author(s)
  落合幸太郎，影近弘之，藤井晋也．
- Organizer
  第47回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Development of silanol-based bisphenols as subtype-selective estrogen receptor modulators.2021
- Author(s)
  Fujii, S., Matsumoto, Y., Hashimoto, Y.
- Organizer
  19th International Symposium on Silicon Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Structure Development of Silicon-Containing Derivatives of T0901317 as Novel Liver X Receptor (LXR) Ligands.2021
- Author(s)
  Namba, N., Matsumoto, Y., Hashimoto, Y., Noguchi-Yachide, T., Kagechika, H., Fujii, S.
- Organizer
  The 6th International Symposium on Biomedical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Systematic investigation of the structure-property and structure-activity relationships of 4-phosphinophenol derivatives: Throwing light on the potential utility of phosphorus in drug discovery.2021
- Author(s)
  Fujii, S., Saito, H., Matsumoto, Y., Hashimoto, Y., Kagechika, H.
- Organizer
  The 6th International Symposium on Biomedical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] フェロセンを疎水性ファーマコフォアとする核内受容体リガンドの創製2021
- Author(s)
  落合幸太郎，影近弘之，藤井晋也
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Development of silanol-based bisphenols as subtype-selective estrogen receptor modulators.2021
- Author(s)
  Fujii, S., Matsumoto, Y., Hashimoto, Y.
- Organizer
  19th International Symposium on Silicon Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] 疎水性構造としてフェロセンを用いたアンドロゲン受容体リガンドの創製．2021
- Author(s)
  落合幸太郎，影近弘之，藤井晋也．
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 非汎用元素を用いた生物活性化合物の分子設計戦略2021
- Author(s)
  藤井晋也
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Development of Androgen Receptor Ligands Bearing Ferrocene as the Hydrophobic Pharmacophore.2021
- Author(s)
  Ochiai, K., Kagechika, H., Fujii S.
- Organizer
  AFMC International Medicinal Chemistry Symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Design, Synthesis and Evaluation of Novel Androgen Receptor Ligand Bearing Ferrocene as the Hydrophobic Pharmacophore2021
- Author(s)
  Ochiai, K., Kagechika, H., Fujii, S.
- Organizer
  The 6th International Symposium on Biomedical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Systematic investigation of the structure-property and structure-activity relationships of 4-phosphinophenol derivatives: Throwing light on the potential utility of phosphorus in drug discovery.2021
- Author(s)
  Fujii, S., Saito, H., Matsumoto, Y., Hashimoto, Y., Kagechika, H.
- Organizer
  The 6th International Symposium on Biomedical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] N-メチル-N,N'-ジフェニルスクアルアミドの立体特性2021
- Author(s)
  田中希実子，神田翠，藤井晋也，影近弘之，棚谷綾
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ケイ素官能基を用いたサブタイプ選択的LXRリガンドの創製研究．2021
- Author(s)
  難波奈央，松本雄一朗，橋本祐一，谷内出友美，影近弘之，藤井晋也．
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] ケイ素官能基を用いたサブタイプ選択的LXRリガンドの創製研究．2021
- Author(s)
  難波奈央，松本雄一朗，橋本祐一，谷内出友美，影近弘之，藤井晋也．
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] サブタイプ選択的LXRリガンドを指向したケイ素化合物の構造展開．2021
- Author(s)
  難波奈央，松本雄一朗，橋本祐一，谷内出友美，影近弘之，藤井晋也．
- Organizer
  日本レチノイド研究会第32回学術集会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] アンドロゲン受容体リガンドを指向した二置換フェロセン誘導体の設計・合成と構造活性相関．2021
- Author(s)
  落合幸太郎，影近弘之，藤井晋也．
- Organizer
  第47回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] N-メチル-N,N'-ジフェニルスクアルアミドの立体特性2021
- Author(s)
  田中希実子，神田翠，藤井晋也，影近弘之，棚谷綾
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Design, Synthesis and Evaluation of Novel Androgen Receptor Ligand Bearing Ferrocene as the Hydrophobic Pharmacophore2021
- Author(s)
  Ochiai, K., Kagechika, H., Fujii, S.
- Organizer
  The 6th International Symposium on Biomedical Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Development of Subtype-Selective Liver X Receptor (LXR) Ligands Using Silicon Functionalities.2021
- Author(s)
  Namba, N., Matsumoto, Y., Hashimoto, Y., Noguchi-Yachide, T., Kagechika, H., Fujii S.
- Organizer
  AFMC International Medicinal Chemistry Symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 疎水性構造としてフェロセンを有する新規ARアンタゴニストの創製2021
- Author(s)
  落合幸太郎，影近弘之，藤井晋也．
- Organizer
  日本レチノイド研究会第32回学術集会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] 疎水性構造としてフェロセンを用いたアンドロゲン受容体リガンドの創製．2021
- Author(s)
  落合幸太郎，影近弘之，藤井晋也．
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Development of Subtype-Selective Liver X Receptor (LXR) Ligands Using Silicon Functionalities.2021
- Author(s)
  Namba, N., Matsumoto, Y., Hashimoto, Y., Noguchi-Yachide, T., Kagechika, H., Fujii S.
- Organizer
  AFMC International Medicinal Chemistry Symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] 非汎用元素を用いた生物活性化合物の分子設計戦略2021
- Author(s)
  藤井晋也
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Development of Androgen Receptor Ligands Bearing Ferrocene as the Hydrophobic Pharmacophore.2021
- Author(s)
  Ochiai, K., Kagechika, H., Fujii S.
- Organizer
  AFMC International Medicinal Chemistry Symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ビタミンK を構造基盤とした抗腫瘍化合物の創製研究2021
- Author(s)
  藤井晋也
- Organizer
  日本ビタミン学会第73回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] ケイ素官能基を利用したレチノイドの疎水性部位の構造展開2020
- Author(s)
  及川剛志，藤井晋也，増野弘幸，河内恵美子，森修一，影近弘之
- Organizer
  日本ビタミン学会第72回大会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] シリル基を利用したレチノイド誘導体の疎水性部位に関する構造活性相関2020
- Author(s)
  藤井晋也，及川剛志，増野弘幸，河内恵美子，森修一，影近弘之
- Organizer
  日本レチノイド研究会第31回学術集会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ケイ素官能基を利用したレチノイドの疎水性部位の構造展開2020
- Author(s)
  及川剛志，藤井晋也，増野弘幸，河内恵美子，森修一，影近弘之
- Organizer
  日本ビタミン学会第72回大会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ベンゼンスルホンアミドを基盤とした非ステロイド型プロゲステロン受容体リガンドの構造展開2020
- Author(s)
  大谷和暉、山田歩、森修一、藤井晋也、影近弘之
- Organizer
  日本薬学会第 140年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] ベンゼンスルホンアミドを基盤とした非ステロイド型プロゲステロン受容体リガンドの構造展開2020
- Author(s)
  大谷和暉、山田歩、森修一、藤井晋也、影近弘之
- Organizer
  日本薬学会第 140年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] シリル基を利用したレチノイド誘導体の疎水性部位に関する構造活性相関2020
- Author(s)
  藤井晋也，及川剛志，増野弘幸，河内恵美子，森修一，影近弘之
- Organizer
  日本レチノイド研究会第31回学術集会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] リン原子の創出する構造多様性に着目した生物活性化合物の創製研究－ホスフィノフェノール誘導体の構造物性相関とERリガンド活性－2019
- Author(s)
  齊藤広樹、松本雄一朗、橋本祐一、藤井晋也
- Organizer
  日本ケミカルバイオロジー学会　第14回年会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Development of novel silicon-containing transcription modulators including sila-heterocyclic compounds2019
- Author(s)
  Hirozumi Toyama, Daisuke Kajita, Yuichi Hashimoto, Shinya Fujii
- Organizer
  BioHeterocycles 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] アンドロゲン合成酵素を標的とした新規去勢抵抗性前立腺がん治療薬の開発2019
- Author(s)
  遠藤智史、瀬川仁、小栗弘成、夏爽、胡大イ、入江克雅、藤井晋也、合田浩明、松川卓生、藤本直浩、中山敏幸、豊岡尚樹、松永俊之、五十里彰
- Organizer
  第47回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] 抗腫瘍活性を有するフタラジンジオン誘導体の創製2019
- Author(s)
  内藤加菜、及川剛志、藤井晋也、秦咸陽、小嶋聡一、影近弘之
- Organizer
  日本レチノイド研究会第30回学術集会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Phosphorus functionalities as novel options for structural development - Properties and estrogenic activity of 4-phosphinophenol derivatives -2019
- Author(s)
  Hiroki Saito, Yuichiro Matsumoto, Hiroyuki Kagechika, Yuichi Hashimoto, Shinya Fujii
- Organizer
  ASMC 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ジフェニルホスフィン構造を基盤とした含リン化合物の性質の解明と医薬品構造要素としての有用性の検討2019
- Author(s)
  齊藤広樹、松本雄一朗、橋本祐一、影近弘之、藤井晋也
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Boron cluster-based development of novel nuclear receptor modulators2019
- Author(s)
  Shinya Fujii
- Organizer
  ICPAC2019 Yangon
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] アンドロゲン合成酵素を標的とした新規去勢抵抗性前立腺がん治療薬の開発2019
- Author(s)
  遠藤智史、瀬川仁、小栗弘成、夏爽、胡大イ、入江克雅、藤井晋也、合田浩明、松川卓生、藤本直浩、中山敏幸、豊岡尚樹、松永俊之、五十里彰
- Organizer
  第47回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 多元素有機化合物の特性を活用した生物活性化合物の創製研究2019
- Author(s)
  藤井晋也
- Organizer
  第45回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] リン原子の創出する構造多様性に着目した生物活性化合物の創製研究－ホスフィノフェノール誘導体の構造物性相関とERリガンド活性－2019
- Author(s)
  齊藤広樹、松本雄一朗、橋本祐一、藤井晋也
- Organizer
  日本ケミカルバイオロジー学会　第14回年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 多元素有機化合物の特性を活用した生物活性化合物の創製研究2019
- Author(s)
  藤井晋也
- Organizer
  第45回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ジフェニルホスフィン構造を基盤とした含リン化合物の性質の解明と医薬品構造要素としての有用性の検討2019
- Author(s)
  齊藤広樹、松本雄一朗、橋本祐一、影近弘之、藤井晋也
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 脂溶性ビタミンをリードとした創薬化学研究～新規骨格構造を有するビタミン誘導体の創製と生物活性～2019
- Author(s)
  藤井晋也、影近弘之
- Organizer
  第363回脂溶性ビタミン総合研究委員会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Development of novel silicon-containing transcription modulators including sila-heterocyclic compounds2019
- Author(s)
  Hirozumi Toyama, Daisuke Kajita, Yuichi Hashimoto, Shinya Fujii
- Organizer
  BioHeterocycles 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Boron cluster-based development of novel nuclear receptor modulators2019
- Author(s)
  Shinya Fujii
- Organizer
  ICPAC2019 Yangon
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] 脂溶性ビタミンをリードとした創薬化学研究～新規骨格構造を有するビタミン誘導体の創製と生物活性～2019
- Author(s)
  藤井晋也、影近弘之
- Organizer
  第363回脂溶性ビタミン総合研究委員会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Phosphorus functionalities as novel options for structural development - Properties and estrogenic activity of 4-phosphinophenol derivatives -2019
- Author(s)
  Hiroki Saito, Yuichiro Matsumoto, Hiroyuki Kagechika, Yuichi Hashimoto, Shinya Fujii
- Organizer
  ASMC 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] 抗腫瘍活性を有するフタラジンジオン誘導体の創製2019
- Author(s)
  内藤加菜、及川剛志、藤井晋也、秦咸陽、小嶋聡一、影近弘之
- Organizer
  日本レチノイド研究会第30回学術集会
- Data Source
  KAKENHI-PROJECT-19K22486
[Presentation] Silyl groups as fancy isosteres of cis-diatomic functionalities ―Development of novel nuclear receptor modulators based on silyl functionalities－2018
- Author(s)
  〇Shinya Fujii, Hirozumi Toyama, Daisuke Kajita, Yuichi Hashimoto
- Organizer
  RICT2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Structure-property and structure-activity relationships of heteroatom (Si, P, S)-containing bisphenols2018
- Author(s)
  Yuichiro Matsumoto, Hiroki Saito, Yuichi Hashimoto, 〇Shinya Fujii
- Organizer
  ICPC22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 創薬化学における高周期元素の利用法の検討種々の元素をリンカー構造に有するビスフェノール誘導体の構造物性相関および構造活性相関2018
- Author(s)
  〇松本雄一朗, 橋本祐一, 藤井晋也
- Organizer
  日本レチノイド研究会第29回学術集会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] レチノイド標的遺伝子のゲノムワイドな解析を指向したChem-seqプローブの創製研究2018
- Author(s)
  〇藤井晋也，森修一，影近弘之，Marco Antonio Mendoza Parra，Hinrich Gronemeyer
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Development of chemical probes designed for genome-wide analysis of retinoid targets2018
- Author(s)
  Fujii, S.; Mori, S.; Kagechika, H.; Mendpza Parra, M. A.; Gronemeyer, H.
- Organizer
  JSPS Core-to-core Program Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] Development of chemical probes designed for genome-wide analysis of retinoid targets2018
- Author(s)
  Fujii, S.; Mori, S.; Kagechika, H.; Mendpza Parra, M. A.; Gronemeyer, H.
- Organizer
  JSPS Core-to-core Program Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ビスフェノール構造を基盤としたケイ素官能基の構造物性および構造活性相関2018
- Author(s)
  松本雄一朗、橋本祐一、藤井晋也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ケイ素官能基をリンカー構造とするビスフェノール誘導体の構造物性相関と選択的エストロゲン受容体モジュレータへの展開2018
- Author(s)
  〇松本雄一朗, 橋本祐一, 藤井晋也
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 核内受容体リガンドの疎水性構造の研究～ケイ素含有化合物の構造展開～2018
- Author(s)
  〇藤井晋也、橋本祐一、影近弘之
- Organizer
  第359回脂溶性ビタミン総合研究委員会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ホスフィノフェノール構造を基盤とする含リン化合物の構造物性相関と生物活性化合物への応用2018
- Author(s)
  〇齊藤広樹、松本雄一朗、橋本祐一、藤井晋也
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ビスフェノール構造を基盤としたケイ素官能基の構造物性および構造活性相関2018
- Author(s)
  松本雄一朗、橋本祐一、藤井晋也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] ビタミンD活性を有するカルボラン含有カルボン酸誘導体2018
- Author(s)
  塚本理穂、増野弘幸、藤井晋也、河内恵美子、影近弘之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ビタミンD活性を有するカルボラン含有カルボン酸誘導体2018
- Author(s)
  塚本理穂、増野弘幸、藤井晋也、河内恵美子、影近弘之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] Silanol as a characteristic hydrophilic pharmacophore - Altered activity profile of a silanol analogue of multi-targeting nuclear receptor modulator T0901317 -2018
- Author(s)
  〇Shinya Fujii, Hirozumi Toyama, Yuichi Hashimoto
- Organizer
  EFMC-ISMC 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] m-カルボランを疎水性骨格とした新規プロゲステロン受容体リガンドの創製2017
- Author(s)
  森修一、高垣亮平、藤井晋也、棚谷綾、影近弘之
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] レチノイド標的遺伝子のゲノムワイドな探索を指向した低分子プローブの創製研2017
- Author(s)
  藤井晋也，森修一，影近弘之, Marco Antonio Mendoza Parra, Hinrich Gronemeyer
- Organizer
  日本レチノイド研究会第２８回学術集会
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] Phenanthridin-6(5H)-one骨格を有する非ステロイド型プロゲステロン受容体拮抗薬の創製2017
- Author(s)
  西山郵子、森修一、槇島誠、藤井晋也、影近弘之、橋本祐一、石川稔
- Organizer
  日本レチノイド研究会第２８回学術集会
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] Application of Boron Clusters in Medicinal Chemistry2017
- Author(s)
  Fujii, S.
- Organizer
  17th International Conference on Heterocycles in Bioorganic Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] m-カルボランを疎水性骨格とした新規プロゲステロン受容体リガンドの創製2017
- Author(s)
  森修一、高垣亮平、藤井晋也、棚谷綾、影近弘之
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] ベンズアニリドを骨格に持つ新規芳香族炭化水素受容体リガンドの創製2017
- Author(s)
  岩下涼平、藤井晋也、湯浅磨里、河内恵美子、影近弘之
- Organizer
  日本薬学会第１３７年会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] 種々のケイ素含有置換基を有する新規レチノイドの創製2017
- Author(s)
  及川剛志、藤井晋也、増野弘幸、河内恵美子、影近弘之
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] Medicinal chemistry of silicon and development of silicon-containing biologically active lipids2017
- Author(s)
  Fujii, S.
- Organizer
  University of Strasbourg-RIKEN Workshop on Membrane Lipodology.
- Place of Presentation
  Strasbourg, France
- Year and Date
  2017-03-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] Phenanthridin-6(5H)-one骨格を有する非ステロイド型プロゲステロン受容体拮抗薬の創製2017
- Author(s)
  西山郵子、森修一、槇島誠、藤井晋也、影近弘之、橋本祐一、石川稔
- Organizer
  日本レチノイド研究会第２８回学術集会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] Application of Boron Clusters in Medicinal Chemistry2017
- Author(s)
  Fujii, S.
- Organizer
  17th International Conference on Heterocycles in Bioorganic Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] レチノイド標的遺伝子のゲノムワイドな探索を指向した低分子プローブの創製研2017
- Author(s)
  藤井晋也，森修一，影近弘之, Marco Antonio Mendoza Parra, Hinrich Gronemeyer
- Organizer
  日本レチノイド研究会第２８回学術集会
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 種々のケイ素含有置換基を有する新規レチノイドの創製2017
- Author(s)
  及川剛志、藤井晋也、増野弘幸、河内恵美子、影近弘之
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17H03997
[Presentation] 非環式レチノイド様肝細胞癌選択的殺細胞作用を有する食品由来化合物の探索2016
- Author(s)
  秦咸陽、和田昭盛、藤井晋也、影近弘之、小嶋聡一
- Organizer
  日本ケミカルバイオロジー学会第１１回年会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] AF-1領域による機能制御を指向した新規アンドロゲン受容体モジュレーターの創製2016
- Author(s)
  沼館慧剛、谷内出友美、梅田香織、槇島誠、橋本祐一、藤井晋也
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] 新たな構造基盤を有するビタミンD受容体リガンドの創製2016
- Author(s)
  藤井晋也
- Organizer
  日本ビタミン学会第６８回大会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] 種々のケイ素含有置換基を有する新規レチノイドの創製2016
- Author(s)
  及川剛志、藤井晋也、増野弘幸、河内恵美子、影近弘之
- Organizer
  日本レチノイド研究会第２７回学術集会
- Place of Presentation
  昭和薬科大学（東京都・町田市）
- Year and Date
  2016-10-22
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] ベンゼンスルホンアミドを基盤骨格とした非ステロイド型GRリガンドの創製2016
- Author(s)
  吉岡広大、西山郵子、山田歩、影近弘之、橋本祐一、藤井晋也
- Organizer
  日本レチノイド研究会第２７回学術集会
- Place of Presentation
  昭和薬科大学（東京都・町田市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] 種々のケイ素含有置換基を有する新規レチノイドの創製2016
- Author(s)
  及川剛志、藤井晋也、増野弘幸、河内恵美子、影近弘之
- Organizer
  日本ビタミン学会第６８回大会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] ベンゼンスルホンアミドを基盤とする新規非ステロイド型GRリガンドの創製2016
- Author(s)
  吉岡広大、西山郵子、山田歩、影近弘之、橋本祐一、藤井晋也
- Organizer
  日本ケミカルバイオロジー学会第１１回年会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] 新規芳香族炭化水素受容体リガンドの創製と構造展開2016
- Author(s)
  岩下涼平、藤井晋也、影近弘之
- Organizer
  日本レチノイド研究会第２７回学術集会
- Place of Presentation
  昭和薬科大学（東京都・町田市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] Development of nuclear receptor ligands based on the novel hydrophobic pharmacophore2016
- Author(s)
  Shinya Fujii
- Organizer
  Advances in Retinoids research.
- Place of Presentation
  Strasbourg, France
- Year and Date
  2016-01-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] AF-1領域による機能制御を指向した新規アンドロゲン受容体モジュレーターの創製2016
- Author(s)
  沼館慧剛，谷内出友美，梅田香織，槇島誠，橋本祐一，藤井晋也
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] 核内受容体リガンドを指向した1,3,5-トリアジン誘導体の設計と構造展開2016
- Author(s)
  海東和麻、谷内出友美、中津亜紀、森修一、橋本祐一、影近弘之、藤井晋也
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] 核内受容体リガンドを指向した1,3,5-トリアジン誘導体の設計と構造展開2016
- Author(s)
  海東和麻，谷内出友美，中津亜紀，森修一，橋本祐一，影近弘之，藤井晋也
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] Development of m-carborane-based progesterone receptor ligands and their optical resolution by lipase reaction2016
- Author(s)
  Mori, S.; Takagaki, R.; Fujii, S.; Matsumura, M.; Tanatani, A.; Kagechika, H.
- Organizer
  International Symposium on Biomedical Engineering
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] アンドロゲン受容体AF-1モジュレーターの構造展開2016
- Author(s)
  沼館慧剛、谷内出友美、梅田香織、槇島誠、橋本祐一、藤井晋也
- Organizer
  日本ケミカルバイオロジー学会第１１回年会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] ベンゼンスルホンアミドを基盤とした新規GRリガンドの創製2016
- Author(s)
  吉岡広大、西山郵子、山田歩、影近弘之、橋本祐一、藤井晋也
- Organizer
  第６０回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] 新規アンドロゲン受容体AF-1モジュレーターの構造展開2016
- Author(s)
  沼館慧剛、梅田香織、槇島誠、橋本祐一、藤井晋也
- Organizer
  日本レチノイド研究会第２７回学術集会
- Place of Presentation
  昭和薬科大学（東京都・町田市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] 新規疎水性ファーマコフォアを有するビタミンD受容体リガンドの創製2016
- Author(s)
  藤井晋也、平野智也、棚谷綾、影近弘之
- Organizer
  第２回Neo VitaminD Workshop学術集会
- Place of Presentation
  TKP品川カンファレンスセンター（東京都・港区）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] 新規骨格を有する非セコステロイド型ビタミンD誘導体の創製2016
- Author(s)
  影近弘之、藤井晋也、増野弘幸、平野智也、棚谷綾
- Organizer
  第２回Neo VitaminD Workshop学術集会
- Place of Presentation
  TKP品川カンファレンスセンター（東京都・港区）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-16K15138
[Presentation] Design and synthesis of novel ROR inverse agonists based on silicon-containing hetgerocyclic core structure2015
- Author(s)
  H. Toyama, M. Nakamura, Y. Hashimoto, S. Fujii
- Organizer
  PACIFICHEM 2015 (2015 International Chemical Congress of Pacific Basin Societies)
- Place of Presentation
  Honolulu, Hawaii (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] 三次元分子構築と元素化学的アプローチを基盤とした疎水性ファーマコフォアの開発2015
- Author(s)
  藤井晋也
- Organizer
  第５９回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県・船橋市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] Development of androgen receptor (AR) activation function-1 (AF-1) modulators2015
- Author(s)
  Shinya Fujii, Akiyoshi Numadate, Tomomi Noguchi-Yachide, Kaori Endo-Umeda, Makoto Makishima, and Yuichi Hashimoto
- Organizer
  The 3rd International Conference on Retinoids
- Place of Presentation
  岐阜グランドホテル（岐阜県岐阜市）
- Year and Date
  2015-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] アンドロゲン受容体AF-1モジュレーターの創製2015
- Author(s)
  沼館慧剛，谷内出友美，梅田香織，槇島誠，橋本祐一，藤井晋也
- Organizer
  日本ケミカルバイオロジー学会第１０回年会
- Place of Presentation
  東北大学（宮城県・仙台市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] Development of novel nuclear receptor modulators based on silyl functionality as hydrophobic core structure2015
- Author(s)
  Fujii, S.; Miyajima, Y.; Toyama, H.; Kajita, D.; Nakamura, M.; Kagechika, H.; Hashimoto, Y.
- Organizer
  ASMC2015
- Place of Presentation
  Rehovot, Israel
- Year and Date
  2015-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] フェナンスリジノン骨格を有するステロイドホルモン受容体リガンドの創製2015
- Author(s)
  西山郵子、藤井晋也、石川稔、橋本祐一、槇島誠
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研究センター（千葉県千葉市）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] 含ケイ素複素環を骨格構造とする新規ROR転写抑制リガンドの創製2015
- Author(s)
  外山大純，中村雅陽，橋本祐一，藤井晋也
- Organizer
  日本ケミカルバイオロジー学会第１０回年会
- Place of Presentation
  東北大学（宮城県・仙台市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] Development of silicon-based biological active compounds by focusing on silyl functionality as a cis-olefin mimetic2015
- Author(s)
  D. Kajita, M. Nakamura, Y. Matsumoto, M. Ishikawa, Y. Hashimoto, S. Fujii
- Organizer
  PACIFICHEM 2015 (2015 International Chemical Congress of Pacific Basin Societies)
- Place of Presentation
  Honolulu, Hawaii (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] Polypharmacological profiles of phenathridinone derivatives2015
- Author(s)
  Y. Nishiyama, T. Misawa, H. Aoyama, S. Fujii, M. Ishikawa, Y. Hashimoto
- Organizer
  PACIFICHEM 2015 (2015 International Chemical Congress of Pacific Basin Societies)
- Place of Presentation
  Honolulu, Hawaii (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] Development of androgen receptor (AR) activation function-1 (AF-1) modulators2015
- Author(s)
  Fujii, S.; Numadate, A.; Noguchi-Yachide, T.; Endo-Umeda, K.; Makishima, M.; Hashimoto, Y.
- Organizer
  3rd International Conference on Retinoids.
- Place of Presentation
  岐阜グランドホテル（岐阜県・岐阜市）
- Year and Date
  2015-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] 新規疎水性ファーマコフォアを有するビタミンD受容体リガンドの創製2015
- Author(s)
  藤井晋也，平野智也，棚谷綾，影近弘之
- Organizer
  第１回Neo Vitamin D Workshop学術集会
- Place of Presentation
  大津プリンスホテル（滋賀県・大津市）
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] メナキノン酸化誘導体の系統的合成と抗炎症作用2015
- Author(s)
  藤井晋也，清水章貴，小口一起，桂井朋子，白川仁，駒井三千夫，影近弘之
- Organizer
  日本ビタミン学会第６７回大会
- Place of Presentation
  奈良県新公会堂（奈良県・奈良市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] クマリン骨格を基盤とした新規アンドロゲン受容体アンタゴニストの創製2014
- Author(s)
  古賀瞳，木下満里絵，藤井晋也，影近弘之，棚谷綾
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] カルボランを基盤とした新規ビタミンＤ誘導体の創製2014
- Author(s)
  八田健司，河内恵美子，増野弘幸，藤井晋也，影近弘之
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] カルボランを基盤とした新規ビタミンＤ誘導体の創製2014
- Author(s)
  八田健司、河内恵美子、増野弘幸、藤井晋也、影近弘之
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] カルボランを基盤とした新規ビタミンD誘導体の創製2014
- Author(s)
  八田健司, 河内恵美子, 増野弘幸, 藤井晋也, 影近弘之
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] クマリン骨格を基盤とした新規アンドロゲン受容体アンタゴニストの創製2014
- Author(s)
  古賀瞳、木下満里絵、藤井晋也、影近弘之、棚谷綾
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] クマリン骨格を基盤とした新規アンドロゲン受容体アンタゴニストの創製2014
- Author(s)
  古賀瞳、木下満里絵、藤井晋也、影近弘之、棚谷綾
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] クマリン骨格を基盤とした新規アンドロゲン受容体アンタゴニストの創製2014
- Author(s)
  古賀瞳, 木下満里絵, 藤井晋也, 影近弘之, 棚谷綾
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] カルボランを基盤とした新規ビタミンＤ誘導体の創製2014
- Author(s)
  八田健司、河内恵美子、増野弘幸、藤井晋也、影近弘之
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Increased hydrophobicity and estrogenic activity of silicon- and germanium-containing phenols2013
- Author(s)
  Fujii, S.; Miyajima, Y.; Masuno, H.; Kagechika, H.
- Organizer
  14th Tetrahedron Symposium
- Place of Presentation
  ウィーン、オーストリア
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] 新規ファーマコフォアの構築に基づくアンドロゲン受容体パンアンタゴニストの創製2013
- Author(s)
  藤井晋也，山田歩，森修一，影近弘之
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] 球状疎水性ファーマコフォアを有する非セコステロイド型ＶＤＲリガンドの構造活性相関2013
- Author(s)
  藤井晋也、Angsuma Wongmayura、増野弘幸、伊藤茂、加納敦、河内恵美子、棚谷綾、影近弘之
- Organizer
  日本ビタミン学会第65回大会
- Place of Presentation
  一橋講堂（東京）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Development of Novel Estrogen Receptor Agonists Based on Silicon- and Germanium-Containing Hydrophobic Functionalities2013
- Author(s)
  Masuno, H., Miyajima, Y., Fujii, S., Kagechika, H
- Organizer
  The 2nd HD Physiology International Symposium on Multi-Level Systems Biology
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] 疎水性球状分子を骨格とする新規プロゲステロン受容体アンタゴニストの創製2013
- Author(s)
  森修一, 竹内由起, 中野英一, 藤井晋也, 棚谷綾, 影近弘之
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] 疎水性球状分子を骨格とする新規プロゲステロン受容体アンタゴニストの創製2013
- Author(s)
  森修一、竹内由起、中野英一、藤井晋也、棚谷綾、影近弘之
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ（広島）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] 球状疎水性ファーマコフォアを有する非セコステロイド型ＶＤＲリガンドの構造活性相関2013
- Author(s)
  藤井晋也、Angsuma Wongmayura、増野弘幸、伊藤茂、加納敦、河内恵美子、棚谷綾、影近弘之
- Organizer
  日本ビタミン学会第65回大会
- Place of Presentation
  一橋講堂（東京）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Increased hydrophobicity and estrogenic activity of silicon- and germanium-containing phenols2013
- Author(s)
  Shinya Fujii, Yu Miyajima, Hiroyuki Masuno, Hiroyuki Kagechika
- Organizer
  14th Tetrahedron Symposium
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] 新規ファーマコフォアの構築に基づくアンドロゲン受容体パ;ンアンタゴニストの創製2013
- Author(s)
  藤井晋也、山田歩、森修一、影近弘之
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京医科歯科大学（東京）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] クルクミンの構造要素を基盤とした新規アンドロゲン受容体アンタゴニストの創製2013
- Author(s)
  藤井晋也、山田歩、森修一、影近弘之
- Organizer
  第２４回日本レチノイド研究会学術集会
- Place of Presentation
  星薬科大学（東京）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] シリル基・ゲルミル基の疎水性基としての性質と新規エストロゲン受容体リガンド創製への応用2013
- Author(s)
  藤井晋也
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] クルクミンの構造要素を基盤とした新規ARアンタゴニストの創製2013
- Author(s)
  藤井晋也，山田歩，森修一，影近弘之
- Organizer
  第24回日本レチノイド研究会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] クルクミンの構造要素を基盤とした新規アンドロゲン受容体アンタゴニストの創製2013
- Author(s)
  藤井晋也、山田歩、森修一、影近弘之
- Organizer
  第２４回日本レチノイド研究会学術集会
- Place of Presentation
  星薬科大学（東京）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] 球状疎水性ファーマコフォアを有する非セコステロイド型ＶＤＲリガンドの構造活性相関2013
- Author(s)
  藤井晋也，Angsuma Wongmayura，増野弘幸，伊藤茂，加納敦，河内恵美子，棚谷綾，影近弘之
- Organizer
  日本ビタミン学会第６５回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] 球状疎水性ファーマコフォアを有する非セコステロイド型VDRリガンドの構造活性相関2013
- Author(s)
  藤井晋也, Angsuma Wongmayura, 増野弘幸, 伊藤茂, 加納敦, 河内恵美子, 棚谷綾, 影近弘之
- Organizer
  日本ビタミン学会第65回大会
- Place of Presentation
  東京
- Year and Date
  2013-05-17
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] クルクミンの構造要素を基盤とした新規アンドロゲン受容体アンタゴニストの創製2013
- Author(s)
  藤井晋也, 山田歩, 森修一, 影近弘之
- Organizer
  第24回日本レチノイド研究会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] シリル基・ゲルミル基の疎水性基としての性質と新規エストロゲン受容体リガンド創製への応用2013
- Author(s)
  藤井晋也,宮島友,増野弘幸,影近弘之.
- Organizer
  日本薬学会133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of novel estrogen receptor agonists based on　silicon- and germanium-containing hydrophobic functionalities2013
- Author(s)
  Masuno, H.; Miyajima, Y.; Fujii, S.; Kagechika, H.
- Organizer
  The 2st HD Physiology International Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] Development of Novel Estrogen Receptor Agonists Based on Silicon- and Germanium-Containing Hydrophobic Functionalities2013
- Author(s)
  Hiroyuki Masuno, Yu Miyajima, Shinya Fujii, Hiroyuki Kagechika
- Organizer
  2nd HDP international symposium on Multi-Level Systems Biology
- Place of Presentation
  MARUNOUCHI MY PLAZA HALL（東京）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] シリル基・ゲルミル基の疎水性基としての性質と新規エストロゲン受容体リガンド創製への応用2013
- Author(s)
  藤井晋也
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] アンドロゲン受容体アンタゴニスト活性を有する新規フェノキシフェノール誘導体の構造活性相関2013
- Author(s)
  数井優子, 山田歩, 藤井晋也, 影近弘之, 棚谷綾
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Development of Novel Estrogen Receptor Agonists Based on Silicon- and Germanium-Containing Hydrophobic Functionalities2013
- Author(s)
  Hiroyuki Masuno, Yu Miyajima, Shinya Fujii, Hiroyuki Kagechika
- Organizer
  2nd HDP international symposium on Multi-Level Systems Biology
- Place of Presentation
  MARUNOUCHI MY PLAZA HALL（東京）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] アンドロゲン受容体アンタゴニスト活性を有する新規フェノキシフェノール誘導体の構造活性相関2013
- Author(s)
  数井優子、山田歩、藤井晋也、影近弘之、棚谷綾
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ（広島）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] ビタミンK 酸化誘導体の系統的合成とその生理活性2013
- Author(s)
  清水章貴, 藤井晋也, 影近弘之
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] アンドロゲン受容体アンタゴニスト活性を有する新規フェノキシフェノール誘導体の構造活性相関2013
- Author(s)
  数井優子、山田歩、藤井晋也、影近弘之、棚谷綾
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ（広島）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] 疎水性球状分子を骨格とする新規プロゲステロン受容体アンタゴニストの創製2013
- Author(s)
  森修一、竹内由起、中野英一、藤井晋也、棚谷綾、影近弘之
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ（広島）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] 新規ファーマコフォアの構築に基づくアンドロゲン受容体パンアンタゴニストの創製2013
- Author(s)
  藤井晋也, 山田歩, 森修一, 影近弘之
- Organizer
  ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] 新規ファーマコフォアの構築に基づくアンドロゲン受容体パンアンタゴニストの創製2013
- Author(s)
  藤井晋也、山田歩、森修一、影近弘之
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京医科歯科大学（東京）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] ホウ素クラスターを基盤としたビタミンD の構造展開2013
- Author(s)
  影近弘之,藤井晋也,増野弘幸
- Organizer
  第341回脂溶性ビタミン総合研究委員会
- Place of Presentation
  奈良
- Year and Date
  2013-12-06
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Synthesis and characterization of a conjugated macrocyclic compound containing a carborane cage2013
- Author(s)
  Iihama, S.; Fujii, S.; Kagechika, H.
- Organizer
  14th Tetrahedron Symposium
- Place of Presentation
  ウィーン、オーストリア
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] Increased hydrophobicity and estrogenic activity of silicon- and germanium-containing phenols2013
- Author(s)
  Fujii, S., Miyajima, Y., Masuno, H., Kagechika, H
- Organizer
  14th Tetrahedron Symposium
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Development of Nuclear Receptor Ligands Based on Carborane as Hydrophobic Core Structure2012
- Author(s)
  Fujii, S.; Yamada, A.; Ohta, K.; Endo, Y.; Kagechika, H.
- Organizer
  The 1st HD Physiology International Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] シリル基・ゲルミル基の疎水性基としての性質と新規エストロゲン受容体リガンドの創製2012
- Author(s)
  藤井晋也,宮島友,増野弘幸,影近弘之.
- Organizer
  日本レチノイド研究会第23回学術集会
- Place of Presentation
  米子
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] シリル基・ゲルミル基の疎水性基としての性質と新規エストロゲン受容体リガンドの創製2012
- Author(s)
  藤井晋也
- Organizer
  第23回日本レチノイド研究会学術集会
- Place of Presentation
  米子
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Structure-activity relationship and structural basis of carborane-based VDR ligands2012
- Author(s)
  Shinya Fujii
- Organizer
  Molecular Chirality Asia 2012
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] トリアジン構造を基盤とした新規NF-κB阻害剤の創製2012
- Author(s)
  中津　亜紀, 藤井　晋也, 小林　隆信, 宮澤　宏, 影近　弘之
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of Nuclear Receptor Ligands Based on Carborane as Hydrophobic Core Structure2012
- Author(s)
  Fujii, S.
- Organizer
  The 1st HD Physiology International Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Hydrophobic parameters, substituent constants and estrogenic activities of silyl- and germyl-containing phenols2012
- Author(s)
  Fujii, S.; Miyajima, Y.; Masuno, H.; Kagechika, H.
- Organizer
  ISMC2012 International Symposium of Medicinal Chemistry 2012
- Place of Presentation
  ベルリン(ドイツ).
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] カルボランアニオンの炭素頂点におけるクロスカップリング反応の開発2012
- Author(s)
  金澤　純一朗，滝田　良，藤井　晋也，影近　弘之，内山　真伸
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Hydrophobic parameters, substituent constants and estrogenic activities of silyl- and germylcontaining phenols2012
- Author(s)
  Fujii, S.
- Organizer
  Int Symp Med Chem 2012 (ISMC2012)
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] クルクミンの構造要素を基盤とした新規ARアンタゴニストの創製2012
- Author(s)
  山田　歩、藤井　晋也、影近　弘之
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Hydrophobic parameters, substituent constants and estrogenic activities of silyl- and germiyl-containing phenols2012
- Author(s)
  Shinya Fujii
- Organizer
  ISMC2012
- Place of Presentation
  ベルリン（ドイツ）
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of Nuclear Receptor Ligands Based on Carborane as Hydrophobic Core Structure.2012
- Author(s)
  Shinya Fujii, Ayumi Yamada Kiminori Ohta, Yasuyuki Endo, Hiroyuki Kagechika
- Organizer
  The 1st HD Physiology International Symposium
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Hydrophobic parameters, substituent constants and estrogenic activities of silyl- and germyl-containing phenols2012
- Author(s)
  Fujii, S., Miyajima, Y., Masuno, H., Kagechika, H
- Organizer
  Int Symp Med Chem
- Place of Presentation
  Berlin
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] トリアルキルシリルおよびゲルミル基の性質と生理活性物質の疎水性構造への応用2012
- Author(s)
  藤井晋也
- Organizer
  日本ケミカルバイオロジー学会第７回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Development of Fluorescent Ligands for Nuclear Hormone Receptor.2012
- Author(s)
  Tomoya Hirano, Haruka Sakai, Shuichi Mori, Shinya Fujii, Hiroyuki Masuno, Marie Kinoshita, Aya Tanatani, Hiroyuki Kagechika
- Organizer
  The 1st HD Physiology International Symposium
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] シリル基・ゲルミル基の疎水性基としての性質と新規エストロゲン受容体リガンドの創製2012
- Author(s)
  藤井晋也
- Organizer
  日本レチノイド研究会第24回学術集会
- Place of Presentation
  米子
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] クルクミンの構造要素を基盤とした新規AR アンタゴニストの創製2012
- Author(s)
  山田歩, 藤井晋也, 影近弘之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Development of Various Functional Molecules Based on Hydrophobic and Fluorescent Scaffolds2012
- Author(s)
  Hirano, T., Fujii, S., Mori, S., Tanatani, A., Kagechika, H
- Organizer
  The 1st Official Conference of the International Chemical Biology Society (ICBS2012)
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] トリアルキルシリルおよびゲルミル基の性質と生理活性物質の疎水性構造への応用2012
- Author(s)
  藤井晋也, 宮島友, 増野弘幸, 影近弘之
- Organizer
  ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] 球状の脂溶性ファーマコフォアを有するビタミンD誘導体の創製2012
- Author(s)
  Angsuma WONGMAYURA，藤井　晋也，伊藤　茂，河内　恵美子，影近　弘之，棚谷　綾
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] 変異アンドロゲン受容体(AR) にも有効な新規カルボラン含有AR アンタゴニストの創製2012
- Author(s)
  皆瀬　麻子，後藤　徳仁，藤井　晋也，太田　公規，遠藤　泰之
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of novel RXR ligands bearing tralkylsilyl or trialkylgermyl groups2012
- Author(s)
  Masuno, H., Fujii, S., Kawach, E., Kagechika, H
- Organizer
  The 1st HD Physiology International Symposium: Integrative Multi-level Systems
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] カルボラン含有ＶＤＲリガンドの構造活性相関と結合様式2012
- Author(s)
  藤井晋也
- Organizer
  Molecular Chirality 2012
- Place of Presentation
  福岡
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] トリアルキルシリルおよびゲルミル基の性質と生理活性物質の疎水性構造への応用2012
- Author(s)
  藤井晋也
- Organizer
  日本ケミカルバイオロジー学会第７回年会
- Place of Presentation
  京都
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] トリアジン構造を基盤としたＮＦκＢ－ＤＮＡ結合阻害剤の創製2012
- Author(s)
  藤井晋也
- Organizer
  ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of Nuclear Receptor Ligands Based on Carborane as Hydrophobic Core Structure2012
- Author(s)
  Fujii, S., Yamada, A., Ohta, K., Endo, Y., Kagechika, H
- Organizer
  The 1st HD Physiology International Symposium: Integrative Multi-level Systems
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] トリアルキルシリルおよびゲルミル基の性質と生理活性物質の疎水性構造への応用2012
- Author(s)
  藤井晋也
- Organizer
  ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Hydrophobic parameters, substituent constants and estrogenic activities of silyl- and germyl-containing phenols2012
- Author(s)
  Fujii, S.
- Organizer
  Int Symp Med Chem 2012 (ISMC2012)
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-09-02
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] トリアルキルシリルおよびゲルミル基の性質と生理活性物質の疎水性構造への応用2012
- Author(s)
  藤井晋也,宮島友,増野弘幸,影近弘之.
- Organizer
  日本ケミカルバイオロジー研究会第7回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Design and Synthesis of Novel VDR Ligand having A Spherical Hydrophobic Structure2012
- Author(s)
  Masuno, H., Fujii, S., Wongmayura, A., Ito, S., Kawachi, E., Tanatani, A., Kagechika, H
- Organizer
  Vitamin D Workshop
- Place of Presentation
  Houston, USA
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] 変異アンドロゲン受容体(AR)にも有効な新規カルボラン含有ARアンタゴニストの創製2012
- Author(s)
  皆瀬麻子、後藤徳仁、藤井晋也、太田公規、遠藤泰之
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] Design and Synthesis of Novel AR Antagonists having a glycerol moiety2011
- Author(s)
  Asako Kaise, Tokuhito Goto, Shinya Fujii , Kiminori Ohta, Yasuyuki Endo
- Organizer
  IME Boron XIV
- Place of Presentation
  Niagara falls, Canada
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] カルボランを基盤とした新規非ステロイド型PRリガンドの創製2011
- Author(s)
  中野英一, 藤井晋也, 森修一, 柳田尚毅, 影近弘之
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] Development of Novel Progesterone Receptor Antagonists Based on Boron Cluster as a Hydrophobic Core Structure2011
- Author(s)
  Eiichi Nakano, Naoki Yanagida, Shuichi Mori, Shinya Fujii, Hiroyuki Kagechika
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] カルボランを基盤とした新規非セコステロイド型ビタミンD受容体リガンドの創製2011
- Author(s)
  関根良太、藤井晋也、増野弘幸、加納敦、中林誠、伊藤暢聡、河内恵美子、棚谷綾、平野智也、影近弘之
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] Development of Novel AR Antagonists Active in LNCaP Cells with Mutated Androgen Receptor.2011
- Author(s)
  Yamada, A., Fujii, F., Tomita, K., Nagano, M., Harayama, T., Ohta, K., Endo, Y., Kagechika, H.
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of novel carborane-based androgen receptor antagonists effective to mutated receptor.2011
- Author(s)
  Yamada, A.; Fujii, S.; Tomita, K.; Nagano, M.; Harayama, T.; Ohta, K.; Endo, Y.; Kagechika, H.
- Organizer
  IME Boron XIV
- Place of Presentation
  Niagara Falls, Canada
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of Nuclear Receptor Ligands Based on Carborane as Hydrophobic Core Structure2011
- Author(s)
  Fujii, S.
- Organizer
  The 1st HD Physiology International Symposium
- Place of Presentation
  東京
- Year and Date
  2011-01-19
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Development of Silicon- and Germanium-containing Ligands for Nuclear Receptors.2011
- Author(s)
  Masuno, H., Fujii, S., Miyajima, Y., Kawachi, E., Kagechika, H.
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development and Structural Basis of Novel Non-secosteroidal VDR Ligands Based on Hydrophobic Carborane Cage2011
- Author(s)
  Fujii, S.
- Organizer
  IME Boron XIV
- Place of Presentation
  Niagara Falls, Canada
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] フタラジノン骨格を有する新規アンドロゲン受容体アンタゴニストの創製2011
- Author(s)
  井上和美, 藤井晋也, 森修一, 影近弘之, 棚谷綾
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] Design and synthesis of novel carborane-containing AR antagonists having a grycerol moiety based on the co-crystal structure of bicalutamide with hAR LBD.2011
- Author(s)
  Kaise, A., Goto, T., Fujii, S., Ohta, K., Endo, Y.
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] N,N’-ジアリールスクアルアミドの立体特性2011
- Author(s)
  神田翠，藤井晋也，片桐幸輔，桝飛雄真，東屋功，影近弘之，棚谷綾．
- Organizer
  第36回反応と合成の進歩シンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] ケイ素およびゲルマニウムを持つレチノイドX受容体リガンドの開発2011
- Author(s)
  増野弘幸，藤井晋也，前田満将，前田貴志，平野智也，河内恵美子，影近弘之
- Organizer
  日本ビタミン学会第63回大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development and Structural Basis of Novel Non-secosteroidal VDR Ligands Based on Hydrophobic Carborane Cage2011
- Author(s)
  Fujii, S.
- Organizer
  IME Boron XIV
- Place of Presentation
  Niagara Falls, Canada
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Design and synthesis of novel AR antagonists having a grycerol moiety.2011
- Author(s)
  Kaise, A.; Goto, T.; Fujii, S.; Ohta, K.; Endo, Y.
- Organizer
  IME Boron XIV
- Place of Presentation
  Niagara Falls, Canada
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] 共結晶構造を基にした効果的な抗アンドロゲン化合物の創製2011
- Author(s)
  皆瀬麻子, 後藤徳仁, 藤井晋也, 太田公規遠藤泰之
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] Development and structural basis of novel non-secosteroidal VDR ligands based on hydrophobic carborane cage2011
- Author(s)
  Fujii, S.; Masuno, H.; Nakabayashi, M.; Hirano, T.; Kawachi, E.; Ito, N.; Kagechika, H.
- Organizer
  IME Boron XIV 14th International Meeting on Boron Chemistry
- Place of Presentation
  ナイアガラフォールズ(カナダ)
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] ケイ素およびゲルマニウムを持つレチノイドX 受容体(RXR)リガンドの開発2011
- Author(s)
  増野弘幸, 藤井晋也, 前田満将, 前田貴志, 平野智也, 河内恵美子, 影近弘之
- Organizer
  ビタミン学会第63回大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Efficient and Diversity-Oriented Total Synthesis of Riccardin C2011
- Author(s)
  Fujii S.
- Organizer
  AIMECS
- Place of Presentation
  東京
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Development and structural basis of novel non-secosteroidal VDR ligands based on hydrophobic carborane cage2011
- Author(s)
  Fujii, S., Masuno, H., Nakabayashi, M., Hirano, T., Kawachi, E., Ito, N., Kagechika, H
- Organizer
  IME Boron XIV
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Development of Novel AR Antagonists Active in LNCaP Cells with Mutated Androgen Receptor2011
- Author(s)
  Yamada, A., Fujii, S., Tomita, K., Nagano, M., Harayama, T., Ohta, K., Endo, Y., Kagechika, H
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Efficient and Diversity-Oriented Total Synthesis of Riccardin C.2011
- Author(s)
  Shinya Fujii, Masazumi Iwashita, Shigeru Ito, Tomoya Hirano, Hiroyuki Kagechika
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of novel carborane-based androgen receptor antagonists effective for mutated receptor2011
- Author(s)
  Yamada, A., Fujii, S., Tomita, K., Nagano, M., Harayama, T., Ohta, K., Endo, Y., Kagechika, H
- Organizer
  IME Boron XIV
- Place of Presentation
  Niagara Falls, Canada
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Novel non-secosteroidal vitamin D receptor ligands bearing a spherical hydrophobic core. - Difference between carborane and bicyclohydrocarbon -2011
- Author(s)
  Angsuma, W.; Fujii, S.; Sekine, R.; Kano, A.; Kawachi, E.; Masuno, H.; Hirano, T.; Kagechika, H.; Tanatani, A.
- Organizer
  IME Boron XIV
- Place of Presentation
  Niagara Falls, Canada
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Development of Siliconand Germanium-containing Ligands for Nuclear Receptors2011
- Author(s)
  Masuno, H., Fujii, S., Miyajima, Y., Kawachi, E., Kagechika, H
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Development and structural basis of novel non-secosteroidal VDR ligands based on hydrophobic carborane cage.2011
- Author(s)
  Fujii, S.; Masuno, H.; Nakabayashi, M.; Hirano, T.; Kawachi, E.; Ito, N.; Kagechika, H.
- Organizer
  IME Boron XIV
- Place of Presentation
  Niagara Falls, Canada
- Data Source
  KAKENHI-PROJECT-23790128
[Presentation] Design and Synthesis of Novel Carboranecontaining AR Antagonists Having a Glycerol Moiety Based on the Co-crystal Structure of Bicalutamide with hAR LBD2011
- Author(s)
  Asako Kaise, Tokuhito Goto, Shinya Fujii , Kiminori Ohta, Yasuyuki Endo
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] ケイ素およびゲルマニウム含有フェノール誘導体の性質と生物活性2011
- Author(s)
  宮島友, 藤井晋也, 増野弘幸, 影近弘之
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] カルボランを疎水性骨格とする新規アンドロゲン受容体リガンドの創製2010
- Author(s)
  藤井晋也
- Organizer
  第7回中性子捕獲療法学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] 変異受容体にも有効な新規アンドロゲンアンタゴニストの創製2010
- Author(s)
  山田歩、冨田景子、長野也麻央、藤井晋、原山尚、太田公規、遠藤泰之、影近弘之
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] カルボランを基盤としたチオエーテル構造を有する新規VDRリガンドの創製2010
- Author(s)
  関根良太、藤井晋也、増野弘幸、平野智也、河内恵美子、棚谷綾、影近弘之
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] Development of novel nonsteroidal androgen receptor ligands based on hydrophobic boron clusters2010
- Author(s)
  Shinya Fujii, Kiminori Ohta, Yasuyuki Endo, Hiroyuki Kagechika
- Organizer
  ICE2010 Official Satellite Symposia 'Nuclear Receptor and its Frontier'
- Place of Presentation
  京都
- Year and Date
  2010-03-31
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] ビタミンD活性を有するリトコール酸誘導体の創製2010
- Author(s)
  数井優子、増野弘幸、藤井晋也、平野智也、河内恵美子、影近弘之、棚谷綾
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] 変異ARを有するLNCaP細胞に対して有効な新規ARアンタゴニストの創製2010
- Author(s)
  山田歩, 富田景子, 長野麻央, 藤井晋也, 原山尚, 太田公規, 遠藤泰之, 影近弘之
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  慶応義塾大学日吉キャンパス横浜(神奈川)
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] 変異受容体にも有効な新規アンドロゲンアンタゴニストの創製2010
- Author(s)
  山田歩, 富田景子, 長野麻央, 藤井晋也, 原山尚, 太田公規, 遠藤泰之, 影近弘之
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] VDR活性をもつLCA誘導体の合成とVDR結合構造の解析2010
- Author(s)
  増野弘幸, 数井優子, 伊倉貞吉, 中林誠, 伊藤暢聡, 藤井晋也, 河内恵美子, 棚谷綾, 影近弘之
- Organizer
  日本ビタミン学会第62回大会
- Place of Presentation
  岩手県民情報交流センター盛岡(岩手)
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] カルボランを疎水性骨格とする新規アンドロゲン受容体リガンドの創製2010
- Author(s)
  藤井晋也, 山田歩, 太田公規, 遠藤泰之, 影近弘之
- Organizer
  第7回日本中性子捕捉療法学会学術集会
- Place of Presentation
  学習院大学豊島区(東京)
- Year and Date
  2010-08-05
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] Development of novel androgen antagonists based on hydrophobic boron clusters.2010
- Author(s)
 Fujii S., Yamada A., Ohta K., Endo Y., Kagechika H.
- Organizer
 EFMC-ISMC 2010 : 21^<st> International symposium on medicinal chemistry
- Place of Presentation
 SQUARE ブリュッセル(ベルギー)
- Year and Date
 2010-09-08
- Data Source
 KAKENHI-PROJECT-21790110
[Presentation] ホウ素クラスターを疎水性骨格とする新規非セコステロイド型ビタミンD誘導体:受容体結合様式と構造展開2010
- Author(s)
  藤井晋也
- Organizer
  日本レチノイド研究会第21回学術集会
- Place of Presentation
  高槻(大阪)
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Development of Novel Androgen Antagonists Based on Hydrophobic Boron Clusters2010
- Author(s)
  Fujii, S.
- Organizer
  International Symposium on Medicinal Chemistry
- Place of Presentation
  Brussels, Bergium
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Development of novel androgen antagonists based on hydrophobic boron clusters2010
- Author(s)
 Shinya Fujii, Ayumi Yamada, Kiminori Ohta, Yasuyuki Endo, Hiroyuki Kagechika
- Organizer
 EFMC-ISMC 2010 : 21^<st> International symposium on medicinal chemistry
- Place of Presentation
 ブリュッセル(ベルギー)
- Year and Date
 2010-09-08
- Data Source
 KAKENHI-PROJECT-21790110
[Presentation] ホウ素クラスターを疎水性骨格とする新規非セコステロイド型ビタミンD誘導体-受容体結合様式と構造展開-2010
- Author(s)
  藤井晋也, 増野弘幸, 垰田善之, 加納敦, 中林誠, 伊藤暢聡, 河内恵美子, 清水正人, 棚谷綾, 平野智也, 影近弘之
- Organizer
  日本レチノイド研究会第21回学術集会
- Place of Presentation
  大阪医科大学高槻市(大阪)
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] VDR活性をもつLCA誘導体の合成とVDR結合構造の解析2010
- Author(s)
  増野弘幸、数井優子、伊倉貞吉、中林誠、伊藤暢聡、藤井晋也、河内恵美子、棚谷綾、影近弘之
- Organizer
  日本ビタミン学会第62回大会
- Place of Presentation
  盛岡
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] ホウ素クラスターを疎水性骨格とする新規非セコステロイド型ビタミンD誘導体-受容体結合様式と構造展開-2010
- Author(s)
  藤井晋也、増野弘幸、垰田善之、加納敦、中林誠、伊藤暢聡、河内恵美子、清水正人、棚谷綾、平野智也、影近弘之
- Organizer
  日本レチノイド研究会第21回学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] 6-アリールクマリン環を母核とした新規プロゲステロンアンタゴニストの創製2010
- Author(s)
  酒井悠, 平野智也, 森修一, 藤井晋也, 影近弘之, 棚谷綾
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] 10-vertexカルボランを用いたアンドロゲン受容体リガンドの創製2009
- Author(s)
  藤井晋也
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] 10-vertex カルボランを用いたアンドロゲン受容体リガンドの創製2009
- Author(s)
  藤井晋也、太田公規、遠藤泰之、影近弘之
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] カルボランを疎水性骨格とする新規非ステロイド型VDRリガンドの構造展開2009
- Author(s)
  藤井晋也、加納敦、平野智也、河内恵美子、増野弘幸、棚谷綾、中林誠、伊倉貞吉、伊藤暢聡、清水正人、影近弘之
- Organizer
  第35回反応と合成の進歩シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] Structures of Non-secosteroid Ligands Bound to Vitamin D Nuclear Receptor2009
- Author(s)
  Hiroyuki Masuno, Shinya Fujii, Makoto Nakabayashi, Teikichi Ikura, Nobutoshi Ito, Masato Shimizu, Hiroyuki Kagechika
- Organizer
  14th Workshop on Vitamin D
- Place of Presentation
  ブルージュ(ベルギー)
- Year and Date
  2009-10-07
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] カルボランを疎水性骨格とする新規核内受容体リガンドの創製2009
- Author(s)
  藤井晋也, 太田公規, 遠藤泰之, 影近弘之
- Organizer
  第120回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] 変異を有するARに対して有効な新規ARアンタゴニストの創製2009
- Author(s)
  藤井晋也、山田歩、富田景子、長野麻央、原山尚、太田公規、遠藤泰之、影近弘之
- Organizer
  日本レチノイド研究会第20回学術集会
- Place of Presentation
  東京
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] 新規非セコステロイド型VDRリガンドの構造展開と受容体結合様式の解析2009
- Author(s)
  藤井晋也、加納敦、平野智也、河内恵美子、増野弘幸、棚谷綾、中林誠、伊倉貞吉、伊藤暢聡、清水正人、影近弘之
- Organizer
  日本ビタミン学会第61回大会
- Place of Presentation
  京都
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] Development of novel non-secosteroidal vitamin D receptor ligands based on carborane as a hydrophobic core structure2009
- Author(s)
  Shinya Fujii, Atsushi Kano, Ryota Sekine, Emiko Kawachi, Hiroyuki Masuno, Tomoya Hirano, Aya Tanatani, Hiroyuki Kagechika
- Organizer
  14th Workshop on Vitamin D
- Place of Presentation
  ブルージュ(ベルギー)
- Year and Date
  2009-10-05
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] 変異ARに対して有効なカルボラン含有新規ARアンタゴニストの創製2009
- Author(s)
  山田歩, 富田景子, 長野麻央, 藤井晋也, 原山尚, 太田公規, 遠藤泰之, 影近弘之
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-21790110
[Presentation] カルボラン骨格を利用したアンドロゲン受容体変異に対しても有効な拮抗剤の創製2008
- Author(s)
  太田公規、後藤徳仁、藤井晋也、鈴木智晴、太田茂、遠藤泰之
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] Utility of boron cluster for drug design:Design of androgen receptor/ estrogen receptor dual ligands bearing carborane for anti-prostate cancer drug2008
- Author(s)
  Yasuyuki Endo , Tokuhito Goto, Kiminori Ohta, Shinya Fujii, Hiroyuki Kagechika
- Organizer
  13th International Conferenceon Boron Chemistry
- Place of Presentation
  Platja d'Aro, Spain
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] Androgen receptor antagonists based on boron cluster as a hydrophobic core structure2008
- Author(s)
  Shinya Fujii, Kiminori Ohta, Tokuhito Goto, Tomoharu Suzuki, Shigeru Ohta, Yuichi Hashimoto, Hiroyuki Kagechika, Yasuyuki Endo
- Organizer
  13th International Conference on Boron Chemistry
- Place of Presentation
  Platja d'Aro, Spain
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] Diarylcarborane 構造を利用したエストロゲン活性および抗アンドロゲン活性を併せ持つ化合物の創製2008
- Author(s)
  太田公規,後藤徳仁,小川卓巳,藤井晋也,鈴木智晴,太田茂,遠藤泰之
- Organizer
  第19回日本レチノイド研究会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390035
[Presentation] アミド構造を有する含カルボランARリガンドの構造活性相関2007
- Author(s)
  藤井晋也, 後藤徳仁, 太田公規, 富田景子, 長野麻央, 原山尚, 影近弘之, 遠藤泰之
- Organizer
  第26回メディシナルケミストリーシンポジウム
- Place of Presentation
  相模原
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-18790094
[Presentation] カルボラン含有新規ビタミンD誘導体の創製2007
- Author(s)
  加納敦, 垰田善之, 平野智也, 藤井晋也, 河内恵美子, 棚谷綾, 影近弘之
- Organizer
  第26回メディシナルケミストリーシンポジウム
- Place of Presentation
  相模原
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-18790094
[Presentation] Potent androgen antagonists based on carborane as a hydrophobic core structure2007
- Author(s)
  Fujii, S., Ohta, K., Goto, T., Hashimoto, Y., Suzuki, T., Ohta, S., Endo, Y.
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-18790094
[Presentation] Lipase-catalyzed asymmetric acylation of boron cluster-containing secondary alcohols
- Author(s)
  Shuichi Mori, Ryohei Takagaki, Shinya Fujii, Mio Matsumura, Aya Tanatani, and Hiroyuki Kagechika
- Organizer
  Active Enzyme Molecule 2014
- Place of Presentation
  富山
- Year and Date
  2014-12-17 – 2014-12-19
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] アンドロゲン受容体アンタゴニスト活性を有する新規シラノール誘導体の創製
- Author(s)
  山内夢人、藤井晋也、増野弘幸、河内恵美子、影近弘之
- Organizer
  第３２回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] 高血圧治療薬開発を志向したWNKシグナル阻害剤の創薬
- Author(s)
  鈴山帆乃佳、渡邊優子、森崇寧、菊池絵梨子、湯浅磨里、藤井晋也、内田信一、影近弘之
- Organizer
  第３２回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] シラノール基を有する新規アンドロゲン受容体アンタゴニストの創製
- Author(s)
  山内夢人、藤井晋也、河内恵美子、増野弘幸、影近弘之
- Organizer
  日本レチノイド研究会第25回学術集会
- Place of Presentation
  秋田
- Year and Date
  2014-10-08 – 2014-10-09
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] ステロイド代替骨格としてのジフェニルメタン骨格～胆汁鬱滞性疾患治療薬への展開～
- Author(s)
  小針孝夫、細田信之介、貝沼雅彦、三澤隆、藤井晋也、橋本祐一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] クルクミン誘導体の構造展開による新規ＰＲアンタゴニストの創製
- Author(s)
  藤井晋也、山田歩、森修一、影近弘之
- Organizer
  日本ケミカルバイオロジー学会第９会年会
- Place of Presentation
  大阪大学（大阪）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] Design and Synthesis of C,C’-Diphenylcarborane Derivatives as Novel Progesterone Receptor Antagonists
- Author(s)
  Hiroyuki Kagechika, Eiichi Nakano, Ayumi Yamada, Yuki Takeuchi, Shuichi Mori, Hiroyuki Masuno, Shinya Fujii
- Organizer
  IMEBoron XV
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2014-08-24 – 2014-08-28
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] クルクミン誘導体の構造展開による新規ＰＲアンタゴニストの創製
- Author(s)
  藤井晋也、山田歩、森修一、影近弘之
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Synthesis and characterization of novel m-carborane-containing porphyrinoid
- Author(s)
  Shinya Fujii, Shotaro Iihama, Hiroyuki Kagechika
- Organizer
  IMEBORON 15
- Place of Presentation
  プラハ工科大学（チェコ）
- Year and Date
  2014-08-24 – 2014-08-28
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] ステロイド代替骨格としてのジフェニルメタン骨格―胆汁鬱滞性疾患治療薬への展開―
- Author(s)
  小針孝夫、細田信之助、貝沼雅彦、三澤隆、藤井晋也、橋本祐一
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸（兵庫）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] 核内受容体選択的なCoactivator Binding Inhibitorの創製研究
- Author(s)
  福田寛充、槇島誠、石川稔、藤井晋也、橋本祐一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] カルボラン含有プロゲステロン受容体リガンドのリパーゼによる光学分割
- Author(s)
  森修一、高垣亮平、藤井晋也、松村実生、棚谷綾、影近弘之
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸（兵庫）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] ホウ素クラスターを基盤としたビタミンDの構造展開
- Author(s)
  影近弘之、藤井晋也、増野弘幸
- Organizer
  第341回脂溶性ビタミン総合研究委員会
- Place of Presentation
  奈良女子大学（奈良）
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] 核内受容体選択的なCoactivator Binding Inhibitorの創製研究
- Author(s)
  福田寛充、槇島誠、石川稔、藤井晋也、橋本祐一
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸（兵庫）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] ケイ素とcisオレフィンの可換性に着目した含ケイ素PPARアゴニストの創製
- Author(s)
  梶田大資、中村雅陽、松本洋太郎、石川稔、橋本祐一、藤井晋也
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸（兵庫）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] Development of Transcriptional Modulators Using Three Dimensional Architectures
- Author(s)
  Shinya Fujii, Yasuyuki Endo, Hiroyuki Kagechika, Yuichi Hashimoto
- Organizer
  ICCEOCA-9_ACP2014
- Place of Presentation
  クアラルンプール（マレーシア）
- Year and Date
  2014-12-01 – 2014-12-04
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] ホウ素クラスターを基盤としたビタミンDの構造展開
- Author(s)
  影近弘之、藤井晋也、増野弘幸
- Organizer
  第341回脂溶性ビタミン総合研究委員会
- Place of Presentation
  奈良女子大学（奈良）
- Data Source
  KAKENHI-PROJECT-23659051
[Presentation] Lipase-catalyzed optical resolution and biological activity of boron-cluster-based progesterone receptor ligands
- Author(s)
  Shuichi Mori, Ryohei Takagaki, Shinya Fujii, Mio Matsumura, Aya Tanatani, Hiroyuki Kagechika
- Organizer
  3rd International Chemical Biology Meeting
- Place of Presentation
  San Fransisco, USA
- Year and Date
  2014-11-17 – 2014-11-20
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] 新規７－アミドクマリン誘導体のアンドロゲンアンタゴニスト活性
- Author(s)
  古賀瞳、木下満里絵、藤井晋也、影近弘之、棚谷綾
- Organizer
  日本レチノイド研究会第25回学術集会
- Place of Presentation
  秋田
- Year and Date
  2014-10-08 – 2014-10-09
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] カルボランを基盤とする非セコステロイド型VDRリガンドの疎水性部位の構造展開
- Author(s)
  藤井晋也、八田健司、増野弘幸、河内恵美子、影近弘之
- Organizer
  日本ビタミン学会第65回大会
- Place of Presentation
  姫路
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Synthesis and Characterization of Novel m-Ccarborane-Containing Porphyrinoid
- Author(s)
  Shinya Fujii, Shotaro Iihama, Hiroyuki Kagechika
- Organizer
  IMEBoron XV
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2014-08-24 – 2014-08-28
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] カルボランを基盤とする非セコステロイド型VDRリガンドの疎水性部位の構造展開
- Author(s)
  藤井晋也、八田健司、増野弘幸、河内恵美子、影近弘之
- Organizer
  日本ビタミン学会第６６回大会
- Place of Presentation
  姫路商工会議所（兵庫）
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-25460146
[Presentation] ケイ素とcisオレフィンの可換性に着目した含ケイ素PPARアゴニストの創製
- Author(s)
  梶田大資、中村雅陽、松本洋太郎、石川稔、橋本祐一、藤井晋也
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293025
[Presentation] クマリン骨格を基盤としたアンドロゲンアンタゴニストの創製研究
- Author(s)
  古賀瞳、木下満里絵、藤井晋也、影近弘之、棚谷綾
- Organizer
  第３２回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] カルボラン含有プロゲステロン受容体リガンドのリパーゼによる光学分割
- Author(s)
  森修一、高垣亮平、藤井晋也、松村実生、棚谷綾、影近弘之
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PLANNED-22136013
[Presentation] Design and synthesis of C,C'-diphenylcarborane derivatives as novel progesterone receptor antagonists
- Author(s)
  Hiroyuki Kagechika, Shuichi Mori, Eiichi Nakano, Ayumi Yamada, Yuki Takeuchi, Hiroyuki Masuno, Shinya Fujii
- Organizer
  IMEBORON 15
- Place of Presentation
  プラハ工科大学（チェコ）
- Year and Date
  2014-08-24 – 2014-08-28
- Data Source
  KAKENHI-PROJECT-25460146

1. KAGECHIKA Hiroyuki (20177348)

# of Collaborated Projects: 3 results

# of Collaborated Products: 73 results
2. ENDO Yasuyuki (80126002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
3. INOMATA Kohei (60221785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OHTA Kiminori (90347906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
5. FABIO Pichierri (40374920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIRANO Tomoya (20396980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. Hashimoto Yuichi (90164798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
8. ISHIKAWA Minoru (70526839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. YACHIDE Tomomi (20401284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NUMADATE Akiyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. NOGUCHI Tomomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. TAKITA Ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 棚谷綾

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
14. 頼建光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 内山真伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 湯浅磨里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 白川仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 駒井三千夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Fujii Shinya 藤井 晋也

藤井 晋也 フジイ シンヤ

FUJII Shinya 藤井 晋也

Research Projects

Research Products

Co-Researchers

Development of novel structural options in medicinal chemistry using phosphorus functionalitiesPrincipal Investigator

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Phosphinamide as 'the third amide species' in medicinal chemistry - expanding the chemical space of biofunctional moleculesPrincipal Investigator

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Fundamentals of multi-elemental medicinal chemistry for developing the novel and innovative drug candidatesPrincipal Investigator

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Development of novel nuclear receptor modulators based on the chemical posttranslational modificationsPrincipal Investigator

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Polypharmacology based on dynamism of the target protein

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Development of novel transcription modulators based on de novo design of scaffoldsPrincipal Investigator

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Development of novel vitamin K derivatives and elucidation of their biological functions

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Characterization and application of hydrophobic functionalities bearing heavier group 14 atomsPrincipal Investigator

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Development of specific modulators for nuclear receptors and elucidation of their functions

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Development of non-secosteroidal vitamin D receptor ligands based on novel hydrophobic core structurePrincipal Investigator

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Development of Receptor Regulators Utilizing Novel HydrophobicStructure and Its Application for Medicinal Drug Design

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イオン間相互作用をファーマコフォアとする次世代ビタミンD受容体リガンドの創製Principal Investigator

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[Journal Article] Design, Synthesis, and Evaluation of B-(Trifluoromethyl)phenyl Phosphine?Borane Derivatives as Novel Progesterone Receptor Antagonists2024

Author(s)

Fujii Shinya 藤井晋也

藤井晋也フジイシンヤ

FUJII Shinya 藤井晋也