Morishita Asahiro 森下朝洋

… Alternative Names

森下朝洋モリシタアサヒロ

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Researcher Number	60423430
Affiliation (Current)	2025: 香川大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 香川大学, 医学部附属病院, 講師 2018: 香川大学, 医学部附属病院, 助教 2017: 香川大学, 医学部附属病院, その他 2015 – 2016: 香川大学, 医学部, 助教 2007: 香川大, 医学部附属病院 2006: 香川大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 52010:General internal medicine-related / Laboratory medicine / Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 52010:General internal medicine-related / Gastroenterology / General internal medicine(including psychosomatic medicine) / Tumor diagnostics
Keywords	Principal Investigator マイクロRNA / 免疫化学療法の治療抵抗性 / マイクロＲＮＡ / マクロファージ / 細胞治療 / NASH / MYD88 / トランスレーショナルリサーチ / 分子生物学 / ガレクチン9 … More / ガレクチン９ / 非アルコール性脂肪性肝炎 / 肝癌 / 大腸癌 … More Except Principal Investigator microRNA / 肝細胞癌 / ガレクチン-9 / micro RNA / 耐性株 / 分子標的治療薬 / 抗がん作用 / 耐性癌細胞 / エピガロカテキンガレート / Galectin-9 / Galectin-9 microRNA / 胆管細胞癌 / エクソソーム / 転移性肝癌 / 自己免疫性肝疾患 / 原発性胆汁性胆管炎 / Ｇａｌ-9 / Ｇａｌ－９ / Gal-9 / 遺伝子 / 老化 / メタボリック症候群 / 癌 / 加齢 / トランスジェニックマウス / miRNA / Transgenic mouse / バイオマーカー / exosome / 消化管間葉系腫瘍 / 消化管粘膜下腫瘍 Less

非アルコール性脂肪性肝炎由来肝細胞癌に対する免疫化学療法の治療抵抗性の解明Principal Investigator
- Principal Investigator
  
  森下朝洋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagawa University
Examination of the effect of combination therapy of galectin-9 and epigallocatechin gallate on hepatocellular carcinoma
- Principal Investigator
  
  正木勉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagawa University
非アルコール性脂肪性肝炎進展を抑制するマクロファージを用いた新しい細胞治療Principal Investigator
- Principal Investigator
  
  森下朝洋
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagawa University
Anti-tumor effect of Galectin-9 on metastatic hepatocellular carcinoma and its microRNA basis
- Principal Investigator
  
  Masaki Tsutomu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagawa University
Prediction of prognosis targeting microRNAs in exosomes in primary biliary cholangitis
- Principal Investigator
  
  Nomura Takako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagawa University
Identification of microRNAs that regulate Galectin 9 to suppress nonalcoholic steatohepatitis progressionPrincipal Investigator
- Principal Investigator
  
  Morishita Asahiro
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagawa University
Functional analysis of miR-301a in aging, metabolic syndrome and carcinogenesis
- Principal Investigator
  
  Fujita Koji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Kagawa University
Basic study on treatment of hepatocellular carcinoma targetted of Gal-9 exosomes
- Principal Investigator
  
  Masaki Tsutomu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University
Elucidation of pathway and prognostic factor prediction derived from microRNA analysis in gastrointestinal submucosal tumor
- Principal Investigator
  
  Kobara Hideki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kagawa University
正常大腸粘膜および大腸癌におけるプロテオーム解析と癌特異的タンパク質の機能解析Principal Investigator
- Principal Investigator
  
  森下朝洋
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University

All 2023 2022 2021 2018 2017 2016

All Journal Article Presentation

[Journal Article] Can microRNA-96-5p serve as a therapeutic molecule in the near future?2022
- Author(s)
  Masaki T, Tani J, Morishita A.
- Journal Title
  
  Hepatol Res
  
  Volume: 52巻1項
- Data Source
  KAKENHI-PROJECT-19K08370
[Journal Article] Fibrosis Staging Using Direct Serum Biomarkers is Influenced by Hepatitis Activity Grading in Hepatitis C Virus Infection.2018
- Author(s)
  Fujita K, Kuroda N, Morishita A, Oura K, Tadokoro T, Nomura T, Yoneyama H, Arai T, Himoto T, Watanabe S, Masaki T.
- Journal Title
  
  J Clin Med
  
  Volume: 7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients.2018
- Author(s)
  Fujita K, Mimura S, Iwama H, Nakahara M, Oura K, Tadokoro T, Nomura T, Tani J, Yoneyama H, Morishita A, Oryu M, Himoto T, Nishitsuji H, Shimotohno K, Omata M, Masaki T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19(7)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] MicroRNAs as possible biomarkers for hepatocellular carcinoma.2018
- Author(s)
  Morishita A, Masaki T.
- Journal Title
  
  Hepatol Res
  
  Volume: 48 Pages: 499-501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9 ameliorates fulminant liver injury.2017
- Author(s)
  Tadokoro T, Morishita A, Sakamoto T, Fujihara S, Fujita K, Mimura S, Oura K, Nomura T, Tani J, Yoneyama H, Iwama H, Himoto T, Niki T, Hirashima M, Masaki T
- Journal Title
  
  Mol Med Rep
  
  Volume: 16(1) Issue: 1 Pages: 36-42
- DOI
  10.3892/mmr.2017.6606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Therapeutic potential of the antidiabetic drug metformin in small bowel adenocarcinoma.2017
- Author(s)
  Chiyo T, Kato K, Iwama H, Fujihara S, Fujita K, Tadokoro T, Ohura K, Samukawa E, Yamana Y, Kobayashi N, Matsunaga T, Nishiyama N, Ayaki M, Yachida T, Morishita A, Kobara H, Mori H, Masaki T.
- Journal Title
  
  Int J Oncol
  
  Volume: 50(6) Issue: 6 Pages: 2145-2153
- DOI
  10.3892/ijo.2017.3971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] icroRNA profile of hepatic epithelioid hemangioendothelioma: A case report.2017
- Author(s)
  Morishita A, Iwama H, Yoneyama H, Sakamoto T, Fujita K, Nomura T, Tani J, Miyoshi H, Fujihara S, Nishiyama N, Kobara H, Mori H, Yamamoto N, Okano K, Suzuki Y, Ibuki E, Haba R, Himoto T, Masaki T.
- Journal Title
  
  Oncol Lett
  
  Volume: 13(3) Issue: 3 Pages: 1655-1659
- DOI
  10.3892/ol.2017.5643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells.2017
- Author(s)
  Akashi E, Fujihara S, Morishita A, Tadokoro T, Chiyo T, Fujikawa K, Kobara H, Mori H, Iwama H, Okano K, Suzuki Y, Niki T, Hirashima M, Masaki T.
- Journal Title
  
  Oncol Rep
  
  Volume: 38(1) Issue: 1 Pages: 506-514
- DOI
  10.3892/or.2017.5689
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9: An anticancer molecule for gallbladder carcinoma.2016
- Author(s)
  Tadokoro T, Morishita A, Fujihara S, Iwama H, Niki T, Fujita K, Akashi E, Mimura S, Oura K, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Himoto T, Hirashima M, Masaki T.
- Journal Title
  
  Int J Oncol
  
  Volume: 48 Issue: 3 Pages: 1165-1174
- DOI
  10.3892/ijo.2016.3347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9 suppresses the proliferation of gastric cancer cells in vitro.2016
- Author(s)
  Takano J, Morishita A, Fujihara S, Iwama H, Kokado F, Fujikawa K, Fujita K, Chiyo T, Tadokoro T, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Mori H, Niki T, Hirashima M, Masaki T.
- Journal Title
  
  Oncol Rep
  
  Volume: 35 Issue: 2 Pages: 851-860
- DOI
  10.3892/or.2015.4452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
[Presentation] Lenvatinib, Sorafenib 耐性肝細胞癌における緑茶に含まれるエピガロカテキンガレートの抗腫瘍効果の基礎的検討2023
- Author(s)
  北岡陸男、藤田浩二、中原麻衣、大浦杏子、田所智子、谷丈二、森下朝洋、正木勉
- Organizer
  第27回肝臓学会大会
- Data Source
  KAKENHI-PROJECT-22K08078
[Presentation] 非アルコール性脂肪性肝炎進展に関与するマクロファージを制御するターゲットマイクロRNAの同定2023
- Author(s)
  森下朝洋
- Organizer
  第59回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K07825
[Presentation] マクロファージ制御による非アルコール性脂肪性肝炎進展の抑制効果2022
- Author(s)
  森下　朝洋
- Organizer
  第26回日本肝臓学会大会（JDDW2022）
- Data Source
  KAKENHI-PROJECT-20K07825
[Presentation] 非アルコール性脂肪性肝炎進展における細胞間相互作用の細胞生物学的解析2022
- Author(s)
  森下　朝洋
- Organizer
  第44回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-20K07825
[Presentation] 微小環境からみたNASH発癌に関与するマクロファージの役割2021
- Author(s)
  森下朝洋
- Organizer
  第44回日本肝臓学会西部会2021
- Data Source
  KAKENHI-PROJECT-20K07825
[Presentation] 食道腺癌におけるガレクチン9の増殖抑制効果の検討2018
- Author(s)
  明石瑛美子、藤原新太郎、森下朝洋、田所智子、千代大翔、正木　勉
- Organizer
  第60回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] miR-762はDAA治療経過中のゲノタイプ1型HCV排除に際して血清中に増加する2018
- Author(s)
  米山弘人、森下朝洋、藤田浩二、野村貴子、坂本鉄平、田所智子、大浦杏子、谷　丈二、出口章広、樋本尚志、三村志麻、正木　勉
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] ソラフェニブ抵抗性肝細胞癌に対する新規治療薬としてのマイクロRNAの有効性2018
- Author(s)
  森下朝洋、谷　丈二、正木　勉
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] C型肝炎起因性肝細胞癌におけるバイオマーカーとしての血清miR-125a-5pの有用性2018
- Author(s)
  大浦杏子、田所智子、藤田浩二、三村志麻、坂本鉄平、野村貴子、森下朝洋、米山弘人、正木　勉
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] Galectin-9による食道扁平上皮癌のアポトーシスの誘導と作用機序2017
- Author(s)
  千代大翔、藤原新太郎、森下朝洋、藤田浩二、山名佳美、大浦杏子、寒川英里、田所智子、小林伸也、松永多恵、西山典子、綾木麻紀、谷内田達夫、小原英幹、森　宏仁、正木　勉
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] Nonalcoholic Steatohepatitis(NASH)進展および発癌抑制に対するGalectin-9の有効性と機序についての検討2017
- Author(s)
  森下朝洋、田所智子、正木　勉
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] Serum Concentration of Galectin-9 Correlates to Liver Fibrosis.2017
- Author(s)
  Fujita K, Morishita A, Yoneyama H, Niki T, Nishimoto N, Himoto T, Masaki T.
- Organizer
  APASL STC 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09361

1. Masaki Tsutomu (30335848)

# of Collaborated Projects: 9 results

# of Collaborated Products: 16 results
2. Fujita Koji (50749421)

# of Collaborated Projects: 7 results

# of Collaborated Products: 10 results
3. Kobara Hideki (10612476)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. IWAMA Hisakazu (20398035)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
5. Nomura Takako (70645415)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
6. 米山弘人 (80294750)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
7. 谷丈二 (00596075)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
8. 森宏仁 (20568844)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
9. 坂本鉄平 (30769328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 仁木敏朗 (40558508)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. 田所智子 (50813177)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. 大浦杏子 (80834639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. 藤原新太郎 (30612486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 大森典子 (50613410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中原麻衣 (00865610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Morishita Asahiro 森下 朝洋

森下 朝洋 モリシタ アサヒロ

Research Projects

Research Products

Co-Researchers

非アルコール性脂肪性肝炎由来肝細胞癌に対する免疫化学療法の治療抵抗性の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of the effect of combination therapy of galectin-9 and epigallocatechin gallate on hepatocellular carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非アルコール性脂肪性肝炎進展を抑制するマクロファージを用いた新しい細胞治療Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anti-tumor effect of Galectin-9 on metastatic hepatocellular carcinoma and its microRNA basis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prediction of prognosis targeting microRNAs in exosomes in primary biliary cholangitis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of microRNAs that regulate Galectin 9 to suppress nonalcoholic steatohepatitis progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of miR-301a in aging, metabolic syndrome and carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study on treatment of hepatocellular carcinoma targetted of Gal-9 exosomes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of pathway and prognostic factor prediction derived from microRNA analysis in gastrointestinal submucosal tumor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

正常大腸粘膜および大腸癌におけるプロテオーム解析と癌特異的タンパク質の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Can microRNA-96-5p serve as a therapeutic molecule in the near future?2022

Author(s)

Journal Title

Data Source

[Journal Article] Fibrosis Staging Using Direct Serum Biomarkers is Influenced by Hepatitis Activity Grading in Hepatitis C Virus Infection.2018

Author(s)

Journal Title

Data Source

[Journal Article] Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients.2018

Author(s)

Journal Title

Data Source

[Journal Article] MicroRNAs as possible biomarkers for hepatocellular carcinoma.2018

Author(s)

Journal Title

Morishita Asahiro 森下朝洋

森下朝洋モリシタアサヒロ