Abe Hideharu 安部秀斉

… Alternative Names

Researcher Number	60399342
Affiliation (Current)	2020: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授
Affiliation (based on the past Project Information) *help	2020: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授 2018: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 准教授 2015: 徳島大学, 大学院医歯薬学研究部, 准教授 2011 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 准教授 … More
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Kidney internal medicine / Basic Section 52010:General internal medicine-related / Basic Section 53040:Nephrology-related
Keywords	Principal Investigator Smad1 / 糖尿病性腎症 / BMP4 / コラーゲン / ALK1 / バイオマーカー / 細胞老化 / 加齢 / 糖尿病 / 糸球体硬化 … More Except Principal Investigator バイオマーカー / 老化 / 細胞・組織 / 病理学 / BMP4 / 糖尿病性腎症 / 慢性腎臓病 / ポドサイト / メサンギウム細胞 / 形質変換 / bHLH型転写因子 / Id2 / smooth muscle αactin / 腎臓病理 / 糸球体硬化 / Smad1 / Sox9 / 抗体医療 / BMP / ALK3/6 / 分子標的治療 / エクソゾーム / CKD / エクソソーム / ALK1 / PACE4 / 糖尿病 / ポドサイト障害 / 糖尿病性腎臓病(DKD) / 腎硬化症 / 動脈硬化 / 高血圧 Less

DKDが近年増加している原因の分子メカニズムの解明Ongoing
- Principal Investigator
  
  冨永辰也
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokushima
糖尿病性腎症における特異的ポドサイト障害分子の同定と尿中バイオマーカーの樹立Ongoing
- Principal Investigator
  
  櫻井明子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokushima
糖尿病における進行性腎障害の病態特異的バイオマーカー樹立と修復機構解明Principal InvestigatorOngoing
- Principal Investigator
  
  安部秀斉
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokushima
サイトカインプロセシング酵素を標的にした新規CKD治療薬の開発Ongoing
- Principal Investigator
  
  冨永辰也
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Elucidation of molecular mechanisms and development of vascular complications in diabetic nephropathy and renal arteriosclerosisPrincipal Investigator
- Principal Investigator
  
  ABE Hideharu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Molecular mechanism underlying aging-related nephron lossPrincipal Investigator
- Principal Investigator
  
  ABE Hideharu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Establishment of non-invasive diagnostic method for CKD by using urinary exosomes.
- Principal Investigator
  
  DOI Toshio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Development of Specific Biomarker and Molecular Targeting Therapy for Diabetic Nephropathy by RAS-independent Pathway
- Principal Investigator
  
  DOI Toshio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Molecular mechanisms for irreversible phenotypic changes leading to renal failure in chronic kidney diseases.Principal Investigator
- Principal Investigator
  
  ABE Hideharu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
MOLECULAR MECHANISM OF GLOMERULOSCLEROSIS IN AGING
- Principal Investigator
  
  MATSUBARA Takeshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyoto University
BMP/ALK/Smad1 signaling pathway and analysis of specifiobiomarkers in the progression of glomerulosclerosisPrincipal Investigator
- Principal Investigator
  
  ABE Hideharu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
  Research Institute for Production Development
MOLECULAR MECHANISMS OF GLOMERULOSCLEROSIS IN AGING
- Principal Investigator
  
  MATSUBARA Takeshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyoto University
腎特異的な形質変換規定因子のクローニングと機能解析
- Principal Investigator
  
  DOI Toshio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Fundamental Analysis of Regulation of Smadl-related Genes in Diabetic NephropathyPrincipal Investigator
- Principal Investigator
  
  ABE Hideharu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Research Institute for Production Development

[Book] 腎疾患の病態形成におけるBMP4・Smad1の役割2011
- Author(s)
  安部秀斉
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591033
[Book] 糖尿病カレントライブラリー(5)2006
- Author(s)
  安部秀斉
- Total Pages
  240
- Publisher
  文光堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590853
[Book] 腎と透析2005
- Author(s)
  安部秀斉
- Total Pages
  122
- Publisher
  東京医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590853
[Journal Article] Induction of steady-state glomeruloid sphere by self-assembly from human embryonic kidney cells2019
- Author(s)
  Abe Hideharu、Sakurai Akiko、Ochi Arisa
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 508 Pages: 654-659
- DOI
  10.1016/j.bbrc.2018.11.160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415, KAKENHI-PROJECT-18K08245
[Journal Article] An adjustment in BMP4 function represents a treatment for diabetic nephropathy and podocyte injury2018
- Author(s)
  Fujita Yui、Tominaga Tatsuya、Abe Hideharu、Kangawa Yumi、Fukushima Naoshi、Ueda Otoya、Jishage Kou-ichi、Kishi Seiji、Murakami Taichi、Saga Yumiko、Kanwar Yashpal S.、Nagai Kojiro、Doi Toshio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 13011-13011
- DOI
  10.1038/s41598-018-31464-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08245, KAKENHI-PROJECT-16K09619
[Journal Article] Urinary Exosomal mRNA of WT1 as Diagnostic and Prognostic Biomarker for Diabetic Nephropathy2018
- Author(s)
  Abe Hideharu、Sakurai Akiko、Ono Hiroyuki、Hayashi Sanae、Yoshimoto Sakiya、Ochi Arisa、Ueda Sayo、Nishimura Kenji、Shibata Eriko、Tamaki Masanori、Kishi Fumi、Kishi Seiji、Murakami Taichi、Nagai Kojiro、Doi Toshio
- Journal Title
  
  The Journal of Medical Investigation
  
  Volume: 65 Issue: 3.4 Pages: 208-215
- DOI
  10.2152/jmi.65.208
- NAID
  130007495809
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415, KAKENHI-PROJECT-16K09619
[Journal Article] Urinary IgG4 and Smad1 Are Specific Biomarkers for Renal Structural and Functional Changes in Early Stages of Diabetic Nephropathy2018
- Author(s)
  Doi T, Moriya T, Fujita Y, Minagawa N, Usami M, Sasaki T, Abe H, Kishi S, Murakami T, Ouchi M, Ichien G, Yamamoto K, Ikeda H, Koezuka Y, Takamatsu N, Shima K, Mauer M, Nagai K, Tominaga T.
- Journal Title
  
  Diabetes
  
  Volume: 67 Pages: 986-993
- DOI
  10.2337/db17-1043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09265, KAKENHI-PROJECT-16K09619
[Journal Article] Novel Interplay Between Smad1 and Smad3 Phosphorylation via AGE Regulates the Progression of Diabetic Nephropathy2018
- Author(s)
  Ono Hiroyuki、Abe Hideharu、Sakurai Akiko、Ochi Arisa、Tominaga Tatsuya、Tamaki Masanori、Kishi Seiji、Murakami Taichi、Nagai Kojiro、Kohashi Masayuki、Doi Toshio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 10548-10548
- DOI
  10.1038/s41598-018-28439-1
- NAID
  120006535060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415, KAKENHI-PROJECT-18K08245, KAKENHI-PROJECT-16K09619
[Journal Article] Probucol modulates Nrf2 function and ameliorates diabetic nephropathy in db/db mice.2017
- Author(s)
  Arai H, Abe H, Sakurai A, Yamashita K, Murayama T, Minami M, Yoshikawa T, Kohashi M, Nozako M, Yokode M, Doi T.
- Journal Title
  
  Medical Research Archives.
  
  Volume: ４ Pages: 1-16
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09265
[Journal Article] Conditional Deletion of Smad1 Ameliorates Glomerular Injury in Progressive Glomerulonephritis.2016
- Author(s)
  Araki M, Matsubara T, Abe H, Torikoshi K, Mima A, Iehara N, Fukatsu A, Kita T, Arai H, Doi T
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Pages: 31216-31216
- DOI
  10.1038/srep31216
- NAID
  120006345067
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461230, KAKENHI-PROJECT-15K09265, KAKENHI-PROJECT-16K09613
[Journal Article] Bone morphogenetic protein 4 and　Smad1 mediate extracellular matrix production in the development of　diabetic nephropathy.2015
- Author(s)
  Matsubara, Takeshi; Araki, Makoto; Abe, Hideharu et al.
- Journal Title
  
  Diabetes
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591201
[Journal Article] Bone Morphogenetic Protein 4 and Smad1 Mediate Extracellular Matrix Production in the Development of Diabetic Nephropathy2015
- Author(s)
  Matsubara T, Araki M, Abe H, Ueda O, Jishage K, Mima A, Goto C, Tominaga T, Kinosaki M, Kishi S, Nagai K, Iehara N, Fukushima N, Kita T, Arai H, Doi T.
- Journal Title
  
  Diabetes
  
  Volume: ６４ Pages: 2978-2990
- DOI
  10.2337/db14-0893
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09265, KAKENHI-PROJECT-26461230, KAKENHI-PROJECT-25461221
[Journal Article] Polymorphism in the human matrix Gla protein gene is associated with the progression of vascular calcification in maintenance hemodialysis patients2013
- Author(s)
  Yoshikawa K, Abe H, Tominaga T, Nakamura M, Kishi S, Matsuura M, Nagai K, Tsuchida K, Minakuchi J, Doi T
- Journal Title
  
  Clin Exp Nephrol.
- DOI
  10.1007/s10157-013-0785-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] Distribution of and factors contributing to chronic kidney disease in a middle-aged working population.2013
- Author(s)
  Furuichi K1, Shimizu M, Toyama T, Koya D, Koshino Y, Abe H, Mori K, Satoh H, Imanishi M, Iwano M, Yamauchi H, Kusano E, Fujimoto S, Suzuki Y, Okuda S, Kitagawa K, Iwata Y, Kaneko S, Nishi S, Yokoyama H, Ueda Y, Haneda M, Makino H, Wada T
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 17 Pages: 466-476
- DOI
  10.1007/s10157-013-0778-8
- NAID
  50009002851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390225, KAKENHI-PROJECT-24406028, KAKENHI-PROJECT-24591201, KAKENHI-PROJECT-24659570, KAKENHI-PROJECT-25461237, KAKENHI-PROJECT-25670269
[Journal Article] Acute Glomerulonephritis in an Immunocompetent Elderly Woman after Contact with a Child who Had Been Diagnosed as Erythema Infectiosum2012
- Author(s)
  Kishi S, Yamada S, Kishi F, Shibata E, Matsuura M, Nagai K, Mima A, Abe H, Doi T.
- Journal Title
  
  Internal Medicine
  
  Volume: 51 Issue: 16 Pages: 2197-2201
- DOI
  10.2169/internalmedicine.51.7919
- NAID
  130002062315
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] Scleraxis modulates bone morphogenetic protein 4 (BMP4)-Smad1-smooth muscle α actin (SMA) signal transduction in diabetic nephropathy.2012
- Author(s)
  Abe H, Tominaga T, Matsubara T, Abe N, Kishi S, Nagai K, Murakami T, Araoka T, Doi T.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Pages: 20430-20442
- DOI
  10.1074/jbc.m111.275610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-22390169, KAKENHI-PROJECT-23659445, KAKENHI-PROJECT-24591201, KAKENHI-PROJECT-24659279
[Journal Article] SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy.2011
- Author(s)
  Kishi S, Abe H, Akiyama H, Tominaga T, Murakami T, Mima A, Nagai K, Kishi F, Matsuura M, Matsubara T, Iehara N, Ueda O, Fukushima N, Jishage KI, Doi T.
- Journal Title
  
  Jbiol Chem
  
  Volume: 286(37) Pages: 32162-32169
- DOI
  10.1074/jbc.m111.244541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591032, KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
[Journal Article] 心腎貧血連関における心血管イベント予測新規バイオマーカー血中Smad1の解析2011
- Author(s)
  安部秀斉
- Journal Title
  
  腎臓
  
  Volume: 34(2) Pages: 112-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659445
[Journal Article] Role of Smad1 in diabetic nephropathy : Molecular mechanisms and implications as a diagnostic marker.2011
- Author(s)
  Abe H., et al.
- Journal Title
  
  Histol Histopathol.
  
  Volume: 26 Pages: 531-541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] Role of Smad1 in diabetic nephropathy : Molecular mechanisms and implications as a diagnostic marker2011
- Author(s)
  Abe H, Matsubara T, Arai H, Doi T
- Journal Title
  
  Histol Histopathol
  
  Volume: 26(4) Pages: 531-541
- URL
  http://www.hh.um.es/Abstracts/Vol_26/26_4/26_4_531.htm
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591033
[Journal Article] Activation of Src Mediates PDGF-Induced Smad1 Phosphorylation and Contributes to the Progression of Glomerulosclerosis in Glomerulonephritis2011
- Author(s)
  Mima A, Abe H, Nagai K, Arai H, Matsubara T, Araki M, Torikoshi K, Tominaga T, Iehara N, Fukatsu A, Kita T, Doi T
- Journal Title
  
  PLoS One
  
  Volume: 6(3)
- URL
  http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0017929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591033
[Journal Article] Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy.2011
- Author(s)
  Tominaga T, Abe H, Ueda O, Goto C, Nakahara K, Murakami T, Mima A, Nagai K, Araoka T, Kishi S, Fukushima N, Jishage KI, Doi T
- Journal Title
  
  J Biol Chem.
  
  Volume: 286(22) Pages: 20109-16
- DOI
  10.1074/jbc.m110.179382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590628, KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
[Journal Article] BMP4・Smad1シグナルと糖尿病性腎症2011
- Author(s)
  安部秀斉、冨永辰也, 松原雄, 土井俊夫
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 53(7) Pages: 1000-1005
- NAID
  10030343457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659445
[Journal Article] Role of Smad1 in diabetic nephropathy: Molecular mechanisms and implications as a diagnostic marker2011
- Author(s)
  Abe H, Matsubara T, Arai H, Doi T
- Journal Title
  
  Histol Histopathol.
  
  Volume: 26(4) Pages: 531-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790808
[Journal Article] BMP4・Smad1シグナルと糖尿病性腎症2011
- Author(s)
  安部秀斉, ら
- Journal Title
  
  本腎臓学会誌
  
  Volume: 53 Pages: 1000-1005
- NAID
  10030343457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591033
[Journal Article] BMP4・Smad1シグナルと糖尿病性腎症2011
- Author(s)
  安部秀斉, ら
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 53 Pages: 1000-1005
- NAID
  10030343457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] BMP4・Smad1シグナルと糖尿病性腎症2011
- Author(s)
  安部秀斉ら
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 53 Pages: 1000-1005
- NAID
  10030343457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659445
[Journal Article] Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis.2011
- Author(s)
  Mima A, Abe H, Nagai K, Arai H, Matsubara T, Araki M, Torikoshi K, Tominaga T, Iehara N, Fukatsu A, Kita T, Doi T
- Journal Title
  
  PLoS One.
  
  Volume: 6(3)
- DOI
  10.1371/journal.pone.0017929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
[Journal Article] Recent progress in understanding the molecular pathogenesis of diabetic nephropathy2011
- Author(s)
  Abe H
- Journal Title
  
  Rinsho Byori
  
  Volume: 59(2) Pages: 179-86
- NAID
  10029427023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591033
[Journal Article] 糖尿病性腎症の病因解析の進歩2011
- Author(s)
  安部秀斉
- Journal Title
  
  臨床病理
  
  Volume: 59(2) Pages: 179-186
- NAID
  10029427023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659445
[Journal Article] An autopsy case of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with intestinal bleeding in chronic renal failure2011
- Author(s)
  Mima A, Shiota F, Matsubara T, Iehara N, Akagi T, Abe H, Nagai K, Matsuura M, Murakami T, Kishi S, Araoka T, Kishi F, Kondo N, Shigeta R, Yoshikawa K, Kita T, Doi T, Fukatsu A
- Journal Title
  
  Ren Fail.
  
  Volume: 33 Pages: 622-625
- DOI
  10.3109/0886022x.2011.585730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] MPO-ANCA-positive anti-glomerular basement membrane antibody disease successfully treated byplasma exchange and immunosuppressive therapy.2011
- Author(s)
  Murakami T, Nagai K, Matsuura M, Kondo N, Kishi S, Araoka T, Kishi F, Sakiyama T, Mima A, Bando Y, Abe H, Doi T.
- Journal Title
  
  Ren Fail
  
  Volume: 33 Pages: 626-631
- DOI
  10.3109/0886022x.2011.581401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] Role of Smad1 in diabetic nephropathy: Molecular mechanisms and implications as a diagnostic marker2011
- Author(s)
  Abe H, Matsubara T, Arai H, Doi T
- Journal Title
  
  Histol Histopathol.
  
  Volume: 26 Pages: 531-541
- URL
  http://www.hh.um.es/Abstracts/Vol_26/26_4/26_4_531.htm
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] Transcription factor 7-like 2 (TCF7L2) regulates activin receptor-like kinase 1 (ALK1)/Smad1 pathway for development of diabetic nephropathy.2010
- Author(s)
  Araoka T, Abe H, Tominaga T, Mima A, Matsubara T, Murakami T, Kishi S, Nagai K, Doi T
- Journal Title
  
  Mol Cells.
  
  Volume: 30(3) Pages: 209-18
- DOI
  10.1007/s10059-010-0109-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
[Journal Article] rophoblast glycoprotein: possible candidate mediating podocyte injuries in glomerulonephritis2010
- Author(s)
  Murakami T, Abe H, Nagai K, Tominaga T, Takamatsu N, Matsubara T, Araoka T, Kishi S, Takahashi T, Mima A, Takai Y, Kopp JB, Doi T.
- Journal Title
  
  Am J Nephrol.
  
  Volume: 32(6) Pages: 505-521
- DOI
  10.1159/000321366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591032, KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-22390169
[Journal Article] 糖尿病性腎症の発症前診断による抗血管老化治療への試み2009
- Author(s)
  安部秀斉
- Journal Title
  
  未病と抗老化 vol.18(1)
  
  Pages: 42-46
- NAID
  40016672488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590973
[Journal Article] 糖尿病とネフローゼ症候群2009
- Author(s)
  安部秀斉
- Journal Title
  
  日本内科学会雑誌 vol.98(5)
  
  Pages: 1048-1054
- NAID
  10024934704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590973
[Journal Article] CKDにおける糖尿病性腎症の位置づけ-診療の課題と今後の展望[総説]2008
- Author(s)
  美馬晶、安部秀斉、土井俊夫
- Journal Title
  
  Diabetes Frontie vol.19(5)
  
  Pages: 583-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590973
[Journal Article] 糖尿病性腎症の発症・進展の分子病態2008
- Author(s)
  安部秀斉、土井俊夫
- Journal Title
  
  日本内科学会雑誌医学と医療の最前線 vol.97(4)
  
  Pages: 820-826
- NAID
  10021253977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590973
[Journal Article] The current clinical problems for early phase of diabetic nephropathy and approach for pathogenesis of diabetic nephropathy2008
- Author(s)
  Doi T, Mima A, Matsubara T, Tominaga T, Arai H, Abe H
- Journal Title
  
  Diabetes Res Clin Pract Nov13(82)Suppl 1
  
  Pages: 21-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590973
[Journal Article] Urinary Smadl is a novel marker to predict later onset of mesangial matrix expansion in diabetic nephropathy2008
- Author(s)
  Mima A, Arai H, Matsubara T, Abe H, Nagai K, Tamura Y, Torikoshi K, Araki M, Kanamori H, Takahashi T, Tominaga T, Matsuura M, Iehara N, Fukatsu A, Kita T, Doi T
- Journal Title
  
  Diabetes 57(6)
  
  Pages: 1712-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590973
[Journal Article] Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephrapathy2007
- Author(s)
  Kanamori H, hiatsubara T, Mima A, Sumi E, Nagai K, Takahashi T, Abe H, Iehara N, Fukatsu A, Okamoto H, Kita T, Doi T, Arai H
- Journal Title
  
  Biochem Biaphys Res Commun 360
  
  Pages: 772-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590973
[Patent] 腎臓様組織の製造方法2017
- Inventor(s)
  安部秀斉
- Industrial Property Rights Holder
  国立大学法人徳島大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-15K09265
[Presentation] iPS/ES細胞を用いない、糸球体スフェロイド作成2019
- Author(s)
  越智ありさ、櫻井明子、安部秀斉
- Organizer
  徳島医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07415
[Presentation] 糖尿病性腎症の糸球体硬化抑制過程におけるSmad1の新規リン酸化部位の同定と解析2017
- Author(s)
  小野広幸、安部秀斉, 上田紗代、西村賢二、田蒔昌憲、村上太一, 岸誠司, 長井幸二郎, 土井俊夫
- Organizer
  第255回徳島医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09265
[Presentation] The Role of BMP4 Signal Pathway on the Podocyte Injury in Diabetic Early Stage.2016
- Author(s)
  Fujita Y, Tominaga T, Murakami T, Kishi S, Nagai K, Abe H, Doi T
- Organizer
  49th American Society of Nephrology (ASN) Annual Meeting
- Place of Presentation
  Chicago, IL, U.S.A
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09265
[Presentation] 糖尿病患者の血管合併症を判定する尿中バイオマーカー樹立2014
- Author(s)
  安部秀斉
- Organizer
  2014年度Diabetes Masters Conference
- Place of Presentation
  東京プリンスホテル（東京都・港区）
- Year and Date
  2014-12-13
- Invited
- Data Source
  KAKENHI-PROJECT-24591201
[Presentation] Multiple regulatory pathways of BMP-Smad axis through a sclerosis-specific basic HLH transcription factor in diabetic nephropathy2013
- Author(s)
  Yui Fujita, Akiko Sakurai, Tatsuya Tominaga, Sanae Hayashi, Naoko Abe, Toshio Doi, Hideharu Abe
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-24591201
[Presentation] Predictive biomarkers for kidney function declines: podocyte-derived exosomal transcriptional factors2012
- Author(s)
  安部尚子、林早苗、土井俊夫、安部秀斉
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-23659445
[Presentation] Predictive biomarkers for kidney function declines: podocyte-derived exosomal transcriptional factors2012
- Author(s)
  安部尚子他
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23659445
[Presentation] 糸球体腎炎におけるCD44作用機序の解析2012
- Author(s)
  金井麻衣、冨永辰也、安部秀斉、美馬晶、林早苗、長井幸二郎、土井俊夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-23659445
[Presentation] BMP4/Smad1 Signaling: A Novel Therapeutic Target for the Progression of Diabetic Nephropathy, (Oral presentation)2011
- Author(s)
  Takeshi Matsubara, Hideharu Abe, et. Al
- Organizer
  the American Diabetes Association's 71st Scientific Sessions
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2011-06-26
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] 尿中エクソゾームを用いた慢性腎臓病の非侵襲的診断法と予後予測2011
- Author(s)
  林早苗、安部秀斉、冨永辰也、安部尚子、近藤直樹、土井俊夫
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23659445
[Presentation] 新規バイオマーカーとしての尿中エクソゾームによる慢性腎臓病患者の病態解析2011
- Author(s)
  安部尚子ら
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Data Source
  KAKENHI-PROJECT-23659445
[Presentation] 糖尿病性腎症の分子病態-BMP4-Smad1シグナル2011
- Author(s)
  安部秀斉
- Organizer
  第41回日本腎臓学会西部学術総会シンポジウム
- Place of Presentation
  徳島市あわぎんホール(徳島県郷土文化会館)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-22390169
[Presentation] 糖尿病性腎症の分子病態-BMP4-Smad1シグナル2011
- Author(s)
  安部秀斉
- Organizer
  第41回日本腎臓学会西部学術総会
- Place of Presentation
  あわぎんホール(徳島県郷土文化会館)(徳島市)(招待講演)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] Trophoblast glycoprotein regulates the podocyte injuries in experimental glomerulonephritis.2011
- Author(s)
  Murakami T, Abe H, Nagai K, Tominaga T, Matsuura M, Kishi S, Kishi F, Yoshikawa K, Kondo N, Jeffrey Kopp, Doi T
- Organizer
  World Congress of Nephrology 2011
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] OVEREXPRESSION OF Smad1 EXACERBATES GLOMERULAR LESIONS IN DIABETIC NEPHROPATHY THROUGH BMP-42011
- Author(s)
  Takeshi Matsubara, Hideharu Abe, et. al
- Organizer
  The World Congress of Nephrology 2011
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2011-08-04
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] Overexpression of Smad1 Causes Remarkable Glomerulosclerosis in Diabetic Mice2011
- Author(s)
  Matsubara T, Abe H, Ueda O, Jishage K, Mima A, Goto C, Tominaga T, Nagai K, Iehara N, Fukushima N, Fukatsu A, Arai H, Doi T
- Organizer
  American Diabetes Association 71th Scientific Session, San Diego Convention Center-San
- Place of Presentation
  Diego U.S.A.
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] PIASyはメサンギウム細胞においてE12と共役し<SMAの発現を制御する2011
- Author(s)
  鳥越和雄, 大島隆幸, 平野隆弘, 安部秀斉, 松雄, 荒木真, 家原典之, 深津敦司, 荒井秀典, 土井俊夫
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] 糖尿病性腎症における糸球体硬化とアルブミン尿には異なる病態形成機構が存在する2011
- Author(s)
  松原雄, 安部秀斉, 他
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] 新規バイオマーカーとしての尿中エクソゾームによる慢性腎臓病患者の病態解析2011
- Author(s)
  安部尚子、安部秀斉、土井俊夫
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  岡山コンベンションセンター(岡山県)
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-23659445
[Presentation] Conditional Knockout of Smad1 Ameliorates Glomerulosclerosis in Progressive Glomerulonephritis2010
- Author(s)
  Araki M, Abe H, Torikoshi K, Mima A, Matsubara T, Iehara N, Fukatsu A, Salant DJ, Arai H, Doi T
- Organizer
  43^<rd> American Society of Nephrology(ASN) Annual Meeting
- Place of Presentation
  Denver, CO, U.S.A.
- Year and Date
  2010-11-21
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] Smad1は糖尿病性糸球体硬化症の進展に重要な役割を果たす2010
- Author(s)
  松原雄, 安部秀斉, 他
- Organizer
  日本臨床分子医学会学術総会
- Place of Presentation
  東京
- Year and Date
  2010-04-10
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] PIASy Regulates SMα-Actin Expression by Interacting with E12 in Mesangial Proliferative Glomerulonephritis2010
- Author(s)
  Torikoshi K, Araki M, Matsubara T, Mima A, Hirano T, Abe H, Fukatsu A, Arai H, Doi T
- Organizer
  43^<rd> American Society of Nephrology(ASN) Annual Meeting
- Place of Presentation
  Denver, CO, U.S.A.
- Year and Date
  2010-11-21
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] BMP4/ Smad1 Signaling Is a Critical Therapeutic Target for Diabetic Nephropathy2010
- Author(s)
  Matsubara T, Abe H, Ueda O, Tominaga T, Mima A, Nagai K, Torikoshi K, Araki M, Goto C, Kinosaki M, Jishage K, Fukushima N, Iehara N, Fukatsu A, Arai H, Doi T
- Organizer
  43^<rd> American Society of Nephrology(ASN) Annual Meeting
- Place of Presentation
  Denver, CO, U.S.A.
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] BMP4/Smad1 Signaling Is a Critical Therapeutic Target for Diabetic Nephropathy2010
- Author(s)
  Takeshi Matsubara, Hideharu Abe, et. al
- Organizer
  Renal Week 2010 American Society of Nephrology Annual Meeting
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] 糖尿病性腎症に関わる新たな治療標的分子の検討2010
- Author(s)
  松原雄, 安部秀斉, 他
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] Chondrogenic phenotypic change contributes to the irreversible progression of the diabetic nephropathy2010
- Author(s)
  Kishi S, Abe H, Murakami T, Tominaga T, Nagai K, Mima A, Doi T
- Organizer
  50th The American Society for Cell Biology Annual Meeting,
- Place of Presentation
  Philadelphia, U.S.A.
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] IV型コラーゲンの転写制御因子Smad1は骨形成因子BMP4を介して糖尿病性腎症進展に中心的役割を果たす2010
- Author(s)
  松原雄, 安部秀斉, 他
- Organizer
  糖尿病合併症学会
- Place of Presentation
  大津
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] Overexpression of Smad1 Causes Remarkable Glomerulosclerosis in Diabetic Mice2010
- Author(s)
  Takeshi Matsubara, Hideharu Abe, Otoya Ueda, Kou-ichi Jishage, Akira Mima, Chisato Goto, Tatsuya Tominaga, Makoto Araki, Kazuo Torikoshi, Kojiro Nagai, Noriyuki Iehara, Atsushi Fukatsu, Naoshi Fukushima, Hidenori Arai, Toshio Doi
- Organizer
  the American Diabetes Association's 70th Scientific Sessions
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21790808
[Presentation] Chondrogenic Potential of Mesangial Cells in Diabetic Nephropathy2009
- Author(s)
  Kishi S, Abe H, Akiyama H, Doi T
- Organizer
  49th The American Society for Cell Biology Annual Meeting
- Place of Presentation
  San Diego, U.S.A.
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] The Novel Function of Trophoblast Glycoprotein(Tpbg) on Actin Remodeling in Podocyte Injured in Experimental Glomerulonephritis2009
- Author(s)
  Murakami T, Abe H, Matsuura M, Araoka T, Kishi S, Tominaga T, Shigeta R, Yoshikawa K, Kishi F, Takamatsu N, Takahashi T, Mima A, Nagai K, Takai Y, Doi T
- Organizer
  American Society of Nephrology(ASN) Annual Meeting
- Place of Presentation
  Pennsylvania, U.S.A.
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] 慢性腎臓病(CKD)から不可逆的糸球体硬化症に至る分子病態2009
- Author(s)
  岸誠司、安部秀斉、秋山治彦、土井俊夫
- Organizer
  第106回日本内科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] TCF7L2(Transcription factor 7-like 2) Regulates Activin Receptor-Like Kinase1(ALK1)/ Smad1 Pathway for Development of Diabetic Nephropathy.(Araoka T : Young Investigator Travel Grant Award)2009
- Author(s)
  Araoka T, Abe H, Matsuura M, Murakami T, Kishi S, Tominaga T, Shigeta R, Yoshikawa K, Kishi F, Mima A, Takahashi T, Hirano T, Doi T
- Organizer
  American Diabetes Association 69th Scientific Session
- Place of Presentation
  New Orleans., U.S.A.
- Data Source
  KAKENHI-PROJECT-21591033
[Presentation] Molecular Mechanisms of Diabetic Nephropathy2009
- Author(s)
  Araoka T, Tominaga T, Abe H, Doi T
- Organizer
  International symposium of Diabetes
- Place of Presentation
  Tokushima, Japan
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎症発症・進展におけるBMP4の中心的役割2008
- Author(s)
  冨永辰也、安部秀斉、村上太一、荒岡利和、立部貴典、寺社下浩一、土井俊夫
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] BMP4/Smadl signaling is a key pathtvay in diabetic nephropathy2008
- Author(s)
  ominaga T, Abe H, Murakami T, Ar-aoka T, Shigeta R, Kishi S, Yoshikawa K, Matsuura M, Mima A, Doi T
- Organizer
  48th The American Society for Cell Biology Annual Meeting
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎症におけるBMP4の硬化進展機構2008
- Author(s)
  安部秀斉
- Organizer
  第12回シンポジウム糖尿病
- Place of Presentation
  東京
- Year and Date
  2008-04-19
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎症の進行決定因子ALK1の発現調節機構の解析2008
- Author(s)
  荒岡利和、安部秀斉、冨永辰也、村上太一、土井俊夫
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎症の発症・進展におけるBMP4の作用機構2008
- Author(s)
  冨永辰也、安部秀斉、美馬晶、村上太一、荒岡利和、繁田令子、岸誠司、吉川和寛、岸史、松浦元一、高橋利和、土井俊夫
- Organizer
  第14回分子腎臓研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎症の発症・進展におけるBMP4の作用機構2008
- Author(s)
  冨永辰也、安部秀斉、美馬晶、村上太一、荒岡利和、繁田令子、岸誠司、吉川和寛、岸史、松浦元一、高橋利和、土井俊夫
- Organizer
  第20回日本糖尿病性腎症研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] Src/Smad1経路は糸球体腎炎発症進展において中心的な役割を演じる2008
- Author(s)
  美馬晶、荒井秀典、松原雄、安部秀斉、高橋利和、荒木真、鳥越和雄、家原典之、深津敦司、北徹、土井俊夫
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] BMP4/Smadl signaling is a key pathway in diabetic nephropathy2008
- Author(s)
  Tominaga T, Abe H, Murakami T, Araoka T, Mima T, Doi T
- Organizer
  第16回日本血管生物医学会学術集会(The 6th Korea-Japan Joint Symposium on Vascular Biology)
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 腎硬化関連bHLH型転写因子Scleraxisのクローニングと機能解析2007
- Author(s)
  安部秀斉、冨永辰也、村上太一、荒岡利和、片上幹子、中村玲、高松典通、松浦元一、高橋利和、土井俊夫
- Organizer
  第14回分子腎臓研究会
- Place of Presentation
  東京
- Year and Date
  2007-09-01
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 腎硬化関連bHLH型転写因子Scleraxisのクローニング2007
- Author(s)
  安部秀斉、冨永辰也、土井俊夫
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] Mima A, Arai H, Matsubara T, Abe H, Kanamori H, Iehara N, Fukatsu A, Kita T, Doi T2007
- Author(s)
  Urinary Smadl Is a Novel diagnostic Marker To Predict Mesangial Matrix Expansion in Rat Diabetic Nephropathy
- Organizer
  American Society of Nephrology(ASN)Annual Meeting
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 尿中Smad1は糖尿病性腎症の治療効果を反映する新規マーカーになりうる2007
- Author(s)
  美馬晶、荒井秀典、松原雄、安部秀斉、金森弘志、角栄里子、冨永辰也、高橋利和、松浦元一、家原典之、深津敦司、北徹、土井俊夫
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] Role of Nitric Oxide Synthase(NOS)in the Progression of Diabetic Nephropathy2007
- Author(s)
  Kanamori H, Matsubara T, Mima A, Sumi E, Nagai K, Takahashi T, Abe H, Iehara N, Fukatsu A, Okamoto H, Kita T, Doi T, Arai H
- Organizer
  merican Society of Nephrology(ASN)Annual Meeting
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎硬化症関連bHLH型転写因子Scleraxisのクローニングと機能解析2007
- Author(s)
  安部秀斉、冨永辰也、村上太一、荒岡利和、片上幹子、松浦元一、高橋利和、土井俊夫
- Organizer
  第15回血管生物医学会
- Place of Presentation
  福岡
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 硬化・線維化関連bHLH型転写因子Scleraxisのクローニングと機能解析2007
- Author(s)
  安部秀斉、冨永辰也、村上太一、荒岡利和、片上幹子、中村玲、高松典通、松浦元一、高橋利和、土井俊夫
- Organizer
  第30回目本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病における新規腎硬化関連因子ALK1の転写調節機構の解析2007
- Author(s)
  荒岡利和、安部秀斉、冨永辰也、平野隆弘、村上太一、土井俊夫
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] Urinary Smadl Is a Novel Diagnostic Marker To Predict Mesangial Matrix Expansion in Rat Diabetic Nephropathy2007
- Author(s)
  Mima A, Arai H, Matsubara T, Abe H, Kanamori H, Iehara N, Fukatsu A, Kita T, Doi T.
- Organizer
  American Society of Nephrology(ASN)Annual Meeting
- Place of Presentation
  San Francisco,U.S.A.
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎症の進展における一酸化窒素の意義2007
- Author(s)
  金森弘志、松原雄、美馬晶、角栄里子、高橋利和、安部秀斉、家原典之、深津敦司、北徹、土井俊夫、荒井秀典
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎症におけるMCP-1/CCR2の役割2007
- Author(s)
  金森弘志、松原雄、美馬晶、高橋利和、安部秀斉、家原典之、深津敦司、北徹、土井俊夫、荒井秀典
- Organizer
  第19回日本糖尿病性腎症研究会
- Place of Presentation
  東京
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] Scleraxis Critically Regulates Diabetic Glomerulosclerosis-Related Genes under the Control of BMP2/42007
- Author(s)
  Abe H, Tominaga T, Takahashi T, Nakamura A, Araoka T, Murakami T, Doi T
- Organizer
  American Society of Nephrology (ASN) Annual Meeting
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] Cloning and characterization of Scleraxis : fibrosis-and sclerosis-specific basic HLH transcription factor2007
- Author(s)
  Abe H, Tominaga T, Araoka T, Murakami T, Takahashi T, Doi T
- Organizer
  47th The American Society for Cell Biology Annual Meeting
- Place of Presentation
  Washington D.C., U.S.A.
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] 糖尿病性腎症の糸球体硬化におけるMCP-1/CCR2の役割2007
- Author(s)
  金森弘志、松原雄、美馬晶、角栄里子、長井幸二郎、高橋利和、安部秀斉、家原典之、深津敦司、北徹、土井俊夫、荒井秀典
- Organizer
  第11回シンポジウム糖尿病
- Place of Presentation
  東京
- Year and Date
  2007-04-14
- Data Source
  KAKENHI-PROJECT-19590973
[Presentation] FlashとE2Aの新規相互作用はTNF-α-p21によって細胞増殖と細胞老化を制御する
- Author(s)
  小野広幸、平野隆弘、櫻井明子、土井俊夫、安部秀斉
- Organizer
  第37回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-24 – 2014-11-26
- Data Source
  KAKENHI-PROJECT-24591201
[Presentation] 糖尿病のポドサイトにおけるBMP-CXCR7シグナル異常の検出法
- Author(s)
  櫻井明子、安部秀斉、長井幸一郎、村上太一、安部尚子、土井俊夫
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-24591201
[Presentation] 腎機能低下予測バイオマーカーとしてのポドサイト由来エクソゾーム内転写因子
- Author(s)
  安部尚子他
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-22390169

1. TOMINAGA Tatsuya (80425446)

# of Collaborated Projects: 6 results

# of Collaborated Products: 13 results
2. DOI Toshio (60183498)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
3. NAGAI Kojiro (40542048)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
4. ARAI Hidenori (60232021)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
5. KISHI Seiji (10519507)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
6. MIMA Akira (00432401)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
7. MATSUBARA Takeshi (90422964)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
8. IEHARA Noriyuki (20281727)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. 櫻井明子 (70707900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. YANAGITA Motoko (70378769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FUKATSU Atsushi (90247685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. AKIYAMA Haruhiko (60402830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. ABE Naoko (70623271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
14. MIZUNO Akira (80219641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TSUKAGUCHI Hiroyasu (60335792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 村上太一 (30403736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
17. MATSUURA Motokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. WADA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. SATOH Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 森潔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 今井圓裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 横山仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Abe Hideharu 安部 秀斉

安部 秀斉 アベ ヒデハル

ABE Hideharu 安部 秀斉

Research Projects

Research Products

Co-Researchers

DKDが近年増加している原因の分子メカニズムの解明Ongoing

Principal Investigator

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糖尿病性腎症における特異的ポドサイト障害分子の同定と尿中バイオマーカーの樹立Ongoing

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糖尿病における進行性腎障害の病態特異的バイオマーカー樹立と修復機構解明Principal InvestigatorOngoing

Principal Investigator

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サイトカインプロセシング酵素を標的にした新規CKD治療薬の開発Ongoing

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Elucidation of molecular mechanisms and development of vascular complications in diabetic nephropathy and renal arteriosclerosisPrincipal Investigator

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Molecular mechanism underlying aging-related nephron lossPrincipal Investigator

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Establishment of non-invasive diagnostic method for CKD by using urinary exosomes.

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Development of Specific Biomarker and Molecular Targeting Therapy for Diabetic Nephropathy by RAS-independent Pathway

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Molecular mechanisms for irreversible phenotypic changes leading to renal failure in chronic kidney diseases.Principal Investigator

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MOLECULAR MECHANISM OF GLOMERULOSCLEROSIS IN AGING

Principal Investigator

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BMP/ALK/Smad1 signaling pathway and analysis of specifiobiomarkers in the progression of glomerulosclerosisPrincipal Investigator

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MOLECULAR MECHANISMS OF GLOMERULOSCLEROSIS IN AGING

Principal Investigator

Project Period (FY)

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腎特異的な形質変換規定因子のクローニングと機能解析

Principal Investigator

Abe Hideharu 安部秀斉

安部秀斉アベヒデハル

ABE Hideharu 安部秀斉

[Journal Article] Bone morphogenetic protein 4 and　Smad1 mediate extracellular matrix production in the development of　diabetic nephropathy.2015