Nakase Taizen 中瀬泰然

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NAKASE Taizen 中瀬泰然

中瀬泰然ナカセタイゼン

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Researcher Number	60390928
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Affiliation (Current)	2025: 東北大学, 加齢医学研究所, 准教授 2025: 秋田県立循環器・脳脊髄センター(研究所), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 東北大学, 加齢医学研究所, 准教授 2012: 秋田県立脳血管研究センター(研究局), 脳卒中医療システム研究部, 部長 2012: 秋田県立脳血管研究センター, 脳卒中医療システム研究部, 部長 2011: 秋田県立脳血管研究センター(研究部門), 脳卒中医療システム研究部, 部長 2010: 秋田県立脳血管研究センター(研究局), 脳卒中医療システム研究部, 部長 2005 – 2006: 秋田県立脳血管研究センター(研究局), 神経内科学研究部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery / Human pathology Except Principal Investigator Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 免疫組織染色 / 脳梗塞 / 慢性脳低灌流 / アルツハイマー病 / 病態モデル / 酸化型LDLレセプター / 抗CD68抗体 / 抗CD36抗体 / 内頸動脈内膜剥離術 / 内頚動脈内膜剥離術 … More / 脳血管障害 / 動脈硬化 / 神経病理学 / 脳血管障害学 / 蛍光抗体法 / コネキシン / ギャップ結合 / 星状膠細胞 … More Except Principal Investigator 慢性低酸素 / オートファジー障害 / MRI / 鉄 / オートファジー / アルツハイマー病 / 認知症 Less

認知症におけるオートファジー障害の病態解明とPADREによる超早期画像診断法の開発
- Principal Investigator
  
  瀧靖之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Tohoku University
慢性脳低灌流を加えた新規認知症モデルの開発と内皮機能障害メカニズムの解明Principal Investigator
- Principal Investigator
  
  中瀬泰然
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tohoku University
Exploring the pathological mechanism of gap junction regarding the progression of athromatous plaque.Principal Investigator
- Principal Investigator
  
  NAKASE Taizen
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  秋田県立脳血管研究センター
   秋田県立脳血管研究センター(研究部門)
脳虚血病態に及ぼすアストロサイトギャップ結合機能のヒト剖検脳を用いた検討Principal Investigator
- Principal Investigator
  
  中瀬泰然
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Research institute for Brain and Blood Vesseis Akita

All 2024 2023 2022 2021 2013 2012 2011 2010 2006 2005

All Journal Article Presentation Book

[Book] 急性期脳梗塞.総編集山口徹ら.今日の治療指針20132013
- Author(s)
  中瀬泰然
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] Impact of atrial fibrillation on the cognitive decline in Alzheimer's disease.2023
- Author(s)
  Nakase T, Tatewaki Y, Thyreau B, Odagiri H, Tomita N, Yamamoto S, Takano Y, Muranaka M, Taki Y.
- Journal Title
  
  Alzheimers Research and Therapy
  
  Volume: 15 Issue: 1 Pages: 1-8
- DOI
  10.1186/s13195-023-01165-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09169, KAKENHI-PROJECT-19K11637, KAKENHI-PROJECT-21K07665
[Journal Article] Association between Gray and White Matter Lesions and Its Involvement in Clinical Symptoms of Alzheimer’s-Type Dementia2023
- Author(s)
  Nakase Taizen、Thyreau Benjamin、Tatewaki Yasuko、Tomita Naoki、Takano Yumi、Muranaka Michiho、Taki Yasuyuki
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 24 Pages: 7642-7642
- DOI
  10.3390/jcm12247642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11637, KAKENHI-PROJECT-21K07665, KAKENHI-PROJECT-21K09169
[Journal Article] Impact of constipation on progression of Alzheimer's disease: A retrospective study2022
- Author(s)
  Nakase Taizen、Tatewaki Yasuko、Thyreau Benjamin、Mutoh Tatsushi、Tomita Naoki、Yamamoto Shuzo、Takano Yumi、Muranaka Michiho、Taki Yasuyuki
- Journal Title
  
  CNS Neuroscience & Therapeutics
  
  Volume: 28 Issue: 12 Pages: 1964-1973
- DOI
  10.1111/cns.13940
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11637, KAKENHI-PROJECT-21K09169
[Journal Article] Clinical evaluation of lacunar infarction and branch atheromatous disease2013
- Author(s)
  Taizen Nakase, Shotaroh Yoshioka, Masahiro Sasaki, Akifumi Suzuki
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 22 Pages: 406-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] Clinical Evaluation of Lacunar Infarction and Branch Atheromatous Disease2012
- Author(s)
  Nakase T, Yoshioka S, Sasaki M, Suzuki A
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] 脳出血後の血圧日内変動パターンの変化についての24時間血圧計を用いた検討。2012
- Author(s)
  中瀬泰然
- Journal Title
  
  脳卒中
  
  Volume: 34 Pages: 215-220
- NAID
  130004873567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] Clinical features of recurrent stroke after intracerebral hemorrhage.2012
- Author(s)
  Nakase T.
- Journal Title
  
  Neurology International
  
  Volume: 4 Issue: 2 Pages: 10-10
- DOI
  10.4081/ni.2012.e10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] 脳出血後の血圧日内変動パターンの変化についての24時間血圧計を用いた検討2012
- Author(s)
  中瀬泰然、吉岡正太郎、佐々木正弘、鈴木明文
- Journal Title
  
  脳卒中
  
  Volume: (In press)
- NAID
  130004873567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] Clinical features of recurrent stroke after intracerebral hemorrhage2012
- Author(s)
  Taizen Nakase, Shotaroh Yoshioka, Masahiro Sasaki, Akifumi Suzuki
- Journal Title
  
  Neurol Int
  
  Volume: 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] 脳出血後の血圧日内変動パターンの変化についての24時間」血圧計を用いた検討2012
- Author(s)
  中瀬泰然、亀田知明、鈴木明文、長田乾
- Journal Title
  
  脳卒中
  
  Volume: 34 Pages: 215-220
- NAID
  130004873567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] Free radical scavenger, edaravone, reduces the lesion size of lacunar infarction in human brain ischemic stroke2011
- Author(s)
  Nakase T, Yoshioka S, Suzuki A
- Journal Title
  
  BMC Neurology
  
  Volume: 11 Pages: 39-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] Free radical scavenger, edaravone, reduces the lesion size of lacunar infarction in human brain ischemic stroke2011
- Author(s)
  D Taizen Nakase, Shotaroh Yoshioka, Akifumi Suzuki
- Journal Title
  
  BMC Neurol
  
  Volume: 11 Issue: 1 Pages: 39-39
- DOI
  10.1186/1471-2377-11-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] 進歩する脳梗塞医療2010
- Author(s)
  中瀬泰然
- Journal Title
  
  秋田県医師会雑誌
  
  Volume: 60 Pages: 8-13
- NAID
  40017004827
- Data Source
  KAKENHI-PROJECT-22591601
[Journal Article] 経過中に脳塞栓症を再発した椎骨動脈解離の1例2006
- Author(s)
  中瀬泰然, 鈴木明文, 岡根久美子, 長田乾
- Journal Title
  
  脳と神経 58
  
  Pages: 239-243
- Data Source
  KAKENHI-PROJECT-17790247
[Journal Article] Amplified expression of connexin 43 in astrocytes in the human brain following ischemic stroke2006
- Author(s)
  Nakase T, Yoshida Y, Nagata K
- Journal Title
  
  GLIA 54
  
  Pages: 369-375
- Data Source
  KAKENHI-PROJECT-17790247
[Journal Article] 脳梗塞急性期における炎症マーカーの測定-予後および経過の指標としての検討-2006
- Author(s)
  中瀬泰然, 佐藤美佳, 山崎貴史, 小倉直子, 鈴木明文, 長田乾
- Journal Title
  
  脳卒中 28
  
  Pages: 360-365
- NAID
  10018392894
- Data Source
  KAKENHI-PROJECT-17790247
[Journal Article] Cx43 expression and neuroprotection in human ischemic brain injury.2005
- Author(s)
  Nakase T, Yoshida Y, Nagata K.
- Journal Title
  
  Journal of Neurological Sciences 238(S1)
- Data Source
  KAKENHI-PROJECT-17790247
[Presentation] 認知症病態に影響を及ぼす脳卒中関連要因の検討2024
- Author(s)
  中瀬泰然
- Organizer
  日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09169
[Presentation] アルツハイマー型認知症周辺症状に対する各種治療薬の効果についての検討2022
- Author(s)
  中瀬泰然、舘脇康子、冨田尚希、高野由美、村中美千帆、山本修三、瀧　靖之
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09169
[Presentation] Association between constipation and progression of Alzheimer's disease.2022
- Author(s)
  Nakase Taizen, Yasuko Tatewaki, Benjamin Thyreau, Naoki Tomita, Syuzo Yamamoto, Yumi Takano, Michiho Muranaka, Yasuyuki Taki
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09169
[Presentation] アルツハイマー型認知症の進行に影響する心房細についての検討2022
- Author(s)
  中瀬泰然、舘脇康子、Benjamin Thyreau、冨田尚希、山本修三、高野由美、村中美千帆、瀧靖之
- Organizer
  第64回日本老年医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09169
[Presentation] アルツハイマー病の進行に関与する便秘の影響についての検討2021
- Author(s)
  中瀬泰然、舘脇康子、Benjamin Thyreau、冨田尚希、山本修三、高野由美、村中美千帆、瀧靖之
- Organizer
  第40回日本認知症学会学術集会．Web開催
- Data Source
  KAKENHI-PROJECT-21K09169
[Presentation] Exploring The Better Medication for Small Vessel Disease of Brain Infarction2012
- Author(s)
  T Nakase
- Organizer
  The 2nd International Conference on Pharmaceutica-2012
- Place of Presentation
  San Francisco, USA
- Year and Date
  2012-02-20
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] 超急性期血栓溶解療法における炎症反応の変化について、通常治療との比較検討2012
- Author(s)
  中瀬泰然、吉岡正太郎、池田靖子、佐々木正弘、鈴木明文
- Organizer
  53回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2012-05-22
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] Anti-platelet medication for the progressing stroke with small vessel occlusion2012
- Author(s)
  O Nakase T, Sasaki M, Yoshioka S, Ikeda Y, Suzuki A
- Organizer
  58^<th> Annual meeting of the scientific and standardizationcommittee of the ISTH
- Place of Presentation
  Liverpool, UK.
- Year and Date
  2012-06-27
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] 穿通枝脳梗塞に対する急性期治療の検討。2012
- Author(s)
  中瀬泰然
- Organizer
  第37回日本脳卒中学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] 超急性期血栓溶解療法における炎症反応の変化について。通常治療との比較検討。2012
- Author(s)
  中瀬泰然
- Organizer
  第53回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] Anti-Platelet Medication for The Progressing Stroke with Small Vessels Occlusion.2012
- Author(s)
  Nakase T.
- Organizer
  58th Annual Meeting of the Scientific and Standardization Committee of the ISTH.
- Place of Presentation
  Liverpool, UK
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] Altered Inflammatory Response After Acute rt-PA Thrombolytic Therepy in Ischemic Stroke Patient.2012
- Author(s)
  Nakase T.
- Organizer
  2nd Russian Congress with International Participation Molecular Basis of Clinical Medicine.
- Place of Presentation
  Saint Peterbrug, Russia
- Invited
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] ラクナ梗塞とBranch Atheromatous Diseaseに対する急性期治療の検討2011
- Author(s)
  中瀬泰然
- Organizer
  第36回日本脳卒中学会総会
- Place of Presentation
  京都市
- Year and Date
  2011-07-31
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] The free radical scavenger can effect on the inflammatory biomarkers in acute ischemic stroke following thrombolysis with rt-PA2011
- Author(s)
  T Nakase
- Organizer
  10th World congress on inflammation
- Place of Presentation
  Paris, France
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] ラクナ梗塞とBranch Atheromatous Diseaseに対する急性期治療の検討2011
- Author(s)
  中瀬泰然、吉岡正太郎、佐々木正弘、鈴木明文
- Organizer
  36回脳卒中学会総会
- Place of Presentation
  京都
- Year and Date
  2011-07-31
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] 脳梗塞急性期における安全な血圧レベルは?-SPECTによる脳」血流の評価から-2011
- Author(s)
  中瀬泰然、吉岡正太郎、佐々木正弘、鈴木明文
- Organizer
  52回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] アテローム硬化性病変における酸化型LDLレセプターCD36の発現に関する免疫組織化学的検討2011
- Author(s)
  中瀬泰然
- Organizer
  第52回日本神経病理学会総会学術研究会
- Place of Presentation
  京都市
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] アテローム硬化性病変における酸化型LDLレセプターCD36の発現に関する免疫組織化学的検討2011
- Author(s)
  中瀬泰然、玉川紀之、金子妙子、宮田元
- Organizer
  52回神経病理学会
- Place of Presentation
  京都
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] Lower safety level of blood pressure in the patient of acute cerebral infarction2011
- Author(s)
  T Nakase
- Organizer
  Australian Neuroscience Society 31^<st> Annual Meeting
- Place of Presentation
  Auckland, New Zealand
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] 脳梗塞急性期における安全な血圧レベルは?-SPECTによる脳血流量の評価から-2011
- Author(s)
  中瀬泰然
- Organizer
  第52回日本神経学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] 脳卒中初期診療における現状と問題点秋田の場合2010
- Author(s)
  中瀬泰然
- Organizer
  第24回東北救急医学会総会
- Place of Presentation
  横手市
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] ラクナ梗塞とBranch Atheromatous Diseaseの臨床的特徴:症状進行性の有無からの検討2010
- Author(s)
  中瀬泰然
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] 脳出血症例の脳卒中再発に関わる要因の検討2010
- Author(s)
  中瀬泰然
- Organizer
  第35回日本脳卒中学会総会
- Place of Presentation
  盛岡市
- Data Source
  KAKENHI-PROJECT-22591601
[Presentation] Neuroprotective Role of Connexins in The Central Nervous System2010
- Author(s)
  T Nakase
- Organizer
  6^<th> International Symposium on Neuroprotection & Neurorepair
- Place of Presentation
  Rostock, Germany
- Data Source
  KAKENHI-PROJECT-22591601

1. 板東良雄 (20344575)

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2. 清水宏明 (20506638)

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3. 瀧靖之 (10375115)

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4. 古本祥三 (00375198)

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9. 関根弘樹 (50506285)

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Nakase Taizen 中瀬 泰然

NAKASE Taizen 中瀬 泰然

中瀬 泰然 ナカセ タイゼン

Research Projects

Research Products

Co-Researchers

認知症におけるオートファジー障害の病態解明とPADREによる超早期画像診断法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

慢性脳低灌流を加えた新規認知症モデルの開発と内皮機能障害メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring the pathological mechanism of gap junction regarding the progression of athromatous plaque.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳虚血病態に及ぼすアストロサイトギャップ結合機能のヒト剖検脳を用いた検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 急性期脳梗塞.総編集山口徹ら.今日の治療指針20132013

Author(s)

Publisher

Data Source

[Journal Article] Impact of atrial fibrillation on the cognitive decline in Alzheimer's disease.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between Gray and White Matter Lesions and Its Involvement in Clinical Symptoms of Alzheimer’s-Type Dementia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of constipation on progression of Alzheimer's disease: A retrospective study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical evaluation of lacunar infarction and branch atheromatous disease2013

Author(s)

Journal Title

Data Source

[Journal Article] Clinical Evaluation of Lacunar Infarction and Branch Atheromatous Disease2012

Author(s)

Journal Title

Data Source

[Journal Article] 脳出血後の血圧日内変動パターンの変化についての24時間血圧計を用いた検討。2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Clinical features of recurrent stroke after intracerebral hemorrhage.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 脳出血後の血圧日内変動パターンの変化についての24時間血圧計を用いた検討2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Clinical features of recurrent stroke after intracerebral hemorrhage2012

Author(s)

Journal Title

Data Source

[Journal Article] 脳出血後の血圧日内変動パターンの変化についての24時間」血圧計を用いた検討2012

Author(s)

Journal Title

NAID

Nakase Taizen 中瀬泰然

NAKASE Taizen 中瀬泰然

中瀬泰然ナカセタイゼン