Arai Satoko 新井郷子

… Alternative Names

ARAI Satoko 新井郷子

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Researcher Number	60422276
Other IDs	https://orcid.org/0000-0002-6145-8686
Affiliation (Current)	2025: 一般社団法人AIM医学研究所, 分子病態医科学研究部門, 研究部門長
Affiliation (based on the past Project Information) *help	2023 – 2024: 一般社団法人AIM医学研究所, 研究部門, 副所長 2020 – 2022: 東京大学, 大学院医学系研究科(医学部), 准教授 2016 – 2018: 東京大学, 大学院医学系研究科(医学部), 准教授 2015: 東京大学, 大学院医学系研究科, 准教授 2014: 東京大学, 医学(系)研究科(研究院), 准教授 … More 2014: 東京大学, 医学(系)研究科(研究院), 特任准教授 2013: 東京大学, 医学(系)研究科(研究院), 講師 2010 – 2012: 東京大学, 大学院・医学系研究科, 講師 2007 – 2008: The University of Tokyo, 大学院・医学系研究科, 講師 2006: 東京大学, 大学院医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Hematology / Pathological medical chemistry / Transformative Research Areas, Section (III) / Kidney internal medicine / Circulatory organs internal medicine Except Principal Investigator Transformative Research Areas, Section (III) / Gastroenterology / Human genetics
Keywords	Principal Investigator AIM / 食細胞機構 / 宿主防御機構 / 感染防御機構 / 重症肺感染症 / 炎症性組織レジリエンス / 修復的マクロファージ / アイフレイル / 線維化 / 急性腎臓病 … More / 慢性腎臓病 / 慢性炎症 / メタボリックシンドローム / HCC / 生活習慣病 / 血液疾患 / クロマチン制御 / 造血 / ポリコームグループタンパク質 / 白血病 / エピジェネティクス / 血球分化 / ポリコーム … More Except Principal Investigator 炎症性組織レンジエンス / 組織障害エントロピー / 炎症性組織レジリエンス / 炎症記憶 / 炎症収束 / 生活習慣病 / AIM / 肝癌 / 脂肪肝 / NASH / アポトーシス / マクロファージ / 動脈硬化 Less

Elucidation of mechanisms for enhancement of host defense response in severe pulmonary infectionPrincipal Investigator
- Principal Investigator
  
  新井郷子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  The Institute for AIM Medicine
Elucidation of the roles of restorative macrophages in inflammatory tissue resiliencePrincipal Investigator
- Principal Investigator
  
  Arai Satoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The Institute for AIM Medicine
  The University of Tokyo
Integrated elucidation of inflammatory tissue-resilience and tissue damage-entropy;Creation of innovative science for resolution of inflammation
- Principal Investigator
  
  Hirahara Kiyoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Chiba University
Regulation of visual deterioration and ocular diseases using phagocytic mechanismsPrincipal Investigator
- Principal Investigator
  
  Arai Satoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  The University of Tokyo
脂肪肝肝癌の発症機序におけるＡＩＭの関連に関する研究Principal Investigator
- Principal Investigator
  
  新井郷子, 宮崎徹
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Investigation of roles of circulating protein AIM in chronic kidney disease and its therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  Arai Satoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Obesity and liver diseases: towards clarification of mechanisms for NASH
- Principal Investigator
  
  Miyazaki Toru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Development of prophylaxis and therapy system for metabolic stmdorome by regulation of AIM functionPrincipal Investigator
- Principal Investigator
  
  ARAI Satoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Analysis for hematopoiesis and hematologic diseases by L3MBTL1 conditional knockout mice.Principal Investigator
- Principal Investigator
  
  ARAI Satoko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Analysis of entire roles for AIM in atherosclerogenesis
- Principal Investigator
  
  MIYAZAKI Toru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  The University of Tokyo
新しいポリコーム分子MBT-1による白血病制御を目指してPrincipal Investigator
- Principal Investigator
  
  新井郷子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

[Book] AIM: 炎症と生活習慣病を繋ぐ分子2013
- Author(s)
  新井郷子, 宮崎徹
- Total Pages
  7
- Publisher
  中外医学社　Annual Review 糖尿病・代謝・内分泌2013
- Data Source
  KAKENHI-PROJECT-24390196
[Book] 日本臨床2013
- Author(s)
  新井郷子, 宮崎徹
- Total Pages
  9
- Publisher
  マクロファージ由来タンパク質AIMの最新知見―その多様な機能と生活習慣病との関連性―
- Data Source
  KAKENHI-PROJECT-25253056
[Book] マクロファージ由来タンパク質AIMの最新知見―その多様な機能と生活習慣病との関連性―2013
- Author(s)
  新井郷子, 宮崎徹
- Total Pages
  9
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-24390196
[Book] 実験医学12月号 vol.26 No,192008
- Author(s)
  新井郷子、宮崎徹
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19390094
[Journal Article] 腎疾患におけるAIMの関与2024
- Author(s)
  新井響子,宮崎徹
- Journal Title
  
  アニムス
  
  Volume: 118 Pages: 34-38
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Journal Article] Apoptosis inhibitor of macrophages/CD5L enhances phagocytosis in the trabecular meshwork cells and regulates ocular hypertension2023
- Author(s)
  Nemoto Hotaka、Honjo Megumi、Arai Satoko、Miyazaki Toru、Aihara Makoto
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 238 Issue: 10 Pages: 2451-2467
- DOI
  10.1002/jcp.31097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09807, KAKENHI-ORGANIZER-21H05120, KAKENHI-PROJECT-23K27749
[Journal Article] Differences in the expression of multidrug resistance proteins in chronic rhinosinusitis according to endotype2023
- Author(s)
  Iinuma Tomohisa、Yonekura Syuji、Hirahara Kiyoshi、Kurita Junya、Yoneda Riyo、Arai Tomoyuki、Sonobe Yuri、Shinmi Rie、Okamoto Yoshitaka、Hanazawa Toyoyuki
- Journal Title
  
  Allergol. Int.
  
  Volume: 72 Issue: 4 Pages: 564-572
- DOI
  10.1016/j.alit.2023.03.008
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09739, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-23K27607
[Journal Article] AIM/CD5L ameliorates autoimmune arthritis by promoting removal of inflammatory DAMPs at the lesions2023
- Author(s)
  Yasuda Keisuke、Shimodan Shieri、Maehara Natsumi、Hirota Aika、Iijima Ruka、Nishijima Akemi、Mori Haruka、Toyama Ran、Ito Atsumi、Yoshikawa Yuri、Arai Satoko、Miyazaki Toru
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 142 Pages: 103149-103149
- DOI
  10.1016/j.jaut.2023.103149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Journal Article] Single-cell immunoprofiling after immunotherapy for allergic rhinitis reveals functional suppression of pathogenic TH2 cells and clonal conversion2022
- Author(s)
  Iinuma Tomohisa、Kiuchi Masahiro、Hirahara Kiyoshi、Kurita Junya、Kokubo Kota、Yagyu Hiroyuki、Yoneda Riyo、Arai Tomoyuki、Sonobe Yuri、Fukuyo Masaki、Kaneda Atsushi、Yonekura Syuji、Nakayama Toshinori、Okamoto Yoshitaka、Hanazawa Toyoyuki
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 150 Issue: 4 Pages: 850-860.e5
- DOI
  10.1016/j.jaci.2022.06.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07164, KAKENHI-PROJECT-22K09739, KAKENHI-PROJECT-22K15484, KAKENHI-PROJECT-22K15485, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05121, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-21K20754
[Journal Article] Two independent modes of kidney stone suppression achieved by AIM/CD5L and KIM-12022
- Author(s)
  Matsuura Kyohei、Maehara Natsumi、Hirota Aika、Eguchi Ayaka、Yasuda Keisuke、Taniguchi Kaori、Nishijima Akemi、Matsuhashi Nobuyuki、Shiga Yoshiyuki、Ishii Rumi、Iguchi Yasuhiro、Tanabe Kazunari、Arai Satoko、Miyazaki Toru
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 783-783
- DOI
  10.1038/s42003-022-03750-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Journal Article] High salt exacerbates acute kidney injury by disturbing the activation of CD5L/apoptosis inhibitor of macrophage (AIM) protein2021
- Author(s)
  Wang Ching-Ting、Tezuka Tetsushi、Takeda Naoki、Araki Kimi、Arai Satoko、Miyazaki Toru
- Journal Title
  
  PLOS ONE
  
  Volume: 16(11) Issue: 11 Pages: e0260449-e0260449
- DOI
  10.1371/journal.pone.0260449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05120, KAKENHI-PROJECT-23K21285
[Journal Article] AIM associated with the IgM pentamer: attackers on stand-by at aircraft carrier2018
- Author(s)
  Miyazaki Toru、Yamazaki Tomoko、Sugisawa Ryoichi、Gershwin M Eric、Arai Satoko
- Journal Title
  
  Cellular and Molecular Immunology
  
  Volume: - Issue: 6 Pages: 563-574
- DOI
  10.1038/cmi.2017.141
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05313, KAKENHI-PROJECT-16H06389
[Journal Article] Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice2017
- Author(s)
  Tomita T, Arai S, Kitada K, Mizuno M, Suzuki Y, Sakata F, Nakano D, Hiramoto E, Takei Y, Maruyama S, Nishiyama A, Matsuo S, Miyazaki T, Ito Y.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 6450-6450
- DOI
  10.1038/s41598-017-06824-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04697, KAKENHI-PROJECT-16H05313, KAKENHI-PROJECT-15K09288, KAKENHI-PROJECT-15K15063, KAKENHI-PROJECT-16H06389
[Journal Article] A proteolytic modification of AIM promotes its renal excretion.2016
- Author(s)
  Yamazaki T, Sugisawa R, Hiramoto E, Takai R, Matsumoto A, Senda Y, Nakashima K, Nelson PS, Lucas JM, Morgan A, Li Z, Yamamura KI, Arai S, Miyazaki T
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 38762-38762
- DOI
  10.1038/srep38762
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05313, KAKENHI-PROJECT-16H06389
[Journal Article] Impact of feline AIM on the susceptibility of cats to renal disease.2016
- Author(s)
  Sugisawa R, Hiramoto E, Matsuoka S, Iwai S, Takai R, Yamazaki T, Mori N, Okada Y, Takeda N, Yamamura KI, Arai T, Arai S, Miyazaki T.
- Journal Title
  
  Scientific Report
  
  Volume: 6 Issue: 1 Pages: 35251-35251
- DOI
  10.1038/srep35251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450435, KAKENHI-PROJECT-16H05313, KAKENHI-PROJECT-16H06389
[Journal Article] 1.Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice.2016
- Author(s)
  Arai S, Kitada K, Yamazaki T, Takai R, Zhang X, Tsugawa Y, Sugisawa R, Matsumoto A, Mori M, Yoshihara Y, Doi K, Maehara N, Kusunoki S, Takahata A, Noiri E, Suzuki Y, Yahagi N, Nishiyama A, Gunaratnam L, Takano T, Miyazaki T.
- Journal Title
  
  Nature Medicine
  
  Volume: 22 Issue: 2 Pages: 183-193
- DOI
  10.1038/nm.4012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253056
[Journal Article] A defense system against multiple diseases via biological garbage clearance mediated by soluble scavenger proteins.2015
- Author(s)
  Miyazaki T, Arai S.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 35 Issue: 4 Pages: 203-209
- DOI
  10.2492/inflammregen.35.203
- NAID
  130005103501
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25253056
[Journal Article] Tricking an ancient immune function to eradicate hepatocellular carcinoma2015
- Author(s)
  Miyazaki T, Arai S
- Journal Title
  
  Molecular & Cellular Oncology
  
  Volume: 2 Issue: 3 Pages: e985915-e985915
- DOI
  10.4161/23723556.2014.985915
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-25253056
[Journal Article] Stabilization and augmentation of circulating AIM in mice by synthesized IgM-Fc.2014
- Author(s)
  Kai T, Yamazaki T, Arai S, Miyazaki T
- Journal Title
  
  PLOS ONE
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390196
[Journal Article] MafB promotes atherosclerosis by inhibiting foam-cell apoptosis2014
- Author(s)
  Hamada M, Nakamura M, Tran MT, Moriguchi T, Hong C, Ohsumi T, Dinh TT, Kusakabe M, Hattori M, Katsumata T, Arai S, Nakashima K, Kudo T, Kuroda E, Wu CH, Kao PH, Sakai M, Shimano H, Miyazaki T, Tontonz P, Takahashi S
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 3147-3147
- DOI
  10.1038/ncomms4147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21220009, KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591145, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25253056, KAKENHI-PROJECT-25461494, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26670448
[Journal Article] Stabilization and Augmentation of Circulating AIM in Mice by Synthesized IgM-Fc2014
- Author(s)
  Kai T, Yamazaki T, Arai S, Miyazaki T
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 5 Pages: e97037-e97037
- DOI
  10.1371/journal.pone.0097037
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-25253056
[Journal Article] Impacts of the apoptosis inhibitor of macrophage (AIM) on obesity-associated inflammatory diseases.2014
- Author(s)
  Arai S, Miyazaki T
- Journal Title
  
  Semin Immunopathol
  
  Volume: 36 Issue: 1 Pages: 3-12
- DOI
  10.1007/s00281-013-0405-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-25253056
[Journal Article] The macrophage soluble receptor AIM/Api6/CD5L displays a broad pathogen recognition spectrum and is involved in early response to microbial aggression.2014
- Author(s)
  Martinez VG, Escoda-Ferran C, Tadeu Simoes I, Arai S, Orta Mascaro M, Carreras E, Martinez-Florensa M, Yelamos J, Miyazaki T, Lozano F
- Journal Title
  
  Cell Mol Immunol
  
  Volume: Epub ahead of print Issue: 4 Pages: 343-354
- DOI
  10.1038/cmi.2014.12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-25253056
[Journal Article] Stabilization and augmentation of circulating AIM in mice by synthesized IgM-Fc.2014
- Author(s)
  Kai T, Arai S, Yamazaki T, Miyazaki T
- Journal Title
  
  PLOS ONE
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253056
[Journal Article] Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation2014
- Author(s)
  Maehara N, Arai S, Mori M, Iwamura Y, Kurokawa J, Kai T, Kusunoki S, Taniguchi K, Ikeda K, Ohara O, Yamamura K, Miyazaki T
- Journal Title
  
  Cell Reports
  
  Volume: 9 Issue: 1 Pages: 61-74
- DOI
  10.1016/j.celrep.2014.08.058
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-25253056, KAKENHI-PROJECT-26861314, KAKENHI-PROJECT-221S0001
[Journal Article] Circulating AIM as an Indicator of Liver Damage and Hepatocellular Carcinoma in Humans2014
- Author(s)
  Yamazaki T, Mori M, Arai S, Tateishi R, Abe M, Ban M, Nishijima A, Maeda M, Asano T, Kai T, Izumino K, Takahashi J, Aoyama K, Harada S, Takebayashi T, Gunji T, Ohnishi S, Seto S, Yoshida Y, Hiasa Y, Koike K, Yamamura K, Inoue K, Miyazaki T
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 10 Pages: e109123-e109123
- DOI
  10.1371/journal.pone.0109123
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-25253056, KAKENHI-PROJECT-26861314, KAKENHI-PROJECT-221S0001
[Journal Article] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells2013
- Author(s)
  Arai, S., et al.
- Journal Title
  
  Cell Rep.
  
  Volume: 3 Issue: 4 Pages: 1-12
- DOI
  10.1016/j.celrep.2013.03.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05522, KAKENHI-PROJECT-23390091, KAKENHI-PROJECT-23791107, KAKENHI-PROJECT-24249021, KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-24659175, KAKENHI-PROJECT-25461494, KAKENHI-PROJECT-221S0001
[Journal Article] AIM : 炎症と生活習慣病を繋ぐ分子2013
- Author(s)
  新井郷子
- Journal Title
  
  Annual Review糖尿病・代謝・内分泌
  
  Pages: 99-105
- Data Source
  KAKENHI-PROJECT-24390196
[Journal Article] マクロファージ由来因子AIMによる生活習慣病の病態制御2012
- Author(s)
  新井郷子
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 1231-1236
- Data Source
  KAKENHI-PROJECT-24390196
[Journal Article] 肥満から慢性炎症、そして疾患へ-AIMによる慢性炎症誘発のメカニズム-2012
- Author(s)
  新井郷子
- Journal Title
  
  血管医学
  
  Volume: 13 Pages: 213-219
- Data Source
  KAKENHI-PROJECT-24390196
[Journal Article] アポトーシスと動脈硬化2012
- Author(s)
  新井郷子
- Journal Title
  
  動脈硬化予防
  
  Volume: 11 Pages: 36-41
- Data Source
  KAKENHI-PROJECT-24390196
[Journal Article] DEDD による細胞周期と細胞サイズの調節2009
- Author(s)
  倉部誠也, 新井郷子, 宮崎徹
- Journal Title
  
  生化学 81
  
  Pages: 24-26
- Data Source
  KAKENHI-PROJECT-19390094
[Journal Article] The death effector domain-containing DEDD supports S6K1 activity via preventing Cdk1-dependent inhibitory phosphorylation2009
- Author(s)
  Kurabe, N., Arai, S., Nishijima, A., Kubota, N., Suizu, F., Mori, M., Kurokawa, J., Kondo-Miyazaki, M., Ide, T., Murakami, K., Miyake, K., Ueki, K., Koga, K., Yatomi, Y., Tashiro, F., Noguchi, M., Kadowaki, T., Miyazaki, T.
- Journal Title
  
  J.Biol.Chem 284
  
  Pages: 5050-5055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390094
[Journal Article] マクロファージのアポトーシス制御による新しい動脈硬化治療の可能性2008
- Author(s)
  新井郷子, 宮崎徹
- Journal Title
  
  実験医学 26
  
  Pages: 3030-3036
- Data Source
  KAKENHI-PROJECT-19390094
[Journal Article] Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1.2007
- Author(s)
  新井郷子
- Journal Title
  
  Proceedings of National Academy of Sciences of the United States of America 104巻7号
  
  Pages: 2289-2294
- Data Source
  KAKENHI-PROJECT-18790647
[Journal Article] Two distinct controls of mitotic Cdk1/cyclin B1 activity requisite for cell growth prior to cell division2007
- Author(s)
  Miyazaki, T. & Arai, S.
- Journal Title
  
  Cell Cycle 6
  
  Pages: 1419-1425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390094
[Journal Article] アポトーシス関連分子DEDDの新たな機能-細胞周期および細胞のサイズの制御2006
- Author(s)
  新井郷子
- Journal Title
  
  実験医学 24巻11号
  
  Pages: 1599-1603
- Data Source
  KAKENHI-PROJECT-18790647
[Presentation] IgM-mediated modulation of AIM: Enhancing clearance of biological waste2024
- Author(s)
  Satoko Arai
- Organizer
  The International Symposium on Resolution of Inflammation
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] 研究者の夢と目覚め～血中タンパク質AIMの臨床応用をめざして～2023
- Author(s)
  新井郷子
- Organizer
  ダイバーシティ研究環境実現イニシアティブ（先端型）第3回オープンイノベーション講演会
- Invited
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] Facilitation of disease repair through phagocytic removal of different inflammatory organic wastes by AIM/CD5L2023
- Author(s)
  Toru Miyazaki, Satoko Arai
- Organizer
  Poster Presentation IUIS 2023, 18th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] Facilitation of disease repair through phagocytic removal of different inflammatory elements by AIM/CD5L2023
- Author(s)
  Toru Miyazaki, Satoko Arai
- Organizer
  3rd RESOLUTION DAYS
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] 腎結石症改善に向けた最新知見－血中タンパク質AIMの結石抑制における新たな役割の発見－2023
- Author(s)
  新井郷子
- Organizer
  第14回日本臨床一般検査学会、第20回スキルアップ講習会
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] 血中タンパク質AIMの炎症性疾患における役割とその治療・診断応用2023
- Author(s)
  新井郷子
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] 血中タンパク質AIMを用いた難治性慢性疾患に対する治療的・診断的応用2023
- Author(s)
  新井郷子
- Organizer
  日本生理学会　第100回記念大会
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] AIM/CD5L分子表面ネガティブ・チャージ・クラスターの機能解析2023
- Author(s)
  石井和浩, 新井郷子, 宮崎徹
- Organizer
  ポスターセッション第46回日本分子生物学会年会
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] A role of the phagocytic removal system in resolution of inflammation and its therapeutic implication2022
- Author(s)
  Satoko Arai
- Organizer
  第51回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] Phagocytic removal of body-derived inflammatory elements and disease repair promoted by AIM2022
- Author(s)
  Toru Miyazaki, Arai Satoko
- Organizer
  EMBO Workshop; Phagocytosis of dying cells: Molecules, mechanisms, and therapeutic implications
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] Impact of circulating AIM on self-pathogen removal and its potential clinical applications2022
- Author(s)
  Satoko Arai
- Organizer
  2022 Japanese-French Frontiers of Science Symposium (JFFoS)
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] マクロファージ由来タンパク質AIMのセルフ・パソジェン除去機能を介した炎症収束～急性腎障害から脳梗塞まで～2022
- Author(s)
  新井郷子
- Organizer
  千葉大学リーディング研究育成プログラム「希少・難治性疾患に対する革新的治療創生研究シンポジウム」
- Invited
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] 偽性アルドステロン症自然発症マウスの確立と腎臓におけるMac-2BPの機能解明の試み2022
- Author(s)
  江口彩花, 新井郷子, 宮崎徹
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] 高塩負荷は血中タンパク質AIM/CD5Lの活性化を妨げることにより急性腎障害を悪化させる2021
- Author(s)
  Wang CT, 手塚哲史, 竹田直樹, 荒木喜美, 新井郷子, 宮崎徹
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] AIM/CD5LによるDAMPsの除去を介した脳梗塞の病態改善2021
- Author(s)
  前原奈都美, 谷口香織, 新井郷子, 宮崎徹
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-ORGANIZER-21H05120
[Presentation] Expression of AIM by large peritoneal macrophages (LPMs) and its role in phagocytic activity2017
- Author(s)
  Satoko Arai, Toru Miyazaki
- Organizer
  Keystone Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 血中タンパク質による急性腎障害の治癒メカニズムとその臨床応用の可能性2017
- Author(s)
  新井　郷子
- Organizer
  第43回関東腎研究会
- Place of Presentation
  経団連会館（東京都千代田区）
- Year and Date
  2017-01-21
- Invited
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 血中タンパク質AIMによる異物除去機構を介した疾患の制御2017
- Author(s)
  新井郷子
- Organizer
  第35回内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] ネコAIM独自のIgM高親和性が肥満病態に及ぼす影響の検討2017
- Author(s)
  杉澤良一，新井郷子，宮崎徹
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] Study on activation of circulating AIM in multiple diseases-from NASH-HCC to acute lindly injury-2017
- Author(s)
  Arai Satoko
- Organizer
  MPUTC2017 Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 血中タンパク質AIMによる異物除去機構を介した新しい疾患制御パラダイム2016
- Author(s)
  新井郷子、宮崎徹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 尿中排泄に伴うAIMの修飾とその機能的変化2016
- Author(s)
  山崎　智子、新井　郷子、宮崎　徹
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] AIMネコ化マウスを用いたネコ腎不全の検討2016
- Author(s)
  杉澤　良一、平本　絵美莉、新井　郷子、宮崎　徹
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 腎線維化におけるAIMの役割の解析と治療応用へ向けた検討2016
- Author(s)
  髙井　亮輔、新井　郷子、宮崎　徹
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] Dedefferentiation of renal tubular epithelial cells to phagocytes to ameliorate acute kidney injury through scavenging necrotic cell debris deposited with apoptosis inhibitor of macrophage (AIM) protein2016
- Author(s)
  新井　郷子、山崎　智子、宮崎　徹
- Organizer
  Cell Symposia -100 Years of Phagocytes-
- Place of Presentation
  Giardini Naxos, Italy
- Year and Date
  2016-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] ネコ特異的な腎疾患自己治療機構の欠損2016
- Author(s)
  杉澤　良一、松岡　茂、平本　絵美莉、新井　郷子、宮崎　徹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 血中におけるAIMの切断とその機能的変化2016
- Author(s)
  山崎　智子、新井　郷子、宮崎　徹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 血中AIM活性化ファクターの開発とその疾患治療応用2016
- Author(s)
  平本絵美莉、松岡茂、山崎智子、新井郷子、宮崎徹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] ヒトAIMの疾患治療応用に向けた最適化2016
- Author(s)
  中村　恵子、新井　郷子、宮崎　徹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] ネコAIM独自の特性に起因したネコ腎不全好発機序の解明と治療応用への検討2016
- Author(s)
  杉澤　良一、松岡　茂、平本　絵美莉、新井　郷子、宮崎　徹
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 腎障害における初期線維化の重要性とAIMの役割2016
- Author(s)
  髙井　亮輔、新井　郷子、宮崎　徹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 大型ネコ科動物におけるイエネコ特有のAIM（Apoptosis Inhibitor of Macrophage）特性の解析2016
- Author(s)
  髙井　亮輔、森伸子、新井　郷子、新井　敏郎、宮崎　徹
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16H05313
[Presentation] 肝臓におけるAIMの補体活性化によるがん除去機構2014
- Author(s)
  前原奈都美, 新井郷子, 森真弓, 宮崎徹
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] ヒトにおける肝障害及び肝がんの指標としての血中AIM濃度2014
- Author(s)
  山崎智子, 新井郷子, 宮崎　徹
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25253056
[Presentation] マクロファージ由来タンパク質AIMによる生体の新規恒常性維持機構2014
- Author(s)
  新井郷子
- Organizer
  第7回食品免疫学会次世代シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-06-30
- Invited
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Circulating AIM prevents hepatocellular carcinoma through complement activation2014
- Author(s)
  新井郷子, 宮崎　徹
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-25253056
[Presentation] ヒトにおける肝障害及び肝がんの指標としての血中AIM濃度2014
- Author(s)
  山崎智子, 新井郷子, 宮崎徹
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Prevention of hepatocellular carcinoma by circulating AIM through complement activation2014
- Author(s)
  Toru Miyazaki, Natsumi Maehara, Mayumi Mori, Satoko Arai
- Organizer
  Cell Symposium: Hallmark of Cancer
- Place of Presentation
  Beijing, China
- Year and Date
  2014-11-10
- Data Source
  KAKENHI-PROJECT-25253056
[Presentation] Prevention of hepatocellular carcinoma by circulating AIM through complement activation2014
- Author(s)
  Miyazaki T, Maehara N, Mori M, Arai S
- Organizer
  Cell Symposium: Hallmark of Cancer
- Place of Presentation
  Beijing, China
- Year and Date
  2014-11-10
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Circulating AIM prevents hepatocellular carcinoma through complement activation2014
- Author(s)
  新井郷子, 宮崎徹
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] マクロファージ由来タンパク質AIMによる生体の新規恒常性維持機構2014
- Author(s)
  新井郷子
- Organizer
  第7回食品免疫学会次世代シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-06-30
- Invited
- Data Source
  KAKENHI-PROJECT-25253056
[Presentation] 肝臓におけるAIMの補体活性化によるがん除去機構2014
- Author(s)
  前原奈都美, 新井郷子, 森　真弓, 宮崎　徹
- Organizer
  第37回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25253056
[Presentation] A role for macrophage-derived AIM in humoral immune response and obesity-associated autoimmunity2012
- Author(s)
  新井郷子
- Organizer
  The 99th America Association of Immunology Annual Meeteing
- Place of Presentation
  米国, ボストン
- Year and Date
  2012-05-08
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Obesity-associated autoantibody production requires AIM for retaining the immunecomplex on follicular dendritic cells2012
- Author(s)
  新井郷子
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Obesity-associated autoantibody production reauires AIM for retaining the immunecomplex on follicular dendritic cells2012
- Author(s)
  新井郷子
- Organizer
  EUROPEAN CONGRESS OF IMMUNOLOGY
- Place of Presentation
  英国, グラスゴー
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] MBTドメインを持つポリコームグループタンパク質の血球分化および初期発生における役割2007
- Author(s)
  新井郷子
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18790647
[Presentation] Roles for the mbt-containing Polycomb group proteins in hematopoiesis and early embryogenesis2007
- Author(s)
  新井郷子
- Organizer
  International Symposium on Advanced Functional Genomics
- Place of Presentation
  かずさアカデミアセンター
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18790647
[Presentation] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells
- Author(s)
  Arai S, Honda S., Shibuya A., Li Q, Miyazaki T
- Organizer
  2. 15th International Congress of Immunology
- Place of Presentation
  Milan, Itay
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells.
- Author(s)
  Arai S
- Organizer
  Cell Symposia, Immunometabolism: from Mechanism to Therapy
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells
- Author(s)
  Arai S, Honda S., Shibuya A., Li Q, Miyazaki T
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells.
- Author(s)
  Arai S
- Organizer
  The 3rd CSI/JSI/KAI Joint Symposium 2013
- Place of Presentation
  Pohang, Korea
- Data Source
  KAKENHI-PROJECT-25253056
[Presentation] besity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells.
- Author(s)
  Arai S, Honda S., Shibuya A., Li Q, Miyazaki T
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-25253056
[Presentation] besity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells.
- Author(s)
  Arai S, Honda S., Shibuya A., Li Q, Miyazaki T
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  MiIlan, Italy
- Data Source
  KAKENHI-PROJECT-25253056
[Presentation] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells.
- Author(s)
  Arai S
- Organizer
  The 3rd CSI/JSI/KAI Joint Symposium 2013
- Place of Presentation
  Pohang, Korea
- Data Source
  KAKENHI-PROJECT-24390196
[Presentation] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells.
- Author(s)
  Arai S
- Organizer
  Cell Symposia, Immunometabolism: from Mechanism to Therapy
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-25253056

1. MIYAZAKI Toru (30396270)

# of Collaborated Projects: 4 results

# of Collaborated Products: 30 results
2. Hirahara Kiyoshi (00707193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 相原一 (80222462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 三上洋平 (80528662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ITO yasuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HACZEYNI FAHRETTIN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. FUKUYO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. ARAI Toshiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 本庄恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 森伸子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 武井佳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Arai Satoko 新井 郷子

ARAI Satoko 新井 郷子

Research Projects

Research Products

Co-Researchers

Elucidation of mechanisms for enhancement of host defense response in severe pulmonary infectionPrincipal Investigator

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Elucidation of the roles of restorative macrophages in inflammatory tissue resiliencePrincipal Investigator

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Integrated elucidation of inflammatory tissue-resilience and tissue damage-entropy;Creation of innovative science for resolution of inflammation

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Regulation of visual deterioration and ocular diseases using phagocytic mechanismsPrincipal Investigator

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脂肪肝肝癌の発症機序におけるＡＩＭの関連に関する研究Principal Investigator

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Investigation of roles of circulating protein AIM in chronic kidney disease and its therapeutic applicationPrincipal Investigator

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Obesity and liver diseases: towards clarification of mechanisms for NASH

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Development of prophylaxis and therapy system for metabolic stmdorome by regulation of AIM functionPrincipal Investigator

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Analysis for hematopoiesis and hematologic diseases by L3MBTL1 conditional knockout mice.Principal Investigator

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Analysis of entire roles for AIM in atherosclerogenesis

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新しいポリコーム分子MBT-1による白血病制御を目指してPrincipal Investigator

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Research Field

Research Institution

[Book] AIM: 炎症と生活習慣病を繋ぐ分子2013

Author(s)

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Data Source

[Book] 日本臨床2013

Author(s)

Total Pages

Publisher

Arai Satoko 新井郷子

ARAI Satoko 新井郷子