komeda seiji 米田誠治

… Alternative Names

Komeda Seiji 米田誠治

KOMEDA Seiji 米田誠治

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Researcher Number	60425056
Other IDs
Affiliation (Current)	2025: 鈴鹿医療科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 鈴鹿医療科学大学, 薬学部, 教授 2019: 鈴鹿医療科学大学, 薬学部, 准教授 2013 – 2017: 鈴鹿医療科学大学, 薬学部, 准教授 2012: 鈴鹿医療科学大学, 薬学部, 助教 2010: Suzuka University of Medical Science, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Physical pharmacy / Chemistry related to living body Except Principal Investigator Medium-sized Section 34:Inorganic/coordination chemistry, analytical chemistry, and related fields / Physical pharmacy
Keywords	Principal Investigator 金属錯体 / DDS / がん / 核酸 / 白金 / DNA / 制がん剤 / 白金錯体 / 免疫 / 抗腫瘍効果 … More / 白金製剤 / 創薬 / 薬物耐性 / シスプラチン / ナノ粒子 / アルブミン / プロテオミクス / EPR / 細胞内取込 / 白金制がん剤 / 細胞内蓄積 / 大腸がん / オキサリプラチン / 難治性がん / アゾール / テトラゾール / X線結晶解 / X線結晶解析 … More Except Principal Investigator 一電子酸化 / アンモニア生成 / モリブデン窒素錯体 / N≡N結合の酸化的切断 / 窒素活性化 / 非共有結合性相互作用 / 複核錯体 / シスプラチン / 白金錯体 / 複核白金錯体 / 分子認識 / 物理系薬学 / 抗がん剤 / 核酸 Less

窒素の三重結合をマイルドな酸化剤で切断しアンモニアに変換する革新的反応システム
- Principal Investigator
  
  増田秀樹
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 34:Inorganic/coordination chemistry, analytical chemistry, and related fields
- Research Institution
  Suzuka University of Medical Science
白金二核錯体の免疫賦活作用機序の解明とDDS化Principal Investigator
- Principal Investigator
  
  米田誠治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Suzuka University of Medical Science
Development of a next-generation platinum-based drug with a markedly high and long-lasting antitumor efficacyPrincipal Investigator
- Principal Investigator
  
  Komeda Seiji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Suzuka University of Medical Science
Drug discovery research based on dinuclear platinum complexes with markedly high antitumor activityPrincipal Investigator
- Principal Investigator
  
  Komeda Seiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Suzuka University of Medical Science
Development of next-generation anticancer drugs using dinuclear transition metal complexesPrincipal Investigator
- Principal Investigator
  
  KOMEDA Seiji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Suzuka University of Medical Science
Development of anticancer platinum complexes that recognize a specific region of nucleic acid.Principal Investigator
- Principal Investigator
  
  KOMEDA Seiji, 米田誠治
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Suzuka University of Medical Science
Multiple Recognition of DNA by dinuclear platinum complexes with effective cell growth inhibition in cisplatin resistant cell lines
- Principal Investigator
  
  CHIKUMA Masahiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences

[Book] パートナー分析化学II 改訂第３版2017
- Author(s)
  能田均、萩中淳、山口政俊、水野初、本間浩、米田誠治、山下幸和、北村陽二、黒沢隆夫、明樂一己、藤岡稔弘、石濱泰、大江知行、眞野成康、吉田秀幸　巴山忠、寺西正憲、金田典雄、畑中保丸、友廣岳則　他
- Total Pages
  332
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15K07905
[Journal Article] Introduction of Fluorine into Antitumor-Active Dinuclear Platinum(II) Complexes Leads to Modulation of In Vivo Antitumor Activity in Mice2022
- Author(s)
  Uemura M., Hiramoto K., Yoneyama H., Harusawa S., Komeda S.
- Journal Title
  
  Inorganic Chemistry
  
  Volume: 61 Issue: 31 Pages: 12155-12164
- DOI
  10.1021/acs.inorgchem.2c01126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16340, KAKENHI-PROJECT-19K07018
[Journal Article] Data on synthesis and structure?activity relationships of tetrazolato-bridged dinuclear platinum(II) complexes2022
- Author(s)
  Komeda Seiji、Yoneyama Hiroki、Uemura Masako、Tsuchiya Takahiro、Hoshiyama Miyuu、Sakazaki Tomoya、Hiramoto Keiichi、Harusawa Shinya
- Journal Title
  
  Data in Brief
  
  Volume: 40 Pages: 107697-107708
- DOI
  10.1016/j.dib.2021.107697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16340, KAKENHI-PROJECT-19K07018
[Journal Article] 創薬分野における白金と白金族元素2021
- Author(s)
  米田誠治
- Journal Title
  
  金属
  
  Volume: 1220 Pages: 758-762
- Data Source
  KAKENHI-PROJECT-19K07018
[Journal Article] Different Effects of Cisplatin and Transplatin on the Higher-Order Structure of DNA and Gene Expression2019
- Author(s)
  Kishimoto Toshifumi、Yoshikawa Yuko、Yoshikawa Kenichi、Komeda Seiji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 1 Pages: 34-34
- DOI
  10.3390/ijms21010034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02121, KAKENHI-PROJECT-19K07018
[Journal Article] Associative intraligand substitution of anticancer azolato-bridged compounds without a square-pyramidal intermediate: Formation of a unique tetranuclear, μ3-1,2,3-triazolato-N1,N2,N3-bridged Pt(II) compound2019
- Author(s)
  Komeda Seiji、In Yasuko、Tomoo Koji、Minoura Katsuhiko、Sato Takaji、Reedijk Jan、Ishida Toshimasa、Chikuma Masahiko
- Journal Title
  
  Inorganica Chimica Acta
  
  Volume: 495 Pages: 118999-118999
- DOI
  10.1016/j.ica.2019.118999
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07018
[Journal Article] Specific Conformational Change in Giant DNA Caused by Anticancer2017
- Author(s)
  S. Komeda, H. Yoneyama, M. Uemura, A. Muramatsu, N. Okamoto,
- Journal Title
  
  Inorg. Chem.
  
  Volume: 56 Issue: 2 Pages: 802-811
- DOI
  10.1021/acs.inorgchem.6b02239
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460160, KAKENHI-PROJECT-15K07905, KAKENHI-PLANNED-25103012
[Journal Article] Conformational transition of DNA by dinuclear Pt(II) complexes causes cooperative inhibition of gene expression2017
- Author(s)
  Shimizu, Y.; Yoshikawa, Y.; Kenmotsu, T.; Komeda, S.; Yoshikawa, K.
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 678 Pages: 123-129
- DOI
  10.1016/j.cplett.2017.04.039
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07905, KAKENHI-PROJECT-15H02121
[Journal Article] Kinetic analysis of and platinum(II) migration in the reactions of tetrazolato-bridged dinuclear platinum(II) complexes with nucleotides.2017
- Author(s)
  Uemura M., Komeda S.
- Journal Title
  
  J Inorg Biochem.
  
  Volume: 177 Pages: 359-367
- DOI
  10.1016/j.jinorgbio.2017.08.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15436, KAKENHI-PROJECT-15K07905
[Journal Article] The phosphate clamp as recognition motif in platinum-DNA interactions2016
- Author(s)
  Komeda, S.; Qu, Y.; Mangrum, J. B.; Hegmans, A.; Williams, L. D.; Farrell, N. P.
- Journal Title
  
  Inorganica Chimica Acta
  
  Volume: 81 Pages: 2399-2404
- DOI
  10.1016/j.ica.2016.04.052
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07905
[Journal Article] Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex.2016
- Author(s)
  Imai R, Komeda S, Shimura M, Tamura S, Matsuyama S, Nishimura K, Rogge R, Matsunaga A, Hiratani I, Takata H, Uemura M, Iida Y, Yoshikawa Y, Hansen JC, Yamauchi K, Kanemaki MT, Maeshima K.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 24712-24725
- DOI
  10.1038/srep24712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07905, KAKENHI-PROJECT-16K15095, KAKENHI-PROJECT-16H04746
[Journal Article] Highly efficient uptake into cisplatin-resistant cells and the isomerization upon coordinative DNA binding of anticancer tetrazolato-bridged dinuclear platinum(II) complexes.2015
- Author(s)
  Uemura M, Hoshiyama M, Furukawa A, Sato T, Higuchi Y, Komeda S.
- Journal Title
  
  Metallomics
  
  Volume: 7 Issue: 11 Pages: 1488-1496
- DOI
  10.1039/c5mt00174a
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07905
[Journal Article] Synthesis of antitumor azolato-bridged dinuclear platinum(ii) complexes with in vivo antitumor efficacy and unique in vitro cytotoxicity profiles2013
- Author(s)
  Komeda S, Takayama H, Suzuki T, Odani A, Yamori T, Chikuma M
- Journal Title
  
  Metallomics
  
  Volume: 5(5) Issue: 5 Pages: 461-468
- DOI
  10.1039/c3mt00040k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-24590063
[Journal Article] Second- and Higher-order Structural Changes of DNA Induced by Antitumor-Active Tetrazolato-Bridged Dinuclear Platinum(II) 　Complexes with Different Types of 5-Substituent.2013
- Author(s)
  Uemura, M.; Yoshikawa, Y.; Sato, T.; Mino, Y.; Yoshikawa, K.; Chikuma, M.; Komeda, S.
- Journal Title
  
  J Inorg Biochem
  
  Volume: 127 Pages: 169-174
- DOI
  10.1016/j.jinorgbio.2013.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590063
[Journal Article] DNA conformation and repair of polymeric natural DNA damaged by antitumor azolato-bridged dinuclear PtII complex.2012
- Author(s)
  Mlcouskova, J.; Kasparkova, J.; Suchankova, T.; Komeda, S.; Brabec, V.
- Journal Title
  
  J Inorg Biochem
  
  Volume: 114 Pages: 15-23
- DOI
  10.1016/j.jinorgbio.2012.04.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590063
[Journal Article] Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex.2012
- Author(s)
  Mlcouskova, J.; Malina J.; Novohradsky V.; Kasparkova J.; Komeda S.; Brabec V.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1820 Issue: 10 Pages: 1502-1511
- DOI
  10.1016/j.bbagen.2012.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590063
[Journal Article] An in vivo highly antitumor-active tetrazolato-bridged dinuclear platinum(ii) complex largely circumvents in vitro cisplatin resistance : two linkage isomers yield the same product upon reaction with 9-ethylguanine but exhibit different cytotoxic profiles2012
- Author(s)
  Uemura M, Suzuki T, Nishio K, Chikuma M, Komeda S.
- Journal Title
  
  Metallomics
  
  Volume: 4(in press) Issue: 7 Pages: 686-692
- DOI
  10.1039/c2mt20026k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790173, KAKENHI-PROJECT-24590063
[Journal Article] A circular cichroism study uncovers a two-step interaction of antitumor azolato-bridged dinuclear platinum(II) complexes with calf thymus DNA2012
- Author(s)
  Masako Uemura
- Journal Title
  
  Metallomics
  
  Volume: 4 Issue: 7 Pages: 641-644
- DOI
  10.1039/c2mt20022h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510123, KAKENHI-PROJECT-24590063
[Journal Article] The phosphate clamp : a small and independent motif for nucleic acid backbone recognition.2011
- Author(s)
  米田誠治
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 39 Pages: 325-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] Unique platinum-DNA interactions may lead to more effective platinum-based antitumor drugs.2011
- Author(s)
  米田誠治
- Journal Title
  
  Metallomics
  
  Volume: (Web公開)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] A tetrazolato-bridged dinuclear platinum(II)complex exhibits markedly high in vivo antitumor activity against pancreatic cancer.2011
- Author(s)
  米田誠治
- Journal Title
  
  ChemMedChem
  
  Volume: (Web公開)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] The phosphate clamp : A Small and independent motif for nucleic acid backbone recognition2011
- Author(s)
  Komeda S., Moulaei T., Chikuma M., Odani A., Kipping R., Farrell N.P., Williams L.D.
- Journal Title
  
  Nucleic Acids Res 39
  
  Pages: 325-36
- Data Source
  KAKENHI-PROJECT-20590045
[Journal Article] Unique platinum-DNA interactions may lead to more effective platinum-based antitumor drugs.2011
- Author(s)
  Komeda, S.
- Journal Title
  
  Metallomics Epub ahead of print.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] The phosphate clamp: a small and independent motif for nucleic acid backbone recognition.2011
- Author(s)
  Komeda, S., Moulaei, T., Chikuma, M., Odani, A., Kipping, R., Farrell, N.P., Williams, L.D.
- Journal Title
  
  Nucleic Acids Res. 39
  
  Pages: 325-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] The phosphate clamp : a small and independent motif for nucleic acid backbone recognition2011
- Author(s)
  Seiji Komeda
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 39 Pages: 325-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590045
[Journal Article] A tetrazolato-bridged dinuclear platinum(II) complex exhibits markedly high in vivo antitumor activity against pancreatic cancer2011
- Author(s)
  Komeda S., Lin Y-L., Chikuma M.
- Journal Title
  
  ChemMedChem 6
  
  Pages: 987-990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590045
[Journal Article] A tetrazolato-bridged dinuclear platinum(II) complex exhibits markedly high in vivo antitumor activity against pancreatic cancer.2011
- Author(s)
  Komeda, S., Lin, Y-L., Chikuma, M.
- Journal Title
  
  ChemMedChem 6
  
  Pages: 987-990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] Characteristic effect of an anticancer dinuclear platinum(II) complex on the higher-order structure of DNA.2010
- Author(s)
  Kida, N., Katsuda, Y., Yoshikawa, Y., Komeda, S., Sato, T., Saito, Y., Chikuma, M., Suzuki, M., Imanaka, T., Yoshikawa, K.
- Journal Title
  
  J.Biol.Inorg.Chem. 15
  
  Pages: 701-707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] 次世代白金制がん剤の創薬研究2010
- Author(s)
  米田誠治
- Journal Title
  
  日本化学会生体機能関連化学部会 NEWS LETTER 25
  
  Pages: 7-10
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] 次世代白金制がん剤の創薬研究2010
- Author(s)
  米田誠治
- Journal Title
  
  社団法人日本化学会生体機能関連科学部会ニュースレター
  
  Volume: 25 Pages: 7-10
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] Application of anomalous diffraction methods to the study of DNA and DNA-complexes.2010
- Author(s)
  Watkins, D., Moulaei, T., Komeda, S., Williams, L.D.
- Journal Title
  
  Methods in Mol.Biol. 613
  
  Pages: 133-152
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] A new class of rhodamine luminophores : design, syntheses and aggregation-induced emission enhancement.2010
- Author(s)
  Kamino, S., Horio, Y., Komeda, S., Minoura, K., Ichikawa, H., Horigome, J., Tatsumi, A., Kaji, S., Yamaguchi, T., Usami, Y., Hirota, S., Enomoto, S., Fujita Y.
- Journal Title
  
  Chem.Commun. 46
  
  Pages: 9013-9015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] Characteristic effect of anticancer dinuclear platinum(II) complex on the higher-order structure of DNA2009
- Author(s)
  Kida N., Katsuda Y., Yoshikawa Y., Komeda S., Sato T., Saito Y., Chikuma M., Suzuki M., Imanaka T., Yoshikawa K.
- Journal Title
  
  Journal of Bioinorganic Chemistry 15(5)
  
  Pages: 701-707
- Data Source
  KAKENHI-PROJECT-20590045
[Journal Article] Next-generation anticancer metallodrugs
- Author(s)
  Komeda, S., Casini, A.
- Journal Title
  
  Cuur.Top.Med.Chem. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750177
[Journal Article] Efficient Transformation of Inactive Nitriles into 5-Substituted-1H-tetrazoles Using Microwave Irradiation and Their Applications
- Author(s)
  H. Yoneyama
- Journal Title
  
  Synthesis
  
  Volume: 45 Issue: 08 Pages: 1051-1059
- DOI
  10.1055/s-0032-1318476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590130, KAKENHI-PROJECT-24590063
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Filing Date
  2010-07-24
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Filing Date
  2010-07-12
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Filing Date
  2010-07-14
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Filing Date
  2010-07-20
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Filing Date
  2010-07-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Filing Date
  2010-07-24
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Filing Date
  2010-07-14
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] 白金錯体化合物およびその利用2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Industrial Property Number
  2009-550001
- Filing Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Filing Date
  2010-07-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] 白金錯体化合物およびその利用2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Industrial Property Number
  2009-550001
- Filing Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-20590045
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Filing Date
  2010-08-05
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Filing Date
  2010-08-05
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] 白金錯体化合物およびその利用2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Industrial Property Number
  2009-550001
- Filing Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Filing Date
  2010-07-12
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Filing Date
  2010-07-20
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Filing Date
  2010-08-11
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] PLATINUM COMPLEX COMPOUND AND UTILIZATION OF THE SAME2010
- Inventor(s)
  米田誠治, 千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株), (株)ヤクルト本社
- Filing Date
  2010-08-11
- Overseas
- Data Source
  KAKENHI-PROJECT-21750177
[Patent] 白金錯体化合物およびその利用2010
- Inventor(s)
  米田誠治,千熊正彦
- Industrial Property Rights Holder
  天真堂製薬(株),(株)ヤクルト本社
- Industrial Property Number
  2009-550001
- Filing Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] 顕著な in vivo 抗腫瘍効果と優れた効果持続性を有するカチオン性白金(II)二核錯体2024
- Author(s)
  米田誠治
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06074
[Presentation] 抗がん活性を有するアゾラト架橋白金(II)二核錯体とアデノシンにより形成される新奇な8員環キレート錯体2024
- Author(s)
  山田拓磨、植村雅子、箕浦克彦、米田誠治
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06074
[Presentation] DNAのコアセルベートを誘導する白金錯体の探索2024
- Author(s)
  田代竜、山田拓磨、矢野芹佳、荒木礼子、西原大樹、中川萌、植村雅子、米田誠治
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K06074
[Presentation] oxaliplatin耐性大腸がん細胞に対する白金(II)二核錯体の細胞毒性評価2024
- Author(s)
  植村雅子、米山弘樹、宇佐美吉英、春沢信哉、米田誠治
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06074
[Presentation] アゾラト架橋白金(II)二核錯体を基盤とする創薬研究と新たな反応機構2023
- Author(s)
  山田拓磨、米田誠治
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2023
- Data Source
  KAKENHI-PROJECT-23K06074
[Presentation] 末端アルキンを導入したテトラゾラト架橋白金(II)二核錯体の合成と細胞毒性2023
- Author(s)
  若山実希、米山弘樹、植村雅子、宇佐美吉英、米田誠治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] Influence of Transporters on Cellular Accumulation of Antitumor-active Dinuclear Platinum(II) Complex2023
- Author(s)
  植村雅子、米田誠治
- Organizer
  第32回金属の関与する生体関連反応シンポジウム
- Data Source
  KAKENHI-PROJECT-23K06074
[Presentation] 抗腫瘍活性を有する白金(II)二核錯体の細胞輸送におけるトランスポーターの関与2023
- Author(s)
  植村雅子、米田誠治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 制がん白金 (II)錯体とアデノシンの新たな反応機構2023
- Author(s)
  山田拓磨、米田誠治
- Organizer
  第34回生体機能関連化学部会若手の会サマースクール
- Data Source
  KAKENHI-PROJECT-23K06074
[Presentation] シスプラチン耐性がんに有効なアゾラト架橋白金(II)二核錯体とモノヌクレオチドの反応2023
- Author(s)
  山田拓磨、米田誠治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 核酸によって反応機構が異なる制がん白金二核錯体2023
- Author(s)
  山田拓磨、米田誠治
- Organizer
  第69回日本薬学会東海支部大会
- Data Source
  KAKENHI-PROJECT-23K06074
[Presentation] Antitumor and immunostimulatory activities of the tetrazolato-bridged dinuclear Pt(II) complexes2022
- Author(s)
  Komeda Seiji、Hiramoto Keiichi、Uemura Masako、Yoneyama Hiroki、Usami Yoshihide、Harusawa Shinya
- Organizer
  10th Asian Biological Inorganic Chemistry Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] In vitro and in vivo activity of fluoromethyl group-introduced antitumor-active dinuclear platinum(II) complex2022
- Author(s)
  Uemura Masako、Hiramoto Keiichi、Yoneyama Hiroki、Usami Yoshihide、Harusawa Shinya、Komeda Seiji
- Organizer
  The 8th International Symposium on Metallomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] Tetrazolato-bridged dinuclear Pt(II) complexes and their potential applications in cancer chemotherapy2022
- Author(s)
  Komeda Seiji、Uemura Masako、Hiramoto Keiichi
- Organizer
  The 8th International Symposium on Metallomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 抗腫瘍効果を発揮するテトラゾラト架橋白金(II)二核錯体の開発研究2022
- Author(s)
  植村雅子、米田誠治
- Organizer
  第33回日本微量元素学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] In vivo anticancer efficacy and X-ray crystal structure of the tetrazolato-bridged dinuclear Pt(II) complex2022
- Author(s)
  Yamada Takuma、Hiramoto Keiichi、Uemura Masako、Komeda Seiji
- Organizer
  10th Asian Biological Inorganic Chemistry Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] Synthesis and characterization of tetrazolato-bridged dinuclear platinum(II) complexes with terminal alkynes2022
- Author(s)
  若山実希、米山弘樹、植村雅子、宇佐美吉英、春沢信哉、米田誠治
- Organizer
  第31回金属の関与する生体関連反応シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] プラチナを用いた費用対効果に優れた制がん剤の開発2022
- Author(s)
  米田誠治
- Organizer
  イノベーション・ジャパン2022
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 抗腫瘍活性を有する白金(II)二核錯体のoxaliplatin耐性大腸がんに対するin vitro活性評価2022
- Author(s)
  植村雅子、米田誠治
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 末端アルキンを導入したテトラゾラト架橋白金(II)二核錯体の合成と細胞毒性2022
- Author(s)
  若山実希、米山弘樹、植村雅子、宇佐美吉英、春沢信哉、米田誠治
- Organizer
  第68回日本薬学会東海支部大会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] Introduction of fluorine into antitumor-active dinuclear platinum(II) complex changes in vitro/in vivo activity2021
- Author(s)
  植村雅子、平本恵一、米山弘樹、宇佐美吉英、春沢信哉、米田誠治
- Organizer
  第30回金属の関与する生体関連反応シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 抗腫瘍活性を有する白金(II)二核錯体へのフッ素導入によるin vitro/in vivo活性の変化2021
- Author(s)
  植村雅子、平本恵一、米山弘樹、宇佐美吉英、春沢信哉、米田誠治
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] アゾラト架橋白金(II)二核錯体によるアンドロゲン受容体を介したヒト前立腺がん細胞に対する細胞増殖抑制効果の検討2021
- Author(s)
  新井佑、鎌尾まや、米田誠治、廣田佳久
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] Next-Generation Platinum-Based Drug2020
- Author(s)
  Seiji Komeda
- Organizer
  Innovation Lecture at Masaryk University supported by Ministry of Education, Youth and Sports
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 「型破りな」制がん白金錯体のin vivo 抗腫瘍効果2020
- Author(s)
  米田誠治、植村雅子、平本恵一
- Organizer
  生命金属に関する合同年会（ConMetal 2020）
- Invited
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 含フッ素白金(II)二核錯体のマウス大腸がんにおける細胞内蓄積量とin vitroおよびin vivo活性評価2020
- Author(s)
  植村雅子、平本恵一、米山弘樹、宇佐美吉英、春沢信哉、米田誠治
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] A Modification at Tetrazole C5 Markedly Influences the In Vivo Antitumor Efficacy of Tetrazolato-Bridged Dinuclear Pt(II) Complexes2019
- Author(s)
  Seiji Komeda
- Organizer
  15th International Symposium on Applied Bioinorganic Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] In Vitro Cytotoxicity and In Vivo Antitumor Efficacy of Tetrazolato-Bridged Dinuclear Platinum(II) Complexes with a Bulky Substituent at Tetrazole C52019
- Author(s)
  Masako Uemura、Keiichi Hiramoto、Hiroki Yoneyama、Shinya Harusawa、Seiji Komeda
- Organizer
  15th International Symposium on Applied Bioinorganic Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] 新奇なプラチナ錯体でがんは完全に治る?2019
- Author(s)
  米田誠治
- Organizer
  イノベーション・ジャパン2019 ～大学見本市＆ビジネスマッチング～
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] Development of Next-Generation Platinum-Based Drug with Markedly High and Long-Lasting Antitumor Efficacy2019
- Author(s)
  Seiji Komeda、Masako Uemura、Keiichi Hiramoto
- Organizer
  第29回金属の関与する生体関連反応シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07018
[Presentation] メチル基を有するテトラゾラト架橋白金(II)二核錯体のDNAとの相互作用および細胞内取り込みにおけるフッ素導入効果の検討2018
- Author(s)
  植村雅子，米山弘樹，春沢信哉，米田誠治
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 顕著な抗腫瘍効果を有する白金(II)二核錯体のユニークな作用機構2017
- Author(s)
  植村雅子、米田誠治、吉川研一、吉川祐子、春沢信哉、米山弘樹
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] DNA interaction and structure-activity telationship of tetrazolato-bridged dinuclear platinum(II) complexes with fluoromethyl group2017
- Author(s)
  植村雅子，米山弘樹，坂﨑智哉，長江紀樹，小井阪あゆみ，春沢信哉，米田誠治
- Organizer
  第27回金属の関与する生体関連反応シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 制がん白金(II)二核錯体のDNA凝縮能および細胞内取り込みに関する研究2017
- Author(s)
  植村雅子, 米山弘樹, 岡本直人, 村松晃, 福田青郎, 小西宏明, 髙木陽光, 松﨑健, 春沢信哉, 吉川祐子, 今中忠行, 吉川研一，米田誠治
- Organizer
  第63回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Structure-activity relationships, DNA compaction efficiencies and intracellular accumulations on anticancer-active tetrazolato-bridged dinuclear platinum(II) complexes2017
- Author(s)
  Komeda, S.; Uemura, M.; Hiramoto, K.; Yoshikawa, Y.; Yoshikawa, K.; Yoneyama, H.; Harusawa, S.
- Organizer
  14th International Symposium on Applied Bioinorganic Chemistry
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Antitumor evaluation and DNA-binding property of tetrazolatobridged dinuclear platinum(II) complexes2017
- Author(s)
  Komeda, S.
- Organizer
  12th International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] DNA interactions and structure-activity relationship of tetrazolato-bridged dinuclear platinum(II) complexes with methyl and fluoromethyl group2017
- Author(s)
  Uemura, M.; Yoneyama, H.; Harusawa, S.; Komeda, S.
- Organizer
  12th International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 顕著なin vivo抗腫瘍効果を発揮するテトラゾラト架橋白金(II)二核錯体2017
- Author(s)
  米田誠治
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2017
- Invited
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Covalent interaction of anticancer azolato-bridged dinuclear platinum(II) complexes with nucleotide and double-helical DNA2016
- Author(s)
  Uemura, M.; Komeda, S.
- Organizer
  金属の関与する生体関連反応シンポジウム (SRM2016)
- Place of Presentation
  札幌市
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 長短鎖アルキル基を導入した制がんテトラゾラト架橋白金(II)二核錯体の細胞内取込およびDNA凝縮能2016
- Author(s)
  米田誠治, 植村雅子, 米山弘樹, 岡本直人, 村松晃, 福田青郎, 小西宏明, 髙木陽光, 松﨑健, 春沢信哉, 吉川祐子, 今中忠行, 吉川研一
- Organizer
  日本薬学会第136年会横浜市年月日201603-201603
- Place of Presentation
  横浜市
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Structure-activity relationships and DNA compaction efficiencies of anticancer tetrazolato-bridged dinuclear platinum(II) complexes2016
- Author(s)
  Komeda, S.
- Organizer
  8th Asian Biological Inorganic Chemistry Conference
- Place of Presentation
  ニュージーランド　オークランド
- Year and Date
  2016-12-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Biological efficiency of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with different length of alkyl substituent in relation to the structural effect of DNA2016
- Author(s)
  Komeda, S.; Uemura, M.; Yoneyama, H.; Muramatsu, A.; Okamoto, N.; Harusawa, S.; Yoshikawa, Y.; Yoshikawa, K.
- Organizer
  金属の関与する生体関連反応シンポジウム (SRM2016)
- Place of Presentation
  札幌市
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Significant effect of dinuclear Pt(II) complexes on the higher-order structure of genomic DNA2016
- Author(s)
  Shimizu, Y.; Yoshikawa, Y.; Uemura, M.; Kenmotsu, T.; Komeda, S.; Yoshikawa, K.
- Organizer
  8th Asian Biological Inorganic Chemistry Conference
- Place of Presentation
  ニュージーランド　オークランド
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Action of novel anticancer-active, dinuclear platinum complexes with ester group on the higher order structure and genomic activity of DNA2015
- Author(s)
  Shimizu, Y; Yoshikawa, Y; TaTsuchiya, T; Hiroki Yoneyama, H; Harusawa, S; Komeda, S; Imanaka, T; Kenmotsu, T; Yoshikawa, K.
- Organizer
  第53回生物物理学会日本薬学会
- Place of Presentation
  金沢市
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Azolato-bridged dinuclear platinum(II) complexes with markedly high in vivo antitumor efficacy against pancreatic cancer and unique in vitro cytotoxicity profiles2015
- Author(s)
  Seiji Komeda
- Organizer
  1st International Symposium on Clinical and Experimental Metallodrugs in Medicine: Cancer Chemotherapy
- Place of Presentation
  米国ハワイ州
- Year and Date
  2015-12-13
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015
- Author(s)
  Uemura, M; Yoneyama, H; Yoshikawa, T; Tsuchiya, T; Hoshiyama, M; Sato, T; Yoshikawa, K; Harusawa, S; Komeda, S
- Organizer
  第25回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  長崎市
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015
- Author(s)
  Uemura, M; Yoneyama, H; Yoshikawa, T; Tsuchiya, T; Hoshiyama, M; Sato, T; Yoshikawa, K; Harusawa, S; Komeda, S
- Organizer
  1st International Symposium on Clinical and Experimental Metallodrugs in Medicine: Cancer Chemotherapy
- Place of Presentation
  米国ハワイ州
- Year and Date
  2015-12-13
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 遷移金属二核錯体を用いた次世代制がん剤の開発2015
- Author(s)
  米田誠治
- Organizer
  三重大学・鈴鹿医療科学大学　合同産学官交流フォーラム
- Place of Presentation
  津市
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 白金およびルテニウム錯体とがん治療2014
- Author(s)
  米田誠治
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市
- Invited
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] 新規制がんテトラゾラト架橋白金(II)二核錯体の合成、細胞毒性およびDNAとの相互作用2013
- Author(s)
  米田誠治，岡本直人，植村雅子，米山弘樹，春沢信哉，小西宏明，高木陽光，松崎健
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] テトラゾール5位にエステル基を導入した制がん白金(II)二核錯体の合成およびin vitro 細胞毒性2013
- Author(s)
  土屋考弘，米山弘樹，春沢信哉，小西宏明，髙木陽光，松﨑健，植村雅子，米田誠治
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] テトラゾール5位に飽和アルキル基を導入した制がん白金(II)二核錯体のDNAとの相互作用2013
- Author(s)
  岡本直人，植村雅子，米山弘樹，春沢信哉，小西宏明，髙木陽光，松﨑健，吉川祐子，今中忠行，吉川研一，米田誠治
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] Second- and higher-order structural changes of DNA induced by antitumor-active 5-alkyl-tetrazolato-bridged dinuclear platinum(II) complexes2013
- Author(s)
  植村雅子，岡本直人，米山弘樹，春沢信哉，吉川研一，吉川祐子，今中忠行，小西宏明，髙木陽光，松﨑健，千熊正彦，米田誠治
- Organizer
  第23回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  西東京市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] プロテオミクスを用いた制がん白金錯体5-H-Yによるタンパク質発現変動解析2013
- Author(s)
  佐藤誠泰，古川絢子，植村雅子，樋口善弘，米田誠治
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] A circular dichroism study on the activity of antitumor- active tetrazolato-bridged dinuclear Pt(II) complex derivatives to change secondary structure of DNA2012
- Author(s)
  Uemura, M.; Chikuma, M.; Komeda, S.
- Organizer
  11th European Biological Inorganic Chemistry Conference
- Place of Presentation
  スペイン　グラナダ市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] DNA Conformational Changes Induced by Antitumor Tetrazolato-Bridged Dinuclear Pt(II) Complexes2012
- Author(s)
  植村雅子，藤澤豊，定金豊，飯田靖彦，森井孫俊，千熊正彦，米田誠治
- Organizer
  第22回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] 新規テトラゾラト架橋白金（II）二核錯体の合成、細胞毒性およびDNA との相互作用2012
- Author(s)
  岡本直人，植村雅子，米山弘樹，春沢信哉，小西宏明，高木陽光，松崎健，米田誠治
- Organizer
  第3回メタロミクス研究フォーラム
- Place of Presentation
  町田市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] 制がん活性を有するテトラゾラト架橋白金(II)二核錯体によるDNAの濃度および時間依存的二次構造変化2012
- Author(s)
  植村雅子，千熊正彦，米田誠治
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] 次世代白金制がん剤の創薬研究2012
- Author(s)
  米田誠治
- Organizer
  第25回生物無機化学夏季セミナー
- Place of Presentation
  郡上市
- Invited
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] Synthesis, biological evaluation and DNA interaction of the series of antitumor azolato-bridged dinuclear platinum(II) complexes2012
- Author(s)
  Komeda, S.; Uemura, M.; Yoshikawa, Y. Chikuma, M.; Yamori, T.
- Organizer
  11th European Biological Inorganic Chemistry Conference
- Place of Presentation
  スペイン　グラナダ市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] In vivo 制がん活性を有するアゾラト架橋白金(II)二核錯体の創薬研究2012
- Author(s)
  米田誠治，植村雅子，吉川祐子，千熊正彦，矢守隆夫
- Organizer
  錯体化学会第62回討論会
- Place of Presentation
  富山市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] In vivo highly antitumor- active tetrazolato-bridged dinuclear platinum(II) complexes2012
- Author(s)
  米田誠治，植村雅子，吉川祐子，千熊正彦，矢守隆夫
- Organizer
  第22回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] より有用な白金制がん剤を求めて2012
- Author(s)
  米田誠治
- Organizer
  第43回中部化学関係学協会支部連合秋季大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] in vivo制がん活性を有する白金(II)複核錯体と核酸との相互作用様式2011
- Author(s)
  米田誠治
- Organizer
  日本薬学会第131年会
- Place of Presentation
  コンベンションアーツセンター「グランシップ」(静岡県静岡市)
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] アゾラト架橋白金(II)二核錯体とDNAの相互作用様式に関する研究2011
- Author(s)
  植村雅子, 藤澤豊, 飯田靖彦, 森井孫俊, 桜井弘, 千熊正彦, 米田誠治
- Organizer
  日本薬学会第131年会
- Place of Presentation
  コンペンションアーツセンター「グランシップ」(静岡市)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] In vivo 制がん活性を有する白金(II)複核錯体と核酸との相互作用様式2011
- Author(s)
  米田誠治
- Organizer
  日本薬学会第131年会
- Place of Presentation
  コンペンションアーツセンター「グランシソプ」(静岡市)
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] アゾラト架橋白金(II)二核錯体とDNAの相互作用様式に関する研究2011
- Author(s)
  米田誠治
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] 制がん活性を有する白金(II)複核錯体と核酸との相互作用2010
- Author(s)
  米田誠治
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  豊中市
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] 制がん活性を有するアゾラト架橋白金(II)二核錯体2010
- Author(s)
  米田誠治, Yuh-ling Lin., 鈴木俊宏, 植村雅子, 千熊正彦
- Organizer
  第2回メタロミクス研究フォーラム
- Place of Presentation
  京都薬科大学(京都市)
- Year and Date
  2010-11-30
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 制がん活性を有するテトラゾレート架橋白金(II)二核錯体の核酸塩基との相互作用様式に関する研究2010
- Author(s)
  植村雅子, 藤澤豊, 飯田靖彦, 森井孫俊, 桜井弘, 千熊正彦, 米田誠治
- Organizer
  日本薬学会第130年会
- Place of Presentation
  桃太郎アリーナ(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 制がん活性を有する白金(II)複核錯体と核酸との相互作用2010
- Author(s)
  米田誠治, Yuh-Ling Lin, 鈴木俊宏, 植村雅子, Nicholas P.Farrell, Loren D.Williams, 小谷明, 千熊正彦
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪大学豊中キャンパス(大阪府豊中市)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] トリアゾール配位子を有する陽電荷白金二核錯体がDNAの高次構造に与える影響2010
- Author(s)
  木田直子, 勝田陽介, 吉川祐子, 米田誠治, 佐藤卓史, 斉藤睦弘, 千熊正彦, 鈴木麻里, 今中忠行, 吉川研一
- Organizer
  日本薬学会第130年会
- Place of Presentation
  桃太郎アリーナ(岡山市)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] DNA interactions of anticancer polynuclear Pt(II)complexes2010
- Author(s)
  米田誠治
- Organizer
  2010環太平洋国際化学会議(PACIFICHEM 2010)
- Place of Presentation
  ハワイコンベンションセンター(米国ハワイ州ホノルル)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] Interaction of anticancer active tetrazolato-bridged dinuclear platinum(II) complexes with a nucleobase2010
- Author(s)
  米田誠治
- Organizer
  第20回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] Interactions of anpcancer-active tetrazolato-bridged dinuclear pladnum(II) complexes with a nucleobase.2010
- Author(s)
  植村雅子, 藤澤豊, 飯田靖彦, 森井孫俊, 櫻井弘, 千熊正彦, 米田誠治
- Organizer
  第20回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  徳島文理大学薬学部(徳島市)
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 制がん活性を有するアゾラト架橋白金(II)二核錯体2010
- Author(s)
  米田誠治
- Organizer
  第2回メタロミクス研究フォーラム
- Place of Presentation
  京都薬科大学(京都市山科区)
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] DNA interactions of anticancer polynuclear Pt(II)complexes2010
- Author(s)
  Komeda, S., Chikuma, M., Farrell, N.P., Williams, LD.
- Organizer
  2010環太平洋国際化学会議
- Place of Presentation
  ハワイコンベンションセンター(米国ハワイ州ホノルル)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] X-ray crystallographic studies on DNA adduct formation by the anticancer-active polynuclear Pt(II) complexes2009
- Author(s)
  米田誠治
- Organizer
  The 2^<nd> Int.Symp.Bioinorg.Chem.of New Era
- Place of Presentation
  Takayama
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] 制がん活性を有するカチオン性白金(II)複核錯体のDNAとの相互作用様式2009
- Author(s)
  米田誠治, Nicholas P.Farrell, Loren D.Williams, 小谷明, 千熊正彦
- Organizer
  第55回日本薬学会東海支部
- Place of Presentation
  愛知学院大学薬学部(名古屋市)
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 制がん活性を有するカチオン性白金(II)複核錯体のDNAとの相互作用様式2009
- Author(s)
  米田誠治
- Organizer
  第55回日本薬学会東海支部大会
- Place of Presentation
  名古屋市
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] X-ray crystallographic studies on DNA adduct formation by the anticancer-active polynuclear Pt(II)complexes2009
- Author(s)
  Komeda, S., Odani, A., Chikuma, M., Farrell, N.P., Williams, L.D.
- Organizer
  The 2nd International Symposium on Biological Inorganic Chemistry ofthe New Era
- Place of Presentation
  高山コンベンションセンター(岐阜県高山市)
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 次世代白金制がん剤の開発研究2009
- Author(s)
  米田誠治
- Organizer
  大阪薬科大学ハイテクリサーチセンター平成21年度公開シンポジウム
- Place of Presentation
  大阪薬科大学(大阪府高槻市)
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 核酸の特定部位を認識する制がん白金錯体2009
- Author(s)
  米田誠治
- Organizer
  第24回生体機能関連化学シンポジウム
- Place of Presentation
  博多市
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] 次世代白金制がん剤の開発研究2009
- Author(s)
  米田誠治
- Organizer
  大阪薬科大学ハイテクリサーチセンター平成21年度公開シンポジウム
- Place of Presentation
  大阪薬科大学(大阪府)
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] X-ray crystallographic studies on DNA adduct formation by the anticancer-active polynuclear Pt(II)complexes2009
- Author(s)
  米田誠治
- Organizer
  The 2nd International Symposium on Biological Inorganic Chemistry of the New Era
- Place of Presentation
  高山コンベンションセンター(岐阜県)
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 制がん活性を有するカチオン性白金(II)複核錯体のDNAとの相互作用様式2009
- Author(s)
  米田誠治
- Organizer
  第55回日本薬学会東海支部
- Place of Presentation
  愛知学院大学薬学部(愛知県)
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 核酸の特定部位を認識する制がん白金錯体2009
- Author(s)
  米田誠治
- Organizer
  第24回生体機能関連化学部会シンポジウム
- Place of Presentation
  九州大学医学部百周年会館(福岡県)
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] 核酸の特定部位を認識する制がん白金錯体2009
- Author(s)
  米田誠治, Nicholas P.Farrell, Loren D.Willialns, 小谷明, 千熊正彦
- Organizer
  第24回生体機能関連化学部会シンポジウム
- Place of Presentation
  九州大学医学部百周年会館(福岡市)
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] Design, structure-activity relationships and x-ray co-crystallography of anticancer-active polynyclear platinum(II) complexes2009
- Author(s)
  Komeda, S., Odani, A., Chikuma, M., Farrell, N.P., Williams, L.D.
- Organizer
  14th International Conference on Biological Inorganic Chemistry
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] Design, structure-activity relationships and x-ray co-crystallography of anticancer-active polynyclear platinum(II)complexes2009
- Author(s)
  米田誠治
- Organizer
  14th International Conference on Biological Inorganic Chemistry
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-21750177
[Presentation] X-ray Crystallographic studies on DNA binding modes of polyamine-bridged polynuclear Pt(II) complexes2008
- Author(s)
  米田誠治
- Organizer
  9th European Biological Inorganic Chemistry Conference
- Place of Presentation
  Wroclaw, Poland
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] カチオン性制癌白金錯体のDNAとの相互作用様式2008
- Author(s)
  米田誠治
- Organizer
  第1回メタロミクス研究フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590045
[Presentation] 制がん tetrazolato 架橋白金(II)二核錯体の構造活性相関と細胞内取り込み
- Author(s)
  植村雅子，米山弘樹，土屋考弘，星山美有，古川絢子，樋口善博，佐藤卓史，春沢信哉，米田誠治
- Organizer
  第4回メタロミクス研究フォーラム
- Place of Presentation
  西東京市
- Year and Date
  2014-11-07 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] 細胞内取込量および DNA 結合能に基づいた制がん tetrazolato 架橋白金 (II)二核錯体の構造活性相関
- Author(s)
  植村雅子，星山美有，古川絢子，樋口善博，米田誠治
- Organizer
  第24回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  京都市
- Year and Date
  2014-06-14 – 2014-06-15
- Data Source
  KAKENHI-PROJECT-24590063
[Presentation] テトラゾール 5 位に置換基を導入した制がんテトラゾラト架橋白金(II)二核錯体の細胞内取り込みと構造活性相関
- Author(s)
  植村雅子，米山弘樹，土屋考弘，星山美有，古川絢子，樋口善博，春沢信哉，米田誠治
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590063

1. UEMURA Masako (70511997)

# of Collaborated Projects: 4 results

# of Collaborated Products: 53 results
2. HIRAMOTO Keiichi (90251793)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. CHIKUMA Masahiko (50025699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. SATO Takaji (80257899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SAITO Yoshihiro (90186974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HARUSAWA Shinya (90167601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. YONEYAMA Hiroki (90627001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
8. YOSHIKAWA Yuko (80291871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
9. 米田誠治 (21750177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 古川絢子 (10455537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 増田秀樹 (50209441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 梶田裕二 (60397495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SUZUKI Toshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 矢守隆夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 旦慎吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 吉川研一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

komeda seiji 米田 誠治

Komeda Seiji 米田 誠治

KOMEDA Seiji 米田 誠治

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窒素の三重結合をマイルドな酸化剤で切断しアンモニアに変換する革新的反応システム

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白金二核錯体の免疫賦活作用機序の解明とDDS化Principal Investigator

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Development of a next-generation platinum-based drug with a markedly high and long-lasting antitumor efficacyPrincipal Investigator

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Drug discovery research based on dinuclear platinum complexes with markedly high antitumor activityPrincipal Investigator

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Development of next-generation anticancer drugs using dinuclear transition metal complexesPrincipal Investigator

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Development of anticancer platinum complexes that recognize a specific region of nucleic acid.Principal Investigator

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Multiple Recognition of DNA by dinuclear platinum complexes with effective cell growth inhibition in cisplatin resistant cell lines

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[Book] パートナー分析化学II 改訂第３版2017

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[Journal Article] Introduction of Fluorine into Antitumor-Active Dinuclear Platinum(II) Complexes Leads to Modulation of In Vivo Antitumor Activity in Mice2022

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[Journal Article] Data on synthesis and structure?activity relationships of tetrazolato-bridged dinuclear platinum(II) complexes2022

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[Journal Article] 創薬分野における白金と白金族元素2021

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[Journal Article] Different Effects of Cisplatin and Transplatin on the Higher-Order Structure of DNA and Gene Expression2019

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[Journal Article] Associative intraligand substitution of anticancer azolato-bridged compounds without a square-pyramidal intermediate: Formation of a unique tetranuclear, μ3-1,2,3-triazolato-N1,N2,N3-bridged Pt(II) compound2019

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[Journal Article] Specific Conformational Change in Giant DNA Caused by Anticancer2017

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komeda seiji 米田誠治

Komeda Seiji 米田誠治

KOMEDA Seiji 米田誠治

[Journal Article] Second- and Higher-order Structural Changes of DNA Induced by Antitumor-Active Tetrazolato-Bridged Dinuclear Platinum(II) 　Complexes with Different Types of 5-Substituent.2013