Takenobu Hisanori 竹信尚典

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TAKENOBU Hisanori 竹信尚典

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Researcher Number	60392247
Affiliation (Current)	2025: 地方独立行政法人埼玉県立病院機構埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員
Affiliation (based on the past Project Information) *help	2024: 地方独立行政法人埼玉県立病院機構埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員 2021 – 2022: 地方独立行政法人埼玉県立病院機構埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員 2020: 埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員 2016 – 2018: 埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員 2015: 埼玉県立がんセンター(臨床腫瘍研究所), その他部局等, 研究員 … More 2014: 埼玉県立がんセンター(臨床腫瘍研究所), その他部局等, 専門研究員 2014: 千葉県がんセンター(研究所), その他部局等, 研究員 2014: 千葉県がんセンター, 研究所, 研究員 2011 – 2013: 千葉県がんセンター(研究所), 発がん研究グループ, 研究員 2012: 千葉県がんセンター(研究所), 発がん制御研究部, 研究員 2008 – 2010: Chiba Cancer Center (Research Institute), 発がん制御研究部, 研究員 2009: Chiba Cancer Center (Research Institute), 千葉県がんセンター(研究所)発がん制御研究部, 研究員 2007: Chiba Cancer Center (Research Institute), 生化学研究部, 研究員 2005 – 2007: 千葉県がんセンター(研究所), 病理研究部, 研究員 Less
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 49010:Pathological biochemistry-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Human pathology Except Principal Investigator General medical chemistry / Pediatric surgery / Pediatrics
Keywords	Principal Investigator 発がん / 細胞分化 / 幹細胞 / 分化 / トランスジェニック動物 / 転写因子 / iPS / 神経芽腫 / iPS細胞 / 分子標的 / 小児腫瘍学 … More Except Principal Investigator … More がん幹細胞 / p63 / p73 / XCE / nestin / 癌 / 神経芽腫 / Cancer stem cell / Hypoxia / Tissue・Cell / Cancer / 低酸素 / 組織・細胞 / CD 133 / Stem cell markers / Cancer stem cells / Neuroblastoma / p53 / TUJ1 / CD133 / 幹細胞マーカー / 小児腫瘍学 / 小児がん / 遺伝子 / 網羅的解析 / 腫瘍スフェア / 癌幹細胞 Less

Elucidating epigenetic modifications induced by oncogenic transcription factor CDXs in cancer cellsPrincipal Investigator
- Principal Investigator
  
  竹信尚典
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Research Institute for Clinical Oncology Saitama Cancer Center
Discover for the second-hit gene regions using comprehensive gene destruction in neuroblastoma carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Takenobu Hisanori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Research Institute for Clinical Oncology Saitama Cancer Center
Single cell screening of molecular target in using malignant neuroblastoma animal modelPrincipal Investigator
- Principal Investigator
  
  Takenobu Hisanori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
A novel therapeutic targeting of CD133 transcription in malignant neuroblastomaPrincipal Investigator
- Principal Investigator
  
  Takenobu Hisanori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
  Chiba Cancer Center (Research Institute)
Development of cancer stem cell-targeted therapy by study of tumor sphere formation mechanism using comprehensive and genetic approach
- Principal Investigator
  
  KAMIJO Takehiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
  Chiba Cancer Center (Research Institute)
Identification of tumor stem-specific transcription factor in neuroblastoma spherePrincipal Investigator
- Principal Investigator
  
  TAKENOBU Hisanori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Chiba Cancer Center (Research Institute)
Identification and functional analysis of novel stem cell markers in neuronal-related cellsPrincipal Investigator
- Principal Investigator
  
  TAKENOBU Hisanori
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Chiba Cancer Center (Research Institute)
Analysis of the effects of tumor hypoxia on dynamics of cancer stem cells
- Principal Investigator
  
  KEIZO Takenaga
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Chiba Cancer Center (Research Institute)
Identification of Cancer Stem Cells and Its Clinical Application for Treating Aggressive Neuroblastomas
- Principal Investigator
  
  NAKAGAWARA Akira
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  Chiba Cancer Center Research Institute

[Journal Article] Platelet-to-Lymphocyte Ratio Predicts the Efficacy of Pembrolizumab in Patients With Urothelial Carcinoma.2022
- Author(s)
  Kurashina R, Ando K, Inoue M, Izumi K, Maruyama R, Mitani K, Takenobu H, Haruta M, Iizuka T, Kamijo T, Kageyama Y.
- Journal Title
  
  Anticancer Res.
  
  Volume: 42 Issue: 2 Pages: 1131-1136
- DOI
  10.21873/anticanres.15576
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07579, KAKENHI-PROJECT-20K08174, KAKENHI-PROJECT-19H03625
[Journal Article] Polycomb EZH1 regulates cell cycle/5‐fluorouracil sensitivity of neuroblastoma cells in concert with MYCN2022
- Author(s)
  Shinno Yoshitaka、Takenobu Hisanori、Sugino Ryuichi P.、Endo Yuki、Okada Ryu、Haruta Masayuki、Satoh Shunpei、Mukae Kyosuke、Shaliman Dilibaerguli、Wada Tomoko、Akter Jesmin、Ando Kiyohiro、Nakazawa Atsuko、Yoshida Hideo、Ohira Miki、Hishiki Tomoro、Kamijo Takehiko
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 12 Pages: 4193-4206
- DOI
  10.1111/cas.15555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08269, KAKENHI-PROJECT-22K15517, KAKENHI-PROJECT-20K08174, KAKENHI-PROJECT-19H03625
[Journal Article] The PRC2 molecule EED is a target of epigenetic therapy for neuroblastoma2022
- Author(s)
  Shaliman Dilibaerguli、Takenobu Hisanori、Sugino Ryuichi P.、Ohira Miki、Kamijo Takehiko
- Journal Title
  
  European Journal of Cell Biology
  
  Volume: 101 Issue: 3 Pages: 151238-151238
- DOI
  10.1016/j.ejcb.2022.151238
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08269, KAKENHI-PROJECT-20K08174, KAKENHI-PROJECT-19H03625
[Journal Article] Loss of p53 suppresses replication stress-induced DNA damage in ATRX-deficient neuroblastoma2021
- Author(s)
  Akter Jesmin、Katai Yutaka、Sultana Parvin、Takenobu Hisanori、Haruta Masayuki、Sugino Ryuichi P.、Mukae Kyosuke、Satoh Shunpei、Wada Tomoko、Ohira Miki、Ando Kiyohiro、Kamijo Takehiko
- Journal Title
  
  Oncogenesis
  
  Volume: 10 Issue: 11 Pages: 1256-1256
- DOI
  10.1038/s41389-021-00363-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15256, KAKENHI-PROJECT-19K16759, KAKENHI-PROJECT-20K07579, KAKENHI-PROJECT-20K08174, KAKENHI-PROJECT-20K08269, KAKENHI-PROJECT-19H03625
[Journal Article] EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications2018
- Author(s)
  Li Zhenghao、Takenobu Hisanori、Setyawati Amallia Nuggetsiana、Akita Nobuhiro、Haruta Masayuki、Satoh Shunpei、Shinno Yoshitaka、Chikaraishi Koji、Mukae Kyosuke、Akter Jesmin、Sugino Ryuichi P.、Nakazawa Atsuko、Nakagawara Akira、Aburatani Hiroyuki、Ohira Miki、Kamijo Takehiko
- Journal Title
  
  Oncogene
  
  Volume: 37 Issue: 20 Pages: 2714-2727
- DOI
  10.1038/s41388-018-0133-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10131, KAKENHI-PROJECT-18K15256, KAKENHI-PROJECT-17H01592, KAKENHI-PROJECT-16K10051, KAKENHI-PROJECT-17K19623
[Journal Article] CFC1 is a cancer stemness-regulating factor in neuroblastoma2017
- Author(s)
  Chikaraishi Koji、Takenobu Hisanori、Sugino Ryuichi P.、Mukae Kyosuke、Akter Jesmin、Haruta Masayuki、Kurosumi Masafumi、Endo Takaho A.、Koseki Haruhiko、Shimojo Naoki、Ohira Miki、Kamijo Takehiko
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 28 Pages: 45046-45059
- DOI
  10.18632/oncotarget.18464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10051, KAKENHI-PROJECT-17K10131, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-17H01592, KAKENHI-PROJECT-17K19623
[Journal Article] Receptor-type protein tyrosine phosphatase κ directly dephosphorylates CD133 and regulates downstream AKT activation.2015
- Author(s)
  Shimozato O, Waraya M, Nakashima K, Souda H, Takiguchi N, Yamamoto H, Takenobu H, Uehara H, Ikeda E, Matsushita S, Kubo N, Nakagawara A, Ozaki T, Kamijo T.
- Journal Title
  
  Oncogene
  
  Volume: 34 Pages: 1949-1960
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461614
[Journal Article] Novel 1p tumour suppressor Dnmt1-associated protein 1 regulates MYCN/ataxia telangiectasia mutated/p53 pathway.2014
- Author(s)
  Yamaguchi Y, Takenobu H, Ohira M, Nakazawa A, Yoshida S, Akita N, Shimozato O, Iwama A, Nakagawara A, Kamijo T.
- Journal Title
  
  Eur J Cancer
  
  Volume: 50 Issue: 8 Pages: 1555-1565
- DOI
  10.1016/j.ejca.2014.01.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592624, KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-24390269, KAKENHI-PROJECT-25253095, KAKENHI-PROJECT-25461614
[Journal Article] Receptor-type protein tyrosine phosphatasedirectly dephosphorylates CD133 and regulates downstream AKT activation2014
- Author(s)
  Shimozato O, Souda H
- Journal Title
  
  Oncogene
  
  Volume: 34(15) Issue: 15 Pages: 1-12
- DOI
  10.1038/onc.2014.141
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591978, KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-24390269, KAKENHI-PROJECT-26462721, KAKENHI-PROJECT-15K08412
[Journal Article] Bmi1 regulates cell fate via tumor suppressor WWOX repression in small-cell lung cancer cells.2011
- Author(s)
  Kimura M, Takenobu H, Akita N, Nakazawa A, Ochiai H, Shimozato O, Fujimura YI, Koseki H, Yoshino I, Kimura H, Nakagawara A, Kamijo T.
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 983-990
- NAID
  10029293384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791017
[Journal Article] CD133 suppresses neuroblastoma cell differentiation via signal pathway modification.2011
- Author(s)
  Takenobu H, Shimozato O, Nakamura T, Ochiai H, Yamaguchi Y, Ohira M, Nakagawara A, Kamijo T.
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 97-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791017
[Journal Article] CD133 suppresses neuroblastoma cell differentiation via signal pathway modification2011
- Author(s)
  Takenobu H, Shimozato O, Nakamura T, Ochiai H, Yamaguchi Y, Ohira M, Nakagawara A, Kamijo T
- Journal Title
  
  Oncogene
  
  Volume: 30 Issue: 1 Pages: 97-105
- DOI
  10.1038/onc.2010.383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390317, KAKENHI-PROJECT-21591376, KAKENHI-PROJECT-21790397, KAKENHI-PROJECT-22680065, KAKENHI-PROJECT-22791017
[Journal Article] CD133 suppresses neuroblastoma cell differentiation via signal pathway modification2011
- Author(s)
  Takenobu H, Shimozato 0, Nakamura T, Ochiai H, Yamaguchi Y, Ohira M, Nakagawara A, Kamijo T
- Journal Title
  
  Oncogene 2011
  
  Volume: 6;30(1) Pages: 97-105
- Data Source
  KAKENHI-PROJECT-22791017
[Journal Article] Bmi1 regulates cell fate via tumor suppressor WWOX repression in small cell lung cancer cells2011
- Author(s)
  Kimura M, Takenobu H, Akita N, Nakazawa A, Ochiai H, Shimozato O, Fujimura YI, Koseki H, Yoshino I, Kimura H, Nakagawara A, Kamijo T
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 5 Pages: 983-990
- DOI
  10.1111/j.1349-7006.2011.01891.x
- NAID
  10029293384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390317, KAKENHI-PROJECT-21790397, KAKENHI-PROJECT-22791017, KAKENHI-PROJECT-23591978
[Journal Article] HDM2 impairs Noxa transcription and affects apoptotic cell death in a p53/p73-dependent manner in neuroblastoma.2010
- Author(s)
  Shi Y, Takenobu H, Kurata K, Yamaguchi Y, Yanagisawa R, Ohira M, Koike K, Nakagawara A, Ling LJ, Kamijo T.
- Journal Title
  
  Eur. J. Cancer. (in press)
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] HDM2 impairs Noxa transcription and affects apoptotic cell death in a p53/p73-dependent manner in neuroblastoma.2010
- Author(s)
  Shi Y, Takenobu H, Kurata K, Yamaguchi Y, Yanagisawa R, Ohira M, Koike K, Nakagawara A, Jiang LL, Kamijo T.
- Journal Title
  
  European Journal of Cancer
  
  Volume: 46 Pages: 2324-2334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791017
[Journal Article] Bmil is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma.2010
- Author(s)
  Ochiai H, Takenobu H, Nakagawa A, Yamaguchi Y, Kimura M, Ohira M, Okimoto Y, Fujimura Y, Koseki H, Kohno Y, Nakagawara A, Kamijo T.
- Journal Title
  
  Oncogene 29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] Polycomb group molecule PHC3 regulates polycomb complex composition and prognosis of osteosarcoma.2010
- Author(s)
  Iwata S, Takenobu H, Kageyama H, Koseki H, Ishii T, Nakazawa A, Tatezaki SI, Nakagawara A, Kamijo T.
- Journal Title
  
  Cancer Sci. (Epub ahead of print)
- NAID
  10026594687
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma.2010
- Author(s)
  Ochiai H, Takenobu H, Nakagawa A, Yamaguchi Y, Kimura M, Ohira M, Okimoto Y, Fujimura Y, Koseki H, Kohno Y, Nakagawara A, Kamijo T.
- Journal Title
  
  Oncogene. 29(18)
  
  Pages: 2681-2690
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] Bmil is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma.2010
- Author(s)
  Ochiai H, Takenobu H, Nakagawa A, Yamaguchi Y, Kimura M, Ohira M, Okimoto Y, Fujimura Y, Koseki H, Kohno Y, Nakagawara A, Kamijo T.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2681-2690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791017
[Journal Article] Polycomb group molecule PHC3 regulates polycomb complex composition and prognosis of osteosarcoma2010
- Author(s)
  Iwata S, Takenobu H, Kageyama H, Koseki H, Ishii T, Nakazawa A, Tatezala S, Nakagawara A, Kamijo S.
- Journal Title
  
  Cancer Science
- NAID
  10026594687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] Polycomb group molecule PHC3 regulates polycomb complex composition and prognosis of osteosarcoma2010
- Author(s)
  Iwata S, Takenobu H, Kageyama H, Koseki H, Ishii T, Nakazawa A, Tatezaki S, Nakagawara A, Kamijo S.
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 1646-1652
- NAID
  10026594687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791017
[Journal Article] Plk1 regulates liver tumor cell death by phosphorylation of TAp63.2009
- Author(s)
  Komatsu S, Takenobu H, Ozaki T, Ando K, Koida N, Suenaga Y, Ichikawa T, Hishiki T, Chiba T, Iwama A, Yoshida H, Ohnuma N, Nakagawara A, Kamijo T.
- Journal Title
  
  Oncogene 28
  
  Pages: 3631-3641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] Plk1 regulates liver tumor cell death by phosphorylation of TAp63.2009
- Author(s)
  Komatsu S, Takenobu H, Ozaki T, Ando K, Koida N, Suenaga Y, Ichikawa T, Hishiki T, Chiba T, Iwama A, Yoshida H, Ohnuma N, Nakagawara A, Kamijo T.
- Journal Title
  
  Oncogene. 28(41)
  
  Pages: 3631-3941
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma.2008
- Author(s)
  Hossain MS, Ozaki T, Wang H, Nakagawa A, Takenobu H, Ohira M, Kamiio T, Nakaerawara A.
- Journal Title
  
  Oncogene 27
  
  Pages: 6075-6082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma.2008
- Author(s)
  Hossain MS, Ozaki T, Wang H, Nakagawa A, Takenobu H, Ohira M, Kamijo T, Nakagawara A.
- Journal Title
  
  Oncogene. 27(46)
  
  Pages: 6075-6082
- Data Source
  KAKENHI-PROJECT-19790274
[Journal Article] Polycomb group molecule PHC3 regulates polycomb complex composition and prognosis of osteosarcoma
- Author(s)
  Iwata S, Takenobu H, Kageyama H, Koseki H, Ishii T, Nakazawa A, Tatezaki S, Nakagawara A, Kamijo T
- Journal Title
  
  Cancer Sci
  
  Volume: 101(7) Pages: 1646-1652
- NAID
  10026594687
- Data Source
  KAKENHI-PROJECT-22791017
[Journal Article] Bmil regulates cell fate via tumor suppressor WWOX repression in small-cell lung cancer cells
- Author(s)
  Kimura M, Takenobu H, Akita N, Nakazawa A, Ochiai H, Shimozato 0, Fujimura Y, Koseki H, Yoshino I, Kimura H, Nakagawara A, Kamijo T
- Journal Title
  
  Cancer Sci
  
  Volume: 102(5) Pages: 983-990
- Data Source
  KAKENHI-PROJECT-22791017
[Journal Article] HDM2 impairs Noxa transcription and affects apoptotic cell death in a p53/p73-dependentmanner in neuroblastoma
- Author(s)
  Shi Y, Takenobu H, Kurata K, Yamaguchi Y, Yanagisawa R, Ohira M, Koike K, Nakagawara A, Jiang LL, Kamijo T
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(12) Pages: 2324-2334
- Data Source
  KAKENHI-PROJECT-22791017
[Patent] CDX1測定による神経芽腫の悪性度の決定と予後判定2013
- Inventor(s)
  上條岳彦、竹信尚典
- Industrial Property Rights Holder
  千葉県
- Industrial Property Number
  2013-002842
- Filing Date
  2013-01-10
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] CDX1は遺伝子発現制御を介して神経芽腫細胞における幹細胞性および増殖の制御をする2022
- Author(s)
  竹信尚典、杉野隆一、大平美紀、春田雅之、佐藤俊平、迎恭輔、和田朋子、岡田龍、ディルバーサルマン、上條岳彦
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K08174
[Presentation] PRC2阻害とエピジェネティック阻害剤を組み合わせた神経芽腫の効果的な治療法の開発2022
- Author(s)
  竹信尚典、遠藤悠紀、ディルバーサルマン、秦佳孝、大平美紀、杉野隆一、岡田龍、春田雅之、佐藤俊平、迎恭輔、ジェスミンアクター、和田朋子、中澤温子、上條岳彦
- Organizer
  第81回日本癌学会
- Data Source
  KAKENHI-PROJECT-20K08174
[Presentation] スフェア特異的転写因子CDX1はヒストン修飾変化をともなって幹細胞特異的な遺伝子発現を制御する2022
- Author(s)
  竹信尚典、杉野隆一、春田雅之、大平美紀、佐藤俊平、上條岳彦
- Organizer
  第１５回日本エピジェネティクス研究会
- Data Source
  KAKENHI-PROJECT-20K08174
[Presentation] パイオニア転写因子CDX1は神経芽腫細胞における発生関連遺伝子の発現を制御する2021
- Author(s)
  竹信尚典、杉野隆一、大平美紀、春田雅之、迎恭輔、和田朋子、力石浩志、遠藤悠紀、秋田直洋、岡田龍、ディルバーサルマン、上條岳彦
- Organizer
  第80回日本がん学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08174
[Presentation] 神経芽腫における分化関連遺伝子のエピジェネティックな発現抑制メカニズムの解明2021
- Author(s)
  Hisanori Takenobu, Zhenghao Li, Ryuichi P. Sugino, Kyosuke Mukae, Miki Ohira, Masayuki Haruta, Yuki Endo, Ryu Okada, Dilibaerguli Shaliman, Sultana Parvin, Takehiko Kamijo
- Organizer
  第14回日本エピジェネティック研究会年会
- Data Source
  KAKENHI-PROJECT-20K08174
[Presentation] p53 deficiency limits ATRX loss induced replication stress and genome instability in neuroblastoma cells2020
- Author(s)
  Jesmin Akter, Parvin Sultana, Hisanori Takenobu, Miki Ohira, Ryuichi Sugino, Masayuki Haruta, Takehiko Kamijo
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08174
[Presentation] Tumor sphere specific gene CDX1 binds to OCT4 and MAX promoters to regulates stemness2020
- Author(s)
  Hisanori Takenobu, Miki Ohira, Ryuichi Sugino, Dilibaerguli Shaliman, Koji Chikaraishi, Ryu Okada, Kyosuke Mukae, Tomoko Wada, Yuki Endo, Nobuhiro Akita, Masayuki Haruta, Takehiko Kamijo
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08174
[Presentation] iPS細胞由来神経堤細胞からの人工的発がんモデル開発2020
- Author(s)
  Kyosuke Mukae, Hisanori Takenobu, Hiroaki Kanda, Miki Ohira, Yuki Endo, Masayuki Haruta, Junya Toguchida, Kenji Osafune, Tatsutoshi Nakahata, Takehiko Kamijo
- Organizer
  第62回日本小児血液・癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08174
[Presentation] CFC1 is a cancer stemness-regulating factor in neuroblastoma.2018
- Author(s)
  Chikaraishi K, Takenobu H, Sugino RP, Mukae K, Akter J, Haruta M, Kurosumi M, Endo TA, Koseki H, Shimojo N, Ohira M, Kamijo T
- Organizer
  Advanced Neuroblastoma Research 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications2018
- Author(s)
  Zhenghao Li, Hisanori Takenobu, Amallia Nuggetsiana Setyawati, Nobuhiro Akita, Masayuki Haruta, Shunpei Satoh, Yoshitaka Shinno, Koji Chikaraishi, Kyosuke Mukae, Jesmin Akter, Ryuichi P. Sugino, Atsuko Nakazawa, Akira Nakagawara, Hiroyuki Aburatani, Miki Ohira, Takehiko Kamijo
- Organizer
  第60回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] CDX1 regulates stemness through MYC pathway modulation and reprogramming gene activation in neuroblastoma2018
- Author(s)
  Hisanori Takenobu, Miki Ohira, Ryuichi Sugino, Koji Chikaraishi, Ryu Okada, Kyosuke Mukae, Yuki Endo, Parvin Sultana, Yutaka Katai, Nobuhiro Akita, Masayuki Haruta, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Screening of EZH2i effector molecules in neuroblastoma by multi-omics analysis2018
- Author(s)
  Yuki Endo, Hisanori Takenobu, Ryuichi Sugino, Masayuki Haruta, Kyosuke Mukae, Shunpei Satoh, Yoshitaka Shinno, Mariko Hasegawa, Ryu Okada, Yutaka Katai, Masaki Nio, Miki Ohira, Takehiko Kamijo
- Organizer
  第60回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Effect of ATRX deletion by CRISPR-Cas9 system in neuroblastoma2018
- Author(s)
  Yutaka Katai, Jesmin Akter, Hisanori Takenobu, Miki Ohira, Ryuichi Sugino, Masayuki Haruta, Shunpei Satoh, Kyosuke Mukae, Parvin Sultana, Takehiko Kamijo
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Neuroblastoma cell dedifferentiation via epigenetic modification2018
- Author(s)
  Hisanori Takenobu, Ryuichi P. Sugino, Miki Ohira, Takehiko Kamijo
- Organizer
  第41回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Development of neuroblastoma model from iPS-based neural crest cells for analysis of neuroblastoma tumorigenesis2018
- Author(s)
  Kyosuke Mukae, Hisanori Takenobu, Ryuichi Sugino, Miki Ohira, Shunpei Satoh, Yuki Endo, Ryu Okada, Masayuki Haruta, Junya Toguchida, Kenji Osafune, Tatsutoshi Nakahata, Takehiko Kamijo
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] CDX1 regulates neuroblastoma stemness through MYC pathway modulation and reprogramming gene activation2018
- Author(s)
  Hisanori Takenobu, Miki Ohira, Ryuichi Sugino, Koji Chikaraishi, Kyosuke Mukae, Nobuhiro Akita, Masayuki Haruta, Akira Nakagawara, Manabu Nakayama, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  Advanced Neuroblastoma Research 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Reevaluation of PDGFRα signal in neuroblastoma: high expression and a new nonsynonymous mutation2018
- Author(s)
  Shunpei Satoh, Miki Ohira, Hisanori Takenobu, Akira Nakagawara, Takehiko Kamijo
- Organizer
  Advanced Neuroblastoma Research 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Identification of molecules that regulate the sensitivity of EZH2 inhibitor in neuroblastoma2018
- Author(s)
  Yuki Endo, Hisanori Takenobu, Ryuichi Sugino, Masayuki Haruta, Kyosuke Mukae, Shunpei Satoh, Yoshitaka Shinno, Mariko Hasegawa, Ryu Okada, Yutaka Katai, Masaki Nio, Miki Ohira, Takehiko Kamijo
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications2018
- Author(s)
  Zhenghao Li, Hisanori Takenobu, Amallia Nuggetsiana Setyawati, Nobuhiro Akita, Masayuki Haruta, Shunpei Satoh, Yoshitaka Shinno, Koji Chikaraishi, Kyosuke Mukae, Jesmin Akter, Ryuichi P. Sugino, Atsuko Nakazawa, Akira Nakagawara, Hiroyuki Aburatani, Miki Ohira, Takehiko Kamijo
- Organizer
  Advanced Neuroblastoma Research 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Polycomb molecule L3MBTL2 suppresses apoptotic cell death cooperating with BMI1 in neuroblastoma2018
- Author(s)
  Ryu Okada, Hisanori Takenobu, Miki Ohira, Ryuichi Sugino, Koji Chikaraishi, Nobuhiro Akita, Masayuki Haruta, Kyosuke Mukae, Yuki Endo, Shunpei Satoh, Yutaka Katai, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Sphere specific transcription factor CDX1 has dual functions for regulating stemness of neuroblastoma2017
- Author(s)
  Hisanori Takenobu, Ryuichi Sugino, Miki Ohira, Koji Chikaraishi, Kyosuke Mukae, Masayuki Haruta, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Effect of CFC1 on cancer cell stemness in neuroblastoma2017
- Author(s)
  Koji Chikaraishi, Hisanori Takenobu, Ryuichi Sugino, Kyosuke Mukae, Jesmin Akter, Masayuki Haruta, Masafumi Kurosumi, Takaho Endo, Haruhiko Koseki, Naoki Shimojo, Miki Ohira, Takehiko Kamijo
- Organizer
  第59回日本小児血液がん学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications2017
- Author(s)
  Hisanori Takenobu, Zhenghao Li, Masayuki Haruta, Shunpei Satoh, Yoshitaka Shinno, Kyosuke Mukae, Jesmin Akter, Ryuichi Sugino, Akira Nakagawara, Hiroyuki Aburatani, Miki Ohira, Takehiko Kamijo
- Organizer
  The 3rd Asia-Pacific International Symposium of Neuroblastoma
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications2017
- Author(s)
  Zhenghao Li, Hisanori Takenobu, Masayuki Haruta, Shunpei Satoh, Yoshitaka Shinno, Kyosuke Mukae, Jesmin Akter, Ryuichi Sugino, Akira Nakagawara, Hiroyuki Aburatani, Miki Ohira, Takehiko Kamijo
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] CFC1 regulates cancer stemness phenotypes in neuroblastoma via Activin signaling suppression2017
- Author(s)
  Koji Chikaraishi, Hisanori Takenobu, Ryuichi Sugino, Kyosuke Mukae, Masayuki Haruta, Masafumi Kurosumi, Yoshitaka Shinno, Akter Jesmin, A Takaho Endo, Haruhiko Koseki, Miki Ohira, Takehiko Kamijo
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Sphere specific transcription factor CDX1 regulates stemness of neuroblastoma2017
- Author(s)
  Hisanori Takenobu, Ryuichi Sugino, Miki Ohira, Koji Chikaraishi, Kyosuke Mukae, Yuki Endo, Sultana Parvin, Ryu Okada, Yutaka Katai, Masayuki Haruta, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  第59回日本小児血液がん学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] CRISPR/Cas9-based knockout of the chromatin remodeling factor ATRX and its effect in neuroblastoma (NB) cells2017
- Author(s)
  Jesmin Akter, Yutaka Katai, Hisanori Takenobu, Masayuki Haruta, Parvin Sultana, Kyosuke Mukae, Ryuichi Sugino, Miki Ohira, Takehiko Kamijo
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Characterization of cell type by DNA methylation pattern using principal component analysis-based approach2017
- Author(s)
  Ryuichi Sugino, Miki Ohira, Satoshi Yamashita, Hisanori Takenobu, Junya Toguchida, Toshikazu Ushijima, Takehiko Kamijo
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications2017
- Author(s)
  Hisanori Takenobu, Zhenghao Li, Amallia Nuggetsiana Setyawati, Nobuhiro Akita, Masayuki Haruta, Shunpei Satoh, Yoshitaka Shinno, Koji Chikaraishi, Kyosuke Mukae, Jesmin Akter, Yuki Endo, Ryuichi P. Sugino, Akira Nakagawara, Hiroyuki Aburatani, Miki Ohira, Takehiko Kamijo
- Organizer
  第59回日本小児血液がん学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] 神経芽腫幹細胞を制御する新規シグナル経路の解析2016
- Author(s)
  Hisanori Takenobu, Miki Ohira, Koji Chikaraishi, Kyosuke Mukae, Nobuhiro Akita, Masayuki Haruta, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] ヒトiPS細胞を用いた神経芽腫発がんモデル2016
- Author(s)
  Takenobu H, Sugino R, Ohira M, Yamashita S, Toguchida J, Kamijo T
- Organizer
  第58回日本小児血液がん学会学術集会
- Place of Presentation
  品川
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] iPS細胞から神経堤細胞への分化における統合解析2016
- Author(s)
  Sugino R, Ohira M, Yamashita S, Takenobu H, Toguchida J, Ushijima T, Kamijo T
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] CDX1 regulates cancer stemness pathway in neuroblastoma, CDX1 regulates cancer stemness pathway in neuroblastoma2016
- Author(s)
  Hisanori Takenobu, Miki Ohira, Koji Chikaraishi, Nobuhiro Akita, Yohko Yamaguchi, Masayuki Haruta, Akira Nakagawara, Manabu Nakayama, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  国際神経芽腫学会 (ANR2016)
- Place of Presentation
  ケアンズ (オーストラリア)
- Year and Date
  2016-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] EZH2による神経芽腫の分化抑制2016
- Author(s)
  Li Z, Setyawati AN, Takenobu H, Akita N, Haruta M, Chikaraishi K, Mukae K, Akter J, Sugino R, Ohira M, Kamijo K
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] CFC-1遺伝子は神経芽腫細胞の幹細胞化制御因子である2016
- Author(s)
  Chikaraishi K, Takenobu H, Mukae K, Sugino R, Ohira M, Koseki H, Kamijo T
- Organizer
  第58回日本小児血液がん学会学術集会
- Place of Presentation
  品川
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-16K10051
[Presentation] Polycomb group protein BMI1 protects neuroblastoma cells from DNA damage-induced apoptotic death in cooperation with L3MBTL22016
- Author(s)
  N. Akita, H. Takenobu, K. Chikaraishi, M. Ohira, T. Kamijo
- Organizer
  第107回米国癌学会総会
- Place of Presentation
  米国ニューオーリンズ
- Year and Date
  2016-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] 神経芽腫のがん幹細胞性を制御する経路の探索2015
- Author(s)
  竹信尚典, 大平美紀, 力石浩志, 秋田直洋, 山口 (末永) 陽子, 春田雅之, 古関明彦, 上條岳彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Neuroblastoma sphere specific gene regulates stemness pathway for cancer stem cells2015
- Author(s)
  H. Takenobu, M. Ohira, K. Chikaraishi, N. Akita, Y. Yamaguchi, M. Haruta, H. Koseki, T. Kamijo
- Organizer
  神経芽腫アジアパシフィックシンポジウム2015台湾
- Place of Presentation
  台湾台北市
- Year and Date
  2015-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] ポリコーム群タンパク質 L3MBTL2 はBMI1 と協調的に腫瘍細胞死を抑制する2015
- Author(s)
  力石浩志, 秋田直洋, 春田雅之, 大平美紀, 竹信尚典, 古関明彦, 上條岳彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] 神経芽腫のがん幹細胞性を制御するシグナル経路2015
- Author(s)
  竹信尚典, 大平美紀, 上條岳彦
- Organizer
  第54回日本小児血液がん学会学術集会
- Place of Presentation
  山梨県甲府市
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] FUNCTIONAL P53 INACTIVATION IN NEUROBLASTOMA: NOVEL 1P TUMOR SUPPRESSOR DMAP1 REGULATES MYCN/ATM/P53 PATHWAY2013
- Author(s)
  Yohko Yamaguchi, Hisanori Takenobu, Osamu Shimozato, Miki Ohira, Akira Nakagawara and Takehiko Kamijo
- Organizer
  p63/p73 Workshop
- Place of Presentation
  Chiba, Japan
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] Tumor sphere specific transcription factor regulates stem cell-related genes in neuroblastoma2013
- Author(s)
  Hisanori Takenobu1, Osamu Shimozato1, Haruhiko Koseki, and Takehiko Kamijo
- Organizer
  Japan-Taiwan Neuroblastoma Meeting
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] Functional analysis of a novel 1p tumor suppressor DMAP12012
- Author(s)
  Yohko Yamaguchi, Hisanori Takenobu, Sayaka Yoshida, Nobuhiro Akita, Miki Ohira, Atsuko Nakazawa, Akira Nakagawara, Takehiko Kamijo
- Organizer
  Advances of Neuroblastoma Research 2012
- Place of Presentation
  トロント(カナダ)
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] MYCN-DEPENDENT ONCOGENIC BMI1 INDUCTION IN NEUROBLA STOMA AND FIBROBLASTS2012
- Author(s)
  Hidemasa Ochiai, Hisanori Takenobu, Yohko Yamaguchi, Nobuhiro Akita, Takehiko Kamijo
- Organizer
  第7回 International Society of Paediatric Oncology (SIOP) Asia 2012
- Place of Presentation
  ジョクジャカルタ(インドネシア)
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] ANALYSIS OF MYCN-DEPENDENT APOPTOTIC CELL DEATH PATHWAY2012
- Author(s)
  Yohko Yamaguchi, Hisanori Takenobu, Nobuhiro Akita, Takehiko Kamijo
- Organizer
  第44回International Society of Paediatric Oncology (SIOP) 2012
- Place of Presentation
  ロンドン(イギリス)
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] 神経芽腫スフェア形成に関わるキー分子の探索2012
- Author(s)
  竹信尚典, 下里修, 秋田直洋, 山口陽子, 上原悠, 藁谷美雪, 吉田早哉香, 中川原章, 上條岳彦
- Organizer
  第54回日本小児血液がん学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2012-11-30
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] CD133 suppresses neuro-blastoma cell differentiation via signal pathway modification,2012
- Author(s)
  竹信尚典
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Tumor sphere specific CD133 regulation in neuroblastoma2012
- Author(s)
  Hisanori Takenobu, Osamu Shimozato, Nobuhiro Akita, Yohko Yamaguchi, Haruka Uehara, Miyuki Waraya, Sayaka Yoshida, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Functional analysis of a novel 1p tumor suppressor DMAP12012
- Author(s)
  Yohko Yamaguchi, Hisanori Takenobu, Sayaka Yoshida, Nobuhiro Akita, Miki Ohira, Akira Nakagawara, Takehiko Kamijo
- Organizer
  Japan-China Symposium on Cancer Research 2012
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] 1番染色体短腕に位置するがん抑制遺伝子DMAP1の転写制御機構の解析2012
- Author(s)
  Sayaka Yoshida, Yohko Yamaguchi, Hisanori Takenobu, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Sphere formation produces multi-drug resistance in humancolon cancer cells resulting via histone modification of ABCB1promoter2012
- Author(s)
  Osamu Shimozato, Haruka Uehara, Miyuki Waraya, Hisanori Takenobu, Akira Nakagawara , Takehiko Kamijo
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Tumor sphere specific CD133 regulation in neuroblastoma2012
- Author(s)
  Hisanori Takenobu, Osamu Shimozato, Nobuhiro Akita, Yohko Yamaguchi, Haruka Uehara, Miyuki Waraya, Sayaka Yoshida, Akira Nakagawara, Takehiko Kamijo
- Organizer
  Advances of Neuroblastoma Research 2012
- Place of Presentation
  トロント(カナダ)
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] CD133 suppresses neuroblastoma cell differentiation via signal pathway modification2012
- Author(s)
  Hisanori Takenobu
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] BMI1 regulates neuroblastoma apoptotic cell death and differentiation2012
- Author(s)
  Nobuhiro Akita, Hisanori Takenobu, Atsuko Nakazawa, Hidemasa Ochiai, Akira Nakagawara, Takehiko Kamijo
- Organizer
  Advances of Neuroblastoma Research 2012
- Place of Presentation
  トロント(カナダ)
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] BMI1 regulates neuroblastoma apoptotic cell death and differentiation2012
- Author(s)
  Nobuhiro Akita, Hisanori Takenobu, Hidemasa Ochiai, Atsuko Nakazawa, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Tumor sphere specific CD 133regulation in neuroblastoma2012
- Author(s)
  竹信尚典,下里修,秋田直洋,山口陽子,上原悠,藁谷美雪,吉田早哉香,落合秀匡,大平美紀,中川原章,上條岳彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Polycomb group protein BMI1 prevents neuroblastoma cells from DNA-damage-induced apoptotic cell death2012
- Author(s)
  Nobuhiro Akita, Hisanori Takenobu, Hidemasa Ochiai, Atsuko Nakazawa, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Tumor sphere specific CD133 regulation in neuroblastoma2012
- Author(s)
  竹信尚典,下里修,秋田直洋,山口陽子,上原悠,藁谷美雪,吉田早哉香,落合秀匡,大平美紀,中川原章,上條岳彦
- Organizer
  Advances of Neuroblastoma Research 2012
- Place of Presentation
  トロント
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Identification of key molecules that regulate neuroblastoma sphere formation2012
- Author(s)
  竹信尚典,下里修,秋田直洋,山口陽子,上原悠,藁谷美雪,吉田早哉香,落合秀匡,大平美紀,中川原章,上條岳彦
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] DMAP1 acts as a tumor suppressor through ATM activation in neuroblastoma various regulation mechanisms of ATM family kinases and their tissue- or species-specific roles2012
- Author(s)
  Yohko Yamaguchi, Hisanori Takenobu, Sayaka Yoshida, Nobuhiro Akita, Miki Ohira, Atsuko Nakazawa, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] BMI1 regulates neuroblastoma apoptotic cell death and differentiation2011
- Author(s)
  Nobuhiro Akita, Hisanori Takenobu, Hiroki Nagase, Takehiko Kamijo
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] BMI1発現抑制による難治性神経芽腫の細胞死・分化誘導療法の開発2011
- Author(s)
  秋田直洋, 竹信尚典, 落合秀匡, 永瀬浩喜, 中川原章, 上條岳彦
- Organizer
  第53回日本小児血液・がん学会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] MDM2 impairs NOXA transcription and affects apoptotic cell death in a p53/p73-dependent manner in neuroblastoma2011
- Author(s)
  Yun Shi, Hisanori Takenobu, Kenji Kurata, Yohko Yamaguchi, Ken-ichi Koike, Akira Nakagawara, Takehiko Kamijo
- Organizer
  The 5 th International p63/p73 Workshop
- Place of Presentation
  リヨン(フランス)
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] 神経芽腫/脳腫瘍スフェア特異的なCD133発現調節機構2011
- Author(s)
  竹信尚典,下里修,秋田直洋,山口陽子,吉田早哉香,落合秀匡,大平美紀,中川原章,上條岳彦
- Organizer
  第53回日本小児血液・がん学会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] 幹細胞マーカーCD133は細胞内シグナル活性化を介して神経芽腫の増殖と分化を制御する2011
- Author(s)
  竹信尚典,上條岳彦
- Organizer
  第116回小児血液腫瘍懇話会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Bmi1 regulates cell fate via tumor suppressor WWOX repression in small cell lung cancer cells2011
- Author(s)
  Masaki Kimura, Hisanori Takenobu, Nobuhiro Akita, Osamu Shimozato, Hideki Kimura, Akira Nakagawara, Takehiko Kamijo
- Organizer
  AACR 102nd Annual Meeting 2011
- Place of Presentation
  フロリダ(アメリカ)
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] Acquired multi-drug resistance in human colon cancer cells by sphere formation2011
- Author(s)
  Kumiko Nakashima, Osamu Shimozato, Hisanori Takenobu, Toshinori Ozaki, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] CD133 plays roles in keeping the undifferentiated status of human colon cancer cells via PI3K/AKT activation2011
- Author(s)
  竹信尚典,下里修,秋田直洋,山口陽子,吉田早哉香,中川原章,上條岳彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] DMAP1 works as a novel 1p tumor suppressor via ATM/p53 activation2011
- Author(s)
  Yohko Yamaguchi, Hisanori Takenobu, Sayaka Yoshida, Miki Ohira, Atsushi Iwama, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] CD133 regulates signal transduction pathways and prevents differentiation via RET suppression in neuroblastoma cells2010
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 山口陽子, 大平美紀, 中川原章, 上條岳彦
- Organizer
  Advances of Neurobiastoma Research 2010
- Place of Presentation
  ストックホルム
- Year and Date
  2010-06-22
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] 幹細胞マーカーCD133はRETの発現抑制を介して神経芽腫の分化を制御する2010
- Author(s)
  竹信尚典, 下里修, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第14回神経芽腫研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] CD133 regulates neuroblastoma stemness via p38MAPK and PI3K/Akt activation2010
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 山口陽子, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] CD133はシグナル経路依存的に受容体RETの転写抑制を引き起こし、神経芽腫の増殖と分化を制御する2010
- Author(s)
  竹信尚典, 下里修, 山口陽子, 秋田直洋, 吉田早哉香, 落合秀匡, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第26回日本小児がん学会
- Place of Presentation
  大阪
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] CD133 regulates signal transduction pathways and prevents differentiation via RET suppression in neuroblastoma cells2010
- Author(s)
  竹信尚典,下里修,落合秀匡,山口陽子,大平美紀,中川原章,上條岳彦
- Organizer
  Advances of Neuroblastoma Research 2010
- Place of Presentation
  ストックホルム
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] CD133はシグナル経路依存的に受容体RETの転写抑制を引き起こし、神経芽腫の増殖と分化を制御する2010
- Author(s)
  竹信尚典,下里修,山口陽子,秋田直洋,吉田早哉香,落合秀匡,大平美紀,中川原章,上條岳彦
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] CD133 regulates neuroblastoma stemness via p38MAPK and PI3K/Akt activation2010
- Author(s)
  竹信尚典,下里修,落合秀匡,山口陽子,大平美紀,中川原章,上條岳彦
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22791017
[Presentation] CD133 is epigenetically regulated and regulates differentiation via RET in neuroblastoma cells2009
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 木村昌樹, 山口陽子, 松下せりな, 中島久美子, 中川原章, 上條岳彦
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] MYCN target gene CD133 regulates proliferation and sternness of neuroblastoma2009
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 木村昌樹, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] エピジェネティックな制御を受ける幹細胞マーカーCD133はRETの発現制御を介して神経芽腫の分化を制御する2009
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 木村昌樹, 山口陽子, 松下せりな, 中島久美子, 中川原章, 上條岳彦
- Organizer
  第25回日本小児がん学会
- Place of Presentation
  浦安
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] エピジェネティックな制御を受ける幹細胞マーカーCD133はRETの発現制御を介して神経芽腫の分化を制御する2009
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 木村昌樹, 山口陽子, 松下せりな, 中島久美子, 中川原章, 上條岳彦
- Organizer
  第25回白本小児がん学会
- Place of Presentation
  浦安
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] MYCNの新規な標的遺伝子であるCD133は神経芽腫の増殖と幹細胞性を制御する2009
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 山口陽子, 松下せりな, 木村昌樹, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第104回小児血液腫瘍懇話会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] Stem cell marker CD133 is a novel MYCN target and regulates aggressiveness in neuroblastoma2008
- Author(s)
  竹信尚典, 下里修, 木村昌樹, 落合秀匡, 大平美紀, 中川原章, 上條岳彦
- Organizer
  2008国際神経芽腫学会(ANR 2008)
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] MYCNは幹細胞マーカーCD133の転写を制御する2008
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 山口陽子, 松下せりな, 木村昌樹, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第31回日本分子生物学会年会, 第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] Stem cell marker CD133 is a novel MYCN target and regulates aggressiveness in neuroblastoma2008
- Author(s)
  Takenobu H, Shimozato O, Kimura M, Ochiai H, Ohira M, Nakagawara A, Kamijo T
- Organizer
  2008 国際神経芽腫学会 (ANR 2008)
- Place of Presentation
  千葉
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] MYCN target gene CD133 regulates proliferation and sternness of neuroblastoma2008
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 木村昌樹, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  千葉
- Year and Date
  2008-11-16
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] MYCNは幹細胞マーカーCD133の転写を制御する2008
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 山口陽子, 松下せりな, 木村昌樹, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第31回日本分子生物学会年会, 第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] MYCNの新規転写ターゲットCD133は神経芽腫の増殖と幹細胞性を制御する2008
- Author(s)
  竹信尚典, 下里修, 落合秀匡, 木村昌樹, 松下せりな, 山口陽子, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第24回日本小児がん学会総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] Effects of CD133 on steMness-related characters of neuroblastoma cells2007
- Author(s)
  竹信尚典, 下里修, 木村昌樹, 中川原章, 上條岳彦
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] 幹細胞マーカーCD133が神経芽腫のstemnessに及ぼす役割2007
- Author(s)
  竹信尚典, 下里修, 木村昌樹, 大平美紀, 好田忠行, 中川原章, 上條岳彦
- Organizer
  第23回日本小児がん学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] Effects of CD133 on stemness-related characters of neuroblastoma cells2007
- Author(s)
  竹信尚典, 下里修, 木村昌樹, 中川原章, 上條岳彦
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] 幹細胞マーカーCD133が神経芽腫のstemnessに及ぼす役割2007
- Author(s)
  竹信尚典, 下里修, 木村昌樹, 大平美紀, 好田忠行, 中川原章, 上條岳彦
- Organizer
  第23回日本小児がん学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-12-16
- Data Source
  KAKENHI-PROJECT-19790274
[Presentation] Effects of hypoxia on the expressions of differentiation- and stem cell-related genes in human lung carcinoma A549 cells.2006
- Author(s)
  Takenaga K, Koshikawa N, Mochizuki S, Takenobu H, Ohira M.
- Organizer
  The 65th Annual Meeting of The Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590280
[Presentation] Hypoxia stimulates dedifferentiation and metastatic potential of human lung carcinoma cells.2006
- Author(s)
  Takenaga K, Koshikawa N, Mochizuki S, Takenobu H, Ohira M, Hori H, Nagasawa H, Uto Y.
- Organizer
  The 4th Annual Meeting of The Japanese Association of Cancer and Hypoxia Research
- Place of Presentation
  Kyoto
- Year and Date
  2006-11-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590280
[Presentation] ヒストン脱メチル化酵素JHDM1Bは大腸がんスフェア細胞のABCB1依存的な薬剤耐性獲得を阻害する
- Author(s)
  池田英里子, 下里修, 早田浩明, 竹信尚典, 上條岳彦, 永瀬浩喜, 尾崎俊文
- Organizer
  日本癌学会
- Place of Presentation
  横浜市西区
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Tumor Sphere Specific Transcription Factor CDX1 Regulates Stem Cell-Related Gene Expression and Aggressiveness in Neuroblastoma
- Author(s)
  Hisanori Takenobu, Osamu Shimozato, Yu-ichi Fujimura, Nobuhiro Akita, Yohko Yamaguchi, Haruka Uehara, Miyuki Waraya, Eriko Ikeda, Akira Nakagawara, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  Advanced Neuroblastoma Research
- Place of Presentation
  ドイツ, ケルン市
- Year and Date
  2014-05-14 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] ポリコーム群タンパク質 L3MBTL2, BMI1 を標的とした新規治療法の開発
- Author(s)
  力石浩志, 秋田直洋, 春田雅之, 大平美紀, 竹信尚典, 古関明彦, 上條岳彦
- Organizer
  第54回日本小児血液がん学会学術集会
- Place of Presentation
  山梨県甲府市
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Tumor Sphere Specific Transcription Factor CDX1 Regulates Stem Cell-Related Gene Expression and Aggressiveness in Neuroblastoma
- Author(s)
  Hisanori Takenobu, Osamu Shimozato, Yu-ichi Fujimura, Nobuhiro Akita, Yohko Yamaguchi, Haruka Uehara, Miyuki Waraya, Eriko Ikeda, Akira Nakagawara, Haruhiko Koseki, Takehiko Kamijo
- Organizer
  Advanced Neuroblastoma Research
- Place of Presentation
  ドイツ, ケルン市
- Year and Date
  2014-05-11 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] ヒストン脱メチル化酵素JHDM1Bは大腸がんスフェア細胞のABCB1依存的な薬剤耐性獲得を阻害する
- Author(s)
  池田英里子, 下里修, 早田浩明, 竹信尚典, 上條岳彦, 永瀬浩喜, 尾崎俊文
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] ポリコーム PRC2 複合体 EZH2 の異常ヒストン修飾による神経芽腫発がん
- Author(s)
  竹信尚典, Amallia Nuggetsiana Setyawati, 秋田直洋, 上條岳彦
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] 神経芽腫スフェア形成に関わる転写因子の標的探索
- Author(s)
  竹信尚典, 下里修, 秋田直洋, 山口陽子, 上原悠, 藁谷美雪, 池田英里子, 中川原章, 上條岳彦
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] MYCN/ATM/p53経路を制御する1pがん抑制遺伝子DMAP1
- Author(s)
  上條岳彦, 大平美紀, 竹信尚典, 中川原章, 山口（末永）陽子
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] 神経芽腫スフェア特異的に発現する転写因子CDX1は細胞の幹細胞性を制御する
- Author(s)
  竹信尚典, 下里修, 藤村雄一, 秋田直洋, 山口陽子, 力石浩志, 池田英里子, 田川雅敏, 中川原章, 古関明彦, 上條岳彦
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] 大腸がん由来spheroid細胞はエピゲノム的制御によるABCB1遺伝子の発現上昇によって多剤耐性を獲得する
- Author(s)
  上原悠, 下里修, 藁谷美雪, 早田浩明, 崔星, 竹信尚典、上條岳彦
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Novel 1p Tumor Suppressor DMAP1 Regulates MYCN/ATM/p53 Pathway
- Author(s)
  Yohko Yamaguchi-Suenaga, Hisanori Takenobu, Miki Ohira, Nobuhiro Akita, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第56回日本小児血液・がん学会学術集会
- Place of Presentation
  岡山コンベンションセンター(岡山市北区)
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] Novel 1p Tumor Suppressor DMAP1 Regulates MYCN/ATM/p53 Pathway
- Author(s)
  Takehiko Kamijo, Yohko Yamaguchi, Hisanori Takenobu, Miki Ohira, Atsuko Nakazawa, Akira Nakagawara
- Organizer
  Advanced Neuroblastoma Research
- Place of Presentation
  ドイツ, ケルン市
- Year and Date
  2014-05-11 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Tumor sphere specific transcription factor regulates stem cell-related genes in neuroblastoma
- Author(s)
  竹信尚典, 下里修, 古関明彦, 上條岳彦
- Organizer
  第1回日本・台湾神経芽腫シンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Novel 1p Tumor Suppressor DMAP1 Regulates MYCN/ATM/p53 Pathway
- Author(s)
  Yohko Yamaguchi-Suenaga, Hisanori Takenobu, Miki Ohira, Nobuhiro Akita, Akira Nakagawara, Takehiko Kamijo
- Organizer
  日本小児血液がん学会
- Place of Presentation
  岡山市北区
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] 神経芽腫スフェア特異的に発現する転写因子CDX1は細胞の幹細胞性を制御する
- Author(s)
  竹信尚典, 下里修, 藤村雄一, 秋田直洋, 山口陽子, 力石浩志, 池田英里子, 田川雅敏, 中川原章, 古関明彦, 上條岳彦
- Organizer
  日本癌学会
- Place of Presentation
  横浜市西区
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] 膜結合型チロシン脱リン酸化酵素PTPRKによるチロシン脱リン酸化はがん幹細胞マーカーCD133の機構を負に制御する
- Author(s)
  下里修, 早田浩明, 藁谷美雪, 上原悠, 竹信尚典, 崔星, 上條岳彦
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] MYCN/ATM/p53 経路を制御する新規がん抑制遺伝子 DMAP1
- Author(s)
  山口陽子, 竹信尚典, 大平美紀, 中澤温子, 吉田早哉香, 秋田直洋, 下里修, 岩間厚志, 中川原章, 上條岳彦
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Identification of neuroblastoma stemness-regulating pathway using tumor sphere
- Author(s)
  Hisanori Takenobu, Osamu Shimozato, Yu-ichi Fujimura, Nobuhiro Akita, Yohko Yamaguchi, Koji Chikaraishi, Eriko Ikeda, Masatoshi Tagawa, Akira Nakagawara, Takehiko Kamijo
- Organizer
  日本小児血液がん学会
- Place of Presentation
  岡山市北区
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Novel 1p Tumor Suppressor DMAP1 Regulates MYCN/ATM/p53 Pathway
- Author(s)
  Takehiko Kamijo, Yohko Yamaguchi, Hisanori Takenobu, Miki Ohira, Atsuko Nakazawa, Akira Nakagawara
- Organizer
  Advanced Neuroblastoma Research
- Place of Presentation
  ドイツ, ケルン市
- Year and Date
  2014-05-14 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] 受容体型蛋白質チロシン脱リン酸化酵素PTPRKはCD133を脱リン酸化し, その下流に繋がるAKT経路の活性化を鎮静化する
- Author(s)
  下里修, 早田浩明, 池田英里子, 竹信尚典, 上條岳彦, 永瀬浩喜, 尾崎俊文
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] 膜結合型チロシン脱リン酸化酵素PTPRKによるチロシン脱リン酸化はがん幹細胞マーカーCD133のAKT/b-catenin経路を介した発がん機構を負に制御する
- Author(s)
  藁谷美雪, 下里修, 早田浩明, 上原悠、竹信尚典, 崔星, 上條岳彦
- Organizer
  第36回分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] MYCN/ATM/p53経路を制御する1pがん抑制遺伝子DMAP1
- Author(s)
  上條岳彦, 大平美紀, 竹信尚典, 中川原章, 山口（末永）陽子
- Organizer
  日本癌学会
- Place of Presentation
  横浜市西区
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] 受容体型蛋白質チロシン脱リン酸化酵素PTPRKはCD133を脱リン酸化し, その下流に繋がるAKT経路の活性化を鎮静化する
- Author(s)
  下里修, 早田浩明, 池田英里子, 竹信尚典, 上條岳彦, 永瀬浩喜, 尾崎俊文
- Organizer
  日本癌学会
- Place of Presentation
  横浜市西区
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Identification of neuroblastoma stemness-regulating pathway using tumor sphere
- Author(s)
  Hisanori Takenobu, Osamu Shimozato, Yu-ichi Fujimura, Nobuhiro Akita, Yohko Yamaguchi, Koji Chikaraishi, Eriko Ikeda, Masatoshi Tagawa, Akira Nakagawara, Takehiko Kamijo
- Organizer
  第56回日本小児血液・がん学会学術集会
- Place of Presentation
  岡山コンベンションセンター(岡山市北区)
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-24390269
[Presentation] 神経芽腫スフェア特異的な転写因子による幹細胞関連遺伝子の発現制御
- Author(s)
  竹信尚典, 下里修, 秋田直洋, 山口陽子, 上原悠, 藁谷美雪, 池田英里子, 中川原章, 上條岳彦
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25461614
[Presentation] Functional p53 inactivation in neuroblastoma: novel 1p tumor suppressor DMAP1 regulates MYCN/ATM/p53 pathway
- Author(s)
  山口陽子, 竹信尚典, 下里修, 大平美紀, 中川原章, 上條岳彦
- Organizer
  第6回国際p63/p73ワークショップ
- Place of Presentation
  木更津
- Data Source
  KAKENHI-PROJECT-25461614

1. KAMIJO Takehiko (90262708)

# of Collaborated Projects: 3 results

# of Collaborated Products: 64 results
2. OHIRA Miki (20311384)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAKAGAWARA Akira (50117181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. OZAKI Toshinori (40260252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KEIZO Takenaga (80260256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. KOSHIKAWA Nobuko (90260249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 田尻達郎 (80304806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 吉田英生 (60210712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 春田雅之 (80392190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 迎恭輔 (60793974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. 小貫律子 (40863022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 市川美紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
13. 早田浩明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 下里修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. AKTER JESMIN

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 中村洋子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takenobu Hisanori 竹信 尚典

TAKENOBU Hisanori 竹信 尚典

Research Projects

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Elucidating epigenetic modifications induced by oncogenic transcription factor CDXs in cancer cellsPrincipal Investigator

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Discover for the second-hit gene regions using comprehensive gene destruction in neuroblastoma carcinogenesisPrincipal Investigator

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Single cell screening of molecular target in using malignant neuroblastoma animal modelPrincipal Investigator

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A novel therapeutic targeting of CD133 transcription in malignant neuroblastomaPrincipal Investigator

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Development of cancer stem cell-targeted therapy by study of tumor sphere formation mechanism using comprehensive and genetic approach

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Identification of tumor stem-specific transcription factor in neuroblastoma spherePrincipal Investigator

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Identification and functional analysis of novel stem cell markers in neuronal-related cellsPrincipal Investigator

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Analysis of the effects of tumor hypoxia on dynamics of cancer stem cells

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Identification of Cancer Stem Cells and Its Clinical Application for Treating Aggressive Neuroblastomas

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[Journal Article] Platelet-to-Lymphocyte Ratio Predicts the Efficacy of Pembrolizumab in Patients With Urothelial Carcinoma.2022

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[Journal Article] Polycomb EZH1 regulates cell cycle/5‐fluorouracil sensitivity of neuroblastoma cells in concert with MYCN2022

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[Journal Article] The PRC2 molecule EED is a target of epigenetic therapy for neuroblastoma2022

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[Journal Article] Loss of p53 suppresses replication stress-induced DNA damage in ATRX-deficient neuroblastoma2021

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[Journal Article] EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications2018

Takenobu Hisanori 竹信尚典

TAKENOBU Hisanori 竹信尚典