KOMIYAMA Tomoyoshi 小見山智義

Researcher Number	60439685
Other IDs	https://orcid.org/0000-0003-2138-0084
Affiliation (Current)	2023: 東海大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2009 – 2022: Tokai University, 医学部, 准教授
Review Section/Research Field	Principal Investigator Evolutionary biology / Basic Section 53020:Cardiology-related Except Principal Investigator Medical pharmacy / Basic Section 56030:Urology-related / Circulatory organs internal medicine / Parasitology (including Sanitary zoology) / Cardiovascular medicine / 宇宙生命学
Keywords	Principal Investigator 分子系統樹 / 人為淘汰 / 家畜化 / ドーパミン受容体 / DRD2 / DRD3 / DRD4 / ニワトリ / ドーパミン / 神経調節性失神 … More / アデニル酸シクラーゼ活性量 / アドレナリン受容体遺伝子 / NMS診断 / NMS治療効果 / カフェイン / グルタミン酸 / リピート配列 / 血管抑制型 / 高分解能ホルター心電図 / ヘッドアップチルト試験 / アデニル酸シクラーゼ活性 / 血圧 / 脈拍 / アデニル酸シクラーゼ / ホルター心電図 / カテコラミン受容体遺伝子 … More Except Principal Investigator 自律神経 / アドレナリン受容体 / がん / 薬剤反応性 / 国際情報交換　米国 / ROS / 神経調節性失神 / アドレナリン / アドレナリンレセプター / 遺伝子多型性 / 原虫 / Entamoeba nuttalli / マカク / 疫学 / 遺伝子多様性 / ゲノム / 人獣共通感染症 / アジア / Entamoeba / 中国 / タイ / ミャンマー / ネパール / 薬物耐性 / たこつぼ心筋症 / ストレス / カテコラミン受容体 / カテコラミン / 心交感神経終末分布 / TRPチャネル / 分子シャペロン / HSP-70 / ヒートショックタンパク質 / 皮膚障害 / 抗腫瘍薬耐性 / ゲノム変化 / 国際情報交換米国 / 腎細胞癌 / ND１ / ND1 / ミトコンドリアDNA / 腎がん / ミトコンドリア / ゲノム変異量 / ＮＤ１サブユニット Less

Development of a novel kidney cancer drug targeting mitochondrial molecules
- Principal Investigator
  
  金伯士
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Tokai University
Diagnosis and therapeutic effect of neurally mediated syncope (NMS) using fluctuation of adenylate cyclase activityPrincipal Investigator
- Principal Investigator
  
  小見山智義
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tokai University
The effect of the low ND1 expression in renal cancer cells on the intracellular ROS, tumor metastasis and proliferation
- Principal Investigator
  
  KIM Hakushi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Tokai University
Candidate biomarkers for predicting drug response in cancer treatment
- Principal Investigator
  
  KOBAYASHI Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokai University
The role of dysautonomia and ADR in Takotsubo Cardiomyopathy
- Principal Investigator
  
  Sato Kyoko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tokyo Women's Medical University
The acquisition methods for radiation-resistance by means of light irradiation.
- Principal Investigator
  
  Sakakibara Manabu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  宇宙生命学
- Research Institution
  Tokai University
Studies on geographical distribution and genomic diversity of a new pathogenic Entamoeba species in Asia
- Principal Investigator
  
  TACHIBANA Hiroshi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Tokai University
Targeted therapy for anti-cancer drug resistance: Basic research
- Principal Investigator
  
  KOBAYASHI Hiroyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokai University
The Role of Adrenaline in Neurally Mediated Syncope
- Principal Investigator
  
  SATO Kyoko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Women's Medical University
  Tokai University
Evolutionary Origin and Genetic Differentiation of Dopamine Receptor D2, D3 and D4 Genes of Japanese Domesticated ChickensPrincipal Investigator
- Principal Investigator
  
  KOMIYAMA Tomoyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Tokai University

All 2021 2020 2016 2014 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Clinical Significance of the Head-Up Tilt Test in Improving Prognosis in Patients with Possible Neurally Mediated Syncope2021
- Author(s)
  Ayabe Kengo、Komiyama Tomoyoshi、Hasegawa Misaki、Sakai Tetsuri、Morise Masahiro、Sakama Susumu、Yagishita Atsuhiko、Amino Mari、Ikari Yuji、Yoshioka Koichiro
- Journal Title
  
  Biology
  
  Volume: 10 Pages: 919-919
- DOI
  10.3390/biology10090919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08498, KAKENHI-PROJECT-21K16037
[Journal Article] Examination of gender differences in patients with takotsubo syndrome according to left ventricular biopsy: two?case reports2021
- Author(s)
  Murakami Tsutomu、Komiyama Tomoyoshi、Matsumoto Shingo、Kajiwara Hiroshi、Kobayashi Hiroyuki、Ikari Yuji
- Journal Title
  
  Journal of Medical Case Reports
  
  Volume: 15
- DOI
  10.1186/s13256-021-02856-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08498
[Journal Article] Diagnosis and prevention of the vasodepressor type of neurally mediated syncope in Japanese patients2021
- Author(s)
  Hasegawa Misaki、Komiyama Tomoyoshi、Ayabe Kengo、Sakama Susumu、Sakai Tetsuri、Lee Kyong Hee、Morise Masahiro、Yagishita Atsuhiko、Amino Mari、Sasaki Ayumi、Nagata Eiichiro、Kobayashi Hiroyuki、Yoshioka Koichiro、Ikari Yuji
- Journal Title
  
  PLOS ONE
  
  Volume: 16
- DOI
  10.1371/journal.pone.0251450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08498
[Journal Article] Analysis of the source of aggressiveness in gamecocks2020
- Author(s)
  Komiyama Tomoyoshi、Yoshikawa Masanobu、Yokoyama Keiko、Kobayashi Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 7005-7005
- DOI
  10.1038/s41598-020-63961-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08498
[Journal Article] Analysis to Estimate Genetic Variations in the Idarubicin-Resistant Derivative MOLT-3.2016
- Author(s)
  Komiyama T, Ogura J, Hirokawa T, Kamikuchi H, Asai S, Miyachi H, Kobayashi H.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Pages: 1-13
- DOI
  10.3390/ijms18010012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460657, KAKENHI-PROJECT-15K08109
[Journal Article] Correlation between genotypes of tRNA-linked short tandem repeats in Entamoeba nuttalli isolates and the geographical distribution of host rhesus macaques2014
- Author(s)
  Meng Feng, Tomoyoshi Komiyama, Tetsuo Yanagi, Xunjia Cheng, Jeevan B. Sherchand and Hiroshi Tachibana
- Journal Title
  
  Parasitol. Res.
  
  Volume: 113 Pages: 367-374
- DOI
  10.1007/s00436-013-3664-0
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23117009, KAKENHI-PROJECT-23590496, KAKENHI-PROJECT-24406013
[Journal Article] Possible Association of Human Adrenoceptors Polymorphism in Neurally Mediated Syncope2013
- Author(s)
  Kyoko Sato, Tomoyoshi Komiyama, Hiroyuki Kobayashi, Kuniaki Otsuka
- Journal Title
  
  The Autonomic Nervous System
  
  Volume: (in press)
- NAID
  10031183955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590797
[Presentation] 中年以降で神経調節性失神が疑われる患者におけるヘッドアップチルト検査の有用性2021
- Author(s)
  綾部健吾, 小見山智義, 長谷川実咲, 酒井哲理, 坂間晋, 柳下敦彦, 網野真理, 吉岡公一郎
- Organizer
  第58回日本臨床生理学会総会
- Data Source
  KAKENHI-PROJECT-20K08498
[Presentation] 限局性腎細胞癌におけるミトコンドリアD-loop変異は予後因子として有用か.2020
- Author(s)
  金　伯士、小見山智義、川上正能、新田正広、長谷川政德、河村好章、小路　直、井野元智恵、渡橋　靖、梶原　博、中村直哉、小林広幸、宮嶋　哲
- Organizer
  日本泌尿器科学会
- Data Source
  KAKENHI-PROJECT-18K09180
[Presentation] たこつぼ心筋症における自律神経異常とカテコラミン受容体遺伝子変異2016
- Author(s)
  佐藤恭子, 中岡隆志, 小見山智義, 小林広幸, 佐倉　宏
- Organizer
  第69回日本自律神経学会総会
- Place of Presentation
  熊本県民交流館パレアホール
- Year and Date
  2016-11-10
- Data Source
  KAKENHI-PROJECT-26461092
[Presentation] ヒトアドレナリンレセプター遺伝子多型性と起立性調節障害との関連性について2012
- Author(s)
  佐藤恭子, 小見山智義, 西村芳子,柴田興一, 小林広幸, 大塚邦明
- Organizer
  第65回日本自律神経学会総会
- Place of Presentation
  東京
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-22590797
[Presentation] The Application for Genetic Evaluation of Human Adrenoceptors Polymorphism in Neurally Mediated Syncope2012
- Author(s)
  Kyoko Sato, Tomoyoshi Komiyama, Hiroyuki Kobayashi, Kuniaki Otsuka
- Organizer
  The 35th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Fukuoka
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-22590797
[Presentation] Cultural Domestication of Chicken2011
- Author(s)
  M. Lin, A. Ogura, T. Komiyama
- Organizer
  National Institute of Genetics, Tokyo
- Place of Presentation
  国立情報学研究所学術総合センター(東京)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] Possible Association of Human Adrenoceptors Polymorphism in Neurally Mediated Syncope2011
- Author(s)
  Kyoko Sato, Tomoyoshi Komiyama, Hiroshi Kamiguchi, Ayako Mikami, Hiroyuki Kobayashi, Kuniaki Otsuka
- Organizer
  The 34th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Yokohama
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590797
[Presentation] Cultural Domestication of Chicken2011
- Author(s)
  A.Ogura, M.Lin, T.Komiyama
- Organizer
  Evolutionary Genomics
- Place of Presentation
  国立情報学研究所
- Year and Date
  2011-08-04
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] MHCからみた種内多様性と進化2011
- Author(s)
  小見山智義
- Organizer
  第20回日本組織適合性学会大会
- Place of Presentation
  ツインメッセ静岡
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] Evolutionary Study of Japanese Domesticated Chickens through Dopamine Receptor2011
- Author(s)
  T. Komiyama, H. Iwama, Y. Tateno, H. Kobayashi, T. Gojobori
- Organizer
  SMBE2011京都
- Place of Presentation
  京都大学(京都市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] 日本鶏を用いたドーパミン受容体D2,D3,D4の遺伝的分化に関する解析2011
- Author(s)
  T.Komiyama
- Organizer
  日本進化学会2011
- Place of Presentation
  京都大学
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] Comparative Genomics of Cultural Domesticated Chickens2011
- Author(s)
  A. Ogura, M. Lin, T. Komiyama
- Organizer
  SMBE2011京都
- Place of Presentation
  京都大学(京都市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] Evolutionary Study of Japanese Domesticated Chickens through Dopamine Receptor Gene Analysis2011
- Author(s)
  T.Komiyama
- Organizer
  2011 Annual Meeting of the Society for Molecular Biology and Evolution (SMBE 2011)
- Place of Presentation
  Kyoto University
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] 日本鶏を用いたドーパミン受容体D2, D3, D4の遺伝的分化に関する解析2011
- Author(s)
  小見山智義、岩間久和、舘野義男、小林広幸、五條堀孝
- Organizer
  日本進化学会第13回大会
- Place of Presentation
  京都大学(京都市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] Genomic diversity of culturally domesticated chickens2011
- Author(s)
  A.Ogura, T.Komiyama
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] Comparative Genomics of Cultural Domesticated Chickens2011
- Author(s)
  A.Ogura, M.Lin, T.Komiyama
- Organizer
  2011 Annual Meeting of the Society for Molecular Biology and Evolution (SMBE 2011)
- Place of Presentation
  Kyoto University
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] Genomic diversity of chickens underlying cultural domestication revealed by a CGH2010
- Author(s)
  A. Ogura, T. Komiyama
- Organizer
  Portland State University
- Place of Presentation
  Portland, Oregon, USA
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] The Evolutional Relationship between the Domestication of Fighting Roosters and the repeat variation of Dopamine receptor D42010
- Author(s)
  Tomoyoshi. Komiyama, H.Iwama, Y.Nakamura, K.Sato, H.Kobayashi, Y.Tateno, K.Ikeo, H.Inoko, T.Gojobori
- Organizer
  Molecular Biology and Evolution (SMBE)
- Place of Presentation
  Lyon France
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] ドーパミンレセプターDRD4遺伝子の多型と進化にみる闘争心の起源2010
- Author(s)
  小見山智義、岩間久和、中村洋路、佐藤恭子、池尾一穂、小林広幸、猪子英俊、五條堀孝
- Organizer
  日本遺伝学会第82回札幌大会
- Place of Presentation
  北海道大学(北海道)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] Genomic diversity of chickens underlying cultural domestication revealed by a CGH2010
- Author(s)
  A.Ogura, Tomoyoshi Komiyama
- Organizer
  Evolution 2010
- Place of Presentation
  Portland, Oregon, USA
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] The Evolutional Relationship between the Domestication of Fighting Roosters and the repeat variation of Dopamine receptor D42010
- Author(s)
  T. Komiyama, H. Iwama, Y. Nakamura, K. Sato, H. Kobayashi, Y. Tateno, H. Inoko, K. Ikeo, T. Gojobori
- Organizer
  Annual Meeting of the Society for Molecular Biology and Evolution(SMBE 2010) Lyon France
- Place of Presentation
  Lyon Convention Center
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] ドーパミンレセプターDRD4遺伝子の多型と進化にみる闘争心の起源2010
- Author(s)
  小見山智義, 岩間久和, 中村洋路, 佐藤恭子, 池尾一穂, 小林広幸, 猪子英俊, 五條堀孝
- Organizer
  日本遺伝学会第82回札幌大会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] ドーパミンレセプター遺伝子の多型と闘鶏用シャモにおけるドメスティーケーション成立過程との関係2009
- Author(s)
  小見山智義, 岩間久和, 中村洋路, 池尾一穂, 小林広幸, 猪子英俊, 五條堀孝
- Organizer
  日本進化学会第11回札幌大会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-21570241
[Presentation] ドーパミンレセプター遺伝子の多型と闘鶏用シャモにおけるドメスティケーション成立過程との関係2009
- Author(s)
  小見山智義
- Organizer
  第11回日本進化学会大会(札幌大会)
- Place of Presentation
  北海道大学
- Year and Date
  2009-08-03
- Data Source
  KAKENHI-PROJECT-21570241

1. KOBAYASHI Hiroyuki (60195807)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
2. SATO Kyoko (80335942)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. KIM Hakushi (70609338)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 宮嶋哲 (90245572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YU Shyr

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HANDE Kenneth R.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YOSHIKAWA Masanobu (90276791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. GOJOBORI Takashi (50162136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. IWAMA Hisakazu (20398035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. NAKAMURA Youji (90463182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. TANAKA Tuyoshi (70414919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIKAMI Ayako (50564697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. ISOZAKI Mitsuhiro (90424332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TACHIBANA Hiroshi (10147168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. KOBAYASHI Seiki (70112688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MAKIUCHI Takashi (80587709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Sakakibara Manabu (10135379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 吉岡亨 (70046027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 吉岡公一郎 (30246087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. 永田栄一郎 (00255457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. BOKU Shikei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. CHENG Xunjia

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 宮島哲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 浅井さとみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 宮地勇人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOMIYAMA Tomoyoshi 小見山 智義

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Diagnosis and therapeutic effect of neurally mediated syncope (NMS) using fluctuation of adenylate cyclase activityPrincipal Investigator

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Evolutionary Origin and Genetic Differentiation of Dopamine Receptor D2, D3 and D4 Genes of Japanese Domesticated ChickensPrincipal Investigator

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[Journal Article] Clinical Significance of the Head-Up Tilt Test in Improving Prognosis in Patients with Possible Neurally Mediated Syncope2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Examination of gender differences in patients with takotsubo syndrome according to left ventricular biopsy: two?case reports2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnosis and prevention of the vasodepressor type of neurally mediated syncope in Japanese patients2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of the source of aggressiveness in gamecocks2020

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Journal Title

DOI

Data Source

[Journal Article] Analysis to Estimate Genetic Variations in the Idarubicin-Resistant Derivative MOLT-3.2016

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DOI

KOMIYAMA Tomoyoshi 小見山智義