Higa Kazunari 比嘉一成

… Alternative Names

HIGA Kazunari 比嘉一成

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Researcher Number	60398782
Other IDs
Affiliation (Current)	2025: 東京歯科大学, 歯学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2025: 東京歯科大学, 歯学部, 講師 2013 – 2018: 東京歯科大学, 歯学部, 助教 2012: 慶應義塾大学, 医学部, 研究員 2009 – 2011: Keio University, 医学部, 共同研究員 2009: 慶応義塾大学, 医学部 2005 – 2006: 東京歯科大学, 歯学部, 客員講師
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology Except Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related / Basic Section 57060:Surgical dentistry-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator ニッチ / 角膜上皮幹細胞 / オルガノイド / 角膜輪部上皮 / 角膜上皮 / 細胞治療 / 幹細胞ニッシェ / スフェロイド / corneal limbal niche / インターラクション … More / siRNA / 角膜上皮前駆細胞 / ニッシェ / N-cadherin … More Except Principal Investigator 角膜移植 / 前房関連角膜内皮症 / ニコチナミドモノヌクレオチド / 難治性水疱性角膜症 / 細胞老化 / 角膜内皮細胞 / 前駆細胞 / 環境 / 虹彩萎縮 / 治療薬 / 前房環境 / 咀嚼筋腱・腱膜過形成症 / 発生 / 筋内腱 / メタボローム解析 / 水疱性角膜症 / 前房水 / 保存 / 間葉系幹細胞 / 羊膜 / Progenitor Cells / Immunohistochemistry / Regenerative Medicine / Cytokeratin / Cell Culture / Hypoxia / Stem Cells / Corneal epithelium / 免疫染色 / 再生医療 / サイトケラチン / 細胞培養 / 低酸素 / 幹細胞 / 角膜上皮細胞 / 創傷治癒 / 神経栄養欠乏性角膜上皮欠損 / 角膜上皮 / 遷延性角膜上皮欠損 Less

角膜オルガノイドにおける角膜輪部幹細胞ーニッチメカニズムの解明Principal Investigator
- Principal Investigator
  
  比嘉一成
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tokyo Dental College
咀嚼筋腱・腱膜過形成症の病因解明に向けた基礎研究～“筋内腱”発生機序の探索～
- Principal Investigator
  
  山本将仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokai University
  Tokyo Dental College
Establishment of experimental basis to improve the prognosis of corneal transplantation in treating bullous keratoplasty due to pathological aqueous humor.
- Principal Investigator
  
  山口剛史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tokyo Dental College
Constrction and analysis of limbal niche in the corneal organoidsPrincipal Investigator
- Principal Investigator
  
  Higa Kazunari
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tokyo Dental College
Proposal of a novel therapy for bullous keratopathy based on human-derived multiomics analysis
- Principal Investigator
  
  Takefumi Yamaguchi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tokyo Dental College
Establishment of long-term culture method of limbal organoids using methylcellulose.Principal Investigator
- Principal Investigator
  
  Higa Kazunari
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tokyo Dental College
Spheroidal cultivation of the human limbal epithelial niche from small limbal tissue.Principal Investigator
- Principal Investigator
  
  HIGA KAZUNARI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Dental College
The relationship between the amniotic and mesenchymal stem cell, the its effect and preservation
- Principal Investigator
  
  Shimazaki Jun
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Dental College
Analysis of limbal epithelial tiny cells contact with limbal niche like cellsPrincipal Investigator
- Principal Investigator
  
  HIGA Kazunari
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Dental College
  Keio University
Role of N-cadherin in the niche of corneal limbal ephtheliumPrincipal Investigator
- Principal Investigator
  
  HIGA Kazunari
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Wound healing model of corneal epithelium using stenless-ring.
- Principal Investigator
  
  SHIMMURA Machiko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Dental College
Hypoxic culture in the isolation of corneal stem cells
- Principal Investigator
  
  SHIMMURA Shigeto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Dental Collage

[Journal Article] Donor-Related Risk Factors for Graft Decompensation Following Descemet's Stripping Automated Endothelial Keratoplasty2022
- Author(s)
  Nishisako S, Yamaguchi T, Hirayama M, Higa K, Aoki D, Sasaki C, Noma H, Shimazaki J.
- Journal Title
  
  Front Med
  
  Volume: 4 Pages: 810536-810536
- DOI
  10.3389/fmed.2022.810536
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21663
[Journal Article] Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty2021
- Author(s)
  Yuki Kusano, Takefumi Yamaguchi, Sota Nishisako, Takehiro Matsumura, Masaki Fukui, Kazunari Higa, Toshihiro Inoue, Jun Shimazaki
- Journal Title
  
  Translational Visual Science Technology
  
  Volume: 10 Issue: 11 Pages: 12-12
- DOI
  10.1167/tvst.10.11.12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21663
[Journal Article] Elevated Cytokine Levels in Aqueous Humor Are Associated with Peripheral Anterior Synechiae after Penetrating Keratoplasty2021
- Author(s)
  Yuki Kusano, Takefumi Yamaguchi, Sota Nishisako, Takehiro Matsumura, Masaki Fukui, Kazunari Higa, Toshihiro Inoue, Jun Shimazaki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 22 Pages: 12268-12268
- DOI
  10.3390/ijms222212268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21663
[Journal Article] Pathological processes in aqueous humor due to iris atrophy predispose to early corneal graft failure in humans and mice2020
- Author(s)
  Yamaguchi Takefumi、Higa Kazunari、Yagi-Yaguchi Yukari、Ueda Koji、Noma Hisashi、Shibata Shinsuke、Nagai Toshihiro、Tomida Daisuke、Yasu-Mimura Ririko、Ibrahim Osama、Matoba Ryo、Tsubota Kazuo、Hamrah Pedram、Yamada Jun、Kanekura Kohsuke、Shimazaki Jun
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 20 Pages: 5195-5195
- DOI
  10.1126/sciadv.aaz5195
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-20K21663, KAKENHI-PROJECT-20H03593, KAKENHI-PROJECT-18K14840
[Journal Article] Human corneal limbal organoids maintaining limbal stem cell niche function.2020
- Author(s)
  10.Higa K, Higuchi J, Kimoto R, Miyashita H, Shimazaki J, Tsubota K, Shimmura S.
- Journal Title
  
  Stem Cell Res.
  
  Volume: Sep 30;49 Pages: 102012-102012
- DOI
  10.1016/j.scr.2020.102012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09461, KAKENHI-PROJECT-19K09978
[Journal Article] Correlation between tear and aqueous humor cytokine levels in bullous keratopathy.2020
- Author(s)
  3.Tomida D, Yagi-Yaguchi Y, Higa K, Satake Y, Shimazaki J, Yamaguchi T*
- Journal Title
  
  Ocular Surface
  
  Volume: 20 Issue: 4 Pages: 801-807
- DOI
  10.1016/j.jtos.2020.06.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21663
[Journal Article] Aquaporin 1-positive stromal niche-like cells directly interact with N-cadherin-positive clusters in the basal limbal epithelium.2013
- Author(s)
  比嘉一成
- Journal Title
  
  Stem Cell Research
  
  Volume: 10(2) Issue: 2 Pages: 147-155
- DOI
  10.1016/j.scr.2012.11.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591966, KAKENHI-PROJECT-24592646
[Journal Article] N-cadherin in the maintenance of human corneal limbal epithelial progenitor cells in vitro2009
- Author(s)
  Higa K, Shimmura S, Miyashita H, Kato N, Ogawa Y, Kawakita T, Shimazaki J, Tsubota K
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 50(10) Pages: 4640-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791711
[Journal Article] N-cadherin is required to meintain human corneal limbal epithelial progenitor cells in vitro.2009
- Author(s)
  Kazunari Higa
- Journal Title
  
  Invest Ophthalmol Cis Sci. 50巻
  
  Pages: 4640-4645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791711
[Journal Article] Proliferation and differentiation of transplantable epithelial sheets engineered with or without an amniotic membrane carrier2007
- Author(s)
  Higa K, Shimmura S, et al. (corresponding author)
- Journal Title
  
  Invest Ophthalmol Vis Sci 48
  
  Pages: 597-604
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390471
[Journal Article] Hypoxia Enhances the Expansion of Human Limbal Epithelial Progenitor Cells in Vitro.2007
- Author(s)
  Miyashita H, Higa K, Kato N, Shimmura S.
- Journal Title
  
  Invest Ophthalmol Vis Sci (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390471
[Journal Article] Proliferation and Differentiation of Transplantable Rabbit Epithelial Sheets Engineered with or without an Amniotic Membrane Carrier.2007
- Author(s)
  Higa K, Shimmura S, Kato N, et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci (Corresponding author) 48
  
  Pages: 597-604
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390471
[Journal Article] Proteomic analysis of soluble factors secreted by limbal fibroblasts.2006
- Author(s)
  Shimmura S, Miyashita H, Higa K, Yoshida S, Shimazaki J, Tsubota K.
- Journal Title
  
  Mol Vis (Corresponding author) 12
  
  Pages: 478-484
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390471
[Journal Article] Hyaluronic acid-CD 44 interaction mediates the adhesion of lymphocytes by amniotic membrane stroma2005
- Author(s)
  Higa K, Shimmura S, et al.
- Journal Title
  
  Cornea 24・2
  
  Pages: 206-221
- Data Source
  KAKENHI-PROJECT-17390471
[Journal Article] Melanocytes in the corneal limbus interact with K19-positive basal epithelial cells.2005
- Author(s)
  Higa K, Shimmura S, et al.
- Journal Title
  
  Exp Eye Res 81・2
  
  Pages: 218-223
- Data Source
  KAKENHI-PROJECT-17390471
[Presentation] ウサギ角膜輪部機能不全モデルへのヒト角膜中央由来オルガノイドの移植2024
- Author(s)
  比嘉一成、石渡三冬、平山雅敏、山口剛史、榛村重人
- Organizer
  角膜カンファランス2024
- Data Source
  KAKENHI-PROJECT-21K09708
[Presentation] ヒト角膜由来オルガノイドのウサギ角膜輪部機能不全モデルへの移植2024
- Author(s)
  比嘉一成、石渡三冬、平山雅敏、山口剛史、榛村重人
- Organizer
  第23回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-21K09708
[Presentation] Nicotinamide mononucleotide prevents iris atrophy-associated corneal 　endothelial cell loss2023
- Author(s)
  Takefumi Yamaguchi, Rintaro Ogino, Yukari YagiYaguchi, Kazunari Higa, Jun Shimazaki
- Organizer
  ARVO2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21663
[Presentation] Nicotinamide mononucleotide prevents iris atrophy-associated corneal endothelial cell loss2023
- Author(s)
  Takefumi Yamaguchi, Rintaro Ogino, Yukari Yagi-Yaguchi, Hirotsugu Kasamatsu, Reona Kimoto, Kazunari Higa, Jun Shimazaki
- Organizer
  ARVO2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27754
[Presentation] ヒト角膜中央部分から作成した前駆細胞マーカーを発現する由来オルガノイド2022
- Author(s)
  比嘉一成、木本玲緒奈、樋口順子、西迫宗大、平山雅敏、島崎　潤、榛村重人
- Organizer
  第21回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-21K09708
[Presentation] ヒト角膜由来オルガノイド培養における前駆細胞マーカーの発現2022
- Author(s)
  比嘉一成、木本玲緒奈、樋口順子、西迫宗大、平山雅敏、島崎　潤、榛村重人
- Organizer
  角膜カンファランス2022
- Data Source
  KAKENHI-PROJECT-21K09708
[Presentation] メチルセルロースを用いたヒト角膜輪部オルガノイドの培養2021
- Author(s)
  比嘉一成、樋口順子、木本玲緒奈、宮下英之、島崎　潤、坪田一男、榛村重人
- Organizer
  第45回角膜学会総会・第37回日本角膜移植学会
- Data Source
  KAKENHI-PROJECT-18K09461
[Presentation] ヒト角膜輪部オルガノイド培養におけるメチルセルロースの応用2021
- Author(s)
  比嘉一成、樋口順子、木本玲緒奈、宮下英之、島崎　潤、坪田一男、榛村重人
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K09461
[Presentation] 角膜輪部オルガノイドの輪部機能不全モデルへの移植2019
- Author(s)
  比嘉一成、樋口順子、木本玲緒奈、宮下英之、島崎潤、坪田一男、榛村重人
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18K09461
[Presentation] Human limbal organoid transplantation in a rabbit limbal deficiency model.2019
- Author(s)
  Higa, K; Higuchi, J; Kimoto, R; Miyashita, H; Shimazaki, J; Tsubota, K; Shimmura, S
- Organizer
  The Association for Research in Vision and Ophthalmology- Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09461
[Presentation] 輪部機能不全モデルウサギへの角膜輪部オルガノイド移植2019
- Author(s)
  比嘉一成、樋口順子、木本玲緒奈、宮下英之、島崎潤、坪田一男、榛村重人
- Organizer
  角膜間ファランス2019
- Data Source
  KAKENHI-PROJECT-18K09461
[Presentation] 羊膜由来間葉系細胞の角膜輪部上皮シートへの影響2017
- Author(s)
  比嘉一成、樋口順子、鈴木輝政、佐竹良之、山口剛史、島崎潤
- Organizer
  角膜カンファランス2017
- Place of Presentation
  福岡（博多）
- Year and Date
  2017-02-15
- Data Source
  KAKENHI-PROJECT-26462669
[Presentation] 角膜輪部ニッチ培養における低酸素の影響2016
- Author(s)
  比嘉一成、宮下英之、島崎潤、坪田一男、榛村重人
- Organizer
  第３７回　日本炎症・再生学会
- Place of Presentation
  京都
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-15K10907
[Presentation] 少量組織から角膜輪部ニッチ培養法の検討2016
- Author(s)
  比嘉一成、宮下英之、島崎潤、坪田一男、榛村重人
- Organizer
  角膜カンファランス2016
- Place of Presentation
  軽井沢
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-15K10907
[Presentation] Spheroidal cultivation of the human limbal epithelial niche from small limbal tissue.2016
- Author(s)
  Kazunari Higa, Hideyuki Miyashita, Jun Shimazaki, Kazuo Tsubota, Shigeto Shimmura
- Organizer
  2016 ARVO Annual Meeting
- Place of Presentation
  シアトル
- Year and Date
  2016-05-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10907
[Presentation] Spheroidal cultivation of the human limbal epithelial niche from small limbal tissue.2016
- Author(s)
  Kazunari Higa, Hideyuki Miyashita, Jun Shimazaki, Kazuo Tsubota, Shigeto Shimmura
- Organizer
  ARVO2016 Annual meeting
- Place of Presentation
  America (Seattle)
- Year and Date
  2016-04-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10907
[Presentation] 自己少量角膜輪部ニッチ培養法の検討2015
- Author(s)
  比嘉一成、宮下英之、島崎潤、坪田一男、榛村重人
- Organizer
  第３６回　日本炎症・再生学会
- Place of Presentation
  東京
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15K10907
[Presentation] Matrigelで形成した角膜輪部由来spheroidの解析2014
- Author(s)
  比嘉一成、宮下英之、島崎潤、坪田一男、榛村重人
- Organizer
  角膜カンファランス２０１４
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-24592646
[Presentation] N-cadherin陽性の角膜輪部上皮基底細胞直下に存在するニッチ様細胞2011
- Author(s)
  比嘉一成、加藤直子、吉田悟、小川葉子、島崎潤、坪田一男、榛村重人
- Organizer
  角膜カンファランス2011
- Place of Presentation
  品川
- Year and Date
  2011-02-17
- Data Source
  KAKENHI-PROJECT-21791711
[Presentation] Aquaporin 1 positive mesenchymal cell imply existence of cornea limbal niche cells2011
- Author(s)
  Kazunari Higa, Naoko Kato, Satoru Yoshida, Yoko Ogawa, Jun Shimazaki, Kazuo Tsubota, Shigeto Shimmura
- Organizer
  The Association for Research in Vision and Ophthalmology 2011 Annual Meeting
- Place of Presentation
  Fort Lauderdale, Florida, U.S.A.
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-21791711
[Presentation] Aquaporin 1 positive mesenchymal cells imply existence of cornea limbal niche cells2011
- Author(s)
  Higa K, Kato N, Yoshida S, Ogawa Y, Shimazaki J, Tsubota K, Shimmura S
- Organizer
  The Association for Research in Vision and Ophthalmology 2011 Annual Meeting
- Place of Presentation
  Fort Lauderdale, Florida, U. S. A.
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-21791711
[Presentation] 角膜輪部ニッチ様細胞と接する角膜輪部上皮Tiny cellsの解析2011
- Author(s)
  比嘉一成, 加藤直子, 吉田悟, 小川葉子, 島崎潤, 坪田一男, 榛村重人
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-21791711
[Presentation] 角膜輪部ニッチ様細胞と接する角膜輪部上皮Tiny cellsの解析2011
- Author(s)
  比嘉一成, 加藤直子, 吉田悟, 小川葉子, 島崎潤, 坪田一男, 榛村重人
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-21791711
[Presentation] The fate of trans-amplifying cells analyzed by in vivo rabbit model with stainless ring transplantation.2008
- Author(s)
  Kawakita T, Shimmura M, Higa K, Shimazaki J, Tsubota K.
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO)
- Place of Presentation
  Fort Lauderdale, Florida, USA.
- Data Source
  KAKENHI-PROJECT-20791283
[Presentation] N-cadherin expression in hypoxic spheroidal cultivation of human limbal epithelial cells
- Author(s)
  Kazunari Higa, Hideyuki Miyashita, Jun Shimazaki, Kazuo Tsubota, Shigeto Shimmura
- Organizer
  Asia-ARVO
- Place of Presentation
  横浜
- Year and Date
  2015-02-16 – 2015-02-19
- Data Source
  KAKENHI-PROJECT-24592646
[Presentation] 低酸素培養した角膜輪部由来spheroidにおけるN-cadherinの発現
- Author(s)
  比嘉一成、宮下英之、島﨑潤、坪田一男、榛村重人
- Organizer
  角膜カンファランス2015
- Place of Presentation
  高知
- Year and Date
  2015-02-11 – 2015-02-13
- Data Source
  KAKENHI-PROJECT-24592646
[Presentation] 角膜輪部ニッチ培養法の検討
- Author(s)
  比嘉一成、宮下英之、島﨑潤、坪田一男、榛村重人
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24592646

1. Takefumi Yamaguchi (20383771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. SHIMMURA Machiko (80385244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SHIMMURA Shigeto (00235780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. Shimazaki Jun (40170930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 川北哲也 (50408308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 杉本昌弘 (30458963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山本将仁 (90733767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 阿部伸一 (40256300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 長坂新 (40822474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石垣和慶 (00790338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 金蔵孝介 (10508568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 植田幸嗣 (10509110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 野間久史 (70633486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 吉野純 (80383777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KANEKO Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Higa Kazunari 比嘉 一成

HIGA Kazunari 比嘉 一成

Research Projects

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Co-Researchers

角膜オルガノイドにおける角膜輪部幹細胞ーニッチメカニズムの解明Principal Investigator

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咀嚼筋腱・腱膜過形成症の病因解明に向けた基礎研究～“筋内腱”発生機序の探索～

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Establishment of experimental basis to improve the prognosis of corneal transplantation in treating bullous keratoplasty due to pathological aqueous humor.

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Constrction and analysis of limbal niche in the corneal organoidsPrincipal Investigator

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Proposal of a novel therapy for bullous keratopathy based on human-derived multiomics analysis

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Establishment of long-term culture method of limbal organoids using methylcellulose.Principal Investigator

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Spheroidal cultivation of the human limbal epithelial niche from small limbal tissue.Principal Investigator

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The relationship between the amniotic and mesenchymal stem cell, the its effect and preservation

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Analysis of limbal epithelial tiny cells contact with limbal niche like cellsPrincipal Investigator

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Role of N-cadherin in the niche of corneal limbal ephtheliumPrincipal Investigator

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Wound healing model of corneal epithelium using stenless-ring.

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Hypoxic culture in the isolation of corneal stem cells

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[Journal Article] Donor-Related Risk Factors for Graft Decompensation Following Descemet's Stripping Automated Endothelial Keratoplasty2022

Author(s)

Journal Title

Higa Kazunari 比嘉一成

HIGA Kazunari 比嘉一成